Patents Issued in March 6, 2001
  • Patent number: 6197248
    Abstract: A process for preparing a powder of aluminum titanate, including the steps of subjecting to pressure molding a mixture of 100 parts by weight of a mixture of Al2O3 and TiO2 at a molar ratio of the former: the latter of 1:0.95-1.05, 2 to 5 parts by weight of SiO2, 2 to 5 parts by weight of iron oxide calculated as Fe2O3 and 1 to 3 parts by weight of a powder of an organic substance; sintering the molded product at a temperature of 1600 to 1700° C. in a closed container; and pulverizing the molded product. A further process for preparing a sintered body of aluminum titanate includes the steps of molding the powder of aluminum titanate obtained by the above-mentioned process and sintering the molded product at 1450 to 1550° C.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: March 6, 2001
    Inventors: Tsutomu Fukuda, Masahiro Fukuda
  • Patent number: 6197249
    Abstract: The invention relates to an apparatus for conducting gas through material (1) to be sintered, which material is set in an essentially continuous motion, particularly when gas is used for sintering the material; said apparatus comprises a flow guide (7) for conducting gas essentially near to the material (1) to be sintered, and a gas collecting member (10) for collecting the gas that has been made to penetrate the material to be sintered. According to the invention, in the gas flow guide (7) the gas inlet (8) is located centrally with respect to the material (1) to be sintered, and the gas outlet (9) extends essentially over the whole material to be sintered in the transversal direction, when observed in the proceeding direction of said material; and the gas collecting member (10) is composed of funnel elements (11), which are installed essentially at the gas flow apertures (5) provided in the member for conveying the material to be sintered.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: March 6, 2001
    Assignee: Outokumpu Technology Oy
    Inventors: Eero V{umlaut over (aa)}nänen, Lauri Mustikka
  • Patent number: 6197250
    Abstract: A dross pot and sow mould combination for use with a dross press, the combination being suitable for melting furnaces with low sills. The sow mould is connected to the dross pot by a variable length connection which allows the height of the combination to be low when the combination is positioned by the furnace, but larger when the combination is positioned in the dross press.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: March 6, 2001
    Assignee: J. McIntyre (Machinery) Limited
    Inventor: Alan Bramley
  • Patent number: 6197251
    Abstract: A porous metal material (22) is manufactured by a method comprising a step of utilizing a magnetic field to orient numerous metal staple fibers (3), and holding these metal staple fibers (3) on the metal substrate sheet (9) in a state of being more or less perpendicular thereto by means of an adhesive (19) supplied to the metal substrate sheet (9), and a step of removing the adhesive (19) by pyrolysis, and integrally joining the metal staple fibers (3) and metal substrate sheet (9) by sintering.
    Type: Grant
    Filed: February 26, 1998
    Date of Patent: March 6, 2001
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Akira Hashimoto, Junjirou Awano, Katsuhiro Okamoto, Tsumoru Ohata, Yoriko Takai, Masaki Hirokoh
  • Patent number: 6197252
    Abstract: The invention relates to a method of removing water-insoluble binder from a porous article formed from pressed particulate material, such as tantalum powder. The invention provides a method capable of removing substantially all of the binder from the article for high purity applications, such as capacitor manufacture. The method comprises contacting the article with an aqueous solution of an agent which reacts with said binder to produce a water soluble derivative thereof whereby said binder derivative may be substantially dissolved in said solution. In a particular embodiment, the derivative is produced by hydrolysis of a fatty acid binder.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: March 6, 2001
    Assignee: AVX Limited
    Inventors: Ian H. Bishop, David Masheder
  • Patent number: 6197253
    Abstract: An alloy comprising tin, antimony, bismuth and indium and a method for making the same is disclosed. The alloy is used in the hardware, jewelry, statuary, filigree, or other ornament casting art. A preferred embodiment of the alloy comprises 97% by weight tin, 1% by weight antimony, 1% by weight bismuth, and 1% by weight indium.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: March 6, 2001
    Inventors: Allen Broomfield, Everett George Morrissey
  • Patent number: 6197254
    Abstract: A self-contained and highly portable assaying system includes a luminometer and a detector cap assembly. The detector cap assembly, which is structured with a first portion and a second portion, is capable of collecting a specimen, and causing a bioluminescent or chemiluminescent assaying reaction to be conducted in a light-tight environment within the detector cap assembly (devoid of any available ambient light). The luminometer is structured to be removably fixed to the detector cap assembly to sense low level luminescent emissions produced by the assaying reaction. A quantified result is subsequently provided to a user or operator that indicates the outcome of the assay activities.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: March 6, 2001
    Assignee: International Food Protection
    Inventors: Lawrence Stanley Silver, Michael Juliano, Adelbert M. Gillen
  • Patent number: 6197255
    Abstract: A chemical analyzing apparatus comprises a reaction cell holder which holds a plurality of reaction cells that are supplied with samples and reagents at a predetermined position, a measurer for measuring characteristics of the sample, a plurality of reagent containers, a liquid deliverer provided below each of the plurality of reagent containers, one or more sound wave generators provided outside the reaction cells, and storage containers for storing cleansing liquid with different contamination states. The cleansing liquid with different contamination states is reused according to the contamination levels of the reaction cells.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: March 6, 2001
    Assignee: Hitachi, Ltd.
