Abstract: Apparatus (2) for providing information on at least one muscle (4) in a patient (6), which apparatus (2) comprises: (i) signal providing means (8) for providing measurement-enabling signals for the muscle (4); (ii) first contact electrodes (10) for enabling the measurement-enabling signals from the signal providing means to be received by the patient (6); (iii) measurement means (12) for measuring a parameter of the muscle (4), the parameter being such that it is affected by the measurement-enabling signals, and the parameter being such that it relates to at least one electrical property that is indicative of changes in tissue impedance caused by movement of the muscle (4); and (iv) a garment (14) which is for being worn over the muscle (4) in the patient (6) and which comprises an array (16) of separate electrically conducting areas (18), and the apparatus (2) being such that the first contact electrodes (10) are able to be positioned on the garment (14) at a predetermined precise position for obtaining the

Abstract: Methods, systems, and apparatus for detecting and/or validating a detection of a state change by matching the shape of one or more of an cardiac data series, a heart rate variability data series, or at least a portion of a heart beat complex, derived from cardiac data, to an appropriate template.

Abstract: In a method and apparatus for magnetic resonance imaging, an improved saturation of magnetic resonance signals during an acquisition sequence is achieved by the acquisition sequence including at least one acquisition cycle, this acquisition cycle including a saturation pulse set composed of one or more saturation pulses, a first trigger window and a second trigger window. The first trigger window and the second trigger window are temporally delimited from one another. The first trigger window and the second trigger window are activated on the basis of a trigger signal. At least one saturation pulse of the saturation pulse set takes place during the first trigger window. Data acquisition takes place during the second trigger window.

Abstract: A location pad includes a housing having a flat surface and multiple field generators. The multiple field generators are fixed to the housing and are configured to generate respective magnetic fields having respective axes that are perpendicular to the flat surface.

Abstract: An ophthalmic surgical tool has a marker positioned at a distal portion of the ophthalmic surgical tool. The distal portion of the ophthalmic surgical tool is inserted into an eye along with the marker to perform surgeries in the eye. An imaging device captures images of the fundus of the eye including the distal portion of the ophthalmic surgical tool. An image processor processes the captured images to identify and extract the marker from the captured images. The marker has a high-contrast feature in a visible light or infrared light range or other spectral ranges. Thus, the image processor may identify and extract the marker from the captured images. Indicators may be generated based on the marker and be overlaid with the captured or processed images of the fundus and displayed to a user to indicate surgical information to the user.

Abstract: A medical reference and registration system includes a substrate configured for placement on an external surface of a patient such that the substrate conforms to and moves with the external surface of the patient. The medical reference and registration system also includes multiple integrated sensor-fiducial marker devices mounted on the substrate. Each integrated sensor-fiducial marker device includes a sensor and at least one fiducial marker coupled to the sensor. Each sensor is pre-aligned with respect to the at least one fiducial marker so that a location of each fiducial marker is known with respect to its respective sensor.

Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Abstract: A system is configured to generate a pressurized flow of gas comprised of a first gas having a partial pressure that varies in a predetermined manner. This may be used, for example, to simulate a previous and/or theoretical respiratory gas flow that was produced (or could have been produced) by a subject. The system is configured to deliver the pressurized flow of gas to a testing system configured to measure the partial pressure the first gas in flows of gas. This may provide an opportunity to determine the response of individual testing systems to various clinical circumstances.

Abstract: A health support device 10 acquires a measured ketone concentration by measuring ketones excreted from a user, acquires a target curve that expresses changes in target ketone concentration corresponds to a health objective of the user, and outputs advice information corresponding to the health objective based on a comparison result between the ketone concentration and the target curve.

Abstract: Methods and apparatus are disclosed for determining the occurrence of a closed or open apnea. Respiratory air flow from a patient is measured to give an air flow signal. The determination of an apnea is performed by applying an oscillatory pressure waveform of known frequency to a patient's airway, calculating a complex quantity representing a patient admittance (12) and comparing its value with ranges (14,16) indicative of open or closed apneas. The method distinguishes open from closed apneas even when the model used to calculate admittance is not based on details of the respiratory apparatus. In addition the patient admittance may be compared with admittance during normal breathing to avoid having to characterize the airway.

Abstract: A method of obtaining a medical image with respect to an object, setting a measurement item and a type of caliper with respect to the image, selecting a point in the medical image based on an external input, adjusting a location of the selected point, based on the type of caliper that has been set, and indicating the location-adjusted point in the medical image, is provided.

