Ultrasonic diagnosis apparatus
An ultrasonic diagnosis apparatus comprises an ultrasound probe, a transmitter (including a transmitting pulse generator and a transmitting beamformer), a receiver (including a preamplifier and a receiving beamformer), a CFM processor (including a moving-element signal extractor and a velocity corrector), a tomographic image processor, and a display unit. The apparatus scans a desired section of a subject by transmitting and receiving an ultrasound pulse to and from the subject, and displays images obtained by the scanning. The velocity corrector comprises a pulsation-characterizing-velocity (velocities of a moving element) calculator, a representative velocity (reference velocity) calculator, and a corrector to correct the velocities of the moving element based on the standard velocity. The corrected velocity data is visualized on display unit. The ultrasonic diagnosis apparatus makes it possible to display the pulsatility of blood vessels in an easier and useful way.
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1. Field of the Invention
The present invention relates to an ultrasonic diagnosis apparatus capable of not only effectively displaying dynamic states of flow of blood in a subject to be examined, particularly, pulsation of the flow of blood, but also three-dimensionally displaying pulsatile flows of blood in the subject.
2. Description of Related Art
An ultrasonic diagnosis apparatus has normally various types of displaying images, as has been widely known, which can be used for diagnosis on ultrasound images. Such types of displaying images include a CFM (Color Flow Mapping) mode used for displaying blood flow images, as well as tomographic image modes, such as a B-mode, used for displaying tomographic images.
Among these modes, the CFM mode is prepared for displaying two-dimensional blood flow information in real time. In this mode, generally, flows of blood approaching to the ultrasound probe are displayed in red on a monitor, while flows of blood going away from the probe are displayed in blue on the monitor, so that information about blood flow is visually distinguishable.
The following describes the principle and an outline of process for displaying information in relation to blood flow on the CFM mode. As conventionally well known, an ultrasonic diagnosis apparatus obtains echo signals sequentially in time by performing ultrasound scanning at each location (direction) in a subject to be examined a plurality of times (N-times). Then, from the echo signals obtained sequentially in time, the apparatus detects information in relation to velocity and/or scattering power of blood flow at a desired depth in the scanned region on the basis of the Doppler technique. That is, scanning the same location in the subject at predetermined intervals provides Doppler signals expressed as a quantity of phase shift per unit time of signals (blood flow signals) reflected from blood cells. The Doppler signals thus obtained are converted to data of velocity and/or scattering power of blood flow.
More precisely, applying quadrature phase detection to the echo signal at each time of ultrasound scanning with the use of mixers and LPFs (Low Pass Filters) provides an I (In-Phase) signal and a Q (Quadrature-Phase) signal, both of which are extracted as Doppler signals.
The extracted Doppler signals contain by mixture a reflected wave signal from objects in motion (moving elements), such as blood cells, and a second reflected wave signal (called Clatter Signals) from almost non-moving fixed objects, such as the blood vessel wall and organ parenchyma. Of these wave signals, the reflected wave signal from the objects in motion contains a Doppler shift. In contrast, the reflected signal from the fixed objects hardly contains a Doppler shift, and is so high in its intensity that the signal is a dominant in the detected signal.
Therefore, clatter components representing the reflected wave from the fixed objects are eliminated through an MTI (Moving Target Indicator) filter by taking advantage of a difference in the quantity of Doppler shift, a blood flow Doppler signal can be efficiently extracted. Then, through analysis of the frequency of this blood flow Doppler signal, i.e., N-pieces of Doppler data composed of xi (I signal) and yi (Q signal) at each depth (where i=1, 2, . . . , N), a mean derived from the spectra (i.e., a Doppler frequency), a dispersion of the spectra, or a reflection intensity (power) from blood cells can be calculated.
For this frequency analysis, an autocorrelation function is normally used. A frequency analysis technique that uses the autocorrelation function will now be exemplified. As above described, the blood flow Doppler signal obtained by eliminating its clatter components at the MTI filter is expressed by a complex number zi composed of Doppler data xi and yi, each is N-pieces in number, and expressed by the equation of:
where ai is an amplitude, fd is a Doppler frequency, Trn is intervals of transmission of ultrasound pulses along an arbitrary raster direction, and ø is an initial phase respectively. For the sake of explanatory convenience, it is assumed that the Doppler frequency fd is constant over the N-pieces Doppler data, still maintaining the generality of the equation.
According to the above equation (1), the phase rotation of the complex number zi per unit time provides a Doppler frequency fd. Where a mean complex autocorrelation function for the N-piece Doppler data is:
Z=X+jY=A·exp[jη], (2)
the following equation can be obtained:
The Doppler frequency fd is therefore expressed as:
fd=(2π) Trm−1tan−1(Y/X). (4)
X=Σ(xixi+1+yiyi+1)
Y=Σ(xixi+1−yiyi+1)
By employing this Doppler frequency fd, the equation of:
Vd=fd·c/(2fM·cosθ) (5)
can be obtained, so that a Doppler velocity Vd is converted using this equation (5). In this equation (5), c, fM and θ indicate a sound velocity, the frequency of a reference signal at the mixers, and an angle formed between an ultrasound beam and each blood flow (hereinafter referred to as a “Doppler angle”), respectively.
In the case of a CFM mode, due to difficulty in obtaining Doppler angles at each position in the space of an image, which vary position by position therein, the correction of Doppler angles is omitted from the computation on the foregoing equation (5). In other words, in the CFM mode, the Doppler velocity Vd can be calculated based on the equation of:
Vd=fd·c/(2fM) (6),
and is subjected to display in colors. Consequently, where the Doppler angle is larger, a calculated value becomes smaller than its original correct velocity, with the result that the Doppler velocity Vd is subject to display based on color intensities representing slower velocity states (this is called “angle dependency”).
Blood flow velocities obtained as described above are two-dimensionally displayed on a monitor, normally, together with a B-mode topographic image displayed as a background.
In recent years, three-dimensional image display in ultrasonic diagnosis apparatuses has been extensively researched and developed, and it has been possible to three-dimensionally display a power image of blood flow. For such a display, for acquiring three-dimensional data, a hand scanning technique by which an electronic scanning probe with one-dimensionally arrayed transducers is used, for example.
To operate this hand scanning, while being electronically scanned in the direction along the transducer array, an operator moves his or her hand holding the probe so that the probe is moved to orthogonal directions to the transducer array direction.
However, the display on the current CFM mode has encountered the following problems.
First, in recent years, as various types of diagnostic methods have been advanced, there are demands for a display technique that allows a user to identify a blood vessel as an artery, portal vein, or vein in a steadier and easier manner. In particular, to identify a blood vessel as described above by using an ultrasound wave, it is considered effective to observe pulsation appearing in blood flow.
As one conventional examination method for examining pulsatility of this kind of blood vessel, one display method called “pulsatility index (PI)” has been known. The PI is an index that quantifies the extent of change in a blood flow velocity per heartbeat. Since peripheral circulatory resistance in blood vessels is reflected in the PI, it is deemed effective for early detection of dysgenesis of fetuses in the obstetrical department and for differential diagnosis of tumor in the abdominal part (refer to, for example, a Japanese Patent Laid-open (KOKAI) Publication No. H05-317311).
Other conventional examination methods are provided to examine the pulsatility of blood vessels, for example. One method is to display an acceleration of blood flow calculated from two frames of blood flow velocity data which are adjacent in time and stored in a frame memory (Japanese Patent Publication No.2768959). Using this method, information about the pulsation of acceleration of a blood flow can be added on two-dimensional color flow map information or three-dimensional display information based on the CFM mode. Another method is proposed by an ultrasound imaging method and apparatus that is able to display an image of intensity of the pulsation appearing in the moving velocity of an echo source (Japanese Patent Application Laid-open (KOKAI) Publication No.2000-152935). This method comprises the steps of detecting a moving velocity of an echo source based on Doppler shifts of received echoes, detecting intensities of the pulsation appearing in the moving velocity calculated on moving velocities at the current and past temporal phases, and producing an image indicative of the detected intensities of the pulsation. Those methods have not, however, reached a level of practical use yet.
Besides, the present CFM mode has a difficulty to clearly display the pulsatility of blood flow in displaying its power. It is considered that displaying the velocities of blood flow still provides distinguishable observation with respect to the pulsatility. In other words, temporal changes in the colors indicative of velocities shows that there is pulsatility in a blood flow to be observed, while no temporal changes in such colors shows that, there is no pulsatility in the blood flow. However, there are many cases that make it difficult a clear discrimination of blood flows even if carefully watched, thereby still lacking practically. Whichever of the display techniques are chosen, a more convenient display technique is required to provide the pulsatility of blood flow.
