Abstract: Liquid deicing and anti-icing compositions are provided by aqueous solutions of (a) alkali metal acetates, e.g., KAc or NaAc, (b) phosphate ion, e.g., K.sub.3 PO.sub.4, and (c) soluble silicate, e.g., K.sub.2 SiO.sub.3 or Na.sub.2 SiO.sub.3. These compositions are environmentally safe and meet FAA standards for metal corrosion resistance. They are effective at very low temperatures, e.g. -40.degree. F., and provide particularly effective deicing compositions when used in combination with granular CMA.

Abstract: To replace cleaning compositions based on 1,1,2-trichloro-1,2,2-trifluoroethane (F113), the invention provides a composition comprising, by weight, 30 to 69% 1,1,1,3,3-pentafluorobutane (F365-mfc), 30 to 60% methylene chloride and 1 to 10% methanol. These three compounds form a positive azeotrope (B.p.=32.1.degree. C. at normal pressure).The composition, optionally stabilized, can be used for the cleaning and/or the drying of solid surfaces, in particular for removing flux from printed circuits and for degreasing mechanical components.

Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds of positive dielectric anisotropy, characterized in that it contains one or more compounds of the general formula I ##STR1## in which X is fluorine, chlorine, CF.sub.3, OCF.sub.3 or OCHF.sub.2, and R is alkyl, oxaalkyl, fluoroalkyl or alkenyl, in each case having up to 7 carbon atoms.

Abstract: A composition for controlling the deposition of scale imparting species on the structural surfaces of steam generating systems comprising the use of a water soluble polymer having the structure ##STR1## wherein R.sub.1 is H or lower (C.sub.1 14 C.sub.4) alkyl, R.sub.2 is (CH.sub.2 --CH.sub.2 --O).sub.n, ##STR2## or a mixture of both, and n is an integer of from about 1 to about 40, R.sub.3 is H, lower (C.sub.1-C.sub.4) alkyl or an acetate. This polymer may also be used in concert with topping agents such as phosphoric acids, phosphonic acids, amines, metal chelating agents and oxygen scavengers.

Abstract: A liquid crystal display device comprising a pair of substrates each having transparent electrodes over the surface thereof and an orientation film over the electrode, and a liquid crystal interposed between the pair of substrates, the liquid crystal being a ferroelectric liquid crystal composition having incorporated therein a conjugated cyano compound or conjugated halogen compound serving as an electron acceptor.

Abstract: This invention provides a high polymer having the following repeating unit (I), a diene compound which is represented by the following formula (II) and is a raw material of the high polymer: ##STR1## and a ferroelectric liquid-crystalline composition containing the high polymer and a low molecular weight smectic liquid-crystalline compound. The ferroelectric liquid-crystalline composition is easy to orient and exhibits a fast response against applied electric field.

Abstract: The present invention relates to an alignment treating agent for a liquid crystal cell, which comprises an organic solvent-soluble polyimide resin comprising a tetracarboxylic acid and a diamine, at least 10 mol % of the diamine having a bivalent organic group selected from the group consisting of: ##STR1## The aligned film for a liquid crystal using the solvent-soluble polyimide resin of the present invention does not require a heat treatment at a high temperature at the time of forming a resin film and enables to use a substrate poor in heat-resistance, and alignment properties such as a tilt angle and a voltage maintenance of the aligned film are not deteriorated even after durability test at a high temperature.

Abstract: Metal phosphide used as a raw material in the synthesis of alkaline earth metal halophosphate phosphor activated by antimony and manganese acts as a reducing agent to prevent oxidation of the antimony and manganese. The result is maximum availability of trivalent antimony and divalent manganese for incorporation into the phosphor lattice.

Abstract: Detergent compositions comprising nonionic detergent surfactant; hydrophobic cleaning solvent; and suds control system comprising fatty acid and anionic sulfonated and/or sulfated detergent surfactant. The compositions are preferably in the form of aqueous liquids and preferably have monoethanolamine and/or beta-aminoalkanol present.

Abstract: By using AVLIS or other methods capable of providing a depleted isotopic mixture, troublesome isotopes such as Gd.sup.154, Gd.sup.156 and Er.sup.166 are selectively removed from naturally occurring isotopic mixtures, while avoiding the additional costs associated with complete fractionation of the mixture. Such mixtures can be used to provide a burnable nuclear fuel absorber having a selectively depleted isotope or isotopes. In particular, the invention concerns burnable absorbers containing erbium with a depleted 166 isotope, gadolinium with a depleted 156 isotope or with depleted 154 and 156 isotopes, and methods for making such absorbers.