    Inventors: Ryo Miyake, Yoshihiro Nagaoka, Akira Koide, Naruo Watanabe, Yasuhiko Sasaki, Hajime Kato, Takao Terayama, Hiroshi Mitsumaki, Hiroyasu Uchida, Takeshi Shibuya, Yasuhiro Yoshimura
  • Patent number: 6197256
    Abstract: An analyzing system for analyzing fluid samples includes a measuring buoy immersible in a body of fluid to be tested. The buoy forms a sample chamber in which samples of the fluid are to be tested. The sample chamber communicates with a settling chamber through a chamber opening, and the settling chamber communicates with the body of fluid through a floor opening formed in the buoy below the chamber opening. A gas exchange apparatus communicates with the sample chamber and with a source of air or gas for introducing the air or gas into the sample chamber to drain sample fluid therefrom, and for discharging the air or gas from the sample chamber to admit sample fluid into the sample chamber from the settling chamber. A testing device is disposed in the sample chamber for testing the sample fluid, and is connected to a control and analysis device.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: March 6, 2001
    Assignee: ISCO Inc.
    Inventor: Friedrich Wilhelm Siepmann
  • Patent number: 6197257
    Abstract: A micro sensor device for measuring a concentration of a substance within a sample comprises an integrated sensor head having a tip portion adapted to be inserted into a sample, a light source for emitting a beam of light into and through the tip portion with the tip portion capable of interacting with a substance within a sample to produce a reflected pattern of light, and a detector for receiving the reflected pattern of light, and a body portion coupled to the integrated sensor head, the body portion comprising a processor operatively connected to the light source and the detector, the processor for controlling the light source for emitting the beam of light, for receiving the pattern of reflected light from the detector, and for processing the reflected pattern of light to determine the concentration of a substance within a sample.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: March 6, 2001
    Assignee: Microsense of St. Louis, LLC
    Inventor: Eric J. Raskas
  • Patent number: 6197258
    Abstract: The invention described in detail herein relates to the detection, determination, and quantitation of certain ions and small molecules in solution. The invention specifically relates to improvements in the area of photoluminescent sensors for use in a detection scheme involving the alteration of a photoluminescent label or moiety attached to or associated with an analyte binding macromolecule. One may use the changes in photoluminescence lifetime, changes in ratios of photoluminescence intensity or changes in photoluminescence polarization (anisotropy) to determine the analyte. The photoluminescence change measured correlates to the concentration of the ion or molecule in solution.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: March 6, 2001
    Assignee: University of Maryland, Baltimore
    Inventors: Richard B. Thompson, Vincent L. Feliccia, Badri P. Maliwal, Carol A. Fierke
  • Patent number: 6197259
    Abstract: A plastic pipette tip easily and firmly mountable on and easily ejectable from a pipette mounting shaft of a pipette by application of relatively small axial mounting and ejection forces of about six and three (3) pounds respectively. The pipette tip includes a tubular proximal portion comprising (i) a frusto-conical open upper end portion having an inner diameter at its upper end greater than the diameter of a mounting shaft of the pipette to which the pipette tip is to be mounted, (ii) a hollow mid-portion and (iii) an annular sealing region at a junction of the open end and mid-portions. The annular sealing region has an inner diameter less than “x” and is designed to engage a lower end of a sealing zone of the mounting shaft to stretch radially outward as the mounting shaft is guided and stably oriented in the proximal portion thereby creating a fluid tight seal between the sealing zone and the sealing region.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: March 6, 2001
    Assignee: Rainin Instrument Co., Inc.
