MEDICAL DEVICES WITH A FLEXIBLE ELECTRODE ASSEMBLY COUPLED TO AN ABLATION TIP
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter for use in cardiac mapping and/or ablation. The catheter may include an elongate catheter shaft having a distal ablation electrode region capable of ablating tissue. An electrode assembly may be coupled to the distal ablation electrode region. The electrode assembly may include a flexible circuit having one or more electrodes disposed thereon.
This application is a continuation application of U.S. application Ser. No. 14/922,023, filed Oct. 23, 2015, which claims priority to Provisional Application No. 62/068,334, filed Oct. 24, 2014, which is herein incorporated by reference in its entirety.
TECHNICAL FIELDThe present disclosure pertains to medical devices, and methods for manufacturing medical devices. More particularly, the present disclosure pertains to for cardiac mapping and/or ablation.
BACKGROUNDA wide variety of intracorporeal medical devices have been developed for medical use, for example, intravascular use. Some of these devices include guidewires, catheters, and the like. These devices are manufactured by any one of a variety of different manufacturing methods and may be used according to any one of a variety of methods. Of the known medical devices and methods, each has certain advantages and disadvantages. There is an ongoing need to provide alternative medical devices as well as alternative methods for manufacturing and using medical devices.
SUMMARYThis disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example catheter may include a catheter for use in cardiac mapping and/or ablation. The catheter comprises:
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- an elongate catheter shaft having a distal ablation electrode region;
- an electrode assembly coupled to the distal ablation electrode region; and
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon.
Alternatively or additionally to any of the embodiments above, the distal ablation electrode region has an opening formed therein and wherein the electrode assembly extends through the opening.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a region that is disposed along a distal end of the distal ablation electrode region.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a plurality of arm regions and wherein each of the arm regions includes at least one electrode.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes three or more arm regions.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes four or more arm regions.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a mechanical locking end region that is capable of mechanically securing the electrode assembly to the distal ablation electrode region.
Alternatively or additionally to any of the embodiments above, the distal ablation electrode region has an opening formed therein and wherein the mechanical locking end region extends through the opening.
Alternatively or additionally to any of the embodiments above, the catheter shaft includes an inner channel, wherein the distal ablation electrode region includes a first opening and a second opening, and wherein the electrode assembly extends along the inner channel, through the first opening, along an outer surface of the distal ablation electrode region, and through the second opening.
Alternatively or additionally to any of the embodiments above, the electrode assembly is adhesively bonded to the distal ablation electrode region.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes one or more electrode regions and one or more electrically insulated regions.
Alternatively or additionally to any of the embodiments above, the electrode assembly extends circumferentially around the distal ablation electrode region.
Alternatively or additionally to any of the embodiments above, the electrode assembly is designed to bow radially outward from the distal ablation electrode region.
Alternatively or additionally to any of the embodiments above, the distal ablation electrode region includes a platinum ablation tip electrode.
Methods for manufacturing a medical device are also disclosed. The methods may comprise:
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- inserting an electrode assembly into a channel formed within a distal ablation tip of a catheter;
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon;
- wherein the distal ablation tip includes a first opening and a second opening; and
- extending the electrode assembly extends through the first opening, along an outer surface of the distal ablation tip, and through the second opening.
Another embodiment of a catheter for use in cardiac mapping and/or ablation may comprise:
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- an elongate catheter shaft having an inner channel and a distal end region;
- a distal ablation tip capable of ablating tissue disposed at the distal end region;
- an electrode assembly coupled to the distal ablation tip;
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon;
- wherein the distal ablation electrode region includes a first opening and a second opening;
- wherein the electrode assembly extends along the inner channel, through the first opening, along an outer surface of the distal ablation tip, and through the second opening.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a region that is disposed along a distal end of the distal ablation tip.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a plurality of arm regions and wherein each of the arm regions includes at least one electrode.
Alternatively or additionally to any of the embodiments above, the electrode assembly includes a mechanical locking end region that is capable of mechanically securing the electrode assembly to the distal ablation tip.
Alternatively or additionally to any of the embodiments above, the mechanical locking end region extends through the first opening, the second opening, or both.
