CROSS-REFERENCE TO RELATED APPLICATIONS This application is a continuation of U.S. application Ser. No. 12/652,537, filed Jan. 5, 2010, which is a continuation of U.S. application Ser. No. 11/434,711, filed May 15, 2006 (now U.S. Pat. No. 7,666,596), which claims priority from U.S. Provisional Application Ser. No. 60/683,737, filed May 23, 2005. The disclosures of the prior applications are considered part of (and are incorporated by reference in) the disclosure of this application.
TECHNICAL FIELD This document relates to methods and materials involved in tissue rejection (e.g., organ rejection) and detecting tissue rejection.
BACKGROUND The transplantation of tissue from one mammal to another has been used for years to save lives and to improve the quality of lives. For example, the first successful kidney transplant was performed in the mid-1950s between identical twin brothers. Since then, donors have grown to include not only close relatives but also distant relatives, friends, and total strangers. In some cases, the recipient may reject the transplanted tissue. Thus, tissue rejection is a concern for any recipient of transplanted tissue. If a doctor is able to recognize early signs of tissue rejection, anti-rejection medication often can be used to reverse tissue rejection.
SUMMARY This document relates to methods and materials involved in detecting tissue rejection (e.g., organ rejection). More particularly, this document relates to methods and materials involved in the early detection of tissue rejection (e.g., kidney rejection) and the assessment of a mammal's probability of rejecting tissue such as a transplanted organ. For example, this document provides nucleic acid arrays that can be used to diagnose tissue rejection in a mammal. Such arrays can allow clinicians to diagnose tissue rejection early based on a determination of the expression levels of nucleic acids that are differentially expressed in tissue being rejected as compared to control tissue not being rejected. The differential expression of such nucleic acids can be detected in tissue being rejected prior to the emergence of visually-observable, histological signs of tissue rejection. Early diagnosis of patients rejecting transplanted tissue (e.g., a kidney) can help clinicians determine appropriate treatments for those patients. For example, a clinician who diagnoses a patient as rejecting transplanted tissue can treat that patient with medication that suppresses tissue rejection (e.g., immunosuppressants).
The description provided herein is based, in part, on the discovery of nucleic acids that are differentially expressed in tissue being rejected as compared to control tissue that is not being rejected. Such nucleic acids can be nucleic acids that are induced by, for example, gamma interferon (IFN-γ). The term “gamma interferon induced transcripts” or “GITs” as used herein refers to transcripts that are expressed in kidneys of mammals treated with IFN-γ at a level at least 2-fold greater than the level of expression in normal kidney tissue. In some embodiments, a “GIT” is identified based expression that is increased at least two-fold in response to IFN-γ in normal kidneys of one or more particular strains (e.g., B6, CBA, and/or BALB/c) as compared to the level of expression in untreated normal kidney. The term “rejection induced transcripts” or “RITs” as used herein refers to transcripts that are elevated at least 2-fold in WT kidney allografts at day 5 post transplant in WT hosts vs. normal kidneys. In some embodiments, a “RIT” is identified based on expression that is increased at least two-fold in WT allografts from one or more particular strains (e.g., B6, CBA, and/or BALB/c) as compared to the level of expression in normal kidney. The term “injury and repair-induced transcripts” or “IRITs” refers to transcripts that are increased at least two-fold in isografts at least once between day 1 and day 21, as compared to normal kidney, and also are increased at least two-fold in CBA allografts at day 5 as compared to normal kidneys.
The term “gamma interferon and rejection induced transcripts” or “GRITs” as used herein refers to IFN-γ and rejection-inducible transcripts. These transcripts are (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) expressed at levels at least 2-fold lower in kidney tissue from IFN-γ-deficient (GKO) D5 allografts as compared to WT D5 allografts. Thus, the expression of GRITs is affected by the presence or absence of IFN-γ in allografts. The term “GRIT-like” transcripts as used herein refers to transcripts that are (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) not lower or even increased when IFN-γ is absent in GKO D5 allografts compared to WT D5 allografts. GRIT-like transcripts, despite being inducible by rIFN-γ, are increased in allografts by mechanisms largely independent of IFN-γ.
The term “transcript” as used herein refers to an mRNA identified by one or more numbered Affymetrix probe sets, while a “unique transcript” is an mRNA identified by only one probe set. The term “true interferon gamma dependent and rejection-induced transcripts” or “tGRITs” refers to rejection-induced transcripts that are IFN-γ-dependent in rejection, and also are unique transcripts that are increased at least 2-fold by rIFN-γ. The term “occult interferon gamma dependent and rejection-induced transcripts” or “oGRITs” refers to GRITs that are unique transcripts, but that are not 2-fold induced by rIFN-γ in normal kidneys.
The description provided herein also is based, in part, on the discovery that the expression levels of RITs can be used to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected. For example, the expression levels of nucleic acids listed in Table 2, Table 7, and/or Table 11 can be assessed in transplanted tissue to determine whether or not that transplanted tissue is being rejected. In addition, the description provided herein is based, in part, on the discovery that the expression levels of RITs (e.g., those listed in Table 2, Table 7, and/or Table 11) can be used to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected at a time point prior to the emergence of any visually-observable, histological sign of tissue rejection (e.g., tubulitis for kidney rejection). In some embodiments, expression levels of GRITs or GRIT-like transcripts, including, for example, those listed in Tables 4, 5, and 9 can be assessed to determine whether or not transplanted tissue is being rejected or to distinguish transplanted tissue that is being rejected from transplanted tissue that is not being rejected.
In one aspect, this document features a method for detecting tissue rejection. The method can include determining whether or not tissue transplanted into a mammal contains cells that express at least two of the nucleic acids listed in Table 2 or Table 11 at elevated levels, wherein the presence of the cells indicates that the tissue is being rejected. The mammal can be a human. The tissue can be kidney tissue or a kidney. The method can include determining whether or not the tissue contains cells that express at least five of the nucleic acids, at least ten of the nucleic acids, or at least twenty of the nucleic acids. The determining step can include measuring the level of mRNA expressed from the at least two nucleic acids or measuring the level of polypeptide expressed from the at least two nucleic acids. The method can include determining whether or not the tissue contains cells that express at least two of the nucleic acids at a level greater than the average level of expression exhibited in cells from control tissue that has not been transplanted.
In another aspect, this document features a method for detecting tissue rejection. The method can include determining whether or not a sample contains cells that express at least two of the nucleic acids listed in Table 2 or Table 11 at elevated levels, wherein the sample contains cells, was obtained from tissue that was transplanted into a mammal, and was obtained from the tissue within fifteen days of the tissue being transplanted into the mammal, and wherein the presence of the cells indicates that the tissue is being rejected. The mammal can be a human. The tissue can be kidney tissue or a kidney. The method can include determining whether or not the sample contains cells that express at least five of the nucleic acids, at least ten of the nucleic acids, or at least twenty of the nucleic acids. The determining step can include measuring the level of mRNA expressed from the at least two nucleic acids or measuring the level of polypeptide expressed from the at least two nucleic acids. The sample can be obtained from the tissue within ten days of the tissue being transplanted into the mammal or within five days of the tissue being transplanted into the mammal. The method can include determining whether or not the sample contains cells that express at least two of the nucleic acids at a level greater than the average level of expression exhibited in cells from control tissue that has not been transplanted.
In another aspect, this document features a nucleic acid array containing at least 20 nucleic acid molecules, wherein each of the at least 20 nucleic acid molecules has a different nucleic acid sequence, and wherein at least 50 percent of the nucleic acid molecules of the array contain a sequence from nucleic acid selected from the group consisting of the nucleic acids listed in Table 2 and Table 11. The array can contain at least 50 nucleic acid molecules, wherein each of the at least 50 nucleic acid molecules has a different nucleic acid sequence. The array can contain at least 100 nucleic acid molecules, wherein each of the at least 100 nucleic acid molecules has a different nucleic acid sequence. Each of the nucleic acid molecules that contain a sequence from a nucleic acid selected from the group can contain no more than three mismatches. At least 75 percent of the nucleic acid molecules of the array can contain a sequence from nucleic acid selected from the group. At least 95 percent of the nucleic acid molecules of the array can contain a sequence from nucleic acid selected from the group. The array can include glass. The at least 20 nucleic acid molecules can contain a sequence present in a human.
In another aspect, this document features a computer-readable storage medium having instructions stored thereon for causing a programmable processor to determine whether one or more nucleic acids listed in Table 2 or Table 11 are detected in a sample, wherein the sample is from a transplanted tissue. The computer-readable storage medium can further have instructions stored thereon for causing a programmable processor to determine whether one or more of the nucleic acids listed in Table 2 or Table 11 is expressed at a greater level in the sample than in a control sample of non-transplanted tissue.
This document also features an apparatus for determining whether a transplanted tissue is being rejected. The apparatus can include one or more collectors for obtaining signals representative of the presence of one or more nucleic acids listed in Table 2 or Table 11 in a sample from the transplanted tissue, and a processor for analyzing the signals and determining whether the tissue is being rejected. The one or more collectors can be configured to obtain further signals representative of the presence of the one or more nucleic acids in a control sample from non-transplanted tissue.
Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, suitable methods and materials are described below. All publications, patent applications, patents, and other references mentioned herein are incorporated by reference in their entirety. In case of conflict, the present specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and not intended to be limiting.
The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.
DESCRIPTION OF DRAWINGS FIG. 1 is a depiction of selection criteria used for identification of GRITs and GRIT-like transcripts. WT D5—wild type allografts, GKO D5—IFN-γ-deficient allografts.
FIG. 2A is a depiction of an unsupervised hierarchical clustering of GRITs. FIG. 2B is a graph showing an expression time course of GRITs in injury and rejection. FIG. 2C is a graph showing the signal strength of IFN-γ over the time course of in injury and rejection. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.
FIG. 3A is a depiction of an unsupervised hierarchical clustering of GRIT-like transcripts. FIG. 3B is a graph showing an expression time course of GRIT-like transcripts in injury and rejection. Normalized values are shown. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.
FIGS. 4A, 4B, and 4C are graphs showing expression profiles of IFN-γ, GRITs, and GRIT-like transcripts, respectively, early after transplantation. ISO—isografts, WT—allografts, GKO D5—IFN-γ deficient grafts, NCBA—control kidneys.
FIG. 5A is a depiction of an unsupervised hierarchical clustering of injury-induced RIT. FIG. 5B is a graph showing an expression time course of RIT in injury and rejection. Normalized values are shown. Clustering was based on distance as the similarity measure. ISO—isografts, WT—allografts, NCBA—control kidneys.
FIG. 6A is a graph showing expression profiles of acute phase markers in isografts and allografts. FIG. 6B is a graph showing the expression profiles of Tgfbi and the average expression profile of injury-induced RIT in isografts and allografts. Normalized values are shown in both graphs. ISO—isografts, WT—allografts, NCBA—control kidneys.
FIG. 7A is a graph showing an expression profile of Tgfbi superimposed on that for injury-induced RIT. FIG. 7B is a graph showing an expression profile of STAT-1 superimposed on that for injury-induced RIT.
FIG. 8A is a diagram of an algorithm for identifying GRITs. FIG. 8B is a diagram of an algorithm for identifying RITs. FIG. 8C is a diagram of an algorithm for identifying tGRITs and oGRITs.
FIG. 9 is a diagram of an algorithm for identifying IRITs.
DETAILED DESCRIPTION This description provides methods and materials involved in detecting tissue rejection (e.g., organ rejection). For example, this description provides methods and materials that can be used to diagnose a mammal (e.g., a human) as having transplanted tissue that is being rejected. A mammal can be diagnosed as having transplanted tissue that is being rejected if it is determined that the tissue contains cells that express elevated levels of one or more RITs or that express elevated levels one or more of the nucleic acids listed in Table 2, Table 7, or Table 11. In some embodiments, a mammal can be diagnosed as having transplanted tissue that is being rejected if it is determined that the tissue contains cells that express elevated levels of one or more GRITs, GRIT-like, true GRIT, or occult GRIT transcripts including, without limitation, those listed in Tables 4, 5, 9, or 10, respectively.
The methods and materials provided herein can be used to detect tissue rejection in any mammal such as a human, monkey, horse, dog, cat, cow, pig, mouse, or rat. In addition, the methods and materials provided herein can be used to detect rejection of any type of transplanted tissue including, without limitation, kidney, heart, liver, pancreas, and lung tissue. For example, the methods and materials provided herein can be used to determine whether or not a human who received a kidney transplant is rejecting that transplanted kidney.
Any type of sample containing cells can be used to determine whether or not transplanted tissue contains cells that express one or more RITs or that express one or more of the nucleic acids listed in Table 2, Table 7, or Table 11 at elevated levels. Similarly, any type of sample containing cells can be used to determine whether or not transplanted tissue contains cells that express one or more GRITs, GRIT-like, true GRIT, or occult GRIT transcripts, or that express one or more of the nucleic acids listed in Table 4, Table 5, Table 9, or Table 10 at elevated levels. For example, biopsy (e.g., punch biopsy, aspiration biopsy, excision biopsy, needle biopsy, or shave biopsy), tissue section, lymph fluid, blood, and synovial fluid samples can be used. In some embodiments, a tissue biopsy sample can be obtained directly from the transplanted tissue. In some embodiments, a lymph fluid sample can be obtained from one or more lymph vessels that drain from the transplanted tissue. A sample can contain any type of cell including, without limitation, cytotoxic T lymphocytes, CD4+ T cells, B cells, peripheral blood mononuclear cells, macrophages, kidney cells, lymph node cells, or endothelial cells.
As explained herein, a RIT refers to a transcript that is elevated at least 2-fold in WT kidney allografts at day 5 post transplant in WT hosts vs. normal kidneys. Examples of RITs include, without limitation, those listed in Tables 2, 7, and 11. A GRIT refers to an IFN-γ and rejection induced transcript that is (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) expressed at levels at least 2-fold lower in kidney tissue from IFN-γ-deficient (GKO) D5 allografts as compared to WT D5 allografts. Examples of GRITs include, without limitation, the nucleic acids listed in Table 4. A GRIT-like transcript refers to a transcript that is (a) expressed at a level at least 2-fold greater in kidney tissue of mammals treated with IFN-γ than in kidney tissue of untreated mammals, (b) elevated at least 2-fold in tissue from WT kidney allografts at day 5 post transplant in WT hosts as compared to normal kidney tissue, and (c) not lower or even increased when IFN-γ is absent in GKO D5 allografts compared to WT D5 allografts. Examples of GRIT-like transcripts include, without limitation, those listed in Table 5. Additional examples of RITs, GRITs, and GRIT-like transcripts can be identified using the procedures described herein. For example, the procedures described in Example 1 can be used to identify RITs, GRITs, and GRIT-like transcripts other than those listed in Tables 2, 4, 5, and 7.
A tGRIT refers to a unique transcript that is rejection-induced and IFN-γ-dependent in rejection, and also is increased at least two-fold by rIFN-γ. Examples of tGRITs include, without limitation, those listed in Table 9. An oGRIT refers to a GRIT that is a unique transcript, but that is not induced at least 2-fold by rIFN-γ in normal kidneys. Examples of oGRITs include, without limitation, those listed in Table 10. An IRIT refers to a transcript that is increased at least two-fold in isografts at least once between day 1 and day 21, as compared to normal kidney, and also increased at least two-fold in CBA allografts at day 5 as compared to normal kidneys. Examples of IRITs include, without limitation, those listed in Table 11. The procedures described in Example 2 can be used to identify RITs, IRITs, GRITs, true GRITs, and occult GRITs other than those listed in Tables 9, 10, and 11.
The expression of any number of RITs, IRITs, GRITs, GRIT-like transcripts, tGRITs, oGRITs, or nucleic acids listed in Tables 2, 4, 5, 7, 9, 10, and/or 11 can be evaluated to determine whether or not transplanted tissue will be rejected. For example, the expression of one or more than one (e.g., two, three, four, five, six, seven, eight, nine, ten, 15, 20, 25, 30, 40, 50, 75, 100, or more than 100) of the nucleic acids listed in Table 2 can be used. In some embodiments, determining that a nucleic acid listed in Table 2 is expressed in a sample at a detectable level can indicate that the transplanted tissue will be rejected. In some embodiments, transplanted tissue can be evaluated by determining whether or not the tissue contains cells that express a nucleic acid listed in Table 2 at an elevated level, i.e., a level that is greater than the average expression level observed in control cells obtained from tissue that has not been transplanted. Typically, a nucleic acid can be classified as being expressed at a level that is greater than the average level observed in control cells if the expression levels differ by at least 1-fold (e.g., 1.5-fold, 2-fold, 3-fold, or more than 3-fold). Control cells typically are the same type of cells as those being evaluated. In some cases, the control cells can be isolated from kidney tissue that has not been transplanted into a mammal. Any number of tissues can be used to obtain control cells. For example, control cells can be obtained from one or more tissue samples (e.g., at least 5, 6, 7, 8, 9, 10, or more tissue samples) obtained from one or more healthy mammals (e.g., at least 5, 6, 7, 8, 9, 10, or more healthy mammals).
Any suitable method can be used to determine whether or not a particular nucleic acid is expressed at a detectable level or at a level that is greater than the average level of expression observed in control cells. For example, expression of a particular nucleic acid can be measured by assessing mRNA expression. mRNA expression can be evaluated using, for example, northern blotting, slot blotting, quantitative reverse transcriptase polymerase chain reaction (RT-PCR), real-time RT-PCR, or chip hybridization techniques. Methods for chip hybridization assays include, without limitation, those described herein. Such methods can be used to determine simultaneously the relative expression levels of multiple mRNAs. Alternatively, expression of a particular nucleic acid can be measured by assessing polypeptide levels. For example, polypeptide levels can be measured using any method such as immuno-based assays (e.g., ELISA), western blotting, or silver staining.
The methods and materials provided herein can be used at any time following a tissue transplantation to determine whether or not the transplanted tissue will be rejected. For example, a sample obtained from transplanted tissue at any time following the tissue transplantation can be assessed for the presence of cells expressing elevated levels of a nucleic acid listed in Table 2. In some cases, a sample can be obtained from transplanted tissue 1, 2, 3, 4, 5, 6, 7, 8, or more hours after the transplanted tissue was transplanted. In some cases, a sample can be obtained from transplanted tissue one or more days (e.g., 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 40, or more days) after the transplanted tissue was transplanted. Typically, a sample can be obtained from transplanted tissue 2 to 7 days (e.g., 5 to 7 days) after transplantation and assessed for the presence of cells expressing elevated levels of one or more RITs or expressing elevated levels of one or more nucleic acids listed in Table 2.
This description also provides nucleic acid arrays. The arrays provided herein can be two-dimensional arrays, and can contain at least 10 different nucleic acid molecules (e.g., at least 20, at least 30, at least 50, at least 100, or at least 200 different nucleic acid molecules). Each nucleic acid molecule can have any length. For example, each nucleic acid molecule can be between 10 and 250 nucleotides (e.g., between 12 and 200, 14 and 175, 15 and 150, 16 and 125, 18 and 100, 20 and 75, or 25 and 50 nucleotides) in length. In addition, each nucleic acid molecule can have any sequence. For example, the nucleic acid molecules of the arrays provided herein can contain sequences that are present within the nucleic acids listed in Table 2, Table 4, Table 5, Table 7, Table 9, Table 10, and/or Table 11. For the purpose of this document, a sequence is considered present within a nucleic acid listed in, for example, Table 2 when the sequence is present within either the coding or non-coding strand. For example, both sense and anti-sense oligonucleotides designed to human Abp1 nucleic acid are considered present within Abp1 nucleic acid.
Typically, at least 25% (e.g., at least 30%, at least 40%, at least 50%, at least 60%, at least 75%, at least 80%, at least 90%, at least 95%, or 100%) of the nucleic acid molecules of an array provided herein contain a sequence that is (1) at least 10 nucleotides (e.g., at least 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, or more nucleotides) in length and (2) at least about 95 percent (e.g., at least about 96, 97, 98, 99, or 100) percent identical, over that length, to a sequence present within a nucleic acid listed in Table 2, Table 4, Table 5, Table 7, Table 9, Table 10, or Table 11. For example, an array can contain 100 nucleic acid molecules located in known positions, where each of the 100 nucleic acid molecules is 100 nucleotides in length while containing a sequence that is (1) 30 nucleotides in length, and (2) 100 percent identical, over that 30 nucleotide length, to a sequence of one of the nucleic acids listed in Table 2. A nucleic acid molecule of an array provided herein can contain a sequence present within a nucleic acid listed in Table 2, where that sequence contains one or more (e.g., one, two, three, four, or more) mismatches.
The nucleic acid arrays provided herein can contain nucleic acid molecules attached to any suitable surface (e.g., plastic or glass). In addition, any method can be use to make a nucleic acid array. For example, spotting techniques and in situ synthesis techniques can be used to make nucleic acid arrays. Further, the methods disclosed in U.S. Pat. Nos. 5,744,305 and 5,143,854 can be used to make nucleic acid arrays.
Computer-Readable Medium and an Apparatus for Predicting Rejection This disclosure further provides a computer-readable storage medium configured with instructions for causing a programmable processor to determine whether a transplanted tissue is being or is likely to be rejected. The determination of whether a transplanted tissue is being or will be rejected can be carried out as described herein; that is, by determining whether one or more of the nucleic acids listed in Table 2 or Table 11 is detected in a sample (e.g., a sample of the tissue), or is expressed at a level that is greater than the level of expression in a corresponding tissue that is not transplanted. The processor also can be designed to perform functions such as removing baseline noise from detection signals.
Instructions carried on a computer-readable storage medium (e.g., for detecting signals) can be implemented in a high level procedural or object oriented programming language to communicate with a computer system. Alternatively, such instructions can be implemented in assembly or machine language. The language further can be compiled or interpreted language.
The nucleic acid detection signals can be obtained using an apparatus (e.g., a chip reader) and a determination of tissue rejection can be generated using a separate processor (e.g., a computer). Alternatively, a single apparatus having a programmable processor can both obtain the detection signals and process the signals to generate a determination of whether rejection is occurring or is likely to occur. In addition, the processing step can be performed simultaneously with the step of collecting the detection signals (e.g., “real-time”).
Any suitable process can be used to determine whether a transplanted tissue is being or is likely to be rejected. In some embodiments, for example, a process can include determining whether a pre-determined number (e.g., one, two, three, four, five, six, seven, eight, nine, ten, 15, 20, 25, 30, 40, 50, 75, 100, or more than 100) of the nucleic acids listed in Table 2 or Table 11 is expressed in a sample (e.g., a sample of transplanted tissue) at a detectable level. If the number of nucleic acids that are expressed in the sample is equal to or exceeds the pre-determined number, the transplanted tissue can be predicted to be rejected. If the number of nucleic acids that are expressed in the sample is less than the pre-determined number, the transplanted tissue can be predicted to not be rejected. The steps of this process (e.g., the detection, or non-detection, of each of the nucleic acids listed in Table 2 or Table 11) can be carried out in any suitable order. In some embodiments, a process can include determining whether a pre-determined number of the nucleic acids listed in Table 2 or Table 11 is expressed in a sample at a level that is greater than the average level observed in control cells (e.g., cells obtained from tissue that has not been transplanted. If the number of nucleic acids having increased levels of expression in the sample is equal to or exceeds the pre-determined number, the transplanted tissue can be predicted to be rejected. If the number of nucleic acids having increased expression levels in the sample is less than the pre-determined number, the transplanted tissue can be predicted to not be rejected. Again, the steps of this process can be carried out in any suitable order.
Also provided herein, therefore, is an apparatus for determining whether a transplanted tissue is being or is likely to be rejected. An apparatus for determining whether tissue rejection will occur can include one or more collectors for obtaining signals from a sample (e.g., a sample of nucleic acids hybridized to nucleic acid probes on a substrate such as a chip) and a processor for analyzing the signals and determining whether rejection will occur. By way of example, the collectors can include collection optics for collecting signals (e.g., fluorescence) emitted from the surface of the substrate, separation optics for separating the signal from background focusing the signal, and a recorder responsive to the signal, for recording the amount of signal. The collector can obtain signals representative of the presence of one or more nucleic acids listed in Table 2 or Table 11 (e.g., in samples from transplanted and/or non-transplanted tissue). The apparatus further can generate a visual or graphical display of the signals, such as a digitized representation. The apparatus further can include a display. In some embodiments, the apparatus can be portable.
The invention will be further described in the following examples, which do not limit the scope of the invention described in the claims.
EXAMPLES Example 1 Interactions Between IFN-γ-Induced Transcripts and Injury Effects The roles of IFN-γ were investigated in a mouse kidney allograft model that develops the pathologic lesions that are diagnostic in human graft rejection. Basically, a comparison of mouse kidney pathology to the mouse transcriptome was used to guide understanding of the relationship of lesions to transcriptome changes in human rejection. Recombinant IFN-γ (rIFN-γ) was administered to WT mice to identify the GITs in the kidney and examined how the GITs changed during graft rejection, comparing WT to IFN-γ deficient grafts. These experiments have provided insight into some of the complex relationships between IFN-γ inducibility during rejection and in tissue injury and regulation of GITs by non IFN-γ dependent factors during kidney transplantation.
Materials and Methods
Mice: Male CBA/J (CBA) and C57Bl/6 (B6) mice were obtained from the Jackson Laboratory (Bar Harbor, Me.). IFN-γ deficient mice (BALB/c.GKO) and (B6.129S7-IFNgtm1Ts; B6.GKO) were bred in the Health Sciences Laboratory Animal Services at the University of Alberta. Mice maintenance and experiments were in conformity with approved animal care protocols. CBA (H-2K, I-Ak) into C57Bl/6 (B6; H-2KbDb, I-Ab) mice strain combinations, BALB/c.GKO into B6.GKO were studied across full MHC and non-MHC disparities.
Renal transplantation: Renal transplantation was performed as a non life-supporting transplant model. Recovered mice were killed at day 5, 7, 14, 21 or 42 post-transplant. Kidneys were removed, snap frozen in liquid nitrogen and stored at −70° C. No mice received immunosuppressive therapy. Kidneys with technical complications or infection at the time of harvesting were removed from the study.
Treatment with recombinant IFN-γ. CBA mice were injected i.p with 300,000 I.U. of recombinant INF-γ at 0 and 24 hours. rIFN-γ was a generous gift from Dr. T. Stewart at Genentech (South San Francisco, Calif.). Mice were sacrificed after 48 hours.
Microarrays: High-density oligonucleotide Genechip 430A and 430 2.0 arrays, GeneChip T7-Oligo(dT) Promotor Primer Kit, Enzo BioArray HighYield RNA Transcript Labeling Kit, IVT Labeling KIT, GeneChip Sample Cleanup Module, IVT cRNA Cleanup Kit were purchased from Affymetrix (Santa Clara, Calif.). RNeasy Mini Kit was from Qiagen (Ont, Canada), Superscript II, E. coli DNA ligase, E. coli DNA polymerase I, E. coli Rnase H, T4 DNA polymerase, 5× second strand buffer, and dNTPs were from Invitrogen Life Technologies.
RNA preparation and hybridization: Total RNA was extracted from individual kidneys using the guanidinium-cesium chloride method and purified RNA using the RNeasy Mini Kit (Quiagen, Ont. Canada). RNA yields were measured by UV absorbance. The quality was assessed by calculating the absorbance ratio at 260 nm and 280 nm, as well as by using an Agilent BioAnalyzer to evaluate 185 and 28S RNA integrity.
For each array, RNA from 3 mice was pooled. RNA processing, labeling and hybridization to MOE430A or MOE430 2.0 arrays was carried out according to the protocols included in the Affymetrix GeneChip Expression Analysis Technical Manual (available on the World Wide Web at affymetrix.com). cRNA used for Moe 430 2.0 arrays was labeled and fragmented using an IVT Labeling Kit and IVT cRNA Cleanup Kit.
Sample designation: Normal control kidneys were obtained from CBA mice and designated as NCBA. Allografts rejecting in wild type hosts (B6) at day 5 through day 42 post transplant were designated as WT D5, D7, D14, D21 and D42, respectively. Corresponding isografts were designated Iso D5, D7 and D21. Kidneys from mice treated with recombinant IFN-γ and harvested after 48 h were designated rIFN-γ. BALB/c-GKO kidneys (deficient in IFN-γ) rejecting in IFN-γ-deficient B6 hosts at day 5 were designated as GKO D5 and corresponding isografts were designated ISO.GKO D5. The following samples (each consisting of RNA pooled from 3 mice) were analyzed by the Moe 430A arrays: two biological replicates of Iso D7, WT (D7, D14, D21 and D42); three replicates for NCBA and WT D5, single samples for Iso D5 and D21. Samples analyzed by the Moe 430 2.0 were NCBA (three replicates), WT D5, GKO D5, ISO.GKO D5 and rIFN-γ (two replicates each).
Sample analysis: Microarray Suite Expression Analysis 5.0 software was used for analysis of Moe 430A arrays (MAS 5.0, Affymetrix), and Gene Chip Operating software (GCOS 2.0, Affymetrix) was used for analysis of Moe 430 2.0 arrays to calculate absolute signal strength and transcripts flagging. Normalization per chip and per gene (GeneSpring™ 7.2, Agilent, Palo Alto Calif.) and to the control samples (NCBA) were described previously. The mean normalized value for further analysis of replicate samples.
Transcripts of interest were selected based on 2-fold differences and significance by Welch's t-test (Anova parametric test, variances not assumed equal). Groups of selected transcripts were then compared for individual time points using the univariate analysis of variance (Unianova with Bonferroni post hoc tests, for log transformed normalized data, SSPS 11.0 statistical package).
Hierarchical cluster analysis was performed using GeneSpring 7.2. Data were log transformed and similarity of transcript expression between experimental groups and between individual transcripts was visualized by a condition and gene tree diagram. Similarity measurements were based on distance. Trajectory clustering (expression pattern comparison, 0.95 correlation coefficient) was performed using the “find similar gene” feature in GeneSpring package.
Results
Terminology: rIFN-γ induced transcripts (GITs) were identified as those increased 48 hours after two injections of rIFN-γ, spaced 24 hours apart. Rejection induced transcripts (RITs) were identified as those increased in allografts at day 5. Injury-induced transcripts were identified as those induced in isografts at days 5 and/or 7. The rejection induced transcripts thus include effects of transplant-related stress as well as alloimmune related changes.
Identification of transcripts induced by IFN-γ in vivo in rejecting kidney allografts: Identification of IFN-γ induced transcripts in kidney allografts was based on data obtained from the Moe 430 2.0 arrays, with cytotoxic T lymphocyte associated transcripts (CATs) deleted from all lists to avoid overlap. First, the rIFN-γ-induced transcripts were identified: 342 transcripts flagged present and increased 2-fold in normal kidneys from mice treated with rIFN-γ (significant by ANOVA) (Table 1). RITs were then selected, defined as transcripts that were elevated 2-fold in WT allografts at day 5 post transplant in WT hosts vs. normal kidneys (significant by Anova). 2040 transcripts, flagged present in the allografts, fulfilled these criteria (Table 2). To determine how many of these transcripts were IFN-γ inducible, they were compared to the GITs. This comparison yielded 163 common transcripts that were induced by rIFN-γ treatment and increased in rejecting kidneys at day 5. Thus, 179 GITs were not significantly induced in rejecting kidneys by these criteria, in spite of the strong IFN-γ response in the allograft.
Validation of IFN-γ induced transcripts in mouse kidney allografts: To verify that the increased expression of 163 transcripts in day 5 allografts was at least partially dependent on IFN-γ, IFN-γ-deficient kidney allografts grafted into IFN-γ-deficient hosts were studied. In these grafts, neither the donor nor the host cells can make IFN-γ. After removing CATs, 570 transcripts were expressed at least 2-fold lower in GKO D5 compared to WT D5 (significant by ANOVA), indicating that the expression of these transcripts was affected by the presence or absence of IFN-γ in allografts (Table 3). Of the 163 previously defined rIFN-γ- and rejection-induced transcripts, 74 were decreased in GKO D5, indicating that they were at least partially dependent on IFN-γ in WT D5 allografts. These were termed IFN-γ and rejection-inducible transcripts (GRITs). On the other hand, 89 transcripts, despite being rIFN-γ-inducible, were not lower or were even increased when IFN-γ was absent in GKO D5 allografts compared to WT D5 allografts. These were termed GRIT-like transcripts. Thus, the GRIT-like transcripts, despite being inducible by rIFN-γ, were increased in allografts by mechanisms largely independent of IFN-γ. The algorithm used for transcript selection is shown in FIG. 1.
Functional classification of GRIT and GRIT-like: The list of GRITs (Table 4) summarizes local effects of IFN-γ on transcription in the isografts and the allografts, as well as systemic effects on the normal rejecting kidney. The transcripts represent genes for several major classes of proteins: (a) MHCs and their related factors (B2m Psmb8-9, Tapbp) and other ubiquitination/proteolysis-related factors (Parp14, Psmb10, Ubd, Ubl1); (b) guanylate binding proteins (Gbp2), interferon-induced GTPases (Igtp, Iigp1, Tgtp) and other so called IFN-γ-induced proteins (Ifi1 and Ifi47); (c) cytokines and chemokines: Ccl5, Ccl8, Cxcl 9, Cxcl10, interleukin-18 binding protein (Il18 bp), Arts1; (d) other immune functions: complement components (C1r, C1s, C2); and (e) transcription factors and activators: Irf7 (ISRE sites), Stat1 (GAS sites), class II transactivator C2ta.
The list of GRIT-like transcripts (Table 5) includes complement components (C1qb, C1qg, Serping1); cytokine, chemokine and receptor related transcripts (Tnfsf13b, Ccr5, Cxcl14, Socs2); some interferon-induced transcripts (Ifi27, Ifitm1, Ifitm6); and Tgfbi, a transcript whose expression is regulated by Tgfb1.
Expression profiles of GRIT and GRIT-like in the isografts and the allografts: The time course of changes in these transcripts post transplant was studied by querying a previously established database from MOE 430A arrays containing the expression values of all transcripts in isografts and allografts, at different times post transplant. Previously identified GRITs were “translated” (using the GeneSpring translation feature) to Moe 430A arrays, and these increased at least 2 fold (significant by Anova) in WT D5 allografts vs NCBA were selected. This permitted creation of a final list of 59 GRITs (Table 4) and 42 GRIT-like transcripts (Table 5). The lower number of transcripts was due to a lack of certain probe sets interrogating Riken sequences in Moe 430A arrays, and perhaps also to the lower sensitivity of the M430A arrays.
Analysis of the expression time course of GRITs and GRIT-like transcripts in isografts and allografts permitted comparison of the impact of transplant-related stress and/or injury on rejection. First, unsupervised clustering of all isografts and allografts was performed based on GRITs and GRIT-like lists (FIG. 2 and FIG. 3). Kidney samples were grouped into two clusters. One powerful cluster included all of the allografts, indicating strong and consistent expression of the GRITs and GRIT-like transcripts in all allografts at all times tested. Surprisingly, ISO D5 clustered with all allografts for the GRITs (FIG. 2). ISO D21 co-clustered with NCBA, indicating recovery of kidneys from injury. ISO D7 was more similar to this group. On the other hand, GRIT-like list yielded good separation of the all isografts from the allografts, clustering ISO D5 and ISO D7 in one subgroup (FIG. 3). This indicated a stronger relation of GRIT expression in ISO D5 to rejecting allografts, compared to GRIT-like expression.
Time course of GRIT expression parallels IFN-γ expression: The time course of GRIT expression supported the cluster organization and the conclusion that there were differences in regulation of GRITs (FIG. 2) versus GRIT-like transcripts (FIG. 3). In the isografts, expression of many GRITs peaked at D5 post transplant and sharply declined at D7 and D21. Thirty-nine and 11 GRITs were increased at least 2-fold at ISO D5 and ISO D7, respectively. Mean expression of GRITs in ISO D5 samples was higher than in ISO D7 and D21 (p<0.01). GRIT expression in the allografts, however, was sustained throughout the observation period, with no significant differences among the samples except for a small peak at D14 (p<0.05). In addition, GRIT expression in the allografts showed 4-fold higher mean expression compared to ISO D5 (p<0.02, corrected for multiple comparisons).
For the comparison, FIG. 2A demonstrates the time course of IFN-γ expression in the isografts D5 throughout D21 and the allografts day 5 throughout day 42. Isograft IFN-γ transcript levels peaked at D5 and declined from D7 on (FIGS. 2B and 2C). However, IFN-γ transcript levels were 5-fold higher in WT D5 allografts compared to ISO D5, and remained high at all allograft time points, with some increase at day 14. Thus GRIT expression parallels that of IFN-γ.
IFN-γ expression also was assessed in WT allografts at early times post transplant. IFN-γ signal strength increased about 8 fold in D5 compared to D3 allografts (FIG. 4A), indicating that the IFN-γ expression was established at D5 post transplant.
Time course of GRIT-like transcripts parallels TGF-β1 expression: GRIT-like transcripts were analyzed over the time course shown in FIG. 3A, and showed consistent expression in all allografts. However, they differed in isografts: there was no statistically significant difference between their mean expression at ISO D5 and ISO D7 (FIG. 3B). 17 GRIT-like allografts were increased at least 2-fold either in ISO D5 or ISO D7 samples. Mean GRIT-like expression was 2 fold higher compared to ISO D5 or ISO D7 (p<0.02, corrected for multiple comparisons). However, GRIT-like mean expression in the isografts and the allografts was lower by 2-fold compared to GRITs.
The appearance of Tgfbi in the GRIT-like list suggests that Tgfb1 may be playing a role in the regulation of some of these transcripts. Moreover, the GRIT-like transcripts, by definition, are not significantly reduced in the absence of IFN-γ, indicating that they are induced by other factors, one candidate being Tgf-β1. The expression profile of Tgfbi was reminiscent of Tgfb1, i.e., it demonstrated a similar peak in ISO D7 and strong increase in the allografts, like many of the GRIT-like transcripts.
The expression time course of GRIT/GRIT-like in WT allografts at early times post transplant demonstrated a step-wise increase from day 3 to day 4 to day 5 post transplant (FIGS. 4B and 4C).
Expression of GRITs and GRIT-like in the isografts differ in response to IFN-γ. To confirm that the elevated expression of GRIT in wild type isografts is dependent on IFN-γ, the expression of GRITs was assessed in the IFN-γ-deficient D5 isografts (ISO.GKO D5) by Moe 430 2.0 arrays and compared to GRIT expression in wild type isografts D5. Transcripts that were increased at least 2-fold in WT D5 vs to ISO.GKO D5 were translated to Moe 430A arrays. It was observed that 36 out of 59 GRITs (Table 4) were expressed at least 2-fold higher in WT D5 isografts compared to ISO.GKO D5. Notably, only 10 GRIT-like transcripts fulfilled these criteria (Table 5). Thus, the majority (66%) of GRITs and only a fraction (25%) of GRIT-like transcripts seemed to be dependent on IFN-γ produced in the isografts.
Regulation of the expression of injury and rejection induced transcripts that are not IFN-γ regulated by these criteria: Due to the uniformity with which the GRITs and GRIT-like transcripts were increased in the isografts (albeit to a varying degree in ISO D5 and ISO D7 samples), the analysis of transplant stress/injury to rejection was extended by analyzing all transcripts flagged present and elevated 2-fold either in isografts at days 5 or 7 and increased 2-fold in WT D5 (significant by Anova). GRITs, GRIT-like and CATs were eliminated from this list. Moreover, transcripts were detected that were decreased 2-fold or more in GKO D5 compared to WT D5, but were not affected by rIFNγ administration. One hundred ten of these transcripts translated to Moe 430A arrays (Table 6) and were eliminated from the RIT list.
The analysis yielded many transcripts that behaved like the GRIT-like transcripts, with a peak at day 7 and consistent high expression in all allografts. As listed in Table 7, 147 injury-induced RITs met these conditions in Moe 430A database. Unsupervised clustering based on this list grouped ISO D7 samples with the allografts (FIG. 5A). Expression pattern of these transcripts confirmed the clustering result. Injury-induced RITs peaked in ISO D7 isografts rather than ISO D5 (FIG. 5B; significant by Anova). One hundred forty RITs were increased 2-fold or more at ISO D7, including the acute-phase response markers: serum amyloids 1-3 and ceruloplasmin, while 54 were increased at ISO D5. The mean expression of RITs was more elevated and sustained in the allografts compared to ISO D7 and ISO D5, with a peak in WT D14 allografts (FIG. 5B, significant by Anova). A Medline-assisted literature search revealed that expression of the injury-induced RITs transcripts could be dependent on either IFN-γ or Tgfb1, or both. IFN-γ control was reported for Vim, Ccl2, Arrb2 (also reported as a possible marker of human heart rejection), ceruloplasmin, Fn1, Fos, Socs3, Timp1, Ncf2, Fcgr3, Plek, and Casp12. Tgfb1 control was reported for transcripts Tgfbi, collagen type 1a2 and 3a1, Socs3, Lox, Cspg2, Fn1, Postn (periostin, homologous to Tgfbi) (Table 8).
The expression profiles of these transcripts were then analyzed, and it was observed that the average expression pattern of injury-induced RITs was significantly similar to the Tgfbi expression profile, as assessed by the trajectory profiling i.e. “find similar gene(s)” feature of GeneSpring (FIGS. 6A and 6B). Next, the expression profiles of a selected prototypic GRIT (Stat1, which was elevated in isografts) and a prototypic GRIT-like transcript (Tgfbi) were compared to the expression profiles of injury-induced RITs. Using the trajectory clustering, 50 transcripts were found with patterns similar to that of Tgfbi (FIG. 7A), and 43 transcripts were found with patterns similar to that of STAT-1 (FIG. 7B). RITs showing Stat-1-like profiles had substantial overlap (39 transcripts) with Tgfbi-like profiles.
