Patents Issued in June 30, 1992
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Patent number: 5126097Abstract: The present invention is related to the fluid flow sensing and switching device installed in an air-conditioning system, particularly in a heat exchanger, which has a hollow body or housing to accommodate a metallic sensing member with a pair of conductive terminals extending out thereof, while it is further sealed by resin. A ring member is slidably mounted with a pair of legs extending downwardly from the hollow body, which is positioned facing the fluid flow, so as to activate the metallic sensing means and further to control a compressor connected with the system.Type: GrantFiled: June 7, 1991Date of Patent: June 30, 1992Assignee: Yu Feng Enterprise Co., Ltd.Inventors: Kuo-Liang Weng, Kuo-Lianq Weng
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Patent number: 5126098Abstract: A method of removing bow in a nuclear fuel assembly is disclosed. The fuel assembly has top and bottom ends fittings and a plurality of longitudinally extending thimble tube members interconnecting top and bottom end fittings. At least two transverse fuel rod support grids are axially spaced along the thimble tube members. A plurality of fuel rods are transversely spaced and supported by the fuel rod support grids. In one embodiment, a weight of known magnitude is secured on the bottom end fitting and the fuel assembly is raised with the weight secured thereon so that the weight exerts a downward force on the fuel assembly for straightening the fuel assembly and eliminating compressive stresses within the fuel assembly. In another embodiment, the bottom end fitting is secured onto the upender used for transporting fuel assemblies into and out of the containment building and the fuel assembly is pulled for straightening the fuel assembly and eliminating compressive stresses within the fuel assembly.Type: GrantFiled: February 25, 1991Date of Patent: June 30, 1992Assignee: Westinghouse Electric Corp.Inventor: James A. Sparrow
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Patent number: 5126099Abstract: A nuclear energy plant housing a boiling water reactor utilizes an isolation condensers with nearly horizontal condenser tubes for both isolation condenser (IC) mode and passive containment cooling system (PCCS) mode, which is entered in response to a loss-of-coolant accident (LOCA). These tubes extend between a cylindrical distributor and a cylindrical collector. In either mode, the reactor vessel is coupled to the cylindrical distributor. Steam reaching the condenser is condensed to water, which flows back to the vessel, providing a cooling effect. In PCCS mode, gas exiting the tubes is trapped and diverted into a wet well. This diversion path is not avialable in IC mode. As a result water exits the tubes more slowly in IC modes in PCCS mode. The water remaining in the tubes during IC mode renders the condenser less efficient. This lower efficiency partially offsets the greater heat exchange in IC mode due to higher temperature differentials and the relatively absence of noncondensable gases.Type: GrantFiled: February 25, 1991Date of Patent: June 30, 1992Assignee: General Electric CompanyInventor: Rudolf M. Van Kuijk
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Patent number: 5126100Abstract: A unique and optimal method for assessing the feasibility of employing chemical decontamination processes to remove crud from nuclear reactor primary systems without adversely affecting the integrity of the system components or piping during further reactor operation is disclosed. Materials used to construct such components and piping are exposed to several cycles of simulated decontamination processing with a test loop constructed to simulate a range of full system decontamination process conditions. The material specimens are then removed and tested to assure that the particular decontamination processing system has no adverse effects on the materials used.Type: GrantFiled: December 26, 1990Date of Patent: June 30, 1992Assignee: Westinghouse Electric Corp.Inventors: Thomas G. Bengel, Gary J. Corpora, Robert M. Roidt, James S. Schlonski
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Patent number: 5126101Abstract: An apparatus for cleaning up reactor coolant includes a piping for taking out water in a reactor core, and this piping is provided separately from a primary loop recirculation piping and has its open end located at the bottom of a reactor pressure vessel. The taking-out piping extends upward from the open end within the reactor pressure vessel and extends through and outside of the side wall of the reactor pressure vessel. In a preferred form, the taking-out piping is provided near the highest position of its portion outside the reactor pressure vessel with a siphon brake valve.Type: GrantFiled: May 26, 1989Date of Patent: June 30, 1992Assignees: Hitachi, Ltd., Hitaching Engineering Co., Ltd.Inventors: Tadakazu Nakayama, Tomoko Sugi, Toshihisa Tsukiyama, Ryozo Tsuruoka, Shizuka Hirako
