Patents Issued in February 18, 2014
  • Patent number: 8652052
    Abstract: In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: February 18, 2014
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Naoe Tatara, Kimihisa Aihara, Shinji Mino, Hiroshi Koizumi, Shoichi Hayashida, Taisuke Oguchi, Junichi Shimada, Shoichi Sudo, Osamu Tochikubo, Hidetoshi Miura
  • Patent number: 8652053
    Abstract: In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: February 18, 2014
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Naoe Tatara, Kimihisa Aihara, Shinji Mino, Hiroshi Koizumi, Shoichi Hayashida, Taisuke Oguchi, Junichi Shimada, Shoichi Sudo, Osamu Tochikubo, Hidetoshi Miura
  • Patent number: 8652054
    Abstract: In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: February 18, 2014
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Naoe Tatara, Kimihisa Aihara, Shinji Mino, Hiroshi Koizumi, Shoichi Hayashida, Taisuke Oguchi, Junichi Shimada, Shoichi Sudo, Osamu Tochikubo, Hidetoshi Miura
  • Patent number: 8652055
    Abstract: A pulse wave data correcting method in an electronic hemomanometer which is designed to time-differentiate signals each formed by superposing a pulse wave amplitude component on a cuff pressure, to compute an envelope consisting of the time-differentiated signals, to detect the maximal value in the computed envelope, to sort the time-differentiated signals generated prior to the maximal envelope value in ascending order, to sort the time-differentiated signals generated after the maximal envelope value in descending order, and to form an envelope consisting of the sorted time-differentiated signals.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: February 18, 2014
    Assignee: Shisei Datum Co., Ltd.
    Inventor: Yukiyoshi Saitou
  • Patent number: 8652056
    Abstract: A deflation control valve that automatically varies the rate of gas flow through said control valve to maintain a constant deflation rate during the deflation or exhaust of gas held in a closed pressurisable vessel to which said valve is connectable, wherein said control valve is manually adjustable to set the deflation rate.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: February 18, 2014
    Assignee: A. C. Cossor & Son (Surgical) Limited
    Inventor: David Anthony Edgerley
  • Patent number: 8652057
    Abstract: A blood pressure cuff is defined by a first sheet, having an opening, and a second sheet. The second sheet is attached to a bottom of the first sheet to form an interior inflatable portion between the first sheet and the second sheet, with the opening of the first sheet fluidly interconnecting the interior inflatable portion with an exterior of the cuff. The blood pressure cuff is made from a single type of material and can be recycled, biodegradable, or composted.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: February 18, 2014
    Assignee: Welch Allyn, Inc.
    Inventors: Robert L. Vivenzio, Ian K. Edwards, Raymond A. Lia, Jeffrey Perkins, Sean R. Karla
  • Patent number: 8652058
    Abstract: A blood vessel pressing cuff includes a strap surrounding a body part, a first actuator disposed on the strap and including a first shape memory alloy which changes to a first shape memorized in advance, at a temperature equal to or higher than a first temperature, and a second actuator disposed on the strap and including a second shape memory alloy which changes to a second shape memorized in advance, at a temperature equal to or higher than a second temperature that is different from the first temperature. If the first shape memory alloy changes to the first shape, pressure applied to the body part surrounded by the strap is increased. Even when the first shape memory alloy changes to the first shape, if the second shape memory alloy changes to the second shape, the pressure applied to the body part surrounded by the strap is reduced.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: February 18, 2014
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Youn-ho Kim, Kun-soo Shin, Hong-sig Kim, Byung-hoon Ko
  • Patent number: 8652059
    Abstract: A cuff includes a cuff main body portion and a gripping portion provided on an outer peripheral surface of the cuff main body portion. The cuff main body portion includes an air bladder, a tightening belt wrapped around an outer side of the air bladder, and a wrapping length adjustment mechanism for variably adjusting a wrapping length of the tightening belt. The wrapping length adjustment mechanism has a bias spring for pulling and biasing the tightening belt in a direction in which the wrapping length of the tightening belt is shortened, a first restriction portion for restricting extension of the wrapping length, and a second restriction portion for restricting shortening of the wrapping length. The gripping portion includes a push button for switching actions of the two restriction portions. In this configuration, the cuff may be easily attached to a measurement site regardless of the circumferential length of the site.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: February 18, 2014
    Assignee: OMRON HEALTHCARE Co., Ltd.
