Abstract: An aqueous external dispersion comprising a wax dispersant and an organic crystal modifier composition dispersed through a continuous water phase is useful as a crystal modifier for petroleum or a petroleum-derived liquid. The dispersant comprises a non-ionic surfactant and is present in the dispersion in an amount sufficient to impart at least meta-stability to the dispersion. The dispersion has a viscosity at 25.degree. C. of less than about 50,000 centipoise.

Abstract: The invention relates to a gel made of apolar medium including:an apolar medium,a "multichain" liquid surface-active agent in acidic form, soluble or dispersible in the said apolar medium,an agent for neutralizing the said "multichain" surface-active agent,from 0.2 to 5 molecules of water per molecule of "multichain" surface-active agent,optionally at least one emulsifying agent and/or a solid filler which is soluble or insoluble in the apolar medium.This gel may be employed for the formulation of water-based drilling fluids.

Abstract: A composition for use in lubricants and function fluids to provide improved anti-shudder and shudder durability properties to an automatic transmission. The composition comprises alkoxylated fatty amines as well as a mixture of other friction modifiers.

Abstract: 1,8-Naphthalimide derivatives of Formula (I) are useful as fluorescent dyes: ##STR1## wherein R.sup.1 and R.sup.2 are each independently selected from the group consisting of branched alkyl groups containing 7-8 carbon atoms and alkyloxyalkyl groups containing 4 to 24 carbon atoms.

Abstract: A lubricating composition of the present invention comprises a base oil for lubricating oil or base grease; at least one molybdenum compound as component (A) selected from the group consisting of a selected sulfurized oxymolybdenum dithiocarbamate, a selected sulfurized oxymolybdenum dithiophosphate and a selected molybdenum amine compound; and a (poly)glycerol ether and/or a (poly)oxyalkylene glycol monoalkyl ether as component (B).

Abstract: Lubricating oil composition for internal combustion engines includes a base oil containing (A) 30-98% by weight of a mineral oil having a kinematic viscosity of 2-30 mm.sup.2 /sec at 100.degree. C. and a viscosity index of not less than 100 and (B) 2-70% by weight of poly-.alpha.-olefin, and zinc dithiophosphate in an amount corresponding, as reduced to the amount of P (phosphorus), to 0.02-0.15 parts by weight with respect to 100 parts by weight of the base oil. The composition of the present invention is advantageously used as lubricating oil composition for internal combustion engines, exerting excellent effects in terms of the consumption of the oil composition, fuel consumption rate, and sealing characteristics of rubber.

Abstract: An improved lubricant for coating moving webs is provided. The lubricant includes a chemically modified lecithin, such as hydroxylated or acethylated lecithin, and a fatty ester to completely eliminate the need for a surfactant in the composition. The mixture avoids foaming while maintaining the coating structure, even at high speeds found in modern printing equipment and processes. The lubricant improves coating rheology and maintains coating structure. The lubricant maintains a homogeneous coating, even at high speeds, thus resulting in superior coating and paper characteristics.

Abstract: An enhanced biodegradable grease composition that is environmentally friendly, as well as several processes for preparing the grease composition is described which comprises(A) a base oil wherein the base oil is a natural oil or synthetic triglyceride of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are aliphatic groups that contain from about 7 to about 23 carbon atoms;(B) at least one performance additive comprising(1) an alkyl phenol,(2) a benzotriazole, or(3) an aromatic amine; and(C) a thickener wherein the thickener (C) is a reaction product of (C1) a metal based material and (C2) a carboxylic acid or its ester.The enhanced biodegradable lubricating grease may also contain (D) a viscosity modifier, (E) a pour point depressant, or mixtures of (D) and (E).

Abstract: Power transmitting fluids, especially automatic transmission fluids, possess improved properties such as antiwear, durability, antioxidation, and shift-time performance by incorporation of high viscosity polyalphaolefins.