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Patent number: 5126102Abstract: The present invention is directed to a method of preparing a composite material excellent in joint strength and heat conductivity, and more specifically to a method of preparing a composite material composed of a high-melting material W and low-melting material Cu. The method comprising a first step of forming pores in the high-melting material W, to obtain a substrate material having a porosity distribution, with a high porosity at at least one region of the surface of the substrate material and the porosity gradually decreasing outward from the region; and a second step of impregnating the low melting material Cu to the substrate material obtained in the first step from the region of the highest porosity gradually downward. The substrate material being formed to have a gradient distribution of a composite ratio of the high-melting material and the low-melting material.Type: GrantFiled: March 12, 1991Date of Patent: June 30, 1992Assignee: Kabushiki Kaisha ToshibaInventors: Masashi Takahashi, Yoshiyasu Itoh
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Patent number: 5126103Abstract: The invention provides a process for modifying a ceramic and/or metallic porous material having open cells necessary for the material to serve the function of gas diffusing materials, filters or the like. The porous material is subjected to hot isostatic pressing at a temperature at which the base portion of the porous material softens or melts to compact or homogenize the base portion.Type: GrantFiled: April 8, 1991Date of Patent: June 30, 1992Assignee: Kabushiki Kaisha KobeseikoshoInventors: Kozo Ishizaki, Shojiro Okada, Takao Fujikawa, Atsushi Takata
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Patent number: 5126104Abstract: A method is disclosed for preparing an intimate mixture of powders of nickel-chromium-boron-silicon alloy, molybdenum metal powder, and Cr.sub.3 C.sub.2 /NiCr alloy suitable for thermal spray coatings which comprises milling a starting mixture of the above two alloys with molybdenum powder to produce a milled mixture wherein the average particle size is less than about 10 micrometers in diameter, forming an aqueous slurry of the resulting milled mixture and a binder which can be an ammoniacal molybdate compound or polyvinyl alcohol, and agglomerating the milled mixture and binder. The intimate mixture and binder may be sintered in a reducing atmosphere at a temperature of about 800.degree. C. to 950.degree. C. for a sufficient time to form a sintered partially alloyed mixture wherein the bulk density is greater than about 1.2 g/cc.Type: GrantFiled: June 6, 1991Date of Patent: June 30, 1992Assignee: GTE Products CorporationInventors: Vidhu Anand, Sanjay Sampath, David L. Houck, Jack E. Vanderpool
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Patent number: 5126105Abstract: Method and apparatus for forming an improved missile warhead comprising a cap section, a center section, and a mounting section, the three sections forming a tubular body closed by the cap section at one end thereof, with a plurality of cavities formed on the inner circumference of the center section. In formation of the cavity-bearing missile body, a missile body preform is isostatically formed from powder material along with low-density inclusions, the latter being removed during later processing to form an array of cavities, relying upon differential material densification for release of the inclusions from the pressed preform.Type: GrantFiled: May 14, 1991Date of Patent: June 30, 1992Assignee: Industrial Materials Technology, Inc.Inventors: Joseph C. Runkle, Timothy D. Howard
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Patent number: 5126106Abstract: A chromium weld material comprising chromium as a main component and either one of or an appropriate combination of elements selected from the group IVb metals of the periodic table, Al, metals belonging to the groups VIIb, VIII, and Ib of the periodic table, Nb, and Ta and, if desired, at least one of rare earth elements, a chromium rolled article comprising chromium as a main component and either one of or an appropriate combination of elements selected from Al, Ti, Zr, Hf, Y, rare earth elements, and elements belonging to the groups Vb, VIb, and VIIb of the periodic table, and a process for producing said rolled article by cross-rolling under specific temperature and output rate conditions are disclosed. The weld material provides a weld free from deterioration of mechanical characteristics. The rolled article exhibits excellent tensile characteristics. The process provides a rolled sheet of small thickness without causing craking.Type: GrantFiled: May 22, 1990Date of Patent: June 30, 1992Assignee: Tosoh CorporationInventors: Hiroaki Hidaka, Tsutomu Kuniya, Koichi Hanawa, Tomoyuki Oikawa
