Patents Issued in July 3, 2007
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Patent number: 7238301Abstract: There is provided herein cross-linked, phosphorescent micro- and nano-particles and applications of those particles. The invention uses halogen-containing polymers and co-polymers (HCPs) as an encapsulation matrix for organic and organometallic phosphorescent compounds to form micro- or nano-particles. The phosphorescence of these encapsulated phosphorescent particles is substantially unaffected by phosphorescence quenchers such as oxygen and water molecules at ambient conditions. The invention provides methods of making cross-linked phosphorescent particles. HCPs may be directly cross-linked through linking moieties that are a part of the polymer, or cross-linked through other separate bridging or cross-linking materials Cross-linked particles are more stable than the non-cross-linked counterparts and more resistant to temperature, surfactants, and organic solvents.Type: GrantFiled: June 29, 2004Date of Patent: July 3, 2007Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Lei Huang, Xuedong Song, Bin Wu, Rosann Marie Kaylor
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Patent number: 7238302Abstract: The present invention is a single-component, UV-emitting phosphor having a composition represented by the general formula (Y1?x?y?zLaxGdyCeZ)PO4 where x has a value in a range from 0.001 to 0.98, y has a value in a range from 0 and 0.1, z has a value in a range from 0.01 and 0.2, and x+y+z<1. The phosphor when stimulated by 254 nm radiation emits in both the UVA and UVB regions. The relative balance of the UVA and UVB emissions may be varied by adjusting the relative amounts of Y and La. Brightness can be increased by adding Gd to the composition.Type: GrantFiled: December 28, 2004Date of Patent: July 3, 2007Assignee: Osram Sylvania Inc.Inventors: Chen-Wen Fan, Thomas M. Snyder, Eric A. Thomason
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Patent number: 7238303Abstract: Phosphor and a plasma display device are provided whose deterioration in brightness of phosphors and a degree of change in chromaticity are alleviated and whose discharge characteristics are improved and that has excellent initial characteristics. Phosphor of the present invention is an alkaline-earth metal aluminate phosphor containing an element M (where M denotes at least one type of element selected from the group consisting of Nb, Ta, W and B). In this phosphor, a concentration of M in the vicinity of a surface of the phosphor particles is higher than the average concentration of M in the phosphor particles as a whole. A plasma display device according to the present invention includes a plasma display panel in which a plurality of discharge cells in one color or in a plurality of colors are arranged and phosphor layers are arranged so as to correspond to the discharge cells in colors and in which light is emitted by exciting the phosphor layers with ultraviolet rays.Type: GrantFiled: August 27, 2004Date of Patent: July 3, 2007Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Kojiro Okuyama, Takehiro Zukawa, Masahiro Sakai, Seigo Shiraishi, Kazuhiko Sugimoto, Masaki Aoki, Junichi Hibino
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Patent number: 7238304Abstract: As a green light emitting phosphor capable of emission upon excitation with light having a wavelength of 350 to 500 nm, characterized in containing Tb3+ ions as emission ions in high concentrations without causing concentration quenching, the present invention provides a green light emitting phosphor capable of emission upon excitation with light having a wavelength of 350 to 500 nm, characterized by having a composition represented by the compositional formula (1): ATbxLn(1-x)M2O8??(1) wherein A is at least one element selected from the group consisting of Li, Na, K, and Ag, Ln is at least one element selected from rare earth elements including Y and excluding Tb, M is at least one element selected from the group consisting of Mo and W, and x is a positive number satisfying 0.4?x?1, and a light emitting device incorporated with the green light emitting phosphor.Type: GrantFiled: August 2, 2004Date of Patent: July 3, 2007Assignee: Kabushiki Kaisha Fine Rubber KenkyuushoInventor: Tsutomu Odaki
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Patent number: 7238305Abstract: A sol-gel material with metal particles which can be used as a conductive adhesive for systems that have a high operating temperature is disclosed. The material is especially suitable for appliances equipped with a flat heating element, such as steam irons.Type: GrantFiled: April 5, 2004Date of Patent: July 3, 2007Assignee: Koninklijke Philips Electronics N.V.Inventors: Sandor Nemeth, Marcel Rene Boehmer, Gerard Cnossen
