Abstract: A method of deploying an ocular implant into Schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.

Abstract: A prosthesis capable of being worn on the eye of a wearer having a convex surface and a concave surface. The prosthesis has an aperture widening zone for widening the natural palpebral fissure of the wearer's eye. The aperture widening zone may include a surface feature having an outer slope, an inner slope, and a maximum added thickness delta located between the outer slope and the inner slope. At least a portion of the surface feature may be designed in using one or more spline curve functions. Methods for designing and manufacturing prostheses having a surface feature at least partially designed using one or more spline curve functions are also provided.

Abstract: An intraocular shunt can be placed into a human eye using a hollow shaft having a distal tip with a bevel. The hollow shaft can be advanced through the anterior chamber while the hollow shaft holds the intraocular shunt. The sclera can be penetrated with the beveled distal tip until all of the bevel is positioned distal to a distal wall of the sclera. The shunt can be advanced at least partially from the hollow shaft into a drainage space of lower pressure than the anterior chamber. The hollow shaft can be withdrawn from the eye, leaving the shunt extending from the anterior chamber completely through the sclera to the drainage space.

Abstract: A goggle structure includes a protective soft pad, a frame, and a subsidiary lens frame. Convex portions are formed on upper and lower sides of the subsidiary lens frame and inserted into slots disposed at the frame, respectively. Hook portions are formed on upper and lower sides of the frame and extend backward. By inserting the frame into a receiving space disposed at the protective soft pad, the hook portions press against the periphery of the receiving space. Pressing portions and carrying portions are formed on upper and lower portions at the middle segment of the frame and adapted to hold the protective soft pad. The bottom of the subsidiary lens frame straddles the pressing portions and carrying portions. Branch portions extend from two outer sides of the frame to press against a concave portion of the protective soft pad. Hence, related components are engaged with each other.

Abstract: A braided goggle strap for use with a pair of swimming goggles includes a plurality of bands that are braided together to form a generally flat, braided goggle strap. Each of the plurality of bands includes an elastic material that is protected by a resilient fabric material to provide superior mechanical properties that results in even stress distribution and minimal sinusoidal stress when worn by a user. The composite reinforcement of the braided goggle strap also provides added comfort. The braided goggle strap includes a biased fastener for adjustably attaching the braided strap onto a user's head, is easily attachable to a pair of swimming goggles by simply threading the braided strap through the small apertures provided on the swimming goggles, and comes in a variety of different colors.

Abstract: A goggle lens positioning structure includes a protective soft pad, a frame, and a lens. The lens and the frame are coupled together by following the steps below. Pressing portions and carrying portions disposed at upper and lower sides of the frame and extending forward are inserted into concave portions concavely disposed at corresponding portions of the lens. After penetrating holes disposed at corresponding portions of the lens, branch portions extending from two outer sides of the frame leave a hole at one end of a fastening unit to restrict movement. The frame is received in the receiving space of the protective soft pad to effectuate engagement therebetween. Hence, the lens and the frame can be quickly put together and easily separated.

Abstract: A goggle adapted for utilizing a plurality of batteries to perform a powered function for the goggle comprising: a lens retained in a goggle body, strap extension members connected to the goggle body, each extension member defining therein a cavity having a contact for retaining a battery pod, each battery pod having a chemical cell battery therein, for powering the goggle to enable one or more of heating the goggle lens, video capture, GPS, stereo sound or other electronic function of the goggle. The cavities are symmetrical about a z-axis and the batteries for the system are interchangeable such that any battery pod may be flipped about the z-axis and retained in any battery cavity. The goggle is further comprised of a strap portion, either attached to the extension members or integral therewith, for retaining the goggle on a user's head or helmet.

Abstract: A tympanostomy tube applicator has a hand-held housing and a stem extending from the housing and having a shape arranged for engagement in the ear canal. A tympanostomy tube inserter has a user actuator, a rod having a tip to pierce a patient's tympanic membrane and to support a tympanostomy tube through the membrane where it is pierced. The inserter inserts a collapsed tympanostomy tube through the membrane and expands the tube in situ to provide a distal flange in the tympanostomy tube. A myrongotomy tip expands the tube to a final state having a distal flange as it is retracted.

