Abstract: A medical blood pressure transducer that provides an identifier to a monitor that conveys characteristics of the transducer. The monitor can use the information to decide whether to function, or in calibration of the system. The transducer may be part of a disposable blood pressure monitoring system, and may include two transducers closely-spaced to provide two separate but identical outputs. In this way, the transducer may be connected to both a patient monitor and a cardiac output monitor at the same time measurements from a single line can be simultaneously supplied to two separate monitoring devices (for example a patient monitor and a cardiac output monitor). The identifier for the transducer may be circuitry, specifically a resistance/capacitance (RC) combination that possesses a characteristic time constant.

Abstract: A blood pressure information display device for calculating a blood pressure value based on a pulse wave amplitude through the oscillometric method and the like, and displaying the calculated blood pressure value as blood pressure information performs a process of changing a magnitude of a specified pulse wave amplitude of a plurality of extracted pulse wave amplitudes according to the operation by a user (medical staff) when a predetermined instruction is input. A predetermined algorithm is applied to the plurality of pulse wave amplitudes reflecting the change to calculate a reference blood pressure value, and the calculated reference blood pressure value is displayed as the blood pressure information.

Abstract: During a period of servo control, an artery volume of a peripheral site is detected by an artery volume sensor arranged at a peripheral site (site on the peripheral side than a measurement site) of a person to be measured. If an amount of change in the artery volume of the peripheral site or a value of the artery volume is greater than or equal to a predetermined ratio of a reference value at the beginning of the measurement, the servo control and a blood pressure determination process are continued. When detected thereafter that the amount of change in the artery volume of the peripheral site or the value of the artery volume is smaller than the predetermined ratio of the reference value at the beginning of the measurement, the measurement is stopped at the relevant time point.

Abstract: A disposable active pulse sensor has an emitter that generates optical radiation having a plurality of wavelengths, a detector that is responsive to the optical radiation and an unbalanced electrical motor that vibrates when energized. A tape assembly removably attaches the emitter, the detector and the unbalanced electrical motor to a tissue site. The tape assembly also physically mounts the emitter, the detector and the unbalanced electrical motor in a spatial arrangement so that vibration from the unbalanced electrical motor induces pulsatile blood flow within the tissue site, the emitter transmits the optical radiation into the tissue site and the detector generates a sensor signal responsive to the intensity of the optical radiation after attenuation by the pulsatile blood flow within the tissue site.

Abstract: A system, method and device for monitoring the condition of an internal organ, such as a brain, by providing an internal electrode. The internal electrode is operatively connected to at least one surface, external, electrode, and a system handler. A signal is generated between the electrodes such that the electrical properties, including conductivity and impedance among others, can be measured at and across the electrodes. The electrode arrangement allows for continuous monitoring of an internal organ and, where desired, mapping of the electrical properties thereof. The system obtains pressure readings, nodal conductivity and/or electrode impedance to monitor, map and report the condition of the internal organ. A correlation procedure is provided for generating a graphical representation of the condition of an internal organ from the gathered data.

Abstract: Group coherence is facilitated in a group environment, such as a gaming, competitive, cooperative or collaborative environment. In one embodiment, a graphical representation of a scenario may be presented to a plurality of individuals. A physiological measure for each of the plurality of individuals may be sampled and used to track the individuals' heart rhythm patterns. A current group coherence level for the plurality of individuals may then be determined, where the group coherence level corresponds to a collective degree to which said plurality of heart rhythm patterns exhibit a sine waveform. In one embodiment, an appropriate modification to the scenario may be determined, where the modification is based on the current group coherence level. The updated graphical representation of the scenario may then be presented to the plurality of individuals.

Abstract: A medical device system and method that includes receiving an A2 heart sound signal from a first external acoustic sensor, receiving a P2 heart sound signal from a second external acoustic sensor, determining at least one A2 heart sound signal parameter from the A2 heart sound signal, determining at least one P2 heart sound signal parameter from the P2 heart sound signal, and based on the at least one P2 heart sound signal parameter, estimating pulmonary arterial pressure.

