Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.

Abstract: Surgical apparatus includes bipolar electrodes and tissue-shearing blades configured to electrically contact tissue for electrocauterization thereof prior to shearing contact of the cutting blades with the tissue over wide angles of presentation of the tissue to the electrodes and blades. Extensions or protrusions disposed along facing edges of the electrodes separate the level at which tissue is electrically contacted by the electrodes from the level at which tissue is sheared by the cutting blades.

Abstract: An anterior spinal fixation system comprises a plurality of mounting constructs to hold one or more spinal rods or spinal plate-type braces. Each mounting construct includes a bottom plate and a top plate assembly. The bottom plate is attached to the vertebral body with a plurality of anchors, one or more of which may be polyaxial. In one embodiment, the top plate assembly engages the bottom plate through a quick-connect feature that provides simple and secure locking as well as tactile feedback. When the top plate assembly is engaged with the bottom plate, it compresses the rods or braces against the head of the screws, locking the angle of any polyaxial bone screws. In another embodiment, the top plate assembly threadably engages the bottom plate. For additional strength and rigidity, cross-connectors may be used between each pair of mounting constructs when two or more spinal rods are used.

Abstract: A fixation device for fixation and/or fusion of the bones and joints of the mid-foot includes a plate having a plurality of screw holes for attachment of the plate around the perimeter of the fusion site. Four screw holes are positioned at the corners of the plate and two screw holes are located at the opposite sides and mid-length of the plate. Four additional screw holes are defined at the interior of the plate to increase the number of points of attachment of the plate to the bones of the mid-foot or to increase the ability to stabilize multiple bone segments in the case of a difficult mid-foot fracture. The plate includes a plurality of cut-outs defined between or interior of the screw holes.

Abstract: An intervertebral connection system having a fabric-based conformable ligament is disclosed herein.

Abstract: A method and apparatus for resectioning a patella without everting it includes a resection guide which grips the patella with gripping members, one of which can also function as an alignment guide for a surgeon using a saw for the resectioning. A sizing/alignment guide engageable with the resection guide is provided for aligning drills and/or reamers used in resectioning. Under one embodiment, a pair of reamers are provided for reaming the patella in two reaming operations.

Abstract: Methods and apparatus for knee arthroplasty utilize components including an alignment device, a single medially or laterally located guidance device, and a cutting device for use in preparing the bones of a knee joint to receive knee arthroplasty implants. The alignment device is used to locate and orient the guidance device adjacent the medial or lateral side of a long bone of a knee joint. The cutting device is engaged with the guidance device and plunged across the end of the long bone to create a resected surface with respect to which a knee arthroplasty implant will be fixed. In one embodiment, the cutting tool guidance device extends less than about half way across the end of a long bone of a knee joint.

Abstract: A tibial alignment guide assembly for positioning a resection guide, the assembly including a main shaft having a proximal end and a distal end. The assembly also includes an anchor arm having an engaging end and a connection end. The connection end is preferably attached to the proximal end of the main shaft and the engaging end preferably has at least one anchor pin extending outwardly therefrom. The at least one anchor pin is adapted to anchor the tibial alignment guide assembly to a tibia plateau in order that the resection guide may be correctly aligned to the tibia. The assembly further includes a lever including an actuation end and a handle. The lever is pivotally connected to the anchor arm, whereby movement of the lever while the actuation end bears against the tibia plateau surface, causes at least a partial extraction of the at least one anchor pin from the tibia plateau.

Abstract: A catheter apparatus is provided for isolation of the left atrial appendage (LAA) having a catheter shaft, a probe disposed within the catheter shaft, and a control mechanism coupled to both the catheter shaft and the probe. The catheter shaft includes a main body with a distal tip section. The tip section can be deflected from the shaft's central axis in a controlled manner. The probe can be extended outward from the catheter shaft and has a distal end that is brought into contact with the LAA. The control mechanism controls the catheter shaft's rotational and longitudinal movement, the tip section's degree of deflection, and the probe's axial movement with respect to the catheter shaft. Preferably, the distal end is able to form a pre-stressed loop selected to have a size allowing it to substantially encircle the LAA's base. A method for epicardial isolation of the LAA is also provided.