Abstract: A method and apparatus for aerating an aqueous solution is disclosed comprising a vortex cylinder for receiving an aqueous solution stream under pressure. The aqueous solution stream is tangentially injected into the vortex cylinder forming a descending swirling vortex of aqueous solution. The swirling vortex develops a negative pressure zone for drawing air into the vortex through an air intake tube open to ambient pressure. The air and aqueous solution are mixed in a mixing chamber for supersaturating the aqueous solution with dissolved oxygen.

Abstract: A method for the preparation of a cross-linked, rigid, polyethylene, foam sheet product, which method comprises heating at least one surface of a cross-linked, polyethylene, foam sheet material, to a temperature sufficient to cause a slight surface post-expansion of the foam sheet material, contacting the heated, post-expanded, foam surface with a cold metal element, to form a cross-linked, polyethylene, foam sheet product of the desired, accurate thickness, or having a desired three-dimensional design on the cross-linked, foam sheet material.

Abstract: A method of making a fiber-reinforced ceramic matrix composite of complex shape by first rigidifying a fibrous arrangement made of woven or braided material by impregnating with a preceramic resin, and then curing and pyrolyzing the resin to form a rigid or stiff preform. The rigid preform is then densified by chemical vapor infiltration, e.g., using a forced-flow/thermal-gradient process. Using three-dimensional woven fabrics made of ceramic fibers, such as silicon carbide or silicon nitride, strong high-temperature resistant composites are produced having porosities from about 20 percent to less than about 5 percent.

Abstract: Upon setting various molding conditions relating to new molding, one or more than two of pseudo-correlation data Q1, Q2, Q3, Q4, Q5 . . . which are secondary physical values (a fluid pressure, a hold pressure, a pressure coefficient and the like) previously set in accordance with primary physical values (a thickness, a fluid length and the like) relating to a virtual molded article, and upon setting of the molding conditions, the molding conditions are computed from primary physical values relating to molding of an actual molded article in accordance with the correlation data Q1 . . . , the molding conditions including a design condition for dies or a result of analysis of operation.

Abstract: An expert system for retrieving molding conditions, in which a statistical technique is added to the functions of the conventional expert system, causes of defects are inferred from the records of countermeasures taken and inputted defect occurrence situation, conditions for temporary molding are obtained while repeating test molding, qualitative defects are extracted from defects occurred, a boundary of a region in which defects occur is determined with decision analysis of qualitative defects extracted with the use of the record of countermeasures as above, a condition for molding to eliminate the qualitative defects is determined on the basis of the boundary of region of defects occurrence, quantitative defects are extracted from defects occurred, and molding conditions for eliminating the quantitative defects are determined by performing analysis of variance depending on design of experiment with the quantitative defects extracted from the record of countermeasures, whereby the frequency of experiment is

Abstract: A method of making two-layer tablets or pellets in a twin rotor pressing machine, in which method during a normal manufacturing period powdery or particulate material is fed into die bores of a die rotor so as to form first layers, said first layers are compressed in a first step by plungers synchronously rotating with the die rotor so as to form first layer pressed articles, the two layers within the die bores are compressed in a second step by said plungers so as to obtain two-layer tablets or pellets, and said two-layer tablets or pellets are removed at a main discharge station, and in which method during an inspection period first layer pressed articles removed at an intermediate discharge station or two-layer tablets or pellets removed at said main discharge station are fed to an inspection station, characterized in that during the inspection period said first layers are compressed more than in said first step during the normal manufacturing period before samples thereof are withdrawn at said intermediat

Abstract: Cementitious compositions useful as lightweight aggregates are formed from a blend of spent bed material from fluidized bed combustion and fly ash. The proportions of the blend are chosen so that ensuing reactions eliminate undesirable constituents. The blend is then mixed with water and formed into a shaped article. The shaped article is preferably either a pellet or a "brick" shape that is later crushed. The shaped articles are cured at ambient temperature while saturated with water. It has been found that if used sufficiently, the resulting aggregate will exhibit minimal dimensional change over time. The aggregate can be certified by also forming standardized test shapes, e.g., cylinders while forming the shaped articles and measuring the properties of the test shapes using standardized techniques including X-ray diffraction.

