Abstract: An antibacterial alloy coating composition is applied to a surface of a device. The composition comprises an antibacterial material and an alloy. The alloy consists of more than four metallic elements and at least one non-metallic element. The antibacterial material is, for example, copper, silver, or a combination thereof, and the atomic percentage content thereof is 1.7% to 26.8% of the total content. These metallic elements are selected from the group consisting of iron, cobalt, chromium, nickel, aluminum, vanadium, and titanium. The non-metallic element is selected from the group consisting of boron, oxygen, and nitrogen.

Abstract: A method of preventing or treating conditions of peri-menopausal, menopausal, or post-menopausal skin comprising applying to the skin tissue, a safe and effective amount of a composition comprising between 1.0% to 3% by weight of S-palmitoyl glutathione and a dermatologically acceptable carrier.

Abstract: Inhibitors of poly(ADP-ribose)polymerase having a structure of Formula (I), ways to make them and methods of treating patients using them are disclosed.

Abstract: The present invention provides Compound 1, solid forms thereof, compositions thereof, as Aurora kinase inhibitor for use as an oncology agent. The present invention also provides synthetic methods of preparing Compound 1 and intermediates thereto.

Abstract: There is provided methods and uses for promoting cell death, when combined with chemotherapeutic agents, in an abnormally proliferating cell, and for treating a proliferative disorder in a subject, which methods and uses involve contacting a cell with, or administering to a subject, an agent that modulates glycogen synthase kinase-3? activity to a cell that is being treated with a chemotherapeutic agent.

Abstract: The field of colonic diagnostic and surgical procedures is hampered by the lack of optimal means available to cleanse the colon. A compromise between convenient, distasteful, solid or low volume, hyperosmotic solutions which cause considerable fluid and electrolyte imbalances in patients and large volume, difficult to consume, iso-osmotic solutions has had to be made heretofore. This invention describes a low volume, hyper-osmotic solution consisting of sulfate salts with and with out polyethylene glycol, and further comprising a sweetener and/or flavoring. Unlike prior art, this composition is useful for the cleansing of the bowel and, in lower volumes, as a laxative, without producing clinically significant changes in bodily function.

Abstract: The present invention relates to a method of treating sepsis, systemic inflammatory response syndrome (SIRS), and/or septic shock in a patient. The method comprises administering (a) a pharmaceutical composition comprising a selenium-containing active substance, (b) a pharmaceutical composition comprising a corticoid-containing active substance, and (c) a pharmaceutical composition comprising insulin.

Abstract: Disclosed herein are surgical adjuvant compositions for ameliorating tissue and cellular necrosis and/or apoptosis. In addition, surgical methods are described which include the use of the adjuvant of the composition to reduce tissue and cellular necrosis and/or apoptosis.

Abstract: The present invention is directed to a method of determining the prospects for survival of a melanoma patient. This method involves providing a biological sample from a patient diagnosed with melanoma, determining the level of an indicator of Wnt/?-catenin activation in the sample, comparing the level of the indicator of Wnt/?-catenin activation in the sample against a standard level of the indicator of Wnt/?-catenin activation correlated to survival of melanoma, and determining a patient's prospects for survival of melanoma based on the comparison. The present invention also relates to a method of improving survival of melanoma patients, decreasing metastases in melanoma patients, decreasing proliferation of cancer cells in melanoma patients, decreasing melanoma recurrence in melanoma patients, and/or decreasing tumor size in melanoma patients. This involves selecting melanoma patients and subsequently determining and monitoring therapy based on their level of Wnt/?-catenin activation.

Abstract: The present invention provides a composition comprising stearidonic acid (or an ester thereof) derived for example from Echium oil, and an additional lipid (derived for example from calendula oil) which enhances the pro-collagen effects of stearidonic acid. The composition is useful in reducing visible signs of aging of human or animal skin or a method of wound healing.

Abstract: Noni juice and a protein-free, alcohol precipitate of Noni juice inhibited angiogenesis in in vitro human angiogenesis models. When growth medium contained Noni juice at least over the range from about 2.5% to about 33% (by volume), angiogenesis was blocked. Moreover, Noni juice and an ethanol precipitate were able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Noni juice was effective in inhibiting the growth of angiogenic vessels from breast cancer explants. It will also be effective in treating cancers and non-cancerous diseases whose response includes an increase in angiogenesis, e.g., retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, and psoriasis. In an initial experiment, Noni juice was effective in treating lesions associated with psoriasis. The primary antiangiogenic component is believed to be a carbohydrate with a molecular weight less than about 6000 Daltons.