Abstract: A system for closing an opening in tissue may include an end effector that holds a staple, where the staple is plastically deformed to a splayed configuration for engaging tissue, then plastically deformed to a closed condition for closing the opening. The system may include one or more butterfly members configured to register the opening to the end effector.

Abstract: An endoscopic treatment device is used with an endoscope. This treatment device includes a transmission member with a flexible structure having a distal end portion to be inserted into a body and can be operated outside the body, a push rod coupled to the distal end portion, and first and second connecting members rotatably coupled to the push rod. The treatment device further includes first and second arm members rotatably coupled to the distal end portion of the connecting member, a holding member rotatably holding the respective arm at a predetermined interval therebetween, and first and second actuating members integrally formed with the arm members and can open/close when the transmission member actuates the first and second connecting members and the first and second arm members through the push rod. This device also includes a needle mounted on at least one of the first and second actuating members.

Abstract: Intralumenal material removal systems are provided using an advanceable and rotatable cutter assembly designed for differential cutting. The intralumenal material removal system includes a cutter assembly positionable in the body cavity of a mammalian subject. One embodiment of the cutter assembly includes a cutter with blades that are designed and arranged to form an acute blade angle of attack with the matter-to-be-removed. The cutter assembly is axially advanceable by translating the drive shaft and rotatable by rotating the drive shaft. The occlusive material is scraped by the cutter assembly and may be aspirated to remove the material from the body cavity. The cutter assembly may provide aspiration ports positioned between facing surfaces of the blades.

Abstract: Laparoscopic instruments and trocars are provided for performing laparoscopic procedures entirely through the umbilicus. A generally C-shaped trocar provides increased work space between the hands of the surgeon as well as S-shaped laparoscopic instruments placed through the trocar when laparoscopic instrument—trocar units are placed through the umbilicus. In order to facilitate retraction of intra-abdominal structures during a laparoscopic procedure, an angulated needle and thread with either one-or two sharp ends is provided. Alternatively, an inflatable unit having at least one generally C-shaped trocar incorporated within the unit's walls can be placed through the umbilicus following a single incision. Generally S-shaped laparoscopic instruments may be placed through the generally C-shaped trocars to facilitate access to intra-abdominal structures.

Abstract: A surgical instrument and method are disclosed for enhancing the overall performance of arterial occludes, by allowing the repetitive obstruction of blood flow to a targeted organ or tissue (e.g., heart muscle, brain, kidney, gastrointestinal tissue, leg muscles, arm muscles, other skeletal muscles, or tumors), while reducing the potential for side effects such as gangrene or infarction and for post-implantation movement of the occlude during ischemia. The micro-pneumatic snare allows the repeated occlusion (i.e., the iterated obstruction or closure of a passageway or vessel) of targeted vessels to deprive a selected organ or tissue of blood and oxygen profusion, while the patient may, in general, remain conscious. The micro-pneumatic snare also allows for the stimulation of functional response adjustments in targeted tissues and organs, such as angiogenesis and collateral vessel growth in response to repetitive per fusion obstruction.

Abstract: A self-expanding cage for use in conjunction with an embolic filtering device includes a circumferential member adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. A proximal strut and distal strut are attached to the circumferential member to form the cage. A plurality of proximal and distal struts may be attached the circumferential member. Additionally, a second circumferential member can be attached to the first circumferential member. Each circumferential member can be connected by a single or a plurality of connecting struts. One embodiment of the cage utilizes a single wire to form to the cage. A delivery system attached to the single wire cage moves the cage and its associated filter element between the expanded and unexpanded positions through relative movement of the distal delivery system.