Abstract: An electrode for applying electric fields to a patient includes a plurality of ceramic elements (e.g., ceramic discs) that are designed to be positioned against the patient's skin. Electrical connections are made to the ceramic elements (e.g., using a flex circuit). Temperature sensors (e.g., thermistors) are preferably provided at at least some of the ceramic elements to sense the temperature at the skin beneath the ceramic elements, so that appropriate action can be taken if an overtemperature condition is detected.

Abstract: The invention relates to systems and methods for estimating a response of at least a part of a physiological system to a first deterministic stimulus signal. The methods include separating a measured first signal into a plurality of segments, each segment representing a response of the physiological system to a corresponding portion of the first stimulus signal and generating a template signal representing the plurality of segments. The methods further include calculating a measure of similarity of each segment in the plurality of segments to the template signal to provide a set of scalar quantities, and determining a metric representing a characteristic of the response of at least a part of the physiological system to the first stimulus signal.

Abstract: A surface or bulk acoustic wave device can be implanted in or worn on a human or animal body to monitor various parameters thereof. The device comprises a pair of interdigitated transducers spaced apart over the surface of a piezo-electric substrate that is exposed to the parameter to be monitored. The device is interrogated by a radio-frequency signal being supplied to one of the transducers and detected after reflection by the other transducer. The parameter is measured by comparison of the supplied and received signals.

Abstract: A pressure sensor (10 for medical applications comprises a silica optical fiber extrinsic Fabry-Perot interferometric (EFPI) pressure sensor (2) and an in-fiber Bragg grating (FBG, 3). The cavity of the EFPI pressure sensor (2) is formed by the end face of the FBG (3), a glass capillary (5) and a glass diaphragm (6). The glass diaphragm (6) is secured in place by a fusion splice (7) and the glass capillary (5) by a fusion splice (8). As illustrated, incident light is directed into the FBG 3 and there are reflections in the EFPI pressure sensor (2). Applied pressure causes a deflection of the glass diaphragm (6) and hence modulation of the EFPI sensor (2) cavity. The FBG (3) is used as a reference sensor to eliminate temperature cross-sensitivity of the EFPI pressure sensor (2). The EFPI cavity was fabricated using a 200 ?m silica glass fiber, a 133/220 ?m (inner/outer diameter) silica glass capillary and a standard telecommunication FBG.

Abstract: A disposable tissue removal device comprises a “tube within a tube” cutting element mounted to a handpiece. The inner cannula of the cutting element defines an inner lumen and terminates in an inwardly beveled, razor-sharp cutting edge. The inner cannula is driven by both a rotary motor and a reciprocating motor. At the end of its stroke, the inner cannula makes contact with the cutting board to completely sever the tissue. An aspiration vacuum is applied to the inner lumen to aspirate excised tissue through the inner cannula and into a collection trap that is removably mounted to the handpiece. The rotary and reciprocating motors are hydraulically powered through a foot pedal operated hydraulic circuit. The entire biopsy device is configured to be disposable. In one embodiment, the cutting element includes a cannula hub that can be connected to a fluid source, such as a valve-controlled saline bag.

Abstract: A biopsy device includes a body, a needle, and a cutter. A motor is operable to both move the cutter relative to the needle and actuate a needle firing assembly to retract and fire the needle relative to the body. The biopsy device also includes a needle rotation assembly that is configured to substantially prevent rotation of the needle about the longitudinal axis when the needle is in a proximal position yet permit rotation of the needle about the longitudinal axis when the needle is in a distal position. A valve assembly of the biopsy device includes a slider that selectively couples a secondary lumen in the needle with either atmospheric air or saline based on the longitudinal position of the slider. The cutter passes through the slider.

Abstract: Carbon nanotube needles and needle arrays are described in which the precursor pillars are etched by oxygen plasma treatment to provide tapered and/or sharp-tip needles. Processes, products by process, and devices incorporating the sharp-tip needles are further described.