TABLE 1
rIFN-γ-induced transcripts (GITs)
rIFNg
Gene Symbol NCBA vs
Affymetrix Gene Title Affymetrix Raw NCBA Genbank
— — 1241 3.2 AV290571
— — 855 3.0 AV227574
— — 12 2.2 BB416480
— — 127 2.0 BB291656
— — 219 3.0 BB533460
— — 25 2.8 AW554440
— — 83 2.3 BB308208
Oasl2 2′-5′ oligoadenylate synthetase-like 2 209 2.2 BQ033138
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A 291 2.8 BB123978
reductase
Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A 83 5.8 BC014714
synthase 2
Arf3 ADP-ribosylation factor 3 107 2.6 BQ175059
Akr1c18 aldo-keto reductase family 1, member C18 314 7.9 NM_134066
Akr1c20 aldo-keto reductase family 1, member C20 28 15.8 BC021607
Angptl3 angiopoietin-like 3 253 3.7 BC019491
Arg2 arginase type II 85 9.3 AV002218
Arvcf armadillo repeat gene deleted in velo- 153 2.0 BE947943
cardio-facial syndrome
Astn1 astrotactin 1 21 2.7 NM_007495
Atp8a1 ATPase, aminophospholipid transporter 150 2.1 BQ176779
(APLT), class I, type 8A, member 1
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 33 3.3 AV325919
polypeptide
Abcb1a ATP-binding cassette, sub-family B 40 3.9 M30697
(MDR/TAP), member 1A
Abcb1a ATP-binding cassette, sub-family B 142 3.8 M30697
(MDR/TAP), member 1A
Abcc3 ATP-binding cassette, sub-family C 130 17.7 AK006128
(CFTR/MRP), member 3
Bhlhb5 basic helix-loop-helix domain containing, 113 2.0 NM_021560
class B5
B2m beta-2 microglobulin 9650 2.6 AI099111
B2m beta-2 microglobulin 71 3.5 AA170322
B2m beta-2 microglobulin 13469 2.0 BF715219
Bhmt betaine-homocysteine methyltransferase 331 9.6 NM_016668
Bace beta-site APP cleaving enzyme 152 4.1 BB114336
Baat bile acid-Coenzyme A: amino acid N- 17 11.2 NM_007519
acyltransferase
Cdh11 cadherin 11 381 2.0 NM_009866
Car5a carbonic anhydrase 5a, mitochondrial 98 2.2 NM_007608
Cart1 cartilage homeo protein 1 57 2.4 BB366930
Ctss cathepsin S 838 2.6 NM_021281
BC011209 cDNA sequence BC011209 437 2.0 BC011209
BC021340 cDNA sequence BC021340 256 2.2 BC021340
BC060267 cDNA sequence BC060267 59 2.2 BB124106
Ceacam1 CEA-related cell adhesion molecule 1 296 3.0 M77196
Ceacam1 CEA-related cell adhesion molecule 1 377 2.3 BC016891
Ceacam1 CEA-related cell adhesion molecule 1 670 2.5 NM_011926
Ceacam2 CEA-related cell adhesion molecule 2 100 3.1 NM_007543
Ceacam2 CEA-related cell adhesion molecule 2 733 2.6 BC024320
Cp ceruloplasmin 232 2.1 BB332449
Ccl21a chemokine (C-C motif) ligand 21a (serine) 368 2.0 NM_011335
Ccl5 chemokine (C-C motif) ligand 5 34 6.0 NM_013653
Ccl8 chemokine (C-C motif) ligand 8 115 2.3 NM_021443
Ccr5 chemokine (C-C motif) receptor 5 73 2.6 D83648
Cxcl10 chemokine (C—X—C motif) ligand 10 162 2.2 NM_021274
Cxcl12 chemokine (C—X—C motif) ligand 12 1335 2.2 NM_013655
Cxcl14 chemokine (C—X—C motif) ligand 14 260 2.1 AF252873
Cxcl14 chemokine (C—X—C motif) ligand 14 124 2.4 AF252873
Cxcl9 chemokine (C—X—C motif) ligand 9 125 6.5 NM_008599
CRAD-L cis-retinol/3alpha hydroxysterol short-chain 2243 4.5 BC018263
dehydrogenase-like
C2ta class II transactivator 89 2.0 AF042158
C1qb complement component 1, q 363 2.8 NM_009777
subcomponent, beta polypeptide
C1qg complement component 1, q 185 4.0 NM_007574
subcomponent, gamma polypeptide
C1r complement component 1, r 148 2.8 BB558917
subcomponent
C1r complement component 1, r 382 3.1 NM_023143
subcomponent
C1s complement component 1, s 395 2.3 BC022123
subcomponent
C2 complement component 2 (within H-2S) 1215 2.6 NM_013484
Coro1a coronin, actin binding protein 1A 168 2.2 BB740218
Coro1a coronin, actin binding protein 1A 239 2.2 BC002136
Cugbp2 CUG triplet repeat, RNA binding protein 2 161 2.1 BB644164
Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 367 2.1 NM_009876
Cox8b cytochrome c oxidase, subunit VIIIb 47 6.0 NM_007751
Cyp4a10 cytochrome P450, family 4, subfamily a, 573 2.0 BC013476
polypeptide 10
Cyp4a14 cytochrome P450, family 4, subfamily a, 47 148.5 AI327006
polypeptide 14
Dach1 dachshund 1 (Drosophila) 91 2.0 BB522228
Dock10 dedicator of cytokinesis 10 145 2.6 BF715043
D10Bwg1379e DNA segment, Chr 10, Brigham & 25 3.9 BB125269
Women's Genetics 1379 expressed
D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, 953 4.9 AW554405
expressed
D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, 1414 3.4 BI655075
expressed
D3Bwg0562e DNA segment, Chr 3, Brigham & Women's 52 2.4 BQ175587
Genetics 0562 expressed
D3Bwg0562e DNA segment, Chr 3, Brigham & Women's 178 3.1 BB238462
Genetics 0562 expressed
D7Bwg0421e DNA segment, Chr 7, Brigham & Women's 64 2.0 AK017222
Genetics 0421 expressed
Duf6 DUF6 containing protein 112 2.2 BB758319
Edaradd EDAR (ectodysplasin-A receptor)- 28 3.1 NM_133643
associated death domain
Emr4 EGF-like module containing, mucin-like, 20 3.5 AF396935
hormone receptor-like sequence 4
Elovl2 elongation of very long chain fatty acids 951 2.3 NM_019423
(FEN1/Elo2, SUR4/Elo3, yeast)-like 2
Elovl6 ELOVL family member 6, elongation of 323 3.2 NM_130450
long chain fatty acids (yeast)
Enah enabled homolog (Drosophila) 81 2.1 AV329519
Ednra endothelin receptor type A 18 3.6 BC008277
Eva epithelial V-like antigen 371 2.0 BC015076
Eva epithelial V-like antigen 490 2.0 BC015076
AI481100 expressed sequence AI481100 365 5.2 NM_019440
AI788959 expressed sequence AI788959 914 2.8 BC028826
AI789751 expressed sequence AI789751 326 9.9 AI789751
AI987712 expressed sequence AI987712 92 28.2 AW554594
AU040377 expressed sequence AU040377 141 2.1 AV024806
AW111922 expressed sequence AW111922 361 8.0 BM239828
AW111922 expressed sequence AW111922 885 7.5 BM239828
AW413625 expressed sequence AW413625 80 2.7 NM_026640
Fabp7 fatty acid binding protein 7, brain 795 2.1 NM_021272
Facl2 fatty acid Coenzyme A ligase, long chain 2 5896 2.3 BC006692
Facl2 fatty acid Coenzyme A ligase, long chain 2 1417 2.1 BI413218
Fer1l3 fer-1-like 3, myoferlin (C. elegans) 208 1.9 BI555209
Fgl2 fibrinogen-like protein 2 114 2.5 BF136544
Foxd1 forkhead box D1 36 2.8 BB662927
Foxq1 forkhead box Q1 219 2.5 NM_008239
Foxq1 forkhead box Q1 142 3.8 AV009267
Gpr135 G protein-coupled receptor 135 45 2.9 AV221890
Gsto1 glutathione S-transferase omega 1 1328 2.1 AV003026
Gpm6b glycoprotein m6b 232 2.2 AK016567
Gzma granzyme A 68 3.6 NM_010370
Gc group specific component 554 6.0 AI195150
Gbp2 guanylate nucleotide binding protein 2 321 23.0 NM_010260
Gbp2 guanylate nucleotide binding protein 2 272 22.9 BE197524
Hck hemopoietic cell kinase 117 2.1 NM_010407
Hdgfrp3 hepatoma-derived growth factor, related 93 2.6 BB291880
protein 3
H2-Aa histocompatibility 2, class II antigen A, 2137 4.3 AF119253
alpha
H2-Aa histocompatibility 2, class II antigen A, 3501 4.3 BE688749
alpha
H2-Ab1 histocompatibility 2, class II antigen A, 421 8.2 M15848
beta 1
H2-Ab1 histocompatibility 2, class II antigen A, 950 7.9 NM_010379
beta 1
H2-Ab1 histocompatibility 2, class II antigen A, 659 10.9 M15848
beta 1
H2-Eb1 histocompatibility 2, class II antigen E beta 1760 3.7 NM_010382
H2-DMa histocompatibility 2, class II, locus DMa 261 9.0 NM_010386
H2-DMb1 histocompatibility 2, class II, locus Mb1 121 14.5 NM_010388
H2-DMb1 histocompatibility 2, class II, locus Mb1 159 15.2 BB734586
H2-DMb1 histocompatibility 2, class II, locus Mb1 116 8.9 NM_010387
H2-DMb1 histocompatibility 2, class II, locus Mb1 87 20.1 BB734586
H2-DMb1 histocompatibility 2, class II, locus Mb1 347 7.4 NM_010388
H2-K histocompatibility 2, K region 626 10.3 L23495
H2-T10 histocompatibility 2, T region locus 10 2355 2.3 NM_010395
H2-T23 histocompatibility 2, T region locus 23 2198 5.2 NM_010398
Hist1h2ae histone 1, H2ae 525 2.3 W91024
Hoxd3 homeo box D3 127 1.9 J03770
Hrasls3 HRAS like suppressor 3 504 6.9 BC024581
Hrasls3 HRAS like suppressor 3 372 7.1 BB404920
Hpgd hydroxyprostaglandin dehydrogenase 15 556 2.7 AV026552
(NAD)
9830126M18 hypothetical protein 9830126M18 113 2.0 BM224662
A330067P21 hypothetical protein A330067P21 65 2.0 BG085812
A330075D07 hypothetical protein A330075D07 34 2.7 BB193024
D630002G06 hypothetical protein D630002G06 712 6.1 AB056443
D630002G06 hypothetical protein D630002G06 650 5.4 AB056443
D630002G06 hypothetical protein D630002G06 136 3.6 NM_134256
D730019B10 hypothetical protein D730019B10 23 2.5 BB508669
MGC6357 hypothetical protein MGC6357 68 2.2 BB667558
li la-associated invariant chain 3790 4.3 BC003476
Idb3 inhibitor of DNA binding 3 1075 2.1 NM_008321
Idb4 inhibitor of DNA binding 4 175 2.1 BB306828
Idb4 inhibitor of DNA binding 4 1179 2.2 BB121406
Igf1 insulin-like growth factor 1 398 2.1 BG092677
Igfals insulin-like growth factor binding protein, 214 2.4 NM_008340
acid labile subunit
Itga6 integrin alpha 6 2198 2.0 BM935811
Itgax integrin alpha X 80 2.6 NM_021334
Igtp interferon gamma induced GTPase 905 5.6 NM_018738
Ifi1 interferon inducible protein 1 1151 3.8 NM_008326
Irf7 interferon regulatory factor 7 198 4.0 NM_016850
G1p2 interferon, alpha-inducible protein 112 3.3 AK019325
Ifit1 interferon-induced protein with 93 6.2 NM_008331
tetratricopeptide repeats 1
Ifit2 interferon-induced protein with 271 2.9 NM_008332
tetratricopeptide repeats 2
Il18bp interleukin 18 binding protein 122 12.2 AF110803
Kcnip2 Kv channel-interacting protein 2 94 2.8 AW490636
Kcnip2 Kv channel-interacting protein 2 28 2.8 AF439339
Kynu kynureninase (L-kynurenine hydrolase) 202 4.1 AV227891
Lrp8 low density lipoprotein receptor-related 84 2.8 BB750940
protein 8, apolipoprotein e receptor
Ly6e lymphocyte antigen 6 complex, locus E 1793 3.2 BM245572
Ly6f lymphocyte antigen 6 complex, locus F 24 7.1 NM_008530
— M. musculus mRNA for testis-specific 4515 2.1 AV148480
thymosin beta-10
Mpeg1 macrophage expressed gene 1 402 4.5 L20315
Mme membrane metallo endopeptidase 2038 2.0 AV174022
Ms4a11 membrane-spanning 4-domains, subfamily 50 2.3 NM_026835
A, member 11
Ms4a4d membrane-spanning 4-domains, subfamily 96 2.6 NM_025658
A, member 4D
Ms4a6b membrane-spanning 4-domains, subfamily 126 2.8 NM_027209
A, member 6B
— MHC I = H-2Kd homolog {alternatively 435 10.0 S70184
spliced, deletion of exon 3} [mice, DBA/2,
L1210 lymphoma, mRNA Mutant, 855 nt]
Mmd monocyte to macrophage differentiation- 662 2.3 BC021914
associated
— Mus musculus 0 day neonate head cDNA, 420 2.5 BB109391
RIKEN full-length enriched library,
clone: 4833430O13 product: unknown EST,
full insert sequence
— Mus musculus 0 day neonate kidney 39 2.3 BB500101
cDNA, RIKEN full-length enriched library,
clone: D630024M22 product: unclassifiable,
full insert sequence
— Mus musculus 0 day neonate kidney 153 2.1 BB820846
cDNA, RIKEN full-length enriched library,
clone: D630033M22 product: hypothetical
protein, full insert sequence
— Mus musculus 0 day neonate kidney 54 2.9 BB504342
cDNA, RIKEN full-length enriched library,
clone: D630047M14 product: unclassifiable,
full insert sequence
— Mus musculus 0 day neonate lung cDNA, 70 2.0 BI452538
RIKEN full-length enriched library,
clone: E030022N22 product: unclassifiable,
full insert sequence
— Mus musculus 0 day neonate thymus 112 2.7 AK020789
cDNA, RIKEN full-length enriched library,
clone: A430110A21 product: unclassifiable,
full insert sequence
— Mus musculus 10 days neonate 38 2.7 BM201103
cerebellum cDNA, RIKEN full-length
enriched library, clone: B930059K21
product: unknown EST, full insert sequence
— Mus musculus 12 days embryo spinal 56 2.0 BB454099
ganglion cDNA, RIKEN full-length enriched
library, clone: D130028L22
product: unclassifiable, full insert sequence
— Mus musculus 16 days embryo head 110 2.3 BB208251
cDNA, RIKEN full-length enriched library,
clone: C130051K14 product: unknown EST,
full insert sequence
— Mus musculus 16 days embryo head 71 2.6 BB374879
cDNA, RIKEN full-length enriched library,
clone: C130077H22 product: unclassifiable,
full insert sequence
— Mus musculus 16 days neonate 128 2.1 AV118079
cerebellum cDNA, RIKEN full-length
enriched library, clone: 9630032E14
product: unknown EST, full insert sequence
— Mus musculus 16 days neonate thymus 56 2.4 BB162048
cDNA, RIKEN full-length enriched library,
clone: A130086M19 product: unknown EST,
full insert sequence
— Mus musculus 18-day embryo whole body 157 2.2 BM730637
cDNA, RIKEN full-length enriched library,
clone: 1110059G02 product: unclassifiable,
full insert sequence
— Mus musculus 2 days pregnant adult 55 2.2 BB053468
female oviduct cDNA, RIKEN full-length
enriched library, clone: E230038I17
product: unknown EST, full insert sequence
— Mus musculus 3 days neonate thymus 172 2.8 BI151331
cDNA, RIKEN full-length enriched library,
clone: A630040D01 product: unknown EST,
full insert sequence
— Mus musculus 4 days neonate male 87 2.0 BB326079
adipose cDNA, RIKEN full-length enriched
library, clone: B430203I24
product: unknown EST, full insert sequence
— Mus musculus 6 days neonate head 85 2.1 AK017417
cDNA, RIKEN full-length enriched library,
clone: 5430440L12 product: unknown EST,
full insert sequence
— Mus musculus 7 days embryo whole body 124 2.2 BB408240
cDNA, RIKEN full-length enriched library,
clone: C430005H19 product: unknown EST,
full insert sequence
— Mus musculus adult male bone cDNA, 55 2.3 BB134628
RIKEN full-length enriched library,
clone: 9830116N24 product: unclassifiable,
full insert sequence
— Mus musculus adult male corpora 64 2.6 AI323288
quadrigemina cDNA, RIKEN full-length
enriched library, clone: B230339M22
product: inhibitor of DNA binding 4, full
insert sequence
— Mus musculus adult male medulla 26 2.2 AV332226
oblongata cDNA, RIKEN full-length
enriched library, clone: 6330531L09
product: unknown EST, full insert sequence
— Mus musculus adult male olfactory brain 26 1.9 AV237721
cDNA, RIKEN full-length enriched library,
clone: 6430566E03 product: unknown EST,
full insert sequence
— Mus musculus Corpos mRNA, 3′ 59 2.2 BM220939
untranslated region
— Mus musculus NOD-derived CD11c +ve 223 2.1 AK004894
dendritic cells cDNA, RIKEN full-length
enriched library, clone: F630107D10
product: similar to UBIQUITIN-
ACTIVATING ENZYME E1 [Homo
sapiens], full insert sequence
— Mus musculus similar to Aldo-keto 907 2.1 BG073853
reductase family 1 member C13
(LOC238465), mRNA
— Mus musculus similar to hypothetical 716 2.5 BM243674
protein (LOC243374), mRNA
— Mus musculus similar to hypothetical 25 2.4 BE197771
protein FLJ31208 (LOC225602), mRNA
— Mus musculus transcribed sequence 31 3.5 AI790337
— Mus musculus transcribed sequence with 47 3.3 BG063622
strong similarity to protein sp: P00722 (E. coli)
BGAL_ECOLI Beta-galactosidase
(Lactase)
— Mus musculus transcribed sequence with 44 4.7 BB210623
weak similarity to protein ref: NP_036400.1
(H. sapiens) similar to vaccinia virus
HindIII K4L ORF [Homo sapiens]
— Mus musculus transcribed sequence with 191 45.8 BM241485
weak similarity to protein sp: P32456
(H. sapiens) GBP2_HUMAN Interferon-
induced guanylate-binding protein 2
(Guanine nucleotide-binding protein 2)
— Mus musculus transcribed sequences 35 2.5 BB460538
— Mus musculus transcribed sequences 90 2.1 BB485280
— Mus musculus transcribed sequences 46 2.0 BM218007
— Mus musculus transcribed sequences 87 3.4 AV277444
— Mus musculus transcribed sequences 438 4.5 BE688358
— Mus musculus transcribed sequences 182 2.1 AW492955
— Mus musculus transcribed sequences 58 4.5 BI134319
— Mus musculus transcribed sequences 91 2.0 BB497148
— Mus musculus transcribed sequences 63 2.4 BG069383
— Mus musculus transcribed sequences 67 2.1 BM220820
— Mus musculus transcribed sequences 25 2.2 BB553888
— Mus musculus transcribed sequences 18 2.2 BB767194
— Mus musculus transcribed sequences 44 2.0 BM730703
— Mus musculus transcribed sequences 102 1.9 BG068971
— Mus musculus transcribed sequences 339 27.6 BG092512
— Mus musculus transcribed sequences 130 2.0 AW546127
— Mus musculus transcribed sequences 72 2.3 AW543171
— Mus musculus transcribed sequences 150 2.1 BI664122
— Mus musculus transcribed sequences 193 2.0 AV291009
— Mus musculus transcribed sequences 54 2.0 AU041975
— Mus musculus transcribed sequences 95 2.0 AV352204
— Mus musculus transcribed sequences 20 2.1 BB043509
— Mus musculus transcribed sequences 217 2.0 BM119402
— Mus musculus transcribed sequences 32 2.5 AV300631
— Mus musculus transcribed sequences 82 4.6 BG067157
— Mus musculus transcribed sequences 115 2.2 AW111920
— Mus musculus transcribed sequences 35 3.5 BM225081
— Mus musculus transcribed sequences 133 2.0 AW556334
— Mus musculus transcribed sequences 27 3.0 AI118114
— Mus musculus transcribed sequences 18 3.1 BB520952
— Mus musculus transcribed sequences 142 2.2 AV264768
— Mus musculus, clone IMAGE: 4507681, 32 3.0 BG071655
mRNA
Mll myeloid/lymphoid or mixed-lineage 128 2.1 AK017541
leukemia
Npnt nephronectin 1459 2.0 AA223007
Npnt nephronectin BB433705
Ntf3 neurotrophin 3 49 3.3 NM_008742
Odz3 odd Oz/ten-m homolog 3 (Drosophila) 9 3.2 BB472509
Olfr56 olfactory receptor 56 336 3.4 NM_008330
Padi2 peptidyl arginine deiminase, type II 110 3.0 NM_008812
Ppicap peptidylprolyl isomerase C-associated 1079 3.2 NM_011150
protein
Pte2a peroxisomal acyl-CoA thioesterase 2A 780 2.7 NM_134246
Pck1 phosphoenolpyruvate carboxykinase 1, 46 6.8 BB225177
cytosolic
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 64 3.0 BI684288
Pigr polymeric immunoglobulin receptor 3030 2.1 AV027632
Kcnk1 potassium channel, subfamily K, member 1 708 4.0 AU043100
Prickle1 prickle like 1 (Drosophila) 144 2.3 BC022643
Prickle1 prickle like 1 (Drosophila) 40 2.9 BE992966
Pdcd1lg1 programmed cell death 1 ligand 1 73 4.4 NM_021893
Prom1 prominin 1 2598 2.7 NM_008935
Psmb10 proteasome (prosome, macropain) 525 3.2 NM_013640
subunit, beta type 10
Psmb8 proteosome (prosome, macropain) 17 5.1 AV068122
subunit, beta type 8 (large multifunctional
protease 7)
Psmb8 proteosome (prosome, macropain) 461 9.9 NM_010724
subunit, beta type 8 (large multifunctional
protease 7)
Psmb9 proteosome (prosome, macropain) 298 4.5 NM_013585
subunit, beta type 9 (large multifunctional
protease 2)
Arhgef6 Rac/Cdc42 guanine nucleotide exchange 142 2.8 BM246754
factor (GEF) 6
Rai2 retinoic acid induced 2 59 2.0 BB770528
1110004C05Rik RIKEN cDNA 1110004C05 gene 3701 2.3 BC010291
1110036C17Rik RIKEN cDNA 1110036C17 gene 622 2.7 BC027285
1110036O03Rik RIKEN cDNA 1110036O03 gene 115 2.0 BE951265
1110063G11Rik RIKEN cDNA 1110063G11 gene 81 2.0 AK004359
1190005J19Rik RIKEN cDNA 1190005J19 gene 31 2.0 NM_007819
1200015N20Rik RIKEN cDNA 1200015N20 gene 39 2.2 BB461323
1600020H07Rik RIKEN cDNA 1600020H07 gene 1301 2.7 NM_019975
1700003F17Rik RIKEN cDNA 1700003F17 gene 64 2.9 AV220213
1700007J06Rik RIKEN cDNA 1700007J06 gene 27 2.2 AK005720
1700019D03Rik RIKEN cDNA 1700019D03 gene 20 2.4 AK006110
1810037B05Rik RIKEN cDNA 1810037B05 gene 50 3.0 AK007714
2010204K13Rik RIKEN cDNA 2010204K13 gene 249 2.3 NM_023450
2310007B03Rik RIKEN cDNA 2310007B03 gene 78 2.3 AK009193
2310008H04Rik RIKEN cDNA 2310008H04 gene 246 5.7 BC026877
2310015I10Rik RIKEN cDNA 2310015I10 gene 269 5.7 BC008532
2310022A04Rik RIKEN cDNA 2310022A04 gene 327 2.0 AK007542
2310035M22Rik RIKEN cDNA 2310035M22 gene 44 2.2 NM_025863
2310046K10Rik RIKEN cDNA 2310046K10 gene 63 2.2 AK017174
2310046K10Rik RIKEN cDNA 2310046K10 gene 106 2.1 BF020640
2310061N23Rik RIKEN cDNA 2310061N23 gene 219 4.2 AY090098
2410041A17Rik RIKEN cDNA 2410041A17 gene 556 3.4 NM_133348
2510038N07Rik RIKEN cDNA 2510038N07 gene 161 2.5 AW208668
2610030H06Rik RIKEN cDNA 2610030H06 gene 510 2.3 BB429625
2700038M07Rik RIKEN cDNA 2700038M07 gene 786 2.0 BC019601
2810002E22Rik RIKEN cDNA 2810002E22 gene 543 2.2 NM_133859
2810030E01Rik RIKEN cDNA 2810030E01 gene 76 2.1 BB255999
3300001H21Rik RIKEN cDNA 3300001H21 gene 106 2.3 NM_027334
4631422C05Rik RIKEN cDNA 4631422C05 gene 716 1.9 BI648645
4930513H15Rik RIKEN cDNA 4930513H15 gene 49 2.4 AK017117
4931406H21Rik RIKEN cDNA 4931406H21 gene 75 2.0 BG076071
4931408A02Rik RIKEN cDNA 4931408A02 gene 58 3.7 AK016443
4933402B14Rik RIKEN cDNA 4933402B14 gene 45 2.2 AV278444
5430425C04Rik RIKEN cDNA 5430425C04 gene 44 2.9 AK017334
5830458K16Rik RIKEN cDNA 5830458K16 gene 525 2.6 BC024872
6330407A03Rik RIKEN cDNA 6330407A03 gene 60 2.2 AW519657
6720477E09Rik RIKEN cDNA 6720477E09 gene 132 2.3 BB053506
9230117N10Rik RIKEN cDNA 9230117N10 gene 222 2.2 NM_133775
9330174J19Rik RIKEN cDNA 9330174J19 gene 39 4.4 BE687891
A330021E22Rik RIKEN cDNA A330021E22 gene 52 2.0 BB561281
A830021K08Rik RIKEN cDNA A830021K08 gene 825 2.4 BB291885
A930021H16Rik RIKEN cDNA A930021H16 gene 54 2.1 BB513585
B830010L13Rik RIKEN cDNA B830010L13 gene 144 2.6 BB333374
C330012H03Rik RIKEN cDNA C330012H03 gene 69 2.0 BB098431
D430019H16Rik RIKEN cDNA D430019H16 gene 57 2.5 BM116882
D730043B02Rik RIKEN cDNA D730043B02 gene 104 2.2 AK021336
E530005C20Rik RIKEN cDNA E530005C20 gene 56 2.0 BB662566
Robo2 roundabout homolog 2 (Drosophila) 22 2.3 BB366379
Sall1 sal-like 1 (Drosophila) 687 2.1 BB739342
Sema3e sema domain, immunoglobulin domain 60 2.0 NM_011348
(Ig), short basic domain, secreted,
(semaphorin) 3E
Serpina10 serine (or cysteine) proteinase inhibitor, 211 7.6 BC018416
clade A (alpha-1 antiproteinase,
antitrypsin), member 10
Serpina3g serine (or cysteine) proteinase inhibitor, 92 4.5 BC002065
clade A, member 3G
Serpinb9 serine (or cysteine) proteinase inhibitor, 323 2.1 BE686716
clade B, member 9
Serping1 serine (or cysteine) proteinase inhibitor, 2372 3.8 NM_009776
clade G, member 1
Stard13 serologically defined colon cancer antigen 151 2.0 BB667840
13
Stat1 signal transducer and activator of 171 3.8 AW214029
transcription 1
Stat1 signal transducer and activator of 915 2.7 AW214029
transcription 1
Stat1 signal transducer and activator of 808 2.8 AW214029
transcription 1
Slamf8 SLAM family member 8 27 3.3 BC024587
Slc7a12 solute carrier family 7 (cationic amino acid 290 29.4 NM_080852
transporter, y+ system), member 12
Slco2a1 solute carrier organic anion transporter 349 2.1 NM_033314
family, member 2a1
Stab2 stabilin 2 230 1.9 NM_138673
Scd1 stearoyl-Coenzyme A desaturase 1 2255 5.6 NM_009127
Scd1 stearoyl-Coenzyme A desaturase 1 389 3.5 NM_009127
Socs2 suppressor of cytokine signaling 2 478 3.7 NM_007706
Socs2 suppressor of cytokine signaling 2 354 4.7 NM_007706
Syt13 synaptotagmin 13 37 3.3 BB244585
Tapbp TAP binding protein 2304 3.5 AF043943
Tbx3 T-box 3 58 2.1 BB728182
Tgtp T-cell specific GTPase 1220 8.9 NM_011579
Thoc1 THO complex 1 33 2.2 BB647938
Thbs1 thrombospondin 1 727 2.1 AI385532
Tmsb10 thymosin, beta 10 941 2.4 NM_025284
Top2a topoisomerase (DNA) II alpha 142 2.0 BM211413
Tle2 transducin-like enhancer of split 2, 150 2.1 AU067681
homolog of Drosophila E(spl)
Tgfbi transforming growth factor, beta induced 294 2.3 NM_009369
Tgfbi transforming growth factor, beta induced 229 2.5 NM_009369
Tm4sf3 transmembrane 4 superfamily member 3 124 2.1 C76990
Tap1 transporter 1, ATP-binding cassette, sub- 127 5.7 AW048052
family B (MDR/TAP)
Tmlhe trimethyllysine hydroxylase, epsilon 66 1.9 BC005497
Tpm2 tropomyosin 2, beta 307 2.1 BC024358
Tubb2 tubulin, beta 2 969 2.3 BC003475
Tnfsf13b tumor necrosis factor (ligand) superfamily, 101 2.4 NM_033622
member 13b
Arts1 type 1 tumor necrosis factor receptor 444 2.3 NM_030711
shedding aminopeptidase regulator
Arts1 type 1 tumor necrosis factor receptor 221 2.8 AV287655
shedding aminopeptidase regulator
Ubd ubiquitin D 121 11.5 NM_023137
Utx ubiquitously transcribed tetratricopeptide 22 2.6 BB306686
repeat gene, X chromosome
Vcam1 vascular cell adhesion molecule 1 268 2.6 BB250384
Was Wiskott-Aldrich syndrome homolog 25 3.8 NM_009515
(human)
Xdh xanthine dehydrogenase 167 4.7 AV286265
Zbp1 Z-DNA binding protein 1 49 5.1 AK008179
Zdhhc6 zinc finger, DHHC domain containing 6 70 2.0 BB251023
TABLE 2
Rejection-induced transcripts (RITs)
WT D5
Gene Symbol NCBA vs
Affymetrix Common Gene Title Affymetrix Raw NCBA Genbank
0610009C03Rik 0610009C03Rik RIKEN cDNA 0610009C03 gene 538 2.0 AK002371
0610025L06Rik 0610025L06Rik RIKEN cDNA 0610025L06 gene 277 5.2 AK012581
0610033I05Rik 0610033I05Rik RIKEN cDNA 0610033I05 gene 407 3.0 BC003333
0610037M15Rik 0610037M15Rik RIKEN cDNA 0610037M15 gene 169 15.6 BG916808
0610039P13Rik 0610039P13Rik RIKEN cDNA 0610039P13 gene 141 3.4 BC021548
— 0910001A06Rik Mus musculus 3 days neonate thymus 60 4.2 BB229269
cDNA, RIKEN full-length enriched library,
clone: A630020J17 product: unknown
EST, full insert sequence
0910001A06Rik 0910001A06Rik RIKEN cDNA 0910001A06 gene 663 6.7 BC011343
0910001A06Rik 0910001A06Rik RIKEN cDNA 0910001A06 gene 63 2.3 AV033641
1100001H23Rik 1100001H23Rik RIKEN cDNA 1100001H23 gene 988 4.4 NM_025806
1100001I19Rik 1100001I19Rik RIKEN cDNA 1100001I19 gene 288 2.1 BM119324
1100001I19Rik 1100001I19Rik RIKEN cDNA 1100001I19 gene 219 2.8 BE949451
1110006O17Rik 1110006O17Rik RIKEN cDNA 1110006O17 gene 199 5.1 BB736636
1110007F12Rik 1110007F12Rik RIKEN cDNA 1110007F12 gene 30 4.0 BB765808
1110007F12Rik 1110007F12Rik RIKEN cDNA 1110007F12 gene 1154 3.0 BC020080
— 1110007H17Rik Mus musculus 0 day neonate lung cDNA, 97 2.1 BI466783
RIKEN full-length enriched library,
clone: E030022F06 product: inferred:
exchange factor for ARF6 {Rattus
norvegicus}, full insert sequence
1110008F13Rik 1110008F13Rik RIKEN cDNA 1110008F13 gene 16 6.7 AV316605
1110013L07Rik 1110013L07Rik RIKEN cDNA 1110013L07 gene 165 3.0 BB765852
— 1110033M05Rik Mus musculus transcribed sequences 34 2.1 BM220862
1200002N14Rik 1200002N14Rik RIKEN cDNA 1200002N14 gene 470 4.3 BC021433
1200008O12Rik 1200008O12Rik RIKEN cDNA 1200008O12 gene 44 16.3 AK004655
1200009I06Rik 1200009I06Rik RIKEN cDNA 1200009I06 gene 270 2.0 AK005443
1200013B08Rik 1200013B08Rik RIKEN cDNA 1200013B08 gene 183 8.3 AK004734
1300002K09Rik 1300002K09Rik RIKEN cDNA 1300002K09 gene 141 3.6 AV222559
1500001L15Rik 1500001L15Rik RIKEN cDNA 1500001L15 gene 921 2.1 BB559925
1500002B03Rik 1500002B03Rik RIKEN cDNA 1500002B03 gene 175 2.4 AK005105
1500004A08Rik 1500004A08Rik RIKEN cDNA 1500004A08 gene 219 2.3 BB030508
1500031M22Rik 1500031M22Rik RIKEN cDNA 1500031M22 gene 119 2.1 AK015145
1700013H19Rik 1700013H19Rik RIKEN cDNA 1700013H19 gene 144 2.3 AK005954
1700022C02Rik 1700022C02Rik RIKEN cDNA 1700022C02 gene 24 3.9 AK014919
1700025G04Rik 1700025G04Rik RIKEN cDNA 1700025G04 gene 110 2.0 AW557527
1700001M19Rik 1700029K01Rik RIKEN cDNA 1700001M19 gene 59 2.0 BG075808
1700047I17Rik 1700047I17Rik RIKEN cDNA 1700047I17 gene 65 3.8 BB824055
1700061I17Rik 1700061I17Rik RIKEN cDNA 1700061I17 gene 27 2.5 AK006854
— 1700091G21Rik Mus musculus 16 days neonate thymus 97 4.3 BG075562
cDNA, RIKEN full-length enriched library,
clone: A130042K22 product: unknown
EST, full insert sequence
1700095N21Rik 1700095N21Rik RIKEN cDNA 1700095N21 gene 151 2.3 NM_029682
— 1700097N02Rik Mus musculus adult male testis cDNA, 16 5.0 AA266367
RIKEN full-length enriched library,
clone: 1700122G02 product: unknown
EST, full insert sequence
1810019A08Rik 1810019A08Rik RIKEN cDNA 1810019A08 gene 80 5.1 AK007540
1810033B17Rik 1810033B17Rik RIKEN cDNA 1810033B17 gene 38 6.4 BB533148
1810037B05Rik 1810037B05Rik RIKEN cDNA 1810037B05 gene 50 3.1 AK007714
1810049K24Rik 1810049K24Rik RIKEN cDNA 1810049K24 gene 484 2.4 BB558800
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 gene 40 5.0 AK007856
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 gene 45 5.4 BB397062
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 gene 99 4.5 BB259628
— 1810057P16Rik Mus musculus 10 days neonate cortex 94 2.6 BB275943
cDNA, RIKEN full-length enriched library,
clone: A830095F23 product: unknown
EST, full insert sequence
1810062O14Rik 1810062O14Rik RIKEN cDNA 1810062O14 gene 99 7.4 AV060417
2010012C16Rik 2010012C16Rik RIKEN cDNA 2010012C16 gene 187 3.0 AK006303
— 2010012F05Rik Mus musculus adult male colon cDNA, 54 2.2 AK018542
RIKEN full-length enriched library,
clone: 9030607L20 product: weakly similar
to MHC CLASS I T7 ANTIGEN
(FRAGMENT) [Mus musculus], full insert
sequence
2010106G01Rik 2010106G01Rik RIKEN cDNA 2010106G01 gene 1397 2.0 NM_023220
2010109K11Rik 2010109K11Rik RIKEN cDNA 2010109K11 gene 256 3.2 BB174749
2010308M01Rik 2010308M01Rik RIKEN cDNA 2010308M01 gene 163 2.3 BC008266
A430106J12Rik 2010316F05Rik RIKEN cDNA A430106J12 gene 41 3.5 BB228331
2200002D01Rik 2200002D01Rik RIKEN cDNA 2200002D01 gene 189 2.3 AK008617
2210421G13Rik 2210421G13Rik RIKEN cDNA 2210421G13 gene 19 9.3 AV081797
2310014H01Rik 2310014H01Rik RIKEN cDNA 2310014H01 gene 331 3.3 AK009340
2310015N21Rik 2310015N21Rik RIKEN cDNA 2310015N21 gene 300 2.9 AK009372
2310031L18Rik 2310031L18Rik RIKEN cDNA 2310031L18 gene 76 3.4 BC027435
2310032F03Rik 2310032F03Rik RIKEN cDNA 2310032F03 gene 36 7.7 BE633038
2310043D08Rik 2310043D08Rik RIKEN cDNA 2310043D08 gene 28 5.6 BF021255
— 2310047A01Rik Mus musculus similar to hypothetical 81 2.0 BB813478
protein FLJ90798 (LOC382857), mRNA
2310047O13Rik 2310047O13Rik RIKEN cDNA 2310047O13 gene 18 2.9 AW554864
2310061F22Rik 2310061F22Rik RIKEN cDNA 2310061F22 gene 734 2.1 BB253397
2310067E08Rik 2310067E08Rik RIKEN cDNA 2310067E08 gene 246 2.5 BF168366
2310075C12Rik 2310075C12Rik RIKEN cDNA 2310075C12 gene 850 2.2 NM_133739
2400006A19Rik 2400006A19Rik RIKEN cDNA 2400006A19 gene 288 7.5 BC006869
2410002M20Rik 2410002M20Rik RIKEN cDNA 2410002M20 gene 637 2.2 BM209793
2410002O22Rik 2410002O22Rik RIKEN cDNA 2410002O22 gene 48 2.4 AK012141
2410004I17Rik 2410004I17Rik RIKEN cDNA 2410004I17 gene 26 6.8 AK010391
— 2410006H16Rik Mus musculus ES cells cDNA, RIKEN 359 2.3 AA939619
full-length enriched library,
clone: 2410006H16 product: unknown
EST, full insert sequence
2410012M04Rik 2410012M04Rik RIKEN cDNA 2410012M04 gene 58 2.0 BG229936
B230342M21Rik 2410024N18Rik RIKEN cDNA B230342M21 gene 40 3.2 AK010587
2410030K01Rik 2410030K01Rik RIKEN cDNA 2410030K01 gene 130 2.4 BF577722
— 2410129E14Rik Mus musculus transcribed sequence with 374 3.2 AA986082
strong similarity to protein
ref: NP_001060.1 (H. sapiens) tubulin,
beta polypeptide [Homo sapiens]
2600005O03Rik 2600005O03Rik RIKEN cDNA 2600005O03 gene 22 5.5 AK011162
— 2610002F03Rik Mus musculus ES cells cDNA, RIKEN 24 3.7 AV011566
full-length enriched library,
clone: 2410046H18 product: unknown
EST, full insert sequence
2610028H07Rik 2610028H07Rik RIKEN cDNA 2610028H07 gene 365 2.9 BC006738
2610029G23Rik 2610029G23Rik RIKEN cDNA 2610029G23 gene 582 2.0 NM_026312
— 2610036L11Rik Mus musculus adult male testis cDNA, 68 3.7 BF453953
RIKEN full-length enriched library,
clone: 1700015C21 product: unknown
EST, full insert sequence
2610039C10Rik 2610039C10Rik RIKEN cDNA 2610039C10 gene 153 3.9 AK012533
2610040C18Rik 2610040C18Rik RIKEN cDNA 2610040C18 gene 25 4.3 AU043467
2610042L04Rik 2610042L04Rik RIKEN cDNA 2610042L04 gene 203 5.0 BM195235
2610042L04Rik 2610042L04Rik RIKEN cDNA 2610042L04 gene 337 4.9 BM195235
2610206B13Rik 2610206B13Rik RIKEN cDNA 2610206B13 gene 105 2.6 AK011896
2610208M17Rik 2610208M17Rik RIKEN cDNA 2610208M17 gene 227 2.8 BI104583
2610208M17Rik 2610208M17Rik RIKEN cDNA 2610208M17 gene 610 3.5 BI104583
2610208M17Rik 2610208M17Rik RIKEN cDNA 2610208M17 gene 114 3.1 BQ129438
2610300B10Rik 2610300B10Rik RIKEN cDNA 2610300B10 gene 87 2.6 BB538449
— 2610307O08Rik — 47 18.7 AV300716
2610307O08Rik 2610307O08Rik RIKEN cDNA 2610307O08 gene 246 6.8 AK012006
— 2610318C08Rik Mus musculus adult male small intestine 156 2.5 AA197362
cDNA, RIKEN full-length enriched library,
clone: 2010016H04 product: unknown
EST, full insert sequence
2610318N02Rik 2610318N02Rik RIKEN cDNA 2610318N02 gene 21 7.0 AK012048
2610510H01Rik 2610510H01Rik RIKEN cDNA 2610510H01 gene 214 2.1 AV122997
2610510H01Rik 2610510H01Rik RIKEN cDNA 2610510H01 gene 253 2.4 AV122997
2610510J17Rik 2610510J17Rik RIKEN cDNA 2610510J17 gene 155 3.0 BM230253
2700019D07Rik 2700019D07Rik RIKEN cDNA 2700019D07 gene 369 2.7 BM937429
— 2700038G22Rik Mus musculus adult retina cDNA, RIKEN 141 2.3 AK012332
full-length enriched library,
clone: A930033E24
product: unclassifiable, full insert
sequence
2700049P18Rik 2700049P18Rik RIKEN cDNA 2700049P18 gene 73 2.4 AV127670
2810026P18Rik 2810026P18Rik RIKEN cDNA 2810026P18 gene 209 3.1 AK012825
2810047L02Rik 2810047L02Rik RIKEN cDNA 2810047L02 gene 19 8.8 AV270035
2810052M02Rik 2810052M02Rik RIKEN cDNA 2810052M02 gene 99 4.6 NM_023320
2810406C15Rik 2810406C15Rik RIKEN cDNA 2810406C15 gene 103 5.4 BC025460
2810417H13Rik 2810417H13Rik RIKEN cDNA 2810417H13 gene 165 23.4 AK017673
2810417H13Rik 2810417H13Rik RIKEN cDNA 2810417H13 gene 44 17.7 AK017673
2810418N01Rik 2810418N01Rik RIKEN cDNA 2810418N01 gene 115 3.2 AK013116
A330067P21 2810453L12Rik hypothetical protein A330067P21 65 2.2 BG085812
2810457I06Rik 2810457I06Rik RIKEN cDNA 2810457I06 gene 186 2.6 AK013361
2810457I06Rik 2810457I06Rik RIKEN cDNA 2810457I06 gene 180 3.0 AW045947
6720435I21Rik 2810474O19Rik RIKEN cDNA 6720435I21 gene 860 2.2 AA509870
2900024D24Rik 2900024D24Rik RIKEN cDNA 2900024D24 gene 48 10.4 BB134696
2900024D24Rik 2900024D24Rik RIKEN cDNA 2900024D24 gene 82 4.3 AI449126
Krc 2900056N03Rik kappa B and Rss recognition component 88 5.0 BB164127
3110010F15Rik 3110010F15Rik RIKEN cDNA 3110010F15 gene 173 2.6 BF320755
3110010F15Rik 3110010F15Rik RIKEN cDNA 3110010F15 gene 307 2.0 BF320755
3110037K17Rik 3110037K17Rik RIKEN cDNA 3110037K17 gene 58 21.7 AK014135
3300001P08Rik 3300001P08Rik RIKEN cDNA 3300001P08 gene 64 2.4 BM213851
4432406C08Rik 4432406C08Rik RIKEN cDNA 4432406C08 gene 16 10.0 BM247465
4631422C13Rik 4631422C13Rik RIKEN cDNA 4631422C13 gene 27 2.8 BB154962
AW413625 4632417K18Rik expressed sequence AW413625 80 15.2 NM_026640
4632428N05Rik 4632428N05Rik RIKEN cDNA 4632428N05 gene 139 2.6 BC003967
4632434I11Rik 4632434I11Rik RIKEN cDNA 4632434I11 gene 20 2.8 BB463610
4732429D16Rik 4732429D16Rik RIKEN cDNA 4732429D16 gene 130 2.0 BC019814
4732490P18Rik 4732490P18Rik RIKEN cDNA 4732490P18 gene 31 2.1 BB009703
— 4833403J16Rik Mus musculus 0 day neonate head 41 2.5 AK014653
cDNA, RIKEN full-length enriched library,
clone: 4833403J16 product: unknown
EST, full insert sequence
4833427B12Rik 4833427B12Rik RIKEN cDNA 4833427B12 gene 24 7.7 AW488914
4921501M20Rik 4921501M20Rik RIKEN cDNA 4921501M20 gene 46 3.5 AF361364
— 4921511E18Rik Mus musculus adult male testis cDNA, 107 2.2 AK014868
RIKEN full-length enriched library,
clone: 4921511E18
product: unclassifiable, full insert
sequence
4930427A07Rik 4930427A07Rik RIKEN cDNA 4930427A07 gene 58 2.9 BE951637
4930477M19 4930477M19 hypothetical protein 4930477M19 66 2.4 BB017021
4930503L19Rik 4930503L19Rik RIKEN cDNA 4930503L19 gene 42 3.5 AI450962
4930503L19Rik 4930503L19Rik RIKEN cDNA 4930503L19 gene 27 6.4 AI450962
4930547N16Rik 4930547N16Rik RIKEN cDNA 4930547N16 gene 10 6.9 BM205349
4930547N16Rik 4930547N16Rik RIKEN cDNA 4930547N16 gene 25 3.5 BM877490
4930553M18Rik 4930553M18Rik RIKEN cDNA 4930553M18 gene 83 2.1 BG065617
— 4930571N24Rik Mus musculus transcribed sequence with 20 3.5 BE687174
moderate similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
4930579G24Rik 4930579G24Rik RIKEN cDNA 4930579G24 gene 99 3.0 BB821996
4931400A14Rik 4931400A14Rik RIKEN cDNA 4931400A14 gene 533 2.8 AK016419
— 4933412E12Rik Mus musculus 13 days embryo heart 197 2.2 AK016788
cDNA, RIKEN full-length enriched library,
clone: D330011B05 product: unknown
EST, full insert sequence
4933426L22Rik 4933426L22Rik RIKEN cDNA 4933426L22 gene 88 3.8 BB361436
4933426L22Rik 4933426L22Rik RIKEN cDNA 4933426L22 gene 40 5.6 BB667247
4933430F08Rik 4933430F08Rik RIKEN cDNA 4933430F08 gene 31 37.4 AK016990
4933431N12Rik 4933431N12Rik RIKEN cDNA 4933431N12 gene 38 4.1 BE853276
5033406L14Rik 5033406L14Rik RIKEN cDNA 5033406L14 gene 101 3.1 BB667600
— 5033413D16Rik Mus musculus 0 day neonate eyeball 144 2.4 AK017164
cDNA, RIKEN full-length enriched library,
clone: E130011D04 product: unknown
EST, full insert sequence
— 5230400M03Rik Mus musculus adult male xiphoid 57 2.9 BB312292
cartilage cDNA, RIKEN full-length
enriched library, clone: 5230400M03
product: unclassifiable, full insert
sequence
A630029F06 5330417K06Rik hypothetical protein A630029F06 182 3.0 BB023868
5430427O19Rik 5430427O19Rik RIKEN cDNA 5430427O19 gene 23 7.3 AI645098
5430435G22Rik 5430435G22Rik RIKEN cDNA 5430435G22 gene 53 7.4 BB128517
— 5430437J10Rik Mus musculus, clone IMAGE: 5356629, 12 4.9 BF227338
mRNA
— 5730405O12Rik Mus musculus 0 day neonate eyeball 19 3.1 AK017499
cDNA, RIKEN full-length enriched library,
clone: E130007N07
product: unclassifiable, full insert
sequence
5730466H23Rik 5730466H23Rik RIKEN cDNA 5730466H23 gene 26 2.1 BB079695
— 5730507H05Rik Mus musculus adult male hypothalamus 25 10.1 BB702347
cDNA, RIKEN full-length enriched library,
clone: A230105F24 product: hypothetical
protein, full insert sequence
5730508B09Rik 5730508B09Rik RIKEN cDNA 5730508B09 gene 179 3.5 AK017758
5730508B09Rik 5730508B09Rik RIKEN cDNA 5730508B09 gene 47 11.2 C80506
— 5730601F06Rik Mus musculus 16 days embryo head 71 2.2 BB374879
cDNA, RIKEN full-length enriched library,
clone: C130077H22
product: unclassifiable, full insert
sequence
5830405N20Rik 5830405N20Rik RIKEN cDNA 5830405N20 gene 49 2.5 BB202848
5830405N20Rik 5830405N20Rik RIKEN cDNA 5830405N20 gene 19 5.9 AK017900
9630005B12Rik 5830411O09Rik RIKEN cDNA 9630005B12 gene 139 2.4 BB431654
9630005B12Rik 5830411O09Rik RIKEN cDNA 9630005B12 gene 114 2.7 BB431654
5830426I05Rik 5830426I05Rik RIKEN cDNA 5830426I05 gene 102 6.9 NM_133762
AI595338 5830443L24Rik expressed sequence AI595338 174 75.0 NM_029509
5830458K16Rik 5830458K16Rik RIKEN cDNA 5830458K16 gene 23 4.8 BC024872
5830458K16Rik 5830458K16Rik RIKEN cDNA 5830458K16 gene 525 9.1 BC024872
5830482F20Rik 5830482F20Rik RIKEN cDNA 5830482F20 gene 122 3.6 AW493583
5830484A20Rik 5830484A20Rik RIKEN cDNA 5830484A20 gene 99 4.8 AW909306
— 6030405P05Rik Mus musculus 13 days embryo male 125 7.5 BM244999
testis cDNA, RIKEN full-length enriched
library, clone: 6030405P05
product: unclassifiable, full insert
sequence
6030423D04Rik 6030423D04Rik RIKEN cDNA 6030423D04 gene 48 6.1 BE986588
6230416J20Rik 6230416J20Rik RIKEN cDNA 6230416J20 gene 37 2.2 BB794620
6330406L22Rik 6330406L22Rik RIKEN cDNA 6330406L22 gene 56 7.7 AK018130
6330407A03Rik 6330407A03Rik RIKEN cDNA 6330407A03 gene 60 3.3 AW519657
6330412F12Rik 6330412F12Rik RIKEN cDNA 6330412F12 gene 303 2.0 BG066220
6330442E10Rik 6330442E10Rik RIKEN cDNA 6330442E10 gene 22 7.5 AV328515
— 6330442E10Rik — 82 4.2 BB302103
6330500D04Rik 6330500D04Rik RIKEN cDNA 6330500D04 gene 87 2.8 BB867666
6330500D04Rik 6330500D04Rik RIKEN cDNA 6330500D04 gene 104 3.9 BM242294
6330500D04Rik 6330500D04Rik RIKEN cDNA 6330500D04 gene 66 2.3 AV329070
6330503K22Rik 6330503K22Rik RIKEN cDNA 6330503K22 gene 182 2.3 BG070835
6330583I20Rik 6330583I20Rik RIKEN cDNA 6330583I20 gene 43 2.5 BM248637
— 6430570G24 Mus musculus adult male olfactory brain 241 3.1 BG069663
cDNA, RIKEN full-length enriched library,
clone: 6430570G24 product: unknown
EST, full insert sequence
— 6430570G24 Mus musculus adult male olfactory brain 606 3.8 BG069663
cDNA, RIKEN full-length enriched library,
clone: 6430570G24 product: unknown
EST, full insert sequence
MGC66590 6430706D22Rik Unknown (protein for MGC: 66590) 24 2.3 BC004768
MGC66590 6430706D22Rik Unknown (protein for MGC: 66590) 271 2.3 BM248225
6530401D17Rik 6530401D17Rik RIKEN cDNA 6530401D17 gene 34 2.7 AK013740
6820428D13 6820428D13 hypothetical protein 6820428D13 39 2.7 BG064903
— 8030448K23Rik Mus musculus transcribed sequences 98 2.1 BM204579
8430437G11Rik 8430437G11Rik RIKEN cDNA 8430437G11 gene 271 2.2 BC007160
9030408N13Rik 9030408N13Rik RIKEN cDNA 9030408N13 gene 66 7.0 NM_025779
9030625A04Rik 9030625A04Rik RIKEN cDNA 9030625A04 gene 217 2.0 AV373606
9130002C22Rik 9130002C22Rik RIKEN cDNA 9130002C22 gene 476 24.4 BM243571
9130017N09Rik 9130017N09Rik RIKEN cDNA 9130017N09 gene 339 2.5 BQ030875
9130019I15Rik 9130019I15Rik RIKEN cDNA 9130019I15 gene 16 46.3 AK018636
9130022K13Rik 9130022K13Rik RIKEN cDNA 9130022K13 gene 65 5.6 AK018646
— 9130211I03Rik Mus musculus similar to Jun dimerization 64 4.9 AK020278
protein 1 gene (LOC381319), mRNA
9130422G05Rik 9130422G05Rik RIKEN cDNA 9130422G05 gene 177 5.0 AK018685
9130422G05Rik 9130422G05Rik RIKEN cDNA 9130422G05 gene 195 4.4 AK018685
9230105E10Rik 9230105E10Rik RIKEN cDNA 9230105E10 gene 108 3.6 BB433710
— 9230110J10 Mus musculus transcribed sequences 58 4.4 BG967674
9230117N10Rik 9230117N10Rik RIKEN cDNA 9230117N10 gene 222 7.6 NM_133775
9330132E09Rik 9330132E09Rik RIKEN cDNA 9330132E09 gene 189 2.3 AV336691
9330175E14Rik 9330175E14Rik RIKEN cDNA 9330175E14 gene 11 8.0 BB082472
MGC6357 9430034N14Rik hypothetical protein MGC6357 68 2.2 BB667558
— 9430065F17Rik Mus musculus 12 days embryo 30 2.1 AK021377
embryonic body between diaphragm
region and neck cDNA, RIKEN full-length
enriched library, clone: 9430065F17
product: unclassifiable, full insert
sequence
9430077D24Rik 9430077D24Rik RIKEN cDNA 9430077D24 gene 559 2.0 BG865652
— 9530028C05 Mus musculus adult male testis cDNA, 278 3.9 BQ175154
RIKEN full-length enriched library,
clone: 4921508F21 product: similar to
HISTOCOMPATIBILITY 2, CLASS II
ANTIGEN E BETA [Mus musculus], full
insert sequence
— 9530028C05 Mus musculus adult male testis cDNA, 228 4.6 BQ175154
RIKEN full-length enriched library,
clone: 4921508F21 product: similar to
HISTOCOMPATIBILITY 2, CLASS II
ANTIGEN E BETA [Mus musculus], full
insert sequence
— 9530053H05Rik — 108 4.5 AK020608
9630044O09Rik 9630044O09Rik RIKEN cDNA 9630044O09 gene 71 3.0 BB704967
AI645720 9630054F20Rik expressed sequence AI645720 106 2.1 BB131620
— 9630055N22Rik Mus musculus adult retina cDNA, RIKEN 523 1.9 BB276950
full-length enriched library,
clone: A930001C09 product: TAIL
FIBROBLAST RECEPTOR FOR FELINE
LEUKEMIA VIRUS SUBGROUP C
homolog [Mus dunni], full insert sequence
9830147J24Rik 9830147J24Rik RIKEN cDNA 9830147J24 gene 83 38.2 BC010229
— A130052D22 Mus musculus transcribed sequence with 448 2.1 BB194075
strong similarity to protein
ref: NP_057365.1 (H. sapiens) STE20-like
kinase; STE2-like kinase [Homo sapiens]
A130092J06Rik A130092J06Rik RIKEN cDNA A130092J06 gene 141 3.6 BI111848
A130096K20 A130096K20 hypothetical protein A130096K20 576 2.5 AV256780
— A230061C15Rik Mus musculus adult male hypothalamus 112 3.2 BB153043
cDNA, RIKEN full-length enriched library,
clone: A230061C15 product: unknown
EST, full insert sequence
A330021E22Rik A330021E22Rik RIKEN cDNA A330021E22 gene 52 2.2 BB561281
A330042H22 A330042H22 hypothetical protein A330042H22 87 11.3 AW743924
— A330042I21Rik Mus musculus adult male spinal cord 1523 3.6 AI645293
cDNA, RIKEN full-length enriched library,
clone: A330042I21 product: unknown EST,
full insert sequence
A330102K04 A330102K04Rik hypothetical protein A330102K04 35 5.5 AA214835
— A430093F15Rik Mus musculus 0 day neonate thymus 54 4.9 BB209605
cDNA, RIKEN full-length enriched library,
clone: A430093F15 product: hypothetical
protein, full insert sequence
A430106J12Rik A430106J12Rik RIKEN cDNA A430106J12 gene 140 2.1 BB498608
A430107D22Rik A430107D22Rik RIKEN cDNA A430107D22 gene 68 4.8 AI481597
A430107D22Rik A430107D22Rik RIKEN cDNA A430107D22 gene 26 16.4 AV312663
— A530052I06Rik Mus musculus adult male aorta and vein 14 3.3 BM239855
cDNA, RIKEN full-length enriched library,
clone: A530052I06 product: unknown EST,
full insert sequence
A630077B13Rik A630077B13Rik RIKEN cDNA A630077B13 gene 5 183.1 BB239429
Znfn1a2 A730095J18Rik zinc finger protein, subfamily 1A, 2 59 3.6 BB291816
(Helios)
Znfn1a2 A730095J18Rik zinc finger protein, subfamily 1A, 2 273 2.4 BB319935
(Helios)
— AA536717 Mus musculus 3 days neonate thymus 31 3.2 BB201845
cDNA, RIKEN full-length enriched library,
clone: A630021I17 product: unknown EST,
full insert sequence
AA536743 AA536743 expressed sequence AA536743 368 2.6 BI248354
AA536743 AA536743 expressed sequence AA536743 543 3.0 BI248354
AA589481 AA589481 expressed sequence AA589481 123 2.1 BB826899
— AB124611 Mus musculus 13 days embryo male 65 10.6 BM246462
testis cDNA, RIKEN full-length enriched
library, clone: 6030438F01
product: unclassifiable, full insert
sequence
Abp1 Abp1 amiloride binding protein 1 (amine 188 8.7 BC021880
oxidase, copper-containing)
Facl4 Acsl4 fatty acid-Coenzyme A ligase, long chain 4 174 2.2 AB033886
Facl5 Acsl5; ACS2; fatty acid Coenzyme A ligase, long chain 5 2295 2.1 AK006541
ACS5; Facl5;
1700030F05Rik
Strm Actn1 striamin 153 2.0 BC003232
Actr3 Actr3 ARP3 actin-related protein 3 homolog 4339 2.2 BE372352
(yeast)
Actr3 Actr3 ARP3 actin-related protein 3 homolog 3734 2.2 BE372352