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Patent number: 5126107Abstract: An iron, nickel-, chromium base alloy having an austenitic structure, good high temperature features, including a very high resistance to oxidization in an oxidizing atmosphere and to carburization in a carborizing atmosphere at high temperatures, and a high creep fracture resistance. The alloy has the following composition in weight percent: 0.01-0.08 carbon, 1.2-2.0 silicon, from traces up to 2 manganese, 22-29 chromium, 32-38 nickel, 0.01-0.15 rare earth metals, 0.08-0.25 nitrogen, with the balance essentially of only iron and unavoidable impurities and normally occurring accessory elements in normal amounts. The rare earth metals in combination with the silicon content serve to improve the growth of a protecting silicon dioxide-layer on the metal surface, when the metal surface is subjected to high temperatures in oxidizing atmospheres. This counteracts the transportation of metal irons, in particular chromium, out of the alloy so that scaling is minimized.Type: GrantFiled: April 10, 1991Date of Patent: June 30, 1992Assignee: Avesta AktiebolagInventor: Sven Darnfors
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Patent number: 5126108Abstract: Aminophosphonate-containing polymers of the formula:--B].sub.m [A].sub.nwhereinA represents repeating units from one or more ethylenically unsaturated comonomers;B is ##STR1## wherein R is hydrogen or methyl.X is hydrogen or an alkali metal,Z is CH.sub.2 --P(O)(OX).sub.2 or C.sub.1 -C.sub.6 alkyl, aryl, cyclohexyl or alkaryl,m/n is 0.1 to .5.The novel polymers of the present invention may be used as dispersants for concentrated aqueous particulate slurries, and as corrosion inhibitors and scale inhibitors in water treatment.Type: GrantFiled: February 27, 1991Date of Patent: June 30, 1992Assignee: National Starch and Chemical Investment Holding CorporationInventors: John C. Leighton, Carmine P. Iovine
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Patent number: 5126109Abstract: A preserving material of a layered structure which is composed of an impregnated absorbent sheet containing a preserving liquid and impermeable barrier films being bonded to both surfaces of the adsorbent sheet. The effective components of the preserving liquid is evaporated gradually from the peripheral edges of the preserving material.Type: GrantFiled: April 30, 1991Date of Patent: June 30, 1992Assignee: Nippon Petrochemicals Company, LimitedInventor: Hachiro Saitoh
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Patent number: 5126111Abstract: A method of removing, reducing or detoxifying organic pollutants from a fluid, water or air, by contacting the fluid with a photoreactive metal semiconductor material in the presence of ultraviolet light of a wavelength to activate the photoreactive material, is improved by simultaneously contacting the photoreactive material with a substance that accepts electrons and thus inhibits hole-electron recombination. Such substance will be such as to readily accept electrons either from the conduction band or from superoxide ions, and to rapidly dissociate into harmless products.Type: GrantFiled: May 20, 1991Date of Patent: June 30, 1992Assignee: Nutech Energy Systems Inc.Inventors: Hussain Al-Ekabi, Robert B. Henderson
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Patent number: 5126112Abstract: The present invention relates to an insulation system for a high temperature reactor in which chlorosilanes and hydrogen gases are present. The system described comprises an inner graphite radiant heat shield and an outer carbon-based, rigid, felt insulation of high density. The inner radient heat shield provides increased chemical stability at the hot face in a chlorosilane and hydrogen reactor. Also, the inner radient heat shield reduces the temperature at the interface with the carbon-based rigid felt, thereby reducing the reactivity of the chlorosilanes with the carbon-based rigid felt. The high density of the carbon-based rigid belt further reduces radiant heat loss. More importantly, the high density of the carbon-based rigid felt excludes the highly heat conductive hydrogen gas from the voids of the flet. The insulation system, as described, allows reactors containing chlorosilanes and hydrogen gases to be operated at higher and more efficient temperatures for longer periods of time.Type: GrantFiled: February 7, 1991Date of Patent: June 30, 1992Assignee: Hemlock Semiconductor CorporationInventor: Richard A. Burgie