Abstract: A wound dressing including a hydrophilic layer and a hydrophobic layer is described. The hydrophilic layer absorbs exudate from a wound and the hydrophobic layer absorbs the exudate from the hydrophilic layer and traps the exudate. Because the hydrophilic layer is used adjacent to the wound, the exudate is readily absorbed thereby reducing the risk of maceration and infection of the wound tissue by the exudate. The hydrophobic layer receives the absorbed exudate from the hydrophilic layer and traps the exudate through an interaction that in turn prevents lateral diffusion of the exudate through the bandage to healthy portions of the skin. The hydrophilic and hydrophobic layers are fabricated from polymer fibers that can be spun to include components that facilitate wound healing, such as poly(hexamethylene biguanide) and/or hyaluronic acid.

Abstract: The invention is a class of medical bandages that are effective for use in the treatment of various types of tissue burns, such as burns due to heat, chemicals, or sun exposure. The inventive bandages are comprised of a thin metal substrate in combination with a heat-sink. The inventive bandages incorporate a metal substrate (such as aluminum) having a burn-facing side for direct contact with the burn to draw heat away from the burn by conduction, and a heat-sink facing side opposite the burn-facing side for contact with a hydrogel to draw heat away from the metal layer by conduction. The thin aluminum layer and associated hydrogel heat-sink ensures flexibility and effective heat-transfer characteristics to rapidly cool a burn wound.

Abstract: A wound barrier pad is provided having a housing with a truncated conical shape. A base plate with an opening is disposed in the housing, and the housing is filled with a fluid or padding. The wound barrier pad may be incorporated into a garment. In another embodiment the wound barrier pad includes a ring and an adhesive such that the wound barrier pad may be directly adhered to the patient, thus eliminating the need for the garment. In another embodiment there is a wound barrier device having a pad assembly and an anti-sheer member. In another preferred embodiment there is a sacral wound barrier pad device comprising a sacral wound barrier pad assembly having teardrop shape and first and second pads with at least one insert disposed between the first and second pads. A contact layer is joined to the second sacral pad.

Abstract: Varying sizes of raised surfaces that are located outside an area affected by a blister, cut, wound or stitches that will absorb the pressure created from an outside force and eliminate pain from the pressure of said source.

Abstract: A wound dressing comprising a base film layer which is made of polymer and have a grid pattern on one surface of the substrate layer is provided. A method of making the wound dressing comprising the steps of coating a polymer solution on a patterned liner and drying the polymer solution is also provided.

Abstract: A device is described that is configured to protect a joint of a wearer. The device includes a device cover structure having an interior surface of phase change fabric material that is placed toward the wearer's joint and an exterior surface of unbroken loop fabric that comes in direct contact with external objects such as a mattress and/or other parts of the users body or that of another person while in their preferred position for sleeping, resting or reclining. The device also includes flexible elastic wraps for securing the device cover. The Device furthermore includes one or more protective pads inserted into a pocket formed in the device cover structure.

Abstract: The present disclosure relates to methods and apparatuses sensing emitted light caused by fluorescence of adhesive to determine characteristics of absorbent structures during the manufacture of absorbent articles. Some absorbent articles may have absorbent structures that include an absorbent core disposed between a topsheet and a backsheet. And one or more of the absorbent structure components may be assembled with adhesive that fluoresces when excited by ultraviolet light. Aspects of the present methods relate to an inspection system that may be configured to interact with, monitor, and/or control a converting line. The inspection system may include a radiation source that illuminates a surface of an absorbent structure with ultraviolet light. A sensor may be adapted to receive light caused by fluorescence of the adhesive while being irradiated with the ultraviolet light. In turn, the inspection system may determine characteristics of the absorbent structure based on the detected emitted light.

Abstract: [Problem] To provide a disposable diaper which is comfortable to wear. [Solution] This disposable diaper comprises a top sheet (1), a back sheet (2), an absorber (3) and a stretchable sheet (4). The stretchable sheet (4) is composed by having a base material sheet (41) sandwich multiple elastic stretchable members (42) disposed therein in an extended state, said multiple elastic stretchable members (42) being disposed along the width direction of the disposable diaper and spaced apart at intervals in the longitudinal direction. When viewed in the width direction, the stretchable sheet (4) has an overlapping portion (43) which includes a region that overlaps with a part of the absorber (3). In the overlapping portion (43), the multiple elastic stretchable members (42) are disposed continuously along the width direction.