    Inventors: Christopher Kelly, James S. Petrek
  • Patent number: 6197260
    Abstract: The reagent package includes a container housing section and a container lid that are sealed together to define one or more inside chambers. An opening in the container lid provides access to a corresponding chamber. The chamber opening is controlled by a valve that is pivotable from an open position to a closed position and vice versa. When the valve is in an open position the container chamber can be accessed through the valve with an aspiration probe and a dispensation probe. The reagent package accommodates a filter screen member and a glass ampoule in the container chamber. The glass ampoule contains one reagent ingredient, which can be a dry powder and the space within the chamber outside the glass ampoule can contain a reconstituting liquid. When the reagent package is ready for use a pressure force is imposed on the outside wall of the chamber adjacent the glass ampoule to crush the ampoule and permit the liquid within the chamber to mix with the dry powder released from the glass ampoule.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: March 6, 2001
    Assignee: Bayer Corporation
    Inventors: Randolph Bradshaw, Andrew Oakes, Nicholae Dumitrescu, Robert L. Berger, William M. Jameson, Chris Robinson, James R. Laskey
  • Patent number: 6197261
    Abstract: A machine for opening simultaneously a plurality of blood segments comprising a number of segment carriers laterally co-joined and having therein strictly located apertures, an attached needle guide having perforations aligned with the carrier apertures and a spring-returned handle assembly containing captive needles to the same number as, and aligned with, the carrier apertures and guide perforations. Activation of the handle forces the needles to penetrate all blood segments in the carriers. A base tray is provided to contain any possible leakage from the segments.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: March 6, 2001
    Inventors: Richard A. Linville, Renée A. Linville
  • Patent number: 6197262
    Abstract: A device (1) for the depuration and sanitization of air comprising a tank (10) divided into at least two compartments (17-18) containing suitable liquids into which penetrate the lower parts of relative groups of perforated discs (21) arranged, suitably spaced one from the next, on a shaft (20), placed horizontally and set at its ends onto supports (131-141) obtained centrally on the transverse walls (13-14) which are at the extremities of the tank (10) and connected at one end to a geared electric motor (40). The upper parts of the perforated discs (21) are housed in a semicylindrical casing (30) in which they are traversed by the air drawn in by means of a fan (7). The liquids inserted into the compartments (17-18—etc.) of the tank (10) consist of a basic aqueous solution, with the addition of a surfactant and eventually antifoaming agents, to which can be added quaternary ammonium salts and/or organic salts whose adsorbing action allows also the sanitization of the treated air.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: March 6, 2001
    Inventor: Sante Del Ben
  • Patent number: 6197263
    Abstract: The invention is an air freshener for use in automobiles, having a base-power unit and a detachable fragrance dispersing unit. The fragrance dispersing unit has a heating element disposed therein and is adapted to receive standard replaceable gel-scent cartridges. The detachable fragrance dispersing unit can be attached to an automobile vent system to utilize the vehicle's air moving system to disperse the fragrance throughout the automobile. The power supply in the base-power unit allows a user to select between drawing power from a cigarette lighter plug, a battery disposed within the base power unit, or a solar electric cell disposed on the outer surface of the base power unit.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: March 6, 2001
    Inventor: Eugene D. Blount
  • Patent number: 6197264
    Abstract: A process for polymerization of olefin monomers by forming a fluid stream containing catalyst, continuously feeding the fluid stream into an elongated polymerization reactor having at least two successive chambers separated by dividing plates having a diameter slightly smaller than that of the polymerization rector, feeding monomers, and an optional catalyst and donor into the polymerization reactor under temperature conditions to polymerize the olefin while maintaining a mixed flow in the chambers to polymerize the monomers and optional comonomer in the fluid, and removing the resultant polymer slurry from the polymerization reactor.