Abstract: Compositional formulations are provided that comprise at least one tocotrienol or a derivative thereof, in combination with compounds derived from plant extracts. The compositions can be provided in a functionally acceptable carrier, or separately in a combined regimen. In some examples, the compositions can be effective for reducing, preventing or treating medical conditions including, for example, benign tissue growths, pre-cancerous lesions, cancer, inflammations, viral infections, bacterial infections, fungal infections, parasitic infections, impaired bodily function, or cell and tissue damage due to trauma, cell and/or tissue injury from stroke events, cell and/or tissue damage from ischemic events. The mechanism of action for cancer prevention and therapy includes telomerase and/or angiogenesis inhibition.

Abstract: The present invention relates to the anticancer composition containing an effective amount of herbal extract, and more particularly to the anticancer composition containing an effective amount of extract of Salviae Miltiorrhizae Radix, Chrysanthemum indicum, Acanthopanax senticosus, Cinnamomum cassia Blume, Eucommia ulmoides Oliv., Glycyrrhiza uralensis Fisch, Pueraria thunbergiana Benth, Crataegus pinnatifida Bunge, Cassia tora, Carthamus tinctorius L., Paeonia lactiflora Pall, and Angelica gigas Nakai. The anticancer composition containing an effective amount of herbal extract has advantage of minimal or few side effects and cytotoxicity as compared to many existing anticancer drugs having cytotoxicity and side effects.

Abstract: A stabilized formulation for skin care, wound care and/or other tissue healing applications and methods for making the same is described. The stabilized formulation stabilizes omega-3 polyunsaturated fatty acids and is constituted of the omega-3 polyunsaturated fatty acids in combination with tocopherol (Vitamin E), ascorbic acid (Vitamin C), herb extract, and a fat-soluble antioxidant. Methods for making and using the stabilized formulation are also described.

Abstract: A composition for foods or medicaments, containing a fermentation product or an enzyme-treated product that is either obtained by fermenting or treating with an enzyme at least one type of component selected from the husks, pellicles and astringent skin of Coix seeds.

Abstract: Compositions for the treatment and/or prevention of cancer are described. Preferably the composition comprises a therapeutically effective amount of tea tree oil from Melaleuca alternifolia, together with a pharmaceutically or therapeutically acceptable carrier and/or diluent. Methods for the treatment and/or prevention of cancer are also described. Preferably the method is used for the treatment and prevention of skin cancer. More preferably, the method is used for the treatment and prevention of basal cell carcinoma, squamous cell carcinoma and/or melanoma.

Abstract: A method for anti-oxidation, inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, and/or promoting the expression of collagen in a mammal is provided, and the method comprises administrating an effective amount of an Ixora parviflora leaf extract to the mammal.

Abstract: The present invention provides dietary supplement formulations that may be beneficial for developing and strengthening bones and joints. Also provided are methods of treating a bone disease, such as osteoporosis, and methods of strengthening bones and joints by administering the dietary supplements to a subject in need thereof.

Abstract: An exclusive manufacturing technique for extracting active interface saponin and organic substances from soapberry; organic elements and oleic alcohol products from soapberry seeds through the process of fermentation and end products made therefrom, wherein the manufacturing process includes: 1. Pre-ferment soapberry fruit (1). 2. Processing said fruit (1) by a dialysis device (2). 3. Separating the soapberry flesh (12) and fiber (13) by a separation device (3). 4. Extracting soapberry dialytic liquid (A) through a grinding and compression device (4) and separating the fiber (13). 5. Eliminating bacteria inside the dialytic liquid (A) by a huge stewing device (5). 6. A second fermenting process by a vacuum device (6) and generating a soapberry syrup (D). Said method is healthy, toxin free and biologically safe, produce no wastage, zero carbon emissions, zero pollution, low energy production and is ecologically friendly. End products produced by said method are variables with excellent economic viability.

Abstract: Disclosed is a hot-runner system (101), including: an actuation plate (202) being movable; a valve stem (205) installed in the actuation plate (202), the valve stem (205) being movable responsive to movement of the actuation plate (202); and an electro-magnetic actuator (210) being coupled with the actuation plate (202), the electro-magnetic actuator (210) being configured to actuatably move the actuation plate (202).

Abstract: The invention relates to a method and device for the direct production of polyester granulate from a highly viscous polyester melt with a polymerisation degree of 132 to 165, as well as the granulates formed thereform. In the method, the highly viscous polyester melt is subjected to a pre-drying and drying/degassing after a hot cutting method. Hot cutting is implemented at water temperatures of 70° C. to 95° C. and with a liquid to solid ratio of 8 to 12:1.