Abstract: A device for removing blood clots and methods of making and using the same. The clot pulling device may include a shaft and one or more strut members that each may include a loop region. The proximal ends of the strut members may be attached to the shaft and the distal ends of the strut members may be coupled to the shaft.

Abstract: Devices and methods for filtering blood. The devices generally comprise a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, and a means to actuate the structure. The methods generally include the steps of introducing a mesh into a blood vessel to entrap embolic material, and removing the mesh and the entrapped foreign matter from the blood vessel.

Abstract: A mechanical coupling device is provided for temporarily interconnecting a gem or a crystal to be used for acupressure treatment to a vibration generating device. Alternatively a mechanical coupling device is provided for temporarily interconnecting the handle of an acupuncture needle to a gem or a crystal. The mechanical coupling device can be a helical or spiral, metal wire, a cylindrical linkage, a conical linkage or a clamp connecting the acutreatment device to the other element. The method employed is to apply the acutreatment devices to acupoints of a patient with the above devices including the combination of a gem or a crystal interconnected to an acupuncture needle or a vibration generating device interconnected to an acupressure gem or crystal.

Abstract: A coupling system is disposed at the distal end of an interventional delivery system for coupling to an implant. The coupling device has a first and second prong connected at one end. The other end of the prongs open or close to release or trap an object, e.g., a bead tethered from an implant. A slot at the distal end of the coupling device allows extra degrees of flexibility for the coupling device.

Abstract: The present disclosure is directed to a medical device or article that reduces the ability of the Keith needle to unintentionally fall out of the barrel, improves the ability of the Keith needle to track on axis, or both. In one aspect, the disclosure is directed toward a medical device suitable for use in implant surgery. The medical device includes a Furlow insertion tool with a barrel having a bore. The Furlow tool further includes an obturator adapted for slidable insertion into the bore. The medical device further includes a Keith needle adapted for slidable insertion into the bore. The Keith needle is adapted to yieldably fit against at least one of the barrel and the obturator when the Keith needle is disposed within the bore. In another aspect, the present disclosure is directed toward a Keith needle adapted for use with a Furlow insertion tool. The Furlow insertion tool including a barrel and an obturator.

Abstract: The present invention relates generally to the treatment of SCI by stimulating axon regeneration within the central nerve system. One aspect of the present invention provides methods of treating SCI with low power laser irradiation (LPLI). Another aspect of the present invention provides methods of treating SCI by modulating a gene activity to stimulate axon regeneration. In this regard, the present invention also provides compositions that modulate genes expression relating to the neuron-regeneration after SCI. Another aspect of the present invention provides methods for evaluating the effectiveness of a treatment for SCI.

Abstract: A device and method for treating pathological narrowing of fluid-carrying conduits of the human body (such as blood vessels) in an area of a bifurcation is disclosed. In particular, a stent delivery system configured to carry one or more of a pair of dissimilar stents. At least one of the stents is particularly suited for treating a widened portion of a blood vessel immediately proximal to a bifurcation. The stent delivery system can also include a handpiece adapted to selectively deliver the stents.

Abstract: Apparatus and method are provided for treatment of a bifurcation of a body lumen. The apparatus includes an elongated catheter body having a proximal end and a distal end. A balloon is associated with the distal end of the balloon catheter. The balloon includes a main vessel balloon for treating a main vessel of the bifurcation, and a branch vessel balloon for treating a branch vessel of the bifurcation. The branch vessel balloon includes an accordion configuration capable of being expanded from an unexpanded collapsed accordion configuration to an expanded accordion configuration extending into the branch vessel.

Abstract: A vascular occlusion device deployment system for deploying an occlusion device at a preselected site within the vasculature of a patient. The deployment system includes a pusher which has a constrictor located at the distal end portion of the pusher. The constrictor has a channel which receives a portion of the occlusion device. The constrictor has a proximal end portion and a distal end portion wherein the proximal end portion can be moved relative to the distal end portion to reduce the size of the channel. When the channel size is reduced, the constrictor grasps the portion of the occlusion device located within the channel. When it is desired to deploy the coil, the constrictor is moved in the opposite direction to increase the size of the channel and release the coil's grasp of the occlusion device.