Abstract: Colpometer—device for measuring the diameter of the fundus vaginalis is an instrument for medical use that does not exist on the market and is produced from AISI 420 stainless steel for reuse after autoclave sterilization or produced from polyethylene polymer for disposable use. The device allows measurement of the diameter of the vaginal fornix to enable the medical professional to ascertain said measurement and thus to selected the size of intravaginal component to be used. It has a curved rod with a graduated scale in centimeters that is capable of measuring the distance between the distal ends of the instrument when open. The distance between the open distal ends inside the fundus vaginalis allows verification, using the centimeter scale, of the diameter of the fundus vaginalis. The ovoid distal end thereof allows insertion into the vagina without the risk of unexpected lesions occurring. It provides the appropriate dimensions of the vaginal fornix (FIG. 3-a) up to a maximum of 13 centimeters.

Abstract: A treadmill arrangement, comprising a treadmill frame and an endless belt driven by a drive and running across rollers held in the treadmill frame and whose surface serves as a walking or running surface, with handholds being mounted at upwardly extending side parts or a front part of the treadmill frame on both sides of the belt, and wherein a force sensor system with a holding force evaluation device on the output side for the time-dependent registration and optionally evaluation processing of the holding force, which is subject to the direction in space, introduced by the user into the or each handhold when using the treadmill arrangement and/or actuating means for controlling a parameter and/or a function of the treadmill arranged are assigned to at least one of the handholds.

Abstract: The present invention relates to a method for accurately and reliably determining a cardiac status of a patient. An implantable medical device, IMD, comprises a sensor arrangement adapted to sense signals related to mechanical activity of the heart and an activity level sensor arrangement adapted to sense an activity level of the patient. Further, the IMD calculates a percentage of left ventricular diastolic time (PLVDT) for a cardiac cycle corresponding to a relation between a diastolic time interval and a cardiac cycle time interval using the determined systolic and diastolic time intervals or a percentage of left ventricular systolic time (PLVST) for a cardiac cycle corresponding to a relation between a systolic interval time interval and a cardiac cycle time interval using. A cardiac status is determined based on the calculated PLVDT (or PLVST) and on an activity level of the patient.

Abstract: A system and a method for monitoring activity and posture of a person in correlation with the person's heat activity, comprising a) simultaneously detecting first linear accelerations and first angular speeds of rotation of an upper part of the person's body, second linear accelerations and second angular speeds of rotation of a lower part of the person's body, and the person's electrocardiogram signal; and b) determining the person's activity and posture from the first and second linear accelerations, the first and second angular speeds of rotation, and at least one of: i) a derivation signal, ii) heart rate and iii) a respiratory rate, of the person from the electrocardiogram signal.

Abstract: A medical device and associated method evaluate vectors of a multi-dimensional accelerometer by receiving a signal from the accelerometer for each of the vectors and determining a metric from the signal for each of the vectors during a first sensing condition and during a second sensing condition. The difference between the metrics determined for the first sensing condition and the second sensing condition for each of the vectors is determined. One of the vectors is selected, based upon the determined differences, for monitoring the patient.

Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

Abstract: Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts, on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes, on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

Abstract: Disclosed herein is a fluid conductivity sensor that can be used to obtain in-vivo measurements of conductivity of biological fluid samples, for example, to determine osmolarity. The conductivity sensor can be disposed on a substrate that is at least partially embedded within a polymeric material of a body-mountable device. The conductivity sensor can include a frame having a trench formed therein that defines a fluid sample cell. First and second electrodes can be formed on sidewalls of the trench, such that the first and second electrodes are on opposite sides of the fluid sample cell. A controller in the body-mountable device can operate the sensor by applying a voltage to the electrodes and measuring a current through a fluid occupying the fluid sample cell. The body-mountable device may indicate the current measurements wirelessly using an antenna.

Abstract: A method of monitoring the level of an analyte such as glucose in a subject comprises repeated steps of extracting a quantity of the analyte from the subject into a sample, for example using reverse iontophoresis, then measuring the concentration of the analyte with a method that depletes the analyte. Whereas known methods aim to deplete the analyte fully between extraction steps, the present method allows the concentration to build up with each cycle and measures successive changes in concentration. The higher concentrations present permit more reliable measurements to be made. The sample may be primed with an initial quantity of the analyte.