Abstract: A device for manufacturing finely powdered spherical magnesium includes a gas compressor that compresses argon gas, a gas heating unit that heats the compressed argon gas, and a tundish that receives molten magnesium. The device further includes a reactor having a nozzle injection unit that injects heated argon gas into the reactor, a recovery unit that recovers magnesium powder produced in the reactor, and a first gas cooler that cools the argon gas passing through the recovery unit. The device further includes a filtering unit that filters the cooled argon gas, a buffer tank that receives the filtered argon gas, and a compression blower that adiabatically compresses the argon gas. The device further includes a second gas cooler that cools the compressed argon gas, an adiabatic expansion duct that adiabatically expands the cooled argon gas, supplies the expanded argon gas to the reactor, and cools the magnesium powder.

Abstract: A system for forming a spun bond nonwoven web from extruded polymer filaments includes a spinneret including a plurality of orifices to extrude a plurality of continuous polymeric filaments, and a pressure quench chamber including a top located proximate and below the spinneret and bounded peripherally by surfaces. The quench chamber includes an ingress opening extending substantially across the width of a top of the quench chamber to receive filaments from the spinneret and a chamber exit nozzle extending substantially across the width of a bottom of the quench chamber.

Abstract: A non-conforming golf ball has a plurality of dimples formed on the outer surface of the ball in a predetermined dimple pattern, the outer surface comprising one or more first areas which include a plurality of first dimples which together have a first dimple volume and at least one second area having a dimple volume less that the first dimple volume, the first and second areas being configured to establish a preferred spin axis. The second area may be a hand around the equator which has a lower dimple volume or no dimples, with the polar regions have a higher volume of dimples, creating a preferred spin axis through the poles.

Abstract: Disclosed herein is a machine for producing expanded-grain cakes. The machine includes a frame, a mold unit, a grain supply unit, a grain transfer unit, a mold pressure arm, a drive unit, an open cam, a control unit and a cover unit. A precise charge of cereal grain is metered at the grain supply unit and in synchronism with the mold open cycle, distributed evenly over the mold cavity. Then with the mold unit clamped closed, the charge is heated and, at the end of the baking cycle, a preform is produced with gases at high pressure entrained therewithin. Upon release from the mold, the preform expands to a grain cake of the desired size. The machine controls the thermal energy input, the cycle frequency, the size of the grain charge, and the ejection trajectory. Several interrupts are used to ensure conformance to the control parameters and to enhance operator safety.

Abstract: A method for curing a resin contained in a liner of an underground pipe or passageway by use of a mobile magnetron module. The module navigates the length of the passageway of pipe via air pressure which also keeps the liner inflated. A winch attached to the module regulates the rate at which the module traverses the passageway or pipe. As the module makes its way through the passageway or pipe, the magnetron emits microwaves which cures the resin. Additionally, a thermal imaging camera can be utilized in the module or trailing the module to monitor the status of the curing of the resin in its entirety.

Abstract: An injection mold has a lower mold half having a chamber at a top thereof. A holding plate has a top within the chamber formed with a plurality of holding slots. The holding slots extend frontward and rearward. A positioning plate is attached to a front surface of the holding plate, an upper portion of which within the chamber has a plurality of positioning holes at a front surface thereof. A fixing plate disposed rearward of the holding plate has a plurality of through holes at a top thereof. A plurality of first positioning rods is mounted to the installing holes, each of which defines a free end extending beyond the top of the fixing plate. A free end of each of a plurality of second positioning rods is capable of inserting into the positioning hole. An upper mold half is engaged with the lower mold half.

Abstract: The invention relates to a moulding and fitting system (100) for a first part and a second part, including: two guide rails (102); a carriage (108) translatably movable on the guide rail (102); a series of first recesses (120); a manoeuvring gear mounted on the carriage (108) and rotatably movable about an axis perpendicular to the movement direction of the carriages (108); a series of second recesses (116) mounted so as to be capable of moving between a lower position and an upper position; a rack adapted so as to move in parallel with the guide rail (102) and for meshing with the moving gears of the carriage (108); a locking device (106) adapted for alternately locking said carriage (108) with the rack and the guide rail; and an actuation device (04) for moving the rack.