    Type: Grant
    Filed: October 19, 1998
    Date of Patent: March 6, 2001
    Assignee: Borealis A/S
    Inventors: Esa Korhonen, Pauli Leskinen, Ward Mennes, Fred Bergmann
  • Patent number: 6197265
    Abstract: The present invention provides an improved method for constructing a gas distribution system which creates two distinct reaction zones within the same fluidized bed. The invention provides for the distribution of one type of gas at the bottom of the fluidized bed and a second type of gas at a higher level in the fluidized bed. The system is constructed of a plurality of modular units constructed entirely of refractory materials. The modules are fitted and linked together to form a grid, the size of which can be varied to accommodate different reactor sizes.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: March 6, 2001
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Thomas D. Wheelock
  • Patent number: 6197266
    Abstract: A cyclone leg sealing system is composed of one or more intermediate solids-accumulation chambers delimited by two sealing valves and in series, the function of the valves being to prevent the back-flow of particulate material towards the inside of the separating cyclones in fluid catalytic cracking (FCC) processes, thereby ensuring the maximum efficiency of the separating effected by the cyclone.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: March 6, 2001
    Assignee: Petroleo Brasileiro S. A.-Petrobras
    Inventors: Jose Mozart Fusco, Eduardo Cardoso De Melo Guerra, Valmor Neves Vieira
  • Patent number: 6197267
    Abstract: A reactor for corona destruction of volatile organic compounds (VOCs), a multi-surface catalyst for the reactor and a method of making the catalyst for the reactor. The reactor has a catalyst of a high dielectric material with an enhanced surface area. A catalyst layer stack is formed by depositing a high dielectric layer on a substrate and, then depositing a conductive layer on the dielectric layer. The catalyst layer stack is bombarded by low RF energy ions to form an enhanced surface area and to form a protective layer over the conductive layer. Catalyst layer stacks may be joined back to form double-sided catalyst layer stacks. The catalyst layer stack may be diced into small pieces that are used in the reactor or the whole catalyst layer stack may be used.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: March 6, 2001
    Assignee: International Business Machines Corporation
    Inventor: Munir-ud-Din Naeem
  • Patent number: 6197268
    Abstract: Nitrogen oxides are removed from a waste gas stream by contacting the waste gas stream with ammonia, thereby reducing the nitrogen oxides to nitrogen. Residual nitrogen oxides and unreacted ammonia in the waste gas stream leaving the nitrogen oxides reducing step are oxidized to nitrogen pentoxide or nitric acid by contacting this gas stream with ozone. Contact of the ozone and waste gas is preferably carried out in the presence of an aqueous solution at a pH above about 9 and at a temperature above about 75° C., and this step is preferably carried out in the presence of an ammonia-oxidizing catalyst.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: March 6, 2001
    Assignee: The BOC Group, Inc.
    Inventors: Shuen-Cheng Hwang, Neeraj Saxena, Mark H. Anderson, Robert James Ferrell
  • Patent number: 6197269
    Abstract: Membrane gas adsorption is conducted wherein the gas phase contains mercury in the gaseous state and the liquid phase containing at least one oxidizing agent for mercury such that the mercury in the gaseous state is absorbed into the liquid phase, and an oxidation/reduction reaction between the mercury and the oxidizing agent takes place in one step.
    Type: Grant
    Filed: March 6, 1998
    Date of Patent: March 6, 2001
    Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek (TNO)
    Inventors: Albert Edward Jansen, Paul Hubert Maria Feron
  • Patent number: 6197270
    Abstract: There is provided a process for producing an aerogel which comprises lowering a pH of a water glass solution to obtain a sol, gelling the sol to obtain a hydrogel, replacing water in the gel with an organic solvent, reacting the gel with a hydrophobilizing agent having hydrophobic groups as well as functional groups reactive with silanol groups in liquid phase, followed by supercritically drying; or hydrophobilizing and supercritically drying the resultant gel at the same time. Preferably, the hydrogel is prepared by ion exchanging alkali metals in the water glass solution using an ion exchange resin to obtain a sol which is subjected to suspension polymerization.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: March 6, 2001
    Assignee: Matsushita Electric Works, Ltd.