Abstract: A medical device includes a pattern of electrically conductive material. The pattern of electrically conductive material has an anti-antenna geometrical shape such that the anti-antenna geometrical shape substantially prevents the medical device from creating an imaging artifact and/or substantially allows imaging of a volume within the medical device. The pattern may be formed by multiple “figure-8” shaped electrical conductors, multiple “figure-8” emulating electrical conductors, multiple sine-wave-like shaped electrical conductors, multiple zig-zag patterned electrical conductors, by multiple electrical conductors, each having sequential conductive loops, and/or a single conductor weaved into a loop mesh. The electrically conductive material may be titanium, tantalum, nitinol, stainless steel, and/or NbZr.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, an endoprosthesis includes a first portion having a first width, and a second portion having a second width different than the first width, wherein the first and second portions have different grain sizes.

Abstract: An endoluminal device including a prosthesis and at least one indicator member affixed to the prosthesis that can be remotely monitored to indicate a change in pressure or morphology of the prosthesis. The indicator member may be an optical fiber, a strain gauge, or a first material having a first magnetic resonance imaging (MRI) susceptibility value that contrasts with a second MRI susceptibility value of a second material that comprises one or more remaining members of the prosthesis. A prosthesis monitoring system includes an endoluminal device as well as a subcutaneous electronics package and external electronics. Methods of detecting endoleaks or changes in morphology involve implanting an endoluminal device with the indicator and detecting information from the indicator.

Abstract: An endoprosthesis for repairing and treating abdominal aortic aneurysms. The endoprosthesis features an anchoring and sealing component and low profile bifurcated legs. A biocompatible graft material is secured to at least the bifurcated legs in order to provide two endoleg fluid flow lumens or conduits. The bifurcated legs have staggered stent elements that nest to contribute to the low profile nature of the device and additional longitudinal struts between pair of the staggered stent elements to increase the longitudinal stiffness of the bifurcated legs while maintaining the patency of the lumen created thereby.

Abstract: A stent for use at an implant site in a vessel having recesses containing one or more active agents. The stent is a tubular body having a plurality of sinusoidal shaped annular elements and connection elements. The recesses are formed so as to leave substantially unaltered the bending moments of these elements. The recesses may be continuous or discontinuous and may be distributed uniformly or nonuniformly.

Abstract: The present invention relates to an expandable spinal stabilization device that may be inserted into the space between two vertebrae, normally occupied by a disc, in order to stabilize the spine during and after spinal fusion procedures. The invention also relates to a method for using the device. The device generally includes a stack of plates connected by a connecting rod in a manner that allows the plates to adopt a helical configuration about the connecting rod when the plates are rotated about the longitudinal axis of the rod.

Abstract: An acetabular component comprises a thin-walled, partial spherical body having an inner surface defining an articular surface and having angled recesses along an outer surface of the body for releasable engagement with an insertion and extraction tool. An insertion and extraction tool comprises a spring-loaded locking member movable from an extended position to a retracted position in response to relative sliding movement of an outer sleeve and inner shaft of the tool effected via an actuating force at a proximal end of the tool. The tool comprises engagement members insertable in the recesses when the locking member is retracted and, upon release of the actuating force, the locking member automatically returns to the extended position causing fingers of the locking members to enter the recesses and lock the acetabular cup to the tool.

Abstract: A lip implant having first and second regions is described. The lip implant includes a first region formed of a liquid, solid, or a gas and a second region formed of a solid material. Also described is a lip implant having an elongated cross-section. A method for insertion of the implant is also described along with the instrumentation facilitating its insertion.