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Patent number: 5126113Abstract: An apparatus for producing a single crystal ingot grown by the Czochralski method includes a plurality of grip arms each having a grip finger engageable with a downwardly facing engagement step formed on an upper part of the single crystal, and a ring slidably fitted around a plurality of grip arms to hold the grip arms in a closed position in which the engagement step of the single crystal is firmly gripped by the grip fingers against detachment. The apparatus having such a ring is particularly advantageous when used for the production of a heavy single crystal ingot in which the grip arms are forced to spread apart by the weight of the single crystal ingot.Type: GrantFiled: March 29, 1991Date of Patent: June 30, 1992Assignee: Shin-Etsu Handotai Co., Ltd.Inventors: Hirotoshi Yamagishi, Kouji Mizuishi, Fumihiko Hasegawa
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Patent number: 5126114Abstract: According to the present invention, the inside of a crucible in which a molten raw material is placed is partitioned off with a partition ring so that a pulled single crystal is surrounded and the molten raw material may be moved and granular silicon is supplied to the outside of the partition ring, thereby to form the whole surface of outside molten liquid as a granular silicon soluble region so as to maintain the molten liquid surface on the inside of the partition ring at almost a constant level, and also to set the temperature of the molten liquid on the outside of the partition ring higher than the temperature of the inside thereof at least by 10.degree. C. or higher by covering the partition ring and the molten liquid surface on the outside thereof with a heat keeping board.Type: GrantFiled: January 3, 1990Date of Patent: June 30, 1992Assignee: NKK CorporationInventors: Hiroshi Kamio, Kenji Araki, Yoshinobu Shima, Makoto Suzuki, Akira Kazama, Shigetake Horie, Yasumitsu Nakahama
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Patent number: 5126115Abstract: A process for the preparation of a single crystal of a biopolymer by growth from a solution, which comprises continuously changing one factor having an influence on the conditions for crystallization of a solution of a biopolymer, fractionating the solution, and independently crystallizing the resultant fractions. The process may be carried out by an apparatus comprising a means for feeding a crystallizing agent solution, a means for feeding a biopolymer solution, a means for producing a series of changes of predetermined crystallization conditions, said means continuously changing at least one factor having an influence on the conditions for crystallization of the biopolymer solution, and means for fractionating the solution and independently crystallizing the resultant fractions.Type: GrantFiled: October 30, 1990Date of Patent: June 30, 1992Assignee: Fujitsu LimitedInventors: Shozo Fujita, Koji Asano, Takafumi Hashitani
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Patent number: 5126116Abstract: The invention provides a method of forming copper arsenate. Copper and arsenic are leached into a treatment solution maintained at a pH level of about 2 to 5 in the presence of at least one impurity. An oxidant is added to the treatment solution to oxidize the copper and arsenic. A copper arsenate compound is precipitated from the solution as copper arsenate. Preferably, the copper arsenate is then releached in a purification solution. The molar ratio of copper to arsenic is adjusted to a level of at least 2. The pH of the purification solution is then increased to precipitate copper arsenate having a decreased concentration of said at least one impurity. Impure copper arsenate may be suspended and reacted in a recrystallization solution preferably having cupric ion. The pH of recrystallization solution is adjusted to a valve between about 1 and 4.5.Type: GrantFiled: June 17, 1991Date of Patent: June 30, 1992Assignee: Inco LimitedInventors: Eberhard Krause, Vladimir J. Zatka, Steven W. Laundry
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Patent number: 5126117Abstract: A system for containing and detoxifying a gaseous stream, comprising a storage housing containing one or more sources of toxic gas, means for applying negative pressure to the storage housing to continuously exhaust a gaseous stream therefrom, and a treatment housing interposed in the gaseous stream, the treatment housing containing one or more layers of solid sorbent material capable of removing the toxic gas from the stream, wherein a flow of treated gas that exits the treatment unit may be safely released to the environment.Type: GrantFiled: May 22, 1990Date of Patent: June 30, 1992Assignee: Custom Engineered Materials, Inc.Inventors: John C. Schumacher, Lawrence B. Anderson, Timothy E. Hammon