The above summary of some embodiments is not intended to describe each disclosed embodiment or every implementation of the present disclosure. The Figures, and Detailed Description, which follow, more particularly exemplify these embodiments.
While multiple embodiments are disclosed, still other embodiments of the present invention will become apparent to those skilled in the art from the following detailed description, which shows and describes illustrative embodiments of the invention. Accordingly, the drawings and detailed description are to be regarded as illustrative in nature and not restrictive.
The disclosure may be more completely understood in consideration of the following detailed description in connection with the accompanying drawings, in which:
While the disclosure is amenable to various modifications and alternative forms, specifics thereof have been shown by way of example in the drawings and will be described in detail. It should be understood, however, that the intention is not to limit the invention to the particular embodiments described. On the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the disclosure.
DETAILED DESCRIPTIONFor the following defined terms, these definitions shall be applied, unless a different definition is given in the claims or elsewhere in this specification.
All numeric values are herein assumed to be modified by the term “about”, whether or not explicitly indicated. The term “about” generally refers to a range of numbers that one of skill in the art would consider equivalent to the recited value (e.g., having the same function or result). In many instances, the terms “about” may include numbers that are rounded to the nearest significant figure.
The recitation of numerical ranges by endpoints includes all numbers within that range (e.g. 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, and 5).
As used in this specification and the appended claims, the singular forms “a”, “an”, and “the” include plural referents unless the content clearly dictates otherwise. As used in this specification and the appended claims, the term “or” is generally employed in its sense including “and/or” unless the content clearly dictates otherwise.
It is noted that references in the specification to “an embodiment”, “some embodiments”, “other embodiments”, etc., indicate that the embodiment described may include one or more particular features, structures, and/or characteristics. However, such recitations do not necessarily mean that all embodiments include the particular features, structures, and/or characteristics. Additionally, when particular features, structures, and/or characteristics are described in connection with one embodiment, it should be understood that such features, structures, and/or characteristics may also be used connection with other embodiments whether or not explicitly described unless clearly stated to the contrary.
The following detailed description should be read with reference to the drawings in which similar elements in different drawings are numbered the same. The drawings, which are not necessarily to scale, depict illustrative embodiments and are not intended to limit the scope of the invention.
Alternatively, or in addition, a device, other than shaft 12, that may be utilized to apply ablation energy to and/or map a target area, may be operatively coupled to at least one or more of RF generator 14 and processor 16. RF generator 14 may be capable of delivering and/or may be configured to deliver ablation energy to shaft 12 in a controlled manner in order to ablate target area sites identified by processor 16. Although the processor 16 and RF generator 14 may be shown as discrete components, these components or features of components may be incorporated into a single device. System 10 may include any of one or more other features, as desired.
In at least some embodiments, shaft 12 may include a handle 18, which may have an actuator 20 (e.g., a control knob or other actuator). The handle 18 (e.g., a proximal handle) may be positioned at a proximal end of shaft 12, for example. Illustratively, shaft 12 may include a flexible body having a having a distal portion which may include the one or more electrodes. For example, the distal portion of shaft 12 may include one or more of a plurality of ring electrodes 22, a distal ablation tip electrode 24, and a plurality of micro-electrodes or micro-electrode assemblies 26 disposed or otherwise positioned within and/or electrically isolated from distal ablation tip electrode 24.
Shaft 12 may be steerable to facilitate navigating the vasculature of a patient or navigating other lumens. Illustratively, a distal portion 13 of shaft 12 may be deflected by manipulation of actuator 20 to effect steering shaft 12. In some instances, distal portion 13 of shaft 12 may be deflected to position distal ablation tip electrode 24 and/or micro-electrode assemblies 26 adjacent target tissue or to position the distal portion 13 of shaft 12 for another suitable purpose. Additionally, or alternatively, distal portion 13 of shaft 12 may have a pre-formed shape adapted to facilitate positioning distal ablation tip electrode 24 and/or micro-electrode assemblies 26 adjacent a target tissue. Illustratively, the preformed shape of distal portion 13 of shaft 12 may be a radiused shape (e.g., a generally circular shape or a generally semi-circular shape) and/or may be oriented in a plane transverse to a general longitudinal direction of shaft 12. These are just examples.