Abstract: Described is a detergent composition comprising (A) a sulfate ester surfactant, (B) at least one surfactant selected from amphoteric surfactants, amine oxide surfactants, alkanol amide surfactants and amide amino-acid surfactants, (C) a cationic bactericide and (D) a metal chelating agent, the weight ratio of said (A) to (B) being 1-50 and the content of said (C) being 0.2 wt. % to 5 wt. %.The detergent composition according to the present invention has excellent detergency, foamability and foam durability and at the same time, has high bactericidal effects because it can be mixed stably with a cationic bactericide.

Abstract: The present invention provides non-oxidative methods for treating contact lenses and compositions for the same. The present invention includes contacting a lens with an aqueous solution comprising a phosphonic acid compound. In preferred embodiments of the invention, the subject phosphonic compounds are used in combination with antimicrobial agents for providing simultaneous disinfection and cleaning of contact lenses including the prevention or removal of protein deposits.

Abstract: Liquid personal cleansing compositions which comprise a complex coacervate, a lipophilic skin moisturizing agent, a stabilizer, a lathering surfactant and water are disclosed. The complex coacervate comprises particles having a particle size distribution such that at least about 10% by weight of the particles have a diameter of at least about 20 microns. The particles comprising the complex coacervate comprise 1) a polycation having a minimum filtrate with of about 10 grams, and 2) a polyanion. The complex coacervate is essentially free of cross-linking agent.

Abstract: A method of enhancing deposition of benefit agent from bars which method comprises separately preparing an adjuvant composition comprising benefit agent and deposition polymer (e.g., cationic polymer); and base bar composition comprising a surfactant system, wherein the adjuvant composition is initially prepared by mixing components forming the adjuvant composition and water to form a uniform aqueous mixture containing benefit agents having particle size of 0.1 .mu.m to 100 .mu.m and drying said aqueous mixture to form a dried adjuvant composition. By combining adjuvant compositions separately from the base bar composition, it is possible to create a final bar having enhanced deposition of benefit agent without compromising processing or consumer attributes (e.g., foaming).

Abstract: A hardened image is removed from printing plates by a solution of formic acid and hydrofluoric acid. In one embodiment, the solution further includes a buffer solution to maintain the oleophilic properties of the substrate for printing.

Abstract: The invention is a method of removing soils containing oils and fats from food processing surfaces. The method includes the steps of formulating a wash composition from a two-part concentrate. The concentrate first part includes a source of alkalinity and water. The concentrate second part includes a quaternary ammonium compound. After formulation, the wash composition has a major portion of water, from about 100 ppm to 20,000 ppm of quaternary ammonium compound, and an alkali source present in a concentration to provide a pH of from about 10 to 14. After formulation, the wash composition may be used by applying it to the food processing surface. Optionally, the wash composition may also include a chelating agent and a second nonionic or anionic detersive agent.

Abstract: An engine cleaner composition and method for removing carbonaceous deposits from engine fuel-system components such as mechanical and electronic fuel injectors, intake valve seats, valves, combustion cylinders, spark plugs, and oxygen sensors may be used on both gasoline and diesel engines. Preferred compositions comprise a synergistic solution of a heterocyclic ring compound in an azeotrope of acetonitrile and water, together with selected surfactants and aromatics. Preferred compositions of the invention may be placed in an aerosol pressurized unit utilizing a compressed gas, such as nitrogen or nitrous oxide, or compressed liquid gas, such as a hydrocarbon or fluorohydrocarbon. Preferred engine cleaning compositions of the invention are substantially non-ozone depleting, are low in global warming, and have a low order of human toxicity. Preferred compositions have a moderate pH and are essentially compatible with metals and elastomers conventionally used in engine fuel-system components.

Abstract: Reworkable encapsulant formulations are being developed to allow recovery of part-good microelectronic assemblies. According to this invention, a gelled form of the solvent is useful for removing the reworkable encapsulant from a specific region of the assemblies without affecting components on the assembly which do not need to be reworked. This novel method eliminates expensive tooling that would otherwise be required to handle the solvent.