Abstract: A method of production of a plastic laminate having a protective layer on a foamed layer comprising coating plastisol containing a vinyl chloride resin or an acrylic resin having epoxy group and having average particle diameter of 0.05 to 5 mm and plasticizer as the essential components on the surface of vinyl chloride resin layer containing an organic foaming agent, then forming the combined layers by heating and foaming is provided. A plastic laminate having a protective layer of polyvinyl chloride having excellent surface strength, abrasion resistance and resistance to chemicals on a foamed layer can be produced efficiently.

Abstract: A ceramic firing method particularly suitable for the fabrication of metallic oxide varistor bodies containing a major proportion of zinc oxide and a minor proportion of antimony oxide. Should moldings of this composition be fired in direct contact with a conventional molding stand, antimony oxide would diffuse readily into the stand, with the consequent creation of varistor bodies that are unsatisfactory in their surge withstanding capability. Therefore, in order to avoid such effluence of antimony oxide or like diffusible metallic oxide, the moldings are fired on a diffusion retarder which preferably is of substantially the same composition as the moldings, only with a higher proportion of the diffusible substance. The diffusion retarder may take the form of either flat overlays or loose particles of sintered ceramic material, both placed on the conventional molding stand.

Abstract: A batch method for preparing polyacrylamide aqueous gels for electrophoresis, including providing a plurality of gel plate supporters abreast in an airtight gel-forming container, eliminating oxygen from or introducing oxygen-free gas into said container, charging a gel-forming solution into said container, and gelatinizing the solution. It can easily produce a large quantity of high quality polyacrylamide gel plates for electrophoresis with a homogeneous quality and a high resolving power in an automated batch method in a short period of time.

Abstract: A method of producing a decorative pattern on a plastic card housing an etronic circuit in an injection molding machine, includes the steps of introducing and positioning a film, which has applied on at least one surface thereof a decorative pattern, in an open cavity of the injection molding machine, closing the cavity so that the film is fixed and clamped in position, after the closing of the cavity, inserting an electronic circuit chip through an aperture into the mold cavity, injecting a support composition for the card into the mold cavity, and after termination of the injection process, removing the gate or any excess material from the periphery of the card, opening the mold cavity and removing the decorated card.

Abstract: A method and apparatus for producing light-weight construction panels having a cementitious core layer surfaced with a layer of reinforcing fabric bonded to the two faces of the core includes the use of slurry applicator having a supporting member and a doctor in addition to a moving carrier for the slurry coated fabric. The edges of the panel also are covered with the fabric and may be open mesh edges. Cementitious slurry, for example, portland cement slurry, is applied to the fabric by means of a supporting member over which the fabric is drawn and a doctor means adjustably mounted above the supporting member. The supporting member is of a non-base-reactive material such as polypropylene or stainless steel; the use of such a supporting member permits better application of the slurry to the fabric before placement of the slurry coated fabric on the moving carrier.

Abstract: In producing a blow-out port device in a two-stage inject:on molding process by use of synthetic resin, the blow-out port device having a housing including pairs of shaft bores and pairs of circular section bosses both provided in and on opposed wall portion of a peripheral wall of the housing, and a plurality of blades each including a pair of protruding portions provided at opposite ends of each of blade bodies disposed within the housing to abut against a pair of boss and to have the same outside diameter as the boss, and a pair of support shafts projectingly provided on end faces of the protruding portions and turnably fitted in the shaft bores, the housing is forced at a primary injection step, and then, the blades are formed at a secondary injection step by use of the shaft bores in the housing as support shaft-forming cavities. Thus, it is possible to provide an air-conditioning blow-out port device having an improved appearance around a mounting portion of each blade.

Abstract: Using a fiber reinforced thermoplastic resin, component materials of shapes obtained by partitioning the shape of the desired hollow article into a plurality of parts are molded. Reinforcing members 5, made of a prepreg wherein reinforcing fiber is impregnated with thermoplastic resin, are affixed to the junctions of these component materials 1. These are housed within mold 7 as a hollow provisional assembly and a joined unitary body is formed by adding pressure and heating. Using the method of the present invention, it is possible to efficiently manufacture a complicatedly shaped hollow article, the obtained molded article being one which excels in mechanical strength and, moreover, has a surface which is continuous and smooth.