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Patent number: 5126118Abstract: A method and apparatus including a reaction chamber interposed in a polyvalent metal redox solution flow path between an absorber chamber and an oxygenation chamber, including one or more oxygenation stages, for contact in the reaction chamber of H.sub.2 S-laden catalytic polyvalent metal redox solution form the absorber chamber with highly oxidized polyvalent metal redox solution from the last oxygenation stage to accomplish oxidation of the dissolved H.sub.2 S species by interaction with the oxidized redox catalyst essentially in the absence of gaseous dissolved oxygen. The highly oxidized polyvalent metal redox solution, including Fe.sup.+3 or V.sup.+5, contacts the H.sub.2 S-laden solution from the absorber chamber for reoxidation of the dissolved HS.sup.-, S.sup.= and any of the polyvalent metal sulfur compounds (presumably a chelated iron sulfide or a vanadium sulfide), to avoid formation of sulfate or thiosulfate salts which reduce the yeild of sulfur and build up in the solution.Type: GrantFiled: April 8, 1991Date of Patent: June 30, 1992Assignee: ARI Technologies, Inc.Inventor: Leslie C. Hardison
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Patent number: 5126119Abstract: A process for producing a chlorine-free hydrochloric acid low in AOX from crude gases containing hydrogen chloride and organic impurities has been found. The crude gases wer subjected to a thermal treatment at 800.degree. to 1600.degree. in a reducing atmosphere. The hydrochloric acid obtained after absorption of the hydrogen chloride is chlorine-free and contains virtually no organic impurities. The waste gas is also chlorine-free.Type: GrantFiled: April 1, 1991Date of Patent: June 30, 1992Assignee: Hoechst AktiengesellschaftInventors: Walter Freyer, Theo Olffers
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Patent number: 5126120Abstract: This invention relates to zinc phosphate molecular sieves. These molecular sieves have a three-dimenisonal microporous framework structure of ZnO.sub.2 and PO.sub.2 tetrahedral units, an intracrystalline pore system and an empirical chemical composition on an anhydrous basis expressed as ratio of the oxides by the formula: rM.sub.2 O:sZnO:P.sub.2 O.sub.5, where M is at least one alkali metal, r ranges from about 0.9 to about 1.5 and s ranges from about 1.8 to about 3.0. These molecular sieves may be prepared by hydrothermal crystallization of a reaction mixture prepared by combining a reactive source of phosphorus, zinc, at least one alkali metal and water. This invention also relates to processes using these molecular sieves.Type: GrantFiled: January 23, 1991Date of Patent: June 30, 1992Assignee: UOPInventor: Robert L. Bedard
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Patent number: 5126121Abstract: Rapidly heat powdered aluminum in the presence of a source of nitrogen at a temperature of 1873 to 2373 K. to produce aluminum nitride, then promptly quench the aluminum nitride product. The product has a surface area between 2 and 8 square meters per gram and an oxygen content of less than 1.2 weight percent.Type: GrantFiled: May 3, 1991Date of Patent: June 30, 1992Assignee: The Dow Chemical CompanyInventors: Alan W. Weimer, John P. Henley, Gene A. Cochran, Glenn A. Eisman, William G. Moore
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Patent number: 5126122Abstract: This composition is made up of an injectable aqueous solution of a glycoprotein, hyalurenectin, onto which a radioactive element is bound.Type: GrantFiled: August 3, 1990Date of Patent: June 30, 1992Assignee: University de RouenInventors: Jean Chomant, Marie-Noelle Courel, Bertrand Delpech, Nicole Girard
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Patent number: 5126123Abstract: This invention relates to aerosol inhalation drug formulations comprising one or more drugs and one or more soluble surfactants in propellant 134a.Type: GrantFiled: February 1, 1991Date of Patent: June 30, 1992Assignee: Glaxo, Inc.Inventor: Keith A. Johnson
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Patent number: 5126124Abstract: A hair spray resin compositon is provided herein which is capable of delivering a fine finishing mist at a high resin solids level. The composition is substantially moisture resistant, provides a stiff resin film having excellent hair holding power, and has a relatively low concentration of volatile organic compounds therein. The composition of the invention attains its unique attributes by including a predetermined blend of at least two hair spray resins, one being a relatively high molecular weight resin, and the other resin having a relatively low molecular weight. The latter resin is present in the composition in a substantially greater proportion than the higher molecular weight resin.Type: GrantFiled: April 8, 1991Date of Patent: June 30, 1992Assignee: ISP Investments Inc.Inventors: Mohammed Tazi, Stephen L. Shernov, Edward W. Walls, Jr., Robert B. Login