Abstract: Disclosed are a measurement device and a puncture device that prevent thermal loss and enable decreased cost in laser units. A laser unit (200) of a measurement device (100) is equipped with a lens barrel (210), a laser rod (220) disposed inside the lens barrel (210), a flash lamp (230) which is disposed opposite the laser rod (220) inside the lens barrel (210) and in which an inert gas is sealed inside a hard glass tube (231), and supports (241, 242, 243, 244), which are made from a material with thermal conductivity of 100 W/(mK) or more, at least parts of which are disposed outside of the lens barrel (210), and which support the circumferential surface of the hard glass tube (231) in a housing.

Abstract: A guidewire for a medical device is disclosed. In one embodiment, the guidewire includes a corewire having a proximal end portion and a distal end portion, an elongate shroud disposed about the corewire, the shroud having a distal end, and a plug coupled with the distal end portion of the corewire and the distal end of the shroud, the plug having a distal, non-traumatic tip portion, an interior between the corewire and the shroud being configured to receive a sensor.

Abstract: A guide wire (1) for use with a catheter comprises a core wire (3) terminating in a distal portion (18) of flat ribbon-like construction having respective opposite major surfaces (29,30). A spring (24) is brazed to a distal end (27) of the distal portion (18) and to the core wire (3) at a tapering portion (14). A reinforcing member (38) extends axially along the distal portion (18) from a proximal end (26) of the distal portion (18) to a location (40) for reinforcing the distal portion (18) for in turn increasing its torsional rigidity in order to minimise axial twisting of the distal portion (18).

Abstract: A biomedical interface pressure transducer which is useful for interposing between a limb or tissue and an occlusive band, tourniquet cuff or other biomedical apparatus in order to estimate the pressure and pressure gradient applied to a selected area of the limb or tissue is disclosed. The pressure transducer comprises a modified MEMS pressure sensor and a conformable semisolid body enclosed in a shear relief membrane which translates the pressure applied by the occlusive band to the modified MEMS pressure sensor mounted on a flexible substrate with patterned electrical interconnect tracks allowing the connection of the pressure sensor to digital communication and control circuitry.

Abstract: A fetal movement information processing device and method for accurately grasping and predicting the healthy development state of a fetus, namely, the well-being state of the fetus by adequately detecting and recording information on the fetal movement of a pregnant woman.

Abstract: An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.

Abstract: A sleeve that provides mechanical stimulation to the arm to prevent bone density loss. A primary goal of this product is to prevent bone density loss that occurs during extended space travel. For one embodiment, only the predefined frequency specifications had to be met (between 40 Hz and 60 Hz). By meeting these frequencies for a duration of 30 minutes the product will theoretically prevent the loss of bone density. Additionally, clinical trials will need to be conducted before this product can be marketed. The product includes of several mechanical vibrators attached to a sleeve. The vibrators are small unbalanced-mass motors which are similar to those found in cell phones. The motors are encased in dome shaped housings designed to reduce lateral vibrations along the arm. The product is controlled using an Arduino board attached to the sleeve that actuates the motors. The motors, in turn, provide the specified frequency to the arm for 30 minutes.

Abstract: A device for compressive treatment of a body part includes a compression member, adapted to at least partly encircle the body part, and an actuation unit, arranged to tighten the compression member to provide a compressive force to the body part. The actuation unit includes an active material actuator. There is also disclosed a system comprising such a device and methods for its therapeutic, cosmetic and non-therapeutic use and operation.

Abstract: The apparatus comprises an inflatable sleeve 6 to be wrapped around a limb, typically a thigh, of a patient. The sleeve 6 comprises three inflatable chambers 3, 4, 5. Inflation is controlled by a pump 1 so that the distal chamber 3 is inflated first to a low pressure to act as a tourniquet, followed by inflation of the central chamber 4 to a pressure to drive fluid flow upwards, and then inflation of the proximal chamber 5 to a low pressure to act as a tourniquet and deflating both the distal 3 and central 4 chambers to produce a negative pressure gradient down-stream in the limb causing fluid to be drawn up the limb. This cycle is repeated a number of times over a period of two minutes before allowing the limb to rest for two minutes, resulting in increased mean arterial blood flow.

