Manually advanceable radio frequency array with tactile feel
A system for ablating lesions in the interior regions of the human body including a RF catheter and a control system adapted to facilitate the automatic step deployment of an array-type energy delivery system positioned within the catheter. The RF catheter and control system further include an auto array deployment mechanism coupled to the array-type energy delivery system and an impedance and temperature monitoring system. In addition, the system includes a probe positioning device adapted to maintain a RF probe in a desired orientation during ablation procedures.
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The present invention relates to systems and methods for ablating tissue in interior regions of the human body and, more particularly, to systems and methods that facilitate the automatic deployment and placement of a needle array for precise lesion ablation.
BACKGROUND OF THE INVENTIONThermal coagulation of tissue using RF energy is frequently being used to treat maladies within the body such as liver tumor lesions. Physicians frequently make use of catheter-based RF systems to gain access to interior regions of the body. For treatment of large lesions, the catheter-based RF systems commonly employ needle array-type energy delivery devices. However, depending on the size of the lesion to be ablated and, thus, the size of the array used to ablate the lesion, many conventional systems experience difficulty providing an adequate amount of current to cause tissue heating and coagulation. To address this problem, many manufacturers simply supply a larger generator to provide an adequate amount of current to cause tissue heating and coagulation. Others address the large array problem by having the user step deploy their array at a measured and stable rate. In such a procedure, the physician must carefully apply ablating energy to the element for transmission to the tissue to be ablated, at each predetermined distance, for a fixed period of time and/or until the tissue reaches a desired temperature. A heated center is created as a result, which further heats the target region when the array is fully deployed. This manual procedure tends to be confusing because of the multiple parameters that need to be observed prior to moving on to the next deployment location.
Physicians may experience other difficulties when the lesion to be ablated is close to the dermis or is in tissue that is light in density. When RF catheters or probes are pushed into dense body tissue such as the liver, the probes tend to be inserted deeply enough to remain upright during ablation. However, when ablation procedures, including ablation of some liver lesions, are performed relatively close to the dermis or are performed in tissue that is especially light in density, such as the lung, the physician may have a difficult time maintaining the catheter or probe in its initial orientation. As a result, the physician must either stack pads or gauze under the probe or hold the probe in place during the entire ablation procedure, which is typically about 6-15 minutes. If the physician chooses not to hold or support the probe during such procedures, the probe may sag and could push the energy delivery needles or tines into the dermis layer or other tissue areas not meant to be ablated.
Thus, a need exists for controlling the advancement of the needle array such that the array moves forward to contact new tissue areas once the tissue area presently in contact is ablated. In addition, a need exists for maintaining the probe in a desired orientation for a hands-free mode of operation for the physician.
SUMMARY OF THE INVENTIONThe present invention is directed to improved systems and methods that facilitate the automatic deployment and placement of a needle array for precise ablation of body tissue using RF energy. The RF ablation system of the present invention tends to eliminate any confusion as to when the needle array should be further deployed into the tissue during step deployment ablation procedures, minimize the time to carry out such procedures, and eliminate the need for insertion track bleeding management techniques following such procedures. In one innovative aspect of the present invention, a needle array-type energy delivery system is automatically advanced or step deployed under temperature and/or impedance feedback control. In another innovative aspect of the present invention, a catheter based RF ablation system includes an auto array deployment or advancement system which may comprise a servo, an electromagnetic, an electro-pneumatic, a hydraulic, or the like, actuating mechanism, or a stepper motor. In a preferred embodiment of the present invention, a catheter based RF ablation system includes a catheter having an elongate tube and a handle connected to the tube, a needle array slidably received in the tube and handle, a servo actuated drive mechanism mounted in the handle and coupled to the needle array, and a control system coupled to the servo actuated drive and needle array. The control system preferably comprises a RF energy source, a drive controller, and a temperature and/or impedance monitoring module for step deployment at predetermined temperature and/or impedance values. The control system may also include a timer for step deployment at predetermined intervals.
In operation, the catheter is inserted through intervening tissue until it reaches a treatment site, such as a tumor lesion within the liver, where the needle array is initially manually deployed to a first fixed diameter. The RF power source is activated to a preferred power level while the temperature/impedance monitoring module of the control system simultaneously monitors the temperature and/or impedance measurements coming from the needle array. Once a predetermined temperature and/or impedance is achieved, the drive controller activates the servo actuated drive mechanism to advance the needle array further into the tissue to be ablated. Alternatively, the drive controller activates the servo actuated drive mechanism to advance the needle at predetermined intervals. This active advancing process is repeated, until the array is fully deployed. Once fully deployed, the needle array acts in accordance with conventional ablation procedures.