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Patent number: 7238306Abstract: Tribocharging-reducing conformal coating are provided for a flexible circuit, which reduce tribocharge voltage of a coated flexible circuit to less than about 15V, preferably less than about 10 V. Coating formulations include at least about 1% of a polypyrrole. Flexible circuits having a tribocharge voltage of less than about 15V, preferably less than about a 10V comprise at least one polymeric dielectric substrate, and a conductive layer formed thereon including at least one conductive element such as a trace, bond pad and/or a lead device, and a layer of a conformal coating wherein the conformal coating comprising at least about 1% of a polypyrrole compound.Type: GrantFiled: August 11, 2004Date of Patent: July 3, 2007Assignee: Innovex, Inc.Inventor: Eric E. Ries
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Patent number: 7238307Abstract: A method is disclosed for pre-conditioning inserts for improved replication during injection molding. The pre-conditioned inserts provide improved bonding with the injection-material and improved replication of complex molding surfaces. The pre-conditioning of the inserts comprises placing the insert in position against the molding surface, followed by heat-soaking the insert. Heat-soaking can be accomplished using infrared energy, preferably broadband infrared energy or energy that is preferentially absorbed by the insert.Type: GrantFiled: June 20, 2003Date of Patent: July 3, 2007Assignee: Younger Mfg. Co.Inventors: Jotinderpal S. Sidhu, Andrew J. McKenzie, Ahmad A. Barzak, Nancy L. S. Yamasaki
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Patent number: 7238308Abstract: A process form producing ceramic composites comprising metal carbides, which comprises the steps production of a porous carbon-containing intermediate body, infiltration of the intermediate body with the melt of a carbon-forming metal, reaction of at least part of the carbon of the intermediate body with the carbide-forming metal to form a metal carbide, with at least part of the carbide-formed metal being supplied via at least one wick made of porous carbon material having pore channels and the wick being produced by carbonization of wood materials or of essentially unidirectionally reinforced CFRP, such wicks and their use in the abovementioned process.Type: GrantFiled: March 14, 2003Date of Patent: July 3, 2007Assignee: Audi AGInventor: Jens Rosenloecher
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Patent number: 7238309Abstract: An apparatus for orienting section of a plasticized ceramic extrudate includes a marking assembly for applying an orientation reference mark to a plasticized ceramic extrudate exiting an extrusion die onto an extrudate support, and at least one extrudate-contacting deformable roller having an axis of rotation, wherein the axis of rotation is pivotable with respect to a movement of the extrudate exiting an extrusion die, and wherein the roller is adapted to contact the extrudate and correct a corkscrew deformation of the extrudate exiting the extrusion die. The apparatus also includes at least one extrudate-contacting orientation control member for correcting the orientation of a cut section of the extrudate on the extrudate support in response to a misalignment of the reference mark.Type: GrantFiled: October 21, 2003Date of Patent: July 3, 2007Assignee: Corning IncorporatedInventors: Scott L Adriaansen, Kim F Cobb-Cain, Kevin B Sterner
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Patent number: 7238310Abstract: The invention relates to the use of gelation moulds made from hydrophobicized glass tubes for the production of monolithic mouldings as sorbents for chromatography.Type: GrantFiled: May 23, 2001Date of Patent: July 3, 2007Assignee: Merck Patent GmbHInventors: Dieter Lubda, Karin Cabrera
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Patent number: 7238311Abstract: A material comprising aerogel particles and a polytetrafluoroethylene (PTFE) binder is formed having a thermal conductivity of less than or equal to 25 mW/m K at atmospheric conditions. The material is moldable or formable, having little or no shedding of filler particles, and may be formed into structures such as tapes or composites, for example, by bonding the material between two outer layers. Advantageously, composites may be flexed, stretched, or bent without significant dusting or loss of insulating properties.Type: GrantFiled: May 5, 2006Date of Patent: July 3, 2007Assignee: Gore Enterprise Holdings, Inc.Inventors: Cedomila Ristic-Lehmann, Brian Farnworth, Anit Dutta