Especially in the case of peripheral blood vessels, their blood flow velocities are relatively lower, amounts of changes in the velocities showing the pulsatility are also small, even in arteries. It is therefore considerably difficult to distinguish an artery from a vein or vise versa on a displayed image. In addition, displaying the velocity has the problem of the angle dependency if the Doppler angle is larger, as described before, resulting in that detected velocities are smaller than their original correct velocities. It is therefore very difficult to detect the pulsatility, like the situation in peripheral blood vessels.
On the other hand, in the foregoing three-dimensional display, a further advanced display rather than the simple display of blood vessels is demanded. Such advanced display techniques include a display technique that has the capability of classifying the types of blood vessels, such as artery, portal vein, or vein. For this purpose, it is also considered advantageous that such display involves pulsatile flows of blood, which requires an ultrasonic diagnosis apparatus that is able to three-dimensionally display the pulsatility.
SUMMARY OF THE INVENTIONThe present invention has been made in consideration with the above problems, and an object of the present invention is to provide an ultrasonic diagnosis apparatus that is able to effectively display the pulsatility of blood vessel in a simple and easy way.
A further object of the present invention is to provide an ultrasonic diagnosis apparatus suitable for displaying the pulsatility of blood vessel in a three-dimensional manner.
In order to achieve the objects, the ultrasonic diagnosis apparatus according to the present invention is characteristic of having, as basic constituents, scanning means for scanning a subject to be examined while transmitting and receiving an ultrasound pulse to and from the subject; means for obtaining in sequence a plurality of velocities of a moving element within the subject based on reception signals acquired by the scanning performed by the scanning means; processing means for computing a reference velocity based on the plurality of velocities obtained from during a predetermined period of time and correcting each of the velocities of the moving element using the reference velocity so that data of the corrected velocities is obtained; and displaying means for displaying the data so that the data is updated a plurality of times during the predetermined period of time.
In the present invention, it is possible that the processing means has extracting means for extracting a signal of the moving element from the reception means.
In the present invention, by way of example, an instantaneous velocity can be adopted as a “velocity of a moving element” (that is, a velocity indicating a characteristic of the pulsation) within a subject to be examined. In addition, to a “reference velocity” (that is, a representative velocity), assigned is at least one selected from 1) a mean of velocities acquired during a predetermined period of time or an absolute value of the mean thereof, 2) a mean of absolute values of velocities acquired during a predetermined period of time, 3) an RMS (Root Mean Squire Value) value of velocities acquired during a predetermined period of time, 4) a value or an absolute value thereof, which is calculated by applying any one of an FIR (Finite Impulse Response) filter, IIR (Infinite Impulse Response) filer, and a non-linear filter to velocities acquired during a predetermined period of time or absolute values of the velocities, and 5) a vectorial mean of velocities acquired from a predetermined period of time or an absolute value of the mean. Preferably, the predetermined period of time is one heartbeat of the subject, a period of time corresponding to one heartbeat, or a period of time during which the effects identical to that in one heartbeat are provided.
In the present invention, the processing means comprises at least one of 1) means for dividing the velocities of the moving element by the reference velocity, and 2) means for converting the velocities of the moving element to values relative to the reference velocity.
Preferably, the processing means according to the present invention has correction means for correcting the aliasing of the velocities. Further, the present invention may have moderation means for moderating temporal changes in the data obtained by the processing means. It is preferred that the scanning means according to the present invention has scanning means for scanning one section of the subject at the number of frames larger than a value indicated by an inverse number of a period of time corresponding to an ejection period of cardiac pulsation.
In the present invention, the display means is configured to display a two-dimensional image based on the data obtained by the processing means.
An ultrasonic diagnosis apparatus according to another aspect of the present invention comprises scanning means for three-dimensionally scanning one section of a subject to be examined a plurality of times corresponding to one heartbeat while transmitting and receiving an ultrasound pulse to and from the subject; means for obtaining in sequence velocities of a moving element within the subject based on reception signals obtained three-dimensionally by the scanning means; processing means for computing a reference velocity based on the plurality of velocities obtained from during a predetermined period of time and correcting each of the velocities of the moving element using the reference velocity so that data of the corrected velocities is obtained; and displaying means for displaying at least a three-dimensional image based on the data so that the image is updated a plurality of times during the predetermined period of time.
In the present invention, in the case that the three-dimensional scan is carried, it is preferred that the scanning means is configured to three-dimensionally scan the subject through an electrical scan by means of a two-dimensional array type of transducer. It is also preferred that the velocities of the moving element are set to a maximum velocity during a predetermined period of time. In the case of displaying a three-dimensional image of information about the pulsatility of the subject in the present invention, it is preferred that such information is unchangeable over cardiac time phases of the subject.
As another aspect of the present invention, the ultrasonic diagnosis apparatus further comprises means for obtaining a tomographic image of the section of the subject, and the display means is able to display on the same monitor the tomographic image and the image of data obtained by the processing means. In this case, it is more effective if the display means is configured to display on the tomographic image the image of data obtained by the processing means in a superposition manner. Furthermore, for three-dimensional display in the present invention, the tomographic image may be a three-dimensional image. In the present invention, it is preferable that an image based on the data obtained by the processing means is depicted in colors.
As another aspect of the present invention, it is possible to display pieces of information formed by combining the data obtained by the processing means and power information of scattering echoes from the moving element within the subject. In this configuration, the display can be more effective in cases where the ultrasonic diagnosis apparatus has means for displaying a color bar mapped not only by a hue indicative of a lower velocity when a magnitude of the data obtained by the processing means is nearly equal to or less than the representative velocity but also by other hues indicative of higher velocities as the magnitude of the data obtained by the processing means becomes larger than a value nearly equal to the representative velocity.
As another aspect of the present invention, it is preferred that the image of the data obtained by the processing means and an information of power information of scattering echoes from the moving element within the subject are displayed by mixture. It is also possible to display by mixture an image of the power information and an image of information formed by combining the data obtained by the processing means and the power information. In this case, it is desired that both of a color bar for the data obtained by the processing means and another color bar for the power information are displayed together. It may also be possible to display together both of a color bar indicative of a combination of the data obtained by the processing means and the power information and another color bar for the power information. A more effective example is that setting means is used to set an upper limit and a lower limit on the color bar for the data obtained by the processing means, and/or at least one of an upper limit, a lower limit, and an aliasing velocity on the color bar for the data obtained by the processing means is displayed.
As described above, in the ultrasonic diagnosis apparatus according to the present invention, the scanning means operates to scan a section to be imaged of a subject through a plurality of times of transmission and reception of an ultrasound pulse along the same raster direction of the raster directions required for the scanning within the subject. The processing means thus operates as follows. A tissue signal is removed from a reception signal obtained by the scanning conducted by the scanning means, at every sample point of the section that has been scanned, so that a blood flow signal is extracted. Based on this blood flow signal, velocities of a moving element (i.e., velocities which are characteristic of the pulsation) and a reference velocity (i.e., a representative velocity) are figured out. And the velocities of the moving element are corrected using the reference velocity. Therefore, under the operations of the display means, data thus-obtained at individual sample points is depicted as for example a two-dimensional or three-dimensional image.
Accordingly, the velocities of a moving element are corrected based on the reference velocity, which makes it possible that the pulsatility of slower-speed blood flows, such as flows passing the peripheral blood vessels, is depicted distinctively. Further, a Doppler angle dependency is also removed, with the result that the pulsatility of blood flows is clearly provided even if a Doppler angle becomes larger. Because the data that has been subjected to the correction is used for the display, the pulsatility can be depicted easily and more effectively, compared to the conventional CFM power images and velocity images. It is therefore possible to upgrade visibility for the artery, portal vein and vein, thus contributing to an improved diagnostic performance.
In particular, provided that instantaneous velocities are used as the velocities of a moving element, the display of the pulsatility becomes excellent, in which dynamic pulsatile changes are depicted in real time, with the visibility for the pulsatility enhanced. Suitable for the reference velocity are: a mean of instantaneous velocities acquired during a predetermined period of time or an absolute value of the mean thereof; a mean of absolute values of instantaneous velocities acquired during a predetermined period of time; an RMS (Root Mean Squire Value) value of instantaneous velocities acquired during a predetermined period of time; a value or an absolute value thereof, which is calculated by applying any one of an FIR (Finite Impulse Response) filter, IIR (Infinite Impulse Response) filer, and a non-linear filter to instantaneous velocities acquired during a predetermined period of time or absolute values of the instantaneous velocities; and a vectorial mean of instantaneous velocities acquired from a predetermined period of time or an absolute value of the mean.