Abstract: An immediate postoperative prosthesis including: a base adapted to receive a distal prosthetic component, the base comprising a substantially circular pan having a raised wall extending proximally about its periphery; a plurality of flexible straps mounted to and extending proximally from the interior face of the raised wall of the circular pan, the flexible straps adapted to interface with a postoperative residual limb; and wrap materials wrapped around and substantially solidified about the flexible straps. The invention also includes a process for postoperative fitting of a prosthetic component to a residual limb of a prosthetic recipient.

Abstract: Tear and fatique resistant SEEPS gels useful for making liners for orthotics and prosthetic uses.

Abstract: A selector valve capable of maintaining a closed position for a while even if an operating force to a valve element (80) is eliminated when the selector valve (10) is switched from a closed position (braking state) to an open position. The valve element (80) of the selector valve (10) receives an operating force from the outside and a returning force in the opposite direction of the operating force by a valve spring (90). Accordingly, the valve element (80) opens and closes the valve by making the first end (801) of the valve element (80) seat on/unseat from a valve seat (48) on the housing (20) side according to the presence or absence of the operating force. A first port (31) and a second port (32) on both sides of the valve seat (48) are connected or cut off from each other by the opening and closing. The valve element (80) is formed in a stepped structure, and receives a force based on a difference in pressure receiving area by the stepped structure which results from the pressure of hydraulic fluid.

Abstract: A method for manufacturing an emulsifier package is disclosed. The method comprises blending a flow of fuel soluble product, a flow of stabilizer, and a flow of water in a mixing vessel to form a mixture. Mixing the mixture in the mixing vessel and recirculating the mixture through the mixing vessel. Lastly, shearing the mixture with a shearing device at a rate of about 27,500 shears per second to about 87,500 shears per second. A method for manufacturing an aqueous fuel emulsion is also disclosed.

Abstract: A hydrogen generator includes a housing, a solid hydrogen source disposed within the housing, and an inlet configured to guide a fluid to contact the solid hydrogen source. The inlet can contact a wicking region. The wicking region can include a wicking material that has an affinity for the fluid. The wieking material can include a hydrophilic material. The housing can include a hydrogen gas outlet. The hydrogen generator can include an end cap at one end of the housing including the inlet and the hydrogen gas outlet. The hydrogen gas outlet can include a gas permeable membrane. The inlet can be fluidly connected to a fluid control system configured to control fluid flow rate to the solid hydrogen source. The generator can be portable.

Abstract: A reforming apparatus that generates hydrogen from fuel includes a plurality of reactors each having an internal space and reacting fuel in the internal space, a heat insulating package that contains the plurality of reactors, and a heat insulator that supports the plurality of reactors to be separated from an inner wall of the heat insulating package.

Abstract: An additive impregnated abrasive article and method for fabricating the same is provided. The method includes providing an abrasive article having a pore structure, dissolving an additive in a supercritical fluid, and exposing the abrasive article to the additive-laden supercritical fluid, so that the fluid disperses through the pore structure. The supercritical fluid is then brought to below its critical point for a period of time sufficient to dissociate the additive from the fluid, so that the additive is deposited within the pore structure of the abrasive article.

Abstract: A coated abrasive article has a backing treatment preparable by at least partially polymerizing an isotropic backing treatment precursor comprising polyepoxide, polyfunctional urethane (meth)acrylate, non-urethane polyfunctional (meth)acrylate, acidic free-radically polymerizable monomer, dicyandiamide, photoinitiator. Methods of making and using the same.

Abstract: A curable composition comprises epoxy resin preparable by reaction of epichlorohydrin with at least one of bisphenol A or bisphenol F, polyfunctional urethane(meth)acrylate, dicyandiamide and photoinitiator. The curable composition is useful for preparing treated backings and coated abrasive articles.

Abstract: Methods of separating fluids using capillary forces and/or improved conditions for are disclosed. The improved methods may include control of the ratio of gas and liquid Reynolds numbers relative to the Suratman number. Also disclosed are wick-containing, laminated devices that are capable of separating fluids.