In some instances, system 10 may be utilized in ablation procedures on a patient. Illustratively, shaft 12 may be configured to be introduced into or through vasculature of a patient and/or into or through any other lumen or cavity. In one example, shaft 12 may be inserted through the vasculature of the patient and into one or more chambers of the patient's heart (e.g., a target area). When in the patient's vasculature or heart, shaft 12 may be used to map and/or ablate myocardial tissue using the ring electrodes 22, micro-electrode assemblies 26, and/or distal ablation tip electrode 24. In some instances, distal ablation tip electrode 24 may be configured to apply ablation energy to myocardial tissue of the heart of a patient.
In some instances, micro-electrode assemblies 26 may be circumferentially distributed about a distal ablation tip electrode 24. In some instances, system 10 may not include distal ablation tip electrode 24 and, in such embodiments, micro-electrode assemblies 26 may be circumferentially distributed about shaft 12 (e.g., along a distal tip of shaft 12). In general, micro-electrode assemblies 26, as their name suggests, are relatively small in size (e.g., smaller than distal ablation tip electrode 24). Micro-electrode assemblies 26 may be capable of operating, or configured to operate, in unipolar or bipolar sensing modes. In some cases, micro-electrode assemblies 26 may define and/or at least partially form one or more bipolar microelectrode pairs. In an illustrative instance, shaft 12 may have three micro-electrode assemblies 26 distributed about the circumference of distal ablation tip electrode 24, such that the circumferentially spaced microelectrodes may form respective bipolar microelectrode pairs. Each bipolar microelectrode pair may be capable of generating, or may be configured to generate, an output signal corresponding to a sensed electrical activity (e.g., an electrogram (EGM) reading) of the myocardial tissue proximate thereto. Additionally or alternatively to the circumferentially spaced micro-electrode assemblies 26, shaft 12 may include one or more forward facing micro-electrode assemblies 26 (not shown). The forward facing micro-electrode assemblies 26 may be generally centrally located within distal ablation tip electrode 24 and/or at an end of a tip of shaft 12.
In some examples, micro-electrode assemblies 26 may be operatively coupled to processor 16 and the generated output signals from micro-electrode assemblies 26 may be sent to the processor 16 of ablation system 10 for processing in one or more manners discussed herein and/or for processing in other manners. Illustratively, an EGM reading or signal of an output signal from a bipolar microelectrode pair may at least partially form the basis of a contact assessment, ablation area assessment (e.g., tissue viability assessment), and/or an ablation progress assessment (e.g., a lesion formation/maturation analysis), as discussed below.
Distal ablation tip electrode 24 may be a suitable length and may have a suitable number of micro-electrode assemblies 26 positioned therein and spaced circumferentially and/or longitudinally about distal ablation tip electrode 24. In some instances, distal ablation tip electrode 24 may have a length of between one (1) mm and twenty (20) mm, three (3) mm and seventeen (17) mm, or six (6) mm and fourteen (14) mm. In one illustrative example, distal ablation tip electrode 24 may have an axial length of about eight (8) mm. Distal ablation tip electrode 24 may be formed from other otherwise include platinum and/or other suitable materials. These are just examples.
Processor 16 may be capable of processing or may be configured to process the electrical signals of the output signals from micro-electrode assemblies 26 and/or ring electrodes 22. Based, at least in part, on the processed output signals from micro-electrode assemblies 26 and/or ring electrodes 22, processor 16 may generate an output to a display (not shown) for use by a physician or other user. In instances where an output is generated to a display and/or other instances, processor 16 may be operatively coupled to or otherwise in communication with the display. Illustratively, the display may include various static and/or dynamic information related to the use of system 10. In one example, the display may include one or more of an image of the target area, an image of shaft 12, and information related to EGMs, which may be analyzed by the user and/or by a processor of system 10 to determine the existence and/or location of arrhythmia substrates within the heart, to determine the location of shaft 12 within the heart, and/or to make other determinations relating to use of shaft 12 and/or other elongated members.
System 10 may include an indicator in communication with processor 16. The indicator may be capable of providing an indication related to a feature of the output signals received from one or more of the electrodes of shaft 12. In one example of an indicator, an indication to the clinician about a characteristic of shaft 12 and/or the myocardial tissue interacted with and/or being mapped may be provided on the display. In some cases, the indicator may provide a visual and/or audible indication to provide information concerning the characteristic of shaft 12 and/or the myocardial tissue interacted with and/or being mapped.