In addition, preferably, the predetermined period of time is a period of one heartbeat or a period of time corresponding to one heartbeat. Alternatively, the predetermined period of time may be any other period of time selected to have the similar effects to the period of time of one heartbeat. The simplest and most useful technique for the correction is to use the division. Namely, utilizing the division allows the pulsatility of slower blood flows such as peripheral blood flows to be depicted clearly, and the problem resulting from the Doppler angle dependency can be removed. Moreover, by correcting the aliasing of velocities, the present invention is also applicable to faster velocities of moving bodies, thus making the application more effective.
In addition, in cases where it is felt that the real-time display of the pulsatility is hard to observe due to faster temporal changes thereof on the image, such temporal changes on the image can be moderated to raise the visibility.
Further, a specified section of the subject is scanned at the number of frames larger than a value indicated by an inverse number of a period of time corresponding to an ejection period of cardiac pulsation. This scanning makes sure that the ejection period is traced without failure, whereby the pulsatility can be depicted in a steadier manner and a diagnostic performance can be improved. The reason is as follows. The pulsation is caused by the pumping action of the heart and the ejection period of one cardiac cycle is characteristic of the pulsation. A blood flow speed at the vein and the portal vein is almost constant over one cardiac cycle, while a blood flow speed at the artery increases sharply and then decreases in the ejection period, and then gradually decreases until the next ejection period begins. It is therefore very significant to steadily track the ejection period for detecting the pulsatility.
For obtaining a three-dimensional image, the scanning means is operated to scan a subject in a three-dimensional manner, while the display means is operated to display a three-dimensional image based on the data obtained through the scanning. The three-dimensional scanning carried out by the scanning means requires a specified section of the subject to be scanned a plurality of times. This scanning is able to provide both of velocities of a moving element and a reference velocity at each section to be scanned, three-dimensional data that has been corrected, and a three-dimensional image according to the present invention.
In cases where such a three-dimensional image based on information about the pulsatility of a blood flow within a subject is displayed through the three-dimensional scanning, it is preferred that a specified section of the subject is scanned three-dimensionally a plurality of times. This manner will provide a three-dimensional image in which the pulsatility is depicted with higher accuracy, whereby such an image is able to contribute to an enhanced diagnostic performance.
In order to effectively implement the three-dimensional scan of the present invention, the most suitable technique is to use a two-dimensional array type of transducer to three-dimensionally scan a subject under an electrical staring scanning.
Furthermore, when a maximum velocity detected during a period of time is used as velocities of a moving element, a higher-pulsatility blood vessel, such as the artery, is always depicted in hues showing higher pulsatility, whilst a lower-pulsatility blood vessel, such as the portal vein and vein, is always depicted in hues showing lower pulsatility. Accordingly, images characteristic of the pulsatility, which are acquired at each of the cardiac time phases, can be obtained at any time. Hence, it is still preferable that such an image can be combined with the foregoing three-dimensional image, wherein two-dimensional pulsatile images, which become fundamental images for a three-dimensional image, can be acquired irrelevantly to changes in the cardiac time phase. Therefore, a three-dimensional pulsatile image can be constructed easily. In general, when information indicative of the pulsatility of a blood flow within a subject is acquired as information irrelevantly to changes in the cardiac time phase, a three-dimensional pulsatile image can be constructed easily.
In the case of displaying the foregoing two-dimensional and three-dimensional pulsatile images, means for acquiring a topographic image at a section of a subject can be provided as well. In such a construction, under the operations of the display means, both of the tomographic image and an image on the data obtained by the processing means can be depicted on the same monitor. This makes it easier to identify the position of a blood vessel to be observed, thus providing an image of highly improved visibility. Hence a further enhancement of a diagnostic performance is possible.
In particular, it is more effective when the display means operates to overlay, on the tomographic image, the image on the data obtained by the processing means. If performing the three-dimensional display, the tomographic image may be of a three-dimensional tomographic image, not being limited to a two-dimensional tomographic image. When the pulsatile image to be overlaid is depicted in colors, it is sure that the visibility will be upgraded more, being useful in observing the image. In this configuration, the data obtained by the processing means may be combined with scattering power detected from a moving element within a subject so that an image expressing the combination is depicted in colors. This display is able to largely raise a visual effect on the image.
As another feature, the reference velocity may be a mean of the velocities that have been detected. In such a construction, when magnitudes of the data obtained by the processing means are close to a representative velocity, the above mean is almost equal to a velocity detected at each of the cardiac time phases of both the vein and portal vein. In the case of the artery, however, the above mean is almost equal to a velocity detected at each of the cardiac time phases other than the ejection period. Considering to this fact, it is preferable to display a color bar mapped not only by a hue indicative of a lower velocity when magnitudes of the data obtained by the processing means are nearly equal to or less than a reference velocity but also by other hues indicative of higher velocities as the magnitude of the data obtained by the processing means becomes larger than a value nearly equal to the reference velocity. This display of the color bar will make it possible that the hues assigned to the pulsatility and non-pulsatility is distinctively distinguished one from the other, resulting in that the pulsatility can be distinguishably visualized with ease, thus contributing to a more improved diagnostic performance.
By the way, breathing, heartbeats, and/or others may cause an organ to move within a subject. If such a movement happens in connection with blood vessels, such as peripheral blood vessels or blood vessels whose Doppler angles are larger, it is conceivable that blood flow signals are obliged to stop detecting temporarily or depending on some particular cardiac time phases. In such a situation, a reference velocity cannot be determined, so that velocities of a moving element cannot be corrected. In other words, it is impossible to correct the velocities, but only the detection of velocities (accordingly, instantaneous blood flow signals) of a moving object is possible.
In such a situation, thought the data obtained by the processing means cannot be subjected the display of an image thereof (that is, an image indicative of the pulsatility), power display that represents the existence of a blood flow(s) is at least possible. Hence, the following display strategy can be given. Namely, in cases where velocities of a moving element have been corrected, the data obtained by the processing means is then subjected to displaying images thereof. By contrast, in cases where such velocities are no longer corrected, though blood flow signals have been detected, the corrected velocities are made to undergo the power display. In other words, an image on the data obtained by the processing means and a power image are displayed by mixture.
This mixing display technique enables the visualization of all the blood vessels that have been detected. To be specific, the pulsatility can be depicted toward blood vessels if the velocities of blood flowing therethrough have been corrected. In that case, the pulsatility can be visualized at higher vessel detectability, thus being able to largely improve a diagnostic performance. When coloring is applied to both of the pulsatile image and the power image, the visibility to the mixed image can be more raised. Alternatively, the depiction of a color image concerning information produced by combining the data obtained by the processing means and scattering power detected from a moving element within a subject may be applied to a region at which it has been possible to correct the velocities. This display technique will further raise a visual effect on the image.
In the above display mode, both of a color bar showing the pulsatility and another color bar showing the power should be put on the image. The former color bar will help a viewer distinguish the pulsatility from the other with ease. In addition, in cases where the depiction of a color image concerning information produced by combining the data obtained by the processing means and scattering power detected from a moving element within a subject is applied to a region at which it has been possible to correct the velocities, one color bar can be adopted such that hues showing the pulsatility are taken longitudinally and other hues showing the power are taken laterally, for instance. This two-dimensional color bar and the color bar for the power can both be placed on the same image(s).
In association with the display of the above color bars, upper and lower limits of the pulsatility can be put on the color bars. When such display of the limits is carried out, the relationship between the hues and degrees of the pulsatility is clearly specified, thus allowing an observer to easily recognize a degree of the pulsatility, thus contributing to an enhanced diagnostic performance. In addition, using means for setting values to the upper and lower limits on a color bar, an observer can give proper values to those limits. This will lead to a more effective display of the pulsatility, whereby an enhanced diagnostic performance can be expected. Additionally putting an aliasing velocity on a color bar allows a velocity range to be set adequately, which results in a steadier detection of the pulsatility, with the delectability improved.
As described above, according to one aspect of the present invention, corrected velocities of blood flow can be displayed two- or three-dimensionally to provide information about the pulsatility in a steadier way with the artery, vein, portal vein and others distinguished one from another. Accordingly the visibility toward blood flows is greatly raised, both of efficiency and accuracy of diagnostic examinations are upgraded, thus leading to an improved diagnostic performance.