    Inventors: Kenji Sonoda, Hiroshi Yokogawa, Masaru Yokoyama, Kenji Tsubaki
  • Patent number: 6197271
    Abstract: Disclosed is a reactor and process for exothermic vapour phase reaction, wherein the reactor (1; 101) comprises a pressure vessel (2; 102) having an inlet (3;103) for reactant(s) and an outlet (4; 104) for products; a plurality of beds (5; 105) with heterogeneous catalyst, each bed supported by a catalyst support grating (6; 106); a vapour collection chamber (9; 109) and a vapour redistribution chamber (10; 110) between successive pair(s) of beds for redistribution of vapourous reaction mixture over the inlet of the next bed; a diaphragm (11; 111) separating the vapour collection chamber (9; 109) from the vapour redistribution chamber; at least one pair of nested trough members extending at least partially across the diaphragm, each comprising an inner trough member (14; 114) having one or more apertures (18; 118), an outer trough (20; 120) having one or more apertures (21; 121) and a quench gas conduit (15; 115) provided with apertures (17; 117); the apertures (18; 118; 21; 121; 17; 117) arranged to provide
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: March 6, 2001
    Assignee: Kvaerner Process Technology Limited
    Inventors: Simon Robert Early, George Edwin Harrison, John Wilson Kippax
  • Patent number: 6197272
    Abstract: The present invention relates to a method for manufacturing transition metal carbides and/or transition metal carbonitrides and the use thereof together with novel transition metal xerogels.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: March 6, 2001
    Assignee: Bayer AG
    Inventors: Hermann-Jens Womelsdorf, Gerd Passing, Nils Perchenek
  • Patent number: 6197273
    Abstract: The invention provides a process for production of fine spherical particles of a carbonate or a hydroxide of nickel, cobalt or copper which comprises: dissolving a carbonate or a hydroxide of nickel, cobalt or copper having the general formula (I) M(CO3)x/2.(OH)y wherein M represents Ni, Co or Cu, and x and y are numerals satisfying the followings: 0≦x≦2, 0≦y≦2 and x+y=2, in aqueous ammonia, converting the resulting solution to a W/O emulsion containing droplets of the solution in a non-aqueous medium, and then removing volatile components including ammonia from within the droplets, thereby precipitating a basic carbonate or a hydroxide of a metal selected from nickel, cobalt and copperin the droplets.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: March 6, 2001
    Assignee: Sakai Chemical Industry Co., Ltd.
    Inventors: Kazuhiko Nagano, Kazunobu Abe, Shigefumi Kamisaka, Kiyoshi Fukai, Tsutomu Hatanaka, Shinji Ohgama, Hiroshi Nakao, Minoru Yoneda, Hideto Mizutani
  • Patent number: 6197274
    Abstract: Silica coated carbon blacks are disclosed and can be prepared by coating a fine dispersion of carbon black, such as a carbon black having an attached organic group(s). Compositions and articles of manufacture, including elastomeric compositions, containing such carbon black are also disclosed.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: March 6, 2001
    Assignee: Cabot Corporation
    Inventors: Khaled Mahmud, Meng-Jiao Wang, James A. Belmont, Steven R. Reznek
  • Patent number: 6197275
    Abstract: The active phase of a catalyst composition contains at least one bismuth oxide compound in which bismuth is present at least partly in oxidation state +5, the bismuth oxide compound furthermore containing at least one basic metal component stabilizing the oxidation state +5, and said catalyst composition is used in oxidation and dehydrogenation reactions under heterogeneous catalysis, in particular the preparation of chlorine from hydrogen chloride.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: March 6, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Alfred Hagemeyer, Andreas Püttner, Martin Trömel
  • Patent number: 6197276
    Abstract: Hydrated aluminium compounds of the present invention are represented by the general formula nS, mM, Al2O3, xH2O where S is a surfactant or a group of surfactants, n is the number of moles of S, M is an alkaline cation, preferably selected from the group formed by Na+, K+, NH4+, m is the number of moles of M and x is the number of moles of water. The hydrated compounds are obtained from inorganic aluminium sources which are in the form of cation-monomers and/or cation-oligomers. The surfactants are anionic and/or non-ionic surfactants. When the group of surfactants comprises at least one anionic surfactant, at least one cationic surfactant can optionally be added.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: March 6, 2001
    Assignee: Institut Francais du Petrole
    Inventors: Frédéric Kolenda, Jean-Louis Guth, Sabine Valange, Zelimir Gabelica, Eric Benazzi
  • Patent number: 6197277
    Abstract: Alumina particles having high dispersibility and plasticity, at least on the surface of which a phosphoric acid or phosphate is present and suitable for use as a material for pigments for paints, precision abrasives or ceramics. The alumina particles are produced by adding a crystallization inhibitor containing at least phosphate ion to aluminum hydroxide or alumina hydrate and then conducting a hydrothermal synthesis treatment. The amount of the phosphate ion to be added is in the range of 3.0×10−3 to 2.5×10−2 mol per mol of aluminum hydroxide or alumina hydrate. The particle size of aluminum hydroxide or alumina hydrate is 0.1 to 5.0 &mgr;m. The hydrothermal synthesis is preferably conducted at 350° C. or above under a pressure of 50 to 200 atm and at a temperature elevation rate of 5° C./min to 0.3° C./min. The thus obtained alumina is &agr;-alumina in the form of hexagonal plate single crystal having a particle size of 0.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: March 6, 2001
    Assignee: YKK Corporation
    Inventors: Takeshi Fukuda, Ryuichi Shido
  • Patent number: 6197278
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: March 6, 2001
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. William Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Patent number: 6197279
    Abstract: The present invention provides a method of delivering an emulsion or suspension containing a supersaturated gas into a gas-depleted environment. The method generally comprises the steps of preparing an emulsion or suspension, exposing the emulsion or suspension to a gas at a pressure greater than 2 bar, and delivering the emulsion or suspension to a gas-depleted environment at ambient pressure.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: March 6, 2001
    Assignee: Wayne State University
    Inventor: J. Richard Spears
  • Patent number: 6197280
    Abstract: A device for providing pharmaceutical doses comprising a container, filed with a pharmaceutical composition including glyceryl trinitrate and 1,1,1,2-tetrafluoroethane, or 1,1,1,2,3,3,3-heptafluoropropane, as a propellant, and a valve arranged for delivering aerosol doses of said pharmaceutical composition to the exterior of the container, wherein at least a portion of the device is formed from a polyester.