    Inventors: Yoshihiko Sano, Chisato Uesaka, Bo Zhao
  • Patent number: 8652060
    Abstract: A perfusion trend indicator inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. Perfusion values are derived corresponding to the pulses. Time windows are defined corresponding to the perfusion values. Representative perfusion values are defined corresponding to the time windows. A perfusion trend is calculated according to differences between representative perfusion values of adjacent ones of the time windows.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: February 18, 2014
    Assignee: Masimo Corporation
    Inventor: Ammar Al-Ali
  • Patent number: 8652061
    Abstract: Visible light is a treatment option for Segmental Vitiligo (SV), and visible light-induced repigmentation is associated normalization of sympathetic. Currently it is difficult to predict individual patient's response to visible light therapy. Therefore, the present invention uses the Laser Doppler Flowmeter to serve as a response predictor for visible light on treating SV. The present invention recruited 14 Segmental Vitiligo patients for evaluating clinical information. FirstLaser Doppler Flowmeter was used to evaluate the cutaneous blood flow of SV lesion and contralateral normal skin, and then treated them with visible light irradiate, cold-stress, rewarmed, and recorded the change of skin blood flow, finally the patients received regular visible light treatment for 3 months, and patients have a sign of repigmentation after the treatment.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: February 18, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Hsin-Su Yu, Cheng-Che Lan, Wei-Tai Yu
  • Patent number: 8652062
    Abstract: A multi-function electronic necklace includes an Mp3 player with built in wifi connectivity and GPS voice-command in a uniformly dimensioned lanyard which passes simply for a decorative necklace. The necklace includes a microphone and a receptacle for attachment of a Bluetooth headset.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: February 18, 2014
    Inventor: Addam Holder
  • Patent number: 8652063
    Abstract: Equipment (10) for non-invasively measuring a physiological process includes at least one receiver (12) to be placed relative to a body of a subject being examined to detect at least one signal from the body of the subject. A discrimination unit (20.1) determines if the at least one signal is a signal of interest associated with the physiological process. A processor (20) processes the signal of interest to enhance the signal of interest and suppresses other received signals that are not of interest.
    Type: Grant
    Filed: July 5, 2010
    Date of Patent: February 18, 2014
    Assignee: Heard Systems Pty Ltd
    Inventors: Gaetano Gargiulo, Jonathan Craig Tapson, Richard William Shephard
  • Patent number: 8652064
    Abstract: This disclosure describes an apparatus and method for measuring analytes in exhaled air. The device contains an inlet through which exhaled air is received. A tube, having a number of different paths running throughout the device, is coupled to the inlet which enables the exhaled air to be re-circulated through the device. At least one portion of the tube is configured in a non-linear fashion. This particular portion of the tube may be used to temporarily store a sample of the exhaled air. The device also contains a converter configured to partially convert an analyte in the exhaled breath from a first state to a second state as the exhaled air is being re-circulated. An analyte sensor is also included to measure the levels of the converted analyte in the exhaled breath.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: February 18, 2014
    Assignee: Covidien LP
    Inventors: Lockett E. Wood, Jr., Ron J. Kadlac, John Andrew Battista
  • Patent number: 8652065
    Abstract: Detecting transitions in a breathing cycle which includes using a second derivative 54 of a flow waveform 51 to find breathing transitions 51c in the waveform 51.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: February 18, 2014
    Assignee: Fisher & Paykel Healthcare Limited
    Inventor: Mark Renfrew Titchener
  • Patent number: 8652066
    Abstract: Techniques for detecting stress urinary incontinence use a pressure sensing catheter the electrical indications of which are applied to a processing unit for detecting pressure levels generated during involuntary coughs. The involuntary coughs are induced preferentially by using a nebulized composition of L-tartrate in a pharmaceutically acceptable carrier. The area under the curve generated from pressure samples is calculated and used in conjunction with the detection of urine leakage to determine the existence of stress urinary incontinence.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: February 18, 2014
    Assignee: Pneumoflex Systems, LLC
    Inventors: W. Robert Addington, Robert E. Stephens
  • Patent number: 8652067
    Abstract: The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: February 18, 2014
    Assignee: Histologics, LLC
    Inventors: Neal Marc Lonky, Martin L. Lonky
  • Patent number: 8652068