In another embodiment of the present invention, the system preferably includes a probe positioning device capable of maintaining the RF ablation probe in a desired orientation and preventing the ablation of tissue not meant to be ablated. The probe positioning device preferably comprises a probe holder adapted to slidably receive a RF probe and supports connected to the probe holder. The probe holder being adapted to receive a RF probe.
Further objects and advantages of the present invention will become more apparent from the following detailed description taken with the following drawings.
BRIEF DESCRIPTION OF THE DRAWINGS
Referring in detail to the drawings, an illustrated embodiment of an improved RF ablation system of the present invention is shown. Turning to
Turning to
As depicted in
For example, such tactile feel may be provided by a spring plunger with a ball detent built into the handle (22) wherein the spring loaded ball would ride along a smooth wall of an inner handle. Recess or detent locations would be calibrated along the inner handle to deploy the array a predetermined diameter. Alternatively, a tab or o-ring connected to the inner surface of an outer handle could be used to locate recesses or detents formed on the inner handle. Another alternative may include radial grooves on an inner or outer handle that enables the probe to be rotated and held in place after the array have been deployed a predetermined diameter. T
The control system (14) preferably comprises a RF power source (38), such as a generator, a drive controller (42) coupled to the power source (38), an impedance and/or temperature monitoring module (40) coupled to the power source (38) and the drive controller (42), and a variety of displays to indicate temperature, impedance, needle position, elapsed time, and the like. The drive controller (42) may be built into the RF generator or may be a stand alone unit. A first cable (32), interconnected to the power supply (38), extends from the control system (14) to the proximal end (23) of the shaft (21) of needle array (20) to supply RF power to the needles (27) and (29) of the needle array (20). A second cable (34), interconnected to the monitoring module (40), extends from the control system (14) to the proximal end (23) of the needle array (20) to communicate temperature or impedance measurements from the needles (27) and (29), which preferably include temperature and/or impedance measuring capabilities. A third cable (36), interconnected to the drive controller (42), extends from the control system (14) to the servo motor of the driver (28) in the handle (22) of the catheter (12) to control or actuate the driving gear (33), which in turn causes the deployment or retraction of the needle array (20).
The RF ablation system (10) of the present invention is preferably operated in a manner that increases the current density applied to the tissue to be ablated. The system (10) preferably uses impedance or temperature feedback to control the servo actuated array deployment mechanism (30) resulting in the automated step deployment of the needle array (20). Because the deployment of the needle array (20) is fully automated, any confusion associated with conventional step deployment methods used with conventional needle array-type devices tends to be eliminated.
In operation, the distal end (18) of the catheter (12) is inserted through intervening tissue until it reaches a treatment site, such as a tumor lesion within the liver. Once the distal end (18) of the catheter (12) is in place, the needle array (20) is preferably manually deployed to extend the needles (27) and (29) to a first fixed diameter. If the device includes internal detents or steps, the needle array (20) is advanced until a step or detent is encountered. With return electrodes properly in place on the patient, the RF generator of the power source (38) is activated to a preferred power level while the temperature/impedance monitoring module (40) of the control system (14) simultaneously monitors the temperature and/or impedance measurements coming from the needles (27) and (29). Once a predetermined temperature and/or impedance is achieved, while RF power is still being delivered, the drive controller (42) of the control system (14) activates the servo motor of the driver (28) and, thus, actuates the driving gear (29) to advance the needle array (20) forward a predetermined distance and, thus, advance the needles (27) and (29) further into the tissue to be ablated. Alternatively, the needles (27) and (29) may be advanced further into the tissue to be ablated after a predetermined period of time has elapsed. This active advancing process is repeated, as shown in
After completion of the ablation procedure, the needle array (20) may be automatically fully retracted into the elongate tube (16) of the catheter (12) prior to retrieval of the catheter (12). Alternatively, the needle array (20) may be retracted automatically to a partially deployed state in which the needles (27) and (29) extend slightly beyond the distal end (18) of the catheter (12). In the partially deployed state, the catheter (12) may be retrieved while the needle array (20) ablates the catheter insertion track to minimize or eliminate post procedure bleeding along the insertion track.