    Type: Grant
    Filed: July 13, 1999
    Date of Patent: March 6, 2001
    Assignee: Bioglan Laboratories Limited
    Inventors: Michael Goodman, David John Howlett
  • Patent number: 6197281
    Abstract: The sunscreen or makeup may be applied to a person who is wet, or even underwater, yet it will provide the fill efficacy which it would have had had it been applied to the person when their skin was dry. In addition, it will be effective from the time that it is first applied, so no waiting period is required, as was the case for the so-called “water resistant” and “waterproof” sunscreens of the prior art. A series of test procedures which illustrate the efficacy of the “wet-appliable” sunscreens of the present invention are disclosed.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: March 6, 2001
    Inventors: Ernest Glading Stewart, Kenneth Klein
  • Patent number: 6197282
    Abstract: The present invention provides a method for producing a material dispersed with ultraviolet shielding fine particles, characterized by subjecting a starting material liquid mixture comprising particles comprising one or more inorganic substances having shielding abilities against ultraviolet light, one or more silicone dispersants selected from modified silicones and reactive silicones, and a silicone oil to a mill treatment and/or a high-pressure dispersion treatment; and ultraviolet shielding fine particles or a material dispersed therewith, characterized by being produced by the above method. Also, the present invention provides a method of producing a powdery product of ultraviolet shielding fine particles, characterized by drying the material dispersed with ultraviolet shielding fine particles obtainable by the above method.
    Type: Grant
    Filed: November 20, 1998
    Date of Patent: March 6, 2001
    Assignee: Kao Corporation
    Inventors: Kentaro Oshima, Shunji Kozaki, Yoshinobu Imaizumi, Toshio Miyake, Keiichi Tsuto, Kazuhiro Yamaki, Satoshi Sugawara
  • Patent number: 6197283
    Abstract: W/O emulsions comprising dispersed therein crosslinked, water-swellable polymers consisting of a) 35-100% by weight of ionic monomers, b) 0-65% by weight of nonionic monomers, c) 0.3-1 mol-%, based on a) and b), of at least one at least bifunctional monomer, where the oil phase consists of one or more fatty acid esters, are used as thickeners in cosmetic or pharmaceutical formulations.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: March 6, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Kristin Tiefensee, Volker Schehlmann, Martin Rübenacker
  • Patent number: 6197284
    Abstract: Lipcolor comprising a salt or hydroxide of di-or trivalent metal, a water-soluble alginate, a red or orange lake color having a COONa or COOK group, and an oil coponent having appearance of liquid at 20° C. The lipcolor less yields a dry feeling or an uneasy feeling with the passage of time, and its color comes off less in friction with foods and drinks.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: March 6, 2001
    Assignee: Kanebo, Ltd.
    Inventor: Nobumasa Sato
  • Patent number: 6197285
    Abstract: A clear cosmetic gel composition comprising: (a) an aqueous phase comprising: (i) water, and (ii) at least one cosmetically active ingredient; (b) a coupling agent; (c) an oil phase comprising: (i) a silicone-containing solvent, and (ii) an isoparaffin solvent having a boiling range between about 100 to 340° C., wherein the isoparaffin constitutes between about 1 to 75% by weight, of the total of the oil phase; and (d) silicone-containing surfactant.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: March 6, 2001
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Ralph M. Kowalik, Karen K. Kuo, Philip Merchant, Jr.