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Patent number: 5126125Abstract: A method of decreasing the melanin content in mammalian skin and hair by administering to a mammal a composition comprising an effective amount of one or more derivatives of 5,6-dihydroxyindole, the derivatives having one or more substituents which are capable of being removed enzymatically, in admixture with a pharmaceutically acceptable carrier, the amount being 0.5% to 20% wt/wt based on the composition.Type: GrantFiled: October 6, 1989Date of Patent: June 30, 1992Assignee: Yale UniversityInventor: John M. Pawelek
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Patent number: 5126126Abstract: A hair treating composition is disclosed which is a mixture of a film forming material and a solvent for the film forming material. The film forming material is an aminofunctional silicone resin formed by reacting a cyclic silylamine and a silicone resin. A hair treating method for imparting curl retention to hair employing the resin as the film forming material is described.Type: GrantFiled: November 20, 1990Date of Patent: June 30, 1992Assignee: Dow Corning CorporationInventors: Padmakumari J. Varaprath, Judith M. Vincent
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Patent number: 5126127Abstract: Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available iodine and an alkalinizing agent in an effective amount to maintain the stability of the solution for a desired shelf-life of the solution when said solution is stored in a substantially nonpermeable container, the solution being non-buffered. In preferred embodiments, the iodophor solution is a microbicidal PVP-I solution for ophthalmic use.Type: GrantFiled: July 16, 1991Date of Patent: June 30, 1992Assignee: Euroceltique, S.A.Inventors: Dileep Bhagwat, Benjamin Oshlack
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Patent number: 5126128Abstract: Periplanone-B analogue of (4E, 8R, 9R, 10R)-8,9-epoxy-5-methyl-10,10-methylene-oxy-4-cyclodecen-1-one, suitable as cockroach attractant can be prepared by reacting 6-methyl-2,6-cyclodecadien-1-one with a silylating reagent under the presence of a basic catalyst to form a silyldienol ether, reacting the resultant ether with an organic peracid to obtain (2Z, 6E)-10-hydroxy-6-methyl-2,6-cyclodecadien-1-one, reacting the resultant product with a peroxide under the presence of a basic catalyst after protecting hydroxy groups thereof with protection groups to obtain an epoxide, reacting the epoxide with chloromethyl lithium or dimethyl sulfonium methylide thereby introducing a spiroepoxy group and then removing the protection groups, to obtain (1S, 4E, 8R, 9R, 10S)-8,9-epoxy-5-methyl-10,10-methyleneoxy-4-cyclodecen-1-ol and, further, oxidizing the resultant product with a chromic acid type or dimethyl sulfoxide type oxidizing agents.Type: GrantFiled: October 16, 1990Date of Patent: June 30, 1992Assignee: Japan Tobacco Inc.Inventors: Masataka Mori, Kentaro Okada, Kazuko Shimazaki, Tatsuji Chuman
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Patent number: 5126129Abstract: Treatment of Cancer with Flavones and Interleukin 2.Type: GrantFiled: February 4, 1991Date of Patent: June 30, 1992Assignee: The Government of the United States of America as represented by the Secretary of the Department of Health & Human ServicesInventors: Robert H. Wiltrout, Ronald Hornung
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Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein A
Patent number: 5126130Abstract: The present invention is directed to a composition containing a first monoclonal antibody, capable of neutralizing human cytomegalovirus (HCMV), that binds to a first epitope on HCMV GCA, and a second non-neutralizing HCMV monoclonal antibody that binds to a second epitope on HCMV GCA. The GCA complex includes antigenically-related glycoproteins of molecular weights 130,000, 93,000, and 50,000-52,000 kDa. The mixture of the two antibodies has greater neutralizing activity than a composition containing the first antibody alone. Also provided is a method for neutralizing the infectivity of HCMV using the composition.Type: GrantFiled: August 7, 1987Date of Patent: June 30, 1992Assignee: The Childrens Hospital IncorporatedInventors: Nancy O. Lussenhop, Bruce E. Kari, Richard C. Gehrz -
Patent number: 5126131Abstract: Undesired immune responses are suppressed by administering a nonimmunogenic material which comprises one or more haptens or epitopes corresponding to the antigen which causes the undesired immune response, the number and spacing of the haptens or epitopes being insufficient to trigger an immune response but sufficient to inhibit it. Also disclosed is an improved vaccine from which low molecular weight suppressive polymer has been removed.Type: GrantFiled: September 21, 1988Date of Patent: June 30, 1992Assignee: The Johns Hopkins UniversityInventors: Howard M. Dintzis, Renee Z. Dintzis