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Patent number: 7238312Abstract: An apparatus is adapted to form a plurality of apertures in a panel made from a meltable foamed plastic material. The apparatus has a movable panel support device for supporting said panel and a heating array. The heating array has a plurality of heating elements mounted to a support frame. The heating array is disposed opposite to the panel support device. Each of the heating elements is adapted to emit sufficient heat to melt the foamed plastic material when a panel is positioned proximate the heating elements. A driving mechanism is provided for moving the panel support device toward and away from said plurality of heating elements. The panel supporting device moves a panel supported thereon, towards and away from the plurality of heating elements and during them movement melts a plurality of apertures in the panel.Type: GrantFiled: December 2, 2002Date of Patent: July 3, 2007Inventor: Leonid G. Bravinski
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Patent number: 7238313Abstract: The present invention is directed to the combined use of first and second fatty acid amides to improve the softness of a thermoplastic polymer construct. A combination of fatty acid amides is provided in the blend ratio of about 10 to 90 percent by weight of a first fatty acid amide and 90 to 10 percent by weight of a second fatty acid amide. The first and second fatty acid amides are compounded into a thermoplastic polymer carrier resin and, preferentially, produced as concentrate pellets containing 0.5 to 75 percent by weight total fatty acid amide loading. The concentrate pellets are introduced into a thermoplastic polymer base, to form a thermoplastic resin, at a letdown level in the range of about 1 to 15 percent, with the range of 2 to 10 percent being preferred, and the range of 3 to 6 percent being most preferred.Type: GrantFiled: August 7, 2002Date of Patent: July 3, 2007Assignee: Polymer Group, Inc.Inventors: Richard Ferencz, Robert Dale, Nick Carter, Lei Wang
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Patent number: 7238314Abstract: Composite webs having one or more polymeric structures located on a substrate, methods of manufacturing the composite webs, and systems for manufacturing the composite webs are disclosed. The polymeric structures are formed using thermoplastic compositions deposited into one or more depressions on a forming tool. The forming tool is maintained at a temperature that is below the melt processing temperature of the thermoplastic composition.Type: GrantFiled: March 13, 2003Date of Patent: July 3, 2007Assignee: 3M Innovative Properties CompanyInventors: Byron M. Jackson, Randall L. Alberg, Dennis L. Becker, Roger D. Pavlis, Leigh E. Wood
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Patent number: 7238316Abstract: Precisely configured, especially of geometric shape, flakes of liquid crystal material are made using a mechanically flexible polymer mold with wells having shapes which are precisely configured by making the mold with a photolithographically manufactured or laser printed master. The polymer liquid crystal is poured into the wells in the flexible mold. When the liquid crystal material has solidified, the flexible mold is bent and the flakes are released and collected for use in making an electrooptical cell utilizing the liquid crystal flakes as the active element therein.Type: GrantFiled: March 7, 2003Date of Patent: July 3, 2007Assignee: University of RochesterInventors: Anka Trajkovska-Petkoska, Stephen D. Jacobs, Tanya Z. Kosc, Kenneth L. Marshall
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Patent number: 7238317Abstract: A twin-wall pipe comprises an internal pipe and an external pipe. The external pipe is corrugated, having elevations and troughs. The twin-wall pipe is further provided with a socket. In a transition portion towards the twin-wall pipe and the socket, provision is made for at least one overflow passage which interconnects the clearance between the external pipe and internal pipe in the vicinity of the transition portion and an adjacent elevation.Type: GrantFiled: November 30, 2004Date of Patent: July 3, 2007Inventor: Ralph Peter Hegler
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Patent number: 7238318Abstract: The side wall portion of a plastic article, as a plastic container, is opaque and includes a transparent portion, as a view stripe. The opaque portion limits viewing the inside of the article, whereas the transparent portion permits viewing the inside of the article therethrough. A method for forming the plastic article is also disclosed.Type: GrantFiled: April 25, 2005Date of Patent: July 3, 2007Assignee: Plastipak Packaging, Inc.Inventors: Marc A. Pedmo, Thomas J. Simpson, Michael J. Sainato