Abstract: The invention concerns an apparatus (1) for producing a three-dimensional object layer by layer using a powdery material which can be solidified by irradiating it with an energy beam, such as electromagnetic radiation or an electron beam, said apparatus (1) comprising: a working area (3) onto which layers of powdery material are to be placed; a powder storage unit (11) comprising a base surface (13) for supporting a supply of powder (2); and a powder distribution member (6); wherein the base surface (13) extends along a side of the working area (3), wherein the distribution member (6) extends in a direction along the base surface (13) and said side of the working area (3) and is arranged to be moveable in a plane above, and substantially parallel to, the base surface (13) and the working area (3), and wherein the distribution member (6) is arranged to be moveable into a supply of powder (2) placed onto the base surface (13) such as to bring about a transfer of a portion of powder from a side of the distributi

Abstract: A means for modifying a building space for a device for manufacturing a three-dimensional object by layerwise solidification of a powdery building material at the locations corresponding to the object in the respective layers comprises one or several small supports (32) or one or several building space partitioning elements (20) on a building platform (2), thereby the device has one or several small building areas (22.1, 22.2, 22.3), in which the powdery material may be efficiently used and different powder materials may be processed.

Abstract: The invention concerns a mold for forming a single-use floss holder containing a length of dental floss having a wax composition applied thereto, the mold including a first part having a first cavity disposed therein, the first cavity defined by a bottom base surface and a peripheral sidewall, and including a base portion, first and second spaced-apart portions having proximal and distal sections and extending from the base portion, and a second part having a second cavity disposed therein, the second cavity defined by a bottom base surface and a peripheral sidewall, and including a base portion, first and second spaced-apart portions having proximal and distal sections and extending from the base portion and terminating in the distal section; and a groove having an aspect ratio of about 10:1 or greater and having first and second terminal sections and a mid-section, the groove extending an entire width of the second part, where the first and second terminal sections of the groove traverse and are coincident

Abstract: The invention relates to a mold clamping unit on a plastic injection molding machine, the unit having a clamping mechanism for opening and closing an injection mold, the mechanism having a servo motor as the drive motor (21). The drive motor drives at least one spindle drive (10) which has a spindle nut (12) and spindle which work together on a bearing position (14). A cooling system with cooling channels (25) is provided for removing heat from the clamping mechanism. A more efficient cooling of the spindle drive is achieved in that the cooling channels (25) penetrate the bearing position (14) of the spindle drive (10) and/or one of the cooling plates (23) assigned to the bearing position.

Abstract: A gate adapter for receiving a molten molding material and for the discharge thereof to a gate distributor block (9), wherein the gate adapter (7) has an inlet (10) for receiving the molten molding material, first and second outlets for the controlled discharge of the molten molding material and first and second closable connecting passages (18, 18?) which respectively connect an outlet to the inlet (10) and a gate distributor block for connection to a gate adapter as set forth in claim 20 wherein at least the gate distributor block (9) has two inlets for connection to outlets of the gate adapter (7) and at least two ingate passages (13) for connection to a mold cavity, wherein each ingate passage (13) is connected by way of distributor passages to at least one inlet of the gate distributor block (9).

Abstract: A transfer system for manufacturing molded parts of plastic by means of a plastic injection device is provided. The transfer system includes, a mold which can be opened via a mold separating surface; first and second injection stations formed in the mold; and a plurality of mold bars which are compatible with first and second injection stations. The pre-molded parts are manufactured in the first injection station and initially remain on the corresponding mold bar before being brought into the second injection station for molding a second workpiece section onto the pre-molded parts.

Abstract: The invention provides a mineral complex comprising about 40 wt. % to about 60 wt. % SiO2, about 6 wt. % to about 16 wt. % Fe2O3, about 4 wt. % to about 12 wt. %. CaO, and about 2 wt. % to about 8 wt. % MgO. The invention also provides animal feeds comprising the mineral complex. Methods for increasing the feed efficiency and weight gain in an animal by administering the mineral complex or an animal feed comprising the mineral complex also are provided.

Abstract: The invention provides a chewing gum base containing a homogeneous composition in solid form comprising a) from 50 to 90% by weight of polyvinyl acetate and b) from 10 to 50% by weight of vinyl acetate-vinyl laurate copolymer, the weight percentage based on the total weight of the composition.

Abstract: The present disclosure relates to an isolated yeast strain deposited as NRRL Y-50184. The present disclosure also relates generally to methods of manufacturing of products, including a fermented beverage or a fermented food using yeast cell from the isolated yeast strain or a cell culture derived from the strain.