(yeast)
Adam12 Adam12 a disintegrin and metalloproteinase 141 2.4 NM_007400
domain 12 (meltrin alpha)
Adam8 Adam8 a disintegrin and metalloprotease domain 8 54 4.4 NM_007403
Adamts1 Adamts1 a disintegrin-like and metalloprotease 863 4.5 D67076
(reprolysin type) with thrombospondin
type 1 motif, 1
Adamts2 Adamts2 a disintegrin-like and metalloprotease 139 2.3 BM125019
(reprolysin type) with thrombospondin
type 1 motif, 2
Adamts4 Adamts4 a disintegrin-like and metalloprotease 60 5.6 BB443585
(reprolysin type) with thrombospondin
type 1 motif, 4
Adamts6 Adamts6 a disintegrin-like and metalloprotease 22 3.0 BB227648
(reprolysin type) with thrombospondin
type 1 motif, 6
— Adar Mus musculus transcribed sequence with 103 3.5 BB308291
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
Adcy7 Adcy7 adenylate cyclase 7 118 17.3 BB746807
Adfp Adfp adipose differentiation related protein 1090 2.7 NM_007408
Adrbk1 Adrbk1 adrenergic receptor kinase, beta 1 490 2.1 AF333028
4833444A01Rik Adrbk2 RIKEN cDNA 4833444A01 gene 235 2.0 BG073639
Agpat4 Agpat4 1-acylglycerol-3-phosphate O- 241 2.5 BE994529
acyltransferase 1 (lysophosphatidic acid
acyltransferase, delta)
AI114950 AI114950 expressed sequence AI114950 244 2.7 BB224153
— AI132321 Mus musculus transcribed sequence with 44 27.8 BB210623
weak similarity to protein
ref: NP_036400.1 (H. sapiens) similar to
vaccinia virus HindIII K4L ORF [Homo
sapiens]
AI854251 AI413582 expressed sequence AI854251 116 2.4 AV039444
— AI426953 Mus musculus 2 days neonate thymus 38 2.4 BE632903
thymic cells cDNA, RIKEN full-length
enriched library, clone: E430023L24
product: unknown EST, full insert
sequence
— AI447881 Mus musculus transcribed sequences 102 2.7 AI447881
AI447904 AI447904 expressed sequence AI447904 59 26.2 BM241008
AI447904 AI447904 expressed sequence AI447904 7 70.3 BM241008
— AI449310 Mus musculus transcribed sequences 72 2.4 AW552116
AI449441 AI449441 expressed sequence AI449441 91 2.5 AV094878
— AI451557 Mus musculus transcribed sequences 87 24.1 AV277444
AI452102 AI452102 expressed sequence AI452102 45 3.3 BB312740
AI467606 AI467606 expressed sequence AI467606 168 10.2 BB234337
AI467606 AI467606 expressed sequence AI467606 25 9.5 BB234337
— AI504062 Mus musculus 9 days embryo whole 415 2.7 BM238926
body cDNA, RIKEN full-length enriched
library, clone: D030050E20
product: unclassifiable, full insert
sequence
AI504432 AI504432 expressed sequence AI504432 30 15.1 BB202185
Kcna3 AI504432 potassium voltage-gated channel, 23 18.8 AI323624
shaker-related subfamily, member 3
AI597013 AI597013 expressed sequence AI597013 47 6.1 BB014626
AI597013 AI597013 expressed sequence AI597013 77 7.9 BB014626
LOC226691 AI607873 interferon-activatable protein 15 28.9 AI607873
AI661017 AI661017 expressed sequence AI661017 21 15.4 AV173260
— AI661384 Mus musculus transcribed sequences 11 14.9 BB034038
— AI848100 Mus musculus transcribed sequences 128 2.2 BB538816
Aif1 Aif1 allograft inflammatory factor 1 71 36.5 NM_019467
Aim1 Aim1 absent in melanoma 1 294 2.8 BM233292
Akr1c20 Akr1c20 aldo-keto reductase family 1, member 28 8.0 BC021607
C20
Akt3 Akt3 thymoma viral proto-oncogene 3 60 3.2 AF124142
Akt3 Akt3 thymoma viral proto-oncogene 3 47 4.1 AF124142
Sdccag8 Akt3 serologically defined colon cancer 171 3.6 BB521695
antigen 8
AL024069 AL024069 expressed sequence AL024069 314 2.8 AI504908
Aldh1a2 Aldh1a2 aldehyde dehydrogenase family 1, 303 5.9 NM_009022
subfamily A2
Aldh1b1 Aldh1b1 aldehyde dehydrogenase 1 family, 115 2.7 BC020001
member B1
Alox5ap Alox5ap arachidonate 5-lipoxygenase activating 181 13.7 BC026209
protein
Ankrd1 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 44 5.7 AK009959
2900037I21Rik Anln RIKEN cDNA 2900037I21 gene 62 7.4 BI690018
Anp32b Anp32b acidic nuclear phosphoprotein 32 family, 1716 2.1 NM_130889
member B
Anxa1 Anxa1 annexin A1 878 2.9 NM_010730
Anxa2 Anxa2 annexin A2 2454 2.9 NM_007585
Ap1s2 Ap1s2 adaptor-related protein complex 1, sigma 188 2.0 BE655707
2 subunit
Ap1s2 Ap1s2; EST1; adaptor-related protein complex 1, sigma 151 6.4 AK005223
1500012A13Rik 2 subunit
Apaf1 Apaf1 apoptotic protease activating factor 1 274 2.1 AK018076
Apob48r Apob48r apolipoprotein B48 receptor 95 3.6 NM_138310
Apobec1 Apobec1 apolipoprotein B editing complex 1 235 3.2 BC003792
App App amyloid beta (A4) precursor protein 26 2.3 AV348729
Arf3 Arf3 ADP-ribosylation factor 3 107 2.4 BQ175059
Arf6 Arf6 ADP-ribosylation factor 6 3548 2.1 BI248938
Arg2 Arg2 arginase type II 85 4.3 AV002218
Arg2 Arg2 arginase type II 145 4.3 NM_009705
6530401L14Rik Arhgap11a RIKEN cDNA 6530401L14 gene 62 8.0 AV349116
— Arhgap15 Mus musculus 16 days neonate thymus 38 5.4 BB234837
cDNA, RIKEN full-length enriched library,
clone: A130024J05 product: hypothetical
protein, full insert sequence
— Arhgap15 Mus musculus 16 days neonate thymus 58 3.1 BB234837
cDNA, RIKEN full-length enriched library,
clone: A130024J05 product: hypothetical
protein, full insert sequence
4933411B03Rik Arhgap19 RIKEN cDNA 4933411B03 gene 35 4.1 BG072763
A130039I20Rik Arhgap25 RIKEN cDNA A130039I20 gene 84 3.7 BM241218
Arhgap4 Arhgap4 Rho GTPase activating protein 4 117 2.6 NM_138630
AU043488 Arhgap9 expressed sequence AU043488 84 8.7 BB327418
Gli Arhgap9 GLI-Kruppel family member GLI 24 11.5 AU043488
Gli Arhgap9 GLI-Kruppel family member GLI 12 14.6 AU043488
Arhgdib Arhgdib Rho, GDP dissociation inhibitor (GDI) 1160 7.7 AK002516
beta
Arhgef6 Arhgef6 Rac/Cdc42 guanine nucleotide exchange 142 4.5 BM246754
factor (GEF) 6
D430024K22Rik Arid5a RIKEN cDNA D430024K22 gene 56 8.3 BC027152
Desrt Arid5b developmentally and sexually retarded 19 2.7 BB257077
with transient immune abnormalities
A630084M22Rik Arl7 RIKEN cDNA A630084M22 gene 254 2.8 BQ176306
1200015K23Rik Armc8 RIKEN cDNA 1200015K23 gene 115 2.2 BE995635
Arrb2 Arrb2 arrestin, beta 2 240 3.5 BC016642
Arts1 Arts1 type 1 tumor necrosis factor receptor 444 4.8 NM_030711
shedding aminopeptidase regulator
Arts1 Arts1 type 1 tumor necrosis factor receptor 221 4.1 AV287655
shedding aminopeptidase regulator
Asf1b Asf1b ASF1 anti-silencing function 1 homolog B 111 5.0 BC003428
(S. cerevisiae)
Asns Asns asparagine synthetase 329 2.3 BC005552
Asns Asns asparagine synthetase 103 4.0 AV212753
2610509G12Rik Atad2 RIKEN cDNA 2610509G12 gene 127 6.0 BM206009
Atf3 Atf3 activating transcription factor 3 109 6.6 BC019946
Atp10a Atp10a ATPase, class V, type 10A 37 5.7 BB487289
Atp10a Atp10a ATPase, class V, type 10A 26 3.5 BM249532
Atp8b2 Atp8b2 Atpase, class I, type 8B, member 2 248 2.6 BQ178970
— Atr Mus musculus 16 days neonate thymus 33 2.3 BM197239
cDNA, RIKEN full-length enriched library,
clone: A130049K15
product: unclassifiable, full insert
sequence
— AU020206 Mus musculus 3 days neonate thymus 172 10.7 BI151331
cDNA, RIKEN full-length enriched library,
clone: A630040D01 product: unknown
EST, full insert sequence
Aurkb Aurkb aurora kinase B 21 9.6 BC003261
Aurkb Aurkb aurora kinase B 30 11.7 BC003261
— AW049306 Mus musculus transcribed sequences 20 3.9 BE457612
— AW112010 Mus musculus transcribed sequences 438 32.5 BE688358
— AW121567 Mus musculus 12 days embryo spinal 33 2.9 BB461295
ganglion cDNA, RIKEN full-length
enriched library, clone: D130071A17
product: unknown EST, full insert
sequence
AW212607 AW212607 expressed sequence AW212607 64 3.1 AV325152
AW212607 AW212607 expressed sequence AW212607 74 5.9 BB308532
1810048P08Rik AW490415 RIKEN cDNA 1810048P08 gene 49 3.2 AK010874
— AW492955 Mus musculus transcribed sequences 182 2.1 AW492955
— AW547186 Mus musculus 13 days embryo male 47 3.4 BB044338
testis cDNA, RIKEN full-length enriched
library, clone: 6030487A22
product: unclassifiable, full insert
sequence
Srr AW550801 serine racemase 191 2.3 BM213835
Axud1 Axud1 AXIN1 up-regulated 1 100 4.5 BG070296
IkappaBNS AY078069 NF-kappa B inhibitor 26 9.0 AW495632
B230217C12Rik B230217C12Rik RIKEN cDNA B230217C12 gene 24 6.2 BB376573
Cugbp2 B230218O03 CUG triplet repeat, RNA binding protein 2 91 8.2 BB644164
Cugbp2 B230218O03 CUG triplet repeat, RNA binding protein 2 161 7.9 BB644164
B230315M08Rik B230315M08Rik RIKEN cDNA B230315M08 gene 113 2.8 AI536469
B2m B2m beta-2 microglobulin 71 11.6 AA170322
B2m B2m beta-2 microglobulin 9650 2.7 AI099111
B3gnt5 B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N- 40 3.7 BM214359
acetylglucosaminyltransferase 5
Bak1 Bak1 BCL2-antagonist/killer 1 113 2.1 AF402617
Bak1 Bak1 BCL2-antagonist/killer 1 93 5.6 NM_007523
A530094C12Rik Bank1 RIKEN cDNA A530094C12 gene 74 2.0 AI451642
— Basp1 Mus musculus 10 days neonate medulla 143 9.4 AK011545
oblongata cDNA, RIKEN full-length
enriched library, clone: B830039F09
product: BRAIN ACID SOLUBLE
PROTEIN 1 (BASP1 PROTEIN)
(NEURONAL AXONAL MEMBRANE
PROTEIN NAP-22) homolog [Rattus
norvegicus], full insert sequence
BB146404 BB146404 expressed sequence BB146404 17 4.5 BC025893
— BB220380 Mus musculus adult male bone cDNA, 33 3.7 AV281292
RIKEN full-length enriched library,
clone: 9830142N16
product: unclassifiable, full insert
sequence
BC003236 BC003236 cDNA sequence BC003236 999 2.4 BB231897
BC004701 BC004701 cDNA sequence BC004701 41 5.9 BC004701
BC006779 BC006779 cDNA sequence BC006779 296 3.8 BE853170
BC010462 BC010462 cDNA sequence BC010462 208 3.5 BC010462
A530020G20Rik BC010552 RIKEN cDNA A530020G20 gene 21 3.3 AV256906
BC010552 BC010552 cDNA sequence BC010552 133 3.6 BC025548
BC013672 BC013672 cDNA sequence BC013672 9 8.7 BC013672
BC013712 BC013712 cDNA sequence BC013712 130 12.3 BB262491
BC023105 BC023105 cDNA sequence BC023105 46 70.3 BC023105
BC023179 BC023179 cDNA sequence BC023179 39 2.0 BC023179
BC023741 BC023741 cDNA sequence BC023741 208 11.7 BB705351
BC023882 BC023882 cDNA sequence BC023882 238 2.8 BC027393
BC027057 BC027057 cDNA sequence BC027057 80 3.1 BE133443
BC027057 BC027057 cDNA sequence BC027057 33 8.4 BB040051
L259 BC028528 L259 146 4.1 BC028528
BC031748 BC031748 cDNA sequence BC031748 46 2.5 BB709811
— BC031781 — 246 2.0 AV312901
BC032204 BC032204 cDNA sequence BC032204 91 9.3 BG066664
— BC033596 Mus musculus 16 days neonate thymus 56 2.6 BB162048
cDNA, RIKEN full-length enriched library,
clone: A130086M19 product: unknown
EST, full insert sequence
BC037703 BC037703 cDNA sequence BC037703 87 2.5 AV231983
9830126M18 BC052328 hypothetical protein 9830126M18 113 6.4 BM224662
B930060C03 BC065123 hypothetical protein B930060C03 354 3.9 BM239162
Baz1a BC065123 bromodomain adjacent to zinc finger 340 2.5 AV357135
domain 1A
4732427B05 BC066140 hypothetical protein 4732427B05 68 2.3 AV114409
— BC067047 Mus musculus adult male testis cDNA, 142 3.6 BB794978
RIKEN full-length enriched library,
clone: 4930413J11 product: mitochondria
located 1 homolog (human), full insert
sequence
— BC068171 Mus musculus similar to DYSKERIN 501 2.2 BG068512
(LOC245474), mRNA
Bcl11b Bcl11b B-cell leukemia/lymphoma 11B 160 2.2 BM117007
Bcl2l11 Bcl2l11 BCL2-like 11 (apoptosis facilitator) 62 2.6 BB667581
Bcl2l11 Bcl2l11 BCL2-like 11 (apoptosis facilitator) 114 3.4 BM120925
Bcl2l11 Bcl2l11 BCL2-like 11 (apoptosis facilitator) 481 2.5 BM120925
Bcl2l11 Bcl2l11 BCL2-like 11 (apoptosis facilitator) 401 3.9 BB667581
Bcl3 Bcl3 B-cell leukemia/lymphoma 3 203 3.8 NM_033601
Bcor Bcor Bcl6 interacting corepressor 181 2.2 AK018370
Bgn Bgn biglycan 2040 3.2 AI931862
Bgn Bgn biglycan 2268 2.8 BC019502
Birc1b Birc1b baculoviral IAP repeat-containing 1b 148 2.3 NM_010872
Birc1e Birc1e baculoviral IAP repeat-containing 1e 59 2.2 NM_010870
Birc1f Birc1f baculoviral IAP repeat-containing 1f 79 2.5 AI451585
Birc3 Birc2 baculoviral IAP repeat-containing 3 824 2.3 NM_007465
Birc2 Birc3 baculoviral IAP repeat-containing 2 628 5.7 NM_007464
Birc5 Birc5 baculoviral IAP repeat-containing 5 58 18.6 BC004702
Bnip2 Bnip2 BCL2/adenovirus E1B 19 kDa-interacting 724 2.4 AV144704
protein 1, NIP2
Bnip2 Bnip2; Nip21; BCL2/adenovirus E1B 19 kDa-interacting 667 2.2 AK014659
BNIP2beta; protein 1, NIP2
5730523P12Rik
2310015I10Rik Brd4 RIKEN cDNA 2310015I10 gene 269 13.8 BC008532
A730011O11Rik Brrn1 RIKEN cDNA A730011O11 gene 204 4.6 BB725358
A730011O11Rik Brrn1 RIKEN cDNA A730011O11 gene 81 3.6 BC021499
Bspry Bspry B-box and SPRY domain containing 552 3.3 NM_138653
Bst1 Bst1 bone marrow stromal cell antigen 1 167 4.5 AI647987
Btg1 Btg1 B-cell translocation gene 1, anti- 3872 2.3 L16846
proliferative
Btk Btk Bruton agammaglobulinemia tyrosine 26 8.8 NM_013482
kinase
Btla Btla B and T lymphocyte associated 91 7.9 BM240873
Bub1b Bub1b budding uninhibited by benzimidazoles 1 6 12.3 AU045529
homolog, beta (S. cerevisiae)
Bub3 Bub3 budding uninhibited by benzimidazoles 3 20 3.6 BB449877
homolog (S. cerevisiae)
Bzrp Bzrp benzodiazepine receptor, peripheral 1248 2.1 BB132602
— C030046G05 Mus musculus adult male corpus striatum 89 3.4 BE691546
cDNA, RIKEN full-length enriched library,
clone: C030046G05 product: unknown
EST, full insert sequence
C130032J12Rik C130032J12Rik RIKEN cDNA C130032J12 gene 202 2.0 BB192700
C130036J11 C130036J11 hypothetical protein C130036J11 8 8.1 BB072624
C1qa C1qa complement component 1, q 489 8.8 NM_007572
subcomponent, alpha polypeptide
C1qb C1qb complement component 1, q 147 34.3 BB111335
subcomponent, beta polypeptide
C1qb C1qb complement component 1, q 420 6.7 AW227993
subcomponent, beta polypeptide
C1qb C1qb complement component 1, q 363 14.1 NM_009777
subcomponent, beta polypeptide
C1qg C1qg complement component 1, q 185 20.8 NM_007574
subcomponent, gamma polypeptide
C1r C1r complement component 1, r 382 9.4 NM_023143
subcomponent
C1s C1s complement component 1, s 395 12.7 BC022123
subcomponent
C2 C2 complement component 2 (within H-2S) 1215 3.5 NM_013484
— C2 — 1241 4.6 AV290571
— C2 — 855 4.4 AV227574
C2ta C2ta class II transactivator 43 13.2 AF042158
C2ta C2ta class II transactivator 89 10.8 AF042158
C3 C3 complement component 3 437 29.7 K02782
C330012H03Rik C330012H03Rik RIKEN cDNA C330012H03 gene 69 2.8 BB098431
C330027C09Rik C330027C09Rik RIKEN cDNA C330027C09 gene 53 5.5 AU018569
C3ar1 C3ar1 complement component 3a receptor 1 113 3.5 NM_009779
C3ar1 C3ar1 complement component 3a receptor 1 38 10.2 BB333624
C3ar1 C3ar1 complement component 3a receptor 1 50 10.0 NM_009779
C4 C4 complement component 4 (within H-2S) 894 8.4 NM_009780
C5r1 C5r1; C5aR; complement component 5, receptor 1 41 3.4 NM_007577
Cd88
C630016B22Rik C630016B22Rik RIKEN cDNA C630016B22 gene 523 2.0 BB711990
C630016B22Rik C630016B22Rik RIKEN cDNA C630016B22 gene 786 2.3 BB771888
— C730049O14Rik Mus musculus adult male liver tumor 167 4.8 BB200607
cDNA, RIKEN full-length enriched library,
clone: C730049O14 product: unknown
EST, full insert sequence
C79407 C79407 expressed sequence C79407 51 3.3 BB540053
C79407 C79407 expressed sequence C79407 45 6.4 BE951628
— C79445 Mus musculus 18-day embryo whole 166 3.7 C79445
body cDNA, RIKEN full-length enriched
library, clone: 1100001P14
product: TUBULIN, BETA 5 homolog
[Homo sapiens], full insert sequence
C80638 C80638 expressed sequence C80638 38 3.5 AV251613
B130036O03 C86302 hypothetical protein B130036O03 256 2.6 BB295220
— C86813; FM2; — 45 3.0 C86813
lerepo1
— C86813; FM2; — 284 5.6 C86813
lerepo1
— Cacnb2 Mus musculus adult male hippocampus 7 2.8 AV154947
cDNA, RIKEN full-length enriched library,
clone: 2900072G11 product: unknown
EST, full insert sequence
Calm1 Calm1 calmodulin 1 2311 2.2 AU079514
Calmbp1 Calmbp1 calmodulin binding protein 1 21 4.2 BB648052
E030025C11Rik Camk1d RIKEN cDNA E030025C11 gene 47 4.7 BG071931
Camk2d Camk2d calcium/calmodulin-dependent protein 69 2.0 BB373572
kinase II, delta
Capg Capg capping protein (actin filament), gelsolin- 221 7.7 NM_007599
like
Capg Capg capping protein (actin filament), gelsolin- 77 2.1 BB136012
like
Cappa1 Capza1 capping protein alpha 1 2195 2.5 AV267494
— Capza1 — 2695 2.2 AI463215
Car13 Car13 carbonic anhydrase 13 132 2.3 AK010166
Card11 Card11 caspase recruitment domain family, 24 4.6 AV095659
member 11
Card4 Card4 caspase recruitment domain 4 228 3.2 BB138330
Casp1 Casp1 caspase 1 94 9.4 BC008152
Casp12 Casp12 caspase 12 122 3.6 NM_009808
Casp12 Casp12 caspase 12 145 6.8 NM_009808
Casp3 Casp3 caspase 3, apoptosis related cysteine 312 2.2 D86352
protease
Casp3 Casp3 caspase 3, apoptosis related cysteine 707 2.6 BG070529
protease
Casp4 Casp4 caspase 4, apoptosis-related cysteine 82 13.6 NM_007609
protease
Casp7 Casp7 caspase 7 234 3.7 U67321
Casp7 Casp7 caspase 7 528 2.8 NM_007611
Cbfb Cbfb core binding factor beta 1387 2.3 NM_022309
— Cblb Mus musculus transcribed sequences 134 3.5 BB205662
Cblb Cblb Casitas B-lineage lymphoma b 258 2.1 AW545867
Ccl11 Ccl11 small chemokine (C-C motif) ligand 11 21 4.7 NM_011330
Ccl12 Ccl12 chemokine (C-C motif) ligand 12 11 49.6 U50712
Ccl2 Ccl2 chemokine (C-C motif) ligand 2 43 28.9 AF065933
Ccl4 Ccl4 chemokine (C-C motif) ligand 4 95 4.5 AF128218
Ccl5 Ccl5 chemokine (C-C motif) ligand 5 34 140.5 NM_013653
Ccl6 Ccl6 chemokine (C-C motif) ligand 6 85 8.9 BC002073
Ccl7 Ccl7 chemokine (C-C motif) ligand 7 54 6.2 AF128193
Ccl8 Ccl8 chemokine (C-C motif) ligand 8 115 16.0 NM_021443
Ccl9 Ccl9 chemokine (C-C motif) ligand 9 25 15.6 AF128196
Ccl9 Ccl9 chemokine (C-C motif) ligand 9 70 9.8 AF128196
Ccnb1 Ccnb1 cyclin B1 102 7.1 NM_007629
Ccnb1 Ccnb1 cyclin B1 55 12.1 NM_007629
Ccnb1 Ccnb1 cyclin B1 14 22.1 AU015121
Ccnd2 Ccnd2 cyclin D2 420 2.3 BQ175880
— Ccne1 — 70 3.9 BB293079
Ccne2 Ccne2 cyclin E2 47 4.5 AF091432
Ccnf Ccnf cyclin F 11 9.5 NM_007634
Ccr1 Ccr1 chemokine (C-C motif) receptor 1 81 9.2 AV231648
Ccr2 Ccr2 chemokine (C-C) receptor 2 123 23.0 BB148128
Ccr2 Ccr2 chemokine (C-C) receptor 2 87 7.6 BB148128
Ccr2 Ccr2 chemokine (C-C) receptor 2 70 24.5 BB148128
Ccr5 Ccr5 chemokine (C-C motif) receptor 5 41 16.8 X94151
Ccr5 Ccr5 chemokine (C-C motif) receptor 5 31 7.6 X94151
Ccr5 Ccr5 chemokine (C-C motif) receptor 5 73 18.6 D83648
Ccr9 Ccr9 chemokine (C-C motif) receptor 9 30 4.6 AJ131357
Ccrl2 Ccrl2 chemokine (C-C motif) receptor-like 2 138 2.5 AJ318863
Cd14 Cd14 CD14 antigen 359 16.5 NM_009841
Cd160 Cd160 CD160 antigen 121 2.4 NM_018767
Cd160 Cd160 CD160 antigen 16 9.7 AU045688
Cd1d1 Cd1d1 CD1d1 antigen 67 4.1 NM_007639
Mox2 Cd200 antigen identified by monoclonal antibody 591 2.2 AF004023
MRC OX-2
F630003A18Rik Cd200r1 RIKEN cDNA F630003A18 gene 21 5.2 BB770873
Cd22 Cd22 CD22 antigen 97 2.0 AF102134
Cd244 Cd244 CD244 natural killer cell receptor 2B4 14 7.0 NM_018729
Cd28 Cd28 CD28 antigen 16 26.5 AV313615
Cd28 Cd28 CD28 antigen 43 22.1 NM_007642
Cd38 Cd38 CD38 antigen 191 2.7 NM_007646
Cd38 Cd38 CD38 antigen 455 3.7 BB256012
Cd3e Cd3e CD3 antigen, epsilon polypeptide 31 27.4 NM_007648
Cd44 Cd44 CD44 antigen 117 15.9 AW146109
Cd47 Cd47 CD47 antigen (Rh-related antigen, 1584 2.1 NM_010581
integrin-associated signal transducer)
Cd47 Cd47 CD47 antigen (Rh-related antigen, 2922 2.4 NM_010581
integrin-associated signal transducer)
Cd48 Cd48 CD48 antigen 82 20.7 BE634960
Cd5 Cd5 CD5 antigen 77 6.3 NM_007650
Cd52 Cd52 CD52 antigen 474 28.2 NM_013706
— Cd53 Mus musculus transcribed sequences 13 7.7 BM239715
Cd6 Cd6 CD6 antigen 18 11.9 U12434
Cd68 Cd68 CD68 antigen 189 7.9 BC021637
Cd69 Cd69 CD69 antigen 22 13.0 AK017979
Cd72 Cd72 CD72 antigen 51 10.7 BC003824
Cd79b Cd79b CD79B antigen 54 2.7 NM_008339
Cd83 Cd83 CD83 antigen 94 7.4 NM_009856
Cd84 Cd84 CD84 antigen 44 8.2 NM_013489
Cd86 Cd86 CD86 antigen 53 10.4 NM_019388
Cd86 Cd86 CD86 antigen 38 11.2 NM_019388
Cd8a Cd8a CD8 antigen, alpha chain 96 11.3 BB154331
Cd8a Cd8a CD8 antigen, alpha chain 71 18.2 M12825
Cd8a Cd8a CD8 antigen, alpha chain 60 31.2 M12825
1700109I12Rik Cd96 RIKEN cDNA 1700109I12 gene 99 2.9 NM_032465
Elovl1 Cdc20 elongation of very long chain fatty acids 307 5.7 BB041150
(FEN1/Elo2, SUR4/Elo3, yeast)-like 1
Cdc20 Cdc20 cell division cycle 20 homolog (S. cerevisiae) 302 3.1 NM_023223
Cdc25b Cdc25b cell division cycle 25 homolog B (S. cerevisiae) 110 2.8 NM_023117
Cdc2a Cdc2a cell division cycle 2 homolog A (S. pombe) 170 5.9 NM_007659
Cdc45l Cdc45l cell division cycle 45 homolog (S. cerevisiae)- 104 2.8 NM_009862
like
Cdc7 Cdc7 cell division cycle 7 (S. cerevisiae) 45 5.1 AB018574
2610311M19Rik Cdca2 RIKEN cDNA 2610311M19 gene 58 5.2 BG065056
2610311M19Rik Cdca2 RIKEN cDNA 2610311M19 gene 27 6.7 BG065056
Cdca3 Cdca3 cell division cycle associated 3 200 3.4 BI081061
Cdca4 Cdca4 cell division cycle associated 4 200 2.1 BB329505
Cdca4 Cdca4 cell division cycle associated 4 280 3.2 AF322238
D4Ertd421e Cdca8 DNA segment, Chr 4, ERATO Doi 421, 57 12.2 AV307110
expressed
D4Ertd421e Cdca8 DNA segment, Chr 4, ERATO Doi 421, 105 8.3 BB702047
expressed
D4Ertd421e Cdca8 DNA segment, Chr 4, ERATO Doi 421, 67 4.8 AV307110
expressed
Cdh11 Cdh11 cadherin 11 381 2.8 NM_009866
Cdk6 Cdk6 cyclin-dependent kinase 6 16 3.0 NM_009873
Cdkn1a Cdkn1a cyclin-dependent kinase inhibitor 1A 231 3.9 AK007630
(P21)
Cds1 Cds1 CDP-diacylglycerol synthase 1 324 2.0 BI152841
Cdyl Cdyl chromodomain protein, Y chromosome- 188 2.1 AF081260
like
Cebpb Cebpb CCAAT/enhancer binding protein 672 3.6 NM_009883
(C/EBP), beta
Cebpb Cebpb CCAAT/enhancer binding protein 214 2.9 AB012278
(C/EBP), beta
Cebpd Cebpd CCAAT/enhancer binding protein 236 5.5 BB831146
(C/EBP), delta
Cenpa Cenpa centromere autoantigen A 75 8.8 AV132173
BC049989 Cenpe cDNA sequence BC049989 13 2.3 BG068387
BC049989 Cenpe cDNA sequence BC049989 136 3.1 BG916502
Lek1 Cenpf leucine, glutamic acid, lysine family 1 89 3.4 BE848253
protein
Cenph Cenph centromere autoantigen H 22 5.1 BC025084
Centb1 Centb1 centaurin, beta 1 228 2.4 BB757196
Kctd11 Centb1 potassium channel tetramerisation 110 5.9 BB115902
domain containing 11
AA968343 Cep1 expressed sequence AA968343 166 2.2 BB466021
Cfi Cfi complement component factor i 364 3.3 NM_007686
Ch25h Ch25h cholesterol 25-hydroxylase 90 17.6 NM_009890
Chaf1b Chaf1b chromatin assembly factor 1, subunit B 81 3.3 BC013532
(p60)
Chek1 Chek1 checkpoint kinase 1 homolog (S. pombe) 29 4.7 NM_007691
Chi3l3 Chi3l3 chitinase 3-like 3 15 64.7 NM_009892
Chi3l4 Chi3l4 chitinase 3-like 4 76 13.4 AY065557
Chsy1 Chsy1 carbohydrate (chondroitin) synthase 1 640 2.0 BQ174991
Ckap2 Ckap2 cytoskeleton associated protein 2 121 2.8 BM208103
1700001C14Rik Cklf RIKEN cDNA 1700001C14 gene 169 2.1 AY047360
Cklfsf7 Cklfsf7 chemokine-like factor super family 7 48 3.2 BC026773
Cks1 Cks1b CDC28 protein kinase 1 181 4.6 NM_016904
Cks1 Cks1b CDC28 protein kinase 1 323 6.2 NM_016904
Clca2 Clca2 chloride channel calcium activated 2 39 3.1 AF108501
Cldn1 Cldn1 claudin 1 471 3.0 AV227581
Clecsf10 Clecsf10 C-type (calcium dependent, carbohydrate 68 6.8 NM_020001
recognition domain) lectin, superfamily
member 10
Clecsf10 Clecsf10 C-type (calcium dependent, carbohydrate 16 11.7 AF240358
recognition domain) lectin, superfamily
member 10
Clecsf12 Clecsf12 C-type (calcium dependent, carbohydrate 197 9.5 NM_020008
recognition domain) lectin, superfamily
member 12
Clecsf5 Clecsf5 C-type (calcium dependent, 56 10.9 NM_021364
carbohydrate-recognition domain) lectin,
superfamily member 5
1810046I24Rik Clecsf6 RIKEN cDNA 1810046I24 gene 29 7.2 BC006623
Clecsf6 Clecsf6 C-type (calcium dependent, carbohydrate 65 4.6 NM_011999
recognition domain) lectin, superfamily
member 6
Clecsf8 Clecsf8 C-type (calcium dependent, carbohydrate 25 4.5 NM_010819
recognition domain) lectin, superfamily
member 8
Clecsf9 Clecsf9 C-type (calcium dependent, carbohydrate 38 3.4 NM_019948
recognition domain) lectin, superfamily
member 9
Clecsf9 Clecsf9 C-type (calcium dependent, carbohydrate 17 30.6 NM_019948
recognition domain) lectin, superfamily
member 9
Clic1 Clic1 chloride intracellular channel 1 3468 2.6 NM_033444
E130314M08Rik Clspn RIKEN cDNA E130314M08 gene 40 7.0 BG067086
Cnn2 Cnn2 calponin 2 626 3.8 BI663014
4932442K20Rik Cnot6l RIKEN cDNA 4932442K20 gene 322 2.0 BC018506
Cnp1 Cnp1 cyclic nucleotide phosphodiesterase 1 113 2.5 M58045
Col15a1 Col15a1 procollagen, type XV 247 2.1 AF011450
Col1a2 Col1a2 procollagen, type I, alpha 2 1460 4.5 BF227507
Col1a2 Col1a2 procollagen, type I, alpha 2 392 8.6 BF227507
Col3a1 Col3a1 procollagen, type III, alpha 1 165 7.9 AW550625
Col3a1 Col3a1 procollagen, type III, alpha 1 1468 5.7 AW550625
Col5a1 Col5a1 procollagen, type V, alpha 1 242 3.6 AW744319
Col5a2 Col5a2 procollagen, type V, alpha 2 65 3.8 AV229424
Col5a2 Col5a2 procollagen, type V, alpha 2 150 6.7 AV229424
Col6a2 Col6a2 procollagen, type VI, alpha 2 363 3.4 BI455189
Col6a3 Col6a3 procollagen, type VI, alpha 3 657 2.6 AF064749
— Col8a1 Mus musculus 6 days neonate head 211 4.4 AV292255
cDNA, RIKEN full-length enriched library,
clone: 5430419M07 product: unknown
EST, full insert sequence
Colec12 Colec12 collectin sub-family member 12 134 2.4 NM_130449
Copeb Copeb core promoter element binding protein 198 4.4 AF072403
Copeb Copeb core promoter element binding protein 501 6.3 AV025472
Copeb Copeb core promoter element binding protein 298 5.5 NM_011803
Coro1a Coro1a coronin, actin binding protein 1A 26 3.9 BB740218
Coro1a Coro1a coronin, actin binding protein 1A 168 24.0 BB740218
5830400N10Rik Coro2a RIKEN cDNA 5830400N10 gene 69 4.1 AU042532
5830400N10Rik Coro2a RIKEN cDNA 5830400N10 gene 68 4.2 AI316747
Cp Cp ceruloplasmin 727 3.9 BB009037
Cpne2 Cpne2 copine II 100 1.9 BC023348
Crem Crem cAMP responsive element modulator 373 3.3 AI467599
Crem Crem cAMP responsive element modulator 221 3.3 AI467599
Crip1 Crip1 cysteine-rich protein 1 (intestinal) 1191 3.7 NM_007763
Crlf1 Crlf1 cytokine receptor-like factor 1 63 10.0 NM_018827
— Crlf3 Mus musculus transcribed sequences 110 2.8 BG094104
Crlf3 Crlf3 cytokine receptor-like factor 3 426 2.4 BB161253
Crtam Crtam cytotoxic and regulatory T cell molecule 54 5.0 NM_019465
Csf1 Csf1 colony stimulating factor 1 (macrophage) 138 2.9 BM233698
Csf1 Csf1 colony stimulating factor 1 (macrophage) 73 3.2 M21149
Csf1 Csf1 colony stimulating factor 1 (macrophage) 213 5.5 BM233698
Csf2rb1 Csf2rb1 colony stimulating factor 2 receptor, beta 7 11.5 NM_007780
1, low-affinity (granulocyte-macrophage)
Csf2rb1 Csf2rb1 colony stimulating factor 2 receptor, beta 68 14.7 BB769628
1, low-affinity (granulocyte-macrophage)
Csf2rb2 Csf2rb2 colony stimulating factor 2 receptor, beta 43 11.4 NM_007781
2, low-affinity (granulocyte-macrophage)
Csf3r Csf3r colony stimulating factor 3 receptor 26 12.4 NM_007782
(granulocyte)
Cspg2 Cspg2 chondroitin sulfate proteoglycan 2 42 7.2 NM_019389
Cspg2 Cspg2 chondroitin sulfate proteoglycan 2 59 8.2 BM251152
Cstb Cstb cystatin B 5561 2.3 NM_007793
Cstb Cstb cystatin B 2587 2.9 NM_007793
Cstf3 Cstf3 cleavage stimulation factor, 3′ pre-RNA, 51 2.5 BM218423
subunit 3
Tpbpb Ctla2a trophoblast specific protein beta 81 2.9 BG064656
Ctla4 Ctla4 cytotoxic T-lymphocyte-associated 26 21.0 NM_009843
protein 4
— Ctsc Mus musculus transcribed sequences 11 14.6 BG070233
Ctsc Ctsc cathepsin C 1593 8.7 NM_009982
— Ctsc Mus musculus transcribed sequences 32 5.3 AV367948
— Ctsc Mus musculus transcribed sequences 98 6.5 BM237633
Ctss Ctss cathepsin S 838 16.7 NM_021281
Cx3cl1 Cx3cl1 chemokine (C—X3—C motif) ligand 1 705 2.4 AF010586
Cx3cr1 Cx3cr1 chemokine (C—X3—C) receptor 1 139 2.4 BC012653
Cxcl1 Cxcl1 chemokine (C—X—C motif) ligand 1 177 2.7 BB554288
Cxcl1 Cxcl1 chemokine (C—X—C motif) ligand 1 74 6.2 NM_008176
Cxcl10 Cxcl10 chemokine (C—X—C motif) ligand 10 162 81.6 NM_021274
Cxcl11 Cxcl11 chemokine (C—X—C motif) ligand 11 46 10.5 NM_019494
Cxcl11 Cxcl11 chemokine (C—X—C motif) ligand 11 144 99.2 NM_019494
Cxcl13 Cxcl13 chemokine (C—X—C motif) ligand 13 68 4.4 AF030636
Cxcl14 Cxcl14 chemokine (C—X—C motif) ligand 14 260 3.1 AF252873
Cxcl14 Cxcl14 chemokine (C—X—C motif) ligand 14 124 9.2 AF252873
Cxcl16 Cxcl16 chemokine (C—X—C motif) ligand 16 1027 2.9 BC019961
Cxcl16 Cxcl16 chemokine (C—X—C motif) ligand 16 1429 3.7 BC019961
Cxcl16 Cxcl16 chemokine (C—X—C motif) ligand 16 199 2.9 AI662455
Cxcl9 Cxcl9 chemokine (C—X—C motif) ligand 9 125 176.4 NM_008599
Cxcr3 Cxcr3 chemokine (C—X—C motif) receptor 3 137 10.2 NM_009910
Cxcr4 Cxcr4 chemokine (C—X—C motif) receptor 4 133 3.6 D87747
Cybb Cybb cytochrome b-245, beta polypeptide 283 21.3 AV373944
Cybb Cybb cytochrome b-245, beta polypeptide 153 14.2 NM_007807
Cybb Cybb cytochrome b-245, beta polypeptide 161 9.1 AV373944
Cyp1b1 Cyp1b1 cytochrome P450, family 1, subfamily b, 259 3.4 BI251808
polypeptide 1
Cyp4f18 Cyp4f18 cytochrome P450, family 4, subfamily f, 19 26.1 NM_024444
polypeptide 18
Cyp4v3 Cyp4v3 cytochrome P450, family 4, subfamily v, 300 3.1 NM_133969
polypeptide 3
Cyp4v3 Cyp4v3 cytochrome P450, family 4, subfamily v, 137 3.9 NM_133969
polypeptide 3
Cyr61 Cyr61 cysteine rich protein 61 384 2.5 BM202770
Cysltr1 Cysltr1 cysteinyl leukotriene receptor 1 13 4.8 BC027102
Cysltr1 Cysltr1 cysteinyl leukotriene receptor 1 12 4.9 BC027102
— D030064D06Rik Mus musculus 9 days embryo whole 92 2.3 AW987520
body cDNA, RIKEN full-length enriched
library, clone: D030064D06
product: unknown EST, full insert
sequence
D11Ertd461e D11Ertd461e DNA segment, Chr 11, ERATO Doi 461, 26 5.5 C87579
expressed
D11Ertd759e D11Ertd759e DNA segment, Chr 11, ERATO Doi 759, 922 4.9 AW556558
expressed
D11Lgp2e D11Lgp2e DNA segment, Chr 11, Lothar 27 6.1 NM_030150
Hennighausen 2, expressed
D11Lgp2e D11Lgp2e DNA segment, Chr 11, Lothar 55 10.0 AF316999
Hennighausen 2, expressed
D11Wsu99e D11Wsu99e DNA segment, Chr 11, Wayne State 232 2.6 AV225714
University 99, expressed
D12Ertd551e D12Ertd551e DNA segment, Chr 12, ERATO Doi 551, 660 2.1 BI102044
expressed
— D12Ertd551e Mus musculus adult male tongue cDNA, 20 5.5 BQ175646
RIKEN full-length enriched library,
clone: 2310058N22 product: unknown
EST, full insert sequence
D12Ertd647e D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, 953 5.8 AW554405
expressed
D12Ertd647e D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, 1414 4.1 BI655075
expressed
4930513H15Rik D14Ertd581e RIKEN cDNA 4930513H15 gene 49 2.1 AK017117
D16Ertd472e D16Ertd472e DNA segment, Chr 16, ERATO Doi 472, 105 4.2 AV381575
expressed
D17H6S56E-5 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5 381 5.9 NM_033075
D17H6S56E-5 D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5 195 9.2 NM_033075
D2Ertd750e D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, 43 7.9 AU019491
expressed
— D330027G24Rik Mus musculus 13 days embryo heart 48 4.3 BB449568
cDNA, RIKEN full-length enriched library,
clone: D330027G24
product: unclassifiable, full insert
sequence
Mecp2 D630021H01Rik methyl CpG binding protein 2 55 2.0 BB499491
D730019B10 D730019B10 hypothetical protein D730019B10 23 12.8 BB508669
Rpl30 D730044K07Rik ribosomal protein L30 13 2.0 BB283415
D7Bwg0421e D7Bwg0421e DNA segment, Chr 7, Brigham & 31 8.1 BB667693
Women's Genetics 0421 expressed
D7Bwg0421e D7Bwg0421e DNA segment, Chr 7, Brigham & 59 8.4 AV370380
Women's Genetics 0421 expressed
Atp8a1 D830007B15Rik ATPase, aminophospholipid transporter 124 2.7 BB303874
(APLT), class I, type 8A, member 1
Atp8a1 D830007B15Rik ATPase, aminophospholipid transporter 164 4.3 BB303874
(APLT), class I, type 8A, member 1
Atp8a1 D830007B15Rik ATPase, aminophospholipid transporter 184 5.6 AW610650
(APLT), class I, type 8A, member 1
Atp8a1 D830007B15Rik ATPase, aminophospholipid transporter 150 2.9 BQ176779
(APLT), class I, type 8A, member 1
Atp8a1 D830007B15Rik ATPase, aminophospholipid transporter 213 4.3 AW610650
(APLT), class I, type 8A, member 1
Dapp1 Dapp1 dual adaptor for phosphotyrosine and 3- 91 3.9 NM_011932
phosphoinositides 1
Dapp1 Dapp1 dual adaptor for phosphotyrosine and 3- 54 4.4 NM_011932
phosphoinositides 1
Dcamkl1 Dcamkl1 double cortin and calcium/calmodulin- 3 4.7 AW105916
dependent protein kinase-like 1
Dcamkl1 Dcamkl1 double cortin and calcium/calmodulin- 27 5.4 AW105916
dependent protein kinase-like 1
Dcamkl1 Dcamkl1 double cortin and calcium/calmodulin- 18 9.8 AW105916
dependent protein kinase-like 1
Dcamkl1 Dcamkl1 double cortin and calcium/calmodulin- 12 19.7 BB757120
dependent protein kinase-like 1
Dck Dck deoxycytidine kinase 54 5.3 BE630687
Dck Dck deoxycytidine kinase 103 12.6 BB030204
Dck Dck deoxycytidine kinase 105 5.1 NM_007832
Dcn Dcn decorin 2578 2.7 NM_007833
— Ddef1 Mus musculus transcribed sequences 29 3.6 BG064109
Ddx21 Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 293 2.1 BM246099
21
Ddx39 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 940 2.6 BC020134
39
Ddx39 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1433 2.3 AV214253
39
6430573D20Rik Ddx58 RIKEN cDNA 6430573D20 gene 505 3.9 BG063981
Def6 Def6 differentially expressed in FDCP 6 54 4.9 AK010356
5830484J08Rik Depdc1a RIKEN cDNA 5830484J08 gene 14 8.5 BC005799
— Diap1 Mus musculus 7 days embryo whole 124 2.1 BB408240
body cDNA, RIKEN full-length enriched
library, clone: C430005H19
product: unknown EST, full insert
sequence
Dkk3 Dkk3 dickkopf homolog 3 (Xenopus laevis) 354 2.5 AK004853
Dkk3 Dkk3 dickkopf homolog 3 (Xenopus laevis) 293 2.3 AK004853
Hurp Dlg7 hepatoma up-regulated protein 24 3.2 BB132734
Hurp Dlg7 hepatoma up-regulated protein 34 4.5 BM250919
E130315B21Rik Dna2l RIKEN cDNA E130315B21 gene 363 2.0 BB546985
5330419I01Rik Dnajc9 RIKEN cDNA 5330419I01 gene 626 2.1 BM942465
Dnase1l3 Dnase1l3 deoxyribonuclease 1-like 3 47 6.4 BC012671
Dnase1l3 Dnase1l3 deoxyribonuclease 1-like 3 12 8.8 BC012671
Npn1 Dnm3 neoplastic progression 1 86 2.5 BB542096
Dnmt1 Dnmt1 DNA methyltransferase (cytosine-5) 1 308 2.9 BB165431
— Dock10 Mus musculus transcribed sequences 49 2.3 BB211894
Dock10 Dock10 dedicator of cytokinesis 10 17 3.0 BB763030
Dock10 Dock10 dedicator of cytokinesis 10 145 8.8 BF715043
— Dock11 Mus musculus 11 days pregnant adult 106 11.1 AK017170
female ovary and uterus cDNA, RIKEN
full-length enriched library,
clone: 5033414A21 product: inferred:
human CLASP-4 {Homo sapiens}, full
insert sequence
Dok1 Dok1 downstream of tyrosine kinase 1 169 2.1 BC013066
Donson Donson downstream neighbor of SON 150 2.7 BQ174742
Dpt Dpt dermatopontin 246 2.4 NM_019759
Dpysl2 Dpysl2 dihydropyrimidinase-like 2 1968 2.0 BQ174209
— Dpysl3 Mus musculus transcribed sequence with 78 3.7 AV161550
strong similarity to protein sp: Q14195
(H. sapiens) DPY3_HUMAN
Dihydropyrimidinase related protein-3
(DRP-3) (Unc-33-like phosphoprotein)
(ULIP protein) (Collapsin response
mediator protein 4) (CRMP-4)
Dsg2 Dsg2 desmoglein 2 693 2.1 BG092030
— Dtx3l Mus musculus transcribed sequence with 460 9.1 AV327407
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
BC044798 Dtx4 cDNA sequence BC044798 589 2.5 AV017487
2610016C23Rik Dufd1 RIKEN cDNA 2610016C23 gene 53 3.7 AK016786
Dusp10 Dusp10 dual specificity phosphatase 10 41 4.8 NM_022019
Dusp2 Dusp2 dual specificity phosphatase 2 54 5.0 L11330
Dutp Dut deoxyuridine triphosphatase 289 2.7 AF091101
— E030018N11Rik Mus musculus 0 day neonate lung cDNA, 314 3.4 BB794845
RIKEN full-length enriched library,
clone: E030018N11 product: hypothetical
protein, full insert sequence
E030024M05Rik E030024M05Rik RIKEN cDNA E030024M05 gene 259 2.1 BC025220
— E130113K08Rik Mus musculus transcribed sequences 31 4.5 BB491630
E130201N16Rik E130201N16Rik RIKEN cDNA E130201N16 gene 285 4.4 AJ132433
E2f1 E2f1 E2F transcription factor 1 80 2.3 AK017841
E2f2 E2f2 E2F transcription factor 2 22 4.3 BB543028
E2f7 E2f7 E2F transcription factor 7 33 3.5 BG069355
E330016A19Rik E330016A19Rik RIKEN cDNA E330016A19 gene 40 5.4 BB073366
E430004N04Rik E430004N04Rik RIKEN cDNA E430004N04 gene 65 7.1 BE628523
E430004N04Rik E430004N04Rik RIKEN cDNA E430004N04 gene 21 3.4 BB201286
E430019B13Rik E430019B13Rik RIKEN cDNA E430019B13 gene 51 2.2 BE630983
Ebi2 Ebi2 Epstein-Barr virus induced gene 2 51 4.5 BM242490
Ebi3 Ebi3 Epstein-Barr virus induced gene 3 70 2.9 NM_015766
Edg5 Edg5 endothelial differentiation, sphingolipid G- 152 2.5 AK003144
protein-coupled receptor, 5
Edg6 Edg6 endothelial differentiation, G-protein- 87 3.1 AV081616
coupled receptor 6
Ednra Ednra endothelin receptor type A 18 4.0 BC008277
D4Wsu27e Efhd2 DNA segment, Chr 4, Wayne State 163 52.1 AA409309
University 27, expressed
Egr1 Egr1 early growth response 1 317 5.3 NM_007913
Egr2 Egr2 early growth response 2 3 19.6 X06746
Egr2 Egr2 early growth response 2 35 16.7 X06746
Egr3 Egr3 early growth response 3 27 10.5 AV346607
Eif1a Eif1a eukaryotic translation initiation factor 1A 923 2.3 BM200591
Eif1a Eif1a eukaryotic translation initiation factor 1A 1090 2.4 BM200591
1300018P11Rik Eif4e3 RIKEN cDNA 1300018P11 gene 370 4.7 BC027014
1300018P11Rik Eif4e3 RIKEN cDNA 1300018P11 gene 464 5.1 BC027014
Pctk2 Elk3 PCTAIRE-motif protein kinase 2 465 2.5 BM243464
Elk3 Elk3 ELK3, member of ETS oncogene family 425 2.0 BC005686
Elmo1 Elmo1 engulfment and cell motility 1, ced-12 36 3.4 NM_080288
homolog (C. elegans)
Elmo1 Elmo1 engulfment and cell motility 1, ced-12 79 3.7 BC024727
homolog (C. elegans)
Emb Emb embigin 402 2.3 BG064842
Emb Emb embigin 609 2.7 BG064842
Emilin1 Emilin1 elastin microfibril interface located protein 1 179 2.7 NM_133918
Emilin2 Emilin2 elastin microfibril interface located protein 2 92 3.8 BB811788
Emp1 Emp1 epithelial membrane protein 1 1072 2.0 U25633
Emp3 Emp3 epithelial membrane protein 3 299 5.4 BC001999
Emr1 Emr1 EGF-like module containing, mucin-like, 227 3.9 U66888
hormone receptor-like sequence 1
Emr4 Emr4 EGF-like module containing, mucin-like, 20 14.8 AF396935
hormone receptor-like sequence 4
Emr4 Emr4 EGF-like module containing, mucin-like, 27 10.3 AF396935
hormone receptor-like sequence 4
Enc1 Enc1 ectodermal-neural cortex 1 264 6.4 BM120053
Enc1 Enc1 ectodermal-neural cortex 1 175 4.0 BM120053
Enpp4 Enpp4 ectonucleotide 657 2.2 AV280361
pyrophosphatase/phosphodiesterase 4
Entpd1 Entpd1 ectonucleoside triphosphate 160 3.4 BI151440
diphosphohydrolase 1
Entpd1 Entpd1 ectonucleoside triphosphate 89 2.4 BI151440
diphosphohydrolase 1
Eomes Eomes eomesodermin homolog (Xenopus laevis) 69 2.1 BB128925
Epb4.1l2 Epb4.1l2 erythrocyte protein band 4.1-like 2 528 2.0 BE951907
Eppk1 Eppk1 epiplakin 1 74 2.1 BC026387
2310046K10Rik Epsti1 RIKEN cDNA 2310046K10 gene 63 13.4 AK017174
2310046K10Rik Epsti1 RIKEN cDNA 2310046K10 gene 106 14.2 BF020640
— Espl1 Mus musculus 10 days neonate skin 91 2.7 BM200578
cDNA, RIKEN full-length enriched library,
clone: 4732457F20 product: unknown
EST, full insert sequence
Ets1 Ets1 E26 avian leukemia oncogene 1, 5′ 82 2.6 BC010588
domain
Ets1 Ets1 E26 avian leukemia oncogene 1, 5′ 564 3.2 BB151715
domain
Ets1 Ets1 E26 avian leukemia oncogene 1, 5′ 556 5.1 BB151715
domain
Etv3 Etv3 ets variant gene 3 88 2.0 BM932547
— Etv6 Mus musculus transcribed sequence with 73 2.4 BB735884
strong similarity to protein sp: P00722 (E. coli)
BGAL_ECOLI Beta-galactosidase
(Lactase)
Evi2a Evi2a ecotropic viral integration site 2a 54 7.7 BB236216
Evi2a Evi2a ecotropic viral integration site 2a 19 35.2 AI122415
Evl Evl Ena-vasodilator stimulated 96 2.5 AW546029
phosphoprotein
Evl Evl Ena-vasodilator stimulated 205 4.7 AW553781
phosphoprotein
Evl Evl Ena-vasodilator stimulated 159 3.7 NM_007965
phosphoprotein
Exo1 Exo1 exonuclease 1 65 2.4 BE986864
Exo1 Exo1 exonuclease 1 46 2.0 BE986864
2310032N20Rik Exosc8 RIKEN cDNA 2310032N20 gene 433 3.7 AK009584
Ezh2 Ezh2 enhancer of zeste homolog 2 256 4.0 NM_007971
(Drosophila)
F10 F10 coagulation factor X 75 2.5 NM_007972
F13a F13a1 coagulation factor XIII, alpha subunit 64 4.5 NM_028784
F2r F2r coagulation factor II (thrombin) receptor 1067 3.0 BQ173958
F2r F2r coagulation factor II (thrombin) receptor 2532 2.3 AV024285
F3 F3 coagulation factor III 542 2.8 BC024886
F730004D16Rik F730004D16Rik RIKEN cDNA F730004D16 gene 100 5.4 BM230330
— F730047E07Rik Mus musculus hypothetical LOC269515 37 4.7 BG071041
(LOC269515), mRNA
Fabp5 Fabp5 fatty acid binding protein 5, epidermal 504 3.0 BC002008
Fabp5 Fabp5 fatty acid binding protein 5, epidermal 150 3.5 BC002008
Fabp7 Fabp7 fatty acid binding protein 7, brain 795 5.2 NM_021272
Tnfrsf6 Fas tumor necrosis factor receptor 120 6.0 NM_007987
superfamily, member 6
Fbn1 Fbn1 fibrillin 1 269 3.3 AF007248
Fbn1 Fbn1 fibrillin 1 494 3.0 NM_007993
Fbxo5 Fbxo5 F-box only protein 5 119 5.0 AK011820
Fbxo6b Fbxo6b F-box only protein 6b 455 3.0 NM_015797
1110064L07Rik Fbxw17 RIKEN cDNA 1110064L07 gene 339 4.8 AV016303
Fcer1g Fcer1g Fc receptor, IgE, high affinity I, gamma 225 21.7 NM_010185
polypeptide
Fcgr1 Fcgr1 Fc receptor, IgG, high affinity I 123 4.8 BB075261
Fcgr1 Fcgr1 Fc receptor, IgG, high affinity I 74 21.0 AF143181
Fcgr2b Fcgr3 Fc receptor, IgG, low affinity IIb 161 11.4 NM_010188
Fcrl3 Fcrl3 Fc receptor-like 3 114 20.5 BC027310
Fen1 Fen1 flap structure specific endonuclease 1 262 3.1 NM_007999
Fer1l3 Fer1l3 fer-1-like 3, myoferlin (C. elegans) 208 4.0 BI555209
Fes Fes feline sarcoma oncogene 105 3.0 BG867327
Fes Fes feline sarcoma oncogene 101 3.8 BG867327
Fga Fga fibrinogen, alpha polypeptide 605 6.1 BC005467
Fgd2 Fgd2 FYVE, RhoGEF and PH domain 109 2.2 NM_013710
containing 2
Fgd3 Fgd3 FYVE, RhoGEF and PH domain 66 2.7 AK018025
containing 3
1500031J01Rik Fgfr1op2 RIKEN cDNA 1500031J01 gene 82 2.2 AB041650
Fgl2 Fgl2 fibrinogen-like protein 2 56 46.7 BF136544
Fgl2 Fgl2 fibrinogen-like protein 2 114 28.1 BF136544
Fgr Fgr Gardner-Rasheed feline sarcoma viral 120 5.4 NM_010208
(Fgr) oncogene homolog
Fgr Fgr Gardner-Rasheed feline sarcoma viral 105 4.3 BB165085
(Fgr) oncogene homolog
— Fkbp10 — 84 2.3 AI325255
Fli1 Fli1 Friend leukemia integration 1 228 3.5 BB138212
Fli1 Fli1 Friend leukemia integration 1 75 5.1 NM_008026
1110008K06Rik Fln29 RIKEN cDNA 1110008K06 gene 464 4.0 AK003586
5430425K04Rik Fmnl2 RIKEN cDNA 5430425K04 gene 576 2.3 AK017338
Fnbp1 Fnbp1 formin binding protein 1 211 2.3 BM244005
Fos Fos FBJ osteosarcoma oncogene 119 9.1 AV026617
Fosl2 Fosl2 fos-like antigen 2 247 4.1 BM245170
Foxa1 Foxa1 forkhead box A1 46 2.3 NM_008259
Foxj1 Foxj1 forkhead box J1 53 2.1 L13204
Foxp1 Foxp1 forkhead box P1 120 2.2 BG962849
Fprl1 Fprl1 formyl peptide receptor-like 1 30 48.3 NM_008039
Frk Frk fyn-related kinase 193 2.2 BB787292
Fscn1 Fscn1 fascin homolog 1, actin bundling protein 820 3.1 NM_007984
(Strongylocentrotus) purpuratus)
Fshprh1 Fshprh1 FSH primary response 1 8 6.8 BB258991
Fstl1 Fstl1 follistatin-like 1 469 4.4 BI452727
Fstl1 Fstl1 follistatin-like 1 73 2.2 BB540658
Fstl1 Fstl1 follistatin-like 1 739 4.0 BI452727
Fthfsdc1 Fthfsdc1 formyltetrahydrofolate synthetase domain 145 3.2 AV095209
containing 1
Fus Fus fusion, derived from t(12; 16) malignant 1474 2.6 AF224264
liposarcoma (human)
Fut4 Fut4 fucosyltransferase 4 16 6.5 AV309809
Fxyd5 Fxyd5 FXYD domain-containing ion transport 491 7.4 NM_008761
regulator 5
Fyb Fyb FYN binding protein 73 3.8 BE853428
Fyb Fyb FYN binding protein 64 18.3 BM243379
Fyb Fyb FYN binding protein 70 19.2 BB157866
Fyn Fyn Fyn proto-oncogene 217 3.1 NM_008054
Fyn Fyn Fyn proto-oncogene 369 2.9 NM_008054
G430022H21Rik G430022H21Rik RIKEN cDNA G430022H21 gene 108 2.6 BM247306
G430041M01Rik G430041M01Rik RIKEN cDNA G430041M01 gene 602 2.1 BG069073
— G430041M01Rik Mus musculus adult male corpora 36 6.9 BM211445
quadrigemina cDNA, RIKEN full-length
enriched library, clone: B230214O09
product: unknown EST, full insert
sequence
Gab3 Gab3 growth factor receptor bound protein 2- 35 2.5 BB037935
associated protein 3
— Gadd45b — 152 2.5 AI323528
Galgt1 Galgt1 UDP-N-acetyl-alpha-D-galactosamine:(N- 99 8.2 U18975
acetylneuraminyl)-
galactosylglucosylceramide-beta-1,4-N-
acetylgalactosaminyltransferase
Galnt12 Galnt12 UDP-N-acetyl-alpha-D- 92 2.6 AV376137
galactosamine:polypeptide N-
acetylgalactosaminyltransferase 12
Galnt6 Galnt6 UDP-N-acetyl-alpha-D- 7 11.2 AV231866
galactosamine:polypeptide N-
acetylgalactosaminyltransferase 6
— Gas2l3 Mus musculus hypothetical LOC237436 59 3.3 BB770972
(LOC237436), mRNA
— Gas2l3 Mus musculus hypothetical LOC237436 52 3.7 BB770972
(LOC237436), mRNA
Gas5 Gas5 growth arrest specific 5 2282 2.0 NM_013525
Gas5 Gas5 growth arrest specific 5 288 3.0 BI650268
Gas5 Gas5 growth arrest specific 5 121 5.2 AW547050
Gas5 Gas5 growth arrest specific 5 220 4.3 BC004622
Gbp1 Gbp1 guanylate nucleotide binding protein 1 9 54.5 NM_010259
Gbp2 Gbp2 guanylate nucleotide binding protein 2 272 53.4 BE197524
Gbp2 Gbp2 guanylate nucleotide binding protein 2 321 100.2 NM_010260
Gbp3 Gbp4 guanylate nucleotide binding protein 3 184 42.9 NM_018734
Gch Gch1 GTP cyclohydrolase 1 54 3.3 NM_008102