Abstract: A pannus support member is configured to support and contain a pannus during a surgical procedure to provide unobstructed access to the surgical site and provide, post surgery, a clean site that is exposed to air to promote proper healing.

Abstract: A knee brace for the correction of abnormalities of the knee such as varus or valgus knee, or for the various forms of osteoarthritis, consisting of a support structure with a sole direction of development, that is to say it comprises a single upright (11) for the femoral area and a single upright (12) for the tibial area, these uprights (11, 12) being connected and hinged to a single articulated joint (13), which can be positioned close to one side of the knee, generally the outer side in the case of varus knee or the inner side in the case of valgus knee.

Abstract: A traction device comprises a frame, a first bladder portion, a second bladder portion, a spacer, and a pump. The first bladder expands in an outward direction a distance greater than in a transverse direction. The second bladder expands in an angular direction. The second bladder is positioned generally below and to the side of the first bladder. Upon expanding in the outward direction, the first bladder bears against the back of the user's neck. Upon expanding in the transverse direction, the first bladder applies an angular traction to the cervical spine. Upon expanding in the angular direction, the second bladder bears angularly against the back of the user's upper thoracic region.

Abstract: This invention is related to wound care in humans and animals, and they reduce the use of adhesives. Also allows the process of wound dressing to be faster, easier, and applicable even with one hand. In these models, a support unit and straps are used. These straps are stretchable and attach to a zone of the hook fastener on the support on a detachable, re-attachable basis. In some models the support unit will function as the stabilizer of the system or to make the functions simpler. The main idea is used in making multiple models for use in different areas of the body. In other models the unit allows guarding the skin and wound site or for the protection of the wound. All in all, the applicant has tried to introduce units for improving the humans and animals life.

Abstract: The invention is directed to the removal of serum gal-3 from circulation by plasmapheresis using gal-3 binding agents in either a fixed bed, or in a form easily removed, such as by being complexed with magnetic particles. This method, on its own, brings a sharp reduction and relief from the inflammation and fibroses that can be induced by circulating gal-3. The process may be combined with the administration of gal-3 binding agents, such as modified citrus pectin, to further lower unbound gal-3 levels, to the point where gal-3 in the tissues may be addressed. This method may also be combined with removal of TNF receptors to provide an effective treatment for cancer.

Abstract: Drainage devices for draining a fluid from a patient during treatment of a medical condition body are disclosed. The drainage devices comprise a body defining at least one conduit through the body from a distal end of the body to a proximal end of the body. The body comprises at least one carbon-based structure configured to inhibit growth of fibroblasts in the conduit when the fluid flows through the conduit. Example embodiments of the drainage device may include an ophthalmic shunt, a hydrocephalus shunt, an artificial mesh, an arteriovenous shunt, a thoracic catheter, and a central venous access device.

Abstract: The present invention relates to a biologically active medical device, which includes a matrix seeded with progenitor cells, and then covered by ciliated tissue. The matrix is capable of enabling cellular migration. The ciliated tissue is ependymal cells that express at least one of tight junctional complexes, zonula adherens, and gap junctions. The progenitor cells include subpendymal progenitor cells. In some cases the progenitor cells include stem cells, and the ciliated tissue includes at least one of Choroid cells, tanacytes, and circumventricular organs. In some embodiments, the medical device is oriented into a tubular structure in order to form a cerebrospinal shunt. Additional cells and structures may be imbedded within the matrix, such as glia, endothelial cells, stem cells, and blood vessels. The medical device may also be incorporated into a bioreactor including a flexible inner tube defining an anthropomorphically shaped lumen.

Abstract: An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is well suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of the arteriovenous graft. In one embodiment, a subcutaneous arteriovenous graft system is described. The system includes an arteriovenous graft having an arterial end and an opposite venous end with a first valve device positioned at the arterial end of the arteriovenous graft and a second valve device positioned at the venous end of the arteriovenous graft. The system also includes an actuator having an accumulator. The actuator is in communication with both the first valve device and the second valve device and is configured to cause each valve device to open or close simultaneously. The accumulator assists in maintaining a generally constant pressure when the actuator causes each valve device to close.