Abstract: Absorbent, launderable garments and undergarments for incontinent or other persons likely to discharge fluids from time to time are supplied in many styles and capacities. All include a shaped absorbent pouch assembly, having an inner conformable and permeable layer in contact with the skin and an absorbent cotton layer sealed under a gas-permeable yet waterproof and stretchable textile. The pouch is positioned by a set of elastic strips or sheet elastic fabric; each set being visually similar to a style of regular underwear. A preferred waterproofing treatment uses an emulsion of fluoroalkyl acrylate permeated into a knitted or woven textile. In higher capacity versions the entire garment is waterproofed.

Abstract: The present invention provides a composite sheet material in which a three-dimensional sheet material and a flat sheet material are firmly joined to each other and which is excellent in ventilation and the like, soft, and good in touch. In the composite sheet material, a three-dimensional sheet material having a large number of protruding portions formed thereon and a flat sheet material not having such protruding portions are layered on each other and joined. The three-dimensional sheet material is joined to the flat sheet material at joining parts apart from protruding portions A plurality of joining parts are formed around each protruding portion in such a manner as to surround the protruding portion. The area of the joining part is less than of that of a base surrounded by the protruding portions. Some of the joining parts are provided with a through hole penetrating the composite sheet material.

Abstract: A wearable tube apparatus for placement over the genitals of a male subject to absorb urine released from the penis and wick moisture from the genitals, thereby preventing the subject from soiling himself The wearable tube apparatus comprises an elongated tube body defined by a flexible, hollow tubular member with a fluid resistant outer layer and a fluid absorbent inner layer. The flexible tube body includes a closeable opening on its superior region and an elastic opening on its proximal end and is structured to taper upward towards the proximal end. The closeable opening enables a caregiver or the user to reach into the hollow area of the elongated tube body so adjust the genitals or so the interior absorbent layer can be touched to check for moisture without requiring the removal of the wearable tube apparatus.

Abstract: The present invention relates to an odour control material consisting of a water-insoluble particulate odour control agent and a thermoplastic water-soluble carrier matrix encapsulating the odour control agent. The carrier matrix dissolves when in contact with an aqueous solution, such as urine and the odour control material is obtained by means of thermoforming. The invention relates also to a method for the preparation of the odour control material and the use of the odour control material in absorbent products. The present odour control material minimizes dusting problems caused by particulate odour control agents in production processes.

Abstract: Disclosed is a method and apparatus to protect a limb having a wound or condition requiring dryness from moisture. The method of applying a protective covering for a wound or condition requiring dryness comprising the steps of positioning a waterproof polyester fabric sock around an appendage having a gasket secured to an open end of the sock for sealing the sock to an appendage.

Abstract: A mattress can be adapted to an integrated bed that includes a main bed unit, and a wheelchair unit that is separable from the main bed unit and has a wheelchair back bottom, a wheelchair hip bottom and a wheelchair foot bottom. The mattress includes a first protrusion configured to be fastened to a back-section hole in the wheelchair back bottom, a fastener configured to be fastened to the wheelchair hip bottom, and a second protrusion configured to be fastened to a foot-section hole in the wheelchair foot bottom.

Abstract: An electromagnetic anti-tipping device uses electromagnets to steady users and prevent falls by persons with impaired mobility and balance. The device's steadying effect is accomplished by magnetically attracting the legs and/or wheels of balance and mobility assisting apparatus (“balance and mobility aid(s)”) to a stationary surface such as a floor which is made of or covered with a magnetically responsive material. In one embodiment, the device's electromagnet attraction to the floor or other stationary surface is actuated when the operator of the device triggers the device's mechanism or sensor by grip or touch. Once actuated, and until deactivation by the user, the device's electromagnet(s) secure the legs or wheels of the balance and mobility aid to the magnetically responsive floor or other stationary surface. The electromagnets are battery-powered.

Abstract: A wheelchair safety device transfers the weight of an entering or exiting user into a brake and stop against the rear wheel and floor, ensuring stability during the transfer. The device may be installed on one or both of the rear wheels of the wheelchair, and provides a handle which will bear the user's full weight with complete stability during the transfer. When not in use, the brake is disengaged, the floor stop is fully retracted to enable complete maneuverability of the wheelchair, and the handle also retracts.