As indicated herein, the RF ablation system (10) of the present invention advantageously tends to 1) eliminate any confusion as to when the needle array (20) should be further deployed into the tissue, 2) minimize the time to carry out such procedures, and 3) eliminate the need for gelfoam or comparable insertion track bleeding management techniques.
When RF probes, such as the catheter (12) of the present invention, are pushed into dense body tissue such as the liver, the probes tend to be inserted deeply enough to remain upright during ablation. However, some ablation procedures, including the ablation of some liver lesions, are performed relatively close to the dermis or may be performed in tissue that is especially light in density, such as the lung. As a result, the probe or catheter (12) may have a difficult time maintaining the orientation initially set up by the physician, requiring the physician to hold the probe in place during the entire ablation procedure, which is typically about 6-15 minutes, or stack pads or gauze under the probe to support the probe. If the physician chooses not to hold or support the probe during such procedures, the probe may sag and could push the needles (27) and (29) into the dermis layer or other tissue areas not meant to be ablated. For example,
To assist in the deployment of the RF catheter (12) of the present invention and avoid ablating tissue not meant to be ablated, the present invention further includes a probe positioning device (100). As depicted in
As depicted in
In an alternative embodiment shown in
While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof have been shown in the drawings and are herein described in detail. It should be understood, however, that the invention is not to be limited to the particular form disclosed, but to the contrary, the invention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the appended claims.
Claims
1-26. (canceled)
27. A radio frequency probe, comprising:
- an elongate tube;
- a handle connected to the tube,
- a needle array received in the tube, and
- an array deployment mechanism at least partially contained within the handle and configured to incrementally deploy the needle array out from the elongate tube at a plurality of predetermined positions, wherein the deployment mechanism comprises one or more mechanical elements for providing a user with tactile feel of when the needle array is at the predetermined positions.
28. The radio frequency probe of claim 27, wherein the elongate tube is configured to be percutaneously inserted through tissue.
29. The radio frequency probe of claim 27, wherein the needle array comprises a shaft and individual tines formed at a distal end of the shaft.
30. The radio frequency probe of claim 27, wherein the deployment mechanism comprises a driven member mechanically coupled to the electrode array and a driving member mechanically coupled to the driven member.
31. The radio frequency probe of claim 27, wherein the driving member and driven member each comprises a gear.
32. The radio frequency probe of claim 27, wherein the handle fully contains the
31. The radio frequency probe of claim 27, wherein the one or more mechanical elements comprises one or more stop.
32. The radio frequency probe of claim 27, wherein the one or more mechanical elements comprises one or more detents.
33. An ablation system, comprising:
- the radio frequency probe of claim 27; and
- a source of radio frequency energy operably coupled to the radio frequency probe.
34. A tissue ablation probe, comprising:
- an elongate member,
- a handle carried by the elongate member;
- a deployable ablative element carried by the elongate member; and
- a deployment mechanism at least partially contained in the handle and configured to incrementally deploy the ablative element in the distal direction at a plurality of predetermined positions, wherein the deployment mechanism comprises one or more mechanical elements for providing a user with tactile feel of when the needle array is at the predetermined positions.
35. The radio frequency probe of claim 34, wherein the elongate tube is configured to be percutaneously inserted through tissue.
36. The radio frequency probe of claim 34, wherein the needle array comprises a shaft and individual tines formed at a distal end of the shaft.
37. The radio frequency probe of claim 34, wherein the deployment mechanism comprises a driven member mechanically coupled to the electrode array and a driving member
38. The radio frequency probe of claim 34, wherein the driving member and driven member each comprises a gear.
39. The radio frequency probe of claim 34, wherein the handle filly contains the deployment mechanism.
40. The radio frequency probe of claim 34, wherein the one or more mechanical elements comprises one or more stop.
41. The radio frequency probe of claim 34, wherein the one or more mechanical elements comprises one or more detents.
42. The radio frequency probe of claim 34, wherein the ablative element comprises one or more electrodes.
43. A tissue ablation system, comprising:
- the tissue ablation probe of claim 34; and
- a source of ablation energy operably coupled to the tissue ablation probe.
Type: Application
Filed: Nov 14, 2005
Publication Date: May 4, 2006
Applicant: SCIMED LIFE SYSTEMS, INC. (Maple Grove, MN)
Inventors: Robert Garabedian (Tyngsboro, MA), Robert Rioux (Ashland, MA)
Application Number: 11/273,950
International Classification: A61B 18/14 (20060101);