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Patent number: 7238319Abstract: A method for fabricating a green ceramic article containing organic compounds. The method involves first heating the green ceramic article to sequentially remove the organic compounds such that the organic compound with the lowest weight loss onset temperature is substantially removed prior to the next higher weight loss onset temperature organic compound. The organic compounds include but are not limited to at least an oil or oil-based compound having a flash point or an ignition temperature, higher than the weight loss onset temperature. For this system the temperature during heating is maintained below the flash point of the oil or oil-based compound until substantial removal thereof from the green ceramic structural body. After the organic compounds are substantially removed, the green ceramic article is further fired to a temperature and for a time to obtain a final fired body.Type: GrantFiled: June 26, 2003Date of Patent: July 3, 2007Assignee: Corning IncorporatedInventors: John H. Brennan, Gregory P. Dillon, Tudor C. Gheorghiu, Michael J. Vayansky
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Patent number: 7238320Abstract: A device for oxygenating blood in an extracorporeal circuit includes a first structure suitable to delimit a portion of space-containing capillaries made of microporous membrane. The capillaries convey oxygen and are wet externally by blood flowing through a portion of space between an intake connector, which is connected to a venous line of the extracorporeal circuit, and a delivery connector. The device includes a second structure monolithically connected and contiguous to the first structure. The second structure is suitable to contain blood filtration means that divide the portion of space delimited thereby into a blood distribution chamber, provided with an air vent and connected to the delivery connector of the first structure, and a blood collection chamber provided with a delivery connector connected to the arterial line of the extracorporeal circuit.Type: GrantFiled: March 19, 2004Date of Patent: July 3, 2007Assignee: Sorin Group Italia S.r.l.Inventors: Nicola Ghelli, Edgardo Costa Maianti, Ivo Panzani
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Patent number: 7238321Abstract: A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such a DNA polymerase chain reaction. Biological samples are placed in glass micro capillary tubes and then located inside the sample chamber. A programmable controller regulates the temperature of the sample inside the sample chamber. Once a heating cycle is completed, the controller opens a door to the chamber for venting hot air out and cool ambient air is moved in. Temperature versus time profiles corresponding to optimum denaturation, annealing and elongation temperatures for amplification of DNA are achieved by the present invention.Type: GrantFiled: July 13, 2004Date of Patent: July 3, 2007Assignee: University of Utah Research FoundationInventors: Carl T. Wittwer, David R. Hillyard
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Patent number: 7238322Abstract: A self-contained apparatus using a gravitationally encouraged, interrupted, downward, diffusive and programmed flow of fluid to provide for rapid confirmatory immunological testing (“RCIT”) in, for example, a clinical, point-of-care setting. A fluid specimen such as blood, saliva or urine is deposited into a first chamber carrying a source of conjugate having mobilizable binding members such as immunographic antigens or antibodies specific to the condition being tested conjugated to a detectable label such as colloidal gold. The specimen is premixed with a first measured, reactive mix buffer solution carried within an openable tank. The specimen and solution are temporarily held within an incubation reservoir formed behind a dam made from porous, diffusive material.Type: GrantFiled: October 26, 2005Date of Patent: July 3, 2007Assignee: DNT Scientific Research, LLCInventors: Naishu Wang, David F. Zhou
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Patent number: 7238323Abstract: Integrated systems, apparatus, software, and methods for performing biochemical analysis, including DNA sequencing, genomic screening, purification of nucleic acids and other biological components and drug screening are provided. Microfluidic devices, systems and methods for using these devices and systems for performing a wide variety of fluid operations are provided. The devices and systems of are used in performing fluid operations which require a large number of iterative, successive or parallel fluid manipulations, in a microscale, or sealed and readily automated format.Type: GrantFiled: December 5, 2002Date of Patent: July 3, 2007Assignee: Caliper Life Sciences, Inc.Inventors: Michael Knapp, John Wallace Parce, Luc J. Bousse, Anne R. Kopf-Sill