Abstract: Equipment for raising of a lying person. The equipment comprises: a seat (1), a backrest (2), which from a first position can be passed to a second position behind the back of the person, and a chassis (3) with an upper end to which the seat is connected and a lowermost end adapted to rest on a surface such as a floor. The equipment is to be placed on the surface positioned to the person such that the seat is placed under the behind of the person and from this first position the equipment with the person can be passed to a second position in which the chassis with its lower end rests on the surface such that the seat and backrest is raised relative to the surface e.g. to take a chair-like posture or a catapult position i.e. an upright position in which the person will be assisted to a standing position.

Abstract: A lifting column includes first and second lifting column components, one slidably receivable in the other, each having mutually facing guide surfaces. The first lifting column component has first and second openings in its guide surface, and first and second guide components mounted in these openings. Each of the guide components includes an attachment structure that projects into one of the first and second openings and a substantially planar guide section connected to the attachment structure that overlies a guide surface of the first lifting component and that is configured to abut on the guide surface of the second lifting column component. The first and second guide components are configured such that they are in contact with each other when the attachment structures are mounted the openings.

Abstract: An articulable sleep system has a first head section, a second head section, and a joined leg section that are each separable articulable. A head motor system includes a first and second head motors operably connected to the first and second head sections. A leg motor system includes first and second leg motors operably connected to the joined leg section. A first user controlling device is hard wired to each of the first head motor, the first leg motor, and the second leg motor. A second user controlling device hard wired to each of the second head motor, the first leg motor, and the second leg motor.

Abstract: Patient support apparatuses, such as beds, cots, stretchers, recliners, operating tables, and the like include wireless mesh network transceivers that enable them to communicate with each other, and other devices, via mesh networks and/or ad hoc networks. One or more additional wireless transceivers are included, such as WiFi transceivers, that enable direct communication with a healthcare facility network, such as an Ethernet. The mesh network communication between patient support apparatuses and other devices is used for any one or more of: extending the communication range of the existing IT infrastructure, efficiently routing data to the healthcare facility network, determining location of the patient support apparatuses and devices, transporting patient data from one patient support to the next as the patient moves, and for other aspects.

Abstract: Person support apparatuses having exercise features are disclosed herein. In various embodiments, a person support apparatus includes a support surface, a footboard, a sensor, and a passive resistance mechanism. The support surface has a foot end and a head end, and the footboard is located near the foot end of the support surface, extending above the support surface. The footboard may include a pressure surface positioned to receive a pressing force. The footboard is freely slidable from an extended position to a retracted position with respect to the foot end of the support surface. The sensor provides a signal indicative of a magnitude of the pressing force incident on the pressure surface of the footboard. The passive resistance mechanism is coupled to the footboard, and resists a motion of the footboard to the extended position.

Abstract: Underbody supports and related methods for supporting and restricting a sliding motion of a patient on a table. Certain embodiments of the underbody support may include two side walls, two end walls, a base layer, a compressible material layer opposite the base layer. The compressible material layer may be bonded to the two side walls and the two end walls about a perimeter of the compressible material layer to form a box-like structure that surrounds one or more inflatable chambers. The underbody support may further include one or more friction enhancing elements that are arranged to be interposed between the upper surface of the compressible material layer and the patient when the patient is being supported on the underbody support to prevent sliding of the patient.

Abstract: Chiropractic table that allows conservation of the natural curves of the spine of a patient using thereof, comprising a continuous curved surface having a concave section at its central portion on the convex side of said curved surface defining first and second convex sections, wherein the ends of the curved surface are in contact with the ends of a frame composed of a plurality of longitudinal straight bar pairs, parallel to each other and which are transversely joined by a plurality of main transverse bars to said longitudinal straight bars, wherein further the first convex section has a greater height than the second convex section with respect to the plane defined by the plurality of longitudinal straight bars and the plurality of main transverse bars.

Abstract: A system for securing and manipulating a patient during a medical procedure comprises a support assembly coupled to a bed and configured to support a patient's leg. In addition the system comprises a rail coupled to the support assembly. The rail has a longitudinal axis, a first end, and a second end opposite the first end. In addition, the system comprises a perineal post movably mounted to the rail and oriented in a generally vertical direction. The post assembly is configured to move axially along the rail between a first position and a second position.

Abstract: Apparatus and methods related to an underbody support for supporting a body of a being, such as during surgery to prevent contact pressure injuries. In certain embodiments, the underbody support may include one or more inflatable chambers enclosing a volume. At least one of the inflatable chambers may include one or more compression sensitive switches for monitoring the volume of the inflatable chamber, and the one or more compression sensitive switches may be located within the inflatable chamber. In some embodiments the one or more compression sensitive switches are sized to close when the said inflatable chamber is deflated to a desired residual volume.