Abstract: Polycarboxylate additives suitable for use in automatic dishwasher detergent compositions are prepared by polymerizing three or more monomers including monoethylenically unsaturated C.sub.3 to C.sub.6 monocarboxylic acids such as acrylic acid, monoethylenically unsaturated C.sub.4 to C.sub.6 dicarboxylic acids such as maleic acid, and monoethylenically unsaturated esters of acrylic or methacrylic acid. Automatic dishwasher detergents prepared from these additives produce low filming and spotting on washed glassware.

Abstract: The invention pertains to granules which incorporate citric acid monohydrate as an exotherm control agent within a peracid containing core. The granules have improved dissolution rates of the peracid in a dishwashing cycle. Compositions containing the granules are also described.

Abstract: There is provided a detergent composition comprising conventional detergent components characterized in that it contains a lactase enzyme. The lactase enzyme is preferably incorporated into the compositions at a level of from 0,0001% to 2% active enzyme by weight of the composition.

Abstract: A metal cleaning composition comprising EDDS is described. Preferably, the compositions comprise optical isomers of EDDS, such as (s,s)EDDS. The compositions are particularly well suited for cleaning iron, zinc, aluminum, and copper. De-icer compositions comprising EDDS are also described. Also disclosed are processes for using the compositions.

Abstract: Liquid laundry detergent compositions comprising water soluble and/or dispersible, modified polyamines having functionalized backbone moieties which provide cotton soil release benefits (optionally in combination with non-cotton soil release agents) and protease enzymes.

Abstract: Novel bleaches, a method for bleaching substrates using these materials and bleaching compositions containing same are reported. The bleaches are N-acylimines. Substrates such as fabrics may be bleached in an aqueous solution containing the N-acylimines and a peroxygen compound.

Abstract: Liquid detergent compositions containing a branched anionic surfactant. These compositions are low sudsing and have improved hydrophobic greasy soil removal performance.

Abstract: This invention provides a liquid laundry detergent product with freeze/thaw and high/low temperature stability. The detergent product is an aqueous medium having a content of sodium carbonate detergent builder, and a surfactant blend of specific amounts of two anionic salt compounds and two nonionic compounds of specific chemical structure.

Abstract: The present invention provides an enzyme-containing granulated product containing, in a uniformly dispersed state, an enzyme and one or more stabilizers selected from the group consisting of reducing agents and antioxidants. The invention also discloses a method for the production of the granulated product, as well as bleaching agents and detergent compositions containing the granulated product. The granulated product loses only a minimal level of enzyme activity even in the copresence of a bleaching agent, and exhibits excellent solubility. Therefore, bleach compositions and detergent compositions prepared by incorporating the granulated product fully exhibit the enzyme activity and bleaching activity.

Abstract: A 1-bromopropane composition is disclosed, which stays stable even under the condition that it is repeatedly used at high temperatures over an extended period of time as in vapor degreasing. The stabilized 1-bromopropane composition comprises 100 parts by weight of 1-bromopropane, from 0.1 to 5 parts by weight of nitromethane, and from 0.1 to 5 parts by weight of 1,2-butylene oxide or trimethoxymethane.

Abstract: The invention relates to cleaning compositions in the form of microemulsions for cleansing the skin or for the manual cleaning of hard surfaces. These cleaning compositions consist of oil, water, surfactant and cosolvent. As surfactant, use is made of a surfactant system consisting of 80-100% alkylpolyglycoside and 0-20% auxiliary surfactant, of anionic, nonionic or betaine type, whose choice is largely arbitrary. The cosolvent is an oligoester of polybasic carboxylic or hydroxycarboxylic acids with C.sub.1 to C.sub.4 alcohols. The microemulsions are highly stable and can be diluted in water without problems.

Abstract: This invention relates to a method of manufacturing a concentrated aqueous solution of an amine oxide and the use of the solution in cleaning compositions.