  • Patent number: 6197286
    Abstract: Disclosed are anhydrous cosmetic compositions comprising from about 0.01% to about 60% by weight of a cosmetic active; from about 10% to about 90% by weight of a liquid carrier; and from about 1% to about 60% by weight of a solid, polymorphic, unsubstituted, triglyceride gellant characterized by &bgr;′-2 crystalline order within the compositions. These compositions can be formulated as hard sticks, soft solids or creams, and have improved high temperature texture and phase stability and maintain product hardness even after exposure to high and then low storage temperatures.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: March 6, 2001
    Assignee: The Procter & Gamble Company
    Inventors: Timothy Alan Scavone, James David Landgrebe
  • Patent number: 6197287
    Abstract: Composition comprising an oil phase, an aqueous phase, at least one emulsifier of water-in-oil (W/O) type, at least one emulsifier of oil-in-water (O/W) type, characterized in that the composition is an inverted latex comprising from 20% to 60% by weight, and preferably from 25% to 45% by weight, of a branched or crosslinked anionic polyelectrolyte based on at least one monomer possessing a strongly acidic function, copolymerized either with at least one monomer possessing a weakly acidic function or with at least one neutral monomer. The compositions have cosmetic applications.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: March 6, 2001
    Assignee: Societe d'Exploitation de Produits pour les Industries Chimiques Seppic
    Inventors: Paul Mallo, Guy Tabacchi, Jean-Pierre Boiteux
  • Patent number: 6197288
    Abstract: This invention pertains to a malodor counteractant composition comprising a malodor counteractant agent in an oral vehicle. The malodor counteractant agent is selected from the group consisting of, in percentages by weight: (A) (a) geranyl propionate; (b) benzyl benzoate; and (c) neryl acetate; (B) (a) citronellyl acetate; (b) benzyl benzoate; and (c) neryl acetate; (C) (a) benzyl benzoate; (b) geranyl propionate; and (c) citronellyl acetate; (D) (a) geranyl propionate; (b) citronellyl acetate; and (c) benzyl benzoate; (E) (a) citronellyl acetate; and (b) geranyl propionate; (F) (a) benzyl benzoate; and (b) neryl acetate; (G) (a) benzyl benzoate; (b) neryl acetate; (c) trimethyl (2,6,6) vinyl(6) tetrahydropyran; (d) citronella oil; and (e) and ethyl alcohol; and (H) (a) benzyl benzoate; (b) neryl acetate; (c) citronella oil; (d) geranyl acetate; (e) alpha ionone; (f) geranyl propionate; (g) linalool; and (e) and ethyl alcohol.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: March 6, 2001
    Assignee: Bush Boake Allen, Inc.
    Inventor: Amrit Singh Mankoo
  • Patent number: 6197289
    Abstract: An apparatus for removing a biologically active agent from body fluid that includes an inlet for receiving body fluid, a substrate that includes the reaction product of a substantially water insoluble polymer and a polyalkylene imine, the polyalkylene imine being in a form capable of binding a biologically active agent in the body fluid, and an outlet through which the body fluid flows following contact with the substrate.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: March 6, 2001
    Assignee: Terumo Cardiovascular Systems Corporation
    Inventors: David F. Wirt, Lary M. Sirvio
  • Patent number: 6197290
    Abstract: Disclosed are cholesterol-depressant, coated or non-coated tablets for oral administration, which comprise an anion exchange resin of formula (I): wherein X represents a physiologically-acceptable counter ion; and p represents an average degree of polymerization, and is larger than 10,000, silicon dioxide and crystalline cellulose, but not containing water. The non-coated tablets are preferably coated with cellulosic substances. The tablets are easy to take, as being not bitter. The dose of the tablets can be decreased, since the tablets can contain a large amount of the active ingredient. The mixture comprising the constituent components can be directly tabletted in the absence of water.
    Type: Grant
    Filed: January 13, 1999
    Date of Patent: March 6, 2001
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Takeshi Goto, Tatsuya Meno
  • Patent number: 6197291
    Abstract: The inventors provide an agent for potentiating the effect of interleukin-8, which comprises dehydroepiandrosterone sulfate or a pharmaceutically acceptable salt thereof as an active ingredient. An agent for potentiating the effect of IL-8 of the present invention potentiates the effect of IL-8 by activating the receptor of IL-8 and increasing the number of receptors.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: March 6, 2001
    Assignees: Kanebo Limited, Akzo Nobel N.V.