Abstract: A patient positioning table has a transfer plate that is reversibly transferable from the patient positioning table to a table associated with an imaging modality, and a headrest-forming extension component having a fastening section and a supporting section is provided, which can be detachably fastened to fastening devices provided on the transfer plate in exchange for a framework-like head immobilizing fixture, which can be detachably fastened to the same fastening devices.

Abstract: A combination casket and casket display comprises a reduced height casket shell adapted to receive the remains of a deceased and having a pair of side walls, a pair of end walls, and a bottom wall, the side walls and end walls having lower edges, the bottom wall extending below the lower edges of the side walls and end walls, a casket lid closable on the reduced height casket shell, and a casket display base having a pair of side walls and a pair of end walls, the side walls and end walls having upper edges. The reduced height casket shell is supported by the casket display base such that the lower edges of the side walls and end walls of the reduced height casket shell are at about the same height as the upper edges of the side walls and end walls of the casket display base, and the bottom wall of the reduced height casket shell extends below the upper edges of the side walls and end walls of the casket display base so as to nest within the casket display base.

Abstract: A first call pouch includes an inner layer forming a compartment comprising at least one sidewall, a bottom wall and a top having a zippered opening. The inner layer is water resistant/proof/sealed to contain fluids. The inner layer further including one or more pockets formed therein for storage of related items including gloves. The zippered opening is a bi-directional zipper extending substantially the entire length of the bag. An outer layer encapsulates the inner layer. The outer layer includes at least one outer sidewall, an outer bottom wall, and an outer top wall that shares the zippered opening with the inner layer whereby opening of the bi-directional zipper provides access to the inner compartment. Further, the outer bottom has a pocket adapted to receive a pad. And the outer layer top wall has at least one pocket.

Abstract: A therapeutic massage chair is reclinable between a horizontal and inclined position. The chair includes an upper back support member and a lower support member that is axially movable along a support frame and is also rotatable about an axis which is perpendicular to the plane of the upper back support member. Electric linear actuators are provided to both axially move and oscillate the lower body support member.

Abstract: A rocker for releasing leg muscle cramps is described in the present application. The rocker is a device that mechanically rocks the legs of a user for their release from muscle cramps. While releasing the leg muscle cramps, the user is lies on his back; his legs are attached to the rocker, which is capable of rocking the legs in various rocking movement patterns. These movements can include movement components in any possible direction, combined with movement components such as horizontal vibration, which is practically parallel to the direction in which the user is lying, a horizontal vibration component which is perpendicular to the direction of the previous movement component, and a vertical movement component. The user can choose the frequency of vibration of these movement components, and the result is vibration with a complex spatial movement.

Abstract: The Navigator is multiple degree of freedom neuro rehabilitation system. The Navigator simultaneously exercises both pronation and supination of the wrist (rotation) and flexion and extension of the fingers (grasp and release) for rehabilitation and monitoring of patients with motor control deficits due to a neurological ailment, such as stroke. In addition, the Navigator provides a visual, interactive environment for performing therapeutic exercises. The interactive environment provides motivation to the patient and can provide real-time feedback to the patient about the quality of the movements being performed.

Abstract: A device for applying traction to the cervical vertebrae to reduce fracture dislocation of the cervical spine, said device including: a support surface adapted to support a patient lying upon his or her back; a load transmitting means adapted to be connected at one end to a patient under treatment and lying upon said support surface; the other end of said load transmitting means being adapted to be connected to a load applying means; said load applying means being movable along a regular or irregular curve to any of a range of predetermined positions between a first position which places the patient's cervical spine in flexion and a second position which places the patient's cervical spine in extension.

Abstract: A method for therapeutically affecting the circulation of blood in a person in combination with or with medication to treat a medical condition includes the steps of administering a composition for treating a circulatory condition, providing a source of high pressure air in fluid communication with a plurality of air pressure actuated valves, each of the valves mounted on, and in fluid communication with, an inflatable bladder disposed within a cuff removably attached about at least one of the feet, calves, thighs, buttocks of the person; providing a source of low pressure air in fluid communication with said plurality of valves, wherein a constant pressure is exerted against said valves; and controlling inflation of said bladders in a predetermined sequence, magnitude of inflation pressure and period of time during a cardiac cycle of the person and as a function of said person's physiological reaction to said composition.