Gcnt1 Gcnt1 glucosaminyl (N-acetyl) transferase 1, 26 6.9 AK017462
core 2
Gda Gda guanine deaminase 106 11.9 AW911807
Gda Gda guanine deaminase 33 5.4 NM_010266
Gda Gda guanine deaminase 81 12.1 AW911807
1110035O14Rik Gdap10 RIKEN cDNA 1110035O14 gene 329 4.0 NM_010268
Gfpt1 Gfpt1 glutamine fructose-6-phosphate 74 2.7 AF334736
transaminase 1
Ggta1 Ggta1 glycoprotein galactosyltransferase alpha 42 3.2 M26925
1, 3
Ggta1 Ggta1 glycoprotein galactosyltransferase alpha 232 3.3 AF297615
1, 3
Ian1 Gimap4 immune associated nucleotide 1 2439 3.0 BC005577
Ian1 Gimap4 immune associated nucleotide 1 1384 2.4 BC005577
Ian3 Gimap7 immune associated nucleotide 3 52 14.1 BC026200
Ian3 Gimap7 immune associated nucleotide 3 9 7.7 BB223831
— Gimap8 Mus musculus similar to hypothetical 716 3.2 BM243674
protein (LOC243374), mRNA
— Gimap8 — 22 7.8 BB236014
Glipr1 Glipr1 GLI pathogenesis-related 1 (glioma) 144 14.8 BC025083
Glipr2 Glipr2 GLI pathogenesis-related 2 36 12.8 BM208214
Glipr2 Glipr2 GLI pathogenesis-related 2 49 8.2 BM208214
— Gls Mus musculus transcribed sequences 190 2.7 BM239869
Gmfg Gmfg glia maturation factor, gamma 310 5.7 NM_022024
Gmfg Gmfg glia maturation factor, gamma 76 5.9 NM_022024
— Gna13 Mus musculus transcribed sequences 227 2.0 BI180797
Gna13 Gna13 guanine nucleotide binding protein, alpha 1712 2.7 BG073165
13
Gnb4 Gnb4 guanine nucleotide binding protein, beta 4 290 2.1 BI713933
Gnb4 Gnb4 guanine nucleotide binding protein, beta 4 204 3.4 BI713933
Gng10 Gng10 guanine nucleotide binding protein (G 619 2.4 NM_025277
protein), gamma 10
— Gng2 Mus musculus 15 days embryo male 224 2.3 AV021455
testis cDNA, RIKEN full-length enriched
library, clone: 8030491K24
product: unknown EST, full insert
sequence
Gng2 Gng2 guanine nucleotide binding protein (G 91 7.8 BB522409
protein), gamma 2 subunit
— Gng2 Mus musculus 15 days embryo male 111 2.6 AV021455
testis cDNA, RIKEN full-length enriched
library, clone: 8030491K24
product: unknown EST, full insert
sequence
Gp38 Gp38 glycoprotein 38 383 2.6 NM_010329
Gpm6b Gpm6b glycoprotein m6b 249 3.0 AF254879
Gpm6b Gpm6b glycoprotein m6b 232 4.4 AK016567
Gpr132 Gpr132 G protein-coupled receptor 132 47 3.8 BB208670
F730001G15Rik Gpr171 RIKEN cDNA F730001G15 gene 17 17.5 BB229616
Gpr18 Gpr18 G protein-coupled receptor 18 100 9.9 BG145550
Gpr35 Gpr35 G protein-coupled receptor 35 15 14.0 NM_022320
Gpr43 Gpr43 G protein-coupled receptor 43 17 2.6 AV370830
Gpr64 Gpr64 G protein-coupled receptor 64 79 2.2 AV242919
Gpcr25 Gpr65 G-protein coupled receptor 25 50 13.6 NM_008152
Gpr68 Gpr68 G protein-coupled receptor 68 24 10.0 BB538372
Gpr84 Gpr84 G protein-coupled receptor 84 18 17.9 NM_030720
Gprk6 Gprk6 G protein-coupled receptor kinase 6 556 2.5 BB461269
Gprk6 Gprk6 G protein-coupled receptor kinase 6 299 2.1 AF040748
1810036L03Rik Gsdmdc1 RIKEN cDNA 1810036L03 gene 133 6.5 AK007710
Gsg2 Gsg2 germ cell-specific gene 2 34 3.1 BE457839
Gzma Gzma granzyme A 68 14.1 NM_010370
Gzmk Gzmk granzyme K 24 14.1 AB032200
H28 H28 histocompatibility 28 343 8.9 NM_031367
H28 H28 histocompatibility 28 370 6.8 BC024930
H2-Aa H2-Aa histocompatibility 2, class II antigen A, 1265 12.3 AV018723
alpha
H2-Aa H2-Aa histocompatibility 2, class II antigen A, 3501 7.1 BE688749
alpha
— H2-Aa — 18 46.1 AV086906
H2-Aa H2-Aa histocompatibility 2, class II antigen A, 2137 10.8 AF119253
alpha
H2-Ab1 H2-Ab1 histocompatibility 2, class II antigen A, 421 19.9 M15848
beta 1
H2-Ab1 H2-Ab1 histocompatibility 2, class II antigen A, 950 13.2 NM_010379
beta 1
H2-Ab1 H2-Ab1 histocompatibility 2, class II antigen A, 659 18.5 M15848
beta 1
H2afx H2afx H2A histone family, member X 654 2.0 NM_010436
H2-D1 H2-D1 histocompatibility 2, D region locus 1 87 3.5 X00246
H2-D1 H2-D1 histocompatibility 2, D region locus 1 76 34.3 M34962
H2-D1 H2-D1 histocompatibility 2, D region locus 1 43 15.6 M33151
H2-D1 H2-D1 histocompatibility 2, D region locus 1 437 26.3 M86502
H2-D1 H2-D1 histocompatibility 2, D region locus 1 43 11.3 M83244
H2-D1 H2-D1 histocompatibility 2, D region locus 1 2224 6.2 NM_010380
H2-D1 H2-D1 histocompatibility 2, D region locus 1 228 52.6 L36068
H2-D1 H2-D1 histocompatibility 2, D region locus 1 152 50.7 M69068
— H2-DMa — 6 16.9 BB425495
H2-DMa H2-DMa histocompatibility 2, class II, locus DMa 261 20.9 NM_010386
H2-DMb1 H2-DMb1 histocompatibility 2, class II, locus Mb1 121 38.0 NM_010388
H2-DMb1 H2-DMb1 histocompatibility 2, class II, locus Mb1 159 45.2 BB734586
H2-DMb1 H2-DMb1 histocompatibility 2, class II, locus Mb1 347 16.8 NM_010388
H2-DMb1 H2-DMb1 histocompatibility 2, class II, locus Mb1 116 19.8 NM_010387
H2-DMb1 H2-DMb1 histocompatibility 2, class II, locus Mb1 87 53.8 BB734586
H2-Ea H2-Ea histocompatibility 2, class II antigen E 103 3.7 U13648
alpha
H2-Ea H2-Ea histocompatibility 2, class II antigen E 63 6.4 U13648
alpha
H2-Eb1 H2-Eb1 histocompatibility 2, class II antigen E 1760 8.6 NM_010382
beta
H2-K H2-K histocompatibility 2, K region 136 5.9 J00406
H2-K H2-K1 histocompatibility 2, K region 626 22.5 L23495
— H2-K1 MHC l = H-2Kd homolog {alternatively 435 45.5 S70184
spliced, deletion of exon 3} [mice, DBA/2,
L1210 lymphoma, mRNA Mutant, 855 nt]
H2-K H2-K1 histocompatibility 2, K region 606 23.9 BC011306
H2-M3 H2-M3 histocompatibility 2, M region locus 3 261 4.8 NM_013819
H2-Oa H2-Oa histocompatibility 2, O region alpha locus 56 6.1 NM_008206
H2-Ob H2-Ob histocompatibility 2, O region beta locus 38 4.4 BG144448
H2-Q1 H2-Q1 histocompatibility 2, Q region locus 1 125 3.7 M58156
H2-Q1 H2-Q1 histocompatibility 2, Q region locus 1 35 22.6 BC010602
H2-K H2-Q5 histocompatibility 2, K region 20 18.3 NM_010393
H2-Q7 H2-Q7 histocompatibility 2, Q region locus 7 20 14.9 AK013097
H2-Q7 H2-Q7 histocompatibility 2, Q region locus 7 37 78.5 M29881
H2-T10 H2-T10 histocompatibility 2, T region locus 10 2355 4.3 NM_010395
H2-T23 H2-T23 histocompatibility 2, T region locus 23 2198 8.0 NM_010398
— H2-T23 Mus musculus 2 days neonate thymus 71 6.6 NM_010398
thymic cells cDNA, RIKEN full-length
enriched library, clone: C920026N01
product: weakly similar to H-2 CLASS I
HISTOCOMPATIBILITY ANTIGEN, D-37
ALPHA CHAIN PRECURSOR [Mus
musculus], full insert sequence
H2-T24 H2-T24 histocompatibility 2, T region locus 24 109 3.1 L22338
Has2 Has2 hyaluronan synthase 2 37 2.5 NM_008216
Havcr1 Havcr1 hepatitis A virus cellular receptor 1 700 7.0 NM_134248
Havcr1 Havcr1 hepatitis A virus cellular receptor 1 1015 7.8 BM211416
Havcr2 Havcr2 hepatitis A virus cellular receptor 2 39 4.7 AF450241
— Hck Mus musculus transcribed sequences 28 2.2 BM246401
Hck Hck hemopoietic cell kinase 117 17.9 NM_010407
Hcph Hcph hemopoietic cell phosphatase 617 4.1 NM_013545
Hells Hells helicase, lymphoid specific 65 10.4 NM_008234
4930568P13Rik Hemp1 RIKEN cDNA 4930568P13 gene 36 25.3 BM238906
4930568P13Rik Hemp1 RIKEN cDNA 4930568P13 gene 147 4.8 BM238906
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 gene 217 12.8 AI639807
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 gene 64 18.0 AK015214
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 gene 161 25.4 AW208668
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 gene 72 20.4 AI639807
Hesx1 Hesx1 homeo box gene expressed in ES cells 76 4.2 NM_010420
Hgf Hgf hepatocyte growth factor 74 2.7 D10212
Hgf Hgf hepatocyte growth factor 49 3.0 AF042856
Hgf Hgf hepatocyte growth factor 37 2.8 BB476818
— Hif1a Mus musculus transcribed sequences 10 3.9 BB409314
Hist1h2ae Hist1h2ae histone 1, H2ae 525 24.6 W91024
Hivep2 Hivep2 human immunodeficiency virus type I 138 2.0 AW321867
enhancer binding protein 2
Hk2 Hk2 hexokinase 2 79 7.1 NM_013820
Hk3 Hk3 hexokinase 3 106 6.7 BB334625
— Hk3 — 97 14.9 BB324660
Hmgb2 Hmgb2 high mobility group box 2 544 7.3 X67668
Hmgb2 Hmgb2 high mobility group box 2 337 9.1 C85885
Hn1 Hn1 hematological and neurological 327 4.3 NM_008258
expressed sequence 1
Hn1 Hn1 hematological and neurological 236 5.6 NM_008258
expressed sequence 1
— Hnrpa1 Mus musculus transcribed sequence with 705 3.1 BI663320
strong similarity to protein
ref: NP_002127.1 (H. sapiens)
heterogeneous nuclear ribonucleoprotein
A1, isoform a; nuclear ribonucleoprotein
particle A1 protein; helix-destabilizing
protein; single-strand DNA-binding
protein UP1; heterogeneous nuclear
ribonucleoprotein core protein A1;
heterogeneous nuclear ribonucleoprotein
A1B protein; heterogeneous nuclear
ribonucleoprotein B2 protein [Homo
sapiens]
Hnrpa1 Hnrpa1; Hdp; heterogeneous nuclear ribonucleoprotein 1077 2.1 AK007802
hnrnp-A1; A1
D15Ertd119e
2610510D13Rik Hnrpa3 RIKEN cDNA 2610510D13 gene 2441 2.0 BC024454
Hnrpdl Hnrpdl heterogeneous nuclear ribonucleoprotein 787 2.3 NM_016690
D-like
Hp Hp haptoglobin 53 9.9 NM_017370
Hpse Hpse heparanase 32 22.8 BG094050
Hrasls3 Hrasls3 HRAS like suppressor 3 504 16.5 BC024581
Hrb Hrb HIV-1 Rev binding protein 4 2.5 BG068396
4930534K13Rik Ibrdc3 RIKEN cDNA 4930534K13 gene 280 7.3 AK015966
4930534K13Rik Ibrdc3 RIKEN cDNA 4930534K13 gene 430 6.2 BG064140
Icam1 Icam1 intercellular adhesion molecule 440 10.2 BC008626
Icos Icos inducible T-cell co-stimulator 68 9.8 AV313923
Icsbp1 Icsbp1 interferon consensus sequence binding 228 9.9 BG069095
protein 1
Icsbp1 Icsbp1 interferon consensus sequence binding 432 10.0 BG069095
protein 1
Ier5 Ier5 immediate early response 5 347 3.1 BF147705
Ifi1 Ifi1 interferon inducible protein 1 1151 15.4 NM_008326
Ifi202b Ifi202b interferon activated gene 202B 118 46.5 NM_011940
Ifi202b Ifi202b interferon activated gene 202B 93 42.5 AV229143
Ifi203 Ifi203 interferon activated gene 203 63 17.8 NM_008328
Ifi203 Ifi203 interferon activated gene 203 177 9.1 BC008167
Ifi16 Ifi204 interferon, gamma-inducible protein 16 22 24.8 NM_008329
Ifi205 Ifi205 interferon activated gene 205 12 140.4 M74124
Ifi205 Ifi205 interferon activated gene 205 30 151.7 M74124
Ifi205 Ifi205 interferon activated gene 205 38 79.7 AI481797
Ifi205 Ifi205 interferon activated gene 205 76 102.7 AI481797
2310061N23Rik Ifi27 RIKEN cDNA 2310061N23 gene 219 8.2 AY090098
Ifi30 Ifi30 interferon gamma inducible protein 30 3381 2.4 NM_023065
2010008K16Rik Ifi35 RIKEN cDNA 2010008K16 gene 1277 6.0 AW986054
2010008K16Rik Ifi35 RIKEN cDNA 2010008K16 gene 377 4.5 BC008158
2010008K16Rik Ifi35 RIKEN cDNA 2010008K16 gene 371 2.5 AW986054
A430056A10Rik Ifi44 RIKEN cDNA A430056A10 gene 439 5.0 BB329808
9130009C22Rik Ifih1 RIKEN cDNA 9130009C22 gene 506 5.4 AY075132
Ifit1 Ifit1 interferon-induced protein with 93 18.5 NM_008331
tetratricopeptide repeats 1
Ifit2 Ifit2 interferon-induced protein with 271 33.8 NM_008332
tetratricopeptide repeats 2
Ifit3 Ifit3 interferon-induced protein with 761 6.3 NM_010501
tetratricopeptide repeats 3
1110036C17Rik Ifitm1 RIKEN cDNA 1110036C17 gene 622 4.0 BC027285
1110004C05Rik Ifitm3 RIKEN cDNA 1110004C05 gene 3701 4.2 BC010291
A330075D07 Ifitm6 hypothetical protein A330075D07 34 10.6 BB193024
Ifnar2 Ifnar2 interferon (alpha and beta) receptor 2 107 3.0 Y09864
Ifnar2 Ifnar2 interferon (alpha and beta) receptor 2 155 2.7 BB522265
Ifnar2 Ifnar2 interferon (alpha and beta) receptor 2 977 2.4 AF013486
Ifng Ifng interferon gamma 32 30.3 K00083
Ifngr Ifngr1 interferon gamma receptor 572 2.0 NM_010511
Ifrd1 Ifrd1 interferon-related developmental 463 3.0 NM_013562
regulator 1
Igf1 Igf1 insulin-like growth factor 1 606 2.0 BG075165
Igf1 Igf1 insulin-like growth factor 1 184 2.7 NM_010512
Igf1 Igf1 insulin-like growth factor 1 236 2.2 AF440694
Igf1 Igf1 insulin-like growth factor 1 398 3.1 BG092677
Igh-6 Igh-6 immunoglobulin heavy chain 6 (heavy 140 12.8 BB226392
chain of IgM)
Igh-6 Igh-6 immunoglobulin heavy chain 6 (heavy 269 6.0 AI326478
chain of IgM)
Igsf6 Igsf6 immunoglobulin superfamily, member 6 8 25.4 NM_030691
Igsf7 Igsf7 immunoglobulin superfamily, member 7 101 7.0 AF251705
— Igtp Mus musculus 13 days embryo lung 35 14.3 BB485297
cDNA, RIKEN full-length enriched library,
clone: D430030N05 product: unknown
EST, full insert sequence
Igtp Igtp interferon gamma induced GTPase 905 25.9 NM_018738
AI481100 Igtp expressed sequence AI481100 365 30.9 NM_019440
Ii Ii Ia-associated invariant chain 3790 6.2 BC003476
AW111922 Iigp1 expressed sequence AW111922 885 36.6 BM239828
AW111922 Iigp1 expressed sequence AW111922 361 53.7 BM239828
Il11 Il11 interleukin 11 43 4.4 NM_008350
Il12b Il12b interleukin 12b 29 4.2 AF128214
Il12rb1 Il12rb1 interleukin 12 receptor, beta 1 35 5.5 NM_008353
Il18 Il18 interleukin 18 330 2.1 NM_008360
Il18bp Il18bp interleukin 18 binding protein 122 33.6 AF110803
Il18rap Il18rap interleukin 18 receptor accessory protein 12 8.4 NM_010553
Il1b Il1b interleukin 1 beta 118 4.7 BC011437
Il1rn Il1rn interleukin 1 receptor antagonist 40 14.3 M57525
Il1rn Il1rn interleukin 1 receptor antagonist 99 6.6 NM_031167
Tccr Il27ra T cell cytokine receptor 28 8.2 NM_016671
Il2rb Il2rb interleukin 2 receptor, beta chain 39 12.3 BE634648
Il4i1 Il4i1 interleukin 4 induced 1 46 3.9 NM_010215
Il4ra Il4ra interleukin 4 receptor, alpha 203 2.8 NM_010557
Il6 Il6 interleukin 6 15 20.8 NM_031168
Il7r Il7r interleukin 7 receptor 72 4.6 AI573431
Incenp Incenp inner centromere protein 80 4.4 BI410774
Incenp Incenp inner centromere protein 192 9.0 BB418702
Indo Indo indoleamine-pyrrole 2,3 dioxygenase 15 6.7 NM_008324
Inhbb Inhbb inhibin beta-B 98 4.2 BB253137
Inpp5d Inpp5d inositol polyphosphate-5-phosphatase D 170 4.7 U39203
Irak3 Irak3 interleukin-1 receptor-associated kinase 3 43 2.8 AV228493
Irak4 Irak4 interleukin-1 receptor-associated kinase 4 63 3.2 BM220651
B430217B02Rik Irf1 RIKEN cDNA B430217B02 gene 665 15.7 NM_008390
— Irf2 — 53 4.9 AI606908
Irf5 Irf5 interferon regulatory factor 5 205 2.7 NM_012057
Irf7 Irf7 interferon regulatory factor 7 198 9.8 NM_016850
Irg1 Irg1 immunoresponsive gene 1 9 80.3 L38281
Isg20 Isg20 interferon-stimulated protein 119 4.7 BC022751
Isgf3g Isgf3g interferon dependent positive acting 327 3.6 NM_008394
transcription factor 3 gamma
Itga4 Itga4 integrin alpha 4 45 4.4 BB284583
Itga4 Itga4 integrin alpha 4 19 8.5 NM_010576
— Itga4 Mus musculus adult retina cDNA, RIKEN 138 7.9 BB205589
full-length enriched library,
clone: A930029I05 product: unknown EST,
full insert sequence
Itgal Itgal integrin alpha L 118 9.3 BI554446
Itgam Itgam integrin alpha M 16 12.4 NM_008401
Itgax Itgax integrin alpha X 80 11.9 NM_021334
Itgb2 Itgb2 integrin beta 2 178 28.7 NM_008404
Jak2 Jak2 Janus kinase 2 882 2.4 NM_008413
Jak2 Jak2 Janus kinase 2 353 3.1 NM_008413
Smcx Jarid1c selected mouse cDNA on the X 35 2.1 BB165753
Jun Jun Jun oncogene 559 2.7 NM_010591
Kcnab2 Kcnab2 potassium voltage-gated channel, 35 9.0 U31908
shaker-related subfamily, beta member 2
D7Ertd764e Kcnk6 DNA segment, Chr 7, ERATO Doi 764, 139 3.5 BG069589
expressed
Kcnn4 Kcnn4 potassium intermediate/small 45 28.2 BG865910
conductance calcium-activated channel,
subfamily N, member 4
— Kcnq5 Mus musculus transcribed sequences 17 2.9 BB162318
Khdrbs1 Khdrbs1 KH domain containing, RNA binding, 290 7.1 BB752997
signal transduction associated 1
Kif11 Kif11 kinesin family member 11 41 6.6 BB827235
— Kif11 Mus musculus transcribed sequences 68 5.0 BM234447
Kif11 Kif11 kinesin family member 11 89 4.5 BB827235
Kif18a Kif18a kinesin family member 18A 63 2.8 BC016095
Kif20a Kif20a kinesin family member 20A 65 4.3 NM_009004
Kif21b Kif21b kinesin family member 21B 113 3.2 AV122249
Kif22 Kif22 kinesin family member 22 248 8.4 BB251322
Kif2c Kif2c kinesin family member 2C 43 8.7 BB104669
Kif2c Kif2c kinesin family member 2C 74 4.4 NM_134471
Kif4 Kif4 kinesin family member 4 71 3.2 NM_008446
Klf5 Klf5 Kruppel-like factor 5 164 2.4 BG069607
KLHL6 Klhl6 kelch-like 6 297 3.1 BM247104
Klra2 Klra2 killer cell lectin-like receptor, subfamily A, 30 14.3 NM_008462
member 2
Klra7 Klra7 killer cell lectin-like receptor, subfamily A, 7 7.9 U10095
member 7
Klra8 Klra8 killer cell lectin-like receptor, subfamily A, 17 5.5 U12889
member 8
Klra3 Klra9 killer cell lectin-like receptor, subfamily A, 68 6.5 U49865
member 3
Klrb1d Klrb1d killer cell lectin-like receptor subfamily B 11 4.2 AF342896
member 1D
Klrb1d Klrb1d killer cell lectin-like receptor subfamily B 25 4.6 AF342896
member 1D
Klrb1d Klrb1d killer cell lectin-like receptor subfamily B 20 9.8 NM_008526
member 1D
Klrb1d Klrb1d killer cell lectin-like receptor subfamily B 17 10.2 AV294178
member 1D
Klrc1 Klrc1 killer cell lectin-like receptor subfamily C, 6 19.3 AF106009
member 1
Klre1 Klre1 killer cell lectin-like receptor family E 33 3.2 BG230222
member 1
Klrk1 Klrk1 killer cell lectin-like receptor subfamily K, 66 21.5 AF039026
member 1
Kntc1 Kntc1 kinetochore associated 1 71 4.4 AW536884
Kpna2 Kpna2 karyopherin (importin) alpha 2 1340 2.6 NM_010655
Kpna3 Kpna3 karyopherin (importin) alpha 3 449 2.0 BM213828
Kpnb1 Kpnb1 karyopherin (importin) beta 1 1298 3.3 BC004096
9030623C06Rik Krt20 RIKEN cDNA 9030623C06 gene 37 4.4 AF473907
Laf4 Laf4 lymphoid nuclear protein related to AF4 37 4.3 BQ177036
D7Bwg0421e Lair1 DNA segment, Chr 7, Brigham & 64 11.9 AK017222
Women's Genetics 0421 expressed
Laptm5 Laptm5 lysosomal-associated protein 31 4.5 BB264849
transmembrane 5
Laptm5 Laptm5 lysosomal-associated protein 173 30.9 BB218107
transmembrane 5
— Lass6 Mus musculus adult male small intestine 57 2.3 BG072448
cDNA, RIKEN full-length enriched library,
clone: 2010109K09
product: unclassifiable, full insert
sequence
Lbp Lbp lipopolysaccharide binding protein 175 3.3 NM_008489
Lck Lck lymphocyte protein tyrosine kinase 6 3.5 AA867167
Lck Lck lymphocyte protein tyrosine kinase 23 2.2 BB200032
Lck Lck lymphocyte protein tyrosine kinase 93 9.2 AA867167
Lck Lck lymphocyte protein tyrosine kinase 128 19.5 BC011474
Lcn2 Lcn2 lipocalin 2 176 29.2 X14607
Lcp1 Lcp1 lymphocyte cytosolic protein 1 231 20.8 NM_008879
Lcp1 Lcp1 lymphocyte cytosolic protein 1 515 15.0 NM_008879
Lcp2 Lcp2 lymphocyte cytosolic protein 2 48 31.8 BC006948
Lfng Lfng lunatic fringe gene homolog (Drosophila) 146 3.0 NM_008494
Lgals1 Lgals1 lectin, galactose binding, soluble 1 5227 2.9 AI642438
Lgals1 Lgals1 lectin, galactose binding, soluble 1 3962 2.8 NM_008495
— Lgals3 Mus musculus transcribed sequences 44 2.8 AI426376
Lgals3 Lgals3 lectin, galactose binding, soluble 3 2066 3.2 X16834
Ppicap Lgals3bp peptidylprolyl isomerase C-associated 1079 4.7 NM_011150
protein
Lig1 Lig1 ligase I, DNA, ATP-dependent 193 3.6 NM_010715
Gp49b Lilrb4 glycoprotein 49 B 133 22.1 U05264
Litaf Litaf LPS-induced TN factor 814 3.7 AV360881
Litaf Litaf LPS-induced TN factor 1740 4.3 AV360881
LOC207685 LOC207685 hypothetical protein LOC207685 66 5.0 AK008551
LOC207685 LOC207685 hypothetical protein LOC207685 109 2.7 AK008551
LOC209387 LOC209387 tripartite motif protein 30-like 81 9.7 BG068242
LOC209387 LOC209387 tripartite motif protein 30-like 15 20.2 BM241342
LOC223672 LOC223672 hypothetical protein LOC223672 18 25.0 BC020489
5830475I06Rik Loh11cr2a RIKEN cDNA 5830475I06 gene 588 4.9 BC004727
Lox Lox lysyl oxidase 87 7.5 M65143
Lox Lox lysyl oxidase 154 7.4 M65143
Loxl3 Loxl3 lysyl oxidase-like 3 121 3.5 NM_013586
4832412D13Rik Lrch1 RIKEN cDNA 4832412D13 gene 241 2.2 BB755336
— Lrch1 Mus musculus transcribed sequences 22 5.8 AW909485
1300008B03Rik Lrg1 RIKEN cDNA 1300008B03 gene 81 3.7 NM_029796
Lrmp Lrmp lymphoid-restricted membrane protein 72 6.9 NM_008511
Lrp1 Lrp1 low density lipoprotein receptor-related 38 2.1 AV345706
protein 1
Lrrfip1 Lrrfip1 leucine rich repeat (in FLII) interacting 837 3.0 BG069059
protein 1
AW319595 Lrrk1 expressed sequence AW319595 233 2.3 BC027199
Lsm5 Lsm5 LSM5 homolog, U6 small nuclear RNA 457 2.3 NM_025520
associated (S. cerevisiae)
Lsp1 Lsp1 lymphocyte specific 1 199 8.8 NM_019391
Lst1 Lst1 leukocyte specific transcript 1 98 18.7 U72644
Lta Lta lymphotoxin A 7 5.8 NM_010735
Ltbp2 Ltbp2 latent transforming growth factor beta 35 14.9 NM_013589
binding protein 2
Ly6c Ly6c lymphocyte antigen 6 complex, locus C 3983 2.8 NM_010741
Ly6e Ly6e lymphocyte antigen 6 complex, locus E 1793 6.8 BM245572
Ly6f Ly6f lymphocyte antigen 6 complex, locus F 24 4.3 NM_008530
Ly6i Ly6i lymphocyte antigen 6 complex, locus I 189 15.4 AF232024
Ly78 Ly78 lymphocyte antigen 78 77 3.2 NM_008533
Ly86 Ly86 lymphocyte antigen 86 165 24.1 NM_010745
Lyn Lyn Yamaguchi sarcoma viral (v-yes-1) 275 3.6 M64608
oncogene homolog
Lyn Lyn Yamaguchi sarcoma viral (v-yes-1) 585 2.9 M57697
oncogene homolog
Lyst Lyst lysosomal trafficking regulator 347 2.0 BB463428
Lyzs Lyzs lysozyme 483 27.0 AW208566
Lyzs Lyzs lysozyme 327 56.6 AV058500
— Lztfl1 Mus musculus transcribed sequence with 1043 2.1 BF320908
strong similarity to protein
ref: NP_002127.1 (H. sapiens)
heterogeneous nuclear ribonucleoprotein
A1, isoform a; nuclear ribonucleoprotein
particle A1 protein; helix-destabilizing
protein; single-strand DNA-binding
protein UP1; heterogeneous nuclear
ribonucleoprotein core protein A1;
heterogeneous nuclear ribonucleoprotein
A1B protein; heterogeneous nuclear
ribonucleoprotein B2 protein [Homo
sapiens]
Mad Mad Max dimerization protein 110 2.8 AV228517
Mad Mad Max dimerization protein 204 2.1 AV228517
Mad2l1 Mad2l1 MAD2 (mitotic arrest deficient, homolog)- 349 3.8 NM_019499
like 1 (yeast)
Mafb Mafb v-maf musculoaponeurotic fibrosarcoma 24 2.5 AW412521
oncogene family, protein B (avian)
Maff Maff v-maf musculoaponeurotic fibrosarcoma 91 2.7 BC022952
oncogene family, protein F (avian)
Map3k1 Map3k1 mitogen activated protein kinase kinase 319 2.4 L13103
kinase 1
Map4k1 Map4k1 mitogen activated protein kinase kinase 17 13.9 BB546619
kinase kinase 1
Marcks Marcks myristoylated alanine rich protein kinase 1601 2.1 AW546141
C substrate
Marcks Marcks myristoylated alanine rich protein kinase 847 2.4 AW546141
C substrate
Marcks Marcks myristoylated alanine rich protein kinase 1166 2.5 BB100920
C substrate
Mbc2 Mbc2 membrane bound C2 domain containing 279 4.2 BC011482
protein
— Mbnl1 Mus musculus transcribed sequences 96 3.8 BM201095
— Mbnl3 Mus musculus 0 day neonate lung cDNA, 104 4.0 AV306759
RIKEN full-length enriched library,
clone: E030002K20 product: similar to
MUSCLEBLIND-LIKE PROTEIN
FLJ11316/DKFZP434G2222/DJ842K24.1
[Homo sapiens], full insert sequence
Mbtps2 Mbtps2 RIKEmembrane-bound transcription 46 4.0 AV272026
factor protease, site 2
Mcl1 Mcl1 myeloid cell leukemia sequence 1 3111 2.4 BB374534
Mcl1 Mcl1 myeloid cell leukemia sequence 1 1844 2.4 BC003839
Mcm2 Mcm2 minichromosome maintenance deficient 2 257 3.3 NM_008564
mitotin (S. cerevisiae)
Mcm3 Mcm3 minichromosome maintenance deficient 3 115 5.2 C80350
(S. cerevisiae)
Mcm3 Mcm3 minichromosome maintenance deficient 3 23 15.8 BI658327
(S. cerevisiae)
Mcm3 Mcm3 minichromosome maintenance deficient 3 199 5.7 C80350
(S. cerevisiae)
Mcm3 Mcm3 minichromosome maintenance deficient 3 39 3.2 C80350
(S. cerevisiae)
Mcm3 Mcm3 minichromosome maintenance deficient 3 60 9.2 BI658327
(S. cerevisiae)
Mcm4 Mcm4 minichromosome maintenance deficient 4 211 4.5 BB447978
homolog (S. cerevisiae)
Mcm4 Mcm4 minichromosome maintenance deficient 4 356 4.1 BC013094
homolog (S. cerevisiae)
Mcm5 Mcm5 minichromosome maintenance deficient 260 9.4 AI324988
5, cell division cycle 46 (S. cerevisiae)
Mcm5 Mcm5 minichromosome maintenance deficient 160 6.2 NM_008566
5, cell division cycle 46 (S. cerevisiae)
Mcm6 Mcm6 minichromosome maintenance deficient 6 304 3.7 BB099487
(MIS5 homolog, S. pombe) (S. cerevisiae)
— Mcm7 Mus musculus adult male thymus cDNA, 766 2.0 NM_008568
RIKEN full-length enriched library,
clone: 5830410A10 product: minichromosome
maintenance deficient 7 (S. cerevisiae),
full insert sequence
— Mcm7 Mus musculus adult male thymus cDNA, 267 2.7 BB407228
RIKEN full-length enriched library,
clone: 5830410A10 product: minichromosome
maintenance deficient 7 (S. cerevisiae),
full insert sequence
— Mcm7 Mus musculus adult male thymus cDNA, 1385 2.3 BB464359
RIKEN full-length enriched library,
clone: 5830410A10 product: minichromosome
maintenance deficient 7 (S. cerevisiae),
full insert sequence
Kdt1 Mdfid kidney cell line derived transcript 1 889 2.2 U13371
Me2 Me2 malic enzyme 2, NAD(+)-dependent, 51 3.4 BM235734
mitochondrial
Me2 Me2 malic enzyme 2, NAD(+)-dependent, 129 4.1 BM235734
mitochondrial
Mefv Mefv Mediterranean fever 140 3.7 NM_019453
— Metap2 Mus musculus transcribed sequences 44 2.1 BM730703
Mfap5 Mfap5 microfibrillar associated protein 5 43 3.7 NM_015776
Mfap5 Mfap5 microfibrillar associated protein 5 67 7.2 NM_015776
— MGC58382 Mus musculus cDNA clone MGC: 58382 58 14.2 BG961961
IMAGE: 6774154, complete cds
1200016D23Rik MGC65590 RIKEN cDNA 1200016D23 gene 5 2.8 BB093351
Mgl1 Mgl1 macrophage galactose N-acetyl- 35 4.5 NM_010796
galactosamine specific lectin 1
Mglap Mglap matrix gamma-carboxyglutamate (gla) 4867 2.3 NM_008597
protein
Mki67 Mki67 antigen identified by monoclonal antibody 129 11.7 X82786
Ki 67
— Mllt3 Mus musculus transcribed sequences 24 3.0 AV381294
Mllt3 Mllt3 myeloid/lymphoid or mixed lineage- 114 2.2 AK019458
leukemia translocation to 3 homolog
(Drosophila)
Mlp Mlp MARCKS-like protein 92 2.2 BB491008
Mlp Mlp MARCKS-like protein 538 3.2 AV110584
Mmp14 Mmp14 matrix metalloproteinase 14 (membrane- 97 5.1 NM_008608
inserted)
Mmp14 Mmp14 matrix metalloproteinase 14 (membrane- 216 5.1 NM_008608
inserted)
Mmp19 Mmp19 matrix metalloproteinase 19 7 4.4 AF153199
Mmp7 Mmp7 matrix metalloproteinase 7 50 6.4 NM_010810
D930043C02Rik Mnab RIKEN cDNA D930043C02 gene 23 2.3 BM210927
D930043C02Rik Mnab RIKEN cDNA D930043C02 gene 28 2.3 AA709668
Mns1 Mns1 meiosis-specific nuclear structural protein 1 27 3.7 NM_008613
4022402H07Rik Mobk1b RIKEN cDNA 4022402H07 gene 1399 2.2 BC011285
— Mpa2l Mus musculus transcribed sequence with 191 118.4 BM241485
weak similarity to protein sp: P32456
(H. sapiens) GBP2_HUMAN Interferon-
induced guanylate-binding protein 2
(Guanine nucleotide-binding protein 2)
— Mpa2l Mus musculus transcribed sequences 339 72.1 BG092512
Mpeg1 Mpeg1 macrophage expressed gene 1 402 22.7 L20315
Mre11a Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 190 2.3 NM_018736
Ms4a1 Ms4a1 membrane-spanning 4-domains, 28 4.0 BB236617
subfamily A, member 1
Ms4a1 Ms4a1 membrane-spanning 4-domains, 17 3.7 BB236617
subfamily A, member 1
Ms4a4b Ms4a4b membrane-spanning 4-domains, 88 56.0 BB199001
subfamily A, member 4B
Ms4a4d Ms4a4d membrane-spanning 4-domains, 96 12.6 NM_025658
subfamily A, member 4D
— Ms4a6b Mus musculus adult male aorta and vein 92 3.1 BB221406
cDNA, RIKEN full-length enriched library,
clone: A530066O14 product: unknown
EST, full insert sequence
— Ms4a6b Mus musculus adult male aorta and vein 37 4.2 BB218965
cDNA, RIKEN full-length enriched library,
clone: A530066O14 product: unknown
EST, full insert sequence
Ms4a6b Ms4a6b membrane-spanning 4-domains, 126 45.7 NM_027209
subfamily A, member 6B
Ms4a6c Ms4a6c membrane-spanning 4-domains, 132 14.8 AF237910
subfamily A, member 6C
Ms4a11 Ms4a6d membrane-spanning 4-domains, 50 38.3 NM_026835
subfamily A, member 11
Ms4a11 Ms4a6d membrane-spanning 4-domains, 57 39.2 NM_026835
subfamily A, member 11
A430103C15Rik Ms4a7 RIKEN cDNA A430103C15 gene 105 5.4 BC024402
Msn Msn moesin 1945 2.3 NM_010833
Msn Msn moesin 4591 2.1 NM_010833
Msr1 Msr1 macrophage scavenger receptor 1 25 12.3 L04274
Msr1 Msr1 macrophage scavenger receptor 1 44 9.9 AA183642
Msr1 Msr1 macrophage scavenger receptor 1 58 9.8 BC003814
Mt2 Mt2 metallothionein 2 3122 2.9 AA796766
Mthfd2 Mthfd2 methylenetetrahydrofolate 134 3.6 BG076333
dehydrogenase (NAD+ dependent),
methenyltetrahydrofolate cyclohydrolase
Mthfd2 Mthfd2 methylenetetrahydrofolate 111 6.4 BG076333
dehydrogenase (NAD+ dependent),
methenyltetrahydrofolate cyclohydrolase
Mvp Mvp major vault protein 281 3.9 NM_080638
— Mvp — 396 4.1 BB139464
Mx1 Mx1 myxovirus (influenza virus) resistance 1 54 6.9 M21039
Myadm Myadm myeloid-associated differentiation marker 716 2.1 BI078799
Myb Myb myeloblastosis oncogene 10 26.7 NM_033597
Myb Myb myeloblastosis oncogene 29 7.7 NM_033597
Myb Myb myeloblastosis oncogene 5 7.0 BC011513
Myc Myc myelocytomatosis oncogene 198 3.5 BC006728
Myd88 Myd88 myeloid differentiation primary response 590 3.9 BC005591
gene 88
— Myh9 — 211 2.5 C80049
Myo1f Myo1f myosin IF 57 10.4 AK021181
Myo1f Myo1f myosin IF 16 30.8 AK021181
Myo1g Myo1g myosin IG 76 15.2 BB235320
Myo9b Myo9b myosin IXb 239 2.5 NM_015742
Nasp Nasp nuclear autoantigenic sperm protein 470 2.3 BB493242
(histone-binding)
Ncf1 Ncf1 neutrophil cytosolic factor 1 155 8.1 AI844633
Ncf2 Ncf2 neutrophil cytosolic factor 2 121 5.7 NM_010877
Ncor1 Ncor1 nuclear receptor co-repressor 1 24 2.5 AI481996
— Nefh Mus musculus mRNA for mKIAA0845 18 10.0 M35131
protein
BC034753 Neil3 cDNA sequence BC034753 29 2.1 AV316939
Nek2 Nek2 NIMA (never in mitosis gene a)-related 112 4.2 C77054
expressed kinase 2
Nek6 Nek6 NIMA (never in mitosis gene a)-related 237 2.3 BC019524
expressed kinase 6
— Net1 Mus musculus transcribed sequences 40 4.1 AV247312
Nfatc1 Nfatc1 nuclear factor of activated T-cells, 71 4.5 AF239169
cytoplasmic 1
Nfatc1 Nfatc1 nuclear factor of activated T-cells, 187 3.6 NM_016791
cytoplasmic 1
Nfatc1 Nfatc1 nuclear factor of activated T-cells, 204 2.6 BB356861
cytoplasmic 1
Nfatc2 Nfatc2 nuclear factor of activated T-cells, 112 3.7 BM122872
cytoplasmic 2
Nfkb1 Nfkb1 nuclear factor of kappa light chain gene 654 2.6 L28118
enhancer in B-cells 1, p105
Nfkb2 Nfkb2 nuclear factor of kappa light polypeptide 141 3.9 AF155372
gene enhancer in B-cells 2, p49/p100
Nfkbia Nfkbia nuclear factor of kappa light chain gene 4502 3.1 AI462015
enhancer in B-cells inhibitor, alpha
Nfkbia Nfkbia nuclear factor of kappa light chain gene 666 3.2 AI462015
enhancer in B-cells inhibitor, alpha
Nfkbie Nfkbie nuclear factor of kappa light polypeptide 122 4.5 AK011965
gene enhancer in B-cells inhibitor,
epsilon
— Nfkbie — 194 9.7 BB820441
AA408868 Nfkbiz expreexpressed sequence AA408868 82 10.1 BM240058
AA408868 Nfkbiz expreexpressed sequence AA408868 117 5.3 AB026551
AA408868 Nfkbiz expreexpressed sequence AA408868 169 10.8 AB026551
Ngfr Ngfr nerve growth factor receptor (TNFR 32 8.3 BB151515
superfamily, member 16)
Niban Niban niban protein 87 3.4 NM_022018
Nical Nical NEDD9 interacting protein with calponin 22 6.0 BB209438
homology and LIM domains
Nin Nin ninein 190 2.3 AK014241
Nkg7 Nkg7 natural killer cell group 7 sequence 55 36.5 NM_024253
Nktr Nktr natural killer tumor recognition sequence 133 2.2 AW987751
Nmi Nmi N-myc (and STAT) interactor 687 6.7 BC002019
Nnmt Nnmt nicotinamide N-methyltransferase 53 6.6 AK006371
Nol5a Nol5a nucleolar protein 5A 326 2.4 BF660256
Nol5a Nol5a nucleolar protein 5A 436 2.2 BM249243
Npc2 Npc2 Niemann Pick type C2 100 3.9 BG071996
— Nr4a3 Mus musculus transcribed sequences 20 7.2 BE692107
Nr6a1 Nr6a1 nuclear receptor subfamily 6, group A, 46 2.0 U09563
member 1
Nras Nras; N-ras neuroblastoma ras oncogene 462 2.4 AK010412
Nrf1 Nrf1 nuclear respiratory factor 1 97 2.1 BM221378
2310014H01Rik Nrm RIKEN cDNA 2310014H01 gene 58 3.1 NM_134122
Nrn1 Nrn1 neuritin 1 81 2.8 AK003046
— Nrp1 Mus musculus transcribed sequences 193 2.0 AV291009
— Nt5c2 Mus musculus transcribed sequences 41 2.8 AU017183
AW541137 Nup107 expressed sequence AW541137 242 2.1 BC004655
Nup153 Nup153 nucleoporin 153 150 2.3 C88147
Nup210 Nup210 nucleoporin 210 356 3.1 NM_018815
Nupr1 Nupr1 nuclear protein 1 743 2.1 NM_019738
Oact1 Oact1 O-acyltransferase (membrane bound) 84 3.8 AV366860
domain containing 1
Oas1g Oas1a 2′-5′ oligoadenylate synthetase 1G 345 6.9 BC018470
Oasl1 Oasl1 2′-5′ oligoadenylate synthetase-like 1 174 4.0 AB067533
Oasl2 Oasl2 2′-5′ oligoadenylate synthetase-like 2 209 17.4 BQ033138
Olfr56 Olfr56 olfactory receptor 56 336 39.5 NM_008330
Olr1 Olr1 oxidized low density lipoprotein (lectin- 8 7.9 NM_138648
like) receptor 1
A130090K04Rik Oprm1 RIKEN cDNA A130090K04 gene 347 3.1 BQ176089
Osmr Osmr oncostatin M receptor 96 5.0 AB015978
Osmr Osmr oncostatin M receptor 286 4.7 AB015978
— P2rx7 Mus musculus transcribed sequences 46 2.7 AI552982
P2ry10 P2ry10 purinergic receptor P2Y, G-protein 19 18.0 AK020001
coupled 10
P2ry12 P2ry12 purinergic receptor P2Y, G-protein 32 3.2 AK013804
coupled 12
Gpr86 P2ry13 G protein-coupled receptor 86 68 4.5 AK008013
Gpr105 P2ry14 G protein-coupled receptor 105 220 2.2 AF177211
P2ry6 P2ry6 pyrimidinergic receptor P2Y, G-protein 110 5.1 BC027331
coupled, 6
— Pabpc1 Mus musculus 0 day neonate thymus 63 2.0 AW552076
cDNA, RIKEN full-length enriched library,
clone: A430039M01 product: unknown
EST, full insert sequence
Padi2 Padi2 peptidyl arginine deiminase, type II 110 2.1 NM_008812
Panx1 Panx1 pannexin 1 88 3.2 NM_019482
5330431N24Rik Parp11 RIKEN cDNA 5330431N24 gene 264 3.1 BB026163
BC021340 Parp14 cDNA sequence BC021340 256 16.1 BC021340
Adprtl3 Parp3 ADP-ribosyltransferase (NAD+; poly 527 2.1 AW990611
(ADP-ribose polymerase)-like 3
Adprtl3 Parp3 ADP-ribosyltransferase (NAD+; poly 1373 2.6 BC014870
(ADP-ribose polymerase)-like 3
— Parp8 Mus musculus 13 days embryo forelimb 123 2.3 C85455
cDNA, RIKEN full-length enriched library,
clone: 5930433N17 product: unknown
EST, full insert sequence
BC003281 Parp9 cDNA sequence BC003281 460 12.0 NM_030253
1110035O14Rik Pbef1 RIKEN cDNA 1110035O14 gene 2754 2.4 AW989410
D14Ertd732e Pbk DNA segment, Chr 14, ERATO Doi 732, 200 3.2 NM_023209
expressed
Pcna Pcna proliferating cell nuclear antigen 3700 2.3 BC010343
Arpc1b Pdap1 actin related protein ⅔ complex, subunit 690 6.1 BE979985
1B
Pdcd1lg1 Pdcd1lg1 programmed cell death 1 ligand 1 73 45.1 NM_021893
Pdcd1lg2 Pdcd1lg2 programmed cell death 1 ligand 2 57 5.6 NM_021396
Pde4b Pde4b phosphodiesterase 4B, cAMP specific 76 2.9 BG793493
Pdk4 Pdk4 pyruvate dehydrogenase kinase, 283 3.1 NM_013743
isoenzyme 4
Pdlim1 Pdlim1 PDZ and LIM domain 1 (elfin) 272 2.6 NM_016861
Ril Pdlim4 reversion induced LIM gene 63 3.6 NM_019417
Peli1 Peli1 pellino 1 476 2.8 BC016515
Per1 Per1 period homolog 1 (Drosophila) 62 3.9 AF022992
Pfc Pfc properdin factor, complement 24 16.5 BB800282
Pfkfb3 Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6- 164 3.4 NM_133232
biphosphatase 3
Pfkp Pfkp phosphofructokinase, platelet 1402 2.7 NM_019703
Phemx Phemx pan hematopoietic expression 41 3.8 AF175771
4933417L10Rik Phf11 RIKEN cDNA 4933417L10 gene 301 4.8 AV280841
E130113K22Rik Phf20l1 RIKEN cDNA E130113K22 gene 114 2.1 AV349060
B2m Phf20l1 beta-2 microglobulin 13469 2.0 BF715219
4931428F02Rik Phf6 RIKEN cDNA 4931428F02 gene 187 2.5 AA275278
4931428F02Rik Phf6 RIKEN cDNA 4931428F02 gene 151 2.4 BG073473
Pigr Pigr polymeric immunoglobulin receptor 3030 4.4 AV027632
Pigr Pigr polymeric immunoglobulin receptor 2667 3.0 NM_011082
Pik3ap1 Pik3ap1 phosphoinositide-3-kinase adaptor 64 7.8 BI684288
protein 1
Pik3cd Pik3cd phosphatidylinositol 3-kinase catalytic 111 4.7 BB700084
delta polypeptide
Pik3cg Pik3cg phosphoinositide-3-kinase, catalytic, 146 2.6 BB205102
gamma polypeptide
Pik3r1 Pik3r1 phosphatidylinositol 3-kinase, regulatory 564 2.8 M60651
subunit, polypeptide 1 (p85 alpha)
— Pik3r5 Mus musculus transcribed sequences 41 5.0 AV230647
Pilra Pilra paired immunoglobin-like type 2 receptor 108 4.3 BB775785
alpha
Pim1 Pim1 proviral integration site 1 546 4.2 BE631223
Pip5k2a Pip5k2a phosphatidylinositol-4-phosphate 5- 104 2.6 AK012196
kinase, type II, alpha
Pip5k2a Pip5k2a phosphatidylinositol-4-phosphate 5- 420 3.0 AK012196
kinase, type II, alpha
Pira10 Pira6 paired-Ig-like receptor A10 69 15.0 NM_011093
— Pira6 — 10 15.5 NM_011087
Pirb Pirb paired-Ig-like receptor B 13 47.9 U96693
Pitpnm Pitpnm1 phosphatidylinositol membrane- 461 2.1 BB206460
associated
Pkib Pkib protein kinase inhibitor beta, cAMP 44 3.8 AV047342
dependent, testis specific
Pla2g4a Pla2g4a phospholipase A2, group IVA (cytosolic, 270 4.4 NM_008869
calcium-dependent)
Pla2g7 Pla2g7 phospholipase A2, group VII (platelet- 338 5.8 AK005158
activating factor acetylhydrolase, plasma)
Plac8 Plac8 placenta-specific 8 756 14.2 AF263458
— Plagl2 Mus musculus transcribed sequence with 33 2.6 BF584971
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
Plagl2 Plagl2 pleiomorphic adenoma gene-like 2 49 3.4 NM_018807
Plcg2 Plcg2 phospholipase C, gamma 2 521 2.1 AW546508
Plcl2 Plcl2 phospholipase C-like 2 144 5.4 BM207017
Plekha2 Plekha2 pleckstrin homology domain-containing, 346 2.3 NM_031257
family A (phosphoinositide binding
specific) member 2
Plekha2 Plekha2 pleckstrin homology domain-containing, 139 2.0 BE852755
family A (phosphoinositide binding
specific) member 2
Plekha2 Plekha2 pleckstrin homology domain-containing, 611 3.1 NM_031257
family A (phosphoinositide binding
specific) member 2
2410005C22Rik Plekha4 RIKEN cDNA 2410005C22 gene 46 3.2 BC024961
Cnk Plk3 cytokine inducible kinase 117 2.2 BM947855
Stk18 Plk4 serine/threonine kinase 18 128 2.7 BB706079
Stk18 Plk4 serine/threonine kinase 18 116 4.9 AI385771
Plp2 Plp2 proteolipid protein 2 1503 2.0 AK012816
Plxnc1 Plxnc1 plexin C1 30 3.2 BB476707
Plxnc1 Plxnc1 plexin C1 126 2.9 BB476707
Plxnc1 Plxnc1 plexin C1 48 5.5 BB476707
Pnp Pnp purine-nucleoside phosphorylase 4116 2.2 AK008143
Pola1 Pola1 polymerase (DNA directed), alpha 1 155 2.6 NM_008892
Pold1 Pold1 polymerase (DNA directed), delta 1, 164 2.1 BC009128
catalytic subunit
Pold3 Pold3 polymerase (DNA-directed), delta 3, 223 1.9 AK010805
accessory subunit
Pole2 Pole2 polymerase (DNA directed), epsilon 2 181 3.2 AF036898
(p59 subunit)
Polh Polh polymerase (DNA directed), eta (RAD 30 150 3.5 BB066090
related)
Pou2af1 Pou2af1 POU domain, class 2, associating factor 1 15 9.4 NM_011136
Ppfia4 Ppfia4; protein tyrosine phosphatase, receptor 24 4.5 AK003571
1110008G13Rik type, f polypeptide (PTPRF), interacting
protein (liprin), alpha 4
2410005L11Rik Ppil5 RIKEN cDNA 2410005L11 gene 9 3.0 BG067404
Ppp1r12a Ppp1r12a protein phosphatase 1, regulatory 1000 2.3 AV309184
(inhibitor) subunit 12A
— Ppp1r12a Mus musculus 7 days embryo whole 86 2.7 BB410003
body cDNA, RIKEN full-length enriched
library, clone: C430016H01
product: unknown EST, full insert
sequence
Ppp1r12a Ppp1r12a protein phosphatase 1, regulatory 550 2.0 BI653999
(inhibitor) subunit 12A
Ppp1r12a Ppp1r12a protein phosphatase 1, regulatory 641 2.2 AV309184
(inhibitor) subunit 12A
— Ppt1 Mus musculus 12 days embryo spinal 60 3.0 BB461203
ganglion cDNA, RIKEN full-length
enriched library, clone: D130070K05
product: unknown EST, full insert
sequence
Prdm1 Prdm1 PR domain containing 1, with ZNF 157 2.1 NM_007548
domain
Prg Prg1 proteoglycan, secretory granule 2020 4.9 NM_011157
Prim2 Prim2 DNA primase, p58 subunit 137 2.2 NM_008922
Prkcb Prkcb1 protein kinase C, beta 27 5.8 BF660388
Prkch Prkch protein kinase C, eta 412 2.7 BM243756
Prkch Prkch protein kinase C, eta 259 3.4 NM_008856
Prkcq Prkcq protein kinase C, theta 159 3.0 AB062122
AI325941 Prkd2 expressed sequence AI325941 151 2.2 BB204677
AI325941 Prkd2 expressed sequence AI325941 103 2.7 AW557946
Prkr Prkr protein kinase, interferon-inducible 165 5.0 BE911144
double stranded RNA dependent
Procr Procr protein C receptor, endothelial 163 4.7 NM_011171
Pros1 Pros1 protein S (alpha) 445 2.0 Z25469
Prrx1 Prrx1 paired related homeobox 1 24 2.0 BB051738
Pscd4 Pscd4 pleckstrin homology, Sec7 and coiled/coil 22 18.8 AK010908
domains 4
Pscdbp Pscdbp pleckstrin homology, Sec7 and coiled-coil 682 3.6 BC007144
domains, binding protein
BC046518 Psd4 cDNA sequence BC046518 122 2.2 BM221809
Psma6 Psma6 proteasome (prosome, macropain) 12 2.8 AA189256
subunit, alpha type 6
Psmb10 Psmb10 proteasome (prosome, macropain) 525 14.7 NM_013640
subunit, beta type 10
— Psmb2 Mus musculus 10 days neonate 38 2.4 BM201103
cerebellum cDNA, RIKEN full-length
enriched library, clone: B930059K21
product: unknown EST, full insert
sequence
Psmb8 Psmb8 proteosome (prosome, macropain) 461 27.5 NM_010724
subunit, beta type 8 (large multifunctional
protease 7)
Psmb8 Psmb8 proteosome (prosome, macropain) 17 24.0 AV068122
subunit, beta type 8 (large multifunctional
protease 7)
Tap1 Psmb9 transporter 1, ATP-binding cassette, sub- 127 29.5 AW048052
family B (MDR/TAP)
Psmb9 Psmb9 proteosome (prosome, macropain) 298 30.2 NM_013585
subunit, beta type 9 (large multifunctional
protease 2)
Psme1 Psme1 proteasome (prosome, macropain) 28 2901 3.1 NM_011189
subunit, alpha
Psme2 Psme2 proteasome (prosome, macropain) 28 1669 5.3 NM_011190
subunit, beta
Ptger2 Ptger2 prostaglandin E receptor 2 (subtype EP2) 19 13.1 BC005440
Ptger4 Ptger4 prostaglandin E receptor 4 (subtype EP4) 51 2.8 NM_008965
Ptger4 Ptger4 prostaglandin E receptor 4 (subtype EP4) 259 5.0 BC011193
Ptgs2 Ptgs2 prostaglandin-endoperoxide synthase 2 32 4.4 M94967
Ptgs2 Ptgs2 prostaglandin-endoperoxide synthase 2 31 9.3 M94967
Ptk9l Ptk9l protein tyrosine kinase 9-like (A6-related 125 3.4 AK002699
protein)
Ptk9l Ptk9l protein tyrosine kinase 9-like (A6-related 328 3.8 BB397672
protein)
Ptpn12 Ptpn12 protein tyrosine phosphatase, non- 1107 2.2 X63440
receptor type 12
Ptpn18 Ptpn18 protein tyrosine phosphatase, non- 338 2.9 NM_011206
receptor type 18
Ptprc Ptprc protein tyrosine phosphatase, receptor 516 18.2 NM_011210
type, C
— Ptprc Mus musculus 16 days neonate thymus 28 10.1 BM239436
cDNA, RIKEN full-length enriched library,
clone: A130082N01
product: unclassifiable, full insert
sequence
Ptprcap Ptprcap protein tyrosine phosphatase, receptor 140 7.5 NM_016933
type, C polypeptide-associated protein
Ptpre Ptpre protein tyrosine phosphatase, receptor 102 4.5 U35368
type, E
Ptpre Ptpre protein tyrosine phosphatase, receptor 73 3.6 U35368
type, E
Pttg1 Pttg1 pituitary tumor-transforming 1 408 2.3 AF069051
9130417A21Rik Pycard RIKEN cDNA 9130417A21 gene 396 6.5 BG084230
Pycs Pycs pyrroline-5-carboxylate synthetase 136 2.9 BF148128
(glutamate gamma-semialdehyde
synthetase)
Pycs Pycs pyrroline-5-carboxylate synthetase 99 6.6 BB251523
(glutamate gamma-semialdehyde
synthetase)
2010317E03Rik Pyp RIKEN cDNA 2010317E03 gene 1519 2.9 NM_026438
Qpct Qpct glutaminyl-peptide cyclotransferase 27 3.8 BB150720
(glutaminyl cyclase)
Rab19 Rab19 RAB19, member RAS oncogene family 108 2.8 BM241400
Rab32 Rab32 RAB32, member RAS oncogene family 564 2.6 NM_026405
Rab37 Rab37 RAB37, member of RAS oncogene family 43 2.1 BB433704
D330025I23Rik Rab8b RIKEN cDNA D330025I23 gene 840 4.1 BM214169
Rac2 Rac2 RAS-related C3 botulinum substrate 2 169 10.9 NM_009008
Rad18 Rad18 RAD18 homolog (S. cerevisiae) 73 2.3 BC011120
Rad18 Rad18 RAD18 homolog (S. cerevisiae) 18 4.2 BB530954
Rad23b Rad23b RAD23b homolog (S. cerevisiae) 21 2.4 BB482313
Rad54l Rad54l RAD54 like (S. cerevisiae) 17 8.1 AV310220
Ramp1 Ramp1 receptor (calcitonin) activity modifying 66 2.3 NM_016894
protein 1
Ranbp2 Ranbp2 RAN binding protein 2 61 2.6 BB208180
Rap2b Rap2b RAP2B, member of RAS oncogene 60 3.4 BB390705
family
Rap2b Rap2b RAP2B, member of RAS oncogene 196 2.7 BB645629
family
Rap2c Rap2c RAP2C, member of RAS oncogene 464 2.0 AK008416
family
Rap2c Rap2c RAP2C, member of RAS oncogene 415 2.2 AK008416
family
Rasa3 Rasa3 RAS p21 protein activator 3 142 4.6 NM_009025
Rasd1 Rasd1 RAS, dexamethasone-induced 1 136 4.7 BB217136
Rasgrp1 Rasgrp1 RAS guanyl releasing protein 1 181 3.2 BE691356
Rassf4 Rassf4 Ras association (RaIGDS/AF-6) domain 28 10.0 AV291679
family 4
Rbl1 Rbl1 retinoblastoma-like 1 (p107) 314 5.8 U27177
Rbl1 Rbl1 retinoblastoma-like 1 (p107) 59 3.2 U27178
Rbm3 Rbm3 RNA binding motif protein 3 193 2.5 AK011224
Rbmxrt Rbmxrt RNA binding motif protein, X 887 2.1 NM_009033
chromosome retrogene
Rcn Rcn1 reticulocalbin 286 4.2 NM_009037
Refbp2 Refbp2 RNA and export factor binding protein 2 611 2.1 NM_019484
Rel Rel reticuloendotheliosis oncogene 24 3.8 NM_009044
Relb Relb avian reticuloendotheliosis viral (v-rel) 109 3.0 NM_009046
oncogene related B
Rfc3 Rfc3 replication factor C (activator 1) 3 132 2.3 BC026795
Rfc3 Rfc3 replication factor C (activator 1) 3 128 2.9 AK013095
Eif4a2 Rfc4 eukaryotic translation initiation factor 4A2 105 2.9 BB251459
Rfc4 Rfc4 replication factor C (activator 1) 4 188 3.0 BC003335
— Rfwd2 Mus musculus 9.5 days embryo 40 2.0 BB294853
parthenogenote cDNA, RIKEN full-length
enriched library, clone: B130031H03
product: unclassifiable, full insert
sequence
Rgs19 Rgs19 regulator of G-protein signaling 19 73 6.2 BB233670
Rgs2 Rgs2 regulator of G-protein signaling 2 425 2.0 AF215668
Rgs2 Rgs2 regulator of G-protein signaling 2 303 2.6 BB034265
Rgs2 Rgs2 regulator of G-protein signaling 2 454 2.6 AF215668