Abstract: Gas turbine engines employ a variety of abradable liners to decrease the clearance between the rotating components and the surrounding casing. There is normally a trade-off between porosity, (and concomitant permeability) and the abradability of the liner material, such that materials with good abradability are permeable to gas flow--resulting in performance losses. Permeability of porous liners is decreased by infiltrating the liner with a low-viscosity liquid containing a metal or metal oxide. After infiltration, the viscosity of the liquid is substantially increased to prevent its egress from the porous liner. Thereafter, the liner is heated at an elevated temperature to drive off the remaining liquid and provide an oxide which blocks the passages and decreases the permeability of the liner.

Abstract: There is disclosed a process for preparing a resin composition for powder molding, comprising 50 to 97 wt % of a metal or alloy powder and 50 to 3 wt % of a thermoplastic resin having heat resistance and crystallinity, which process comprises dissolving the thermoplastic resin having heat resistance crystallinity in a solvent and at the same time, dispersing therein at least one metal or alloy powder selected from iron, brass, nickel silver, stainless steel and aluminum, having an average particle diameter of not more than 500 .mu.m to thereby prepare a mixture. In addition, there is disclosed a process for producing a powder molded product which comprises cold compressing molding the above resin composition and then heating the molding at a temperature not less than the melting point of the thermoplastic resin. This powder molded product has excellent dimensional stability against heat, chemical resistance, and mechanical strength.

Abstract: A ferrite steel suitable for use as the material of a part which is used at high and which is required to have high toughness at weld heat affected zones. The ferrite steel has a composition which contains C: not more than 0.02 wt %, Si: not more than 2.0 wt %, Mn: not more than 1.0 wt %, Cr: not less than 6.0 wt % but not more than 23.0 wt %, Ni: not more than 1.0 wt %, Nb: not less than 0.4 wt % but not more than 0.65 wt %, Co: not less than 0.01 wt % but not more than 2.0 wt %, Al: not more than 0.5 wt %, N: not more than 0.03 wt % and the balance substantially Fe and incidental inclusions.

Abstract: Disclosed are iron based, austenitic alloys of substantially reduced cobalt content compared to current cobalt based alloys, such as Stellite 1 and 6, which are substantially less expensive than current cobalt based alloys, which are machinable using standard machine processes and procedures, which can be deposited as a hard surface with a tight crack pattern or a smooth surface, which does not stress crack upon cooling, which provides substantially reduced radiation exposure by plant maintenance workers in nuclear power plants, and which has a superior hardness, lower friction coefficiency, metal to metal wear loss and erosion loss than cobalt based alloys, such as Stellite 1 and Stellite 6. The alloying content comprises from about 38.0 to 62.0 percent by weight, and has a cobalt content of from about 3.00 to 9.00 percent by weight.

Abstract: A Cr-Mo steel pipe having a wall thickness of 5 to 25 mm consisting essentially of 0.03 to 0.10 wt. % C, 0.5 to 1.0 wt. % Si, 0.3 to 0.6 wt. % Mn, 0.02 wt. % or less P, 0.007 wt. % or less S, 1.0 to 1.5 wt. % Cr, 0.45 to 0.65 wt. % Mo, 0.002 to 0.1 wt. % Al, 0.002 to 0.01 wt. % N, and the balance being Fe and unavoidable impurities. In the method of welding the Cr-Mo steel pipe, the Cr-Mo steel pipe is welded by shielded metal arc welding without a preheat treatment and/or a post weld heat treatment.

Abstract: Medical waste products including plastic and non-plastic elements are placed in a metal container which includes a raised insert element for supporting the waste above the bottom of the container. The container and used medical waste products are subjected to dry heat treatment at temperatures below the waste material flash points but of sufficient temperature and for a sufficient time to melt the plastic elements as well as to sterilize the contents. During the heating process the metal, rubber and other non-plastic elements remain on the raised insert; whereas, the molten plastic flows through or over the side of the insert to the bottom of the container. Upon cooling the plastic and non-plastic components of the medical waste products are separated as well as being sterile such that the container can be opened and the contents separately handled for appropriate recycling.

Abstract: Sodium perborate is mixed with a mixture, preferably a 1:1 mixture, of a rapid acetylating agent, e.g. TAED, and a slow acetylating agent, e.g. acetylsalicylic acid, in water to form a biocidally effective peracetic acid solution. When sodium perborate and TAED alone react in water, peracetic acid is produced quickly but has relatively little stability and a short useful life (curve 10). When sodium perborate and acetylsalicylic acid are mixed in water, the peracetic acid solution takes an extended duration to reach maximum efficacy, but is stable for an extended duration (curve 12). The mixture of rapid and slow acetylating agents quickly produces a stable peracetic acid concentration (curve 14).