Furthermore, as another aspect of the present invention, a three-dimensional scan is performed to track the pulsatility of blood flow through three-dimensional display. In that case, the three-dimensional scan is carried out with one section scanned a plurality of times, so that three-dimensional pulsatile data is provided with higher precision, thereby leading to a greatly improved diagnostic performance.
The remaining features of the present invention will be clearly understood from the following description of preferred embodiments, which is described together with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGSIn the accompanying drawings:
FIGS. 4(a) and 4(b) are time-velocity charts depicting the operation of an instantaneous velocity extractor, in which
FIGS. 5(a) to 5(c) are views illustrating aliasing with the use of a vectorial mean value or its absolute value as a mean velocity data per a period of time of one heartbeat;
FIGS. 10(a) to 10(e) illustrate examples displaying color bars;
FIGS. 11(a) and 11(b) illustrate an artery displayed on a conventional velocity mode;
FIGS. 12(a) and 12(b) are views illustrating the display of the same artery as shown in
FIGS. 16(a) to 16(c) illustrate some examples of a volume scan;
FIGS. 17(a) to 17(c) illustrate other examples of the volume scan;
FIGS. 18(a) to 18(c) are examples of control sequences for the volume scan;
FIGS. 19(a) to 19(c) are illustrations of an electronic scan with the use of a two-dimensional array probe, which is written in comparison with other scan methods;
FIGS. 22(a) and 22(b) are views illustrating display examples of three-dimensional images;
FIGS. 25(a) to 25(c) are various charts indicating temporal changes in velocities at a pixel pointed by a marker;
FIGS. 30(a) to 30(d) are views exemplifying display of both the pulsatility and power in a mixed manner.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTSWith reference to the accompanying drawings, embodiments of an ultrasonic diagnosis apparatus in which the present invention is implemented will now be described in detail.
First EmbodimentAn ultrasonic diagnosis apparatus according to a first embodiment of the present invention will now be described with reference to FIGS. 1 to 14.
The probe 1 includes a function of two-way conversion between an ultrasound signal and an electric signal. One example of the probe 1 is configured such that an array type of piezoelectric transducer is linearly set in an array at the distal part of the probe. This array type of piezoelectric transducer is composed of a plurality of piezoelectric elements arrayed in parallel, in which its arrangement direction is assigned to a scan direction. Each of the plurality of piezoelectric elements forms each channel for transmission and reception (i.e., called transmission channel and reception channel).
The transmitter 2, as shown in
The receiver 3, as shown in
The I and Q signals thus generated make a directional separation of a Doppler signal possible. That is, those signals can be used to determine whether a moving element such as blood flow approaching to the probe 1 or going away from the probe 1. The I and Q signals (hereinafter simply referred as a “Doppler signal”) are transmitted to the CFM processor 4 and the tomographic image processor 5, respectively.
The tomographic image processor 5 produces tomographic image data of the subject as a B-mode tomographic image from the received signals obtained through the transmission and reception of ultrasound pulses. The produced tomographic image data are sent to the display unit 6.
The CFM processor 4, as shown in
In this CFM processor 4, the moving-element signal extractor 41 acquires a blood-flow Doppler signal by removing a clatter component signal from the echo signal, and then the blood-flow Doppler signal is sent to the velocity corrector 42. In the velocity corrector 42, the pulsation-characterizing velocity calculators 43 calculates, as a velocity of a moving element based on the present invention, a velocity indicating characteristics of the pulsation, while the representative velocity calculator 44 calculates a representative velocity serving as a reference velocity. In addition, the corrector 45 corrects the velocity indicating characteristics of the pulsation with the use of the representative velocity, so that data of a corrected velocity is produced, and sent to the display unit 6.
The display unit 6 is configured to produce image data in which, for example, image data of CFM blood-flow corrected velocities from the CFM processor 4 are overlaid on tomographic image data from the tomographic image processor 5 and data of a color bar or others showing the amplitude of the corrected velocities are placed thereon. The produced image data is displayed on a monitor. Thus, the corrected velocity data is mapped for display on the monitor, so that the pulsatility can be visualized in an easy and simple way without failure. Blood vessels, such as an artery, portal vein, or vein, can be distinctively displayed, with the result that visibility for various types of blood vessel becomes higher, thus improving a diagnostic performance.
The velocity corrector 42 according to the present invention will now be exemplified in detail.
In this configuration, a blood-flow Doppler signal at each pixel, which is outputted from the moving-element signal extractor 41 (hereafter this expression will be omitted since the following is concerning the calculation per pixel) is sent to the velocity corrector 42A. In the velocity corrector 42A, velocity data are calculated from the blood-flow Doppler signal at the velocity calculator 46, and the velocity data that has been calculated are temporarily stored in the buffer memory 47.
Velocity data calculated during a period of time of one heartbeat or its equivalent time (hereafter called “one heartbeat time”) is stored in the buffer memory 47. Whenever new velocity data comes from the velocity calculator 46, the oldest data in the buffer memory 47 is removed. Hence, in the buffer memory 47, the velocity data is updated in real time, while velocity data acquired during a period of one heartbeat time is held at any time.
Concurrently with the above data update, the pulsation-characterizing velocity calculator 43 operates to obtain a velocity Vcha indicating a specified characteristic of the pulsation by extracting it from velocity data acquired during one heartbeat period stored in the buffer memory 47 or from a related group of velocities. The resultant velocity Vcha is sent to the corrector 45.
Meanwhile, the representative velocity calculator 44 calculates a representative velocity Vrep from velocity data acquired during one heartbeat time in the buffer memory 47, and send the velocity Vrep to the corrector 45.
The corrector 45 engages in correcting the velocity Vcha indicating the specified characteristic of the pulsation by using the representative velocity Vrep, providing a corrected velocity Vcmp. The corrected velocity Vcmp is expressed by:
Vcmp=G(Vcha, Vrep),
where G is a function for the correction. The thus-corrected velocity Vcmp is outputted to the display unit 6.
Since the velocity corrector 42 provides the representative velocity Vrep every one-heartbeat time, the representative velocity Vrep is hardly disturbed by heartbeats. Hence the corrected velocity Vcmp in which the nature of the pulsation-characterizing velocity Vcha is accurately reflected can be obtained.
In the present embodiment, in response to each time of update on newly inputted velocity data in the buffer memory 47, the velocity Vcha indicating a characteristic of the pulsation and the representative velocity Vrep are also recalculated for the next update every time new velocity data is received. Consequently, the corrected velocity Vcmp is also subjected to recalculation for the next update responsively to the reception of new velocity data. It is therefore possible for the velocity corrector 42 to output the corrected velocity Vcmp in real time. The corrected velocity data is thus excellent in the real-time performance.
One heartbeat time in the present embodiment is set to both of the buffer memory 47 and the representative velocity calculator 44 by the one-heartbeat-time setting unit 48. Specifically, the number L of samples obtained during one heartbeat time is set. The number L is obtained by dividing a period of time THR equivalent to one heartbeat by a sampling time TFR for velocity data. The sampling time shows intervals of time at each of which velocity data is updated, that is, corresponds to a reciprocal number of the number of frames.
Therefore, the calculating equation of the number L of samples is as follows:
L=THR/TFR.
Concerning this equation, a period of time THR corresponding to one heartbeat time is obtained by measuring a period of time of one heartbeat based on an electrocardiographic gating signal obtained from a subject with the use of electrocardiographic gating circuit not shown in
While the present embodiment has been described based on one heartbeat, the present invention is not limited to such a case, but may use a plurality of heartbeats. In the case of a plurality of heartbeats, the time THR is basically interpreted as being merely repetitions of that obtained in the case of one heartbeat. However, both a velocity indicating the characteristics of the pulsation and a representative velocity are usually unchanged from those values obtained during one heartbeat, thus requiring a larger capacity of the buffer memory 47 if a plurality of heartbeats are employed. Accordingly, it is preferable to use one heartbeat. It is also possible to use an approximate value, which is obtained through averaging based on a shorter period of time less than a period of time of one heartbeat, thus requiring a smaller capacity of the buffer memory 47. In general, it is sufficient if a period of time equal in effect to a mean over a period of time of one heartbeat.
FIGS. 4(a) and 4(b), which illustrate the operation of the instantaneous velocity extractor 43A in the above configuration, are charts depicting a change in velocity V per time t at a certain one pixel constituting an image (hereafter, all charts to FIGS. 4(a) and 4(b) are shown at one pixel).
In
More specifically, in the data group (1), the oldest data in the data group (0), i.e., V1 is cleared and the latest data, i.e., VL+1 is added. The data in the buffer memory 47 are updated in this way in turn.