Abstract: An improvement is described in all purpose liquid cleaning microemulsion composition which is especially effective in the removal of oily and greasy soil and also exhibiting improved foam collapse properties, contains an anionic detergent, an ethoxylated nonionic surfactant, an ethoxylated/butoxylated nonionic surfactant, optionally, a partially esterfied ethoxylated polyhydric type alcohol, a hydrocarbon ingredient, and water.

Abstract: A process for the manufacture of detergent compositions from a surfactant paste which is substantially in the solid phase at temperatures of 25.degree. C. and below comprises the steps of: (i) mixing the surfactant paste at a temperature above its softening point, the surfactant paste comprising at least 50% by weight of nonionic surfactant; (ii) forming the molten surfactant paste into drops on a cooling surface; (iii) forming solid pastilles by cooling the drops of molten surfactant paste; and (iv) removing solidified pastilles from the cooling surface.

Abstract: The use of 4-tert-butyl-1-cyclohexanol as an antioxidant in soaps, shampoos and other cosmetic products, as well as in all-purpose cleaners, is described.

Abstract: Glassy particles containing agents useful for laundry and cleaning products (preferably perfumes, bleaching agents, soil release polymers), and laundry and cleaning products containing these glassy particles. The particles comprise a glass derived from one or more at least partially water-soluble hydroxylic compounds, such as hydrogenated starch hydrolysates, sucrose, glucose, and starch hydrolysates. The glassy particle also has a hygroscopicity value of less than about 80%.

Abstract: A fabric softening composition comprising a compound of formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are independently selected from C.sub.1 -C.sub.4 alkyl groups or C.sub.2 -C.sub.4 alkenyl groups, a is from 1 to 4, x.sup.- is a compatible anion and R.sup.4 and R.sup.5 are independently selected from C.sub.12 -C.sub.22 alkyl or alkenyl groups, the sum of the chain lengths or R.sup.4 and R.sup.5 preferably being at least 30.

Abstract: The invention relates to a process for the production of light-colored surfactants in which the surfactants are stabilized before bleaching by addition of antioxidants.

Abstract: Lysostaphin is used to eliminate and cure staphylococcal infections including the cure of mastitis by intramammary infusion. Administration of from 2 mg to 400 mg of lysostaphin to an infected bovine mammary gland eliminates staphylococci, and the reoccurrence common with antibiotic therapy is not observed. Teat-dips containing lysostaphin, mutanolysin and lysozyme can be used as a prophylactic. Synergistic enhancement of the killing effect of lysostaphin is observed when a mild surfactant or penicillin or both is included in the formulation.

Abstract: A method of enhancing tolerance of a porcine transplant in a xenogeneic recipient by administering porcine bone marrow cells to the recipient and of enhancing proliferation and engraftment of the porcine bone marrow cells by exposing said cells to at least one substantially pure porcine cytokine and porcine cytokines that are substantially free of other porcine proteins and preferentially enhance the proliferation and engraftment of porcine bone marrow cells in the presence of bone marrow cells of other species. Protein and DNA sequence(s) for such porcine cytokines.

Abstract: Pharmaceutical compositions comprising as active ingredient a synthetic random copolymer of average molecular weight of about 4,000-12,000, preferably 6,000-8,000, said copolymer consisting of glutamic acid (Glu), lysine (Lys), alanine (Ala) and tyrosine (Tyr) residues in a relative molar ratio of 1.4-2.1 parts of Glu to 3.2-4.4 parts of Lys to 4.0-6.0 parts of Ala to 1.0 parts of Tyr (herein GLAT copolymers), can be used in a method for prevention and treatment of graft-versus-host disease in patients in the course of bone marrow and organ transplantation.

Abstract: The invention provides the use of a protein selected from the B-oligomer of pertussis toxin, an individual subunit S2, S3, S4 or S5 thereof, or a combination of the subunits, for the preparation of pharmaceutical compositions comprising them for the treatment of autoimmune diseases.