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Patent number: 7238324Abstract: A microfluidic device for controlling the flow of a micro amount of fluid is provided. The microfluidic device is manufactured by binding a sensing substrate including a sensing electrode, an electrode interconnect, and a electrode pad, with a channel substrate including at least two fluid inlet ports, a chamber, and a channel, wherein a first fluid injected via one of the fluid inlet ports flows by natural capillary force, and a second fluid injected via another fluid inlet port is forced to flow by an external pump. The microfluidic device controls fluid flow and flow stoppage by a combination of natural capillary flow and an externally applied pressure as a result of the action of a pump.Type: GrantFiled: July 7, 2003Date of Patent: July 3, 2007Assignee: Electronics and Telecommunications Research InstituteInventors: Jong Soo Ko, Hyun Chul Yoon, Hae Sik Yang, Dae-Sik Lee, Kwang Hyo Chung, Hyeon Bong Pyo, Sung Jin Kim, Yun Tae Kim
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Patent number: 7238325Abstract: There is provided a micro chemical device with a valve function for which the pressure resistance is high and the channel cross-sectional area does not depend on the fluid pressure, and which furthermore enables the suppression of the adsorption of biological matter and yet is easy to produce, as well as a flow regulation method using such a device. This has a valve function, in which a member (B) is bonded to a member (A) with a groove in the surface thereof, via the surface of the member (A) in which the groove is formed, a capillary type channel of width from 1 to 1000 ?m and height from 1 to 1000 ?m is formed by the groove of the member (A) and the member (B) at the bonding surface between the member (A) and the member (B), a cavity section is formed partway along the channel and the width of this cavity section is from 0.Type: GrantFiled: March 1, 2001Date of Patent: July 3, 2007Assignee: Kawamura Institute of Chemical ResearchInventors: Takanori Anazawa, Atsushi Teramae
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Patent number: 7238326Abstract: There is disclosed a germicidal treatment system having a status indicator. The germicidal treatment system comprises at least one mounting assembly attachable to an outside of a wall of an air handling apparatus. Each of the mounting assemblies includes a germicidal lamp and a ballast. The germicidal lamp is coupled to the ballast. The germicidal treatment system includes a power cord to receive electrical power and to provide electrical power to the ballast. A status indicator to indicate the functioning status of the germicidal treatment system.Type: GrantFiled: April 24, 2003Date of Patent: July 3, 2007Assignee: Steril-Aire, Inc.Inventor: Kanghong Zhang
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Patent number: 7238327Abstract: A catalytic converter and method for its assembly including an external shell formed in two halves containing a catalytic substrate, two internal shields and two-piece inlet and outlet cones. The inlet and outlet cones are attached as halves to each side of the external shell, and are assembled to each other as the external shells are assembled.Type: GrantFiled: December 10, 2002Date of Patent: July 3, 2007Assignee: Automotive Components Holdings, LLCInventors: Carl Irving, Joseph Michael Lanzesira, Chris Darr, Houliang Li, Darren Nance
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Patent number: 7238328Abstract: A solid-state light source photolytic NO2 converter including a reaction chamber made of a reflective material with diffuse reflective properties, whereby the reaction chamber includes a low volume gas cell wherein the gas sample residence time is less than 5 seconds is provided. The NO2 in the air sample is exposed to ultraviolet radiation at wavelengths less than 420 nm, whereby the NO2 is converted to NO. The NO is subsequently measured using an NO analyzer. The solid-state light source includes diode lasers and LED's that emit UV wavelength in the range of 350–420 nm. The use of a narrow wavelength range afforded by the solid-state light source results in an interference-free conversion of NO2 to NO at high efficiency.Type: GrantFiled: December 6, 2002Date of Patent: July 3, 2007Assignee: Sonoma Technology, Inc.Inventor: Martin Patrick Buhr