Abstract: A vibrating sole device, comprising a vibration unit located within a cavity in a sole, comprising a unitary housing having an interior portion and a heel portion, a vibrator located at the interior portion of the housing, a power supply located at the interior portion of the housing in electrical connection with the vibrator, an actuator for said vibrator in the housing, a status indicator located on the heel portion of the housing, and a power supply port located on the heel portion of the housing.

Abstract: A necklace for activating the thymus gland has a vibration mechanism with a vibration motor, a power source and an on/off button.

Abstract: A method for treating patients with sensor agnosia is described that uses a gaming system with a specialised two handed game controller that can provide isolated haptic feedback to the patient's hand that has the greatest sensory agnosia. The controller is designed to be easy to use for patients with limited dexterity and requires the user to use both hands to control the controller. The gaming system provides a range of interactive computer games that provide contextually relevant haptic feedback of varying durations and intensities. Haptic feedback is provided in response to events in a game, and whilst the controller requires two hands, each hand is vibrationally isolated so that haptic feedback is only provided to the desired hand. The system logs usage statistics of the patient and these can be sent back to a clinician for analysis. The system and controller is particularly suitable for children with Cerebral Palsy, but may be used to treat patients with sensory agnosia due to range of conditions.

Abstract: A medical container is formed by blow molding, and subjected to the steam sterilization. The medical container includes: an innermost layer made of a cyclic polyolefin resin; a gas barrier layer located at a position external to the innermost layer and made of an ethylene-vinyl alcohol copolymer resin or the like; and an adhesive layer jointing at least the gas barrier layer to the innermost layer. An adhesive used in the adhesive layer contains maleic anhydride modified polypropylene and styrene elastomer.

Abstract: A device is disclosed for reconstitution and delivery of an injectable pharmaceutical. A diluent is provided in a pressurized reservoir, while separately a syringe with a needle contains a pharmaceutical such as a lyophilized drug. When the pressurized reservoir is coupled to the interior of the syringe, such as by piercing the pressurized reservoir with the needle, the pressurized reservoir forces the diluent into the syringe where the diluent can mix with and reconstitute the pharmaceutical. A variety of techniques are disclosed for pressurizing the reservoir and fluidly coupling the reservoir with the syringe. The techniques disclosed herein may, for example, be adapted for use with a conventional syringe and needle.

Abstract: There is provided a drug container storage device used for performing sucking of a drug contained in a drug container using a syringe, the syringe having a passage portion through which a liquid is sucked in and discharged, and the drug container having a lid portion that can be penetrated by the passage portion. The drug container storage device has a main body portion including a closed space configured to accommodate the drug container and a first opening; and an elastic sealing portion configured to hermetically seal the first opening of the main body portion and that can be penetrated by the passage portion of the syringe. The main body portion is configured to accommodate the drug container such that a space is formed between the lid portion of the accommodated drug container and the elastic sealing portion.

Abstract: An article is described including an article surface and a coating set comprising an optional tie coating or layer, a barrier coating or layer, and a pH protective layer. The respective coatings or layers can be applied by chemical vapor deposition of a polysiloxane or polysilazane precursor in the presence of oxygen. Examples of such an article are a prefilled thermoplastic syringe or thermoplastic pharmaceutical vial with a coated interior portion containing a pharmaceutical preparation or other fluid with a pH of 4 to 8, alternatively 5 to 9. The barrier coating or layer prevents oxygen from penetrating into the thermoplastic syringe or vial. The tie coating or layer, if present, and the pH protective coating or layer protect the barrier layer from the contents of the syringe or vial.

Abstract: A cap for use in enteral feeding from a container. The cap includes a base and an insert cutter. The base has a top surface, a bottom surface, and an outer ring. The top surface has a protruding port suitable for insertion of a spike connector. The protruding port defines a spike insertion chamber extending from a spike connector insert aperture to a spike connector outlet aperture. The outer ring is configured for attachment to a container having a mouth. The insert cutter has a first end portion attached to the bottom surface of the base and about an edge of the spike connector outlet aperture and a second end portion extending over at least a portion of the spike connector outlet aperture. The insert cutter is capable of flexing in an insertion direction of a spike connector inserted through the spike insertion chamber.

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.