Abstract: A method of enhancing fetal growth and/or development and/or neonatal survival by the administration over a period of insulin-like growth factor (IGF-1), to either the amniotic fluid or direct to the fetal gastrointestinal tract. Administration may be by way of an ultrasonically monitored injection or placement of a catheter.

Abstract: Methods for identifying factors that regulate appetite are disclosed. Preferably, the methods feature determinination of decreased food consumption in selected recipient mammals following administration of a test sample. A product having appetite suppressing activity is also described. In addition, methods for reducing food consumption in a mammal, featuring administration of a pharmaceutical composition comprising a representative appetite suppression factor, are disclosed.

Abstract: Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharmaceutical formulation or dosage forms for use in the methods.

Abstract: Provided are therapeutic methods employing preparations of recombinant soluble Complement Receptor type 1 (sCR1) defined with respect to the distribution of sCR1 glycoforms. The methods are suitable for treatment of disease involving inflammation, inappropriate complement activation, and in thrombotic or shock state conditions. Preferred methods employ sCR1 glycoforms that are sialylated, have a pI of .ltoreq.5.1, or have a sialic acid:mannose molar ratio of .gtoreq.0.25.

Abstract: A novel polypeptide derived from the leech Hirudo medicinalis was found to be able to inhibit Factor Xa thereby reducing the extent of blood coagulation. The polypeptide is useful in treating conditions of excessive blood coagulation. A recombinant organism containing cDNA encoding the polypeptide has been deposited in the ATCC under Accession No. 69134. Recombinant microorganisms able to produce the polypeptide have been deposited in the ATCC under Accession Nos. 69135, 69137 and 69269.

Abstract: The present invention relates to a peptide represented by formula ?I!. The peptide of the present invention exhibits allergic and anallergic inflammation inhibitory, antibacterial, antitumor and wound-healing effects, and it is useful as an inflammation inhibitor, immunosuppressive agent, antibacterial agent, antitumor agent, wound-healing agent, antiulcer agent, and so forth. Accordingly, the present invention also provides therapeutic agents having the above-mentioned pharmacological effects.

Abstract: The present invention provides antithrombotic agents useful for the management of cardiovascular disease. The agents of the subject invention are novel cyclic peptides encompassed by the following formula:Y-X.sub.1 -X.sub.2 -G-D-X.sub.3 -X.sub.4 -X.sub.5 -Z(SEQ ID NO. 1). In the above formula, X.sub.2 and X.sub.3 are independently a hydrophobic amino acid and X.sub.4 is a positively charged amino acid. The X.sub.1 and X.sub.5 substituents are independently zero to five amino acids. The amino and carboxy terminal amino acids of a given peptide can be modified according to the substituents Y and Z, respectively. The peptides are cyclized through a bridge between the two amino acids with the peptide, excluding G, D and X.sub.3 in the formation of the bridge. Peptides encompassed by the above formula can be administered in a suitable physiologically acceptable carrier to therapeutically treat thrombosis and conditions resulting from the development of thrombi.

Abstract: The invention features a novel recombinant polypeptide that transactivates the somatostatin promoter, the polypeptide being present in pancreatic duct cells and not present in pancreatic .alpha.-cells, the polypeptide being encoded by a gene which encodes a protein on the order of 31 kd.

Abstract: The present invention relates generally to anti-fungal peptides derived from or based on Domain III (amino aids 142-169) of bactericidal/permeability-increasing protein (BPI) and in vivo or in vitro uses of such peptides.

Abstract: An oxyntomodulin peptide has cardiotonic activity and insulin release-promoting activity. The peptide or pharmaceutical salts thereof can be used for prevention or treatment of cardiopathy or diabetes.

Abstract: A human gene has been discovered which is genetically altered in human tumor cells. The genetic alteration is gene amplification and leads to a corresponding increase in gene products. Detecting that the gene, designated hMDM2, has become amplified or detecting increased expression of gene products is diagnostic of tumorigenesis. Human MDM2 protein binds to human p53 and allows the cell to escape from p53-regulated growth.