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Patent number: 7238329Abstract: A device located between two successive granular beds (203) and (205) for injecting a secondary fluid can produce and distribute a polyphase mixture between said secondary fluid and a fluid or mixture of fluids originating from the upper granular bed and comprises a chamber for injecting a secondary fluid (201), the secondary fluid being injected into said device, and means (204) for bringing said secondary fluid into contact with at least a portion of the fluid or mixture of fluids originating from the upper granular bed (203) and for simultaneous distribution (208) of the mixture resulting from said contact to the lower granular bed (205).Type: GrantFiled: August 16, 2001Date of Patent: July 3, 2007Assignee: Institut Francais du PetroleInventors: Christophe Boyer, Vincent Coupard, Bertrand Fanget
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Patent number: 7238330Abstract: A vapor decontamination system for decontaminating a defined region. The system is comprised of a chamber defining a region, and a generator for generating vaporized hydrogen peroxide from a solution of hydrogen peroxide and water. A closed loop circulating system is provided for supplying the vaporized hydrogen peroxide to the region. A destroyer within the closed loop circulating system breaks down the vaporized hydrogen peroxide. A bypass conduit is provided to bypass the destroyer. A controller causes vaporized hydrogen peroxide from the generator to bypass the destroyer during a predetermined phase of operation.Type: GrantFiled: October 21, 2003Date of Patent: July 3, 2007Assignee: Steris Inc.Inventors: Aaron L. Hill, Michael A. Bacik
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Patent number: 7238331Abstract: The present invention discloses a process for producing nano-powders and powders of nano-particle loose aggregate, which includes: (a) providing at least two reactant solutions A and B capable of rapidly reacting to form deposits; (b) supplying the at least two reactant solutions A and B at least at the reaction temperature into a mixing and reaction precipitator respectively, in which mixing reaction and precipitation are continuously carried out in sequence, the mixing and reaction precipitator being selected from at least one of a tubular ejection mixing reactor, a tubular static mixing reactor and an atomization mixing reactor; and (c) treating the deposit-containing slurry continuously discharged from the mixing reaction precipitator.Type: GrantFiled: July 26, 2002Date of Patent: July 3, 2007Assignee: Anshan University of Science and TechnologyInventors: Yingyan Zhou, Shoushan Gao, Kaiming Wang, Chuangeng Wen, Xiaoqi Li
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Patent number: 7238332Abstract: A material for filtering NO2 and nitric acid vapors from air over a wide range of humidities and temperatures including a porous hydrophobic substrate and an amine is provided.Type: GrantFiled: June 14, 2004Date of Patent: July 3, 2007Inventors: William B. Feaver, Christopher J. Karwacki, Joseph A. Rossin
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Patent number: 7238333Abstract: A method of reducing an amount of carbon monoxide in process fuel gas in a water gas shift converter with no methane formation. The method includes placing a high activity water gas shift catalyst system into a water gas shift converter; and passing the process fuel gas through the water gas shift converter in effective contact with the high activity water gas shift catalyst system and converting a portion of the carbon monoxide in the process fuel gas into carbon dioxide and hydrogen by a water gas shift reaction with no methane formation at a temperature in a range of about 200° C. to about 425° C.Type: GrantFiled: March 18, 2004Date of Patent: July 3, 2007Assignee: General Motors CorporationInventors: Anca Faur-Ghenciu, Sailesh Mullapudi, Mark R. Feaviour, Nathan E. Trusty, Jessica G. Reinkingh
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Patent number: 7238334Abstract: A method of producing hypothiocyanite by combining a hypohalous acid and thiocyanate.Type: GrantFiled: July 14, 2005Date of Patent: July 3, 2007Assignee: The Board of Regents of the University of OklahomaInventor: Michael T. Ashby
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Patent number: 7238335Abstract: The invention concerns a process for the preparation of hydrogen peroxide by the anthraquinone cyclic process. The process includes a regeneration stage in which working solution is regenerated by being brought into contact with an aqueous solution containing an alkyl anthrahydroquinone and/or an alkyl tetrahydroanthrahydroquinone in deprotonated form. The working solution regenerated in the regeneration stage is returned to the cyclic process.Type: GrantFiled: August 6, 2004Date of Patent: July 3, 2007Assignee: Degussa AGInventors: Gustaaf Goor, Eugen Staab, Jürgen Glenneberg