In
Meanwhile, in the mean velocity calculator 44A, a mean value <V> of velocity data over a period of time of one heartbeat is calculated. The mean value <V> can be determined as being any of an mean value of velocities V1, V2, . . . , VL obtained at each time phase, the absolute value of a mean value of velocities V1, V2, . . . , VL obtained at each time phase, the mean value of an absolute value of velocities V1, V2, . . . , VL obtained at each time phase, and an RSM value (Real Mean Square Value) of velocities V1, V2, . . . , VL obtained at each time phase. Therefore, an equation for calculating a mean value <V> can be determined from the following equations:
<V>=(V1+V2+ . . . +VL)/L
<V>=|V1+V2+ . . . +VL|/L
<V>=(|V1|+|V2|+ . . . +|VL|)/L
<V>=SQRT{(V12+V22+ . . . +VL2)/L}.
In the above equations, L is the number of samples of velocity data over a period of time of one heartbeat at each pixel.
Alternatively, the mean value <V> may be decided as being a value or its absolute value, which is calculated by applying an FIR filter, IIR filter, or nonlinear filter to velocities V1, V2, . . . , VL obtained at each time phase or their absolute values |V1|, |V2|, . . . , |VL|. If defining a function FIL required for the filtering calculation, equations for the mean value <V> may be exemplified as follows:
<V>=FIL (V1+V2+ . . . +VL)
<V>=|FIL (V1+V2+ . . . +VL)|
<V>=FIL (|V1|+|V2|+ . . . +|VL|)
<V>=|FIL (|V1|+|V2|+ . . . +|VL|).
Furthermore, a vectorial mean value or its absolute value of velocities V1, V2, . . . , VL obtained at each time phase may be set to the mean value <V>. Embodiments of this setting will now be described with the reference of FIGS. 5(a), 5(b) and 5(c).
FIGS. 5(a) to 5(c) illustrate aliasing of the Doppler velocity derived by the sampling theorem. In general, an ultrasound pulse is transmitted at predetermined intervals Trn, a blood flow Doppler signal to be acquired is formed into a discrete signal consisting of N-pieces of signals that should be mapped at constant intervals Trn, if considering one raster. Hence, as shown in
Accordingly, in the case of
Therefore, as shown in FIG.5(c), a mean of velocities V1, V2, . . . VL obtained at each time phase can be obtained by adding or averaging complex autocorrelation functions Z1, Z2, . . . , ZL for each time phase on the same complex plane. This averaging technique can be understood as a vectorial averaging technique. This averaging is advantageous in that it will not be influenced by aliasing, unless the velocity changes extremely.
Another method of obtaining a mean of autocorrelation functions is that the amplitudes of autocorrelation functions Z are subject to normalization before averaging them. A mean <Z>may be calculated with the use of one of the equations:
<Z>=(Z1+Z2+ . . . +ZL)/L
<Z>=(Z1/|Z1|+Z2/|Z2|+ . . . +ZL/|ZL|)/L.
(For example, in the case of
Since the thus-obtained mean <Z> of the autocorrelation functions is expressed as being <Z>=<X>+j<Y>, a mean <V> of the velocities V may be calculated by the following equations, if the previously defined equations (2) and (4) in the section of the background of the invention are employed:
<V>=c/(2fM)·(2πTrn)−1 tan −1 (<Y>/<X>)
<V>=|c/(2fM)·(2πTrn)−1 tan −1 (<Y>/<X>)|.
Concerning the embodiment shown in FIG.3, the above calculation is implemented by storing autocorrelation functions Z1, Z2, . . . , which are outputted from the velocity calculator 46, into the buffer memory 47 and by sequentially reading out the autocorrelation functions Z1, Z2, . . . stored in the buffer memory 47 into the mean velocity calculator 44A. This allows the mean velocity calculator 44A to calculate mean values <V0>, <V1>, . . . of velocity data included in each of the data groups (0), (1), . . . in turn. Then the divider 45A is allowed to calculate corrected velocity Vcmp0, Vcmp1, . . . in turn on the basis of the equations expressed as follows:
Vcmp0=VL/<V>0
Vcmp1=VL+1/<V>1
. . . .
In these equations, in lieu of the mean values <V0>, <V1> of the velocity data which are employed as the denominators, adopting an absolute values of each of the mean values, the corrected velocities Vcmp0, Vcmp1, . . . are calculated based on the equations expressed as follows:
Vcmp0=VL/|<V>0|
Vcmp1=VL+1/|<V>1|
. . . .
The foregoing equations for the corrected velocities provide corrected velocity data with orientation, which has undergone the directional separation by means of the plus or minus sign of an instantaneous velocity appearing as a numerator.
Similarly, in lieu of the corrected velocities Vcmp0, Vcmp1, the absolute value of each of the velocities Vcmp0, Vcmp1, . . . can be adopted based on the equations expressed as follows:
Vcmp0=|VL/<V>0|
Vcmp1=|VL+1/<V>1|
. . . ,
thus providing the corrected data which indicate their magnitudes only.
In addition, an instantaneous velocity to be sampled is not limited to the latest velocity as described before, but any of data stored in the buffer memory 47 may be usable.
In the foregoing case of
Although the velocity corrector 42B shown in
Specifically, in the case of a calculation technique according to the embodiment in FIG.6, a value ζ<V> derived by multiplying a mean velocity <V> by a certain constant ζ corresponds to a display range (ζ is a constant independent of the pixels). In addition, a mean velocity <V> which differ from each other pixel by pixel is multiplied by a constant ζ to produce a velocity range ζ<V> which differs from pixel to pixel. Then an instantaneous velocity V at each pixel is divided by the velocity range ζ<V> at each pixel. However, in general, the mean velocity/reference velocity converter 45B operates to covert the instantaneous velocity V into an amount specific to the velocity range ζ<V> for velocity correction. This correcting example yields a difference in velocity, which is ζ (a constant) times larger than a velocity corrected by the foregoing dividing technique, but such a difference can be eliminated when being allocated to gradations of a color bar later described.
Since the corrected velocity is originated from a detected velocity, the calculation of a velocity for characterizing characteristics of the pulsation and the calculation of a representative velocity are influenced by aliasing. This aliasing arises theoretically based on the sampling principle. It is therefore impossible to erase its effect completely, but the aliasing can be corrected. One correction technique is the foregoing vectorial calculation, while there are some other correction techniques, which will be described below.
Based on the above principle, the aliasing is corrected by-the aliasing corrector 49. This correction of the aliasing enables a more broadened range of detectable velocities, improving accuracy of velocity to be measured. Accordingly, the detectability for the pulsatility can be enhanced, and a diagnostic performance is also more improved.
The corrected velocity calculated as above is displayed on a screen of the display unit 6. One display example is illustrated in
As shown in
Hence, it is preferable that a corrected velocity less in amplitude than the mean velocity “1” or thereabouts is displayed in red or reddish hues. In contrast, as a corrected velocity increases gradually larger in amplitude than the mean velocity “1” or thereabouts, the display is made to move from yellowish hues to yellow. Such a display manner is exemplified as shown in
In this way, the colors assigned to the color bar is decided depending on whether or not a corrected velocity is smaller in amplitude than the mean velocity “1” or thereabouts. When the corrected velocity is higher in amplitude than this threshold, a certain hue and its related hues showing higher velocities are used. When the opposite case to the above comes true, another hue and its related hues showing lower velocities are used. It is thus possible to distinguishably assign the hues to both of the non-pulsatility and pulsatility, thereby providing a visibly easier distinction to pulsated states, thereby contributing to improvement in diagnosis.
FIGS. 10(a) to 10(e) illustrate examples of color bars that can be displayed.
By the way, the present embodiment has adopted the correction of aliasing of velocities, but it is still impossible to correct the aliasing perfectly. It is therefore better for an operator to cope with such an imperfect corrected state of the aliasing on the monitor of the display unit 6. To realize this assist, aliasing velocities providing a region of velocities defined by the sampling principle are depicted on the monitor.
For example, as previously described
Since it is usual that an operator knows an approximate detectable velocity range, the operator may additionally adjust the aliasing velocity by operating a not-shown button on an operation panel. The aliasing can therefore be avoided with higher precision. Hence, images that are more suitable to higher accurate diagnosis can be obtained.
Further, since the pulsatility is originated from the pumping action of the heart, its characteristic aspect is typically seen during an ejection period of one cardiac cycle. That is, as described before, while the velocity of blood flow through veins and portal veins is almost even throughout one cardiac cycle, the velocity of blood flow through arteries rapidly increases in the ejection period, and then gradually decreases until the next ejection period. For detecting the pulsatility, therefore, it is essential to track the ejection period with certainty. For this purpose, it is preferable that a cross section of a subject is scanned at the number of frames higher than a reciprocal number of a period of time equal to the ejection period of the heartbeat. This way of scanning enables the ejection period to be tracked without failure, thus the pulsatility being depicted more certainly.