Arhb Rhob ras homolog gene family, member B 2877 2.9 BC018275
Arhg Rhog ras homolog gene family, member G 467 2.0 NM_019566
Arhh Rhoh ras homolog gene family, member H 67 5.0 BM243660
— Rims2 Mus musculus transcribed sequences 285 2.1 C79043
Ripk2 Ripk2 receptor (TNFRSF)-interacting serine- 225 2.0 NM_138952
threonine kinase 2
Ris2 Ris2 retroviral integration site 2 631 2.6 AF477481
Ris2 Ris2 retroviral integration site 2 228 2.0 AF477481
9530043P15Rik Rnase6 RIKEN cDNA 9530043P15 gene 66 6.5 AW825994
Rnaset2 Rnaset2; ribonuclease T2 154 2.2 AK015947
RNASE6PL;
0610007O07Rik;
4833423A10Rik;
4930532K22Rik
Trpc2 Rnf121 transient receptor potential cation 35 2.5 AW324327
channel, subfamily C, member 2
Rnpc2 Rnpc2 RNA-binding region (RNP1, RRM) 162 2.2 BB203348
containing 2
Rnpc2 Rnpc2 RNA-binding region (RNP1, RRM) 305 2.5 C79248
containing 2
Rnpc2 Rnpc2 RNA-binding region (RNP1, RRM) 233 2.3 C79248
containing 2
— Rnu22 Mus musculus 9 days embryo whole 352 2.3 BQ177137
body cDNA, RIKEN full-length enriched
library, clone: D030060F23 product: Mus
musculus U22 snoRNA host gene (UHG)
gene, complete sequence, full insert
sequence
— Rnu22 Mus musculus 9 days embryo whole 155 7.0 BB493265
body cDNA, RIKEN full-length enriched
library, clone: D030060F23 product: Mus
musculus U22 snoRNA host gene (UHG)
gene, complete sequence, full insert
sequence
Rp2h Rp2h retinitis pigmentosa 2 homolog (human) 185 2.3 BB431808
Rp2h Rp2h retinitis pigmentosa 2 homolog (human) 672 2.4 BB431808
Rpa2 Rpa2 replication protein A2 238 2.5 BC004578
Rpa2 Rpa2; Rf-A2 replication protein A2 208 2.2 AK011530
Rpgrip1 Rpgrip1 retinitis pigmentosa GTPase regulator 45 35.9 NM_023879
interacting protein 1
Rpl12 Rpl12 ribosomal protein L12 82 3.2 BG807990
Rps25 Rps25 ribosomal protein S25 250 2.1 BM729504
3010033P07Rik Rps9 RIKEN cDNA 3010033P07 gene 188 16.9 AA762498
Rrad Rrad Ras-related associated with diabetes 33 6.6 NM_019662
Rrm1 Rrm1 ribonucleotide reductase M1 383 3.3 BB758819
Rrm1 Rrm1 ribonucleotide reductase M1 380 3.3 BB758819
2510004L01Rik Rsad2 RIKEN cDNA 2510004L01 gene 1215 2.5 BB132493
— Rtn4 Mus musculus 16 days embryo head 158 3.4 BB648600
cDNA, RIKEN full-length enriched library,
clone: C130026I10 product: unknown
EST, full insert sequence
— Rtn4 Mus musculus 16 days embryo head 109 2.9 BG072267
cDNA, RIKEN full-length enriched library,
clone: C130026I10 product: unknown
EST, full insert sequence
Runx3 Runx3 runt related transcription factor 3 19 9.3 AV233043
S100a10 S100a10 S100 calcium binding protein A10 103 1.9 BB450829
(calpactin)
S100a4 S100a4 S100 calcium binding protein A4 120 13.7 D00208
S100a6 S100a6 S100 calcium binding protein A6 1217 2.8 NM_011313
(calcyclin)
S100a8 S100a8 S100 calcium binding protein A8 24 9.4 NM_013650
(calgranulin A)
S100a9 S100a9 S100 calcium binding protein A9 29 8.9 NM_009114
(calgranulin B)
Saa1 Saa1 serum amyloid A 1 18 20.0 NM_009117
Saa2 Saa2 serum amyloid A 2 33 3.0 NM_011314
Saa2 Saa2 serum amyloid A 2 62 7.0 NM_011314
Saa3 Saa3 serum amyloid A 3 110 8.6 NM_011315
Samhd1 Samhd1 SAM domain and HD domain, 1 418 11.3 NM_018851
Samhd1 Samhd1 SAM domain and HD domain, 1 185 11.4 BF148012
Samhd1 Samhd1 SAM domain and HD domain, 1 8 16.3 AV376100
Samsn1 Samsn1 SAM domain, SH3 domain and nuclear 49 9.1 NM_023380
localisation signals, 1
B130024B19Rik Sart2 RIKEN cDNA B130024B19 gene 62 5.7 BM207218
Satb1 Satb1 special AT-rich sequence binding protein 1 52 5.0 AV172776
Satb1 Satb1 special AT-rich sequence binding protein 1 68 2.9 AV172776
Scarb2 Scarb2 scavenger receptor class B, member 2 783 2.0 NM_007644
Sdc1 Sdc1 syndecan 1 337 2.9 BB533095
Sdccag8 Sdccag8 serologically defined colon cancer 114 3.5 BG695418
antigen 8
— Sec8l1 Mus musculus transcribed sequence with 59 2.3 BM941583
strong similarity to protein sp: P00722 (E. coli)
BGAL_ECOLI Beta-galactosidase
(Lactase)
Sectm1 Sectm1 secreted and transmembrane 1 516 2.9 AI481997
Sectm1 Sectm1 secreted and transmembrane 1 3261 3.0 AI481997
Sell Sell selectin, lymphocyte 69 14.0 M36005
Sell Sell selectin, lymphocyte 86 9.7 M36005
E330036L07Rik Senp1 RIKEN cDNA E330036L07 gene 75 2.2 BC023129
Sepw1 Sepw1 selenoprotein W, muscle 1 1468 2.0 BB464434
Serpina10 Serpina10 serine (or cysteine) proteinase inhibitor, 211 44.0 BC018416
clade A (alpha-1 antiproteinase,
antitrypsin), member 10
Serpina1a Serpina1a serine (or cysteine) proteinase inhibitor, 156 6.4 NM_009243
clade A, member 1a
Serpina1b Serpina1b serine (or cysteine) proteinase inhibitor, 2182 2.0 NM_009244
clade A, member 1b
Serpina3g Serpina3g serine (or cysteine) proteinase inhibitor, 92 107.8 BC002065
clade A, member 3G
Serpina3n Serpina3n serine (or cysteine) proteinase inhibitor, 18 10.9 NM_009252
clade A, member 3N
Serpinb1a Serpinb1a serine (or cysteine) proteinase inhibitor, 78 2.7 AF426024
clade B, member 1a
Serpinb1a Serpinb1a serine (or cysteine) proteinase inhibitor, 256 3.2 AF426024
clade B, member 1a
Serpinb6a Serpinb6a serine (or cysteine) proteinase inhibitor, 679 2.3 NM_009254
clade B, member 6a
Serpinb6b Serpinb6b serine (or cysteine) proteinase inhibitor, 375 4.2 NM_011454
clade B, member 6b
Serpinb9 Serpinb9 serine (or cysteine) proteinase inhibitor, 972 6.3 NM_009256
clade B, member 9
Serpinb9 Serpinb9 serine (or cysteine) proteinase inhibitor, 323 5.3 BE686716
clade B, member 9
Serpine1 Serpine1 serine (or cysteine) proteinase inhibitor, 80 4.3 NM_008871
clade E, member 1
Serping1 Serping1 serine (or cysteine) proteinase inhibitor, 2372 5.4 NM_009776
clade G, member 1
— Sertad4 Mus musculus 16 days embryo head 96 5.2 BQ174721
cDNA, RIKEN full-length enriched library,
clone: C130018M11
product: unclassifiable, full insert
sequence
Sfpi1 Sfpi1 SFFV proviral integration 1 116 5.5 NM_011355
Sfrs3 Sfrs3 splicing factor, arginine/serine-rich 3 1401 2.2 BB492363
(SRp20)
Sfrs7 Sfrs7 splicing factor, arginine/serine-rich 7 1701 2.1 BC027391
3300001M08Rik Sgol1 RIKEN cDNA 3300001M08 gene 16 3.9 BB410537
Sh3bgrl Sh3bgrl SH3-binding domain glutamic acid-rich 1195 2.0 AK004519
protein like
Sh3bgrl Sh3bgrl SH3-binding domain glutamic acid-rich 14 4.7 BB548587
protein like
Sh3bgrl3 Sh3bgrl3 SH3 domain binding glutamic acid-rich 1255 4.7 NM_080559
protein-like 3
Sh3bp2 Sh3bp2 SH3-domain binding protein 2 296 2.3 BC010198
Sh3kbp1 Sh3kbp1 SH3-domain kinase binding protein 1 18 3.8 BB766215
Sh3kbp1 Sh3kbp1 SH3-domain kinase binding protein 1 161 6.3 BB326929
Shcbp1 Shcbp1 Shc SH2-domain binding protein 1 35 12.4 NM_011369
— Siat4c — 32 3.4 BE954474
Siat8d Siat8d sialyltransferase 8 (alpha-2,8- 166 4.6 NM_009183
sialyltransferase) D
Sil Sil Tal1 interrupting locus 30 3.0 BC004585
Sit Sit SHP2 interacting transmembrane adaptor 57 2.2 NM_019436
Slamf1 Slamf1 signaling lymphocytic activation molecule 72 3.0 BB132695
family member 1
Slamf1 Slamf1 signaling lymphocytic activation molecule 12 7.9 BB132695
family member 1
Slamf7 Slamf7 SLAM family member 7 58 5.4 AK016183
Slamf8 Slamf8 SLAM family member 8 27 65.9 BC024587
Slamf9 Slamf9 SLAM family member 9 135 5.9 NM_029612
Slbp Slbp stem-loop binding protein 1160 2.3 NM_009193
Slc11a1 Slc11a1 solute carrier family 11 (proton-coupled 177 6.5 NM_013612
divalent metal ion transporters), member 1
Slc15a3 Slc15a3 solute carrier family 15, member 3 38 24.8 NM_023044
Slc20a1 Slc20a1 solute carrier family 20, member 1 890 2.6 NM_015747
2610016M12Rik Slc25a24 RIKEN cDNA 2610016M12 gene 93 3.1 BF578055
2610016M12Rik Slc25a24 RIKEN cDNA 2610016M12 gene 261 4.6 BM230959
Slc28a2 Slc28a2 solute carrier family 28 (sodium-coupled 9 21.0 NM_021520
nucleoside transporter), member 2
Slc2a3 Slc2a3 solute carrier family 2 (facilitated glucose 68 4.2 BB414515
transporter), member 3
Slc2a6 Slc2a6 solute carrier family 2 (facilitated glucose 14 15.4 BB196807
transporter), member 6
Slc31a2 Slc31a2 solute carrier family 31, member 2 350 2.5 NM_025286
Tramd1 Slc36a2 tramdorin 1 (transmembrane domain rich 26 3.3 AI596194
protein)
Slc38a1 Slc38a1 solute carrier family 38, member 1 193 2.4 NM_134086
Slc38a1 Slc38a1 solute carrier family 38, member 1 35 18.6 BF165681
F730005G13 Slc39a2 hypothetical protein F730005G13 23 5.0 BB049001
Slc39a6 Slc39a6 solute carrier family 39 (metal ion 375 2.4 BB825002
transporter), member 6
A230035L05Rik Slc41a2 RIKEN cDNA A230035L05 gene 765 2.3 BC026874
Eeg1 Slc43a3 embryonic epithelial gene 1 452 2.2 NM_021398
Slc4a7 Slc4a7 solute carrier family 4, sodium 81 2.2 BB454531
bicarbonate cotransporter, member 7
— Slc7a1 Mus musculus 7 days neonate 215 2.7 BB264620
cerebellum cDNA, RIKEN full-length
enriched library, clone: A730046J11
product: unclassifiable, full insert
sequence
— Slc7a1 Mus musculus 7 days neonate 331 2.7 BB264620
cerebellum cDNA, RIKEN full-length
enriched library, clone: A730046J11
product: unclassifiable, full insert
sequence
Slfn2 Slfn2 schlafen 2 190 12.0 NM_011408
Slfn8 Slfn8 schlafen 8 72 8.6 BC024709
Smc2l1 Smc2l1 SMC2 structural maintenance of 16 2.1 BI684556
chromosomes 2-like 1 (yeast)
Smc2l1 Smc2l1 SMC2 structural maintenance of 25 3.4 BI684556
chromosomes 2-like 1 (yeast)
Smc2l1 Smc2l1 SMC2 structural maintenance of 243 5.2 NM_008017
chromosomes 2-like 1 (yeast)
Smc4l1 Smc4l1 SMC4 structural maintenance of 699 3.3 AV172948
chromosomes 4-like 1 (yeast)
— Smc4l1 Mus musculus transcribed sequence with 56 6.7 BM244144
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
Smc4l1 Smc4l1 SMC4 structural maintenance of 196 4.0 BI665568
chromosomes 4-like 1 (yeast)
Smc4l1 Smc4l1 SMC4 structural maintenance of 243 5.3 BI665568
chromosomes 4-like 1 (yeast)
1110054A24Rik Smpdl3b RIKEN cDNA 1110054A24 gene 108 10.0 NM_133888
Snrpa1 Snrpa1 small nuclear ribonucleoprotein 790 2.1 BC013777
polypeptide A′
Snrpb2 Snrpb2 U2 small nuclear ribonucleoprotein B 906 2.2 AW537796
Snrpb2 Snrpb2 U2 small nuclear ribonucleoprotein B 1003 2.4 AV066554
Snx10 Snx10 sorting nexin 10 203 20.8 AK010399
2410003C09Rik Soat1 RIKEN cDNA 2410003C09 gene 197 3.1 BC025091
— Socs2 — 75 3.3 BB022048
Socs2 Socs2 suppressor of cytokine signaling 2 478 5.8 NM_007706
Socs2 Socs2 suppressor of cytokine signaling 2 354 5.5 NM_007706
Socs3 Socs3 suppressor of cytokine signaling 3 60 17.5 NM_007707
Socs3 Socs3 suppressor of cytokine signaling 3 153 22.3 BB241535
Socs3 Socs3 suppressor of cytokine signaling 3 98 17.8 BB831725
Solt Solt SoxLZ/Sox6 leucine zipper binding 95 3.8 NM_021790
protein in testis
— Spata5 Mus musculus transcribed sequences 30 2.9 BG069359
Spata5 Spata5 spermatogenesis associated 5 180 2.4 NM_021343
— Spata5 Mus musculus transcribed sequences 74 2.0 BG074352
Spata5 Spata5 spermatogenesis associated 5 32 5.6 BB819052
Sphk1 Sphk1 sphingosine kinase 1 171 2.1 AF068749
Spib Spib Spi-B transcription factor (Spi-1/PU.1 78 2.4 BM244106
related)
Spn Spn sialophorin 130 2.3 NM_009259
Spop Spop speckle-type POZ protein 45 2.6 AA688828
Spred1 Spred1 sprouty protein with EVH-1 domain 1, 890 2.0 BQ044290
related sequence
Ssb Ssb Sjogren syndrome antigen B 427 2.0 BG796845
Ssbp2 Ssbp2 single-stranded DNA binding protein 2 19 1.9 AK005150
BC030940 Ssh2 cDNA sequence BC030940 373 2.1 BB038915
0610038P07Rik Ssr3 RIKEN cDNA 0610038P07 gene 1890 2.7 AU022074
Stat1 Stat1 signal transducer and activator of 171 23.0 AW214029
transcription 1
— Stat1 Mus musculus transcribed sequences 85 19.6 BB229853
Stat1 Stat1 signal transducer and activator of 915 14.1 AW214029
transcription 1
Stat1 Stat1 signal transducer and activator of 808 22.7 AW214029
transcription 1
Stat2 Stat2 signal transducer and activator of 145 3.2 AF088862
transcription 2
Stat2 Stat2 signal transducer and activator of 138 6.1 AF088862
transcription 2
Stat3 Stat3 signal transducer and activator of 746 3.3 AK004083
transcription 3
Steap Steap six transmembrane epithelial antigen of 391 2.8 AF297098
the prostate
Steap Steap six transmembrane epithelial antigen of 176 3.9 AF297098
the prostate
Stk17b Stk17b serine/threonine kinase 17b (apoptosis- 240 9.3 AV173139
inducing)
Stk17b Stk17b serine/threonine kinase 17b (apoptosis- 364 9.3 AV173139
inducing)
Stk17b Stk17b serine/threonine kinase 17b (apoptosis- 70 4.9 AI661948
inducing)
Epb7.2 Stom erythrocyte protein band 7.2 83 2.4 AF093620
Strm Strm striamin 713 3.2 BE853286
Stx11 Stx11 syntaxin 11 59 10.1 AK017897
Sulf1 Sulf1 sulfatase 1 24 3.3 BB751459
Sulf1 Sulf1 sulfatase 1 42 5.3 BB065799
Suv39h1 Suv39h1 suppressor of variegation 3-9 homolog 1 184 3.3 AF193862
(Drosophila)
Suv39h2 Suv39h2 suppressor of variegation 3-9 homolog 2 29 3.1 NM_022724
(Drosophila)
Syk Syk spleen tyrosine kinase 39 2.7 U36776
Syk Syk spleen tyrosine kinase 98 3.4 AW907526
Syk Syk spleen tyrosine kinase 20 11.5 AW907526
Syncrip Syncrip synaptotagmin binding, cytoplasmic RNA 303 2.1 BG920261
interacting protein
Syt1 Syt1 synaptotagmin 1 64 2.1 BM118245
Syt13 Syt13 synaptotagmin 13 37 3.3 BB244585
T2bp T2bp Traf2 binding protein 317 3.7 BB277065
Tacc3 Tacc3 transforming, acidic coiled-coil containing 47 3.8 BB787809
protein 3
Tank Tank TRAF family member-associated Nf- 23 5.5 BB040938
kappa B activator
Tap2 Tap2 transporter 2, ATP-binding cassette, sub- 389 11.2 BE691515
family B (MDR/TAP)
Tapbp Tapbp TAP binding protein 917 4.6 AF043943
Tapbp Tapbp TAP binding protein 2304 5.5 AF043943
LOC213233 Tapbpl similar to hypothetical protein FLJ10143 255 7.4 BC017613
LOC213233 Tapbpl similar to hypothetical protein FLJ10143 36 5.3 BC017613
Tbc1d8 Tbc1d8 TBC1 domain family, member 8 135 2.2 BC005421
Tbk1 Tbk1 TANK-binding kinase 1 546 2.1 NM_019786
Tbx21 Tbx21 T-box 21 19 12.6 NM_019507
Tcerg1 Tcerg1 transcription elongation regulator 1 29 3.7 AW046403
(CA150)
Tcf7 Tcf7 transcription factor 7, T-cell specific 58 13.5 AI323642
— TCR beta-chain M. musculus mRNA for Tcell receptor, V-J 22 8.2 M87849
beta junctional region (clone T1CRP8)
— Tcra Mus musculus adult male thymus cDNA, 54 2.9 AV312643
RIKEN full-length enriched library,
clone: 5830404G23 product: T-cell
receptor alpha chain precursor V-J region
(TA72) (fragment) homolog [Mus
musculus], full insert sequence
— Tcra Mus musculus adult male thymus cDNA, 567 8.8 U95921
RIKEN full-length enriched library,
clone: 5830404G23 product: T-cell
receptor alpha chain precursor V-J region
(TA72) (fragment) homolog [Mus
musculus], full insert sequence
— Tcra Mus musculus adult male thymus cDNA, 697 7.7 U07662
RIKEN full-length enriched library,
clone: 5830404G23 product: T-cell
receptor alpha chain precursor V-J region
(TA72) (fragment) homolog [Mus
musculus], full insert sequence
— Tcra Mus musculus T cell receptor alpha chain 612 9.2 X01134
variable region (TCRAV3S9) mRNA,
partial cds
— Tcra Mus musculus adult male thymus cDNA, 27 7.5 BM243643
RIKEN full-length enriched library,
clone: 5830404G23 product: T-cell
receptor alpha chain precursor V-J region
(TA72) (fragment) homolog [Mus
musculus], full insert sequence
— Tcrb-J; — 31 3.1 AK018014
5830405F06Rik
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 21 4.0 U63547
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 68 55.0 U07661
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 22 7.0 AI021643
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 41 75.1 X67128
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 16 4.2 BF318536
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 28 7.5 M31648
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 217 28.7 U46841
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 12 6.8 U46841
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 17 24.4 X14388
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 65 55.9 M11456
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 13 170 29.2 M16120
Tes Tes testis derived transcript 400 2.8 BC010465
Tfdp1 Tfdp1 transcription factor Dp 1 709 2.1 BG075396
Tgfb1i1 Tgfb1i1 transforming growth factor beta 1 induced 268 2.0 NM_009365
transcript 1
Tgfbi Tgfbi transforming growth factor, beta induced 294 24.1 NM_009369
— Tgfbi — 219 27.0 BB533460
Tgfbi Tgfbi transforming growth factor, beta induced 229 19.6 NM_009369
Tgfbi Tgfbi transforming growth factor, beta induced 556 6.1 BB532080
— Tgfbr2 Mus musculus transcribed sequences 105 2.4 BB465968
5730599O09Rik Tgif2 RIKEN cDNA 5730599O09 gene 93 2.4 AW556273
Tgm2 Tgm2 transglutaminase 2, C polypeptide 4344 2.1 BB550124
Tgm2 Tgm2 transglutaminase 2, C polypeptide 3210 2.7 BB041811
— Tgn Mus musculus transcribed sequences 16 5.8 AI451480
Tgtp Tgtp T-cell specific GTPase 1220 24.4 NM_011579
Thbs1 Thbs1 thrombospondin 1 337 2.8 AI385532
Thbs1 Thbs1 thrombospondin 1 727 2.7 AI385532
Thbs2 Thbs2 thrombospondin 2 74 2.2 NM_011581
— Thrap2 Mus musculus transcribed sequences 18 4.5 C79489
Thy1 Thy1 thymus cell antigen 1, theta 53 28.3 AV028402
Timeless Timeless timeless homolog (Drosophila) 43 3.1 BM230269
Timeless Timeless timeless homolog (Drosophila) 117 3.4 BM230269
Timp1 Timp1 tissue inhibitor of metalloproteinase 1 69 61.5 BC008107
1110005A05Rik Tipin RIKEN cDNA 1110005A05 gene 507 2.3 AK011357
Tle4 Tle4 transducin-like enhancer of split 4, E(spl) 208 2.1 AU045006
homolog (Drosophila)
Tlr1 Tlr1 toll-like receptor 1 40 12.4 AF316985
Tlr2 Tlr2 toll-like receptor 2 145 11.9 NM_011905
Tlr3 Tlr3 toll-like receptor 3 252 2.3 NM_126166
Tlr3 Tlr3 toll-like receptor 3 129 3.9 NM_126166
Tlr4 Tlr4 toll-like receptor 4 19 3.1 BB148728
Tlr4 Tlr4 toll-like receptor 4 152 2.3 AF185285
Tlr4 Tlr4 toll-like receptor 4 91 2.2 AF185285
Tlr6 Tlr6 toll-like receptor 6 48 5.4 NM_011604
Tlr7 Tlr7 toll-like receptor 7 16 9.1 AY035889
Tm4sf7 Tm4sf7 transmembrane 4 superfamily member 7 1349 2.0 NM_053082
Tm6sf1 Tm6sf1 transmembrane 6 superfamily member 1 116 5.3 AV378394
Tm6sf1 Tm6sf1 transmembrane 6 superfamily member 1 280 2.8 AV378394
Mtf2 Tmed5 metal response element binding 283 2.0 BG066919
transcription factor 2
Tmod3 Tmod3 tropomodulin 3 447 2.1 BB224629
Tmod3 Tmod3 tropomodulin 3 452 2.1 AK017725
Tmpo Tmpo thymopoietin 1030 2.5 AA153892
Tmprss4 Tmprss4 transmembrane protease, serine 4 36 11.7 BC021368
— Tmsb10 M. musculus mRNA for testis-specific 4515 5.7 AV148480
thymosin beta-10
Tmsb10 Tmsb10 thymosin, beta 10 941 10.4 NM_025284
— Tmsb10 M. musculus mRNA for testis-specific 1945 7.8 BB096368
thymosin beta-10
Tmsb4x Tmsb4x thymosin, beta 4, X chromosome 9065 2.7 NM_021278
Tnfaip2 Tnfaip2 tumor necrosis factor, alpha-induced 749 1.9 NM_009396
protein 2
Tnfaip3 Tnfaip3 tumor necrosis factor, alpha-induced 77 4.8 NM_009397
protein 3
Tnfaip3 Tnfaip3 tumor necrosis factor, alpha-induced 236 4.3 BM241351
protein 3
Abcb1a Tnfaip9 ATP-binding cassette, sub-family B 95 5.7 NM_054098
(MDR/TAP), member 1A
Tnfrsf11b Tnfrsf11b tumor necrosis factor receptor 3 4.0 AB013898
superfamily, member 11b
(osteoprotegerin)
Tnfrsf12a Tnfrsf12a tumor necrosis factor receptor 810 2.5 NM_013749
superfamily, member 12a
Tnfrsf12a Tnfrsf12a tumor necrosis factor receptor 693 3.0 NM_013749
superfamily, member 12a
Tnfrsf14 Tnfrsf14 tumor necrosis factor receptor 14 10.0 BC022125
superfamily, member 14 (herpesvirus
entry mediator)
Tnfrsf18 Tnfrsf18 tumor necrosis factor receptor 81 5.5 AF229434
superfamily, member 18
Tnfrsf1b Tnfrsf1b tumor necrosis factor receptor 182 3.2 M60469
superfamily, member 1b
Tnfrsf4 Tnfrsf4 tumor necrosis factor receptor 163 4.7 NM_011659
superfamily, member 4
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 46 18.8 NM_011611
superfamily, member 5
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 48 20.4 BB220422
superfamily, member 5
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 95 15.7 AI385482
superfamily, member 5
Tnfrsf7 Tnfrsf7 tumor necrosis factor receptor 20 9.6 L24495
superfamily, member 7
Tnfsf10 Tnfsf10 tumor necrosis factor (ligand) 293 5.1 NM_009425
superfamily, member 10
Tnfsf13b Tnfsf13b tumor necrosis factor (ligand) 48 3.0 BB079466
superfamily, member 13b
Tnfsf13b Tnfsf13b tumor necrosis factor (ligand) 101 7.4 NM_033622
superfamily, member 13b
Tnfsf9 Tnfsf9 tumor necrosis factor (ligand) 29 5.3 NM_009404
superfamily, member 9
Tnip1 Tnip1 TNFAIP3 interacting protein 1 724 2.4 AJ242777
Top2a Top2a topoisomerase (DNA) II alpha 39 3.9 BB749838
Top2a Top2a topoisomerase (DNA) II alpha 142 14.7 BM211413
2810429C13Rik Topbp1 RIKEN cDNA 2810429C13 gene 334 2.5 BC007170
Tor3a Tor3a torsin family 3, member A 226 2.4 NM_023141
Tor3a Tor3a torsin family 3, member A 180 4.1 AK009693
Tor3a Tor3a torsin family 3, member A 287 3.3 NM_023141
— Tox Mus musculus transcribed sequences 24 4.1 BM124834
Tox Tox thymocyte selection-associated HMG box 6 10.5 BB547854
gene
Tox Tox thymocyte selection-associated HMG box 89 4.7 BB547854
gene
5430425C04Rik Tp53i5 RIKEN cDNA 5430425C04 gene 44 3.5 AK017334
Tpm2 Tpm2 tropomyosin 2, beta 307 2.5 BC024358
Tpm2 Tpm2 tropomyosin 2, beta 977 2.2 AK003186
— Tpm4 Mus musculus 7 days embryo whole 1905 2.9 AV122663
body cDNA, RIKEN full-length enriched
library, clone: C430002D13
product: TROPOMYOSIN 4 homolog
[Homo sapiens], full insert sequence
Tpst1 Tpst1 protein-tyrosine sulfotransferase 1 130 4.8 NM_013837
Tpt1h Tpt1h tRNA splicing 2′ phosphotransferase 1 181 16.0 BB113173
homolog (S. cerevisiae)
2610005B21Rik Tpx2 RIKEN cDNA 2610005B21 gene 132 3.4 AK011311
2610005B21Rik Tpx2 RIKEN cDNA 2610005B21 gene 9 6.5 AK011311
Traf1 Traf1 Tnf receptor-associated factor 1 40 6.1 BB218245
Traf1 Traf1 Tnf receptor-associated factor 1 34 10.8 BG064103
Trem3 Trem3 triggering receptor expressed on myeloid 96 2.4 NM_021407
cells 3
5031403H21Rik Treml4 RIKEN cDNA 5031403H21 gene 5 14.6 BB740529
— Trex1 Mus musculus adult female vagina 26 6.3 AF140709
cDNA, RIKEN full-length enriched library,
clone: 9930022F21 product: similar to G
PROTEIN COUPLED RECEPTOR [Mus
musculus], full insert sequence
Ifld2 Trib3 induced in fatty liver dystrophy 2 34 6.6 BB508622
Trim12 Trim12 tripartite motif protein 12 13 8.3 BM244351
Trim21 Trim21 tripartite motif protein 21 341 2.3 BC010580
Trim21 Trim21 tripartite motif protein 21 325 3.9 BC010580
Trim27 Trim27 tripartite motif protein 27 783 2.2 BB290427
Trim30 Trim30 tripartite motif protein 30 215 7.9 AF220015
Trim30 Trim30 tripartite motif protein 30 252 9.4 BM240719
9230105E10Rik Trim34 RIKEN cDNA 9230105E10 gene 427 4.5 BI653857
Trip13 Trip13 thyroid hormone receptor interactor 13 31 4.5 AK010336
Trip13 Trip13 thyroid hormone receptor interactor 13 56 9.0 AK010336
Tslpr Tslpr thymic stromal-derived lymphopoietin, 313 3.7 NM_016715
receptor
Ttk Ttk Ttk protein kinase 30 7.1 NM_009445
Tuba1 Tuba1 tubulin, alpha 1 1848 3.7 NM_011653
Tuba2 Tuba2 tubulin, alpha 2 9060 2.2 BC008117
Tuba8 Tuba8 tubulin, alpha 8 67 2.9 BB047533
Tubb2 Tubb2 tubulin, beta 2 969 2.9 BC003475
Tubb5 Tubb5 tubulin, beta 5 568 3.6 BG064086
Tubb5 Tubb5 tubulin, beta 5 2009 3.3 NM_011655
2310057H16Rik Tubb6 RIKEN cDNA 2310057H16 gene 204 4.2 NM_026473
Tube1 Tube1 epsilon-tubulin 1 27 2.7 AK010005
Txk Txk TXK tyrosine kinase 31 4.2 U19607
Tyki Tyki thymidylate kinase family LPS-inducible 406 3.0 AK004595
member
Tyrobp Tyrobp TYRO protein tyrosine kinase binding 261 17.8 NM_011662
protein
C330001M22 Ubash3a hypothetical protein C330001M22 89 3.1 BB397001
Ubd Ubd ubiquitin D 121 223.5 NM_023137
Ube2c Ube2c ubiquitin-conjugating enzyme E2C 133 10.5 AV162459
Ubce8 Ube2l6 ubiquitin-conjugating enzyme 8 85 8.7 BC008238
Ugcg Ugcg UDP-glucose ceramide 203 2.2 BF682223
glucosyltransferase
Ugcg Ugcg UDP-glucose ceramide 229 2.5 AA591863
glucosyltransferase
Np95 Uhrf1 nuclear protein 95 60 12.5 BB702754
Np95 Uhrf1 nuclear protein 95 43 6.5 BB702754
2510009H09Rik Unc5cl RIKEN cDNA 2510009H09 gene 71 2.5 AK010945
Unc93b Unc93b1 unc-93 homolog B (C. elegans) 424 3.3 BC018388
Upp1 Upp1 uridine phosphorylase 1 391 8.2 NM_009477
Usp18 Usp18 ubiquitin specific protease 18 165 20.6 NM_011909
— Usp32 Mus musculus transcribed sequence with 34 2.1 BB740339
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
Vasp Vasp vasodilator-stimulated phosphoprotein 705 3.1 BC015289
— Vcam1 Mus musculus transcribed sequences 49 20.6 AV280637
Vcam1 Vcam1 vascular cell adhesion molecule 1 152 25.4 L08431
1300011C24Rik Vdp RIKEN cDNA 1300011C24 gene 3412 2.0 AV139821
Vim Vim vimentin 1185 8.9 AV147875
Vim Vim vimentin 1376 8.7 M24849
Vim Vim vimentin 570 10.5 AV147875
Vps54 Vps54 vacuolar protein sorting 54 (yeast) 8 2.9 BB201271
Vrk1 Vrk1 vaccinia related kinase 1 243 2.0 BC016676
Vrk2 Vrk2 vaccinia related kinase 2 87 3.3 BC013520
Vrk2 Vrk2 vaccinia related kinase 2 154 3.0 AK012664
Wars Wars tryptophanyl-tRNA synthetase 387 2.4 BC003450
Wars Wars tryptophanyl-tRNA synthetase 791 2.7 BB785450
Wars Wars tryptophanyl-tRNA synthetase 193 4.6 AK004541
Wars Wars tryptophanyl-tRNA synthetase 768 2.9 AI528863
Was Was Wiskott-Aldrich syndrome homolog 25 17.0 NM_009515
(human)
Waspip Waspip Wiskott-Aldrich syndrome protein 249 4.9 C76969
interacting protein
Waspip Waspip Wiskott-Aldrich syndrome protein 195 4.6 C76969
interacting protein
Wbp5 Wbp5 WW domain binding protein 5 3473 2.1 BC007478
— Wbscr1 Mus musculus transcribed sequences 43 2.5 BI499987
Wbscr5 Wbscr5 Williams-Beuren syndrome chromosome 67 5.7 AF257136
region 5 homolog (human)
D630024B06Rik Wdhd1 RIKEN cDNA D630024B06 gene 71 5.0 C77437
Whsc1 Whsc1 Wolf-Hirschhorn syndrome candidate 1 104 2.8 AK017992
(human)
Wisp1 Wisp1 WNT1 inducible signaling pathway 145 2.4 NM_018865
protein 1
2700038M07Rik Wsb1 RIKEN cDNA 2700038M07 gene 786 2.1 BC019601
Xcl1 Xcl1 chemokine (C motif) ligand 1 32 18.1 NM_008510
Xdh Xdh xanthine dehydrogenase 167 16.7 AV286265
Ywhah Ywhah tyrosine 3-monooxygenase/tryptophan 5- 2590 2.2 NM_011738
monooxygenase activation protein, eta
polypeptide
Zap70 Zap70 zeta-chain (TCR) associated protein 45 6.2 BB204558
kinase
Zbp1 Zbp1 Z-DNA binding protein 1 49 78.0 AK008179
Zbp1 Zbp1 Z-DNA binding protein 1 14 118.4 NM_021394
Zc3hav1 Zc3hav1 zinc finger CCCH type, antiviral 1 174 2.0 AK004770
Zc3hav1 Zc3hav1 zinc finger CCCH type, antiviral 1 465 4.0 BB757349
Zc3hdc1 Zc3hdc1 zinc finger CCCH type domain containing 1 462 6.7 BM227980
A430104C18Rik Zc3hdc7 RIKEN cDNA A430104C18 gene 193 2.4 AW556219
2410141K03Rik Zcchc10 RIKEN cDNA 2410141K03 gene 159 2.1 BC025078
— Zcchc6 Mus musculus transcribed sequences 113 2.1 BI695361
1110051N18Rik Zcwcc3 RIKEN cDNA 1110051N18 gene 343 3.5 AI452146
1110051N18Rik Zcwcc3 RIKEN cDNA 1110051N18 gene 224 3.2 BC026506
— Zfhx1b Mus musculus transcribed sequence with 65 2.3 BG061923
moderate similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
— Zfhx1b Mus musculus Corpos mRNA, 3′ 59 3.1 BM220939
untranslated region
— Zfhx1b Mus musculus transcribed sequences 65 2.3 BB488200
Zfhx1b Zfhx1b zinc finger homeobox 1b 226 2.4 NM_015753
Zfp118 Zfp118 Zinc finger protein 118 59 2.2 BB176857
Zfp313 Zfp313 zinc finger protein 313 1410 2.0 BB251247
3732412P20 Zfp455 hypothetical protein 3732412P20 37 3.6 AV172851
Zfp472 Zfp472 zinc finger protein 472 149 2.1 BC023090
Zfp52 Zfp52 zinc finger protein 52 68 2.7 BM225280
Zfp52 Zfp52 zinc finger protein 52 263 2.4 BM225280
Zfp118 Zfp53 Zinc finger protein 118 132 2.3 NM_013843
Znfn1a1 Zfpn1a1 zinc finger protein, subfamily 1A, 1 85 19.8 AV317621
(Ikaros)
— Zfpn1a1 Mus musculus, clone IMAGE: 1263252, 40 2.6 BM237812
mRNA
Znfn1a3 Zfpn1a3 zinc finger protein, subfamily 1A, 3 42 4.4 BB202216
(Aiolos)
Znfn1a3 Zfpn1a3 zinc finger protein, subfamily 1A, 3 34 21.1 BB151746
(Aiolos)
Zfr Zfr zinc finger RNA binding protein 54 2.5 BB214490
Zfr Zfr zinc finger RNA binding protein 71 2.6 BM119505
Zipro1 Zipro1 zinc finger proliferation 1 185 3.0 AI326272
B830022L21Rik Znrf1 RIKEN cDNA B830022L21 gene 190 2.4 BC006765
— Zswim6 Mus musculus transcribed sequences 116 2.0 AI427602
D10Ertd749e Zwint DNA segment, Chr 10, ERATO Doi 749, 143 2.6 BC013559
expressed
Brd7 bromodomain containing 7 14 2.4 BB022341
— Mus musculus transcribed sequence with 229 2.5 BG143461
strong similarity to protein sp: P00722 (E. coli)
BGAL_ECOLI Beta-galactosidase
(Lactase)
— Mus musculus transcribed sequences 24 2.9 BB066105
Crsp9 cofactor required for Sp1 transcriptional 59 2.2 AK009549
activation, subunit 9, 33 kDa
— — 104 2.6 BQ033755
— Mus musculus transcribed sequences 8 3.1 BE686253
— Mus musculus 0 day neonate eyeball 40 2.6 BB710625
cDNA, RIKEN full-length enriched library,
clone: E130307M10
product: unclassifiable, full insert
sequence
— Mus musculus transcribed sequence with 223 3.8 AW556821
weak similarity to protein pir: I58401
(M. musculus) I58401 protein-tyrosine
kinase (EC 2.7.1.112) JAK3 - mouse
— — 1919 3.2 AY052560
Srrm1 serine/arginine repetitive matrix 1 43 2.5 BB254130
— Mus musculus adult male aorta and vein 54 2.3 BB224338
cDNA, RIKEN full-length enriched library,
clone: A530086D01 product: unknown
EST, full insert sequence
— — 78 4.4 BB116018
— Mus musculus transcribed sequences 37 2.5 BE691393
— Mus musculus transcribed sequences 57 3.1 BE943672
— Mus musculus transcribed sequences 12 5.8 BE447255
Loxl2 lysyl oxidase-like 2 231 2.2 AI415741
— Mus musculus 16 days neonate heart 24 3.1 BB042982
cDNA, RIKEN full-length enriched library,
clone: D830032E20 product: similar to
ENVELOPE PROTEIN (FRAGMENT)
[Friend spleen focus-forming virus], full
insert sequence
Pfkp phosphofructokinase, platelet 438 2.3 BB076574
Itgb4bp integrin beta 4 binding protein 174 2.0 AK018313
— Mus musculus 2 days neonate thymus 102 3.3 BI076809
thymic cells cDNA, RIKEN full-length
enriched library, clone: E430008K23
product: unknown EST, full insert
sequence
— Mus musculus 12 days embryo 54 2.2 BM239026
embryonic body between diaphragm
region and neck cDNA, RIKEN full-length
enriched library, clone: 9430088I02
product: unknown EST, full insert
sequence
— Mus musculus adult male thymus cDNA, 5 8.8 BB241847
RIKEN full-length enriched library,
clone: 5830404C02 product: unknown
EST, full insert sequence
— — 12 2.2 BB800744
Cp ceruloplasmin 232 2.0 BB332449
— Mus musculus transcribed sequence with 55 3.5 BG075163
strong similarity to protein sp: Q9NZJ4
(H. sapiens) SACS_HUMAN Sacsin
Etv3 ets variant gene 3 284 2.5 BI456953
Strn3 striatin, calmodulin binding protein 3 114 2.0 BB228907
— Mus musculus 2 days pregnant adult 61 5.5 BE989616
female ovary cDNA, RIKEN full-length
enriched library, clone: E330027C07
product: weakly similar to ZINC FINGER
PROTEIN 43 (HTF6) [Homo sapiens], full
insert sequence
— Mus musculus 9 days embryo whole 69 4.3 BF163381
body cDNA, RIKEN full-length enriched
library, clone: D030060F23 product: Mus
musculus U22 snoRNA host gene (UHG)
gene, complete sequence, full insert
sequence
— Mus musculus transcribed sequences 32 2.6 AV300631
— — 104 2.7 AV084904
Zfp295 zinc finger protein 295 102 2.2 BB091040
— Mus musculus transcribed sequences 62 2.3 BB230267
H2afz H2A histone family, member Z 765 1.9 AV215230
— Mus musculus similar to FLJ14075 80 2.1 BG071110
protein (LOC217431), mRNA
— Mus musculus 0 day neonate skin cDNA, 47 2.3 AV233462
RIKEN full-length enriched library,
clone: 4632424N07 product: unknown
EST, full insert sequence
— Mus musculus adult male thymus cDNA, 55 2.8 AV312603
RIKEN full-length enriched library,
clone: 5830404C02 product: unknown
EST, full insert sequence
— Mus musculus transcribed sequences 134 2.8 BI466416
— Mus musculus transcribed sequence with 20 2.8 AI452166
weak similarity to protein
ref: NP_061226.1 (M. musculus) 2-cell-
stage, variable group, member 1; variable
group of 2-cell-stage gene family [Mus
musculus]
1700029I01Rik RIKEN cDNA 1700029I01 gene 81 3.5 AV047635
— Mus musculus transcribed sequences 62 5.9 AV247387
— Mus musculus cDNA clone MGC: 6071 130 3.3 BC022776
IMAGE: 3492410, complete cds
— — 68 4.0 BB256262
Smc6l1 SMC6 structural maintenance of 43 3.0 BB056038
chromosomes 6-like 1 (yeast)
— Mus musculus transcribed sequences 63 2.1 BB473548
— Mus musculus transcribed sequences 36 2.7 AU040162
— Mus musculus 0 day neonate eyeball 48 2.1 BB541236
cDNA, RIKEN full-length enriched library,
clone: E130112O04 product: unknown
EST, full insert sequence
— — 6 9.3 BB030365
— Mus musculus transcribed sequences 79 2.5 BG069527
— — 8 3.4 AI661342
— Mus musculus transcribed sequences 229 2.2 BM218086
2210023K21Rik RIKEN cDNA 2210023K21 gene 125 4.7 BI106821
— — 94 2.1 BG074662
Igsf6 immunoglobulin superfamily, member 6 23 2.8 AV078837
— Mus musculus transcribed sequence with 29 2.4 BB449580
weak similarity to protein pir: S12207
(M. musculus) S12207 hypothetical
protein (B2 element) - mouse
Rp2h retinitis pigmentosa 2 homolog (human) 209 2.2 BF168611
— Mus musculus transcribed sequences 37 3.9 BE634580
Stk4 serine/threonine kinase 4 1036 2.0 BB141897
Ccr7 chemokine (C-C motif) receptor 7 4 9.9 BB204380
— Mus musculus adult male thymus cDNA, 28 3.1 BB165850
RIKEN full-length enriched library,
clone: 5830443J22 product: unknown
EST, full insert sequence
— Mus musculus 0 day neonate eyeball 67 2.1 BB538708
cDNA, RIKEN full-length enriched library,
clone: E130013E11 product: unknown
EST, full insert sequence
— Mus musculus similar to Elongation factor 154 4.1 AV328340
1-alpha 1 (EF-1-alpha-1) (Elongation
factor 1 A-1) (eEF1A-1) (Elongation
factor Tu) (EF-Tu) (LOC381109), mRNA
2610018G03Rik RIKEN cDNA 2610018G03 gene 123 2.0 AW556821
— Mus musculus transcribed sequences 36 3.5 BB208080
— Mus musculus transcribed sequences 21 3.0 BB271581
Atf4 activating transcription factor 4 398 2.4 AV314773
— Mus musculus transcribed sequences 52 2.3 BB458874
2610039C10Rik RIKEN cDNA 2610039C10 gene 113 3.5 AK012762
— Mus musculus transcribed sequence with 42 2.1 AV372127
moderate similarity to protein
ref: NP_038602.1 (M. musculus) L1
repeat, Tf subfamily, member 18 [Mus
musculus]
— Mus musculus transcribed sequences 224 3.0 AA266723
— — 388 2.0 AV368189
E430036I04Rik RIKEN cDNA E430036I04 gene 85 6.8 BB329408
— — 98 2.4 BQ266693
Rp2h retinitis pigmentosa 2 homolog (human) 188 2.2 BF168611
— Mus musculus similar to DYSKERIN 190 4.4 BB779105
(LOC245474), mRNA
0610025L06Rik RIKEN cDNA 0610025L06 gene 1362 6.2 AV010467
— Mus musculus, clone IMAGE: 5066616, 72 3.7 BE373131
mRNA
— Mus musculus transcribed sequences 21 2.4 BM196689
— — 157 2.2 BG976607
— Mus musculus transcribed sequences 9 5.0 BB534560
C330006D17Rik RIKEN cDNA C330006D17 gene 191 2.4 BB397948
— — 169 4.7 BG976607
— Mus musculus transcribed sequence with 96 2.2 BB667685
weak similarity to protein pir: S12207
(M. musculus) S12207 hypothetical
protein (B2 element) - mouse
— Mus musculus transcribed sequences 53 12.1 BM246630
— Mus musculus transcribed sequence with 29 3.8 AI451538
weak similarity to protein pir: S12207
(M. musculus) S12207 hypothetical
protein (B2 element) - mouse
— — 299 2.3 BG976607
— Mus musculus mRNA similar to 33 5.1 BC020118
interferon-inducible GTPase (cDNA clone
MGC: 49532 IMAGE: 3495064), complete
cds
Mll myeloid/lymphoid or mixed-lineage 128 2.0 AK017541
leukemia
— Mus musculus transcribed sequences 46 2.5 BG073023
Cp ceruloplasmin 1596 3.9 BB332449
— Mus musculus similar to 2-cell-stage, 96 2.1 BG070246
variable group, member 3; 2-cell-stage,
variable group, member 1 (LOC236374),
mRNA
— — 28 5.3 BC003855
— Mus musculus similar to Ig delta chain C 29 3.5 BE686052
region, membrane-bound form - mouse
(LOC382646), mRNA
3010033P07Rik RIKEN cDNA 3010033P07 gene 114 2.5 AK013903
— Mus musculus transcribed sequences 94 3.6 BB376947
— Mus musculus transcribed sequences 182 2.8 BB829165
Pscdbp pleckstrin homology, Sec7 and coiled-coil 1081 3.1 BB503614
domains, binding protein
— — 1108 2.5 BB145101
Hmmr hyaluronan mediated motility receptor 82 3.0 X64550
(RHAMM)
— Mus musculus 0 day neonate thymus 25 3.8 AI840829
cDNA, RIKEN full-length enriched library,
clone: A430110E23 product: unknown
EST, full insert sequence
Nr4a2 nuclear receptor subfamily 4, group A, 23 2.8 BB703394
member 2
Rod1 ROD1 regulator of differentiation 1 (S. pombe) 130 3.4 BB519382
Eif4ebp1 eukaryotic translation initiation factor 4E 393 2.6 AV216412
binding protein 1
— Mus musculus transcribed sequences 94 2.5 BE634878
— Mus musculus adult male tongue cDNA, 19 3.3 BG061080
RIKEN full-length enriched library,
clone: 2310050P20 product: unknown
EST, full insert sequence
Col1a1 procollagen, type I, alpha 1 138 5.9 BI794771
— Mus musculus 18 days pregnant adult 136 2.4 BI082172
female placenta and extra embryonic
tissue cDNA, RIKEN full-length enriched
library, clone: 3830421G02
product: unknown EST, full insert
sequence
— — 512 2.9 BG976607
— — 244 3.7 BM941868
— — 1603 3.3 BF719154
Ncf1 neutrophil cytosolic factor 1 35 15.5 BE370703
— Mus musculus diabetic nephropathy- 118 58.3 BM241271
related gene 1 mRNA, partial sequence
— Mus musculus transcribed sequence with 148 6.7 BB160586
moderate similarity to protein pir: A39822
(H. sapiens) A39822 leukosialin precursor -
human
— Mus musculus transcribed sequences 125 3.9 BB667149
Rrm2 ribonucleotide reductase M2 412 8.2 AV301324
— Mus musculus transcribed sequences 96 2.4 BM243375
— — 138 2.1 BI155210
Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1234 2.5 AV111502
39
— — 17 4.6 AV340322
Cp ceruloplasmin 915 4.3 BB332449
— Mus musculus transcribed sequence with 91 3.0 BB281100
moderate similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
— — 230 5.3 U29539
Gna13 guanine nucleotide binding protein, alpha 1362 2.3 BI662324
13
— Mus musculus transcribed sequences 66 2.5 AA267568
— Mus musculus 16 days neonate heart 19 4.3 BB518323
cDNA, RIKEN full-length enriched library,
clone: D830028N22
product: unclassifiable, full insert
sequence
Rp2h retinitis pigmentosa 2 homolog (human) 202 2.2 BF168611
— Mus musculus adult male cecum cDNA, 28 4.8 AI506672
RIKEN full-length enriched library,
clone: 9130208D14 product: unknown
EST, full insert sequence
— Mus musculus transcribed sequences 96 3.3 BB767243
9930027N05Rik RIKEN cDNA 9930027N05 gene 41 39.3 AI662854
— Mus musculus transcribed sequence with 35 9.3 BB740904
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
— Mus musculus transcribed sequences 35 2.6 BM239760
— Mus musculus transcribed sequence with 68 2.9 BF714880
moderate similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
— Mus musculus transcribed sequences 110 3.5 BM222853
Cp ceruloplasmin 838 4.2 BB332449
Ncf1 neutrophil cytosolic factor 1 60 7.0 BE370703
— — 59 37.3 BE688410
Hn1 hematological and neurological 194 7.9 AV067695
expressed sequence 1
— — 986 20.1 AV066625
Myadm myeloid-associated differentiation marker 1120 2.1 BB500055
Vcam1 vascular cell adhesion molecule 1 296 19.2 BB250384
Cugbp2 CUG triplet repeat, RNA binding protein 2 148 6.0 BB667096
— Mus musculus 3 days neonate thymus 41 40.5 BB207611
cDNA, RIKEN full-length enriched library,
clone: A630020E03 product: unknown
EST, full insert sequence
— Mus musculus transcribed sequence with 510 2.3 AV216768
strong similarity to protein sp: Q61753
(M. musculus) SERA_MOUSE D-3-
phosphoglycerate dehydrogenase (3-
PGDH) (A10)
Cxcl9 chemokine (C—X—C motif) ligand 9 33 69.4 BI104444
Rod1 ROD1 regulator of differentiation 1 (S. pombe) 138 4.6 BB519382
— — 19 17.8 BC003855
— Mus musculus transcribed sequence with 536 3.9 C76675
strong similarity to protein sp: P10660
(H. sapiens) RS6_HUMAN 40S ribosomal
protein S6 (Phosphoprotein NP33)
— Mus musculus transcribed sequences 28 33.7 BB224524
— Mus musculus adult male aorta and vein 18 23.4 BE692425
cDNA, RIKEN full-length enriched library,
clone: A530049N04 product: unknown
EST, full insert sequence
— Mus musculus similar to toll-like receptor 32 15.8 BI655907
(LOC279572), mRNA
— Mus musculus transcribed sequences 196 3.2 AW543723
— — 31 17.1 BG072508
Etv3 ets variant gene 3 198 2.1 BI456953
— Mus musculus transcribed sequences 12 2.3 BF321297
— — 19 67.1 NM_022429
— Mus musculus similar to AIM2 protein 15 4.0 BE685969
(LOC383619), mRNA
Cnp1 cyclic nucleotide phosphodiesterase 1 354 6.3 BB251922
— — 286 2.9 BC004065
Tpm3 tropomyosin 3, gamma 621 3.8 AV311925
2210023K21Rik RIKEN cDNA 2210023K21 gene 381 5.8 BI106821
— Mus musculus transcribed sequences 115 61.7 AW111920
— — 172 12.6 BB668084
— — 24 7.8 AV247013
— — 38 29.1 BE688410
— Mus musculus transcribed sequence with 21 6.6 BB535821
weak similarity to protein
ref: NP_081764.1 (M. musculus) RIKEN
cDNA 5730493B19 [Mus musculus]
Rps3 ribosomal protein S3 138 2.0 BG069767
— Mus musculus adult male aorta and vein 6 5.5 BB214834
cDNA, RIKEN full-length enriched library,
clone: A530023D22
product: unclassifiable, full insert
sequence
— — 55 6.8 BB135602
— Mus musculus, clone IMAGE: 1348774, 11 28.8 AA666504
mRNA
Cnn3 calponin 3, acidic 943 4.2 BB490338
Hrasls3 HRAS like suppressor 3 372 21.7 BB404920
— Mus musculus similar to surface protein 17 7.5 BE629676
MCA-32 (LOC380732), mRNA
— Mouse non-productive mRNA for T-cell 6 23.2 NM_011558
receptor gamma V5-J1-C1
G1p2 interferon, alpha-inducible protein 112 16.7 AK019325
Pim1 proviral integration site 1 261 4.9 AI323550
Vcam1 vascular cell adhesion molecule 1 268 39.1 BB250384
1200008O12Rik RIKEN cDNA 1200008O12 gene 7 6.5 AV126179
— Mus musculus adult male cortex cDNA, 336 10.9 BB645745
RIKEN full-length enriched library,
clone: B530033B21 product: unknown
EST, full insert sequence
— Mus musculus transcribed sequences 12 7.8 BB552085
G1p2 interferon, alpha-inducible protein 17 10.3 AK019325
Nfkbia nuclear factor of kappa light chain gene 1311 4.1 BB096843
enhancer in B-cells inhibitor, alpha
TABLE 3
Transcripts decreased in GKO D5
WT D5 GKO
Gene Symbol vs D5 vs
Affymetrix Common Gene Title Affymetrix NCBA NCBA Genbank
BC027231 0610037H22Rik cDNA sequence BC027231 1.0 0.4 AU051504
0610037M15Rik 0610037M15Rik RIKEN cDNA 0610037M15 15.6 3.2 BG916808
gene
1110007F12Rik 1110007F12Rik RIKEN cDNA 1110007F12 3.0 0.6 BC020080
gene
1110013L07Rik 1110013L07Rik RIKEN cDNA 1110013L07 3.0 1.5 BB765852
gene
1110032F04Rik 1110032F04Rik RIKEN cDNA 1110032F04 1.3 0.4 BE985708
gene
1200015F23Rik 1200015F23Rik RIKEN cDNA 1200015F23 1.1 0.5 AK004786
gene
1200015F23Rik 1200015F23Rik RIKEN cDNA 1200015F23 1.8 0.6 AK004786
gene
1500004A08Rik 1500004A08Rik RIKEN cDNA 1500004A08 2.3 1.1 BB030508
gene
1700008D07Rik 1700008D07Rik RIKEN cDNA 1700008D07 0.9 0.4 AK005758
gene
1700012B18Rik 1700012B18Rik RIKEN cDNA 1700012B18 0.7 0.4 BC022135
gene
— 1700091G21Rik Mus musculus 16 days 4.3 2.1 BG075562
neonate thymus cDNA,
RIKEN full-length enriched
library, clone: A130042K22
product: unknown EST, full
insert sequence
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 5.4 1.9 BB397062
gene
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 4.5 2.1 BB259628
gene
1810054D07Rik 1810054D07Rik RIKEN cDNA 1810054D07 5.0 2.2 AK007856
gene
1810062O14Rik 1810062O14Rik RIKEN cDNA 1810062O14 7.4 3.5 AV060417
gene
— 2010001M06Rik Mus musculus adult male 0.9 0.3 BE200030
small intestine cDNA, RIKEN
full-length enriched library,
clone: 2010001M06
product: unknown EST, full
insert sequence
2210019E14Rik 2210019E14Rik RIKEN cDNA 2210019E14 1.5 0.8 BB771921
gene
2210421G13Rik 2210421G13Rik RIKEN cDNA 2210421G13 9.3 0.8 AV081797
gene
Elk4 2310011G17Rik ELK4, member of ETS 0.4 0.2 AW046689
oncogene family
2310047C04Rik 2310047C04Rik RIKEN cDNA 2310047C04 1.2 0.3 BM231657
gene
2600014C01Rik 2600014C01Rik RIKEN cDNA 2600014C01 0.6 0.2 BC027339
gene
2610042L04Rik 2610042L04Rik RIKEN cDNA 2610042L04 5.0 0.9 BM195235
gene
2610042L04Rik 2610042L04Rik RIKEN cDNA 2610042L04 4.9 0.9 BM195235
gene
2610305D13Rik 2610305D13Rik RIKEN cDNA 2610305D13 0.7 0.1 AK011986
gene
2610528J11Rik 2610528J11Rik RIKEN cDNA 2610528J11 0.3 0.1 AK012175
gene
2700007P21Rik 2700007P21Rik RIKEN cDNA 2700007P21 1.1 0.4 BB552785
gene
LOC217820 2700069A02Rik hypothetical protein 0.8 0.4 BM198642
LOC217820
2810022L02Rik 2810022L02Rik RIKEN cDNA 2810022L02 0.9 0.3 BC014764
gene
2810429K17Rik 2810429K17Rik RIKEN cDNA 2810429K17 0.7 0.2 AK013194
gene
2900024C23Rik 2900024C23Rik RIKEN cDNA 2900024C23 1.3 0.5 AK013580
gene
4631426E05Rik 4631426E05Rik RIKEN cDNA 4631426E05 0.2 0.1 BB739558
gene
— 4921504P05Rik — 0.8 0.4 AK014814
4930402H24Rik 4930402H24Rik RIKEN cDNA 4930402H24 1.1 0.4 AK015050
gene
4930413O22Rik 4930413O22Rik RIKEN cDNA 4930413O22 1.1 0.5 NM_026493
gene
— 4930420O11Rik Mus musculus 4 days 1.8 0.7 BB328498
neonate male adipose cDNA,
RIKEN full-length enriched
library, clone: B430318O09
product: CDNA FLJ33039 FIS,
CLONE THYMU2000369,
MODERATELY SIMILAR TO
MUS MUSCULUS
SYNTROPHIN-ASSOCIATED
SERINE-THREONINE
PROTEIN KINASE MRNA
homolog [. . .