In some instances, one or more micro-electrode assemblies (e.g., similar to micro-electrode assemblies 26) may be disposed along distal ablation tip electrode 124. In some of these and in other embodiments, an electrode assembly 130 may be coupled to distal ablation tip electrode 124. Electrode assembly 130 may include one or more electrodes or electrode regions 132. Electrodes 132 may include monopolar electrodes, one or more pairs of bipoloar electrodes, or combinations thereof. Electrodes 132 may also take the form of sensors such as impedance and/or contact sensors. A proximal connector 134 may be disposed along (e.g., within) catheter shaft 112. Proximal connector 134 may be used to connect electrode assembly 130 with a suitable processor/generator.
The use of electrode assembly 130 may be desirable for a number of reasons. For example, electrode assembly 130 may allow for electrodes 132 to be disposed at the front face or distal end of distal ablation tip 124. This may allow electrodes 132 to be used to sense contact between distal ablation tip 124 and a target tissue. In addition, because it may have a relatively small, compact shape, the use of electrode assembly 130 may free up additional space along and/or within distal ablation tip 124 for other useful structures such as micro-electrodes, force sensors, contact sensors, magnetic sensors, or the like. Moreover, electrode assembly 130 may be wrapped or otherwise disposed along distal ablation tip 124 in a manner that reduces protruding edges that could catch on tissue, other medical devices, etc. Furthermore, by weaving electrode assembly 130 through openings in distal ablation tip 124, RF edge effects may be reduced or minimized.
Electrode assembly 130 may take the form of a flexible circuit. For example, electrode assembly 130 may include a substrate with one or more electrodes (e.g., electrodes 132) disposed thereon. The substrate may include a polymeric material (e.g., such as polyimide or other suitable materials including those disclosed herein). Electrode assembly 130 may include a coating such as a parylene coating or other suitable biocompatible coating. Electrodes 132 may be sputtered onto the substrate with iridium oxide. In some of these and in other embodiments, electrodes 132 may be copper or gold electrodes (or electrodes formed of other suitable materials) disposed along the substrate. In some instances, a temperature or other sensor may be disposed along the substrate. In addition, a magnetic sensing coil, piezoelectric film, MEMS force sensor, or the like may be coupled to assembly 130. Some example flexible circuits that may suitable for use as electrode assembly 130 may include or resemble those disclosed in U.S. Patent Application Pub. No. US 2013/0165926, the entire disclosure of which is herein incorporated by reference. The use of a flex circuit may be desirable by allowing for batch processing at relatively high volumes so that manufacturability of system 110 may be increased.
In some instances, electrode assembly 130 may include an inner insulating layer contacts distal ablation tip 124 and electrically insulates electrode assembly 130 from distal ablation tip 124. Electrodes 132 may be disposed on the insulating layer. Alternatively, electrodes 132 may take the form of a conductive layer or trace disposed along the insulating layer. The conductive layer may extend along essentially the entire length of the insulating layer or along one or more discrete sections thereof. Numerous configurations are contemplated.
Proximal connector 134 may be coupled to a suitable processor/generator using flying leads, ribbonized cable, or by simply extending proximal connector 134 to the processor/generator. When connecting proximal connector 134 to another suitable device or wire, terminals may be disposed along proximal connector 134. The terminals may be formed by wire bonding, hot bar soldering, anisotropic conductive films, soldering, or the like.
The use of electrode assembly 630 may desirable for a number of reasons. For example, using electrode assembly 630 may allow for assembly of system 610 while reducing/minimizing the possibility of damaging iridium oxide sputtered electrodes and/or to the parylene coating (e.g., when electrode assembly 630 includes such structures). The length of electrode assembly 630 exposed along the outer surface of system 610 may also be reduced, which may reduce the likelihood of electrode assembly 630 catching during a procedure and also may reduce the amount of surface area along distal ablation tip 624 that may be covered.