Abstract: An automated chemical analyzer includes an automated conveyor apparatus for receiving a variety of sizes of test tubes, cuvettes, and sample tubes in a standard carrier member receivable into the analyzer. The standard carrier members may be interlocked in ranks and placed side by side in file to replicate the size and handling convenience of conventional test tube racks. However, the conveyor apparatus also provides for receipt of the carriers either as individuals for stat handling, or in interlocked ranks, or as rank and file groups for routine handling. The interlocked ranks of carriers are automatically unlocked from one another and fed along with the carriers having stat samples therein to a recirculating endless loop conveyor device which conveys the samples to at least one chemical analysis module, as well as providing a storage capacity both for samples in testing, and those samples awaiting verification of test results.

Abstract: A device for detecting contaminants in returned bottles, particularly in a high-speed bottle line, is disclosed. In the preferred embodiment, a sample chamber is rotated on a carousel unit between top and bottom bulkheads. The surfaces of the bulkheads facing the chamber are flat and substantially parallel, and the chamber has two open ends which face the two bulkheads, respectively. A blast of air is directed into the mouth of the bottle to be sampled, forcing the contents of the bottle through an aperture in the lower bulkhead and into the sample chamber. In the preferred embodiment, the analyzer contains a UV absorption analyzer and a photoionization detector. The carousel unit contains four sample chambers which rotate between a sampling station, the two detectors, and a purge station. The analyzer is controlled by a computer which issues a reject instruction to a bottle reject mechanism if the level of contaminants detected by either detector exceeds a predetermined threshold.

Abstract: The catalytic reactor has a catalyst member in the form of a stage of different orientations from one another and with flow-guiding elements which form crossing subflow ducts and which have a catalyst thereon. The flow-guiding elements are at an angle of inclination W of at least 10.degree. to the main flow direction and form partly open flow-crossing places between the subflows. The height H of a stage corresponds to a displacement factor H/HO of at least 1/2 where HO=Dctg W and D equals the diameter (or width) of the catalyst member. Satisfactory homogenization of the catalytic reaction and satisfactory heat removal via the heat-conductive rector wall are therefor achieved. The selectivity of the chemical reaction is improved and slip substantially obviated.

Abstract: The centrifugal fluidizing granulator for powder coating granulation has a sensor for detecting changes of viscosity of the growing particles by means of a load cell or a displacement detector; and output signal of the sensor is compared with the data stored in a memory contained in a control unit which determines whether the growing particles are in their wetted state or dried state. The control unit controls the spraying of the liquid and the dispersion of the guest powder based on the result of the comparison.

Abstract: An apparatus for sterilizing and breaking score lines on cartons prior to filling includes a spraying assembly for spraying sterilizing solution into the interior of the carton and a score line breaking assembly that breaks the score lines on the upstanding walls of the carton. The spraying assembly and the score line breaking assembly are located at the same station within a filling machine so that both operations can be performed simultaneously. The spray assembly includes a movably mounted spray head that is provided with a spray nozzle. The score line breaking assembly includes a breaker member that is operatively connected to a drive assembly for driving the breaker member into contacting relation with the upper portion of the upstanding walls of a carton in order to urge the upstanding walls of the carton inwardly and thereby break the score lines on the carton walls.

Abstract: A method of encapsulating radioactive materials inside fullerenes for stable long-term storage. Fullerenes provide a safe and efficient means of disposing of nuclear waste which is extremely stable with respect to the environment. After encapsulation, a radioactive ion is essentially chemically isolated from its external environment.

Abstract: This invention relates to a new form of crystalline material identified as having the structure of ZSM-18, to a new and useful method for synthesizing said crystalline material and to use of said crystalline material prepared in accordance herewith as a catalyst for organic compound, e.g., hydrocarbon compound, conversion.

Abstract: Improved emulsions of highly fluorinated organic compounds. The emulsions comprise a highly fluorinated organic compound, an oil, that is not substantially surface active and not significantly water soluble, and a surfactant. They are characterized by a well-defined relationship in the relative amounts of the three components.