Abstract: A filter tube frame for use with a filter bag house. The filter tube frame includes an end cap having a pivotable handle attached thereto to facilitate removal of the tube frame from the bag house. The handle includes a lever surface adapted to engage a tube sheet surface, thus, during use, providing a force to urge the end cap away from the tube sheet and unseat the filter tube frame from the tube sheet.

Abstract: A breather valve device for a container for an electronic control unit, includes a support structure including, a substantially planar wall having first and second surfaces intended to face outwardly and inwardly of the container respectively, and in which is formed an aperture, and a projecting, essentially cylindrical, tubular wall extending from the first surface of the planar wall, substantially around the aperture; an interceptor element having a smaller cross section than the passage cross section of the tubular wall and of the aperture; the interceptor element being disposed inside an axially intermediate portion of the tubular wall, spaced radially from the latter so as to define, with respect to the tubular wall, a narrow annular gap; the interceptor element being connected to the support structure by at least one connector formation. The support structure, the interceptor element and the connector formation are integrally formed in one piece of molded plastics material.

Abstract: A pipe trap comprising a body, a disc filter, a pipe and a plurality of mesh filter suitable for filtering gases is provided. The pipe trap body has a gas inlet and a gas outlet. The disc filter and the mesh filters are enclosed inside the pipe trap body. One end of the pipe connects with the disc filter and the other end of the pipe connects with the gas outlet. The mesh filters are enclosed inside the pipe. Using a multi-stage filtering method, liquid matter separates out first and then gaseous particles are filtered according to the particle size so that the pipe trap has a high filtering efficiency.

Abstract: Converting machines give rise to polluted air which must be removed with the aid of fans and filters. The invention aims at removal of the polluted air in such a way that the servicing interval is greatly extended by the use of a filter unit having a number of part-filters arranged one after the other and formed of pleated fiber mats, the various mats having different filtering properties.

Abstract: A filter assembly for removing material that is entrained in a gas stream. The filter assembly comprises a filter element comprising a wall of a filtration medium which defines a hollow space, for a gas stream to flow from the space through the wall to be filtered. The wall includes a filtration layer, and a drainage layer located outside the filtration layer in which liquid separated from the gas stream can collect. The filter element comprises first and second end caps at opposite ends of the wall, the first end cap including an inlet for a gas stream to be supplied to the space within the wall. The filter assembly further comprises a housing in which the filter element can be received when in use. The housing has an inlet port for a gas stream to flow into the housing which communicates with the inlet in the first end cap, and an outlet port through which gas which has passed through the filtration medium can leave the housing.

Abstract: This invention relates to a filter assembly for removing material that is entrained in a gas stream. The filter assembly comprises a housing which comprises head and body parts, with an inlet port in the head part for a gas stream to flow into the housing, the head and body parts having formations which enable them to be connected to one another and separated by relative rotation. The filter assembly further comprises a filter element which can be fitted within the housing. The filter element comprises a wall of a filtration medium which defines a hollow space for a gas stream to flow from the space through the wall to be filtered, and an end cap with an inlet which can be sealed to the inlet port in the head part of the housing to provide a flow path for a gas stream to be supplied from the inlet port in the housing to the said space.

Abstract: Composite particles of a metal particle within a crosslinked, cored dendrimer are described. Additionally, methods of making the composite particles and compositions that contain the composite particles are described.

Abstract: A process for the production of extra fine spherical metal powders by chemical vapor deposition and dissolution techniques, including metal carbonyls, wherein the metal containing process gas is propelled upwardly through a heated reactor. By employing an upward gas flow as opposed to the conventional downward gas flow, a closer approximation of theoretical plug-flow velocity profiles are achieved thusly resulting in a desirably narrower size particle distribution obviating or reducing the need for subsequent classification techniques.