    Inventors: Toshihiko Terao, Naohiro Kanayama
  • Patent number: 6197292
    Abstract: The present invention relates to a therapeutic agent, composed of canine interferon-&ggr;, for canine intractable dermatitis and a treatment for canine intractable dermatitis using the agent.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: March 6, 2001
    Assignee: Toray Industries, Inc.
    Inventors: Tomiya Uchino, Katsushige Yamada, Fumiyoshi Okano, Masahiro Satoh, Isao Kawakami
  • Patent number: 6197293
    Abstract: Replication-competent adenovirus vectors specific for cells which allows a probasin transcriptional response element (PB-TRE) to function, such as cells which express the androgen receptor (AR), and methods of use of such viruses are provided. These viruses comprise an adenoviral gene under control of a transcriptional regulatory portion of a PB-TRE, which is in turn dependent upon AR expression. The gene can be, for example, a gene required for viral replication or the adenovirus death protein gene (ADP). The viruses can also comprise at least one additional adenoviral gene under control of at least one additional prostate-specific transcriptional response element, such as that controlling prostate-specific antigen expression (PSA-TRE). Thus, virus replication can be restricted to target cells exhibiting prostate-specific gene expression, particularly prostate carcinoma cells.
    Type: Grant
    Filed: March 2, 1998
    Date of Patent: March 6, 2001
    Assignee: Calydon, Inc.
    Inventors: Daniel R. Henderson, Eric R. Schuur, De-Chao Yu
  • Patent number: 6197294
    Abstract: This invention provides cells containing recombinant polynucleotides coding for cell surface molecules that, when expressed in the cell, result in rejection of the cell by the host immune system. The invention also provides methods of using such cells, and capsules for delivery of biologically active molecules to a patient.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: March 6, 2001
    Assignee: Neurotech S.A.
    Inventors: Weng Tao, Shou Wong, William F. Hickey, Joseph P. Hammang, E. Edward Baetge
  • Patent number: 6197295
    Abstract: The present invention solves the need for non-toxic forms of selenium which is an essential part of the human diet. This invention provides novel dried-yeast products containing selenium as well as a method of producing the dried yeast products. The method uses selenium having high biological activity but low toxicity. The invention also provides nutritional supplements containing the novel selenium containing dried yeast products and methods of administering these products and supplements to improve human health. The invention also provides a practically non-toxic yeast selenium product having increased intracellular selenium concentrations and methods to reduce tumor cell growth by administration of a selenium yeast product comprising yeast Saccharomyces boulardii sequela PY 31 (ATCC 74366) in combination with chemotherapeutic agents.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: March 6, 2001
    Assignee: Viva America Marketing Corporation
    Inventors: Houn Simon Hsia, Ping Yang, Michael Arnold
  • Patent number: 6197296
    Abstract: A method of forming a tissue equivalent is described. A length of polyester tube is threaded over a mandrel (H) and attached at either end by clips at A and D. A block (F) is then screwed into place. The polyester is then pre-soaked by injecting through Tap (2) an acidified collagen solution for approximately one hour. After a suitable period of time the excess solution is aspirated off. Following this stage, a second, alkaline solution is injected into the apparatus which contains smooth muscle cells (SMC). Thus, neutralisation of the collagen impregnated within the fabric of the tube occurs leading to spontaneous fibrillogenesis within the interstices of the cloth, eliminating the risk of delamination. The apparatus is then incubated. The collagen contracts down onto the fabric tube and the cell-impregnated gel becomes incorporated into the presoaked collagen. The pre-impregnated collagen and the collagen provided in the aqueous mixture contract down as one into a coherent whole with the SMC.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: March 6, 2001
    Assignee: National Heart Research Fund
    Inventors: Alban Davies, Sarah Haynes, Tom Browne, John Kearney
  • Patent number: 6197297
    Abstract: A monoclonal antibody which is specific to a polypeptide having a molecular weight of 18, 500±3,000 daltons on SDS-PAGE and a pI of 4.9±1.0 on chromatofocusing. The monoclonal antibody is obtainable from hybridomas and can be used for the purification and detection of the polypeptide. The polypeptide strongly induces the IFN-&ggr; production by immunocompetent cells with only a small amount, and does not cause serious side effects even when administered to human in a relatively-high dose.
    Type: Grant
    Filed: November 15, 1995
    Date of Patent: March 6, 2001
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Toshio Kunikata, Mutsuko Taniguchi, Keizo Kohno, Masashi Kurimoto