Abstract: According to the invention, there is provided barley-derived beverages characterized by notably reduced levels of both dimethyl sulfide (DMS) and/or its precursor S-methyl-L-methionine (SMM), or lacking said compounds. In addition, the invention relates to methods for producing the above-mentioned beverages—and also to barley plants useful in the preparation of such beverages, as well as other plant products prepared from said plants. Utilization of the invention clears the way for making improved production procedures of beverages with improved taste profiles, and promises also for notable reductions in the thermal energy input for production of beer.

Abstract: A system and method for manufacturing low and non-fat sour cream products is provided. The system may utilize a separation technique to separate liquid whey in cultured milk or fat free milk from the solid matter resulting in light or fat free sour cream. The resulting sour cream has the consistency of sour cream without utilizing additional thickening and emulsifying ingredients. The separation can be accomplished with a plurality of separation techniques including centrifuge, reverse osmosis, ceramic centrifuge and the like.

Abstract: The present disclosure provides crumb of the type used in making milk and white chocolates with enhanced flavor and/or aroma. It has been found that adding alpha-dicarbonyls, e.g., 2- or 3-carbon alpha-dicarbonyls, can add noticeable caramel and/or toffee notes to the flavor and/or the aroma of the crumb without a concomitant increase in less desirable flavors and aromas, such as burnt or earthy notes.

Abstract: Fruit juices, purees, and other food products are provided for the healthy-product market. A part of the available sugars in the fruit products is converted to non digestible polymers, thereby lowering the energetic content and simultaneously increasing the nutritional value by forming prebiotic components in the product stables in juices. Further provided is a method of manufacturing juices and purees, enabling to preserve all components but sugars naturally occurring in the fruit.

Abstract: The present disclosure relates to nutritional compositions for pediatric subjects, such as children's nutritional products and infant formulas, comprising a protein source, a fat source, and a source of ?-1,3-glucan.

Abstract: The present disclosure relates to milk-based nutritional compositions for pediatric subjects, such as children's nutritional products and infant formulas, comprising a protein source, a fat source, a carbohydrate source, and a source of ?-1,3-glucan.

Abstract: Methods and compositions for the production of food compositions, oils, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing food compositions, and transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.

Abstract: A phospholipase C enzyme having the ability to hydrolyze a phospholipid in both acidic and around neutral ranges and in a citrate buffer solution, as well as having a degree of heat stability, and having a property not to hydrolyze phosphate esters not containing lipid moieties. The phospholipase C enzyme shows activity from acidic to neutral pH and does not substantially hydrolyze any phosphate esters except for phospholipids.

Abstract: The present invention relates to an isotonic energy drink with an osmolality value between 240 and 300 per litre of drink, comprising the following components: a) almonds b) fruit juice and/or plant extracts c) sucrose d) water.

Abstract: An enzyme resistant starch type III having a melting point or endothermic peak of at least about 140° C. as determined by differential scanning calorimetry (DSC) is produced in yields of at least about 25% by weight, based upon the weight of the original starch ingredient. A gelatinization stage, nucleation/propagation stage, and preferably a heat-treatment stage are used to produce reduced calorie starch-based compositions which contain the enzyme resistant starch type III. The high melting point of the enzyme resistant starch permits its use in baked good formulations without substantial loss of enzyme resistance upon baking. A gelatinized, starch-based bulking agent having at least 30% by weight of the enzyme-resistant starch may be used in bar-type, extruded, sheeted, or rotary molded food products. The melting enthalpy of the bulking agent may be from about 0.5 to about 4 Joules/g and its water-holding capacity may be less than 3 grams.

Abstract: The present invention is directed to a cocoa-derived material comprising a soluble cocoa powder and a cocoa extract, wherein said extract comprises more than 25 wt % based on the extract of polyphenols. The cocoa-derived material can be a syrup, a ready to use beverage or a powder composition. The invention also relates to uses of this cocoa-derived material for preparing carbonated beverages containing cocoa. The invention further relates to a carbonated beverage comprising said cocoa-derived material and to methods for preparing such cocoa-derived materials and beverages.

Abstract: A food formulation for treating malnourished individuals is provided. The food formulation may be customized to specific target consumer groups. The food formulation further may comprise a majority of locally available ingredients. In some embodiments, a food formulation is provided comprising proteins, fats, carbohydrates, and nutritional ingredients, and having a relatively high energy content.

Abstract: The present embodiments generally relate to beverages with enhanced flavors and aromas and method of making same. Some embodiments of the present disclosure are directed to soluble coffee and methods of making soluble coffee with improvements in such qualities as taste and aroma.