While
While
Electrode assembly 1530 may be disposed along distal ablation tip 1524. In this example, electrode assembly 1530 may extend to and/or along the distal end of distal ablation tip 1524 as can be seen in
Electrode assembly 1630 may be disposed along distal ablation tip 1624. Electrode assembly 1630 may include insulating layer 1650 and electrode region 1632.
Electrode assembly 1830 may be disposed along distal ablation tip 1824. Electrode assembly 1830 may include a plurality of insulating layers 1850 and electrode region 1832 disposed between insulating layers 1850.
Electrode assembly 1930 may be disposed along distal ablation tip 1924. Electrode assembly 1930 may include a plurality of insulating layers 1950 and a plurality of electrode regions 1932a/1932b disposed between insulating layers 1950.
The materials that can be used for the various components of system 10 and/or other systems disclosed herein (e.g., shafts, micro-electrodes, distal ablation tip electrodes, flexible circuits, substrates, etc.) may include metals, metal alloys, polymers, metal-polymer composites, ceramics, combinations thereof, and the like, or other suitable material. Some examples of suitable polymers may include polytetrafluoroethylene (PTFE), ethylene tetrafluoroethylene (ETFE), fluorinated ethylene propylene (FEP), polyoxymethylene (POM, for example, DELRIN® available from DuPont), polyether block ester, polyurethane (for example, Polyurethane 85A), polypropylene (PP), polyvinylchloride (PVC), polyether-ester (for example, ARNITEL® available from DSM Engineering Plastics), ether or ester based copolymers (for example, butylene/poly(alkylene ether) phthalate and/or other polyester elastomers such as HYTREL® available from DuPont), polyamide (for example, DURETHAN® available from Bayer or CRISTAMID® available from Elf Atochem), elastomeric polyamides, block polyamide/ethers, polyether block amide (PEBA, for example available under the trade name PEBAX®), ethylene vinyl acetate copolymers (EVA), silicones, polyethylene (PE), Marlex high-density polyethylene, Marlex low-density polyethylene, linear low density polyethylene (for example REXELL®), polyester, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), polytrimethylene terephthalate, polyethylene naphthalate (PEN), polyetheretherketone (PEEK), polyimide (PI), polyetherimide (PEI), polyphenylene sulfide (PPS), polyphenylene oxide (PPO), poly paraphenylene terephthalamide (for example, KEVLAR®), polysulfone, nylon, nylon-12 (such as GRILAMID@ available from EMS American Grilon), perfluoro(propyl vinyl ether) (PFA), ethylene vinyl alcohol, polyolefin, polystyrene, epoxy, polyvinylidene chloride (PVdC), poly(styrene-b-isobutylene-b-styrene) (for example, SIBS and/or SIBS 50A), polycarbonates, ionomers, biocompatible polymers, other suitable materials, or mixtures, combinations, copolymers thereof, polymer/metal composites, and the like.
Some examples of suitable metals and metal alloys include stainless steel, such as 304V, 304L, and 316LV stainless steel; mild steel; nickel-titanium alloy such as linear-elastic and/or super-elastic nitinol; other nickel alloys such as nickel-chromium-molybdenum alloys (e.g., UNS: N06625 such as INCONEL® 625, UNS: N06022 such as HASTELLOY® C-22®, UNS: N10276 such as HASTELLOY® C276®, other HASTELLOY® alloys, and the like), nickel-copper alloys (e.g., UNS: N04400 such as MONEL® 400, NICKELVAC® 400, NICORROS® 400, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nickel-molybdenum alloys (e.g., UNS: N10665 such as HASTELLOY® ALLOY B2®), other nickel-chromium alloys, other nickel-molybdenum alloys, other nickel-cobalt alloys, other nickel-iron alloys, other nickel-copper alloys, other nickel-tungsten or tungsten alloys, and the like; cobalt-chromium alloys; cobalt-chromium-molybdenum alloys (e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like); platinum enriched stainless steel; titanium; combinations thereof; and the like; or any other suitable material.