4930422I07Rik 4930422I07Rik RIKEN cDNA 4930422I07 0.9 0.3 BG068263
gene
— 4930488P18Rik — 1.4 0.2 AV057155
4930562F07Rik 4930523C07Rik RIKEN cDNA 4930562F07 1.3 0.6 AV032877
gene
4930550C14Rik 4930550C14Rik RIKEN cDNA 4930550C14 1.9 0.6 AK016083
gene
— 4930556N09Rik Mus musculus adult male 1.3 0.5 AK016152
testis cDNA, RIKEN full-
length enriched library,
clone: 4930556N09
product: unclassifiable, full
insert sequence
1810010E01Rik 4930579G22Rik RIKEN cDNA 1810010E01 1.0 0.4 BI202437
gene
4933409L06Rik 4933409L06Rik RIKEN cDNA 4933409L06 1.3 0.6 BB645791
gene
— 4933412E12Rik Mus musculus 13 days 2.2 0.5 AK016788
embryo heart cDNA, RIKEN
full-length enriched library,
clone: D330011B05
product: unknown EST, full
insert sequence
— 4933412E12Rik — 1.5 0.4 BB265147
4933415L06Rik 4933415L06Rik RIKEN cDNA 4933415L06 1.0 0.4 AW554226
gene
— 4933417N07Rik Mus musculus adult male 1.1 0.6 AK016849
testis cDNA, RIKEN full-
length enriched library,
clone: 4933417N07
product: unknown EST, full
insert sequence
— 4933422E07Rik Mus musculus adult male 1.2 0.6 BE630630
bone cDNA, RIKEN full-length
enriched library,
clone: 9830114D01
product: hypothetical protein,
full insert sequence
5133401N09Rik 5133401N09Rik RIKEN cDNA 5133401N09 1.9 0.7 BC026742
gene
5830405N20Rik 5830405N20Rik RIKEN cDNA 5830405N20 2.5 0.8 BB202848
gene
9630005B12Rik 5830411O09Rik RIKEN cDNA 9630005B12 2.4 0.8 BB431654
gene
AI595338 5830443L24Rik expressed sequence 75.0 0.4 NM_029509
AI595338
5830458K16Rik 5830458K16Rik RIKEN cDNA 5830458K16 9.1 1.6 BC024872
gene
5830484A20Rik 5830484A20Rik RIKEN cDNA 5830484A20 1.2 0.5 BG072319
gene
5830484A20Rik 5830484A20Rik RIKEN cDNA 5830484A20 4.8 2.0 AW909306
gene
9130002C22Rik 9130002C22Rik RIKEN cDNA 9130002C22 24.4 6.4 BM243571
gene
9130019I15Rik 9130019I15Rik RIKEN cDNA 9130019I15 46.3 13.7 AK018636
gene
9130022K13Rik 9130022K13Rik RIKEN cDNA 9130022K13 5.6 1.3 AK018646
gene
— 9130430L19Rik Mus musculus adult male 1.5 0.7 AK020296
cecum cDNA, RIKEN full-
length enriched library,
clone: 9130430L19
product: unknown EST, full
insert sequence
9230105E10Rik 9230105E10Rik RIKEN cDNA 9230105E10 3.6 0.6 BB433710
gene
9330177P20Rik 9330177P20Rik RIKEN cDNA 9330177P20 1.3 0.6 BB375580
gene
— 9530028C05 Mus musculus adult male 3.9 1.7 BQ175154
testis cDNA, RIKEN full-
length enriched library,
clone: 4921508F21
product: similar to
HISTOCOMPATIBILITY 2,
CLASS II ANTIGEN E BETA
[Mus musculus], full insert
sequence
— 9530028C05 Mus musculus adult male 4.6 2.0 BQ175154
testis cDNA, RIKEN full-
length enriched library,
clone: 4921508F21
product: similar to
HISTOCOMPATIBILITY 2,
CLASS II ANTIGEN E BETA
[Mus musculus], full insert
sequence
A030012M09Rik A030012M09Rik RIKEN cDNA A030012M09 0.9 0.4 BB549335
gene
A130015N09Rik A130015N09Rik RIKEN cDNA A130015N09 0.5 0.2 AI647939
gene
— A330042I21Rik Mus musculus adult male 3.6 0.4 BB187486
spinal cord cDNA, RIKEN full-
length enriched library,
clone: A330042I21
product: unknown EST, full
insert sequence
— A330042I21Rik Mus musculus adult male 3.6 0.4 AI645293
spinal cord cDNA, RIKEN full-
length enriched library,
clone: A330042I21
product: unknown EST, full
insert sequence
A530088I07Rik A530088I07Rik RIKEN cDNA A530088I07 1.8 0.3 BB637972
gene
A630024B12Rik A630024B12Rik RIKEN cDNA A630024B12 1.2 0.3 BB240995
gene
A630077B13Rik A630077B13Rik RIKEN cDNA A630077B13 183.1 1.5 BB239429
gene
AA960558 AA960558 expressed sequence 1.4 0.7 BB277078
AA960558
Abca13 Abca13 ATP-binding cassette, sub- 0.9 0.2 BB503961
family A (ABC1), member 13
Abcc2 Abcc2 ATP-binding cassette, sub- 0.4 0.1 NM_013806
family C (CFTR/MRP),
member 2
Acas2 Acas2 acetyl-Coenzyme A 0.3 0.1 NM_019811
synthetase 2 (ADP forming)
Adamts15 Adamts15 a disintegrin-like and 0.3 0.1 AV228731
metalloprotease (reprolysin
type) with thrombospondin
type 1 motif, 15
Agtrap Agtrap angiotensin II, type I receptor- 0.8 0.2 NM_009642
associated protein
AI447904 AI447904 expressed sequence 70.3 9.7 BM241008
AI447904
AI447904 AI447904 expressed sequence 26.2 7.6 BM241008
AI447904
— AI451557 Mus musculus transcribed 24.1 3.1 AV277444
sequences
LOC226691 AI607873 interferon-activatable protein 28.9 9.7 AI607873
AI649392 AI649392 expressed sequence 0.9 0.4 BB496366
AI649392
AI788959 AI788959 expressed sequence 0.7 0.1 BC028826
AI788959
AI848100 AI848100 expressed sequence 0.9 0.4 BB148987
AI848100
Aif1 Aif1 allograft inflammatory factor 1 36.5 9.1 NM_019467
4930502N02Rik Ak7 RIKEN cDNA 4930502N02 2.5 0.4 AV256298
gene
Akr1c20 Akr1c20 aldo-keto reductase family 1, 8.0 2.0 BC021607
member C20
Akr1c21 Akr1c21 aldo-keto reductase family 1, 0.5 0.1 AW146041
member C21
Aldh1a1 Aldh1a1 aldehyde dehydrogenase 0.5 0.1 NM_013467
family 1, subfamily A1
Aldh1b1 Aldh1b1 aldehyde dehydrogenase 1 2.7 1.2 BC020001
family, member B1
Aldh8a1 Aldh8a1 aldehyde dehydrogenase 8 0.3 0.1 BC013511
family, member A1
2810455B10Rik Als2cr19 RIKEN cDNA 2810455B10 1.0 0.4 AK008055
gene
Amacr Amacr alpha-methylacyl-CoA 0.2 0.0 NM_008537
racemase
— Ankib1 Mus musculus 16 days 0.9 0.3 BB373816
embryo head cDNA, RIKEN
full-length enriched library,
clone: C130072C03
product: hypothetical protein,
full insert sequence
Apg12l Apg12l autophagy 12-like (S. cerevisiae) 0.9 0.4 AK016474
App App amyloid beta (A4) precursor 2.3 0.7 AV348729
protein
Arhgap15 Arhgap15 Rho GTPase activating 1.9 0.8 AK018058
protein 15
Arhgap18 Arhgap18 Rho GTPase activating 0.4 0.2 BE307291
protein 18
Arl2bp Arl2bp ADP-ribosylation factor-like 2 0.9 0.4 NM_024191
binding protein
1200015K23Rik Armc8 RIKEN cDNA 1200015K23 1.2 0.5 BE995635
gene
Arts1 Arts1 type 1 tumor necrosis factor 4.8 1.9 NM_030711
receptor shedding
aminopeptidase regulator
Arts1 Arts1 type 1 tumor necrosis factor 4.1 1.2 AV287655
receptor shedding
aminopeptidase regulator
Asb13 Asb13 ankyrin repeat and SOCS 0.8 0.4 AF403041
box-containing protein 13
Asb13 Asb13 ankyrin repeat and SOCS 0.9 0.4 AF403041
box-containing protein 13
A330005H02Rik Atp11c RIKEN cDNA A330005H02 0.7 0.2 BB184010
gene
Atp1a3 Atp1a3 ATPase, Na+/K+ transporting, 1.2 0.5 BC020177
alpha 3 polypeptide
Atp6v1e1 Atp6v1e1 ATPase, H+ transporting, V1 0.7 0.4 C85064
subunit E isoform 1
— AW112010 Mus musculus transcribed 32.5 4.1 BE688358
sequences
B230106I24Rik B230106I24Rik RIKEN cDNA B230106I24 0.8 0.3 AV369935
gene
B230106I24Rik B230106I24Rik RIKEN cDNA B230106I24 1.0 0.5 AV369935
gene
B2m B2m beta-2 microglobulin 11.6 2.0 AA170322
B3galt5 B3galt5 UDP-Gal:betaGlcNAc beta 0.4 0.2 NM_033149
1,3-galactosyltransferase,
polypeptide 5
Bak1 Bak1 BCL2-antagonist/killer 1 2.1 0.5 AF402617
BC005471 BC005471 cDNA sequence BC005471 1.5 0.7 BC005471
BC010462 BC010462 cDNA sequence BC010462 3.5 0.3 BC010462
BC013712 BC013712 cDNA sequence BC013712 12.3 4.1 BB262491
BC014805 BC014805 cDNA sequence BC014805 0.7 0.2 AJ132857
BC022687 BC022687 cDNA sequence BC022687 0.3 0.2 BC022687
BC023105 BC023105 cDNA sequence BC023105 70.3 0.7 BC023105
BC026585 BC026585 cDNA sequence BC026585 0.2 0.1 BC026585
L259 BC028528 L259 4.1 1.8 BC028528
2310015I10Rik Brd4 RIKEN cDNA 2310015I10 13.8 2.8 BC008532
gene
C1r C1r complement component 1, r 9.4 3.8 NM_023143
subcomponent
C1s C1s complement component 1, s 12.7 2.8 BC022123
subcomponent
C2 C2 complement component 2 3.5 0.9 NM_013484
(within H-2S)
— C2 — 4.6 0.9 AV290571
— C2 — 4.4 1.1 AV227574
C230080I20Rik C230080I20Rik RIKEN cDNA C230080I20 0.6 0.2 BB795533
gene
C2ta C2ta class II transactivator 13.2 1.6 AF042158
C2ta C2ta class II transactivator 10.8 1.5 AF042158
C330005L02Rik C330005L02Rik RIKEN cDNA C330005L02 0.9 0.4 BE134115
gene
C6.1A C6.1A c6.1a protein 0.9 0.5 AI462244
— C730040L01Rik Mus musculus 10 days 1.3 0.2 BB391874
neonate cortex cDNA, RIKEN
full-length enriched library,
clone: A830089I03
product: hypothetical KRAB
box containing protein, full
insert sequence
Car5b Car5b carbonic anhydrase 5b, 1.1 0.4 NM_019513
mitochondrial
Card11 Card11 caspase recruitment domain 4.6 2.0 AV095659
family, member 11
Casp1 Casp1 caspase 1 9.4 2.2 BC008152
Casp12 Casp12 caspase 12 3.6 1.7 NM_009808
Casp4 Casp4 caspase 4, apoptosis-related 13.6 6.8 NM_007609
cysteine protease
Cbs Cbs cystathionine beta-synthase 0.6 0.1 BC026595
Cbx5 Cbx5 chromobox homolog 5 0.9 0.4 NM_007626
(Drosophila HP1a)
Ccl19 Ccl19 chemokine (C-C motif) ligand 1.8 0.1 NM_011888
19
Ccl21a Ccl21a chemokine (C-C motif) ligand 0.9 0.1 NM_011335
21a (serine)
— Ccl27 — 0.7 0.1 BQ174669
Ccl27 Ccl27 chemokine (C-C motif) ligand 0.6 0.2 NM_011336
27
Ccl28 Ccl28 chemokine (C-C motif) ligand 0.9 0.0 BG867337
28
Ccl28 Ccl28 chemokine (C-C motif) ligand 1.1 0.3 BE196980
28
Ccl28 Ccl28 chemokine (C-C motif) ligand 0.9 0.1 BG867337
28
Ccl5 Ccl5 chemokine (C-C motif) ligand 5 140.5 9.6 NM_013653
Ccl8 Ccl8 chemokine (C-C motif) ligand 8 16.0 6.2 NM_021443
Ccr9 Ccr9 chemokine (C-C motif) 2.1 0.6 NM_009913
receptor 9
Mox2 Cd200 antigen identified by 2.2 1.0 AF004023
monoclonal antibody MRC
OX-2
Cd86 Cd86 CD86 antigen 10.4 4.5 NM_019388
— Cdca3 — 1.7 0.7 AV352659
Cds1 Cds1 CDP-diacylglycerol synthase 1 2.0 0.9 BI152841
4932437H03 Cenpj hypothetical protein 1.2 0.6 BG068259
4932437H03
Chpt1 Chpt1 choline phosphotransferase 1 0.5 0.2 BC016251
Clrf Clec2h; Clrf C-type lectin related f 0.1 0.0 AK017207
Clic5 Clic5 chloride intracellular channel 5 0.7 0.1 BB610000
Clic5 Clic5 chloride intracellular channel 5 0.8 0.2 AA210377
Clic5 Clic5 chloride intracellular channel 5 1.1 0.2 BB028501
Clrf Clrf C-type lectin related f 0.2 0.0 AF350410
Cml5 Cml5 camello-like 5 0.6 0.2 BC024605
Arvcf Comt armadillo repeat gene deleted 0.8 0.2 NM_007744
in velo-cardio-facial syndrome
Cpeb4 Cpeb4 cytoplasmic polyadenylation 0.9 0.4 NM_026252
element binding protein 4
— Cpt2 — 1.1 0.5 AV236319
Csprs Csprs component of Sp100-rs 1.4 0.1 NM_033616
Csprs Csprs component of Sp100-rs 1.8 0.1 BB148221
2210401K11Rik Ctbs RIKEN cDNA 2210401K11 0.6 0.3 BC022594
gene
2210401K11Rik Ctbs RIKEN cDNA 2210401K11 0.8 0.4 BC022594
gene
Cxcl10 Cxcl10 chemokine (C—X—C motif) 81.6 3.1 NM_021274
ligand 10
Cxcl11 Cxcl11 chemokine (C—X—C motif) 99.2 3.6 NM_019494
ligand 11
Cxcl9 Cxcl9 chemokine (C—X—C motif) 176.4 0.2 NM_008599
ligand 9
Cxcr3 Cxcr3 chemokine (C—X—C motif) 10.2 2.6 NM_009910
receptor 3
Cybb Cybb cytochrome b-245, beta 14.2 5.9 NM_007807
polypeptide
Cyp4v3 Cyp4v3 cytochrome P450, family 4, 3.9 1.8 NM_133969
subfamily v, polypeptide 3
— D030011O10Rik Mus musculus transcribed 0.6 0.3 BE994639
sequence with weak
similarity to protein pir: T17242
(H. sapiens) T17242
hypothetical protein
DKFZp586B1417.1 - human
(fragment)
D11Ertd759e D11Ertd759e DNA segment, Chr 11, 4.9 1.8 AW556558
ERATO Doi 759, expressed
D11Lgp2e D11Lgp2e DNA segment, Chr 11, Lothar 6.1 0.6 NM_030150
Hennighausen 2, expressed
D11Lgp2e D11Lgp2e DNA segment, Chr 11, Lothar 10.0 2.3 AF316999
Hennighausen 2, expressed
— D12Ertd551e Mus musculus adult male 5.5 2.3 BQ175646
tongue cDNA, RIKEN full-
length enriched library,
clone: 2310058N22
product: unknown EST, full
insert sequence
D12Ertd647e D12Ertd647e DNA segment, Chr 12, 5.8 1.8 AW554405
ERATO Doi 647, expressed
D12Ertd647e D12Ertd647e DNA segment, Chr 12, 4.1 1.4 BI655075
ERATO Doi 647, expressed
— D12Ertd771e Mus musculus 13 days 1.3 0.6 BB392503
embryo male testis cDNA,
RIKEN full-length enriched
library, clone: 6030490B17
product: unknown EST, full
insert sequence
D5Ertd135e D5Ertd135e DNA segment, Chr 5, ERATO 0.5 0.3 BB401993
Doi 135, expressed
D7Bwg0421e D7Bwg0421e DNA segment, Chr 7, 8.1 2.7 BB667693
Brigham & Women's Genetics
0421 expressed
2210404A22Rik D8Ertd594e RIKEN cDNA 2210404A22 0.9 0.3 AK008821
gene
Ddx47 Ddx47 DEAD (Asp-Glu-Ala-Asp) box 0.4 0.1 BB305306
polypeptide 47
Defcr9 Defcr9 defensin related cryptdin 9 1.4 0.5 U03065
Dnase1l3 Dnase1l3 deoxyribonuclease 1-like 3 6.4 0.4 BC012671
Dnase1l3 Dnase1l3 deoxyribonuclease 1-like 3 8.8 0.9 BC012671
D14Wsu89e Dock9 DNA segment, Chr 14, 0.6 0.2 BB795072
Wayne State University 89,
expressed
Dsg2 Dsg2 desmoglein 2 1.9 0.9 C79957
Dsg2 Dsg2 desmoglein 2 1.3 0.6 AB072269
— Dtx3l Mus musculus transcribed 9.1 2.1 AV327407
sequence with weak
similarity to protein
ref: NP_081764.1
(M. musculus) RIKEN cDNA
5730493B19 [Mus musculus]
E130309F12Rik E130309F12Rik RIKEN cDNA E130309F12 0.7 0.0 BB523550
gene
E430019B13Rik E430019B13Rik RIKEN cDNA E430019B13 2.2 0.9 BE630983
gene
1300018P11Rik Eif4e3 RIKEN cDNA 1300018P11 5.1 2.4 BC027014
gene
2810013J18Rik Eme2 RIKEN cDNA 2810013J18 1.0 0.4 AK012738
gene
Entpd5 Entpd5 ectonucleoside triphosphate 0.4 0.2 NM_007647
diphosphohydrolase 5
Entpd5 Entpd5 ectonucleoside triphosphate 0.4 0.2 NM_007647
diphosphohydrolase 5
Entpd5 Entpd5 ectonucleoside triphosphate 0.4 0.2 AF136571
diphosphohydrolase 5
Entpd5 Entpd5 ectonucleoside triphosphate 0.5 0.2 NM_007647
diphosphohydrolase 5
2310046K10Rik Epsti1 RIKEN cDNA 2310046K10 13.4 3.8 AK017174
gene
Etv1 Etv1 ets variant gene 1 0.4 0.1 NM_007960
2610104C07Rik Exosc1 RIKEN cDNA 2610104C07 1.2 0.6 BC024423
gene
Fabp7 Fabp7 fatty acid binding protein 7, 5.2 0.3 NM_021272
brain
1110064L07Rik Fbxw17 RIKEN cDNA 1110064L07 4.8 2.3 AV016303
gene
Fcrl3 Fcrl3 Fc receptor-like 3 20.5 5.4 BC027310
Fgl2 Fgl2 fibrinogen-like protein 2 28.1 3.9 BF136544
Fgl2 Fgl2 fibrinogen-like protein 2 46.7 5.6 BF136544
1110008K06Rik Fln29 RIKEN cDNA 1110008K06 4.0 1.6 AK003586
gene
Fmo4 Fmo4 flavin containing 0.4 0.0 AF461145
monooxygenase 4
Fmo5 Fmo5 flavin containing 0.3 0.1 NM_010232
monooxygenase 5
Fmr1 Fmr1 fragile X mental retardation 1.2 0.6 AF461114
syndrome 1 homolog
6030440G05Rik Frmd4b RIKEN cDNA 6030440G05 0.7 0.3 BM119551
gene
— Gabra2 Mus musculus transcribed 0.9 0.4 BB433285
sequences
A530057M15Rik Galm RIKEN cDNA A530057M15 0.6 0.3 AV307219
gene
Gbp2 Gbp2 guanylate nucleotide binding 53.4 2.3 BE197524
protein 2
Gbp2 Gbp2 guanylate nucleotide binding 100.2 2.9 NM_010260
protein 2
Gbp3 Gbp4 guanylate nucleotide binding 42.9 7.5 NM_018734
protein 3
Gca Gca grancalcin 1.2 0.5 BC021450
Gca Gca grancalcin 1.5 0.4 BC021450
Ghr Ghr growth hormone receptor 0.5 0.2 M33324
Ian1 Gimap4 immune associated 3.0 1.1 BC005577
nucleotide 1
Ian1 Gimap4 immune associated 2.4 0.9 BC005577
nucleotide 1
Ian3 Gimap7 immune associated 14.1 5.4 BC026200
nucleotide 3
Glipr1 Glipr1 GLI pathogenesis-related 1 14.8 7.4 BC025083
(glioma)
Gnb4 Gnb4 guanine nucleotide binding 2.1 1.0 BI713933
protein, beta 4
Gpr1 Gpr1 G protein-coupled receptor 1 1.2 0.5 AW541072
Gpr18 Gpr18 G protein-coupled receptor 18 9.9 3.4 BG145550
1810036L03Rik Gsdmdc1 RIKEN cDNA 1810036L03 6.5 2.5 AK007710
gene
Gstt2 Gstt2 glutathione S-transferase, 0.7 0.3 BC012707
theta 2
Gzmk Gzmk granzyme K 14.1 3.9 AB032200
H28 H28 histocompatibility 28 1.6 0.5 NM_031367
H28 H28 histocompatibility 28 6.8 1.1 BC024930
H28 H28 histocompatibility 28 8.9 1.1 NM_031367
— H2-Aa — 46.1 10.5 AV086906
H2-Ab1 H2-Ab1 histocompatibility 2, class II 13.2 4.0 NM_010379
antigen A, beta 1
H2-Bl H2-Bl histocompatibility 2, 1.6 0.5 NM_008199
blastocyst
H2-D1 H2-D1 histocompatibility 2, D region 6.2 0.0 NM_010380
locus 1
H2-DMb1 H2-DMb1 histocompatibility 2, class II, 19.8 3.8 NM_010387
locus Mb1
H2-DMb1 H2-DMb1 histocompatibility 2, class II, 38.0 4.3 NM_010388
locus Mb1
H2-DMb1 H2-DMb1 histocompatibility 2, class II, 45.2 4.8 BB734586
locus Mb1
H2-K H2-K1 histocompatibility 2, K region 22.5 7.1 L23495
— H2-K1 MHC I = H-2Kd homolog 45.5 10.8 S70184
{alternatively spliced, deletion
of exon 3} [mice, DBA/2,
L1210 lymphoma, mRNA
Mutant, 855 nt]
H2-M3 H2-M3 histocompatibility 2, M region 4.8 2.0 NM_013819
locus 3
H2-Oa H2-Oa histocompatibility 2, O region 6.1 1.4 NM_008206
alpha locus
H2-Ob H2-Ob histocompatibility 2, O region 4.4 1.1 BG144448
beta locus
H2-Q1 H2-Q1 histocompatibility 2, Q region 22.6 3.1 BC010602
locus 1
H2-Q7 H2-Q7 histocompatibility 2, Q region 78.5 24.8 M29881
locus 7
H2-T10 H2-T10 histocompatibility 2, T region 4.3 0.7 NM_010395
locus 10
H2-T23 H2-T23 histocompatibility 2, T region 8.0 0.9 NM_010398
locus 23
— H2-T23 Mus musculus 2 days 6.6 1.3 NM_010398
neonate thymus thymic cells
cDNA, RIKEN full-length
enriched library,
clone: C920026N01
product: weakly similar to H-2
CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-37 ALPHA
CHAIN PRECURSOR [Mus
musculus], full insert
sequence
H2-T24 H2-T24 histocompatibility 2, T region 3.1 0.6 L22338
locus 24
Hadhsc Hadhsc L-3-hydroxyacyl-Coenzyme A 0.4 0.1 BB114220
dehydrogenase, short chain
Hdc Hdc histidine decarboxylase 0.9 0.1 BG072171
Hdc Hdc histidine decarboxylase 0.9 0.1 AF109137
Helic1 Helic1 helicase, ATP binding 1 1.4 0.6 BB501662
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 20.4 1.2 AI639807
gene
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 18.0 2.0 AK015214
gene
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 12.8 1.0 AI639807
gene
2510038N07Rik Herc5 RIKEN cDNA 2510038N07 25.4 1.9 AW208668
gene
— Hk3 — 14.9 4.0 BB324660
— Hnrpm Mus musculus transcribed 0.9 0.4 AW493461
sequences
Hpse Hpse heparanase 22.8 11.4 BG094050
Hrasls3 Hrasls3 HRAS like suppressor 3 16.5 0.8 BC024581
Hsd11b1 Hsd11b1 hydroxysteroid 11-beta 0.3 0.2 NM_008288
dehydrogenase 1
Hsf2bp Hsf2bp heat shock transcription factor 0.6 0.2 AK016553
2 binding protein
Icsbp1 Icsbp1 interferon consensus 9.9 2.8 BG069095
sequence binding protein 1
Icsbp1 Icsbp1 interferon consensus 10.0 3.7 BG069095
sequence binding protein 1
Idh1 Idh1 isocitrate dehydrogenase 1 0.8 0.3 AI788952
(NADP+), soluble
Ifi1 Ifi1 interferon inducible protein 1 15.4 1.1 NM_008326
Ifi202b Ifi202b interferon activated gene 42.5 5.8 AV229143
202B
Ifi202b Ifi202b interferon activated gene 46.5 3.2 NM_011940
202B
Ifi203 Ifi203 interferon activated gene 203 17.8 8.8 NM_008328
Ifi203 Ifi203 interferon activated gene 203 9.1 2.7 BC008167
Ifi16 Ifi204 interferon, gamma-inducible 24.8 5.5 NM_008329
protein 16
Ifi205 Ifi205 interferon activated gene 205 151.7 40.3 M74124
Ifi205 Ifi205 interferon activated gene 205 102.7 10.1 AI481797
Ifi205 Ifi205 interferon activated gene 205 79.7 13.6 AI481797
2010008K16Rik Ifi35 RIKEN cDNA 2010008K16 4.5 1.7 BC008158
gene
2010008K16Rik Ifi35 RIKEN cDNA 2010008K16 6.0 2.3 AW986054
gene
A430056A10Rik Ifi44 RIKEN cDNA A430056A10 5.0 0.7 BB329808
gene
9130009C22Rik Ifih1 RIKEN cDNA 9130009C22 5.4 1.7 AY075132
gene
Ifit1 Ifit1 interferon-induced protein 18.5 3.5 NM_008331
with tetratricopeptide repeats 1
Ifit2 Ifit2 interferon-induced protein 33.8 2.0 NM_008332
with tetratricopeptide repeats 2
Ifit3 Ifit3 interferon-induced protein 6.3 0.6 NM_010501
with tetratricopeptide repeats 3
Ifng Ifng interferon gamma 30.3 2.5 K00083
Igf1 Igf1 insulin-like growth factor 1 2.7 1.1 NM_010512
Igf1 Igf1 insulin-like growth factor 1 2.0 0.9 BG075165
Igh-6 Igh-6 immunoglobulin heavy chain 6.0 1.9 AI326478
6 (heavy chain of IgM)
Igk-V1 Igk-V1 immunoglobulin kappa chain 1.4 0.2 U29768
variable 1 (V1)
Igk-V8 Igk-V8 immunoglobulin kappa chain 1.5 0.2 BI107286
variable 8 (V8)
Igsf7 Igsf7 immunoglobulin superfamily, 7.0 3.4 AF251705
member 7
Igtp Igtp interferon gamma induced 25.9 0.8 NM_018738
GTPase
— Igtp Mus musculus 13 days 14.3 1.0 BB485297
embryo lung cDNA, RIKEN
full-length enriched library,
clone: D430030N05
product: unknown EST, full
insert sequence
AI481100 Igtp expressed sequence 30.9 1.2 NM_019440
AI481100
AW111922 Iigp1 expressed sequence 36.6 0.6 BM239828
AW111922
AW111922 Iigp1 expressed sequence 53.7 0.7 BM239828
AW111922
Il12b Il12b interleukin 12b 1.7 0.3 AF128214
Il12rb1 Il12rb1 interleukin 12 receptor, beta 1 5.5 2.6 NM_008353
Il15 Il15 interleukin 15 1.0 0.2 NM_008357
Il18 Il18 interleukin 18 2.1 0.9 NM_008360
Il18bp Il18bp interleukin 18 binding protein 33.6 1.5 AF110803
Temt Inmt thioether S-methyltransferase 0.2 0.0 NM_009349
B430217B02Rik Irf1 RIKEN cDNA B430217B02 15.7 2.2 NM_008390
gene
Irf7 Irf7 interferon regulatory factor 7 9.8 2.9 NM_016850
Irg1 Irg1 immunoresponsive gene 1 80.3 31.1 L38281
Itga4 Itga4 integrin alpha 4 8.5 3.3 NM_010576
Itm2a Itm2a integral membrane protein 2A 1.1 0.5 BI966443
Itm2a Itm2a integral membrane protein 2A 1.0 0.4 BI966443
Itpka Itpka inositol 1,4,5-trisphosphate 3- 1.7 0.9 BC027291
kinase A
Klra2 Klra2 killer cell lectin-like receptor, 14.3 2.5 NM_008462
subfamily A, member 2
Klra7 Klra7 killer cell lectin-like receptor, 7.9 1.8 U10095
subfamily A, member 7
Klra8 Klra8 killer cell lectin-like receptor, 5.5 0.9 U12889
subfamily A, member 8
Klra3 Klra9 killer cell lectin-like receptor, 6.5 1.9 U49865
subfamily A, member 3
Klrb1d Klrb1d killer cell lectin-like receptor 4.6 1.3 AF342896
subfamily B member 1D
Klrb1d Klrb1d killer cell lectin-like receptor 9.8 3.3 NM_008526
subfamily B member 1D
Klrc1 Klrc1 killer cell lectin-like receptor 19.3 7.6 AF106009
subfamily C, member 1
Klrk1 Klrk1 killer cell lectin-like receptor 21.5 3.5 AF039026
subfamily K, member 1
D7Bwg0421e Lair1 DNA segment, Chr 7, 11.9 4.0 AK017222
Brigham & Women's Genetics
0421 expressed
— Leprel1 Mus musculus 12 days 0.9 0.4 BB105009
embryo embryonic body
between diaphragm region
and neck cDNA, RIKEN full-
length enriched library,
clone: 9430093N11
product: unknown EST, full
insert sequence
Letm1 Letm1 leucine zipper-EF-hand 0.6 0.3 BG060855
containing transmembrane
protein 1
Lgals8 Lgals8 lectin, galactose binding, 1.1 0.5 AI987967
soluble 8
— Lmtk2 Mus musculus transcribed 1.2 0.3 BB449235
sequence with strong
similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
LOC207685 LOC207685 hypothetical protein 2.7 0.5 AK008551
LOC207685
LOC209387 LOC209387 tripartite motif protein 30-like 20.2 7.5 BM241342
LOC223672 LOC223672 hypothetical protein 25.0 0.7 BC020489
LOC223672
Ly6c Ly6c lymphocyte antigen 6 2.8 1.0 NM_010741
complex, locus C
Ly6i Ly6i lymphocyte antigen 6 15.4 0.4 AF232024
complex, locus I
Ly86 Ly86 lymphocyte antigen 86 24.1 11.6 NM_010745
2410018D16Rik Mat2b RIKEN cDNA 2410018D16 1.0 0.5 NM_134017
gene
— MDABG2-4 Mus musculus nucleosome- 2.0 0.6 AB007986
reactive monoclonal antibody
PR1-3, Ig light chain variable
region mRNA, partial cds.