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Patent number: 7238336Abstract: A method of forming ?-alane. The method includes reacting aluminum trichloride and an alkali metal hydride to form an alane-ether complex solution. An aqueous diethyl ether solution is optionally added to the alane-ether complex solution to form a partially hydrolyzed ether/alane-ether complex solution. A solution of a first crystallization additive is added to the alane-ether complex solution or to the aqueous ether/alane-ether complex solution to form a crystallization solution. The first crystallization additive is selected from the group consisting of polystyrene, polybutadiene, polystyrene-co-polybutadiene, polyisoprene, poly-alpha-methylstyrene, polystyrene-co-polyindene, poly-alpha-pinene, and mixtures thereof. Optionally, a second crystallization additive is added to the crystallization solution.Type: GrantFiled: January 9, 2006Date of Patent: July 3, 2007Assignee: Alliant Techsystems Inc.Inventors: Gary K. Lund, Jami M. Hanks, Harold E Johnston
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Patent number: 7238337Abstract: An all-silica zeolite having the IFR framework topology can be directly synthesized by preparing a reaction mixture comprising (1) an active source of silicon oxide, (2) a structure directing agent comprising a N-benzyl-1,4-diazabicyclo[2.2.2] octane cation, (3) an active source of hydroxide and (4) water and maintaining the reaction mixture under conditions sufficient to form crystals of the zeolite.Type: GrantFiled: October 31, 2005Date of Patent: July 3, 2007Assignee: Chevron U.S.A. Inc.Inventor: Cong-Yan Chen
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Patent number: 7238338Abstract: Disclosed are methods for manufacturing radiohalogen-labeled steroids, nucleosides, nucleotides and proteins, for example, pyrimidines and proteins. Methods according to the example embodiments specific to pyrimidines includes dissolving a halogenated pyrimidine to obtain an initial solution, adding bis(tributyltin) and triphenylphosphine palladium to produce a catalyzed solution, heating the catalyzed solution under conditions sufficient to induce a reaction that produces an intermediate solution including a stannylated pyrimidine compound, removing substantially all of the first solvent from the intermediate solution to obtain an intermediate composition, purifying the resulting solution to obtain a purified composition including a stannylated pyrimidine, reacting the stannylated pyrimidine compound with a radiohalogen in a buffered reaction mixture to produce the radiohalogenated pyrimidine, adding an antioxidant and extracting the radiohalogenated pyrimidine from the reaction mixture.Type: GrantFiled: June 20, 2002Date of Patent: July 3, 2007Assignee: TriumfInventor: Jianming Lu
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Patent number: 7238339Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.Type: GrantFiled: August 4, 2003Date of Patent: July 3, 2007Assignee: DRAXIS Specialty Pharmaceuticals Inc.Inventor: Jean-Marc DuFour
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Patent number: 7238340Abstract: Therapeutically active thiazole derivatives of formula (I) wherein R1-R2, X and X? as are defined in the specification, processes for the preparation thereof, the use thereof in therapy, particularly in the treatment or prophylaxis of disorders characterised by overexpression of transforming growth factor • (TGF-•), and pharmaceutical compositions for use in such therapy.Type: GrantFiled: June 3, 1994Date of Patent: July 3, 2007Assignee: CIS bio internationalInventors: William McBride, Richard T. Dean
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Patent number: 7238341Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.Type: GrantFiled: February 25, 2004Date of Patent: July 3, 2007Assignee: Epix Pharmaceuticals, Inc.Inventors: Zhaoda Zhang, John C. Amedio, Peter D. Caravan, Stephane Dumas, Andrew Kolodziej, Thomas J. McMurry
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Patent number: 7238342Abstract: Methods and solutions are provided for removal of the smear layer on prepared tooth and bone surfaces, especially in endodontic environments.Type: GrantFiled: January 21, 2003Date of Patent: July 3, 2007Assignee: Dentsply InternationalInventors: Mahmoud Torabinejad, William B. Johnson