Abstract: A blood collection cartridge has a distal end, a proximal end, and defines a container interior. The cartridge includes a resealable closure sealing the distal end of the container, having a closure distal end and a closure proximal end. The cartridge also includes a cap sealing the proximal end of the container, having a cap distal end and a cap proximal end. The cartridge further includes a stopper disposed within the container interior sized relative to the container to provide sealing engagement with the sidewall of the container, the stopper having a stopper distal end and a stopper proximal end. A first fluid reservoir is bounded by the sidewall between the closure proximal end and the stopper distal end, and a second fluid reservoir is bounded by the sidewall between the cap distal end and the stopper proximal end. An anticoagulant is disposed within the first fluid reservoir.

Abstract: On-body analyte monitoring devices configured for uncompressed and compressed configurations and methods of using the analyte monitoring devices are disclosed. The devices comprise a collapsible housing, wherein upon desired placement and user application of force to the housing converts the analyte monitoring device from an uncompressed configuration to a low-profile compressed state while guiding an analyte sensor through the skin and into contact with bodily fluid to measure and analyte level therein. Also provided are systems and kits.

Abstract: Provided are systems and methods for minimally invasive arterial blood gas measurements. Blood samples are collected using capillary microstructures that minimize patient discomfort and collect samples in a manner such that the samples are not exposed to an environment outside of the sample collection portion. One or more characteristics of the blood sample are then calculated and used to derive one or more arterial blood gas measurements for the sample.

Abstract: The present disclosure is directed to a needle assembly for drawing blood. The needle assembly can be a standalone or part of an over-the-needle medical device, such as an intravenous catheter. A blood collection device is attached directly or indirectly to the needle hub of the needle assembly and/or to a catheter hub, such as through a Y-site or adaptor connected to a tubing that is connected to the catheter hub. The needle is configured to access the vascular system to draw blood, which then passes to the blood collection device via the needle lumen, which has a tip having a discontinuity opening, an opening with a movable stem, or a shaft element with a lumen.

Abstract: A collection device holder is designed to hold a plurality of blood collection tubes. The holder includes a support member and a plurality of holding portions. Each of the plurality of holding portions is configured to hold a blood collection tube with respect to the support member such that inlets of the plurality of blood collection tubes are arranged in a predetermined pattern with respect to one another. In a preferred aspect, the predetermined pattern corresponds to a predetermined pattern of a plurality of spaced sharpened tips of a lancet device.

Abstract: According to the present disclosure, a state estimation device estimating a state of a monitoring target based on an involuntary eye movement of an eyeball of the monitoring target is provided. The state estimation device in the present disclosure includes a microsaccade information acquisition portion obtaining microsaccade information that includes a state of variation of a gaze angle when a microsaccade of the involuntary eye movement occurs, and a state estimation portion estimating the state of the monitoring target based on the microsaccade information.

Abstract: An in-situ physiologic monitor for a body is disclosed. The in-situ physiologic monitor comprises an electronic monitoring module, wherein the electronic monitoring module is capable of logging an electronic monitoring module sensed parameter; and a body attachment component, wherein the body attachment component attaches the electronic monitoring module to the body.

Abstract: A pressure wound prevention system operable to prompt at least one caregiver to reposition a subject at risk of developing a pressure wound. The system includes a pressure-detection surface comprising a plurality of pressure sensors configured to monitor pressure exerted upon the pressure-detection surface by the subject as well as orientation sensors configured to monitor an angle of the pressure-detection surface. A processor is operable to interpret and analyze data from the sensors and to provide indications to a caregiver when the subject requires repositioning.

Abstract: A three-dimensional ultrasonic imaging system comprises a vertical stand (1), a computer (3), as well as an ultrasound scanner, a space sensor, and a first display (8) connected to the computer (3) respectively. The ultrasound scanner is provided with an ultrasonic probe (17). The three-dimensional ultrasonic imaging system further comprises a gravity balance board (2) mounted under the vertical stand (1) and connected to the computer (3), a second display (4) connected to the computer (3), and a support structure for supporting a patient. The support structure is mounted on an upper part of the vertical stand (1). The gravity balance board (2) is used to measure feet pressure distribution data information of the patient, and send the feet pressure distribution data information to the computer (3).

Abstract: An approach for providing diagnostic information regarding one or more impacts sustained by one or more users while the one or more users are participating in a team activity is described. A diagnostic platform detects one or more impacts sustained by a user, wherein the user is part of a team with one or more other users engaged in a team activity. The diagnostic platform generates a recommendation for a level of participation of the user, the one or more other users, or a combination thereof in the team activity based on the one or more impacts, a severity level of the one or more impacts, or a combination thereof. The diagnostic platform further presents the recommendation, a representation of the severity level, a representation of the level of participation, or a combination thereof in a user interface.