Mgat3 Mgat3 mannoside 0.2 0.1 NM_010795
acetylglucosaminyltransferase 3
MGC25972 MGC25972 similar to cytochrome P450, 0.4 0.1 BC025936
4a10
Mia2 Mia2 melanoma inhibitory activity 2 0.9 0.3 AF390177
— Mpa2l Mus musculus transcribed 72.1 1.7 BG092512
sequences
— Mpa2l Mus musculus transcribed 118.4 1.5 BM241485
sequence with weak
similarity to protein sp: P32456
(H. sapiens) GBP2_HUMAN
Interferon-induced guanylate-
binding protein 2 (Guanine
nucleotide-binding protein 2)
Mpeg1 Mpeg1 macrophage expressed gene 1 22.7 6.9 L20315
Ms4a1 Ms4a1 membrane-spanning 4- 4.0 2.0 BB236617
domains, subfamily A,
member 1
Ms4a4b Ms4a4b membrane-spanning 4- 56.0 11.5 BB199001
domains, subfamily A,
member 4B
Ms4a4d Ms4a4d membrane-spanning 4- 12.6 0.7 NM_025658
domains, subfamily A,
member 4D
Ms4a6b Ms4a6b membrane-spanning 4- 45.7 15.7 NM_027209
domains, subfamily A,
member 6B
Ms4a6c Ms4a6c membrane-spanning 4- 14.8 5.8 AF237910
domains, subfamily A,
member 6C
Mtac2d1 Mtac2d1 membrane targeting (tandem) 0.4 0.1 BB548141
C2 domain containing 1
Mtap7 Mtap7 microtubule-associated 1.2 0.6 AK006385
protein 7
Mx1 Mx1 myxovirus (influenza virus) 6.9 1.8 M21039
resistance 1
— Net1 Mus musculus transcribed 4.1 1.2 AV247312
sequences
Ngfr Ngfr nerve growth factor receptor 8.3 3.1 BB151515
(TNFR superfamily, member
16)
Nmi Nmi N-myc (and STAT) interactor 6.7 1.4 BC002019
Nt5c2 Nt5c2 5′-nucleotidase, cytosolic II 1.1 0.4 BI202534
Nt5c2 Nt5c2; GMP; 5′-nucleotidase, cytosolic II 1.6 0.7 BC006028
NT5B; PNT5;
cN-II;
2010002I23Rik
Oas1g Oas1a 2′-5′ oligoadenylate 6.9 2.4 BC018470
synthetase 1G
Oasl2 Oasl2 2′-5′ oligoadenylate 17.4 1.9 BQ033138
synthetase-like 2
Og9x Og9x OG9 homeobox gene 0.7 0.4 BB705267
BC047207 Olfml1 cDNA sequence BC047207 0.7 0.3 BB055163
Olfr56 Olfr56 olfactory receptor 56 39.5 2.3 NM_008330
A130090K04Rik Oprm1 RIKEN cDNA A130090K04 1.3 0.4 BB703415
gene
A130090K04Rik Oprm1 RIKEN cDNA A130090K04 3.1 1.1 BQ176089
gene
Osbpl6 Osbpl6 oxysterol binding protein-like 6 0.5 0.2 BG070848
Paip1 Paip1 polyadenylate binding protein- 0.8 0.1 BB381990
interacting protein 1
Paip1 Paip1 polyadenylate binding protein- 0.9 0.0 BC019726
interacting protein 1
5330431N24Rik Parp11 RIKEN cDNA 5330431N24 3.1 1.3 BB026163
gene
BC021340 Parp14 cDNA sequence BC021340 16.1 3.0 BC021340
Adprtl3 Parp3 ADP-ribosyltransferase 2.6 0.8 BC014870
(NAD+; poly (ADP-ribose
polymerase)-like 3
Adprtl3 Parp3 ADP-ribosyltransferase 2.1 1.0 AW990611
(NAD+; poly (ADP-ribose
polymerase)-like 3
BC003281 Parp9 cDNA sequence BC003281 12.0 2.9 NM_030253
1110035O14Rik Pbef1 RIKEN cDNA 1110035O14 2.4 1.0 AW989410
gene
Pclo Pclo piccolo (presynaptic 0.6 0.1 AW493746
cytomatrix protein)
Pdcd1lg1 Pdcd1lg1 programmed cell death 1 45.1 4.7 NM_021893
ligand 1
Pde9a Pde9a phosphodiesterase 9A 0.6 0.3 NM_008804
Pdzk1 Pdzk1; Pdzd1; PDZ domain containing 1 0.4 0.2 AK006269
mPDZK1;
D3Ertd537e;
1700023D20Rik;
2610507N21Rik;
4921513F16Rik
Peli1 Peli1 pellino 1 2.1 1.0 BC016515
4933417L10Rik Phf11 RIKEN cDNA 4933417L10 4.8 1.1 AV280841
gene
Phip Phip pleckstrin homology domain 1.3 0.5 BI737352
interacting protein
Pigr Pigr polymeric immunoglobulin 4.4 1.7 AV027632
receptor
Pigr Pigr polymeric immunoglobulin 3.0 1.2 NM_011082
receptor
— Pink1 — 0.4 0.2 AV371921
— Plec1 Mus musculus similar to 1.4 0.5 BI525140
Plec1 protein (LOC381010),
mRNA
Pnp Pnp purine-nucleoside 2.2 0.8 AK008143
phosphorylase
Mt1a Polr2k metallothionein-I activator 0.9 0.4 AA175187
Ppargc1 Ppargc1a peroxisome proliferative 0.5 0.2 BB745167
activated receptor, gamma,
coactivator 1
— Ppt1 Mus musculus 12 days 3.0 0.6 BB461203
embryo spinal ganglion
cDNA, RIKEN full-length
enriched library,
clone: D130070K05
product: unknown EST, full
insert sequence
Ppt1 Ppt1 palmitoyl-protein thioesterase 1 1.0 0.5 AF326558
Prkr Prkr protein kinase, interferon- 5.0 2.0 BE911144
inducible double stranded
RNA dependent
— Prok1 Mus musculus 3 days 0.6 0.3 BE651535
neonate thymus cDNA,
RIKEN full-length enriched
library, clone: A630076J17
product: unclassifiable, full
insert sequence
Psmb10 Psmb10 proteasome (prosome, 14.7 3.6 NM_013640
macropain) subunit, beta type
10
Psmb8 Psmb8 proteosome (prosome, 27.5 4.1 NM_010724
macropain) subunit, beta type
8 (large multifunctional
protease 7)
Psmb8 Psmb8 proteosome (prosome, 24.0 3.4 AV068122
macropain) subunit, beta type
8 (large multifunctional
protease 7)
Psmb9 Psmb9 proteosome (prosome, 30.2 2.1 NM_013585
macropain) subunit, beta type
9 (large multifunctional
protease 2)
Tap1 Psmb9 transporter 1, ATP-binding 29.5 3.9 AW048052
cassette, sub-family B
(MDR/TAP)
Psme1 Psme1 proteasome (prosome, 3.1 1.5 NM_011189
macropain) 28 subunit, alpha
Psme2 Psme2 proteasome (prosome, 5.3 1.9 NM_011190
macropain) 28 subunit, beta
Psme4 Psme4 proteasome (prosome, 0.8 0.3 BG075584
macropain) activator subunit 4
— Ptbp2 Mus musculus 16 days 1.3 0.6 BB155176
neonate thymus cDNA,
RIKEN full-length enriched
library, clone: A130023P20
product: unclassifiable, full
insert sequence
Ptprcap Ptprcap protein tyrosine phosphatase, 7.5 3.5 NM_016933
receptor type, C polypeptide-
associated protein
— Ptprk Mus musculus transcribed 1.0 0.4 BG802688
sequences
2410027J01Rik Qprt RIKEN cDNA 2410027J01 0.6 0.1 AI195046
gene
— Rab11fip3 Mus musculus 0 day neonate 0.4 0.2 BQ266518
kidney cDNA, RIKEN full-
length enriched library,
clone: D630036H09
product: similar to EFERIN
[Homo sapiens], full insert
sequence
Rab17 Rab17 RAB17, member RAS 0.6 0.3 NM_008998
oncogene family
Rab19 Rab19 RAB19, member RAS 2.8 0.9 BM241400
oncogene family
Rbl1 Rbl1 retinoblastoma-like 1 (p107) 5.8 2.2 U27177
— Rkhd2 Mus musculus 16 days 0.8 0.2 BB369687
embryo head cDNA, RIKEN
full-length enriched library,
clone: C130049H14
product: unknown EST, full
insert sequence
4930474F22Rik Rnase10 RIKEN cDNA 4930474F22 1.2 0.3 AK015573
gene
Rnaset2 Rnaset2; ribonuclease T2 2.2 0.6 AK015947
RNASE6PL;
0610007O07Rik;
4833423A10Rik;
4930532K22Rik
Samhd1 Samhd1 SAM domain and HD domain, 1 16.3 5.3 AV376100
Samhd1 Samhd1 SAM domain and HD domain, 1 11.4 4.1 BF148012
Samhd1 Samhd1 SAM domain and HD domain, 1 11.3 2.7 NM_018851
D11Moh48 Scrn2 DNA segment, Chr 11, KL 0.3 0.1 BC021346
Mohlke 48
D11Moh48 Scrn2 DNA segment, Chr 11, KL 0.3 0.1 BB735480
Mohlke 48
Sec8 Sec8l1 SEC8 (S. cerevisiae) 0.9 0.4 AK010695
Sectm1 Sectm1 secreted and transmembrane 1 3.0 0.0 AI481997
Sell Sell selectin, lymphocyte 14.0 6.5 M36005
Sell Sell selectin, lymphocyte 9.7 4.7 M36005
Serpina10 Serpina10 serine (or cysteine) 44.0 17.5 BC018416
proteinase inhibitor, clade A
(alpha-1 antiproteinase,
antitrypsin), member 10
Sfrp1 Sfrp1 secreted frizzled-related 0.5 0.2 BI658627
sequence protein 1
Sfrp1 Sfrp1 secreted frizzled-related 0.5 0.2 BI658627
sequence protein 1
Sgcb Sgcb sarcoglycan, beta (dystrophin- 0.9 0.3 AK014381
associated glycoprotein)
Slamf7 Slamf7 SLAM family member 7 5.4 1.1 AK016183
Slamf8 Slamf8 SLAM family member 8 65.9 9.5 BC024587
1200003C15Rik Slc16a9 RIKEN cDNA 1200003C15 0.3 0.1 AK004684
gene
1200003C15Rik Slc16a9 RIKEN cDNA 1200003C15 0.4 0.1 AK004684
gene
Slc18a1 Slc18a1 solute carrier family 18 0.3 0.1 BB011871
(vesicular monoamine),
member 1
Slc1a1 Slc1a1 solute carrier family 1, 0.5 0.2 AF087578
member 1
Slc1a4 Slc1a4 solute carrier family 1 1.8 0.6 BB277461
(glutamate/neutral amino acid
transporter), member 4
Slc1a4 Slc1a4 solute carrier family 1 1.5 0.6 BB277461
(glutamate/neutral amino acid
transporter), member 4
Slc22a5 Slc22a5 solute carrier family 22 0.4 0.2 NM_011396
(organic cation transporter),
member 5
Slc26a7 Slc26a7 solute carrier family 26, 0.5 0.2 AV292356
member 7
Slc2a5 Slc2a5 solute carrier family 2 0.2 0.0 NM_019741
(facilitated glucose
transporter), member 5
A230035L05Rik Slc41a2 RIKEN cDNA A230035L05 2.3 1.0 BC026874
gene
AI315119 Slc5a12 expressed sequence 0.3 0.1 BB503566
AI315119
Xtrp2 Slc6a18 X transporter protein 2 0.7 0.3 AF075266
4632401C08Rik Slc6a19 RIKEN cDNA 4632401C08 0.4 0.1 AK014544
gene
4632401C08Rik Slc6a19 RIKEN cDNA 4632401C08 0.4 0.1 BM119683
gene
Slco1a1 Slco1a1 solute carrier organic anion 0.2 0.0 AB031813
transporter family, member
1a1
Slfn8 Slfn8 schlafen 8 8.6 2.7 BC024709
Smpdl3a Smpdl3a sphingomyelin 0.6 0.2 NM_020561
phosphodiesterase, acid-like
3A
Snx10 Snx10 sorting nexin 10 20.8 8.4 AK010399
Sod3 Sod3 superoxide dismutase 3, 0.3 0.1 NM_011435
extracellular
Sostdc1 Sostdc1 sclerostin domain containing 1 0.4 0.2 BC021458
Srd5a2l Srd5a2l steroid 5 alpha-reductase 2- 1.1 0.4 BB825787
like
— Ss18 Mus musculus transcribed 1.1 0.5 BB199855
sequences
— Stat1 Mus musculus transcribed 19.6 1.4 BB229853
sequences
Stat1 Stat1 signal transducer and 22.7 1.1 AW214029
activator of transcription 1
Stat1 Stat1 signal transducer and 14.1 1.1 AW214029
activator of transcription 1
Stat1 Stat1 signal transducer and 23.0 2.0 AW214029
activator of transcription 1
Stat2 Stat2 signal transducer and 6.1 1.7 AF088862
activator of transcription 2
Stat2 Stat2 signal transducer and 3.2 1.3 AF088862
activator of transcription 2
4921538B17Rik Steap2 RIKEN cDNA 4921538B17 1.2 0.5 BB529332
gene
Mrpl16 Stx3 mitochondrial ribosomal 0.6 0.1 D29800
protein L16
Sult1c1 Sult1c2 sulfotransferase family, 0.5 0.2 NM_026935
cytosolic, 1C, member 1
Syn2 Syn2 synapsin II 0.3 0.1 NM_013681
Syt1 Syt1 synaptotagmin 1 2.1 0.9 BM118245
Tap2 Tap2 transporter 2, ATP-binding 11.2 2.5 BE691515
cassette, sub-family B
(MDR/TAP)
Tapbp Tapbp TAP binding protein 4.6 1.0 AF043943
Tapbp Tapbp TAP binding protein 5.5 2.1 AF043943
LOC213233 Tapbpl similar to hypothetical protein 5.3 1.5 BC017613
FLJ10143
4432405K22Rik Tbc1d15 RIKEN cDNA 4432405K22 1.2 0.6 BF577643
gene
Tcf7 Tcf7 transcription factor 7, T-cell 13.5 4.5 AI323642
specific
— TCR beta-chain M. musculus mRNA for Tcell 8.2 2.4 M87849
receptor, V-J beta junctional
region (clone T1CRP8)
— Tcra Mus musculus T cell receptor 9.2 3.9 X01134
alpha chain variable region
(TCRAV3S9) mRNA, partial
cds
— Tcra Mus musculus adult male 7.7 3.0 U07662
thymus cDNA, RIKEN full-
length enriched library,
clone: 5830404G23 product: T-
cell receptor alpha chain
precursor V-J region (TA72)
(fragment) homolog [Mus
musculus], full insert
sequence
— Tcra Mus musculus adult male 1.7 0.7 BB032962
thymus cDNA, RIKEN full-
length enriched library,
clone: 5830474E17 product: T-
cell receptor alpha chain
precursor V-J region (TA72)
(fragment) homolog [Mus
musculus], full insert
sequence
— Tcrb-J; — 3.1 0.5 AK018014
5830405F06Rik
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 55.0 25.2 U07661
13
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 55.9 21.5 M11456
13
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 6.8 1.0 U46841
13
Tcrb-V13 Tcrb-V13 T-cell receptor beta, variable 75.1 29.5 X67128
13
Tex9 Tex9 testis expressed gene 9 1.3 0.4 AK008505
— Tgfbr2 Mus musculus transcribed 2.4 0.6 BB465968
sequences
Tgtp Tgtp T-cell specific GTPase 24.4 1.7 NM_011579
Timp3 Timp3 tissue inhibitor of 0.5 0.2 BI111620
metalloproteinase 3
Syn2 Timp4 synapsin II 0.5 0.2 AK013810
Tlr3 Tlr3 toll-like receptor 3 3.9 1.2 NM_126166
1810015P03Rik Tmed6 RIKEN cDNA 1810015P03 0.5 0.2 NM_025458
gene
2810428F02Rik Tmem19 RIKEN cDNA 2810428F02 0.8 0.4 AK018383
gene
Tmprss4 Tmprss4 transmembrane protease, 11.7 2.0 BC021368
serine 4
Tnfrsf14 Tnfrsf14 tumor necrosis factor receptor 10.0 0.9 BC022125
superfamily, member 14
(herpesvirus entry mediator)
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 15.7 4.4 AI385482
superfamily, member 5
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 18.8 7.6 NM_011611
superfamily, member 5
Tnfrsf5 Tnfrsf5 tumor necrosis factor receptor 20.4 6.6 BB220422
superfamily, member 5
Tnfsf10 Tnfsf10 tumor necrosis factor (ligand) 5.1 0.4 NM_009425
superfamily, member 10
Top2b Top2b topoisomerase (DNA) II beta 1.8 0.6 BB166592
5430425C04Rik Tp53i5 RIKEN cDNA 5430425C04 3.5 1.2 AK017334
gene
— Trex1 Mus musculus adult female 6.3 2.9 AF140709
vagina cDNA, RIKEN full-
length enriched library,
clone: 9930022F21
product: similar to G PROTEIN
COUPLED RECEPTOR [Mus
musculus], full insert
sequence
Trim12 Trim12 tripartite motif protein 12 8.3 2.5 BM244351
Trim21 Trim21 tripartite motif protein 21 2.3 1.0 BC010580
Trim21 Trim21 tripartite motif protein 21 3.9 1.1 BC010580
Trim25 Trim25 tripartite motif protein 25 1.2 0.5 AI746456
Trim30 Trim30 tripartite motif protein 30 7.9 2.8 AF220015
9230105E10Rik Trim34 RIKEN cDNA 9230105E10 4.5 1.7 BI653857
gene
Gtl6 Trip12 gene trap locus 6 0.9 0.4 BG923744
E130308C19Rik Tspyl5 RIKEN cDNA E130308C19 1.6 0.4 AV332105
gene
Tuba8 Tuba8 tubulin, alpha 8 2.9 1.0 BB047533
Tyki Tyki thymidylate kinase family 1.9 0.5 AK004595
LPS-inducible member
C330001M22 Ubash3a hypothetical protein 3.1 1.3 BB397001
C330001M22
Ubd Ubd ubiquitin D 223.5 3.3 NM_023137
Ubce8 Ube2l6 ubiquitin-conjugating enzyme 8 8.7 1.2 BC008238
— Ubr1 Mus musculus transcribed 0.9 0.4 AV299235
sequence with weak
similarity to protein
pir: RGECDW (E. coli)
RGECDW transcription
activator of D-serine
dehydratase - Escherichia coli
Ugt8 Ugt8 UDP-glucuronosyltransferase 8 0.5 0.2 NM_011674
Upb1 Upb1 ureidopropionase, beta 0.4 0.1 NM_133995
Upp1 Upp1 uridine phosphorylase 1 8.2 2.1 NM_009477
Usp18 Usp18 ubiquitin specific protease 18 20.6 1.6 NM_011909
Wars Wars tryptophanyl-tRNA synthetase 2.4 0.9 BC003450
Wars Wars tryptophanyl-tRNA synthetase 2.7 0.8 BB785450
— Wld — 0.8 0.3 AF260924
Wrn Wrn Werner syndrome homolog 1.6 0.5 D86527
(human)
Xdh Xdh xanthine dehydrogenase 16.7 6.1 AV286265
— Ywhaq Mus musculus 16 days 1.3 0.5 AV024540
neonate thymus cDNA,
RIKEN full-length enriched
library, clone: A130046D12
product: 14-3-3 PROTEIN
TAU (14-3-3 PROTEIN
THETA), full insert sequence
Zbp1 Zbp1 Z-DNA binding protein 1 78.0 3.9 AK008179
Zbp1 Zbp1 Z-DNA binding protein 1 118.4 3.0 NM_021394
9430083K24Rik Zbtb5 RIKEN cDNA 9430083K24 1.3 0.6 AI267092
gene
Zc3hdc1 Zc3hdc1 zinc finger CCCH type 6.7 2.2 BM227980
domain containing 1
Zfp287 Zfp287 zinc finger protein 287 1.4 0.6 BI714160
AI839779 Zfp365 expressed sequence 0.5 0.2 AV327248
AI839779
Zfp386 Zfp386 zinc finger protein 386 1.8 0.8 NM_019565
(Kruppel-like)
4633401C23Rik Zfp84 RIKEN cDNA 4633401C23 1.3 0.6 AI465811
gene
Znfn1a3 Zfpn1a3 zinc finger protein, subfamily 4.4 1.9 BB202216
1A, 3 (Aiolos)
Zfr Zfr zinc finger RNA binding 2.6 1.0 BM119505
protein
— Mus musculus similar to 2- 2.1 0.9 BG070246
cell-stage, variable group,
member 3; 2-cell-stage,
variable group, member 1
(LOC236374), mRNA
— — 0.4 0.2 AK016021
— — 9.3 3.4 BB030365
— — 6.8 0.6 BB135602
— Mus musculus transcribed 0.7 0.2 BG071026
sequences
2210023K21Rik RIKEN cDNA 2210023K21 4.7 2.3 BI106821
gene
— — 3.6 1.5 AV340322
— Mus musculus transcribed 1.3 0.2 BB738659
sequences
— Mus musculus transcribed 0.3 0.1 BM054266
sequence with moderate
similarity to protein
ref: NP_114409.1 (H. sapiens)
hypothetical protein
MGC1314 similar to
fucosidase, alpha-L-1, tissue
[Homo sapiens]
Vcam1 vascular cell adhesion 19.2 8.8 BB250384
molecule 1
— Mus musculus anti-MUC1 1.5 0.5 AY058911
antibody SM3 Ig heavy chain
variable region mRNA, partial
cds
— Mus musculus LOC380741 1.6 0.5 BB323723
(LOC380741), mRNA
— Mus musculus cDNA clone 0.8 0.2 BB553937
IMAGE: 5151706, partial cds
— Mus musculus transcribed 1.5 0.1 BG862223
sequence with moderate
similarity to protein
pir: A47643 (M. musculus)
A47643 hypothetical protein -
mouse (fragment)
— Mus musculus adult male 1.6 0.7 BB022773
pituitary gland cDNA, RIKEN
full-length enriched library,
clone: 5330412J20
product: unknown EST, full
insert sequence
— — 1.4 0.3 BG065699
— Mus musculus 0 day neonate 1.5 0.7 AV251099
head cDNA, RIKEN full-length
enriched library,
clone: 4833429G05
product: unknown EST, full
insert sequence
— Mus musculus transcribed 1.1 0.5 BB378649
sequences
— Mus musculus similar to 1.9 0.7 AW123234
transmembrane protein
SHREW1 (LOC230959),
mRNA
— Mus musculus transcribed 0.8 0.3 AV370837
sequence with strong
similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
— — 0.6 0.2 AW319988
— Mus musculus 0 day neonate 0.5 0.2 BB750877
kidney cDNA, RIKEN full-
length enriched library,
clone: D630022F07
product: hypothetical protein,
full insert sequence
— Mus musculus cDNA clone 3.3 0.8 BC022776
MGC: 6071 IMAGE: 3492410,
complete cds
— Mouse non-productive mRNA 2.1 0.6 NM_011558
for T-cell receptor gamma V5-
J1-C1
— — 67.1 8.6 NM_022429
— Mus musculus transcribed 0.7 0.3 AW124641
sequence with strong
similarity to protein sp: P00722
(E. coli) BGAL_ECOLI Beta-
galactosidase (Lactase)
— Mus musculus transcribed 1.5 0.3 BB436326
sequence with moderate
similarity to protein
ref: NP_079184.1 (H. sapiens)
hypothetical protein FLJ12973
[Homo sapiens]
— Mus musculus transcribed 1.1 0.1 C77501
sequence with weak
similarity to protein
ref: NP_443092.1 (H. sapiens)
kruppel-like zinc finger protein
[Homo sapiens]
— Mus musculus transcribed 1.2 0.4 BB201888
sequence with moderate
similarity to protein
pir: R5HU35 (H. sapiens)
R5HU35 ribosomal protein
L35a - human
— Mus musculus transcribed 1.4 0.6 BB343967
sequences
Rnaset2 ribonuclease T2 1.7 0.8 AV101824
— Mus musculus diabetic 58.3 13.4 BM241271
nephropathy-related gene 1
mRNA, partial sequence
— Mus musculus transcribed 0.7 0.3 BE979870
sequences
— Mus musculus transcribed 5.0 1.2 BB534560
sequences
— Mus musculus transcribed 1.1 0.4 AV230978
sequences
Cxcl9 chemokine (C—X—C motif) 69.4 0.7 BI104444
ligand 9
— Mus musculus adult male 5.5 2.6 BB214834
aorta and vein cDNA, RIKEN
full-length enriched library,
clone: A530023D22
product: unclassifiable, full
insert sequence
Nalp6 NACHT, leucine rich repeat 0.6 0.2 BB071996
and PYD containing 6
— Mus musculus 9 days embryo 1.1 0.5 BB442202
whole body cDNA, RIKEN
full-length enriched library,
clone: D030030M01
product: unknown EST, full
insert sequence
— Mus musculus transcribed 61.7 0.4 AW111920
sequences
Clic5 chloride intracellular channel 5 0.9 0.2 BB236747
— Mus musculus adult male 10.9 1.4 BB645745
cortex cDNA, RIKEN full-
length enriched library,
clone: B530033B21
product: unknown EST, full
insert sequence
— — 1.5 0.1 BG297038
G1p2 interferon, alpha-inducible 16.7 3.0 AK019325
protein
— Mus musculus adult male 1.4 0.5 AV254764
testis cDNA, RIKEN full-
length enriched library,
clone: 4921513I01
product: unknown EST, full
insert sequence
— — 12.6 1.0 BB668084
— — 17.1 0.5 BG072508
— Mus musculus mRNA similar 5.1 0.7 BC020118
to interferon-inducible
GTPase (cDNA clone
MGC: 49532
IMAGE: 3495064), complete
cds
— Mus musculus adult male 0.9 0.1 BB428710
hippocampus cDNA, RIKEN
full-length enriched library,
clone: C630020O05
product: unknown EST, full
insert sequence
— Mus musculus 0 day neonate 1.5 0.7 BB313276
eyeball cDNA, RIKEN full-
length enriched library,
clone: E130009O20
product: unknown EST, full
insert sequence
— Mus musculus adult male 2.3 0.3 BB224338
aorta and vein cDNA, RIKEN
full-length enriched library,
clone: A530086D01
product: unknown EST, full
insert sequence
Hrasls3 HRAS like suppressor 3 21.7 1.0 BB404920
— — 4.6 0.8 AV340322
TABLE 4
GRIT expression in WT and GKO grafts
ISO D5 ISO D5 vs WT D5
Gene Symbol Gene Title Affymetrix vs NCBA ISO.GKO D5 vs NCBA
Iigp1 interferon inducible GTPase 1 27.5 8.1 45.7
Tgtp T-cell specific GTPase 16.6 8.1 28.4
Mpa2l macrophage activation 2 like 14.9 12.5 92.9
Gbp2 guanylate nucleotide binding protein 2 12.8 33.2 47.7
Gbp2 guanylate nucleotide binding protein 2 11.5 8.6 76.1
Iigp1 interferon inducible GTPase 1 11.2 7.4 20.4
Igtp interferon gamma induced GTPase 9.3 4.8 17.8
Cxcl10 chemokine (C—X—C motif) ligand 10 7.0 100.9
H2-DMb1 histocompatibility 2, class II, locus 6.5 2.6 11.3
Mb1
Gtpi-pending interferon-g induced GTPase 5.8 5.0 24.7
Ubd ubiquitin D 5.3 4.5 91.8
Psmb8 proteosome (prosome, macropain) 4.8 2.0 25.5
subunit, beta type 8 (large
multifunctional protease 7)
Stat1 signal transducer and activator of 3.9 3.3 11.7
transcription 1
Cxcl9 chemokine (C—X—C motif) ligand 9 3.7 14.7 99.8
Mpeg1 macrophage expressed gene 1 3.6 16.4
Psmb9 proteosome (prosome, macropain) 3.6 3.9 19.1
subunit, beta type 9 (large
multifunctional protease 2)
H2-DMb2 histocompatibility 2, class II, locus 3.4 6.3 13.3
Mb2
Psmb10 proteasome (prosome, macropain) 3.4 3.0 14.5
subunit, beta type 10
Ifi1 interferon inducible protein 1 3.1 3.9 8.2
Ifi47 interferon gamma inducible protein 3.1 3.7 21.4
Brd4 bromodomain containing 4 3.0 9.4
Ifit2 interferon-induced protein with 2.8 2.1 25.1
tetratricopeptide repeats 2
Pdcd1lg1 programmed cell death 1 ligand 1 2.7 4.5 29.6
Fgl2 fibrinogen-like protein 2 2.7 14.4
5033415K03Rik RIKEN cDNA 5033415K03 gene 2.7 17.5
Il18bp interleukin 18 binding protein 2.6 6.6 17.3
Stat1 signal transducer and activator of 2.6 7.1 7.7
transcription 1
H2-K histocompatibility 2, K region 2.6 4.7 9.0
Xdh xanthine dehydrogenase 2.6 11.7
Pigr polymeric immunoglobulin receptor 2.4 6.5
Parp14 poly (ADP-ribose) polymerase family, 2.4 2.7 11.4
member 14
Ccl5 chemokine (C-C motif) ligand 5 2.4 62.5 34.8
BE688358NCBI ESTs 2.2 3.5 16.0
5830458K16Rik RIKEN cDNA 5830458K16 gene 2.2 2.1 9.2
H2-T23 histocompatibility 2, T region locus 23 2.2 2.7 7.3
Arts1-pending type 1 tumor necrosis factor receptor 2.1 2.8
shedding aminopeptidase regulator
C2ta class II transactivator 2.1 3.8 7.7
Fabp7 fatty acid binding protein 7, brain 2.1 2.8
G1p2 interferon, alpha-inducible protein 2.1 8.0
Oasl2 2′-5′ oligoadenylate synthetase-like 2 1.9 14.7
Ms4a6b membrane-spanning 4-domains, 1.9 14.1
subfamily A, member 6B
Tapbp TAP binding protein 1.9 2.4 4.6
H2-Ab1 histocompatibility 2, class II antigen 1.9 5.0 5.9
A, beta 1
Ms4a4d membrane-spanning 4-domains, 1.8 3.8
subfamily A, member 4D
Zbp1 Z-DNA binding protein 1 1.8 2.9 12.2
C1s complement component 1, s 1.7 12.7
subcomponent
Lair1 leukocyte-associated Ig-like receptor 1 1.7 3.3
Ccl8 chemokine (C-C motif) ligand 8 1.6 3.1 3.1
Slamf8 Slamf8 1.6 3.4 15.4
H2-T10 histocompatibility 2, T region locus 10 1.6 3.5
Serpina10 hypothetical protein MGC25863 1.5 8.8
H2-K histocompatibility 2, K region 1.5 2.1 14.5
Irf7 interferon regulatory factor 7 1.4 6.4
C1r complement component 1, r 1.3 7.4
subcomponent
Ifit1 interferon-induced protein with 1.3 4.2 5.9
tetratricopeptide repeats 1
Ube1l Ube1l 1.2 4.2
Hrasls3 HRAS like suppressor 3 1.0 7.2
C2 complement component 2 (within H- 0.8 3.1
2S)
B2m Beta-2 microglobulin 0.8 5.5
TABLE 5
GRIT-like transcript expression in WT and GKO grafts
ISO D5 WT D5
vs ISO D5 vs vs
Gene Symbol Gene Title Affymetrix NCBA ISO.GKO NCBA
H2-Aa histocompatibility 2, class II antigen A, 5.1 3.8 10.8
alpha
Ms4a6d membrane-spanning 4-domains, 4.0 21.2
subfamily A, member 6D
Hist1h2ad histone 1, H2ad 3.4 32.4
H2-DMa histocompatibility 2, class II, locus DMa 3.4 3.6 11.3
Top2a topoisomerase (DNA) II alpha 3.4 8.5
H2-Aa histocompatibility 2, class II antigen A, 3.3 3.0 6.8
alpha
Ii la-associated invariant chain 3.1 3.5 5.5
Ctss cathepsin S 2.9 8.9
Tgfbi transforming growth factor, beta 2.9 17.3
induced, 68 kDa
Ccr5 chemokine (C-C motif) receptor 5 2.5 12.1
H2-Eb1 histocompatibility 2, class II antigen E 2.5 3.5 6.8
beta
C1qb complement component 1, q 2.3 8.7
subcomponent, beta polypeptide
Ifi27 interferon, alpha-inducible protein 27 2.2 3.2
Tgfbi transforming growth factor, beta 2.2 17.2
induced, 68 kDa
Coro1a coronin, actin binding protein 1A 2.1 35.2
C1qg complement component 1, q 2.1 8.8
subcomponent, gamma polypeptide
Coro1a coronin, actin binding protein 1A 2.0 55.3
Gzma granzyme A 1.9 2.7 4.6
Hck hemopoietic cell kinase 1.8 7.0
Ppicap peptidylprolyl isomerase C-associated 1.7 4.8
protein
Serping1 serine (or cysteine) proteinase inhibitor, 1.7 4.3
clade G, member 1
Itgax integrin alpha X 1.5 2.0 5.9
Was Wiskott-Aldrich syndrome homolog 1.4 5.9
(human)
Tmsb10 thymosin, beta 10 1.4 6.3
Tgfbi transforming growth factor, beta 1.4 14.0
induced, 68 kDa
Tmsb10 thymosin, beta 10 1.4 4.1
Epsti1 epithelial stromal interaction 1 (breast) 1.4 7.6
Ly6f lymphocyte antigen 6 complex, locus F 1.3 2.6
Ifitm3 interferon induced transmembrane 1.3 2.4
protein 3
Ifitm6 interferon induced transmembrane 1.3 2.6
protein 6
AW413625 expressed sequence AW413625 1.2 2.3 3.7
Tnfsf13b tumor necrosis factor (ligand) 1.2 2.8
superfamily, member 13b
AU020206 Mus musculus 3 days neonate thymus 1.2 5.1
cDNA, RIKEN full-length enriched
library, clone: A630040D01
Ifitm1 interferon induced transmembrane 1.2 2.4 2.5
protein 1
AI132321 Mus musculus 0 day neonate thymus 1.1 2.3 5.1
cDNA, RIKEN full-length enriched
library, clone: A430098J23
Gpm6b glycoprotein m6b 1.1 2.3
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.9 3.5
Emr4 EGF-like module containing, mucin-like, 0.9 3.0
hormone receptor-like sequence 4
Cxcl14 chemokine (C—X—C motif) ligand 14 0.8 3.0
Socs2 suppressor of cytokine signaling 2 0.8 2.2
9230117N10Rik RIKEN cDNA 9230117N10 gene 0.7 3.8
Cxcl14 chemokine (C—X—C motif) ligand 14 0.4 7.6
TABLE 6
Transcripts decreased in GKO D5 but not induced by rIFNγ
ISO D5 WT D5
vs ISO D5 vs vs
Gene Symbol Title_Affy NCBA ISO.GKO NCBA
5830443L24Rik RIKEN cDNA 5830443L24 gene 8.1 6.8 74.8
BC023105 cDNA sequence BC023105 7.5 20.0 10.9
Cxcl11 chemokine (C—X—C motif) ligand 11 5.8 2.5 70.4
Ifi202b interferon activated gene 202B 4.9 33.1
Ly86 lymphocyte antigen 86 3.4 12.9
Dnr12 Diabetic nephropathy-like protein (Dnr12) 3.1 3.2 20.4
mRNA, partial sequence
Ubce8 ubiquitin-conjugating enzyme 8 3.0 5.7
H2-D1 histocompatibility 2, D region locus 1 3.0 5.1 7.7
Trim34 tripartite motif protein 34 3.0 9.9
Aif1 allograft inflammatory factor 1 2.8 16.5
Klra2 killer cell lectin-like receptor, subfamily A, 2.7 7.3
member 2
Ptprcap protein tyrosine phosphatase, receptor 2.4 15.9
type, C polypeptide-associated protein
Ms4a4c membrane-spanning 4-domains, 2.4 3.2 14.0
subfamily A, member 4C
H28 histocompatibility 28 2.3 6.5
BC013712 cDNA sequence BC013712 2.2 2.4 7.1
Ms4a6c membrane-spanning 4-domains, 2.2 7.3
subfamily A, member 6C
H28 Histocompatibility 28 2.2 4.4
H2-Q1 histocompatibility 2, Q region locus 1 2.1 5.8 10.9
Tnfrsf5 tumor necrosis factor receptor 2.1 2.6 6.7
superfamily, member 5
Ifi205 interferon activated gene 205 2.1 3.6 25.4
Vcam1 vascular cell adhesion molecule 1 2.1 2.4 12.5
Sell selectin, lymphocyte 2.0 7.8
Tap2 transporter 2, ATP-binding cassette, sub- 1.9 2.9 7.4
family B (MDR/TAP)
Icsbp interferon concensus sequence binding 1.9 8.4
protein
Nmi N-myc (and STAT) interactor 1.9 5.4
Tnfsf10 tumor necrosis factor (ligand) 1.8 6.7
superfamily, member 10
Gbp4 guanylate nucleotide binding protein 4 1.8 12.6
Parp9 poly (ADP-ribose) polymerase family, 1.7 2.3 8.7
member 9
Ifi205 interferon activated gene 205 1.7 3.3 15.9
Casp1 caspase 1 1.7 6.6
Irf1 interferon regulatory factor 1 1.7 2.5 8.7
Igh-6 immunoglobulin heavy chain 6 (heavy 1.7 2.2 4.2
chain of IgM)
Ifit3 interferon-induced protein with 1.7 5.4
tetratricopeptide repeats 3
Casp11 caspase 11, apoptosis-related cysteine 1.7 8.4
protease (caspase 4 precursor)
Usp18 ubiquitin specific protease 18 1.7 8.5
Zc3hdc1 hypothetical protein 9930021O16 1.7 5.2
Samhd1 SAM domain and HD domain, 1 1.7 8.5
Fcrl3 Fc receptor-like 3 1.7 6.6
Oas1g 2′-5′ oligoadenylate synthetase 1G 1.6 3.3
Snx10 sorting nexin 10 1.6 14.0
0610037M15Rik RIKEN cDNA 0610037M15 gene 1.6 6.4
Ifi203 interferon activated gene 203 1.6 5.7
Stat2 signal transducer and activator of 1.6 4.4
transcription 2
Gzmk granzyme K 1.6 2.5
Ifi44 interferon-induced protein 44 1.5 4.2
IFNg interferon gamma 1.5 8.2
Slamf6 SLAM family member 6 1.5 2.2
H2-Q7 histocompatibility 2, Q region locus 7 1.5 3.3 11.2
Il12rb1 interleukin 12 receptor, beta 1 1.5 4.6
Ifi35 interferon-induced protein 35 1.5 4.2
Trim30 tripartite motif protein 30 1.5 4.4
Cybb cytochrome b-245, beta polypeptide 1.5 5.1
H2-M3 histocompatibility 2, M region locus 3 1.5 4.4
Glipr1 GLI pathogenesis-related 1 (glioma) 1.4 5.6
Slfn8 schlafen 8 1.4 3.0
Ifih1 interferon induced with helicase C 1.4 3.5
domain 1
Trim21 tripartite motif protein 21 1.4 3.0
Trim21 tripartite motif protein 21 1.4 2.3
Stat2 signal transducer and activator of 1.4 8.5
transcription 2
Parp3 poly (ADP-ribose) polymerase family, 1.3 4.4
member 3
2610042L04Rik RIKEN cDNA 2610042L04 gene 1.3 4.7
H2-T24 histocompatibility 2, T region locus 24 1.3 2.5
Slc41a2 solute carrier family 41, member 2 1.3 3.2
Sectm1 secreted and transmembrane 1 1.3 3.2
Gimap7 GTPase, IMAP family member 7 1.3 2.7 6.0
Cyp4v3 cytochrome P450, family 4, subfamily v, 1.3 2.0
polypeptide 3
Psme2 proteasome (prosome, macropain) 28 1.3 4.2
subunit, beta
Mx1 myxovirus (influenza virus) resistance 1 1.3 4.5
Dnase1l3 deoxyribonuclease 1-like 3 1.3 23.9
Ifi204 interferon activated gene 204 1.2 2.9 9.0
Tnfrsf5 tumor necrosis factor receptor 1.2 2.8 3.9
superfamily, member 5
Wars tryptophanyl-tRNA synthetase 1.2 3.5
Ly6c lymphocyte antigen 6 complex, locus C 1.2 2.2
Psme1 proteasome (prosome, macropain) 28 1.2 2.8
subunit, alpha
4930422C14 hypothetical protein 4930422C14 1.2 8.2
D11Lgp2e DNA segment, Chr 11, Lothar 1.2 16.8
Hennighausen 2, expressed
Samhd1 SAM domain and HD domain, 1 1.1 6.9
Dnase1l3 deoxyribonuclease 1-like 3 1.1 2.4
Gimap4 GTPase, IMAP family member 4 1.1 2.4
1110007F12Rik RIKEN cDNA 1110007F12 gene 1.1 3.9
H2-Oa histocompatibility 2, O region alpha locus 1.1 2.7
Pnp purine-nucleoside phosphorylase 1.1 2.4
Rbl1 retinoblastoma-like 1 (p107) 1.1 4.1
C920025E04Rik RIKEN cDNA C920025E04 gene 1.1 3.0
Cxcr3 chemokine (C—X—C motif) receptor 3 1.1 4.1
Klrk1 killer cell lectin-like receptor subfamily K, 1.1 3.9
member 1
Icsbp interferon concensus sequence binding 1.0 2.0 8.1
protein
Klra7 killer cell lectin-like receptor, subfamily A, 1.0 2.7
member 7
BC010462 cDNA sequence BC010462 1.0 2.9
Pbef-pending pre-B-cell colony-enhancing factor 1.0 2.1
Prkr protein kinase, interferon-inducible 1.0 3.0
double stranded RNA dependent
Wars tryptophanyl-tRNA synthetase 1.0 4.0
Asahl N-acylsphingosine amidohydrolase (acid 1.0 2.5
ceramidase)-like
Tlr3 toll-like receptor 3 1.0 2.4
1810054D07Rik RIKEN cDNA 1810054D07 gene 1.0 4.6
9530028C05 product: similar to 0.9 2.9
HISTOCOMPATIBILITY 2, CLASS II
ANTIGEN E BETA [Mus musculus], full
insert sequence.
Sell selectin, lymphocyte 0.9 3.7
Eif4e3 eukaryotic translation initiation factor 4E 0.9 3.1
member 3
2310016F22Rik RIKEN cDNA 2310016F22 gene 0.9 17.4
Irg1 immunoresponsive gene 1 0.9 34.6
Klrb1b killer cell lectin-like receptor subfamily B 0.9 2.7
member 1B
Tcf7 transcription factor 7, T-cell specific 0.9 10.1
Slamf7 SLAM family member 7 0.8 4.2
Ifi203 interferon activated gene 203 0.8 4.4
Cd3z CD3 antigen, zeta polypeptide 0.8 6.9
MGI: 1923551 FLN29 gene product 0.7 3.0
Trim34 tripartite motif protein 34 0.7 2.2
Upp uridine phosphorylase 0.6 6.5
Ngfr nerve growth factor receptor 0.5 9.9 2.3
Ifi203 interferon activated gene 203 0.3 23.6
TABLE 7
Injury-induced RITs in rejection
ISO ISO ISO WT WT WT WT WT
Gene Symbol Gene Title D21 D7 D5 D5 D7 D14 D21 D42 Genbank
1110028E10Rik RIKEN cDNA 1110028E10 gene 1.5 2.1 0.9 2.4 2.2 2.7 2.7 3.1 BB478892
1200016E24Rik RIKEN cDNA 1200016E24 gene 0.9 2.6 0.9 2.8 1.9 2.0 2.8 2.5 BF719154
1200016E24Rik RIKEN cDNA 1200016E24 gene 1.1 2.4 1.0 2.6 2.4 1.5 3.2 1.6 AU018141
2610042L04Rik RIKEN cDNA 2610042L04 gene 1.2 1.5 2.2 4.9 3.0 6.7 3.8 4.2 BM195235
9030408N13Rik RIKEN cDNA 9030408N13 gene 1.1 2.5 1.6 6.2 9.2 11.9 11.9 11.1 NM_025779
Abp1 amiloride binding protein 1 (amine oxidase, 0.8 3.1 0.9 4.0 2.6 10.0 8.0 5.0 BC021880
copper-containing)
Adamts1 a disintegrin-like and metalloprotease (reprolysin 1.1 2.9 1.5 4.2 2.2 5.4 4.0 4.7 D67076
type) with thrombospondin type 1 motif, 1
Adamts4 a disintegrin-like and metalloprotease (reprolysin 1.1 3.3 1.1 3.2 2.7 4.4 4.1 5.6 BB443585
type) with thrombospondin type 1 motif, 4
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.5 4.0 1.3 4.1 2.7 2.6 3.7 4.5 NM_009022
Anln anillin, actin binding protein (scraps homolog, 1.3 2.3 1.9 2.3 3.3 4.0 3.3 3.6 BI690018
Drosophila)
Arrb2 similar to Beta-arrestin 2 (Arrestin, beta 2) 0.9 2.1 1.0 5.2 8.6 11.4 10.8 9.8 BC016642
Asns asparagine synthetase 0.6 2.2 1.1 3.0 1.5 3.6 3.2 5.0 AV212753
Basp1 brain abundant, membrane attached signal 1.0 2.2 1.4 4.9 6.0 14.2 13.6 18.3 AK011545
protein 1
Bcl3 B-cell leukemia/lymphoma 3 1.7 3.6 1.8 7.2 8.0 4.8 7.0 4.7 NM_033601
Bcl6 B-cell leukemia/lymphoma 6 3.9 2.3 2.3 2.1 2.5 2.3 2.4 2.1 BB183854
Birc1b baculoviral IAP repeat-containing 1b 0.9 1.5 2.1 2.5 2.8 6.2 4.0 5.9 NM_010872
Bsf3-pending B-cell stimulating factor 3 0.6 2.0 2.1 2.1 2.2 3.5 5.0 3.3 BB825816
C1qa complement component 1, q subcomponent, 1.4 3.9 2.8 10.3 15.7 29.2 24.1 28.8 NM_007572
alpha polypeptide
C1qb complement component 1, q subcomponent, 2.3 2.2 2.0 3.4 5.0 10.2 6.6 7.7 AW227993
beta polypeptide
C79673 expressed sequence C79673 1.4 2.7 1.4 19.9 24.5 41.2 33.5 38.1 BG066664
Car13 carbonic anhydrase 13 0.6 2.1 1.5 4.2 2.2 4.5 3.7 3.3 NM_024495
Casp12 caspase 12 1.1 1.5 2.3 3.0 2.5 9.1 6.6 7.0 NM_009808
Ccl2 chemokine (C-C motif) ligand 2 1.1 2.9 1.2 7.4 7.5 10.7 9.3 10.5 AF065933
Ccl9 chemokine (C-C motif) ligand 9 0.7 2.4 1.2 3.1 5.0 6.4 11.4 12.1 NM_011338
Ccl9 chemokine (C-C motif) ligand 9 1.0 5.8 1.1 8.6 12.1 18.2 23.3 33.2 AF128196
Ccnb1 cyclin B1 1.0 2.7 2.4 9.9 6.7 8.6 5.6 5.5 X58708
Ccr2 chemokine (C-C) receptor 2 1.0 6.9 3.9 23.1 30.9 39.4 22.4 9.4 U47035
Ccr2 chemokine (C-C) receptor 2 1.9 3.2 3.6 13.4 17.7 17.5 14.1 7.8 NM_009915
Cd14 CD14 antigen 0.9 3.6 1.3 7.3 2.8 5.4 4.2 4.6 NM_009841
Cd44 CD44 antigen 1.1 3.7 2.1 9.8 14.3 29.6 28.9 25.0 BC005676
Cdc2a cell division cycle 2 homolog A (S. pombe) 0.3 3.4 1.3 5.1 5.0 5.3 3.6 3.7 NM_007659
Ch25h cholesterol 25-hydroxylase 1.0 2.1 1.4 6.7 8.0 12.3 6.7 12.7 NM_009890
Clca2 chloride channel calcium activated 2 0.7 2.2 2.2 2.2 1.4 3.7 2.1 5.3 AF108501
Clca2 chloride channel calcium activated 2 1.1 2.8 2.6 2.1 1.3 1.1 1.8 2.0 AF108501
Clecsf10 C-type (calcium dependent, carbohydrate 1.0 3.6 1.5 4.8 7.0 8.1 8.8 13.4 NM_020001
recognition domain) lectin, superfamily member 10
Clecsf10 C-type (calcium dependent, carbohydrate 1.0 4.0 1.3 5.0 6.8 16.5 10.4 19.5 AF240358
recognition domain) lectin, superfamily member 10
Clecsf6 C-type (calcium dependent, carbohydrate 1.1 4.3 3.8 4.7 7.0 12.8 14.3 14.4 NM_011999
recognition domain) lectin, superfamily member 6
Clecsf6 C-type (calcium dependent, carbohydrate 1.4 3.4 1.8 3.5 6.0 16.3 14.1 13.4 BC006623
recognition domain) lectin, superfamily member 6
Clecsf8 C-type (calcium dependent, carbohydrate 1.1 2.4 1.6 2.1 2.9 2.9 3.1 7.4 NM_010819
recognition domain) lectin, superfamily member 8
Clecsf9 C-type (calcium dependent, carbohydrate 1.0 4.3 2.8 16.2 18.5 12.2 7.5 11.6 BC003218
recognition domain) lectin, superfamily member 9
Col1a1 procollagen, type I, alpha 1 0.4 2.0 1.3 5.0 8.4 4.8 9.1 3.4 BI794771
Col1a1 procollagen, type I, alpha 1 2.0 6.8 1.9 11.3 26.7 18.9 31.4 17.8 U08020
Col1a2 procollagen, type I, alpha 2 1.0 2.4 1.5 4.3 6.3 8.9 7.0 7.6 BF227507
Col1a2 procollagen, type I, alpha 2 1.1 3.7 2.6 6.3 9.4 14.7 12.0 8.9 AW545978
Col3a1 procollagen, type III, alpha 1 1.1 4.8 2.6 5.4 6.8 15.5 8.9 11.0 BG968894
Col3a1 procollagen, type III, alpha 1 1.2 3.8 2.4 4.8 6.7 16.3 9.3 9.6 AW550625
Cp ceruloplasmin 0.5 2.6 1.6 2.8 1.2 2.9 2.6 1.6 BB531328
Cp ceruloplasmin 0.7 2.8 1.2 4.0 1.7 3.0 3.8 2.4 BB009037
Cp ceruloplasmin 0.9 3.1 1.5 3.5 2.9 3.5 5.2 2.2 NM_007752
Cp ceruloplasmin 0.9 3.1 1.7 4.4 1.8 3.0 4.1 2.3 NM_007752
Cp ceruloplasmin 1.0 2.9 1.7 3.8 1.6 3.1 3.6 2.1 NM_007752
Cpe carboxypeptidase E 1.3 2.5 2.5 2.2 1.3 1.3 1.6 0.9 BC010197
Crap cardiac responsive adriamycin protein 0.6 2.2 1.2 2.1 1.3 4.0 4.0 4.1 AK009959
Crap cardiac responsive adriamycin protein 0.7 3.5 1.8 3.3 1.6 7.4 6.3 9.3 NM_013468
Crlf1 cytokine receptor-like factor 1 1.9 5.2 1.2 10.6 12.2 11.5 13.4 18.1 NM_018827
Cspg2 chondroitin sulfate proteoglycan 2 0.7 2.2 1.3 4.0 3.7 11.3 5.2 11.1 BI692925
Cx3cr1 chemokine (C-X3-C) receptor 1 1.3 2.0 1.8 2.5 3.0 4.7 7.2 4.1 BC012653
Cxcl13 chemokine (C-X-C motif) ligand 13 1.2 2.9 1.3 3.6 2.3 1.3 2.0 1.8 NM_018866
Ddx3y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked 3.0 2.5 3.2 2.1 2.5 3.0 3.0 2.9 BB667072
Ddx3y DEAD (aspartate-glutamate-alanine-aspartate) 2.5 2.9 3.2 2.4 2.2 2.1 2.3 2.9 AJ007376
box polypeptide, Y chromosome
Ddx3y DEAD (aspartate-glutamate-alanine-aspartate) 3.1 3.5 3.3 3.1 3.1 4.1 3.2 3.8 AA210261
box polypeptide, Y chromosome
Dpysl3 dihydropyrimidinase-like 3 1.5 2.2 2.0 3.6 1.9 4.7 4.1 3.0 AV161550
Egr2 early growth response 2 0.6 2.0 1.3 3.7 4.6 6.2 7.7 6.6 X06746
Eif2s3y eukaryotic translation initiation factor 2, subunit 2.4 2.8 2.4 2.9 2.4 3.6 2.9 3.0 NM_012011
3, structural gene Y-linked
Emr1 EGF-like module containing, mucin-like, hormone 1.2 2.4 1.8 2.9 5.0 10.0 10.4 11.3 U66888
receptor-like sequence 1
Evi2 ecotropic viral integration site 2 1.1 2.2 2.3 5.8 7.7 12.8 9.4 8.9 NM_010161
F13a coagulation factor XIII, alpha subunit 1.2 2.5 1.7 2.8 2.9 3.7 3.2 9.3 NM_028784
Fbn1 fibrillin 1 1.1 2.3 2.0 2.5 2.8 5.6 4.1 5.4 NM_007993
Fcgr1 Fc receptor, IgG, high affinity I 1.2 2.2 2.0 7.0 9.7 23.7 11.0 21.4 AF143181
Fcgr3 Fc receptor, IgG, low affinity III 1.2 3.0 2.1 5.2 8.3 25.9 17.6 30.6 NM_010188
Fga fibrinogen, alpha polypeptide 1.0 3.9 0.8 7.3 2.7 1.1 0.6 0.7 BC005467
Fn1 fibronectin 1 1.1 2.3 1.6 2.1 3.1 7.6 7.6 7.8 BC004724
Fos FBJ osteosarcoma oncogene 0.9 2.1 1.2 5.3 5.6 9.6 5.7 7.6 AV026617
G7e-pending G7e protein 1.0 2.3 1.3 4.6 3.7 6.0 5.2 4.5 NM_033075
G7e-pending G7e protein 1.1 2.5 1.4 4.9 3.8 6.2 6.3 3.8 BC027314
Gm1549 gene model 1549, (NCBI) 1.1 1.2 2.2 2.6 2.2 2.7 1.1 2.6 AJ319753
Gp49b glycoprotein 49 B 1.4 5.2 2.6 10.1 13.9 28.0 17.8 32.0 U05264
Havcr1 hepatitis A virus cellular receptor 1 0.5 4.2 1.4 3.1 1.0 3.1 0.7 1.3 NM_134248
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.6 2.2 1.4 2.8 2.9 2.0 1.9 1.8 NM_013552
Igl-V1 immunoglobulin lambda chain, variable 1 3.7 4.6 2.1 3.3 3.3 36.1 40.9 32.9 AK008145
Igsf6 immunoglobulin superfamily, member 6 1.0 2.6 0.9 13.7 18.5 30.5 22.4 25.3 NM_030691
II1b interleukin 1 beta 1.2 3.7 1.1 2.1 2.2 5.1 3.5 5.2 BC011437
II1rn interleukin 1 receptor antagonist 0.9 3.1 1.7 4.7 3.9 11.8 5.5 12.5 M57525
Itgam integrin alpha M (CD11b) 1.2 3.8 2.1 5.5 7.9 11.0 8.8 10.8 NM_008401
Kif20a kinesin family member 20A 1.3 2.2 2.6 3.4 3.9 4.2 2.9 3.4 NM_009004
Kif22-ps kinesin family member 22, pseudogene 0.9 2.8 2.2 5.8 5.3 5.7 3.8 4.0 BB251322
Krt20 keratin 20 1.1 2.4 1.5 2.9 1.5 8.7 7.8 11.8 AF473907
Lcn2 lipocalin 2 1.0 15.4 2.2 27.6 11.8 40.9 35.8 53.0 X14607
Lcp1 lymphocyte cytosolic protein 1 0.9 2.3 1.5 14.1 15.8 20.0 15.2 18.3 BC022943
Lgals1 lectin, galactose binding, soluble 1 0.7 2.0 1.3 2.6 2.5 4.1 2.8 4.1 AI642438
Lgals1 lectin, galactose binding, soluble 1 0.9 2.0 1.1 3.0 2.8 3.6 3.1 3.1 NM_008495
Lif leukemia inhibitory factor 1.8 3.3 1.4 4.5 3.8 3.8 3.7 4.7 BB235045
Lox lysyl oxidase 0.6 5.8 2.3 8.0 6.3 22.5 12.5 31.2 M65143
Lox lysyl oxidase 0.8 2.5 1.3 4.1 3.1 9.8 6.8 12.9 NM_010728
Lrg1 leucine-rich alpha-2-glycoprotein 1.3 6.3 0.5 8.3 2.5 5.3 5.2 4.2 NM_029796
Lyzs lysozyme 1.4 7.7 2.7 22.8 26.8 39.5 43.7 22.1 AV058500
Lyzs lysozyme 1.5 4.9 1.8 13.6 19.0 25.2 21.3 25.9 AW208566
Lyzs lysozyme 1.6 7.9 2.7 19.0 20.9 38.2 19.1 32.7 AV066625
Mad2l1 MAD2 (mitotic arrest deficient, homolog)-like 1 0.9 2.2 1.6 4.6 3.8 4.5 2.8 2.8 NM_019499
(yeast)
Mcmd mini chromosome maintenance deficient 1.3 1.8 2.2 6.1 5.7 5.1 5.0 3.6 C80350
(S. cerevisiae)
Mcmd6 mini chromosome maintenance deficient 6 1.0 2.0 1.8 4.5 5.2 4.4 3.7 3.0 BB099487
(S. cerevisiae)
Mki67 antigen identified by monoclonal antibody Ki 67 0.8 2.6 2.2 9.8 11.3 7.8 8.8 3.7 X82786
Ms4a6d membrane-spanning 4-domains, subfamily A, 0.9 5.6 3.3 19.7 33.6 53.6 29.3 39.4 NM_026835
member 6D
Ms4a7 membrane-spanning 4-domains, subfamily A, 1.3 2.5 2.1 2.9 5.5 13.9 15.4 15.4 BC024402
member 7
Msn moesin 1.2 2.0 1.3 2.9 2.6 3.4 2.4 2.9 NM_010833
Ncf2 neutrophil cytosolic factor 2 1.3 2.1 2.0 4.6 5.7 13.6 9.3 11.5 NM_010877
Osmr oncostatin receptor 1.0 2.4 1.8 3.5 2.7 4.3 5.5 4.7 NM_011019
Pira6 paired-Ig-like receptor A6 1.2 2.4 2.2 6.9 9.6 16.9 9.2 8.4 NM_011093
Plac8 placenta-specific 8 0.8 2.0 1.3 7.5 7.1 6.5 5.9 5.0 AF263458
Plek pleckstrin 0.9 2.6 2.3 8.3 11.9 18.2 12.5 15.4 AF181829
Postn periostin, osteoblast specific factor 1.0 2.8 2.5 2.7 2.9 8.0 7.2 14.4 BI110565
Prc1 protein regulator of cytokinesis 1 0.7 2.4 3.1 5.4 4.3 6.0 3.7 3.6 BC005475
Ptgs2 prostaglandin-endoperoxide synthase 2 0.8 4.8 2.0 4.1 6.9 13.4 5.6 9.3 M88242
Rad51ap1 RAD51 associated protein 1 0.7 2.1 0.6 4.7 3.4 2.2 2.6 2.5 BC003738
Rarres2 retinoic acid receptor responder (tazarotene 2.2 2.4 1.3 3.6 2.7 7.4 5.9 6.5 AV012073
induced) 2
Rrm2 ribonucleotide reductase M2 0.9 2.3 1.4 5.1 3.4 3.9 2.4 3.2 NM_009104
Rrm2 ribonucleotide reductase M2 1.0 2.2 1.5 4.8 3.9 4.8 3.1 2.5 AV301324
Runx1 runt related transcription factor 1 0.9 2.3 1.3 3.8 3.2 7.5 7.8 8.8 BI696226
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.5 8.6 0.6 4.8 2.4 2.5 3.6 3.6 NM_013650
Saa1 serum amyloid A 1 1.0 5.8 1.7 27.3 3.7 6.3 3.2 1.3 NM_009117
Saa2 serum amyloid A 2 0.8 3.6 1.0 8.9 1.6 3.9 1.6 1.3 NM_011314
Saa3 serum amyloid A 3 0.8 2.4 0.9 5.5 4.2 3.6 2.1 4.7 NM_011315
Serpine1 serine (or cysteine) proteinase inhibitor, clade E, 1.1 5.6 0.9 6.5 10.0 23.4 11.0 32.2 NM_008871
member 1
Slc25a24 solute carrier family 25 (mitochondrial carrier, 0.8 2.0 1.5 2.3 2.2 5.4 3.5 4.1 BF578055
phosphate carrier), member 24
Smcy selected mouse cDNA on the Y 2.2 2.5 2.4 2.3 2.8 2.3 2.7 2.1 AF127244
Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B 1.0 2.5 1.6 4.9 3.4 8.8 5.5 5.7 NM_133888
Socs3 suppressor of cytokine signaling 3 0.7 6.8 2.5 16.9 12.9 19.2 13.5 18.9 BB241535
Socs3 suppressor of cytokine signaling 3 1.4 6.2 1.2 12.4 11.4 9.4 11.6 12.9 BB831725
Sprr2f small proline-rich protein 2F 0.8 5.8 1.4 2.4 1.1 46.4 26.1 22.6 NM_011472
Stk17b serine/threonine kinase 17b (apoptosis-inducing) 1.4 2.0 1.5 5.7 7.7 11.4 7.7 7.1 BG064688
Syncrip synaptotagmin binding, cytoplasmic RNA 3.1 3.6 2.7 4.0 3.4 4.7 3.2 4.0 BG920261
interacting protein
Tapbpl TAP binding protein-like 0.8 1.2 2.3 8.7 7.4 7.4 6.9 5.1 BC017613
Tgfbi transforming growth factor, beta induced, 68 kDa 1.0 2.5 2.1 4.6 4.6 8.0 6.0 5.3 BB532080
Tiarp-pending Tnfa-induced adipose-related protein 1.0 3.4 1.4 4.1 1.4 1.3 2.4 2.1 NM_054098
Timd2 T-cell immunoglobulin and mucin domain 1.8 2.7 2.4 2.5 1.6 1.6 0.5 1.0 BC025096
containing 2
Timd2 T-cell immunoglobulin and mucin domain 2.8 4.1 3.5 5.2 3.3 3.3 1.7 2.4 BC028829
containing 2
Timp1 tissue inhibitor of metalloproteinase 1 1.3 8.3 1.9 15.5 15.3 29.1 16.6 26.4 BC008107
Tnc tenascin C 0.3 3.3 1.4 2.4 3.3 4.4 5.5 10.4 NM_011607
Tnfrsf12a tumor necrosis factor receptor superfamily, 1.2 3.1 1.2 5.6 3.1 5.6 4.4 4.1 NM_013749
member 12a
Tnfrsf12a tumor necrosis factor receptor superfamily, 1.2 2.3 1.2 4.9 2.7 4.8 4.3 2.9 NM_013749
member 12a
Tpte transmembrane phosphatase with tensin 2.5 3.0 3.2 2.6 1.1 2.1 2.8 1.4 AJ311312
homology
Tubb6 tubulin, beta 6 0.8 5.8 1.0 13.5 12.0 13.0 11.2 21.8 NM_026473
Ugcg UDP-glucose ceramide glucosyltransferase 2.1 2.0 1.3 2.4 3.0 6.0 3.9 4.5 NM_011673
Uty ubiquitously transcribed tetratricopeptide repeat 2.2 2.7 2.5 2.2 1.5 1.6 1.2 1.7 NM_009484
gene, Y chromosome
Vcam1 vascular cell adhesion molecule 1 0.9 4.3 1.4 11.3 3.6 29.8 8.3 8.2 L08431
Vim vimentin 0.9 2.0 1.5 5.6 8.1 12.5 7.2 9.5 AV147875
Ywhag 3-monooxgenase/tryptophan 5-monooxgenase 2.4 2.1 0.3 2.0 2.2 2.7 1.9 2.2 NM_018871
activation protein, gamma polypeptide
TABLE 8
Functional annotation of injury-induced RIT
Gene ISO D7 vs ISO D5 vs WT D5 vs IFN-γ Tgf-β1
Symbol Gene Title Affymetrix NCBA NCBA NCBA regulated regulated
Timp1 tissue inhibitor of metalloproteinase 1 8.3 1.9 15.5 yes yes
Socs3 suppressor of cytokine signaling 3 6.8 2.5 16.9 yes yes
Col3a1 procollagen, type III, alpha 1 4.8 2.6 5.4 yes yes
II1b interleukin 1 beta 3.7 1.1 2.1 yes
Cd14 CD14 antigen 3.6 1.3 7.3 yes yes
Adamts4 a disintegrin-like and metalloprotease 3.3 1.1 3.2 yes
motif, 4
Fcgr3 Fc receptor, IgG, low affinity III 3.0 2.1 5.2 yes
Ccl2 chemokine (C-C motif) ligand 2 2.9 1.2 7.4 yes
Plek pleckstrin 2.6 2.3 8.3 yes
Cp ceruloplasmin 2.6 1.6 2.8 yes
Smpdl3b sphingomyelin phosphodiesterase, acid- 2.5 1.6 4.9 yes
like 3B
Lox lysyl oxidase 2.5 1.3 4.1 yes yes
Tgfbi transforming growth factor, beta induced, 2.5 2.1 4.6 yes yes
68 kDa
Col1a2 procollagen, type I, alpha 2 2.4 1.5 4.3 yes yes
Fbn1 fibrillin 1 2.3 2.0 2.5 yes
Fn1 fibronectin 1 2.3 1.6 2.1 yes yes
Fcgr1 Fc receptor, IgG, high affinity I 2.2 2.0 7.0 yes
Cspg2 chondroitin sulfate proteoglycan 2 2.2 1.3 4.0 yes yes
(Versican)
Arrb2 similar to Beta-arrestin 2 (Arrestin, beta 2) 2.1 1.0 5.2 yes
Fos FBJ osteosarcoma oncogene 2.1 1.2 5.3 yes
Ncf2 neutrophil cytosolic factor 2 2.1 2.0 4.6 yes
Col1a1 procollagen, type I, alpha 1 2.0 1.3 5.0 yes yes
Vim vimentin 2.0 1.5 5.6 yes yes
Casp12 caspase 12 1.5 2.3 3.0 yes
Postn periostin, osteoblast specific factor 2.8 2.5 2.7 yes
Bold letters indicate similar effects of cytokines, whereas italics indicate opposite effect.
Example 2 RITs and GRITs Identified Using a Second Algorithm A second, more refined algorithm was used to identify RITs and GRITs. This method involved RMA (robust multichip analysis).
Revised GRITs Algorithm
Statistical analysis: Raw microarray data was pre-processed using an RMA method (Bioconductor 1.7; R version 2.2). Microarrays for control and treatment groups were preprocessed separately for each mouse strain combination. After preprocessing, data sets were subjected to variance-based filtering, i.e., all probe sets that had an inter-quartile range of less than 0.5 (log 2 units), across all chips, were removed. Filtered data were then used for transcript selection. To be selected, a transcript was required to have a corrected p-value of 0.01 or lower, and had to be increased at least two-fold vs. appropriate controls. Corrected p-values (q-values) were calculated using the “limma” package (fdr adjustment method), which was uses an empirical Bayes method for assigning significance. The mean normalized value for replicate samples was used for further analysis. Finally, the data were imported into the GeneSpring™ 7.2 (Agilent, Palo Alto, Calif.) for further analyses and creation of transcript lists.
Selection and removal of transcripts associated with cytotoxic T cells: The previously defined CTL associated transcripts (CAT) selection was refined, using the transcriptome of CD8+ cells isolated from allo.CBA D5 into B6 allografts, and the CTL cell line transciptome. Microarray data were normalized (GCOS/GeneSpring) to normal B6 kidneys. Transcripts expressed in the CTL line and in CD8 cells isolated from day 5 allografts (P flags in both samples) were selected based on their ≧5-fold expression vs. normal NCBA kidney. This selection yielded 1849 probe sets. These CTL and CD8-associated transcripts (expanded CATs) were removed from all transcript lists prior to any analysis. An exception was made for Psmb8, Psmb9 and Ccl5 transcripts. Although prominently expressed in CTL, they also were expressed in rIFNg treated kidneys and/or a macrophage cell line.