Abstract: Control apparatus for an ultrasonic phacoemulsification handpiece utilizes flow rates and temperature measurements as well as power provided to a handpiece for calculating a matrix of power level duty cycle combination that would not generate sufficient heat to create a burn in eye tissue and either prevent operation of handpiece in the matrix or alert a surgeon of such use.

Abstract: An apparatus for delivering ultrasound energy and a drug solution to a treatment site in a vessel is disclosed. The apparatus includes an elongate, hollow sheath having a distal opening and an energy delivery section at least partially constructed from a material that transmits ultrasound energy. The apparatus also includes a drug delivery lumen positioned along at least a portion of the sheath, the drug delivery lumen having at least one drug delivery port within the energy delivery section. The apparatus further includes an elongate body having an ultrasound element, the elongate body configured to be movably positioned within the sheath, such that ultrasonic energy can be transmitted from the ultrasound element through the energy delivery section.

Abstract: Apparatuses and methods for treating wounds are disclosed. An apparatus for treating wounds is disclosed comprising an instrument for generating a low temperature, atmospheric pressure plasma, a means of flowing gas comprising mixing an inert gas and a reactive gas through the instrument, and a means of contacting the wound with the reactive gases flowing out of the instrument. A method for treating wounds using reactive gases is disclosed. The use of atmospheric pressure plasmas for treating wounds is also disclosed.

Abstract: A dialysis system includes a dialysis instrument; a disposable cassette operable with the dialysis instrument; a dual lumen patient line including dual lumens, the dual lumen patient line connected to the disposable cassette; and a priming sequence in which ends of the dual lumens are connected together, a first pump chamber of the disposable cassette pumps fluid through the dual lumens until fluid reaches a second pump chamber of the disposable cassette.

Abstract: In a pre-filled syringe having an intermediate gasket, a liquid drug is enclosed in the second chamber located on the base end side with respect to the intermediate gasket while a powdered drug is enclosed in the first chamber located on the front end side with respect to the intermediate gasket. The intermediate gasket has at least two layers including a front end layer corresponding to a wall of the first chamber and a base end layer corresponding to a wall of the second chamber, and also has a low water-absorptive layer in the layer on the base end side with respect to the front end layer. The base end layer is formed of a material having low water-absorptivity and not lowering a pH of the liquid drug.

Abstract: Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The distal end of the sheath is maintained in the first, low cross-sectional configuration and expanded using a radial dilatation device. In an exemplary application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as ureteroscopy or stone removal.

Abstract: A balloon and method of making a balloon catheter is provided. The balloon for the balloon catheter may be made by slicing through an integral dilation element on a parison (10). The parison may then be stretched to spread the slices to form wider gaps (20). The gaps define separate dilation element segments (14), which may make the balloon more flexible.

Abstract: A pen needle (521) for a drug delivery device (100) includes a hub (511) and a needle (502) fixedly connected to the hub (511). An outer cover (501) removably receives the hub (511) and the needle (502). A locking member (505) locks the hub (511) and the needle (502) in the outer cover (501). The hub (625) may have a colored portion (629) visible to the user to indicate that the needle (623) has been used.

Abstract: An insertion device, generally used with an infusion set, including a needle being adapted for puncturing at one end and including at the opposite end a hub. The hub includes a handle part and a guard part that are capable of securing the needle through the use of locks. Locking structures are used to secure the insertion device in a position where the needle is covered in a locked position, avoiding unintended contact with the needle.

Abstract: Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball.

Abstract: Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies.

Abstract: An apparatus for preventing blood exposure or contamination upon withdrawal of a hypodermic needle is provided. The apparatus may include a needle having a tip and a shield configured to at least partially entrap the needle tip upon withdrawal of the needle. The apparatus may further include a blood stabilizing material disposed such that upon withdrawal of the needle the blood stabilizing material is disposed in operative association with the needle tip such that blood carried by the needle is prevented from escaping the apparatus. In some exemplary implementations, the blood stabilizing material may be disposed on one or more surfaces of the shield. The shield of the hypodermic needle may include protective device and/or a housing for shielding the needle tip upon withdrawal. The housing may be adapted to at least partially cover the needle tip upon withdrawal of the needle.