    Abstract: An integrated lancet and testing striplet for measuring a body analyte level in a health care regimen includes a skin piercing member and an analyte sensor coupled together.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: February 18, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Alexander G. Ghesquiere, Clive Nicholls, John J. Cabrall, Scott A. Matula, Simon Andrew Hector, Javier Prieto, Adrian Petyt, Geoffrey Roger Chambers
  • Patent number: 8652069
    Abstract: Apparatus for eliciting a blood sample comprises: a member rotatably mounted on a shaft and configured to rotate between a first position and a second position; and a curved lancet protruding from the member and configured to co-rotate with the member such as to provide skin penetration by the lancet when the member is in the second position. At least 1 mm of the end portion of the curved lancet is coincident with a line that is concentric with respect to the shaft.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: February 18, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Ross MacArthur, Frank Richter
  • Patent number: 8652070
    Abstract: According to some exemplary embodiments, a method or system can involve associating a plurality of biokinetographic comparison results with a first specific dysfunction from a group of specific dysfunctions, each of the biokinetographic comparison results obtained from a comparison of a biokinetographic value to a standard for a corresponding biokinetographic variable.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: February 18, 2014
    Assignee: University of Virginia Patent Foundation
    Inventor: Mark E. Williams
  • Patent number: 8652071
    Abstract: According to some exemplary embodiments, a method or system can involve associating a plurality of biokinetographic comparison results with a first specific dysfunction from a group of specific dysfunctions, each of the biokinetographic comparison results obtained from a comparison of a biokinetographic value to a standard for a corresponding biokinetographic variable.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: February 18, 2014
    Assignee: University of Virginia Patent Foundation
    Inventor: Mark E. Williams
  • Patent number: 8652072
    Abstract: A kinematic system is described. The kinematic system includes a kinematic device for attachment to a subject's body part. The kinematic device projects a light line, and a movement of the light line is used to evaluate a movement, posture, or balance of the subject.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: February 18, 2014
    Assignee: Stimson Biokinematics, LLC
    Inventors: Wendy Stimson, John Caldwell
  • Patent number: 8652073
    Abstract: The present invention relates to a device for treatment of an ocular pathology, the device comprising at least one eye ring wherein the proximal end of said eye ring is suitable to be applied onto the globe and means to generate ultrasound beam fixed on the distal end of the eye ring, said means to generate ultrasound beam presenting a concave segment shape conformed along a single curvature corresponding to a single direction wherein the concavity is designed to be tuned towards the eyeglobe.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: February 18, 2014
    Assignee: Eye Tech Care
    Inventors: Fabrizio Romano, Cyril Lafon, Jean-Yves Chapelon, Françoise Chavrier, Alain Birer, Laurent Farcy, Philippe Chapuis
  • Patent number: 8652074
    Abstract: A walking assist device which assists the knee joint with well synchronizing with the upper leg motion during the swing phase at low cost may be provided. The walking assist device comprises an upper link, a lower link, a rotary joint, an actuator, and a controller. The upper link is to be attached to an upper leg of a user. The lower link is to be attached to the lower leg of the user. The rotary joint swingably connects the lower link to the upper link. The rotary joint is coaxially aligned with the user's knee joint when the user wears the walking assist device. The actuator swings the lower link relative to the upper link. The controller controls the actuator so that the lower link guides the user's walking motion.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: February 18, 2014
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventor: Masahiro Doi
  • Patent number: 8652075
    Abstract: In a walking assistance device for providing a walking assistance force to a femoral part of a user, the walking assistance force generated by a power generator is effectively transmitted to the femoral part of the user while avoiding the user from experiencing any undue pressure or discomfort. The walking assistance device includes a rigid femoral support frame having a base end connected to an output end of an electric motor unit and a free end extending from the base end to a position opposite to a front part of the femoral part of the user, and a flexible belt attached to the free end of the femoral support frame to be releasably worn around a circumference of the femoral part of the user at a height corresponding to the free end of the femoral support frame.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: February 18, 2014
    Assignee: Honda Motor Co., Ltd.