Selection and removal of transcripts related to strain differences, somatically rearranged genes, and NK receptors: All probe sets showing differences in the basal signal (either 5-fold increased or decreased) between normal CBA, B6 and BALB/c kidneys were selected by the RMA-based method. These probe sets then were removed from the final transcript lists to reduce the influence of strain differences. Transcripts expressed by somatically rearranged genes, i.e., immunoglobulin genes, also were removed. In addition, transcripts for NK receptors of the Klr family were removed.
Development of the unique transcript lists: The term “transcript” refers to an mRNA identified by one or more numbered Affymetrix probe sets, while a “unique transcript” refers to an mRNA identified by only one probe set; these show the highest fold change of expression in the allografts at day 5 post-transplant. Certain probe sets representing the same transcript could appear in more than one list. These were arbitrarily kept only in the first list in which they appeared (e.g., tGRITs), and were eliminated from other lists (e.g., oGRITs, see below). All transcript name abbreviations use Entrez Gene nomenclature, which is available on the World Wide Web at ncbi.nlm.nih.gov/entrez).
IFN-γ-Dependent Rejection Induced Transcripts (GRITs)
The algorithms for transcript selection (applied after removing CATs and strain-differing transcripts) are shown in FIGS. 8A, 8B, and 8C. Fifty-eight transcripts were identified that were rIFN-γ-dependent in normal kidneys of CBA, B6 and BALB/c mice.
Transcripts increased at least 2-fold in day 5 allografts were termed “rejection-induced.” The inflammatory changes at day 5 did not fulfill the histologic criteria for rejection (tubulitis), but the patterns established at day 5 were highly conserved as rejection lesions evolved. 1319 unique rejection-induced transcripts were identified in D5 kidney allografts of B6, CBA, and BALB/c strains (FIG. 8B).
Rejection-induced transcripts that were IFN-γ-dependent in rejection were identified by studying allografts in IFN-γ-deficient (GKO) hosts. Kidney allografts from wild-type BALB/c into B6 (allo.BALB/c) were compared to BALB/c.GKO donors (H-2d) transplanted into B6.GKO (H-2b) recipients (allo.GKO D5). 443 rejection-induced transcripts were identified that were at least 2-fold (signal ratio) greater when IFN-γ was present than when it was absent. Of these, 55 transcripts (47 of which were unique transcripts) also were increased by rIFN-γ (FIG. 8C, Table 9), and thus were labeled true interferon gamma dependent rejection-induced transcripts (tGRITs). The remaining transcripts, 270 of which were unique transcripts, were not 2-fold induced by rIFN-γ in normal kidneys, but nevertheless were IFN-γ dependent in rejecting kidneys (FIG. 8C). To reflect their lower inducibility by rIFN-γ, these transcripts were termed “occult” GRITs (oGRITs; Table 10).
The “tGRIT” and “oGRIT” terms used in this example are equivalent to the “GRIT” term used in Example 1, i.e., the GRIT category includes tGRITs and oGRITs. On average, there was 70% overlap between the GRITs identified by the RMA method with the (GCOS/GeneSpring) method described in Example 1.
Injury and Repair Induced Transcripts (IRITs) Algorithm
Transcript selection: Samples preprocessing, normalization and data filtering was done using the RMA-based method. Data also were corrected for the tGRITs, oGRITs and new CTL associated transcripts before transcript selection. The following algorithm was used (FIG. 9): transcripts were required to be increased in at least one of the isografts day 1—day 21 (≧2-fold, p(fdr)=0.01, where “fdr” is the false discovery rate), and also in allo.CBA D5 (≧2-fold, p(fdr)=0.01). Transcripts satisfying these criteria were selected, and the overlapping 372 transcripts were termed injury and repair-induced transcripts (IRITs). The final list, corrected for polymorphisms, contained 303 unique (highest expression in allo.CBA D5 vs NCBA) IRITs (Table 11).
The IRITs listed in Table 11 show a substantial overlap with the RITs, the injury-induced RITs and the GRIT-like lists of transcripts established as described in Example 1. In addition, the IRITs recapitulate the Tgfb1 effect on the transcriptome of rejecting mouse kidneys, similarly to GRIT-like and injury-induced RITs.
TABLE 9
Refined true gamma interferon-dependent rejection-induced transcripts (tGRIT)
allo.CBA
NCBA D5 vs
Gene symbol Gene title raw NCBA GenBank
— — 144 25.0 BB734586
AI451557 expressed sequence AI451557 23 35.1 AV277444
AW112010 expressed sequence AW112010 144 46.8 BE688358
B2m beta-2 microglobulin 3304 4.8 AI099111
Bst2 bone marrow stromal cell antigen 2 134 12.9 BC008532
C1r complement component 1, r 86 13.3 NM_023143
subcomponent
C2 Complement component 2 (within H-2S), 315 4.4 AV227574
mRNA (cDNA clone MGC: 18582
IMAGE: 3992881)
Cxcl9 chemokine (C—X—C motif) ligand 9 81 129.5 NM_008599
D12Ertd647e DNA segment, Chr 12, ERATO Doi 647, 652 4.8 AW554405
expressed
Gbp2 guanylate nucleotide binding protein 2 95 133.2 NM_010260
Gbp4 guanylate nucleotide binding protein 4 68 54.4 NM_018734
H2-Aa /// H2- histocompatibility 2, class II antigen A, 926 10.2 AF119253
Ea alpha /// histocompatibility 2, class II
antigen E alpha
H2-Ab1 histocompatibility 2, class II antigen A, 351 18.8 M15848
beta 1
H2-D1 /// H2- histocompatibility 2, D region locus 1 /// 230 17.2 L23495
K1 /// H2-L /// histocompatibility 2, K1, K region ///
LOC56628 histocompatibility 2, D region /// MHC
(A.CA/J(H-2K-f) class I antigen
H2-DMa histocompatibility 2, class II, locus DMa 100 21.2 NM_010386
H2-DMb1 histocompatibility 2, class II, locus Mb1 58 19.2 NM_010387
H2-DMb1 /// histocompatibility 2, class II, locus Mb1 /// 179 17.7 NM_010388
H2-DMb2 histocompatibility 2, class II, locus Mb2
H2-DMb2 histocompatibility 2, class II, locus Mb2 81 25.3 NM_010388
H2-Eb1 histocompatibility 2, class II antigen E beta 679 9.7 NM_010382
H2-K1 histocompatibility 2, K1, K region 373 15.8 S70184
H2-T10 /// H2- histocompatibility 2, T region locus 10 /// 784 5.4 NM_010395
T22 /// H2-T9 histocompatibility 2, T region locus 22 ///
histocompatibility 2, T region locus 9
H2-T23 histocompatibility 2, T region locus 23 862 9.5 NM_010398
Herc5 hect domain and RLD 5 55 32.3 AW208668
Igtp interferon gamma induced GTPase 342 34.4 NM_018738
Ii la-associated invariant chain 1240 8.8 BC003476
Iigp1 interferon inducible GTPase 1 99 69.1 BM239828
Iigp2 interferon inducible GTPase 2 127 34.1 NM_019440
Il18bp interleukin 18 binding protein 116 19.6 AF110803
Irgm immunity-related GTPase family, M 485 14.5 NM_008326
Lgals3bp lectin, galactoside-binding, soluble, 3 360 5.3 NM_011150
binding protein
LOC56628 MHC (A.CA/J(H-2K-f) class I antigen 63 3.8 M58156
Mpa2l macrophage activation 2 like 50 174.1 BM241485
Mpeg1 macrophage expressed gene 1 217 18.8 L20315
Oasl2 2′-5′ oligoadenylate synthetase-like 2 56 22.8 BQ033138
Parp14 poly (ADP-ribose) polymerase family, 95 19.1 BC021340
member 14
Psmb10 proteasome (prosome, macropain) 251 16.2 NM_013640
subunit, beta type 10
Psmb8 proteosome (prosome, macropain) 205 29.6 NM_010724
subunit, beta type 8 (large multifunctional
peptidase 7)
Psmb9 proteosome (prosome, macropain) 142 25.3 NM_013585
subunit, beta type 9 (large multifunctional
peptidase 2)
Psme1 proteasome (prosome, macropain) 28 1008 4.5 NM_011189
subunit, alpha
Serpina10 serine (or cysteine) peptidase inhibitor, 95 44.9 BC018416
clade A (alpha-1 antiproteinase,
antitrypsin), member 10
Serping1 serine (or cysteine) peptidase inhibitor, 721 7.0 NM_009776
clade G, member 1
Stat1 signal transducer and activator of 350 23.9 AW214029
transcription 1
Tap1 transporter 1, ATP-binding cassette, sub- 60 24.0 AW048052
family B (MDR/TAP)
Tapbp TAP binding protein 962 6.1 AF043943
Tgtp T-cell specific GTPase 481 32.6 NM_011579
Ubd ubiquitin D 47 255.8 NM_023137
Xdh xanthine dehydrogenase 53 16.7 AV286265
TABLE 10
Refined occult gamma interferon-dependent rejection-induced transcripts (oGRIT)
NCBA allo.CBA D5
Gene Symbol Gene Title Raw vs NCBA GenBank
1-Mar membrane-associated ring finger 21 7.4 BB134696
(C3HC4) 1
6-Sep septin 6 81 4.0 BC010489
— — 307 2.7 AV340322
— — 261 3.4 AV340322
— — 50 2.9 BG695418
— — 51 15.6 BB668084
— Transcribed locus 28 3.2 BB376947
— Transcribed locus 52 60.2 AW111920
— Transcribed locus 12 3.1 BG144448
— — 15 2.9 BQ266693
— Transcribed locus, weakly similar to 17 5.4 BB740904
NP_795929.1 hypothetical protein
LOC319587 [Mus musculus]
— 16 days neonate thymus cDNA, RIKEN 113 5.8 BI653857
full-length enriched library,
clone: A130050C20
product: hypothetical Butyrophylin-
like/SPIa/RYanodine receptor
SPRY/B302, (SPRY)-like containing
protein, full insert sequence
— — 15 4.9 BG072508
— — 32 11.8 BB558917
0610025L06Rik RIKEN cDNA 0610025L06 gene 183 3.9 AK012581
0610033I05Rik RIKEN cDNA 0610033I05 gene 137 3.5 BC003333
1110007F12Rik RIKEN cDNA 1110007F12 gene 422 3.7 BC020080
1110038F14Rik RIKEN cDNA 1110038F14 gene 187 2.0 NM_054099
1500004A08Rik RIKEN cDNA 1500004A08 gene 109 2.5 BB030508
1810009K13Rik RIKEN cDNA 1810009K13 gene 136 2.1 AK007407
1810054D07Rik RIKEN cDNA 1810054D07 gene 15 4.1 BB397062
2310016F22Rik /// RIKEN cDNA 2310016F22 gene /// 39 11.0 BC020489
LOC223672 hypothetical protein LOC223672
2700019D07Rik RIKEN cDNA 2700019D07 gene 160 2.7 BM937429
2810417H13Rik RIKEN cDNA 2810417H13 gene 14 16.9 AK017673
4933430F08Rik RIKEN cDNA 4933430F08 gene 128 6.4 AK016990
5133401N09Rik RIKEN cDNA 5133401N09 gene 464 2.5 BC026742
5830443L24Rik RIKEN cDNA 5830443L24 gene 49 115.5 NM_029509
5830458K16Rik RIKEN cDNA 5830458K16 gene 149 13.3 BC024872
9130017N09Rik RIKEN cDNA 9130017N09 gene 163 2.6 BQ030875
9330175E14Rik RIKEN cDNA 9330175E14 gene 27 2.7 BB082472
9530028C05 hypothetical protein 9530028C05 80 5.0 BQ175154
9830147J24Rik RIKEN cDNA 9830147J24 gene 46 56.7 BM241271
A430107D22Rik RIKEN cDNA A430107D22 gene 60 3.4 AV312663
A630077B13Rik RIKEN cDNA A630077B13 gene 17 92.0 BB239429
AB124611 cDNA sequence AB124611 33 10.5 BM246462
Adar RNA adenosine deaminase 1 (Adar) 30 3.3 BB308291
mRNA, complete cds, alternatively
spliced
AI447904 expressed sequence AI447904 12 44.0 BM241008
AI447904 /// expressed sequence AI447904 /// 32 29.7 BM241008
BC094916 cDNA sequence BC094916
AI451617 expressed sequence AI451617 19 11.2 BM241342
AI480535 expressed sequence AI480535 517 2.5 BQ176847
AI607873 expressed sequence AI607873 10 11.6 AI607873
AI661384 expressed sequence AI661384 11 5.3 BB034038
Aif1 allograft inflammatory factor 1 47 23.0 NM_019467
Ak7 adenylate kinase 7 231 3.0 AV256298
Akt3 thymoma viral proto-oncogene 3 74 3.5 BB521695
Arid5a AT rich interactive domain 5A (Mrf1 74 3.0 BC027152
like)
Asahl N-acylsphingosine amidohydrolase 140 6.8 BI106821
(acid ceramidase)-like
Atp8a1 ATPase, aminophospholipid transporter 67 6.0 AW610650
(APLT), class I, type 8A, member 1
AU020206 expressed sequence AU020206 69 12.1 BI151331
B230217C12Rik RIKEN cDNA B230217C12 gene 30 3.3 BB376573
BC006779 cDNA sequence BC006779 95 4.9 BE853170
BC010462 cDNA sequence BC010462 84 4.1 BC010462
BC013672 cDNA sequence BC013672 12 3.8 BC013672
BC013712 cDNA sequence BC013712 97 9.6 BB262491
BC023105 cDNA sequence BC023105 20 42.8 BC023105
BC027057 cDNA sequence BC027057 24 3.9 BB040051
Btla B and T lymphocyte associated 29 8.8 BM240873
C1s complement component 1, s 156 13.0 BC022123
subcomponent
C2ta class II transactivator 29 9.5 AF042158
C2ta class II transactivator 40 6.7 AF042158
C4 complement component 4 (within H-2S) 367 6.9 NM_009780
Card4 caspase recruitment domain 4 132 3.0 BB138330
Casp1 caspase 1 44 9.6 BC008152
Casp11 caspase 11, apoptosis-related cysteine 39 13.6 NM_007609
peptidase
Casp12 caspase 12 33 9.5 NM_009808
Casp7 caspase 7 140 4.0 NM_007611
Ccl19 chemokine (C-C motif) ligand 19 305 2.1 NM_011888
Ccl5 chemokine (C-C motif) ligand 5 75 36.7 NM_013653
Ccl8 chemokine (C-C motif) ligand 8 36 22.0 NM_021443
Ccr5 chemokine (C-C motif) receptor 5 24 11.5 X94151
Ccr9 chemokine (C-C motif) receptor 9 16 2.4 AJ131357
Ccrl2 chemokine (C-C motif) receptor-like 2 73 2.7 AJ318863
Cd2 CD2 antigen 26 8.4 NM_013486
Cd274 CD274 antigen 50 27.3 NM_021893
Cd28 CD28 antigen 13 21.6 NM_007642
Cd40 CD40 antigen 70 7.1 BB220422
Cd48 CD48 antigen 29 25.5 BE634960
Cd5 CD5 antigen 21 10.0 NM_007650
Cd6 CD6 antigen 57 3.0 U12434
Cd69 CD69 antigen 12 6.4 AK017979
Cd72 CD72 antigen 40 5.7 BC003824
Cd86 CD86 antigen 27 8.8 NM_019388
Cerkl ceramide kinase-like 34 13.8 BB205589
Clec2d C-type lectin domain family 2, member d 211 3.1 NM_053109
Csprs component of Sp100-rs 84 2.8 BB148221
Ctsc cathepsin C 13 9.7 BM237633
Ctsw cathepsin W 49 11.9 NM_009985
Cxcl10 chemokine (C—X—C motif) ligand 10 69 95.2 NM_021274
Cxcl11 chemokine (C—X—C motif) ligand 11 37 169.3 NM_019494
Cxcl16 chemokine (C—X—C motif) ligand 16 652 3.3 BC019961
Cxcl16 /// chemokine (C—X—C motif) ligand 16 /// 99 2.9 AI662455
LOC574428 zinc finger, MYND domain containing
15
Cxcr3 chemokine (C—X—C motif) receptor 3 60 8.2 NM_009910
Cxcr6 chemokine (C—X—C motif) receptor 6 28 15.4 AF301018
Cybb cytochrome b-245, beta polypeptide 52 21.8 NM_007807
Cyp4v3 cytochrome P450, family 4, subfamily 49 3.5 NM_133969
v, polypeptide 3
D11Ertd759e DNA segment, Chr 11, ERATO Doi 363 5.0 AW556558
759, expressed
D11Lgp2e DNA segment, Chr 11, Lothar 42 6.8 AF316999
Hennighausen 2, expressed
D14Ertd668e DNA segment, Chr 14, ERATO Doi 115 6.5 AV280841
668, expressed
Dck deoxycytidine kinase 13 7.8 NM_007832
Dnase1l3 deoxyribonuclease 1-like 3 28 6.3 BC012671
Dtx3l deltex 3-like (Drosophila) 136 12.0 AV327407
Eif2ak2 eukaryotic translation initiation factor 2- 81 3.2 BE911144
alpha kinase 2
Eif4e3 eukaryotic translation initiation factor 162 5.2 BC027014
4E member 3
Enc1 ectodermal-neural cortex 1 77 4.4 BM120053
Epsti1 epithelial stromal interaction 1 (breast) 37 20.0 BF020640
Evl Ena-vasodilator stimulated 45 8.3 AW553781
phosphoprotein
Fabp7 fatty acid binding protein 7, brain 259 6.6 NM_021272
Fas Fas (TNF receptor superfamily 85 3.2 NM_007987
member)
Fbxo39 F-box protein 39 168 11.3 BB645745
Fbxo6b F-box only protein 6b 301 2.8 NM_015797
Fbxw17 F-box and WD-40 domain protein 17 181 3.3 AV016303
Fcgr1 Fc receptor, IgG, high affinity I 35 20.5 AF143181
Fcgr1 Fc receptor, IgG, high affinity I 80 2.6 BB075261
Fcgr3a Fc fragment of IgG, low affinity IIIa, 47 22.5 BC027310
receptor
Fgd2 FYVE, RhoGEF and PH domain 66 2.2 NM_013710
containing 2
Fgf13 fibroblast growth factor 13 18 2.0 AF020737
Fgl2 fibrinogen-like protein 2 31 45.9 BF136544
Fyb FYN binding protein (Fyb), mRNA 31 4.2 BE853428
G1p2 interferon, alpha-inducible protein 40 17.2 AK019325
Gbp1 guanylate nucleotide binding protein 1 22 23.9 NM_010259
Gdap10 ganglioside-induced differentiation- 99 4.8 NM_010268
associated-protein 10
Gimap3 GTPase, IMAP family member 3 91 6.2 NM_031247
Gimap4 GTPase, IMAP family member 4 677 3.6 BC005577
Gimap7 GTPase, IMAP family member 7 28 12.3 BC026200
Gja4 gap junction membrane channel protein 86 2.0 AF216832
alpha 4
Gm376 PREDICTED: similar to putative 9 3.7 BB241847
purinergic receptor FKSG79 [Mus
musculus], mRNA sequence
Gpr18 G protein-coupled receptor 18 32 10.8 BG145550
Gsdmdc1 gasdermin domain containing 1 119 4.1 AK007710
Gvin1 GTPase, very large interferon inducible 1 98 43.2 BM243571
Gzmk granzyme K 23 6.2 AB032200
H28 histocompatibility 28 106 10.0 BC024930
H2-D1 histocompatibility 2, D region locus 1 43 10.0 M33151
H2-M3 histocompatibility 2, M region locus 3 106 6.5 NM_013819
H2-Oa histocompatibility 2, O region alpha 43 4.6 NM_008206
locus
H2-Q5 histocompatibility 2, Q region locus 5 40 5.5 NM_010393
H2-Q8 histocompatibility 2, Q region locus 8 23 2.2 AK013097
H2-T24 histocompatibility 2, T region locus 24 46 3.6 L22338
Hck hemopoietic cell kinase 41 18.7 NM_010407
Hk3 hexokinase 3 84 2.9 BB324660
Hpse Heparanase (Hpse), mRNA 42 5.6 BG094050
Hrasls3 HRAS like suppressor 3 166 20.1 BB404920
Ibrdc3 IBR domain containing 3 133 8.4 AK015966
Icos inducible T-cell co-stimulator 21 5.4 AB023132
Ifi202b interferon activated gene 202B 27 64.8 AV229143
Ifi203 /// Ifi204 /// interferon activated gene 203 /// 11 82.9 AI481797
Ifi205 /// Mnda /// interferon activated gene 204 ///
LOC545386 interferon activated gene 205 ///
myeloid cell nuclear differentiation
antigen /// similar to Interferon-
activatable protein 205 (IFI-205) (D3
protein)
Ifi203 /// interferon activated gene 203 /// similar 64 10.1 BC008167
LOC547362 to interferon-inducible protein 203
Ifi204 /// Mnda interferon activated gene 204 /// 13 13.7 NM_008329
myeloid cell nuclear differentiation
antigen
Ifi205 /// Mnda interferon activated gene 205 /// 29 92.9 AI481797
myeloid cell nuclear differentiation
antigen
Ifi27 interferon, alpha-inducible protein 27 119 7.4 AY090098
Ifi35 interferon-induced protein 35 406 6.6 AW986054
Ifi44 interferon-induced protein 44 121 8.0 BB329808
Ifi47 interferon gamma inducible protein 47 196 40.5 NM_008330
Ifih1 interferon induced with helicase C 181 5.5 AY075132
domain 1
Ifit1 interferon-induced protein with 29 23.3 NM_008331
tetratricopeptide repeats 1
Ifit2 interferon-induced protein with 125 32.5 NM_008332
tetratricopeptide repeats 2
Ifit3 interferon-induced protein with 317 6.6 NM_010501
tetratricopeptide repeats 3
IFNg interferon gamma 25 22.9 K00083
Il10ra interleukin 10 receptor, alpha 29 4.8 NM_008348
Il12rb1 interleukin 12 receptor, beta 1 32 2.4 NM_008353
Il16 interleukin 16 88 2.6 BC026894
Il18 interleukin 18 141 2.6 NM_008360
Il2rb interleukin 2 receptor, beta chain 55 4.7 M28052
Il2rb interleukin 2 receptor, beta chain 27 8.6 M28052
Il2rg interleukin 2 receptor, gamma chain 121 18.6 L20048
Indo indoleamine-pyrrole 2,3 dioxygenase 21 2.6 NM_008324
Inpp1 inositol polyphosphate-1-phosphatase 63 3.0 NM_008384
Irf1 interferon regulatory factor 1 312 14.9 NM_008390
Irf7 interferon regulatory factor 7 118 6.4 NM_016850
Irf8 interferon regulatory factor 8 157 12.0 BG069095
Irg1 immunoresponsive gene 1 31 17.9 L38281
Isg20 interferon-stimulated protein 51 5.4 BC022751
Itgal integrin alpha L 41 2.9 AF065902
Itgal integrin alpha L 41 20.3 BI554446
Lair1 leukocyte-associated Ig-like receptor 1 29 7.8 AK017222
Lck lymphocyte protein tyrosine kinase 40 25.5 BC011474
LOC432460 similar to RIKEN cDNA 6330442E10 23 2.7 BB302103
gene
LOC544986 /// similar to hypothetical protein 47 7.3 BM195235
LOC544991 /// LOC67055 /// similar to hypothetical
LOC544997 /// protein LOC67055 /// similar to
B930046C15Rik hypothetical protein LOC67055 ///
/// LOC545001 /// RIKEN cDNA B930046C15 gene ///
LOC545005 /// hypothetical protein LOC545001 ///
LOC545007 /// hypothetical protein LOC545005 ///
LOC545008 /// hypothetical protein LOC545007 ///
2610042L04Rik /// similar to hypothetical protein
LOC545017 LOC67055 /// RIKEN cDNA
2610042L04 gene /// similar to
hypothetical protein LOC67055
LOC547214 similar to G protein coupled receptor 14 3.8 AF140709
Lst1 leukocyte specific transcript 1 125 8.9 U72644
Ly6c lymphocyte antigen 6 complex, locus C 1041 3.9 NM_010741
Ly6i lymphocyte antigen 6 complex, locus I 125 11.2 AF232024
Ly75 lymphocyte antigen 75 12 3.7 NM_013825
MGI: 1933403 type 1 tumor necrosis factor receptor 154 4.7 NM_030711
shedding aminopeptidase regulator
Mlkl mixed lineage kinase domain-like 37 14.3 AK018636
Ms4a4b membrane-spanning 4-domains, 18 92.0 BB199001
subfamily A, member 4B
Ms4a4c membrane-spanning 4-domains, 11 48.3 NM_022429
subfamily A, member 4C
Ms4a4d membrane-spanning 4-domains, 31 15.2 NM_025658
subfamily A, member 4D
Ms4a6b membrane-spanning 4-domains, 30 70.6 NM_027209
subfamily A, member 6B
Ms4a6c membrane-spanning 4-domains, 106 14.0 AF237910
subfamily A, member 6C
Mx1 myxovirus (influenza virus) resistance 1 22 3.8 M21039
Myb myeloblastosis oncogene 10 2.9 BC011513
Nkg7 natural killer cell group 7 sequence 57 23.5 NM_024253
Nmi N-myc (and STAT) interactor 267 7.2 BC002019
Oas1a 2′-5′ oligoadenylate synthetase 1A 119 8.7 BC018470
Oasl1 2′-5′ oligoadenylate synthetase-like 1 48 8.4 AB067533
P2ry13 purinergic receptor P2Y, G-protein 35 3.4 AK008013
coupled 13
P2ry14 purinergic receptor P2Y, G-protein 57 3.1 AF177211
coupled, 14
Parp11 poly (ADP-ribose) polymerase family, 155 2.7 BB026163
member 11
Parp12 poly (ADP-ribose) polymerase family, 161 8.6 BM227980
member 12
Parp3 poly (ADP-ribose) polymerase family, 141 4.4 BC014870
member 3
Parp9 poly (ADP-ribose) polymerase family, 179 12.0 NM_030253
member 9
Parvg parvin, gamma 41 2.5 NM_022321
Pbef1 pre-B-cell colony-enhancing factor 1 823 3.1 AW989410
Pigr polymeric immunoglobulin receptor 857 3.7 NM_011082
Plac8 placenta-specific 8 208 21.7 AF263458
Pml promyelocytic leukemia 58 2.7 BB667149
Pnp purine-nucleoside phosphorylase 2805 2.1 BC003788
Pnp /// purine-nucleoside phosphorylase /// 1262 2.7 AK008143
LOC545044 similar to purine-nucleoside
phosphorylase
Ppa1 pyrophosphatase (inorganic) 1 609 3.6 NM_026438
Ppfia4 protein tyrosine phosphatase, receptor 35 2.8 AK003571
type, f polypeptide (PTPRF), interacting
protein (liprin), alpha 4
Prkcq protein kinase C, theta 118 3.0 AB062122
Procr protein C receptor, endothelial 101 4.5 NM_011171
Psme2 proteasome (prosome, macropain) 28 709 6.2 NM_011190
subunit, beta
Ptprcap protein tyrosine phosphatase, receptor 141 3.7 NM_016933
type, C polypeptide-associated protein
Rasa4 RAS p21 protein activator 4 32 2.3 NM_133914
Rbl1 retinoblastoma-like 1 (p107) 82 8.2 U27177
Rgs1 regulator of G-protein signaling 1 45 8.0 NM_015811
Rnase6 ribonuclease, RNase A family, 6 31 4.8 AW825994
Rsad2 radical S-adenosyl methionine domain 433 3.0 BB132493
containing 2
Samhd1 SAM domain and HD domain, 1 119 18.7 NM_018851
Scap1 src family associated phosphoprotein 1 39 2.9 BG075562
Sectm1 secreted and transmembrane 1 1125 4.0 AI481997
Serpina3g serine (or cysteine) peptidase inhibitor, 44 98.9 BC002065
clade A, member 3G
Serpinb9 serine (or cysteine) peptidase inhibitor, 390 6.5 NM_009256
clade B, member 9
Sh2d1a SH2 domain protein 1A 12 3.5 NM_011364
Slamf6 SLAM family member 6 19 12.8 AF248636
Slamf7 SLAM family member 7 23 4.2 AK016183
Slamf8 SLAM family member 8 18 45.2 BC024587
Slc28a2 /// solute carrier family 28 (sodium- 14 8.5 NM_021520
LOC381417 coupled nucleoside transporter),
member 2 /// similar to solute carrier
family 28 (sodium-coupled nucleoside
transporter), member 2
Slc2a6 solute carrier family 2 (facilitated 33 3.0 BB196807
glucose transporter), member 6
Slfn1 schlafen 1 24 17.5 NM_011407
Slfn8 schlafen 8 55 4.3 BC024709
Snx10 sorting nexin 10 103 17.3 AK010399
Socs1 suppressor of cytokine signaling 1 45 5.3 AB000710
Sp100 nuclear antigen Sp100 81 2.7 U83636
Stat2 signal transducer and activator of 50 5.0 AF088862
transcription 2
Tap2 transporter 2, ATP-binding cassette, 171 11.3 BE691515
sub-family B (MDR/TAP)
Tapbpl TAP binding protein-like 21 3.6 BC017613
Tapbpl TAP binding protein-like 131 5.7 BC017613
Tbc1d10c TBC1 domain family, member 10c 58 6.8 AV060417
Tbx21 T-box21 18 5.5 NM_019507
Tcf7 transcription factor 7, T-cell specific 32 9.3 AI323642
Tinagl tubulointerstitial nephritis antigen-like 500 2.4 BC005738
Tlr3 toll-like receptor 3 43 2.6 NM_126166
Tmprss4 transmembrane protease, serine 4 65 3.2 BC021368
Tnfrsf14 tumor necrosis factor receptor 43 3.2 BC022125
superfamily, member 14 (herpesvirus
entry mediator)
Tnfrsf7 tumor necrosis factor receptor 23 5.5 L24495
superfamily, member 7
Tnfsf10 tumor necrosis factor (ligand) 118 5.9 NM_009425
superfamily, member 10
Tor3a torsin family 3, member A 63 4.8 AK009693
Tox thymocyte selection-associated HMG 22 5.3 BB547854
box gene
Tpst1 protein-tyrosine sulfotransferase 1 132 2.9 NM_013837
Trafd1 TRAF type zinc finger domain 237 4.3 AK003586
containing 1
Treml4 triggering receptor expressed on 13 6.2 BB740529
myeloid cells-like 4
Trex1 three prime repair exonuclease 1 157 3.8 NM_011637
Trim21 tripartite motif protein 21 125 5.1 BC010580
Trim30 tripartite motif protein 30 48 11.5 AF220015
Trim34 /// tripartite motif protein 34 /// similar to 29 9.7 AF220142
LOC434218 tripartite motif protein TRIM34 alpha
Tuba8 tubulin, alpha 8 37 3.0 NM_017379
Tyki thymidylate kinase family LPS-inducible 131 3.1 AK004595
member
Ube1l ubiquitin-activating enzyme E1-like 61 6.2 AK004894
Ube2l6 ubiquitin-conjugating enzyme E2L 6 50 7.8 BC008238
Unc93b1 unc-93 homolog B1 (C. elegans) 368 1.9 BC018388
Upp1 uridine phosphorylase 1 135 10.3 NM_009477
Usp18 ubiquitin specific peptidase 18 50 29.5 NM_011909
Vcam1 vascular cell adhesion molecule 1 112 45.1 BB250384
Wars tryptophanyl-tRNA synthetase 322 3.3 AI528863
Zap70 zeta-chain (TCR) associated protein 43 6.4 NM_009539
kinase
Zbp1 Z-DNA binding protein 1 75 23.3 AK008179
Zc3h12d zinc finger CCCH-type containing 12D 19 6.7 BB508669
Zfpn1a3 zinc finger protein, subfamily 1A, 3 16 14.6 BB151746
(Aiolos)
TABLE 11
Refined injury and repair-induced transcripts (IRIT)
allo.CBA D5
Gene Symbol Gene Title vs NCBA Genbank
— Transcribed locus 2.8 AA266723
1110006O17Rik RIKEN cDNA 1110006O17 gene 4.6 BB736636
1200008O12Rik RIKEN cDNA 1200008O12 gene 12.5 AK004655
1200016E24Rik RIKEN cDNA 1200016E24 gene 4.5 BF719154
1300002K09Rik RIKEN cDNA 1300002K09 gene 4.7 AV222559
2200002D01Rik RIKEN cDNA 2200002D01 gene 2.2 AK008617
2310014H01Rik RIKEN cDNA 2310014H01 gene 5.2 AK009340
2410006H16Rik RIKEN cDNA 2410006H16 gene 2.3 AA939619
2410129E14Rik RIKEN cDNA 2410129E14 gene 3.9 AA986082
2610510J17Rik RIKEN cDNA 2610510J17 gene 2.3 BM230253
2810052M02Rik RIKEN cDNA 2810052M02 gene 3.8 NM_023320
2810406C15Rik RIKEN cDNA 2810406C15 gene 4.8 BC025460
4833427B12Rik RIKEN cDNA 4833427B12 gene 3.1 AW488914
4930579G24Rik RIKEN cDNA 4930579G24 gene 2.8 BB821996
9030408N13Rik RIKEN cDNA 9030408N13 gene 10.9 NM_025779
9030623C06Rik RIKEN cDNA 9030623C06 gene 3.6 AF473907
9230117N10Rik RIKEN cDNA 9230117N10 gene 13.0 NM_133775
Abca1 ATP-binding cassette, sub-family A (ABC1), 2.3 BB144704
member 1
Abp1 amiloride binding protein 1 (amine oxidase, 6.3 BC021880
copper-containing)
Acta2 actin, alpha 2, smooth muscle, aorta 2.0 NM_007392
Actn1 actinin, alpha 1 3.9 BE853286
Adam12 a disintegrin and metallopeptidase domain 2.0 NM_007400
12 (meltrin alpha)
Adam8 a disintegrin and metallopeptidase domain 8 4.2 NM_007403
Adamts1 a disintegrin-like and metallopeptidse 6.0 D67076
(reprolysin type) with thrombospondin type
1 motif, 1
Adamts4 a disintegrin-like and metallopeptidase 2.2 BB443585
(reprolysin type) with thrombospondin type
1 motif, 4
Adfp adipose differentiation related protein 3.6 NM_007408
Adn adipsin 3.5 NM_013459
Aldh1a2 aldehyde dehydrogenase family 1, 11.2 NM_009022
subfamily A2
Alox5ap arachidonate 5-lipoxygenase activating 16.8 BC026209
protein
Anln anillin, actin binding protein (scraps 4.6 BI690018
homolog, Drosophila)
Anxa1 annexin A1 3.2 NM_010730
Anxa2 annexin A2 3.4 NM_007585
Anxa3 annexin A3 4.0 AW702161
Apobec1 apolipoprotein B editing complex 1 3.5 BC003792
Arg2 arginase type II 7.9 NM_009705
Arhgap11a Rho GTPase activating protein 11A 3.1 AV349116
Arpc1b actin related protein 2/3 complex, subunit 7.8 BE979985
1B
Asf1b ASF1 anti-silencing function 1 homolog B 4.4 BC003428
(S. cerevisiae)
Asns asparagine synthetase 6.1 AV212753
Atad2 ATPase family, AAA domain containing 2 6.0 BM206009
Aurka aurora kinase A 4.5 U80932
Aurkb aurora kinase B 4.6 BC003261
AW492955 expressed sequence AW492955 3.3 AW492955
Bak1 BCL2-antagonist/killer 1 3.4 NM_007523
Basp1 brain abundant, membrane attached signal 8.6 AK011545
protein 1
Bcl3 B-cell leukemia/lymphoma 3 3.8 NM_033601
Bgn biglycan 2.6 BC019502
Birc3 baculoviral IAP repeat-containing 3 6.6 NM_007464
Brrn1 barren homolog (Drosophila) 4.4 BB725358
Bub1 budding uninhibited by benzimidazoles 1 7.4 AF002823
homolog (S. cerevisiae)
C1qa complement component 1, q 12.6 NM_007572
subcomponent, alpha polypeptide
C1qb complement component 1, q 40.7 BB111335
subcomponent, beta polypeptide
C1qg complement component 1, q 15.2 NM_007574
subcomponent, gamma polypeptide
C3 complement component 3 40.6 K02782
C330027C09Rik RIKEN cDNA C330027C09 gene 4.3 AU018569
C3ar1 complement component 3a receptor 1 5.9 NM_009779
C79407 expressed sequence C79407 3.5 BE951628
Capg capping protein (actin filament), gelsolin-like 7.4 NM_007599
Ccl12 chemokine (C-C motif) ligand 12 14.5 U50712
Ccl2 chemokine (C-C motif) ligand 2 11.0 AF065933
Ccl6 chemokine (C-C motif) ligand 6 10.6 BC002073
Ccl9 chemokine (C-C motif) ligand 9 9.3 AF128196
Ccna2 cyclin A2 7.3 X75483
Ccnb1 cyclin B1 6.4 AU015121
Ccnb1-rs1 /// cyclin B1, related sequence 1 /// cyclin B1 5.3 NM_007629
Ccnb1
Ccnb2 cyclin B2 7.8 AK013312
Ccnf cyclin F 2.4 NM_007634
Ccr1 chemokine (C-C motif) receptor 1 9.8 AV231648
Ccr2 chemokine (C-C motif) receptor 2 21.3 BB148128
Ccr2 chemokine (C-C motif) receptor 2 18.1 BB148128
Cd14 CD14 antigen 20.8 NM_009841
Cd52 CD52 antigen 31.9 NM_013706
Cd68 CD68 antigen 11.9 BC021637
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 5.8 BB041150
Cdca1 cell division cycle associated 1 5.7 AK010351
Cdca3 cell division cycle associated 3 3.7 BI081061
Cdca5 cell division cycle associated 5 3.2 NM_026410
Cdca8 cell division cycle associated 8 3.7 AV307110
Cdh11 cadherin 11 3.8 NM_009866
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 3.9 AK007630
Cebpb CCAAT/enhancer binding protein (C/EBP), 3.8 NM_009883
beta
Cebpd CCAAT/enhancer binding protein (C/EBP), 8.0 BB831146
delta
Cenpf centromere autoantigen F 3.3 BE848253
Cfh complement component factor h 2.3 AI987976
Cfi complement component factor i 3.0 NM_007686
Chrnb1 cholinergic receptor, nicotinic, beta 2.3 M14537
polypeptide 1 (muscle)
Ckap2 cytoskeleton associated protein 2 2.9 BM208103
Ckap4 cytoskeleton-associated protein 4 2.1 BB818012
Cklfsf3 chemokine-like factor super family 3 3.4 NM_024217
Clca1 /// Clca2 chloride channel calcium activated 1 /// 3.7 AF108501
chloride channel calcium activated 2
Clec4a2 C-type lectin domain family 4, member a2 3.0 NM_011999
Clec4a2 /// C-type lectin domain family 4, member a2 /// 2.7 BC006623
Clec4b C-type lectin domain family 4, member b
Clec4a3 C-type lectin domain family 4, member a3 23.8 AK014135
Clec4n C-type lectin domain family 4, member n 6.6 NM_020001
Clec7a C-type lectin domain family 7, member a 13.0 NM_020008
Clu clusterin 3.6 AV152288
Cnn2 calponin 2 3.9 BI663014
Col15a1 procollagen, type XV 2.1 AF011450
Col1a1 procollagen, type I, alpha 1 8.5 BI794771
Col1a2 procollagen, type I, alpha 2 9.6 BF227507
Col1a2 procollagen, type I, alpha 2 5.4 BF227507
Col3a1 procollagen, type III, alpha 1 13.4 AW550625
Col5a1 procollagen, type V, alpha 1 3.6 AW744319
Col5a2 procollagen, type V, alpha 2 7.2 AV229424
Col6a1 procollagen, type VI, alpha 1 2.1 NM_009933
Col6a2 procollagen, type VI, alpha 2 2.4 BI455189
Col6a3 procollagen, type VI, alpha 3 2.7 AF064749
Col8a1 procollagen, type VIII, alpha 1 3.1 AV292255
Colec12 collectin sub-family member 12 2.4 NM_130449
Cp ceruloplasmin 6.8 BB332449
Cp ceruloplasmin 6.0 BB009037
Crlf1 cytokine receptor-like factor 1 3.9 NM_018827
Cry1 cryptochrome 1 (photolyase-like) 2.3 BG069864
Csrp1 cysteine and glycine-rich protein 1 2.4 BF124540
Cstb cystatin B 3.8 NM_007793
Ctsc cathepsin C 10.5 NM_009982
Ctss cathepsin S 19.4 NM_021281
Cx3cl1 chemokine (C—X3—C motif) ligand 1 2.3 AF010586
Cxcl1 chemokine (C—X—C motif) ligand 1 10.9 NM_008176
Cxcl14 chemokine (C—X—C motif) ligand 14 10.6 AF252873
Cybb cytochrome b-245, beta polypeptide 21.0 AV373944
D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5 9.6 NM_033075
Dcamkl1 Double cortin and calcium/calmodulin- 9.2 BB757120
dependent protein kinase-like 1, mRNA
(cDNA clone IMAGE: 5006471)
Dck deoxycytidine kinase 11.8 BB030204
Dpt dermatopontin 3.2 NM_019759
Dpysl3 dihydropyrimidinase-like 3 2.5 AV162270
Ect2 ect2 oncogene 3.3 NM_007900
Efemp2 epidermal growth factor-containing fibulin- 2.0 NM_021474
like extracellular matrix protein 2
Efhd2 EF hand domain containing 2 5.6 AK007560
Emilin1 elastin microfibril interfacer 1 2.1 NM_133918
Emr1 EGF-like module containing, mucin-like, 4.9 U66888
hormone receptor-like sequence 1
Entpd1 ectonucleoside triphosphate 4.0 BI151440
diphosphohydrolase 1
Ercc6l excision repair cross-complementing rodent 2.9 BC004701
repair deficiency complementation group 6-
like
Esco2 establishment of cohesion 1 homolog 2 (S. cerevisiae) 3.7 AK010391
F13a1 coagulation factor XIII, A1 subunit 6.2 NM_028784
F2r coagulation factor II (thrombin) receptor 3.3 AV024285
Fbn1 fibrillin 1 4.0 NM_007993
Fcer1g Fc receptor, IgE, high affinity I, gamma 16.5 NM_010185
polypeptide
Fcgr3 Fc receptor, IgG, low affinity III 14.4 NM_010188
Fga fibrinogen, alpha polypeptide 8.6 BC005467
Fgg fibrinogen, gamma polypeptide 3.1 NM_133862
Fignl1 fidgetin-like 1 6.4 NM_021891
Flna filamin, alpha 2.9 BM233746
Fn1 fibronectin 1 2.8 BC004724
Fshprh1 FSH primary response 1 2.1 BB258991
Fstl1 follistatin-like 1 4.5 BI452727
Fxyd5 FXYD domain-containing ion transport 8.7 NM_008761
regulator 5
Gch1 GTP cyclohydrolase 1 2.4 NM_008102
Gda guanine deaminase 16.3 AW911807
Golph2 golgi phosphoprotein 2 2.4 BC011152
H2afx H2A histone family, member X 2.0 NM_010436
Havcr1 hepatitis A virus cellular receptor 1 7.8 NM_134248
Hells helicase, lymphoid specific 10.2 NM_008234
Hesx1 homeo box gene expressed in ES cells 2.7 NM_010420
Hmga1 high mobility group AT-hook 1 2.8 NM_016660
Hmmr hyaluronan mediated motility receptor 3.3 X64550
(RHAMM)
Hp haptoglobin 5.9 NM_017370
Icam1 intercellular adhesion molecule 10.5 BC008626
Ifitm1 interferon induced transmembrane protein 1 5.2 BC027285
Ifitm3 interferon induced transmembrane protein 3 5.0 BC010291
Il1b interleukin 1 beta 3.3 BC011437
Il6 interleukin 6 10.3 NM_031168
Inhbb inhibin beta-B 4.7 BB253137
Isgf3g interferon dependent positive acting 3.6 NM_008394
transcription factor 3 gamma
Itgam integrin alpha M 6.5 NM_008401
Kdelr3 KDEL (Lys-Asp-Glu-Leu) endoplasmic 2.4 NM_134090
reticulum protein retention receptor 3
Kif11 kinesin family member 11 4.7 BM234447
Kif20a kinesin family member 20A 2.4 NM_009004
Kif22 kinesin family member 22 8.2 BB251322
Kif2c kinesin family member 2C 4.0 BB104669
Klf4 Kruppel-like factor 4 (gut) 2.7 BG069413
Lbp lipopolysaccharide binding protein 4.6 NM_008489
Lcn2 lipocalin 2 57.7 X14607
Lcp1 lymphocyte cytosolic protein 1 16.8 NM_008879
Lepr leptin receptor 2.4 BM124366
Lgals1 lectin, galactose binding, soluble 1 3.5 AI642438
Lgals3 lectin, galactose binding, soluble 3 3.9 X16834
Lhfp lipoma HMGIC fusion partner 2.0 AV149705
Lig1 ligase I, DNA, ATP-dependent 3.4 NM_010715
Lilrb3 leukocyte immunoglobulin-like receptor, 7.3 U96693
subfamily B (with TM and ITIM domains),
member 3
Litaf LPS-induced TN factor 4.5 AV360881
Lmna lamin A 2.4 AV238225
Lox lysyl oxidase 7.5 M65143
Lrg1 leucine-rich alpha-2-glycoprotein 1 4.5 NM_029796
Lum lumican 2.8 AK014312
Ly86 lymphocyte antigen 86 21.0 NM_010745
Lyzs lysozyme 26.8 AW208566
Lzp-s P lysozyme structural 22.0 AV066625
Mad2l1 MAD2 (mitotic arrest deficient, homolog)- 3.6 NM_019499
like 1 (yeast)
Marcks myristoylated alanine rich protein kinase C 2.8 AW546141
substrate
Marcksl1 MARCKS-like 1 4.7 AV110584
Mcm2 minichromosome maintenance deficient 2 3.5 NM_008564
mitotin (S. cerevisiae)
Mcm3 minichromosome maintenance deficient 3 4.9 C80350
(S. cerevisiae)
Mcm4 minichromosome maintenance deficient 4 5.1 BC013094
homolog (S. cerevisiae)
Mcm7 minichromosome maintenance deficient 7 2.7 BB464359
(S. cerevisiae)
Melk maternal embryonic leucine zipper kinase 4.4 NM_010790
Mfap5 microfibrillar associated protein 5 8.0 NM_015776
Mgp matrix Gla protein 3.0 NM_008597
Mgst1 microsomal glutathione S-transferase 1 2.1 BI150149
Mmd monocyte to macrophage differentiation- 2.0 BC021914
associated
Mmp14 matrix metallopeptidase 14 (membrane- 4.5 NM_008608
inserted)
Mmp7 matrix metallopeptidase 7 4.1 NM_010810
Ms4a7 membrane-spanning 4-domains, subfamily 5.5 BC024402
A, member 7
Mt2 metallothionein 2 5.3 AA796766
Mvp major vault protein 3.5 NM_080638
Myadm myeloid-associated differentiation marker 2.5 BB500055
Myc myelocytomatosis oncogene 3.5 BC006728
Myh9 myosin, heavy polypeptide 9, non-muscle 2.4 C80049
Ncf1 neutrophil cytosolic factor 1 6.8 BE370703
Nek2 NIMA (never in mitosis gene a)-related 2.2 C77054
expressed kinase 2
Nek6 NIMA (never in mitosis gene a)-related 2.6 BB528391
expressed kinase 6
Nfkbia nuclear factor of kappa light chain gene 4.8 AI462015
enhancer in B-cells inhibitor, alpha
Nfkbiz nuclear factor of kappa light polypeptide 18.1 AB026551
gene enhancer in B-cells inhibitor, zeta
Nrm nurim (nuclear envelope membrane protein) 2.0 NM_134122
Nuak2 NUAK family, SNF1-like kinase, 2 2.1 AK004737
Nusap1 nucleolar and spindle associated protein 1 7.4 BC009096
Olfml3 olfactomedin-like 3 2.0 NM_133859
Osmr oncostatin M receptor 7.9 AB015978
P2ry6 pyrimidinergic receptor P2Y, G-protein 5.9 BC027331
coupled, 6
Pbk PDZ binding kinase 3.5 NM_023209
Pdgfrb platelet derived growth factor receptor, beta 2.0 AA499047
polypeptide
Pdlim7 PDZ and LIM domain 7 2.8 AK010339
Pdxk pyridoxal (pyridoxine, vitamin B6) kinase 2.0 BG063905
Pea15 phosphoprotein enriched in astrocytes 15 2.3 AI323543
Pfc properdin factor, complement 5.0 BB800282
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 5.3 BI684288
Pld4 phospholipase D family, member 4 13.0 BB210623
Plk4 polo-like kinase 4 (Drosophila) 6.0 AI385771
Plp2 proteolipid protein 2 2.5 AK012816
Pltp phospholipid transfer protein 2.7 NM_011125
Pola1 polymerase (DNA directed), alpha 1 2.9 NM_008892
Pole polymerase (DNA directed), epsilon 3.3 NM_011132
Prc1 protein regulator of cytokinesis 1 2.6 BC005475
Ptger4 prostaglandin E receptor 4 (subtype EP4) 6.3 BC011193
Ptgfrn prostaglandin F2 receptor negative 2.2 AV253087
regulator
Ptgs2 prostaglandin-endoperoxide synthase 2 5.3 M94967
Ptprc protein tyrosine phosphatase, receptor type, C 27.0 NM_011210
Pycard PYD and CARD domain containing 7.6 BG084230
Racgap1 Rac GTPase-activating protein 1 4.7 NM_012025
Rad51 RAD51 homolog (S. cerevisiae) 8.4 NM_011234
Rcn1 reticulocalbin 1 5.4 NM_009037
Relb avian reticuloendotheliosis viral (v-rel) 3.7 NM_009046
oncogene related B
Rhob ras homolog gene family, member B 3.8 BC018275
Ris2 retroviral integration site 2 2.4 AF477481
Rprc1 arginine/proline rich coiled-coil 1 2.2 BC019977
Rras Harvey rat sarcoma oncogene, subgroup R 2.6 NM_009101
Rrm2 ribonucleotide reductase M2 9.1 NM_009104
S100a10 S100 calcium binding protein A10 2.4 AV295650
(calpactin)
S100a11 S100 calcium binding protein A11 2.6 BC021916
(calizzarin)
S100a6 S100 calcium binding protein A6 (calcyclin) 4.6 NM_011313
S100a8 S100 calcium binding protein A8 7.6 NM_013650
(calgranulin A)
S100a9 S100 calcium binding protein A9 7.1 NM_009114
(calgranulin B)
Saa1 serum amyloid A 1 9.6 NM_009117
Sart2 squamous cell carcinoma antigen 6.8 BM207218
recognized by T cells 2
Scarb2 scavenger receptor class B, member 2 2.2 NM_007644
Sdc1 syndecan 1 3.3 BB533095
Serpina3n serine (or cysteine) peptidase inhibitor, 5.6 NM_009252
clade A, member 3N
Serpinb6b serine (or cysteine) peptidase inhibitor, 5.6 NM_011454
clade B, member 6b
Serpine1 serine (or cysteine) peptidase inhibitor, 5.4 NM_008871
clade E, member 1
Sertad4 SERTA domain containing 4 7.2 BQ174721
Sh3bgrl3 SH3 domain binding glutamic acid-rich 5.8 NM_080559
protein-like 3
Shcbp1 Shc SH2-domain binding protein 1 5.4 NM_011369
Sirpb1 signal-regulatory protein beta 1 26.9 AI662854
Slamf9 SLAM family member 9 4.0 NM_029612
Slc15a3 solute carrier family 15, member 3 13.3 NM_023044
Slc25a24 solute carrier family 25 (mitochondrial 5.9 BM230959
carrier, phosphate carrier), member 24
Slc34a2 solute carrier family 34 (sodium phosphate), 6.7 NM_011402
member 2
Slc7a12 solute carrier family 7 (cationic amino acid 3.6 NM_080852
transporter, y+ system), member 12
Smc2l1 SMC2 structural maintenance of 6.1 NM_008017
chromosomes 2-like 1 (yeast)
Smpdl3b sphingomyelin phosphodiesterase, acid-like 7.6 NM_133888
3B
Socs3 suppressor of cytokine signaling 3 29.6 BB831725
Sp100 nuclear antigen Sp100 2.6 AV284523
Sparc secreted acidic cysteine rich glycoprotein 2.1 NM_009242
Spbc24 spindle pole body component 24 homolog 2.3 BF577722
(S. cerevisiae)
Stat3 signal transducer and activator of 3.1 AK004083
transcription 3
Tacc3 transforming, acidic coiled-coil containing 4.0 NM_011524
protein 3
Tagln2 transgelin 2 2.2 C76322
Tcf19 transcription factor 19 2.5 BC004617
Tgfb1 transforming growth factor, beta 1 3.2 NM_011577
Tgfbi transforming growth factor, beta induced 31.0 BB533460
Tgm2 transglutaminase 2, C polypeptide 2.2 BC016492
Timp1 tissue inhibitor of metalloproteinase 1 40.8 BC008107
Tlr2 toll-like receptor 2 9.8 NM_011905
Tmcc2 transmembrane and coiled-coil domains 2 2.1 AK004359
Tmepai transmembrane, prostate androgen induced 2.4 AV370981
RNA
Tmsb10 thymosin, beta 10 12.3 NM_025284
Tnfrsf12a tumor necrosis factor receptor superfamily, 2.7 NM_013749
member 12a
Tpm2 tropomyosin 2, beta 2.3 BC024358
Tpm4 tropomyosin 4 3.5 AV122663
Tpx2 TPX2, microtubule-associated protein 3.9 AK011311
homolog (Xenopus laevis)
Tpx2 TPX2, microtubule-associated protein 2.0 AK011311
homolog (Xenopus laevis)
Trip13 thyroid hormone receptor interactor 13 8.2 AK010336
Tuba1 tubulin, alpha 1 3.8 NM_011653
Tubb2 /// tubulin, beta 2 /// RIKEN cDNA 2410129E14 3.9 BC003475
2410129E14Rik gene /// similar to TUBULIN BETA CHAIN
/// LOC544939 (T BETA-15)
Tubb5 tubulin, beta 5 3.7 NM_011655
Tubb6 tubulin, beta 6 4.0 NM_026473
Tyrobp TYRO protein tyrosine kinase binding 17.4 NM_011662
protein
Uhrf1 ubiquitin-like, containing PHD and RING 9.5 BB702754
finger domains, 1
Vasp vasodilator-stimulated phosphoprotein 3.1 BC015289
Vim vimentin 17.3 AV147875
Wisp1 WNT1 inducible signaling pathway protein 1 2.9 NM_018865
Zwilch Zwilch, kinetochore associated, homolog 3.2 BC027435
(Drosophila)
Zyx zyxin 2.2 NM_011777
Other Embodiments It is to be understood that while the invention has been described in conjunction with the detailed description thereof, the foregoing description is intended to illustrate and not limit the scope of the invention, which is defined by the scope of the appended claims. Other aspects, advantages, and modifications are within the scope of the following claims.