As alluded to herein, within the family of commercially available nickel-titanium or nitinol alloys, is a category designated “linear elastic” or “non-super-elastic” which, although may be similar in chemistry to conventional shape memory and super elastic varieties, may exhibit distinct and useful mechanical properties. Linear elastic and/or non-super-elastic nitinol may be distinguished from super elastic nitinol in that the linear elastic and/or non-super-elastic nitinol does not display a substantial “superelastic plateau” or “flag region” in its stress/strain curve like super elastic nitinol does. Instead, in the linear elastic and/or non-super-elastic nitinol, as recoverable strain increases, the stress continues to increase in a substantially linear, or a somewhat, but not necessarily entirely linear relationship until plastic deformation begins or at least in a relationship that is more linear that the super elastic plateau and/or flag region that may be seen with super elastic nitinol. Thus, for the purposes of this disclosure linear elastic and/or non-super-elastic nitinol may also be termed “substantially” linear elastic and/or non-super-elastic nitinol.
In some cases, linear elastic and/or non-super-elastic nitinol may also be distinguishable from super elastic nitinol in that linear elastic and/or non-super-elastic nitinol may accept up to about 2-5% strain while remaining substantially elastic (e.g., before plastically deforming) whereas super elastic nitinol may accept up to about 8% strain before plastically deforming. Both of these materials can be distinguished from other linear elastic materials such as stainless steel (that can also can be distinguished based on its composition), which may accept only about 0.2 to 0.44 percent strain before plastically deforming.
In some embodiments, the linear elastic and/or non-super-elastic nickel-titanium alloy is an alloy that does not show any martensite/austenite phase changes that are detectable by differential scanning calorimetry (DSC) and dynamic metal thermal analysis (DMTA) analysis over a large temperature range. For example, in some embodiments, there may be no martensite/austenite phase changes detectable by DSC and DMTA analysis in the range of about −60 degrees Celsius (° C.) to about 120° C. in the linear elastic and/or non-super-elastic nickel-titanium alloy. The mechanical bending properties of such material may therefore be generally inert to the effect of temperature over this very broad range of temperature. In some embodiments, the mechanical bending properties of the linear elastic and/or non-super-elastic nickel-titanium alloy at ambient or room temperature are substantially the same as the mechanical properties at body temperature, for example, in that they do not display a super-elastic plateau and/or flag region. In other words, across a broad temperature range, the linear elastic and/or non-super-elastic nickel-titanium alloy maintains its linear elastic and/or non-super-elastic characteristics and/or properties.
In some embodiments, the linear elastic and/or non-super-elastic nickel-titanium alloy may be in the range of about 50 to about 60 weight percent nickel, with the remainder being essentially titanium. In some embodiments, the composition is in the range of about 54 to about 57 weight percent nickel. One example of a suitable nickel-titanium alloy is FHP-NT alloy commercially available from Furukawa Techno Material Co. of Kanagawa, Japan. Some examples of nickel titanium alloys are disclosed in U.S. Pat. Nos. 5,238,004 and 6,508,803, which are incorporated herein by reference. Other suitable materials may include ULTANIUM™ (available from Neo-Metrics) and GUM METAL™ (available from Toyota). In some other embodiments, a superelastic alloy, for example a superelastic nitinol can be used to achieve desired properties.
In at least some embodiments, components of system 10 may also be doped with, made of, or otherwise include a radiopaque material. Radiopaque materials are understood to be materials capable of producing a relatively bright image on a fluoroscopy screen or another imaging technique during a medical procedure. This relatively bright image aids the user of system 10 in determining its location. Some examples of radiopaque materials can include, but are not limited to, gold, platinum, palladium, tantalum, tungsten alloy, polymer material loaded with a radiopaque filler, and the like. Additionally, other radiopaque marker bands and/or coils may also be incorporated into the design of system 10 to achieve the same result.
In some embodiments, a degree of Magnetic Resonance Imaging (MRI) compatibility is imparted into system 10. For example, components of system 10, or portions thereof, may be made of a material that does not substantially distort the image and create substantial artifacts (e.g., gaps in the image). Certain ferromagnetic materials, for example, may not be suitable because they may create artifacts in an MRI image. Components of system 10, or portions thereof, may also be made from a material that the MRI machine can image. Some materials that exhibit these characteristics include, for example, tungsten, cobalt-chromium-molybdenum alloys (e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nitinol, and the like, and others.