    Inventors: Hideaki Takahashi, Taiji Koyama, Hideo Shimizu
  • Patent number: 8652076
    Abstract: A hand movement device comprises a glove for positioning about a hand of a user, a first anchor element adapted to be positioned about a base surface of glove, a second anchor element adapted to be positioned at a tip of a finger portion of the glove, an active spring member positioned between the first and second anchor elements, said active spring member being fixedly secured to said first anchor element and moveable through said second anchor element to thereby allow said spring member to bend about a joint of the finger when said finger is flexed, an activating element positioned adjacent the active spring member to heat or cool said active spring member thereby causing the spring member to bend or straighten, and an intermediary support device for housing said spring element and for connecting the first anchor element to said second anchor element.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: February 18, 2014
    Assignee: The Johns Hopkins University
    Inventors: Edward M. Land, H. Lee Mantelmacher, Rebecca German, Marlis Gonzalez-Fernandez, Gad Alon, John Staehlin, Ken Silver, Wayne E. Moore
  • Patent number: 8652077
    Abstract: Systems and methods for determining depth of compressions of a chest of a patient receiving chest compressions. A field detector is used having at least two coils at a fixed distance from each other.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: February 18, 2014
    Assignee: Physio-Control, Inc.
    Inventor: Corey Centen
  • Patent number: 8652078
    Abstract: A shower head with water-powered vibrating function wherein a diverting member is disposed in the water diversion chamber which is operable by a diverting member actuating means between a normal shower position and a massage shower position. At the normal shower position the diverting member diverts water flow received from the water diversion chamber inlet to leave the water diversion chamber through the first water diversion chamber outlet for exiting the shower head through a first water outlet; and at the massage shower position, the diverting member diverts water flow received from the water diversion chamber inlet to leave the water diversion chamber through the second water diversion chamber outlet for entering the turbine chamber for rotating the turbine and thereafter leaving the turbine chamber to exit the shower head through a second water outlet.
    Type: Grant
    Filed: April 28, 2010
    Date of Patent: February 18, 2014
    Assignee: Brand New Technology Ltd.
    Inventor: Man Hon Lee
  • Patent number: 8652079
    Abstract: A compression garment for applying compression therapy to a wearer's body including a compression sleeve having a proximal edge and a distal edge. The sleeve includes at least one bladder. A tube is attached to the bladder. A connector on the tube connects the tube to a source of compressed fluid for inflating the bladder. The distal edge of the compression sleeve has a first portion and a second portion jutting distally from the first portion.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: February 18, 2014
    Assignee: Covidien LP
    Inventor: Richard P. Rego, Jr.
  • Patent number: 8652080
    Abstract: An apparatus and method of use for a wrist extension brace, intended to be used to position, secure, stabilize, and extend a patient's wrist for the purpose of assisting cannulation of blood vessels in the wrist and forearm. The apparatus generally includes a frame having a fixed dorsiflexion angle and means for cushioning a patient's hand, wrist and forearm and means of attaching such to the wrist extension brace. The method of use includes the steps of attaching the apparatus to a patient's wrist and adjusting it after such attachment.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: February 18, 2014
    Assignee: Semler Technologies, Inc.
