Method for preparing N-(carboxyethyl-p-aminophenol

- Mallinckrodt, Inc.

N-(2-carboxyethyl)-p-aminophenol is prepared by reacting p-aminophenol with at least an approximately equimolar proportion of a lower alkyl acrylate in a solvent for the reactants to form an N-(2-carbalkoxyethyl)-p-aminophenol, separating the N-(2-carbalkoxyethyl)-p-aminophenol, hydrolyzing it to form N-(2-carboxyethyl)-p-aminophenol and isolating the N-(2-carboxyethyl)-p-aminophenol substantially free of impurities.

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Description
Patent History
Patent number: T979003
Type: Grant
Filed: Feb 15, 1978
Date of Patent: Feb 6, 1979
Assignee: Mallinckrodt, Inc. (St. Louis, MO)
Inventor: Norman C. Jamieson (St. Louis County, MO)
Application Number: 5/877,914
Classifications
Current U.S. Class: Oxy (562/452)
International Classification: C07C 5100;