It should be understood that this disclosure is, in many respects, only illustrative. Changes may be made in details, particularly in matters of shape, size, and arrangement of steps without exceeding the scope of the disclosure. This may include, to the extent that it is appropriate, the use of any of the features of one example embodiment being used in other embodiments. The invention's scope is, of course, defined in the language in which the appended claims are expressed.
Various modifications and additions can be made to the exemplary embodiments discussed without departing from the scope of the present invention. For example, while the embodiments described above refer to particular features, the scope of this invention also includes embodiments having different combinations of features and embodiments that do not include all of the described features. Accordingly, the scope of the present invention is intended to embrace all such alternatives, modifications, and variations as fall within the scope of the claims, together with all equivalents thereof.
Claims
1. A catheter for use in cardiac mapping and/or ablation, the catheter comprising:
- an elongate catheter shaft having a distal ablation electrode region;
- an electrode assembly coupled to the distal ablation electrode region; and
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon.
2. The catheter of claim 1, wherein the distal ablation electrode region has an opening formed therein and wherein the electrode assembly extends through the opening.
3. The catheter of claim 1, wherein the electrode assembly includes a region that is disposed along a distal end of the distal ablation electrode region.
4. The catheter of claim 1, wherein the electrode assembly includes a plurality of arm regions and wherein each of the arm regions includes at least one electrode.
5. The catheter of claim 4, wherein the electrode assembly includes three or more arm regions.
6. The catheter of claim 4, wherein the electrode assembly includes four or more arm regions.
7. The catheter of claim 1, wherein the electrode assembly includes a mechanical locking end region that is capable of mechanically securing the electrode assembly to the distal ablation electrode region.
8. The catheter of claim 7, wherein the distal ablation electrode region has an opening formed therein and wherein the mechanical locking end region extends through the opening.
9. The catheter of claim 1, wherein the catheter shaft includes an inner channel, wherein the distal ablation electrode region includes a first opening and a second opening, and wherein the electrode assembly extends along the inner channel, through the first opening, along an outer surface of the distal ablation electrode region, and through the second opening.
10. The catheter of claim 1, wherein the electrode assembly is adhesively bonded to the distal ablation electrode region.
11. The catheter of claim 1, wherein the electrode assembly includes one or more electrode regions and one or more electrically insulated regions.
12. The catheter of claim 1, wherein the electrode assembly extends circumferentially around the distal ablation electrode region.
13. The catheter of claim 1, wherein the electrode assembly is designed to bow radially outward from the distal ablation electrode region.
14. The catheter of claim 1, wherein the distal ablation electrode region includes a platinum ablation tip electrode.
15. A method for manufacturing a medical device, the method comprising:
- inserting an electrode assembly into a channel formed within a distal ablation tip of a catheter;
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon;
- wherein the distal ablation tip includes a first opening and a second opening; and
- extending the electrode assembly extends through the first opening, along an outer surface of the distal ablation tip, and through the second opening.
16. A catheter for use in cardiac mapping and/or ablation, the catheter comprising:
- an elongate catheter shaft having an inner channel and a distal end region;
- a distal ablation tip capable of ablating tissue disposed at the distal end region;
- an electrode assembly coupled to the distal ablation tip;
- wherein the electrode assembly includes a flexible circuit having one or more electrodes disposed thereon;
- wherein the distal ablation electrode region includes a first opening and a second opening;
- wherein the electrode assembly extends along the inner channel, through the first opening, along an outer surface of the distal ablation tip, and through the second opening.
17. The catheter of claim 16, wherein the electrode assembly includes a region that is disposed along a distal end of the distal ablation tip.
18. The catheter of claim 16, wherein the electrode assembly includes a plurality of arm regions and wherein each of the arm regions includes at least one electrode.
19. The catheter of claim 16, wherein the electrode assembly includes a mechanical locking end region that is capable of mechanically securing the electrode assembly to the distal ablation tip.
20. The catheter of claim 19, wherein the mechanical locking end region extends through the first opening, the second opening, or both.
Type: Application
Filed: Mar 27, 2020
Publication Date: Jul 16, 2020
Inventors: Desmond Cheung (San Jose, CA), John C. Potosky (San Jose, CA), Andrew T. Marecki (Shrewsbury, MA), Isaac J. Kim (San Jose, CA), Mark D. Mirigian (San Jose, CA)
Application Number: 16/833,024