    Inventors: Philip Benz, Robert Henry Niemeyer, III, Matthew Semler
  • Patent number: 8652081
    Abstract: A lumbar traction device that can alleviate lower back pain is provided. The device includes a harness or girdle that is fitted about the torso region of a patient and an adjustable support assembly in the form of adjustable legs that allow the degree of traction to be adjusted by the patient. The device is safe and easy to use by a patient without constant medical supervision and is particularly suitable for use in domestic or office environments.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: February 18, 2014
    Inventor: Marcus Andrew Rawlings
  • Patent number: 8652082
    Abstract: A proposed blood treatment apparatus includes: a blood treatment unit, at least one fluid pump and at least one blood pump. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, at least one of the fluid pumps is configured to control the operation of at least one blood pump via the blood treatment fluid. Moreover, at least one of the blood pumps is integrated into a joint apparatus element, which includes the blood treatment unit. Thus, this blood pump and the unit may be mounted as well as be discarded jointly.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: February 18, 2014
    Assignee: Gambro Lundia AB
    Inventors: Lennart Jönsson, Olof Jansson, Mattias Holmer, Eddie Nilsson
  • Patent number: 8652083
    Abstract: The anti-obesity stent includes a tubular structure having outer and inner surfaces and proximal and distal ends. The tubular structure is sized to fit within a duodenum in substantially coaxial relation therewith. The tubular structure is impervious or semi-permeable to digestive substances and chyme within the duodenum. The anti-obesity stent includes a transport structure at least a part of which is coincident with or connected to the outer surface. The transport structure extends to the distal end of the tubular structure. At least one retainer structure is connected to the tubular structure. The retainer structure secures the tubular structure within the duodenum such that the transport structure is positioned to receive digestive fluids from a papilla of Vater on an inner surface of the duodenum. The transport structure provides a conduit for the digestive fluids therein to flow to the distal end.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: February 18, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Barry Weitzner, Taryn Deneault, Katie Krueger, Claude Clerc, Harold M. Martins, William Bertolino
  • Patent number: 8652084
    Abstract: A hemodialytic angioacess device for implantation in dialysis patients, comprising an arteriovenous (AV) shunt, anastomotic valves that connect the AV shunt to blood vessels, a valve control system and an integrated surveillance system that measures flow conditions in the blood vessels at the AV shunt, preferably when the valves are closed and the patient is not undergoing dialysis treatment. The flow condition data, which may include data representing the flow rate, pressure, volume and velocity of blood flowing through the vessels, is stored in a memory and transmitted to a health care provider or technician on demand. The data can be used to calculate and monitor important physiological parameters, such as compliance and resistance, for the blood vessels, and help detect and identify dangerous conditions, such as turbulence and stasis, which can contribute to AV shunt failure, vessel injury and other serious complications for the patient.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: February 18, 2014
    Assignee: Indiana University Research and Technology Corporation
    Inventor: Ajibola George Akingba
  • Patent number: 8652085
    Abstract: A membrane actuator device includes a housing with an entrance port and an exit port connected by a fluid flow passageway. A gas generation chamber is disposed within the housing, the gas generation chamber comprising a first opening and a gas generating element. A membrane actuation chamber has a second opening and may be defined at least in part by a flexible membrane configured to deflect and affect fluid flow through the fluid flow passageway. A barrier spans the width of the first opening of the gas generation chamber and is disposed in a manner that reduces the likelihood that gas molecules will pass from the gas generation chamber to the membrane actuation chamber.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: February 18, 2014
    Assignee: Alcon Research, Ltd.
    Inventors: Michael L. Gelvin, Cesario P. Dos Santos
  • Patent number: 8652086
    Abstract: The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: February 18, 2014
    Assignee: Abbott Medical Optics Inc.
    Inventors: James Gerg, Carina Reisin
  • Patent number: 8652087
    Abstract: Very accurate measurements of mass transfer can be made rapidly by permitting diffusion of an agent desired to be measured into or out of a small, very precisely known volume of a microdialysis probe, then rapidly pumping or flushing (“pulsing”) the probe with a known volume of fluid as a single pulse. The diffusion and pulsing may be repeated. The method, hereinafter called pulsatile microdialysis (PMD) to distinguish it from prior art continuous flow microdialysis, is useful for measurements in a number of processes, including protein binding, adsorption to binding agents such as activated charcoal, release from microemulsion drug delivery systems, determination of drug diffusion coefficients and concentrations, and for various other purposes. The method is based on mathematical manipulation of Fick's Laws. Resulting equations were verified against experimental data using methazolamide, warfarin and benzocaine as test drugs.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: February 18, 2014
    Inventor: Robert A. Bellantone
  • Patent number: 8652088
    Abstract: Very accurate measurements of mass transfer can be made rapidly by permitting diffusion of an agent desired to be measured into or out of a small, very precisely known volume of a microdialysis probe, then rapidly pumping or flushing (“pulsing”) the probe with a known volume of fluid as a single pulse. The diffusion and pulsing may be repeated. The method, hereinafter called pulsatile microdialysis (PMD) to distinguish it from prior art continuous flow microdialysis, is useful for measurements in a number of processes, including protein binding, adsorption to binding agents such as activated charcoal, release from microemulsion drug delivery systems, determination of drug diffusion coefficients and concentrations, and for various other purposes. The method is based on mathematical manipulation of Fick's Laws. Resulting equations were verified against experimental data using methazolamide, warfarin and benzocaine as test drugs.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: February 18, 2014
    Inventor: Robert A. Bellantone
  • Patent number: 8652089
    Abstract: The present invention provides a system and a method for distending a body tissue cavity of a subject by continuous flow irrigation such that minimal or negligible fluid turbulence is present inside the cavity, such that any desired cavity pressure can be created and maintained for any desired outflow rate. The present invention also provides a method for accurately determining the rate of fluid loss, into the subject's body system, during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation or flow rate sensor. The system and the methods of the present invention described above can be used in any endoscopic procedure requiring continuous flow irrigation few examples of such endoscopic procedures being hysteroscopic surgery, arthroscopic surgery, trans uretheral surgery, endoscopic surgery of the brain and endoscopic surgery of the spine.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: February 18, 2014
    Assignee: Arthrex, Inc.