The effect obtained from the display of corrected velocities according to the present embodiment will now be described in comparison with that of the conventional one.
FIGS. 11(a) and 11(b) illustrate the display of an artery depicted on the conventional velocity mode.
Practically, as shown in FIGS. 11(a) and 11(b), at such positions as a narrow vessel of which blood velocity is slower (for example, at the position β) or a vessel of which Doppler angle is larger (for example, at the position γ), the resultant pulsatility is depicted smaller than it is originally. Therefore, it is actually difficult that the pulsatility at those points is distinguished visually from blood vessels that exhibit a weaker pulsatility. In addition, a color bar is displayed which depicts velocities, for example, in gradually changing hues from “velocity zero” to positive and negative aliasing velocities. This results in that the position α is visualized using a hue showing a faster velocity and the positions β and γ are visualized using other hues showing a slower velocity, making the discrimination of blood vessels more difficult. On top of it, the range displayed by the color bar and/or how to display on the color bar are not always suitable for the display of the pulsatility and the display itself on the color bar is difficult to understand when viewed. Under such circumstances, it was not easier to correctly interpret the pulsatility on the conventional velocity mode.
On the other hand, FIGS. 12(a) and 12(b) illustrate the display of corrected velocities according to the present invention, which track and depict the same artery as that shown on the conventional (shown in FIGS. 11(a) and 11(b)).
As shown in FIGS. 12(a) and 12(b), all the corrected velocities are nearly the same, as long as the same vessel is concerned. In other words, all of a thinner and smaller-Doppler-angle portion (like the position α), a thinner portion (like the position β), and a larger-Doppler-angle portion (like the position γ) provides the same behavior in corrected velocities. That is, the corrected velocities can be nearly “1” in their gradually-decreasing ranges and nearly the same value larger than “1” in their strongly pulsated ranges.
It can therefore be concluded that the velocity mode of the present embodiment is independent on flow velocities and Doppler angles, thus providing approximately equal corrected velocities, thus depicting almost the same pulsatility, as long as the same vessel is subjected to display. When such corrected velocities are subjected to the display with the use of the foregoing color bars, the display is independent on velocities and Doppler angles, thus the pulsatility being depicted clearly with largely improved visibility. In particular, under the velocity display mode according to the present embodiment, the pulsatility can be detected even for blood flows, such as blood flows whose velocities are slower, which are therefore sometimes difficult to be distinguished from non-pulsated vessels, or another blood flow subjected to larger Doppler angles. This is able to give images an effective depiction, thus contributing to greatly improved diagnosis.
Besides, as described above, a larger change in the pulsatility appears during the ejection period lasting 200 to 300 ms at most. Hence, it may feel short for a viewer when visually observing the pulsatility as it is displayed. In such a case, as exemplified in FIGS. 13(a) through 13(c), moderating changes in corrected velocities is effective for making visual observation easier.
FIGS. 13(a) and 13(b) exemplify temporal changes in corrected velocities with no velocity moderation and with velocity moderation, respectively. In this example, to steadily understand the pulsatility from the corrected velocities shown in
Such moderation processing can be performed by, for instance, the foregoing display unit 6. For realizing the moderation, the display unit 6 is configured as exemplified in
In this configuration, the corrected velocity data transmitted from the foregoing CFM processor 4 is temporarily stored in the color image memory 61. A plurality of frames of data is thus stored in the color image memory 61. The corrected-velocity-change moderator 60 reads out data from the color image memory 61 to conduct the above-mentioned moderation processing, and output resultant data to the DSC 63. Apart from this, the tomographic image data transmitted from the foregoing tomographic image processor 5 is stored in the tomographic image memory 62, before being outputted to the DSC 63.
In the DSC 63, in addition to predetermined image processing, raster conversion and other types of processing, a corrected-velocity image that have experienced the moderation processing in the corrected-velocity-change moderator 60 is overlaid on a topographic image from the tomographic image memory 62. The resultant image data is then sent to the monitor 64 so that an synthesized image is depicted thereon.
In addition, the present embodiment has adopted the CFM processor 4 that has the function of correcting velocities of blood-flow Doppler signals. An alternative is that such function is given to for example the display unit 6, of which configuration is shown in
The configuration shown in
Referring to FIGS. 15 to 22, a second embodiment of the ultrasonic diagnosis apparatus according to the present invention will now be described. The present embodiment concerns a configuration in which the correction of the foregoing blood-flow Doppler signals is applied to three-dimensional display.
As the remaining constituents, the ultrasonic diagnosis apparatus includes, as shown in
The two-dimensional array probe 7 has a function of two-way conversion between ultrasound signals and electric signal. To be specific, the probe 7 has a two-dimensional array type of piezoelectric transducer two-dimensionally placed at the tip. The a two-dimensional array type of piezoelectric transducer is formed by mapping a plurality of piezoelectric elements two-dimensionally, that is, like a matrix, so that a ultrasound beam signal can be scanned three-dimensionally, including the longitudinal, lateral, and oblique directions. A plurality of piezoelectric elements constitute transmitting and reception channels, respectively.
Hence, the two-dimensional array probe 7 is allowed to scan a plurality of sections located within a subject, as sections to be scanned are changed (i.e., a “volume scan” is performed), with the result that three-dimensional data (i.e., volume data) can be acquired. The volume scan is exemplified as various forms, as shown in FIGS. 16(a) to 16(c) and FIGS. 17(a) to 17(c).
One scanning example is shown in FIGS. 16(b) and 17(b), respectively, wherein an ultrasound beam scans a certain section during a period of one heartbeat, and then the ultrasound beam is shifted by a width equal to a beam thickness to scan the next section in the same manner. Another scanning example is shown in FIGS. 16(c) and 17(c), respectively, wherein an ultrasound beam scans a certain section for one frame of data, and then the beam is shifted slightly by a width smaller than a beam thickness to san the next section for one frame of data in the same manner as above. Either scanning technique permits any location, which is arbitrarily selected in the scanned three-dimensional space, to be scanned during a period of one heartbeat. This volume scan makes it possible ultimately to calculate corrected velocities in each section, thus making it possible ultimately to display the pulsatility in the three-dimensional manner.
The scanning techniques shown in FIGS. 16(b) and 17(b) are superior in respect of accuracy for calculating corrected velocities, since each section to be scanned is stationary during a period of one heartbeat. On the other hand, the techniques shown in FIGS. 16(c) and 17(c) are advantageous in that corrected velocities can be calculated specially with fineness, because sections to be scanned are consecutively located.
The scan controller 23 of the transmitter 2A (refer to
Of these,
In contrast, FIGS. 18(b) and 18(c) explain examples of scan sequences directed to the volume scan performed with the aid of the two-dimensional array type of probe according to the present embodiment.
Of these examples, the sequence exemplified in
In addition, the sequence exemplified in
For performing the volume scan, a parallel simultaneous reception technique may be used which enables simultaneous reception along a plurality of directions in response to one time of transmission for scanning a section. For instance, this technique can be applied to simultaneous scans toward a plurality of sections, providing various advantages including a shortened time for scanning a volume region. As long as each section is scanned during a period of time for one heartbeat, the parallel simultaneous reception technique can be implemented into various types of scanning techniques.
Because exemplified in the present embodiment is an electronic scan that uses the two-dimensional array probe 7, advantages derived therefrom will now be explained compared to the other scanning methods (that use a one-dimensional array type of probe).
Further,
In contrast,
Based on the data acquired by the two-dimensional array type of probe 7, velocities are corrected. For example, maximum velocities can be employed as the corrected velocities, whereby it is easier to perform three-dimensional reconstruction. The velocity corrector 42 responsible for the foregoing correction based on the maximum velocities is exemplified in its construction in
A velocity corrector 42E shown in
In the similar way to that in FIGS. 4(a) and 4(b), changes in velocity V over time t at a certain one pixel are shown in
In buffer memory 47, the data update is carried out in such that the oldest data in the data group, that is, velocity data V1, is removed, while the latest data, that is, VL+1, is added. This updating technique is repeated at intervals in turn.
In response to the operations in the buffer memory 47, the maximum velocity detector 43B operates to read out a maximum velocity from each of the groups of velocity data. Practically, in the case of the example shown in
In parallel, as described before, the mean velocity calculator 44A is engaged in the consecutive calculation of each mean value <V>0 (<V>1, <V>3, <V>4, . . . ) of each of the groups of velocities, whereby the resultant values are routed to the divider 45A.