Abstract: An entirely new class of reducing agents with substantially enhanced beneficial results is attained by employing polyoxyethyleneglycol dimercaptoalkylester compounds in a permanent waving lotion. This new class of reducing agents are water soluble, non-volatile and provide a substantially reduced malodor effect. Furthermore, by employing the dithiol compounds of the present invention as the reducing agent, long lasting hair conditioning and enhanced physical attributes, such as shine, luster, softness, manageability, and hair thickness, are also realized.

Abstract: An improved method and composition for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. The composition comprises a solution of a polymeric material having a molecular weight of about 500,000 or above having a concentration of from about 0.01 to about 15%, by weight.

Abstract: This invention provides a molecule comprising cyclosporine A or a congener of cyclosporine A which is photochemically attached to a ligand containing a reactive group. This invention also provides a composition of matter which comprises a conjugate of a compound and the aforementioned molecule wherein the compound is bound to the molecule through the reactive group. This invention further provides an antibody directed to the aforementioned composition of matter specific for cyclosporine A or congener of cyclosporine A. This invention also provides methods for detecting the presence of cyclosporine A or congener thereof, methods for detecting the concentration of cyclosporine A or congener thereof, as well as a method of monitoring levels of cyclosporine A or congener of cyclosporine A in a subject.

Abstract: A recombinant DNA molecule comprising a nucleotide sequence coding for a conformational epitope of the VP2 polypeptide of IBDV. In particular, a DNA molecule comprising a sequence which substantially corresponds to the AccI-SpeI fragment, and optionally the ScaI-XhoI fragment, of the IBDV genome segment coding for the VP2 polypeptide. Synthetic peptides or polypeptides, including fused polypeptides, prepared by expression of host cells containing these DNA molecules are also disclosed, as well as compositions for stimulating an immune response against IBDV comprising at least one such synthetic peptide or polypeptides.

Abstract: Disclosed are Bacillus thuringiensis isolates designated B.t. PS45B1, B.t. PS24J, B.t. PS94R3 B.t. PS17, B.t. PS62B1 and B.t. PS74G1 which produce novel .delta.-endotoxins active against acarid pests. Thus, these isolates, or mutants thereof, can be used to control such pests. Claimed are genes encoding these novel .delta.-endotoxins, which can be removed from these isolates and transferred to other host microbes, or plants. Expression of the toxins in microbe hosts results in the control of acarid pests, whereas transformed plants become resistant to acarid pests.

Abstract: The invention concerns novel isolates of Bacillus thuringiensis (B.t.) which contain a toxin(s) which is active against nematodes. This B.t. toxin(s) or B.t. isolate(s) can be used to treat animals and plants hosting susceptible nematodes.

Abstract: The method of preventing arterial thrombotic occlusion or thromboembolism by administering plasma-derived or recombinant produced protein C alone or in combination with a thrombolytic agent or combinations of thrombolytic agents.

Abstract: Fermentation product A87689 is produced by a strain of Amycolatopsis mediterranei selected from NRRL 18815 and NRRL 18851, or an A87689-producing mutant thereof. A87689, its C.sub.1-6 -alkyl ether and C.sub.1-6 -alkanoyl ester derivatives and pharmaceutically acceptable salts thereof are phospholipase A.sub.2 inhibitors that are useful as antiinflammatory agents. Fermentation products known as BU-3889V, its components and pharmaceutically acceptable salts thereof, are phospholipase A.sub.2 inhibitors that are also useful as antiinflammatory agents.

Abstract: A device useful for the treatment of infections of the middle ear in a prophylactic manner. A preferred device involves the use of a biodegradable support incorporating a therapeutically active agent, such as a drug. The device can be surgically inserted into the middle ear and there expand in order to substantially contact the walls of the middle ear. As it biodegrades, the expanded device provides prolonged, responsive release of active agent to the middle ear.

Abstract: A method for fabrication of multilayer transdermal drug release devices that divides the assembly of the various drug delivery components of the device into their unit operations; treats the prefabricated units as modules that are later combined to obtain the finished transdermal drug delivery device. A variety of different configurations are available depending upon the drug or drugs to be administered.

Abstract: There is disclosed a stable formulation of enalapril salt of the formula I ##STR1## which is prepared in such manner that a compound of formula II ##STR2## is suspended in demineralized water and a stoichiometric amount of the corresponding sodium compound such as sodium carbonate, sodium hydrogen carbonate or sodium hydroxide is added thereto, to this enalapril sodium salt prepared in situ of the formula I ##STR3## formulating additives are added, the whole is homogenized and formulated.