Abstract: An approach for monitoring a sleeping subject includes receiving an input for specifying an attachment position of a monitoring device attached to a subject, calibrating a resting positioning of the subject based on the attachment position, analyzing sensor information collected from the monitoring device to determine a movement of the subject into a potentially dangerous position with respect to the calibrated resting position, wherein the monitoring device includes an array of sensors including an accelerometer, one or more biometric sensors, or a combination thereof.

Abstract: A method and system of physiological monitoring, includes measuring a quantity relating to a first subject with a first sensor positioned in or in proximity of the first subject and configured to provide a first signal, measuring a quantity relating to a second subject with a second sensor positioned in or in proximity of the second subject and configured to provide a second signal, and analyzing the first and the second signal and the interrelation of the first and second signal in order to determine at least one event relating to the first and/or the second subject.

Abstract: The present Invention (the “Invention”) relates to an apparatus to detect, assess and end occurrences of snoring, sleep apnea events and hypopnea episodes, in a manner that will decrease or eliminate hypoxia, hypercapnia and the disturbance of cardiac and pulmonary hemodynamics, and give users of the apparatus a report of their critical sleep data each morning

Abstract: A catheter system for controlled sympathectomy procedures is disclosed. A catheter system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed.

Abstract: This disclosure provides devices, systems, and methods for detecting physiological parameters, and for communicating information related to the detected physiological parameters to the user, the user's caregiver, and medical personnel. For example, some systems described herein can be configured to detect a user's hypoglycemic event, and to thereafter alert the user, caregivers, and medical personnel to the occurrence of the hypoglycemic event.

Abstract: A biometric information detecting apparatus includes: a band unit; a case unit that is attached to the band unit; a sensor unit that is provided in the case unit; and a processing unit that is provided in the case unit and detects biometric information based on a detection signal from the sensor unit. The band unit includes an inner surface having a first curved surface shape on a side thereof that faces a test object when the biometric information detecting apparatus is mounted, and the case unit includes an outer surface having a second curved surface shape that faces the inner surface of the band unit.

Abstract: The present invention provides a system for monitoring a physiological parameter of players engaged in a sporting activity. The system includes a plurality of reporting units, a controller, and a signaling device. The reporting unit has an arrangement of sensing devices that measure the physiological parameter of an individual player and generate parameter data. The controller receives the parameter data transmitted from each reporting unit and then processes the parameter data to calculate a parameter result. When the parameter result exceeds a predetermined value, the controller communicates with a signaling device that provides an alert to sideline personnel to monitor the player(s) in question. The system also includes a remote storage device for holding historical data collected by the system which permits subsequent analysis.

Abstract: Measurement device for measuring a bio-impedance and/or a bio-potential of a human or animal body and adapted to be worn on the body, including: at least two electrode sensors. Each of the at least two electrode sensors includes a first electrical contact configured to be in electrical contact with the skin of the body when the system is worn, and a second electrical contact. A single electrical connector electrically connects the at least two electrode sensors with each other via the second electrical contact. An active device is configured to cooperate with a subset of the at least two electrode sensors such that the potential of the electrical connector is substantially equal to a projected potential determined from the potential of the first electrical contact of each electrode sensor of the subset when the measurement device is worn.

Abstract: An MRI antenna array including a housing and a substrate, antenna elements and circuitry encapsulated by the housing. The housing, antenna elements, and substrate are flexible to allow the housing to distort in three dimensions to closely conform to contours of a patient. The antenna elements are mounted to the substrate in a manner that permits each element to maintain a desired resonance when the housing is distorted in three dimensions. The circuitry is electrically coupled with the antenna elements to maintain tuning and isolation of the elements when the housing is distorted in three dimensions. The housing, antenna elements, and substrate may be elastic to allow the housing to be worn by a plurality of different sized patients so that the housing is in close contact with the patient and conforms to contours of the patient.

Abstract: A thermochromic fabric utilizing cholesteric liquid crystals includes a fabric material or garment formed therefrom. The liquid crystal material is patterned with a plurality of different liquid crystal formulations, whereby each formulation has high thermal sensitivity over a narrow temperature range. As a result, the aggregate pattern of liquid crystal material formed on the thermochromic fabric allows the thermochromic fabric to have high thermal sensitivity over a broad temperature range. As such, the fabric or garment may be worn on specific body parts of a patient, such as his or her feet, to assist in making a medical diagnosis.