    Inventors: Atul Kumar, Alka Kumar
  • Patent number: 8652090
    Abstract: The devices and methods shown provide for the minimization of extravasation during arthroscopic surgery. The anti-extravasation surgical portal plug allows a surgeon to drain excess fluids from the soft tissue surrounding the surgical field during arthroscopic surgical procedures.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: February 18, 2014
    Assignee: Cannuflow, Inc.
    Inventor: Theodore R. Kucklick
  • Patent number: 8652091
    Abstract: A fluid injection device includes: a pulse generation section that includes a fluid chamber whose volume is changeable, and an inlet flow passage and an outlet flow passage that are connected to the fluid chamber; a first connection flow passage connected to the outlet flow passage, having an end portion; a second connection flow passage connected to the inlet flow passage; a fluid injection opening formed at the end portion of the first connection flow passage, having a diameter smaller than the diameter of the outlet flow passage; a connection flow passage tube including the first connection flow passage and having rigidity adequate to transmit pulses of fluid flowing from the fluid chamber to the fluid injection opening; and a pressure generation section that supplies fluid to the inlet flow passage.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: February 18, 2014
    Assignees: Seiko Epson Corporation, Tohoku University
    Inventors: Takeshi Seto, Kazuo Kawasumi, Kazuyoshi Takayama, Seyed Hamid Reza Hosseini
  • Patent number: 8652092
    Abstract: The invention relates to applicators (1) for implantation of an implant, having a cylinder (2) and a plunger (3) displaceably mounted therein, which plunger (3) has a pusher plunger (31) for pushing the implant out of a cannula, the cannula being mounted on a cylinder part, the cylinder part (4) being movably guided in the cylinder (2), there being provided a gear mechanism (5) which couples the plunger (3) to the cylinder part (4), a movement of the plunger (3) relative to the cylinder (2) being converted into an opposite movement of the cylinder part (4).
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: February 18, 2014
    Assignee: Acino AG
    Inventor: Oliver Bussmann
  • Patent number: 8652093
    Abstract: Medical pumps may obtain programming data from a database through the use of a remote query process which allows the individual pump to flexibly request data from existing hospital databases, to identify the necessary information in those databases, and to convert that data for use without the need for manual programming or a centralized pump control system.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: February 18, 2014
    Assignee: Zyno Medical, LLC.
    Inventors: Chaoyoung Lee, Mei Zhang
  • Patent number: 8652094
    Abstract: The present invention relates to a syringe (20) defining a reservoir (21) for containing a liquid and comprising an end-piece (10) encompassing a channel (11) providing a passageway for the transfer of the said liquid, characterized in that the said channel (11) comprises two portions, a first portion (12) and a second portion (13), the said first portion (12) extending from the free distal end (14) of the end-piece (10) in the direction of the reservoir (21), and the said second portion (12) extending between the first portion (12) of the channel (11) and the proximal end (15) of the end-piece (10) and connecting the said first portion (12) to the reservoir, the said first portion (12) having an average diameter that is greater than the average diameter of the said second portion (13).