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Patent number: 5126132Abstract: A new immunotherapeutic method of treating cancer with a combination of tumor infiltrating lymphocytes and IL-2 has been described.Type: GrantFiled: August 21, 1989Date of Patent: June 30, 1992Assignee: The United States of America as represented by the Department of Health and Human ServicesInventor: Steven A. Rosenberg
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Patent number: 5126133Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.Type: GrantFiled: June 27, 1989Date of Patent: June 30, 1992Assignee: Mycogen CorporationInventors: Jewel Payne, August J. Sick
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Patent number: 5126134Abstract: There is provided a pharmaceutical composition comprising as component A a plasminogen activator and as component B hirudin together with a pharmaceutically acceptable carrier. The pharmaceutical composition can be used for the prophylaxis and therapy of thrombosis or diseases caused by thrombosis.Type: GrantFiled: September 18, 1989Date of Patent: June 30, 1992Assignees: Ciba-Geigy Corporation, UCP Gen-Pharma AGInventors: Jutta Heim, Giancarlo Agnelli, Czeslaw Czendlik
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Patent number: 5126135Abstract: The present invention relates to a dermatological composition composed for cosmetics or medicines for external application to skin and to oral or nasal mucous-membrane. This composition can be applied in particular in the cosmetic or pharmaceutical field, especially in the dermatological cases to regenerate and to revitalize damaged cells by equilibrating electrochemical ion gradients across cell membrane and also by osmotic pressure on the inner face of the cell membrane. A composition based on a water phase in accordence with present invention comprises dextran, glucose, mutan lentinan, NaCl, KCl, and CaCl.sub.2, which are dissolved in the aqueous phase.Type: GrantFiled: June 18, 1991Date of Patent: June 30, 1992Assignee: Japan Fine Chemical Co., Ltd.Inventors: Hajime Yamada, Akira Yamada
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Patent number: 5126136Abstract: A skin protection lotion consisting of a water phase mixture and an oil phase mixture. The two mixtures are mixed together to form a lotion concentrate. The lotion concentrate may be aerosolized in a can that then dispenses a mousse. Either the lotion or the mousse may be applied to an area of skin, such as the hands, to form a thin protective coating that protects the skin from a wide range of hazardous fluids.Type: GrantFiled: May 16, 1991Date of Patent: June 30, 1992Inventors: Pierre H. Merat, Ralph Akyuz
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Patent number: 5126137Abstract: The small animal prophylactic dentifrice is a foam figure 10 jacketed by a minimally fine threaded netting 14 which, in concert with a flavor attractant, both encourages and results in positive dental care results for small animals.Type: GrantFiled: June 12, 1990Date of Patent: June 30, 1992Inventor: William S. Lambert
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Patent number: 5126138Abstract: A method of making the surface of a fluorochemically treated substrate antimicrobially active by exposing the fluorochemically treated substrate to a compound selected from the group consisting of inorganic acids and organic acids. Exemplary of the acids are sulfuric, hydrofluoric, hydrochloric, hydrobromic, hydriodic, nitric, perchloric, phosphoric, boric, acetic, adipic, anisic, benzoic, butyric, fumaric, gallic, glutaric, glycolic, lactic, lauric, tannic, and tartaric acids.Type: GrantFiled: July 19, 1988Date of Patent: June 30, 1992Assignee: Dow Corning CorporationInventors: James B. McGee, Kelly L. Benjamin
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Patent number: 5126139Abstract: A paste insecticide bait to be contained in a pressurized container, for dispensing a semi-solid bead of bait in cracks, crevices and the like for destroying insects, in particular cockroaches, said composition comprising an oil-in-water emulsion of a pentadienone toxicant/fatty acid mixture in a corn syrup solution, together with oatmeal and, optionally, titanium oxide.Type: GrantFiled: December 12, 1990Date of Patent: June 30, 1992Assignee: The Clorox CompanyInventor: Daniel C. Geary
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Patent number: 5126140Abstract: Disclosed is a biocompatible, thromboresistant substance useful for implantable and extracorporeal devices in contact with the vascular system, and methods for producing the same. The biocompatible, thromboresistant substance comprises a synthetic, biocompatible material, at least one biocompatible base coat layer adhered to at least one surface of the material, and the thrombogenesis inhibitor thrombomodulin immobilized on the base coat layer via a component capable of binding the inhibitor without affecting its thrombogenesis-inhibiting activity.Type: GrantFiled: July 24, 1989Date of Patent: June 30, 1992Assignee: New England Deaconess Hospital CorporationInventors: Ralph K. Ito, Frank W. LoGerfo