Abstract: A method may involve providing a conductive pattern on a bio-compatible layer. The conductive pattern may include a first conductive layer that comprises a first metal and a second conductive layer that comprises a second metal. The second conductive layer may be over the first conductive layer, and the first metal may be more malleable than the second metal. The method may also include mounting an electrical component to the conductive pattern to provide an electrochemical sensor. The electrochemical sensor may be configured for use in a body-mountable device.

Abstract: A transducer holder assembly for attachment to a patient includes a support member with a contact surface and an oppositely disposed connection surface. The support member includes at least one electrode disposed on the contact surface. A first mating member is coupled to the connection surface. A housing is configured to receive and hold at least a portion of a transducer. The housing includes a second mating member configured to releasably mate with the first mating member via a snap-fit mechanism.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: A biopotential signal acquisition system including an analogue readout unit configured to receive an analogue biopotential signal, which may be acquired from at least one electrode attached to a body; and to extract an analogue measured biopotential signal and an analogue reference signal. The system also includes an ADC unit configured to provide a digital version of the analogue measured biopotential signal and the analogue reference signal, a digital filter unit configured to calculate a digital motion artifact estimate based on the digital version of the measured biopotential signal and the reference signal. The system further comprises a reference signal processing unit configured to convert the reference signal into a new reference signal being provided to the digital filter unit based on the correlation between the measured biopotential signal and the reference signal.

Abstract: A lesion determination apparatus includes: a number-of-images acquiring unit configured to acquire and record, on occurrence of a direction change that is either a first state in which a second operation instruction is received immediately after receipt of a first operation instruction or a second state in which the first operation instruction is received immediately after a receipt of the second operation instruction, a number of one-directionally viewed images that is either a number of tomography images continuously viewed in response to continuous first operation instructions including the first operation instruction in the first state or a number of tomography images continuously viewed in response to continuous second operation instructions including the second operation instruction in the second state; and a locality determining unit configured to determine whether the object part is a focal lesion or a diffuse lesion based on a change in the number of one-directionally viewed images.

Abstract: The application discloses a method of determining the severity of symptoms in a patient comprising (i) producing a triage score, such as an early warning score (EWS) modified early warning score (MEWS), paediatric early warning score (PEWS), NHS early warning score (NEWS), simple clinical score (SCS), rapid emergency score (REMS) or mortality in emergency department sepsis score for the patient, (ii) measuring an amount of free light chains (FLC), preferably combined free light chains (cFLC), in a sample from the patient, and (iii) using the triage score and the amount of FLC measured to assess the severity of symptoms in the patient. This also allows patients to be triaged to provide better treatment of them.

Abstract: A biological information measuring device includes a biological-information detecting unit configured to detect biological information of a human body on which the biological information measuring device is worn, an acceleration detecting unit configured to detect acceleration, a mode setting unit configured to set, among a plurality of operation modes set on the basis of a change in the detected acceleration, an operation mode corresponding to a change pattern of the acceleration, and an executing unit configured to execute processing corresponding to the set operation mode.

Abstract: A physiological monitoring system may use photonic signals to determine physiological parameters. The system may vary parameters of a light drive signal used to generate the photonic signal from a light source such that power consumption is reduced or optimized. Parameters may include light intensity, firing rate, duty cycle, other suitable parameters, or any combination thereof. In some embodiments, the system may use information from a first light source to generate a light drive signal for a second light source. In some embodiments, the system may vary parameters in a way substantially synchronous with physiological pulses, for example, cardiac pulses. In some embodiments, the system may vary parameters in response to an external trigger.

Abstract: A medical monitor is provided. The medical monitor may include a plurality of sheets and a power source electrically connected in series with an alarm and an open circuit. The plurality of sheets may include a distal side and a proximal side. The open circuit may be sandwiched between distal sides of adjacent sheets. A user may mount either proximal side to a bleed site on a patient where bleeding can occur, for example, entry points for intravenous applications. The plurality of sheets may allow blood to flow from the bleed site through the proximal side and through distal side so that the blood may close the open circuit, so that the alarm is powered.

Abstract: The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates optical characteristics of light transmitted into a patient to ascertain physiological signals, such as pulsatile changes in general blood volume proximate a light detector module. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.