Thus, the divider 45A receives both of a maximum velocity VI (VII, and others) from the maximum velocity detector 43B and a mean velocity <V>0 (<V>1, <V>3, <V>4, and others) from the mean velocity calculator 44A, and then calculates consecutively a corrected velocity Vcmp0 (Vcmp1, Vcmp2, Vcmp3, and others) using themes values that have been received, on the basis of the equations expressed as follows:
Vcmp0=VI/<V>0
Vcmp1=VI/<V>1
Vcmp2=VII/<V>2
Vcmp3=VII/<V>3
. . . .
In these equations, in lieu of mean velocities that are the denominators, the absolute values of the mean velocities may be adopted, whereby the corrected velocities can be calculated on the following equations.
Vcmp0=VI/|<V>0|
Vcmp1=VI/|<V>1|
Vcmp2=VII/|<V>2|
Vcmp3=VII/|<V>3|
Thus, the data of corrected velocities that have been oriented can be obtained, where each of which is directionally separated on the positive and negative signs of instantaneous velocities that are numerators.
In addition, corrected velocities may be obtained as their absolute values by the following equations:
Vcmp0=|VI/<V>0|
Vcmp1=|VI/<V>1|
Vcmp2=|VII/<V>2|
Vcmp3=|VII/<V>3|
so that the obtained values indicate only magnitudes of the corrected velocities. This calculation is identical to that previously shown on
This calculation enables the display of only maximum velocities that have been corrected. For instance, when applied to the foregoing example shown in
The maximum velocities that have been corrected are constantly updated in real time, without being frozen. Thus, even if a blood vessel is slightly moved in the subject's body due to, for example, a soft breathing, the blood vessel on an image can also be moved and depicted, still providing effective information that tracks the vessel. Accordingly, using such maximum velocity data that has been corrected makes it possible to provide pulsatile images that are excellent in visibility, preservation, and real-time performance, and suitable for constituting three-dimensional images. As a result, a diagnostic performance can be improved further.
The data of corrected velocities calculated by the velocity corrector 42E is then sent to the display unit 8, as described before (refer to
When the foregoing volume scan to acquire volume data is completed, the three-dimensional data of corrected velocities stored in the three-dimensional color image memory 81 and the two-dimensional or thee-dimensional tomographic image data stored in the three-dimensional tomographic image memory 82 are both read out. The read-out data are then subject to display processing according to a format specified and inputted by an operator through a not-shown operation panel, with the result that a three-dimensional image is depicted on the monitor 84 in cooperation with the DSC 83. Examples of display of such three-dimensional images are shown in FIGS. 22(a) and 22(b).
Accordingly, the above characteristics of image display can be applied to proper use originated from necessity. A pulsating vessel can therefore be displayed three-dimensionally, during which time a user is allowed to identify a desired position or observe a lesion on a topographic image. This makes it possible that both of the artery and the vein are observed with improved vessel continuity, greater visibility, convenience, and clearer distinction, whereby the efficiency and accuracy of each examination can be improved to a greater extent.
As explained above, the foregoing first and second embodiments permit the pulsation of blood vessels to be tracked, thus being in principle depicted distinguishably between the artery and the vein. However, it is clear that there is no one-to-one correspondence as to the pulsatility between the artery and vein, and it is conceivable that some exceptions may occur.
For example, an inferior vena cava indicates to some extent the pulsatility. In such a case, even a vein may provide an image in which the pulsatility appears to a small extent. In contrast, a Doppler image shown in
Countermeasures for improving the above situation will now be described on examples preferably shown in
In the case of such examples, first of all, the calculation for velocity at individual pixels is carried out by the CFM processor to obtain velocities at the pixels, like the conventional. Then, as shown in
This display technique allows spectrum Doppler data to be obtained from the same scanned data as those used for display the pulsatility, thus preventing the number of frames from being lowered. In contrast, the conventional parallel display of CFM images and spectrum Doppler data require to be scanned separately and dedicatedly from each other, resulting in that the number of frames which can be used for CFM images is decreased down to half of the frames. The advantage of keeping the number of frames, which can be obtained by the present embodiment, is thus strictly significant if it is desired that an ejection period be securely tracked for displaying the pulsatility. Moreover, another advantage of the present embodiment is that temporal changes in velocities detected at a plurality of positions are displayable, although the conventional parallel display of CFM images and spectrum Doppler data allows Doppler spectrum data to be displayed at only one position. Thus, the present embodiment is able to provide a remarkably improved usage. Of course, in the present embodiment, Doppler spectrum data at a plurality of positions can be displayed in real time in synchronism with displaying pulsatile images. Additionally, only a chart showing velocities versus time or only pulsatile images can be frozen.
A modification is that a marker used in the present embodiment is variable in its size. Thus, spatial averaging of data enclosed by the size-changeable marker is able to stabilize velocity data that will be produced. In the present embodiment, plotting a velocity at each frame forms charts showing the relationship between velocities versus time, which are exemplified in FIGS. 25(a) to 25(b). As shown therein, how to plot velocities can be changed. For instance, a velocity obtained at each frame is plotted with the use of a dot. Alternatively, such dots can be connected with polygonal lines or a curved line. Another modification is that an electrocardiographic gating technique is used to obtain velocities as the cardiac time phase is shifted gradually and velocities obtained during several heartbeats are overlaid one on another, thus providing a chart with closer intervals of time. Still, another modification is concerned with the calculation of velocities, in which a mean velocity at each pixel, which is usually obtained for only the display, is combined with the dispersion of a velocity at the pixel, in order to obtain a pseudo maximum velocity for display. Moreover, the foregoing embodiment is suitable for real-time display, but this is not a definite list. By way of example, the display of the pulsatility may be frozen, before a velocity-time chart at a specified pixel is displayed, if velocity data is once stored in a memory.
The above various modifications will upgrade images that depict pulsatile flows, making it possible to detect pulsatility in a more sure fashion, thus further improving a diagnostic performance.
The foregoing pulsatile flow display can be applied to the following first to third examples.
1) The first application example is concerned with combining the foregoing pulsatile flow display with a known broad-band transmission technique (refer to, for example, Japanese Patent Laid-open (KOKAI) publications Nos. 2000-342586 and 2001-269344). This “broad-band transmission” technique, which is carried out under the power Doppler mode, is a way of transmitting an ultrasound pulse consisting of one or two burst waves, instead of transmitting an ultrasound pulse consisting of four to eight burst waves. The one or two burst waves are equivalent in the number of burst waves to that under the B-mode, thus providing a broad-band ultrasound pulse. This “broad-band transmission” technique is able to provide range discrimination essentially equivalent to the B-mode (for example, refer to a Japanese Patent Laid-open (KOKAI) Publication No.2000-342586).
One example of the broad-band ultrasound pulse is an ultrasound pulse of which number of burst waves is less than three. By using this ultrasound pulse, it becomes possible to obtain blood flow images of high spatial resolution with no or almost no blooming, so that diagnostic performance is further improved (refer to a Japanese Patent Laid-open (KOKAI) Publication No. 2000-342586, for example). Computing the reciprocal number of a transmission frequency of a transmission ultrasound pulse produces one cycle of the transmission pulse. An ultrasound pulse of which duration is equal to one cycle of a transmission pulse is called a “pulse of one burst wave” and an ultrasound pulse of which duration is equal to two cycles of a transmission pulse is called a “pulse of two burst waves.” Thus, an ultrasound pulse of which duration is equal to M-cycles of a transmission pulse is called a “pulse of M-piece burst waves.” One burst waves, two burst waves, . . . , M-piece burst waves are called the number of burst waves.
Accordingly, the present application example will provide a further improved resolution performance, in addition to the effects derived from the foregoing pulsatile flow display.
2) The second application example concerns an improved way of calculating the foregoing reference velocity.
In addition to the foregoing one-time averaging technique, a two-time averaging technique can be provided as the technique for calculating a mean according to the present application example, which is shown in
This two-time averaging technique is advantages as follows. 1) In the artery shown in
3) The third application example is directed to a display mode, in which both of the foregoing pulsatile flow display and a known power display are carried out by mixture.
In the case that an organ is moved by breathing, heartbeats, or others, or a blood vessel to be observed is a peripheral blood vessel or a blood vessel with the large Doppler angle, it happens that the blood flow signal may not be detected temporarily or at some cardiac time phases. Resultantly, the reference velocity may not be determined, which make it impossible to correct velocities of a moving element.