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Patent number: 5126141Abstract: A process and compositons for reducing post-surgical adhesion formation/reformation in mammals following injury to organs situated in mammalian body spaces. Aqueous, thermally reversible gel compositions, preferably at mammalian body fluid pH, comprising a polyoxyalkylene polymer and an ionic polysaccharide are applied to injured areas of the organs situated in body cavities such as, the peritoneal, pelvic, or pleural cavity. The aqueous gels are rendered thermally irreversible upon contact with a counter-ion.Type: GrantFiled: August 10, 1990Date of Patent: June 30, 1992Assignee: Mediventures IncorporatedInventor: Raymond L. Henry
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Patent number: 5126142Abstract: A dispenser is disclosed for delivering a beneficial ionophore to an animal. The dispenser comprises (1) a semipermeable housing defining an internal space, (2) at least one composition comprising an ionophore and a pharmaceutically acceptable carrier in the space, (3) an expandable hydrophilic composition in the space, (4) a dense member in the space, and (5) at least one exit passageway in the housing for delivering the ionophore from the dispenser.Type: GrantFiled: January 11, 1991Date of Patent: June 30, 1992Assignee: ALZA CorporationInventors: Atul D. Ayer, Terry L. Burkoth, Anthony L. Kuczynski, Joseph C. Deters
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Patent number: 5126143Abstract: Bowel movement-improving food products incorporating dietary fibers in total amount of 10 to 50% by weight based on the whole products, said dietary fibers comprising hardly water-soluble dietary fibers and readily water-soluble dietary fibers at a ratio of 1:2-30 parts by weight and 10% by weight or more of the former being hemicellulose. The food products of the invention are useful for preventing and treating constipation of both proctosenous and colonic types.Type: GrantFiled: December 6, 1989Date of Patent: June 30, 1992Assignee: Terumo Kabushiki KaishaInventors: Hiroshi Nakashima, Takuji Gotoh
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Patent number: 5126144Abstract: The invention relates to an apparatus for the controlled delivery or release of nitroglycerin to the human or animal skin, preferably in plaster form with a nitroglycerin-impermeable backing layer, a one or multiple-part reservoir containing a pressure sensitive adhesive nitroglycerin in uniform or irregular distribution and optionally a removable protective layer impermeable for nitroglycerin, the reservoir being produced using hol melt pressure sensitive adhesives with a processing temperature of 40.degree. to 80.degree. C., preferably 40.degree. to 60.degree. C. and in particularly preferred manner 40.degree. to 45.degree. C., a process for the production thereof and the use of the apparatus for therapeutic purposes in human and veterinary medicine.Type: GrantFiled: August 10, 1990Date of Patent: June 30, 1992Assignee: LTS Lohmann Therapie-Systems GmbH & Co. KGInventors: Halvor Jaeger, Hans-Rainer Hoffmann, Reinhold Meconi, Robert-Peter Klein
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Patent number: 5126145Abstract: A sustained or controlled release tablet is disclosed. The tablet comprises a water soluble medicament, a hydroxypropyl methylcellulose having sustaining action, a pharmaceutical binding agent, and a hydrophobic component.Type: GrantFiled: June 11, 1990Date of Patent: June 30, 1992Inventors: Kenneth L. Evenstad, Kuldip R. Malhotra, Victoria A. O'Neill
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Patent number: 5126146Abstract: A microporous, cellulosic coating useful in combination with osmotically controlled drug delivery devices is disclosed. In one embodiment, this coating results from application to core tablets of a coating dispersion comprised of a synthetic latex formed by emulsification of cellulosic polymers stabilized by surfactants, containing a water-soluble pore forming agent and a plasticizer.Type: GrantFiled: October 23, 1989Date of Patent: June 30, 1992Assignee: Merck & Co., Inc.Inventors: Leah A. Seminoff, Gaylen M. Zentner
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Patent number: 5126147Abstract: A multiphasic sustained release injectable delivery system is provided, as well as a method for treating humans and other mammals with that multiphasic sustained release system.Type: GrantFiled: February 8, 1990Date of Patent: June 30, 1992Assignee: BioSearch, Inc.Inventors: Loui J. Silvestri, H. Ruth Pyle