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: February 18, 2014
    Assignee: Becton Dickinson France
    Inventors: Olivier David, Emeric Mermet
  • Patent number: 8652095
    Abstract: A skin retention device 10 for a medical jet-injection unit 20 having a contact face provided with adhesive 12 in the area surrounding and close to the injection opening(s) 11 of the nozzle 21 which ensures good contact between the nozzle 21 and the skin 30 of a subject in the area chosen for an injection. The injection force can be lowered dramatically. In case of two-stage jet-injections, the initial injection force can be lowered because the skin retention close to the injection point significantly reduces the energy consuming elastic expansion of the skin 30 in the injection area, and the second injection force can be lowered because of the high degree of fixed positioning of the injection opening of the nozzle 21 relative to the injection channel in the skin 30 made during the initial injection stage.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: February 18, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Torben Stroem Hansen, Jens Erik Poulsen
  • Patent number: 8652096
    Abstract: An ingestible material delivery device for sequentially delivering first and second ingestible materials to a user through a feeding tube provides a tube body having first and second chambers separated by a seal. A puncture tool is disposed in the second chamber extending toward the seal. The puncture tool engages and disrupts the seal when the second chamber is compressed. In some embodiments, the second chamber includes a plurality of interconnected bellows operable for axial compression of the second chamber. Another embodiment of a delivery device provides a tube body having first and second chambers with exit nozzles extending in opposite flow directions. A method of sequentially delivering first and second ingestible materials to a user through a feeding tube is also provided.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: February 18, 2014
    Assignee: Mead Johnson Nutrition Company
    Inventors: John D. Alvey, Marc S. Velmer
  • Patent number: 8652097
    Abstract: A method of combining a drug in a first container and a liquid in a second container includes placing the first container and the second container in fluid communication with a housing, combining the liquid and the drug in the first container, transferring the liquid and the drug from the first container to the housing, and transferring the liquid and the drug from the housing to a third container.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: February 18, 2014
    Assignee: B. Braun Melsungen AG
    Inventor: Freddie Eng Hwee Lee
  • Patent number: 8652098
    Abstract: A balloon catheter having a radiopaque coil embedded in the catheter's body corresponding to a landmark of the balloon or other location on the catheter body. The radiopaque coil can be viewed under fluoroscopy to located the balloon or other structure of the catheter. The coil can be readily inserted in the manufacturing process by inserting it between two layers that form the catheter body, and then sealing the coil inside the catheter at the desired location. This facilitates both the manufacturing process and prevents the marker from being dislodged during the manufacturing, navigation, or inflation process.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: February 18, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Thomas Haslinger
  • Patent number: 8652099
    Abstract: A medical device for the delivery of treatment fluid to body vessels is described. The device has a distal (21) and a proximal (20) end with a self-expanding, hollow tubular member (9) and a delivery catheter (10) suitable for deploying a self-expanding, tubular member (9). The tubular member (9) is configured to expand radially to form a central part (11) flanked by two annular ridges, which creates, in situ, an annular lumen that can apply treatment fluid locally to a vessel and a passageway that can maintain the flow of blood through the vessel. The device is particularly suited for minimally invasive and repeatable organ perfusion. A method for organ perfusion is also disclosed.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: February 18, 2014
    Assignee: Medical Device Works NV SA
    Inventors: Joost J. Fierens, Eric Marcoux, Malika Omari
  • Patent number: 8652100
    Abstract: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: February 18, 2014
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventor: Toby Cowe
  • Patent number: 8652101
    Abstract: The invention relates to an implantation device for implanting a sensor element for detecting at least one analyte in a bodily fluid or body tissue. The implantation device comprises at least one cannula for piercing a skin surface of a patient. The cannula has at least one holding area for holding the sensor element. The implantation device furthermore has at least one hydraulic container, connected to the cannula, for holding a hydraulic fluid and at least one pressure generation device. The pressure generation device is designed to apply pressure to the hydraulic fluid, wherein the sensor element can be transferred from the cannula into the body tissue using the hydraulic fluid.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: February 18, 2014
    Assignee: EyeSense AG
    Inventors: Achim Müller, Peter Herbrechtsmeier