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Patent number: 7238343Abstract: Hair removal, especially from armpits damages skin, for example by irritating it, and this can be exacerbated by the application of antiperspirants to control body odour generation. In the present invention, the deleterious effects of hair removal, eg shaving, and antiperspirancy can be ameliorated by employing antiperspirant compositions containing a natural oil and glycerol to a combined concentration of from 1.5 to 15% by weight and in a weight ratio of from 4:1 to 1:4.Type: GrantFiled: December 11, 2003Date of Patent: July 3, 2007Assignee: Unilever Home & Personal Care USA division of Conopco, Inc.Inventors: Robert Stanley Lee, Allan Watkinson
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Patent number: 7238344Abstract: The present invention provides new interferon ? conjugates, methods of preparing such conjugates and the use of such conjugates in therapy, in particular for the treatment of multiple sclerosis.Type: GrantFiled: December 19, 2002Date of Patent: July 3, 2007Assignee: Maxygen, Inc.Inventors: Anders Hjelholt Pedersen, Kim Vilbour Andersen, Claus Bornaes, Poul Baad Rasmussen
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Patent number: 7238345Abstract: Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.Type: GrantFiled: June 5, 1995Date of Patent: July 3, 2007Assignee: Wyeth Holdings CorporationInventors: Robert C. Seid, Jr., Peter R. Paradiso, Jan T. Poolman, Peter Hoogerhout, Emmanuel J. H. J. Wiertz, Peter van der Ley, John Edward Heckels, Ian Nicholas Clarke
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Patent number: 7238346Abstract: The invention relates to adenoviral vectors. More particularly, this invention relates to recombinant high capacity adenoviral vectors which can be employed in the treatment of hemophilia A, as well as methods and process for their creation and use.Type: GrantFiled: July 8, 2002Date of Patent: July 3, 2007Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZWInventors: Thierry Vandendriessche, Marinee Chuah, Stefan Kochanek, Gudrun Schiedner
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Patent number: 7238347Abstract: The present invention discloses the use of a mutant Leishmania as a suicidal vaccine wherein the mutant Leishmania is responsive to external signals to become porphyric and commit suicidal cytolysis. The mutant can be selected from natural Leishmania species or constructed by genetic engineering.Type: GrantFiled: March 28, 2005Date of Patent: July 3, 2007Assignee: Rosalind Franklin University of Medicine and ScienceInventors: Kwang-Poo Chang, Bala Krishna Kolli, Shigeru Sassa
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Patent number: 7238348Abstract: Methods are disclosed for using red rice fermentation products for the treatment or prevention of osteoporosis and abnormal bone mass conditions. Particular Monascus strains yield fermentation products with the desired biological activities.Type: GrantFiled: January 28, 2003Date of Patent: July 3, 2007Assignee: Beijing Peking University WBL Corporation Ltd.Inventors: Zhang Mao Liang, Duan Zhen Wen, Peng Chi Xiu, Zhou Yu-Fang, Guo Shuren, He Dalin
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Patent number: 7238349Abstract: The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.Type: GrantFiled: September 27, 2000Date of Patent: July 3, 2007Assignees: SmithKline Beecham Biologicals, s.a., Saechsisches Serumwerk DresdenInventors: Erik D'Hondt, Norbert Hehme
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Patent number: 7238350Abstract: The present invention relates to isolated polypeptides having phytase activity, the corresponding cloned DNA sequences, a process for preparing such polypeptides, and the use thereof for a number of industrial applications. In particular, the invention relates to phytases derived from the phyllum Basidiomycota, phytases of certain consensus sequences and fungal 6-phytases.Type: GrantFiled: November 30, 2001Date of Patent: July 3, 2007Assignee: Norozymes A/SInventors: Soren Flensted Lassen, Lisbeth Bech, Anders Ohmann, Jens Breinholt, Claus Crone Fuglsang, Peter Rahbek Ostergaard
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Patent number: 7238351Abstract: The method of producing a microbial adherence inhibitor for administration to food animals to control the incidents of acidosis in food animals by preventing the adherence of colony-forming lactic acid producing bacteria in the rumen or intestinal tracts of the food animals. The method includes inoculating female birds in or about their egg laying age with a lactic acid producing bacteria that colonizes in the intestinal tract of the food animal to be treated. Allowing a period of time sufficient to permit the production in the birds of antibody to the lactic acid producing bacteria and harvesting the eggs laid by such birds. The antibody-containing contents of the eggs are then separated by the shells.Type: GrantFiled: September 8, 2003Date of Patent: July 3, 2007Inventors: Peter Nash, Bradley M. Mitteness