Abstract: A needle guard assembly having a resilient arm extending from a base situated to slide along the shaft of a needle. In one implementation the needle guard has an elongate containment member that rides with the resilient arm and is co-operable with the resilient arm to effectuate a covering of the entire distal tip of the needle upon the needle being refracted into the needle guard.

Abstract: A micro-needle array is provided that may be used to deliver a bioactive agent to a therapeutic target. The micro-needle array preferably includes a substrate, a plurality of micro-needles integral with the substrate, and a bioactive agent. At least one micro-needle preferably includes a top surface, a bottom surface, a side surface, and a cavity defined by an inner surface. The bioactive agent may be disposed on the substrate and the plurality of micro-needles. The at least one micro-needle may further include a slit connecting the cavity to an aperture, the slit extending from the top surface to the bottom surface.

Abstract: A method of repositioning an injection port comprises positioning the injection port at a first location in a patient's body and extending fasteners of the injection port to substantially secure the injection port at the first location. The fasteners are then retracted to substantially unsecure the injection port from the first location in the patient's body. The injection port is then moved to a second location in the patient's body. The fasteners are then re-extended to substantially secure the injection port at the second location in the patient's body. The injection port includes a port body. The fasteners are integral with the port body. The fasteners may be selectively extended and retracted relative to the port body. For instance, the fasteners may be pivoted relative to the port body to transition between extended and retracted positions. The extension and retraction of fasteners may be provided through a port applier.

Abstract: The present invention relates to a dressing (1) for protecting the skin around objects projecting out from the skin, the dressing including a first liquid impermeable film layer (2) coated with a skin friendly adhesive (3) on the lower side thereof, i.e. the side intended to adhere to the skin when the dressing is used. According to the invention a body (4) of absorbent material is enclosed between the first film layer (2) and a second liquid impermeable film layer (5), the second film layer being affixed to the first film layer in parts extending beyond the periphery of the body of absorbent material, and the dressing includes an element (8) for facilitating passing of an object projecting out from the skin through the dressing.

Abstract: Test methods for assessing irritation of portions of skin are provided. The method may include irritating a portion of skin by contacting the portion of skin with a chemical irritant; irritating the portion of skin by physical irritation; and assessing erythema or dryness of the portion of skin after irritating the steps. Alternatively, the method may include irritating a portion of skin with a chemical irritant; irritating the portion of skin by physical irritation; treating the irritated portion of skin by wiping the irritated portion of skin with a test sample; and assessing erythema or dryness of the portion of skin after the wiping step. A method of irritating a portion of skin to assess one of erythema and dryness may include irritating a portion of skin with a chemical irritant and irritating the portion of skin by physical irritation.

Abstract: A kit for collecting stool, comprising an adapter (1) for connecting the anus or a perianal stoma of a user to a peripheral device, said adapter comprises a flexible adhesive plate (2) having first through going hole, a flexible tube (3) extending from a first opening (11) to a second opening (12) and a first flexible coupling plate (4) having a second through going hole, wherein the flexible tube is attached to the flexible adhesive plate in an area surrounding the first opening and the flexible tube is attached to the first flexible coupling plate in an area encircling the second opening, allowing fluid communication from the first through going hole to the second through going hole through the flexible tube, and a peripheral device (20, 60) for coupling to the adapter.

Abstract: The present invention relates to a sealing wafer (1) adapted to be arranged in a stoma receiving hole (5) of a base plate (2) comprising an attachment platform extending from an outer edge adapted to be attached to the base plate towards an inner edge defining a through-going hole (17) for receiving a stoma, the sealing wafer further comprising at least a first urging part extending transversely from the proximal surface facing towards the user during use of the attachment platform and wherein the first urging part is resilient in the direction transverse to the proximal surface. This provides a sealing wafer which is particularly suitable for use with a stoma around which the skin has an uneven curvature, such as a retracted stoma wherein the stoma has pulled back resulting in a crater-like area.