To be specific, in cases where an organ moves, any one pixel on a blood vessel may not be present at the same location during one heartbeat time. Hence, all the velocity data of a moving element which should be gathered during one heartbeat time are not always fully acquired, thereby lacking data.
In addition, in the case of a peripheral blood vessel, a velocity of blood is slow, so that a possible Doppler signal frequency to be detected becomes lower. In the case of a blood vessel having a larger Doppler angle, a Doppler signal frequency to be detected is also obliged to be lower due to its angle dependency. In such cases, an MTI filter operates to eliminate a signal of which Doppler frequency is lower. This means that, for example, it is possible to detect Doppler signals during an ejection period at the artery, while it is difficult to fully detect Doppler signals during a diastole thereat. If such an occasion occurs, it is impossible to prepare for all velocity data of a moving element during one heartbeat time, thus lacking data.
The present application example is to cope with such a situation. For this purpose, this example is configured such that the reference velocity can be determined even when velocity data of a moving element lacks to some extent. Hereinafter, this will be described about one pixel on an image.
As shown in
In contrast, if velocities of a moving element can be detected only in frames less than 14 frames among the 20 frames, the determination can be made such that a reference velocity calculated on velocity data of those frames is unreliable. If such a determination can be done, a reference velocity will not be calculated, thus the velocity correction being not performed (refer to (4) in
As a result of it, as shown in
In this pulsatile flow/power mix display mode, for enhanced visibility, it is preferred that a pulsatile flow image and a power image are both depicted in colors. Color bars for such display are exemplified in FIGS. 30(b) and 30(c), in which two color bars are placed together; one is for corrected velocities (i.e., for a pulsatile flow image) and the other is for a power image.
The example in
Furthermore, an upper limit and a lower limit accompany the color bar for corrected velocities shown in
In addition, as shown in
As has been described above, the present application examples are able to not only raise the detectability for blood flow and its pulsatility but also enhance the visibility for the pulsation. This is helpful for a greatly improved diagnostic performance.
The present invention is not limited to the foregoing embodiments that are typically shown and various modifications and alterations may occur to one skilled in the art based on contents written in the claims, without departing from the spirit of the present invention. These modifications and alterations pertain to the claim(s) of the present invention.
Claims
1. An ultrasonic diagnosis apparatus comprising:
- scanning means for scanning a subject to be examined while transmitting and receiving an ultrasound pulse to and from the subject;
- means for obtaining in sequence a plurality of velocities of a moving element within the subject based on reception signals acquired by the scanning performed by the scanning means;
- processing means for computing a reference velocity based on the plurality of velocities obtained from during a predetermined period of time and correcting each of the velocities of the moving element using the reference velocity so that data of the corrected velocities is obtained; and
- displaying means for displaying the data so that the data is updated a plurality of times during the predetermined period of time.
2. The ultrasonic diagnosis apparatus according to claim 1, wherein the reference velocity is at least one selected from
- 1) a mean of velocities acquired during a predetermined period of time or an absolute value of the mean thereof,
- 2) a mean of absolute values of velocities acquired during a predetermined period of time,
- 3) an RMS (Root Mean Squire Value) value of velocities acquired during a predetermined period of time,
- 4) a value or an absolute value thereof, which is calculated by applying any one of an FIR (Finite Impulse Response) filter, IIR (Infinite Impulse Response) filer, and a non-linear filter to velocities acquired during a predetermined period of time or absolute values of the velocities, and
- 5) a vectorial mean of velocities acquired from a predetermined period of time or an absolute value of the mean.
3. The ultrasonic diagnosis apparatus according to claim 1, wherein the processing means comprises at least one of
- 1) means for dividing the velocities of the moving element by the reference velocity, and
- 2) means for converting the velocities of the moving element to values relative to the reference velocity.
4. An ultrasonic diagnosis apparatus comprising:
- scanning means for scanning a subject to be examined while transmitting and receiving an ultrasound pulse to and from the subject;
- means for obtaining velocity information about a moving element within the subject based on reception signals acquired by the scanning performed by the scanning means;
- display image producing means for producing an image to be displayed indicative of a state of pulsation on the basis of the velocity information; and
- means for controlling the display image producing means so that display of the pulsation is switched on or off on the basis of the velocity information.
5. The ultrasonic diagnosis apparatus according to claim 1, wherein the processing means has at least one of means for correcting aliasing resultant from a sampling theorem for the velocities and means for moderating temporal changes in the data obtained by the processing means.
6. The ultrasonic diagnosis apparatus according to claim 1, wherein the scanning means is configured to scan one section of the subject at the number of frames larger than a value indicated by an inverse number of a period of time corresponding to an ejection period of cardiac pulsation.
7. The ultrasonic diagnosis apparatus according to claim 1, wherein the display means is configured to display a two-dimensional image of the data obtained by the processing means.
8. An ultrasonic diagnosis apparatus comprising:
- scanning means for three-dimensionally scanning one section of a subject to be examined a plurality of times corresponding to one heartbeat while transmitting and receiving an ultrasound pulse to and from the subject;
- means for obtaining in sequence velocities of a moving element within the subject based on reception signals obtained three-dimensionally by the scanning means;
- processing means for computing a reference velocity based on the plurality of velocities obtained from during a predetermined period of time and correcting each of the velocities of the moving element using the reference velocity so that data of the corrected velocities is obtained; and
- displaying means for displaying at least a three-dimensional image based on the data so that the image is updated a plurality of times during the predetermined period of time.
9. The ultrasonic diagnosis apparatus according to claim 8, wherein the scanning means is configured to three-dimensionally scan the subject through an electrical scan by means of a two-dimensional array type of transducer, the velocities of the moving element are set to a maximum velocity during a predetermined period of time, and the reference velocity is information that is unchangeable over cardiac time phases of the subject.
10. The ultrasonic diagnosis apparatus according to claim 8, further comprising means for obtaining a tomographic image of the section,
- wherein the display means has at least one of means for displaying on the same monitor the tomographic image and the image of data obtained by the processing means and means for displaying on the tomographic image the image of data obtained by the processing means in a superposition manner, the tomographic image being a two-dimensional image and a three-dimensional image.
11. The ultrasonic diagnosis apparatus according to either of claim 1 or 8, further comprising at least one of
- means for displaying in colors the image of data obtained by the processing means,
- means for displaying pieces of information formed by combining the data obtained by the processing means and power information of scattering echoes from the moving element within the subject,
- means for displaying a color bar mapped not only by a hue indicative of a lower velocity when magnitudes of the data obtained by the processing means are nearly equal to or less than the reference velocity but also by other hues indicative of higher velocities as the magnitude of the data obtained by the processing means becomes larger than a value nearly equal to the reference velocity, and
- means for displaying together both of the data obtained by the processing means and an aliasing velocity.
12. The ultrasonic diagnosis apparatus according to either of claim 1 or 8, wherein the processing means includes means for obtaining the velocities of the moving element within the subject pixel by pixel, the apparatus further comprising means for displaying together both of a graph showing temporal changes in the velocities at one or more of the pixels and the image of the data obtained by the processing means.
13. The ultrasonic diagnosis apparatus according to claim 8, wherein the processing means comprises processing means for obtaining factors including a pulsatility index (PI) and a resistivity index (RI).
14. The ultrasonic diagnosis apparatus according to either of claim 1 or 8, further comprising at least one of
- means for displaying by mixture the image of the data obtained by the processing means and an information of power information of scattering echoes from the moving element within the subject,
- means for displaying by mixture an image of the power information and an image of information formed by combining the data obtained by the processing means and the power information,
- means for displaying together both of a color bar for the data obtained by the processing means and another color bar for the power information,
- means for displaying together both of a color bar indicative of a combination of the data obtained by the processing means and the power information and another color bar for the power information,
- means for setting an upper limit and a lower limit on the color bar for the data obtained by the processing means, and
- means for displaying at least one of an upper limit, a lower limit, and an aliasing velocity on the color bar for the data obtained by the processing means.
15. The ultrasonic diagnosis apparatus according to claim 2, further comprising means for re-averaging velocities of the moving element which are equal to or smaller than a value produced by multiplying the average by “1+α” (α≧0) after the average and for setting to the reference velocity another mean obtained by the re-averaging.
Type: Application
Filed: Feb 17, 2006
Publication Date: Aug 17, 2006
Applicant: KABUSHIKI KAISHA TOSHIBA (Tokyo)
Inventor: Eiichi Shiki (Otawara-Shi)
Application Number: 11/356,263
International Classification: A61B 8/06 (20060101);