Abstract: Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.

Abstract: Surgical instruments and methods for applying variable compression to tissue are described herein and can have particular utility when cutting and sealing tissue. In one embodiment, a surgical instrument end effector is described that includes first and second jaw members movable relative to one another between an open position and a closed position to clamp tissue therebetween. The end effector can include a compression member configured to translate along the end effector to move the first and second jaw members and apply a variable compression force to the tissue. The variable compression force can have different profiles along the length of the end effector, including, for example, a continuously increasing profile or a profile that alternates between different values. The provided variable compression can reduce the force required to actuate the surgical instrument and increase the quality of a tissue seal formed thereby.

Abstract: An improved motorized burr instrument for operation on tissue at a desired surgical site surrounding by fluid, the motorized burr instrument being operable with a variable speed motor at a rotary drive coupler with a hub extending therefrom, an outer sheath housing a rotating member extending between the rotary drive coupler and a burr having a cutting edge with at least one radial projection joining a leading and a trailing edge and rotating said fluid through the outer sheath as the cutting edge is rotated.

Abstract: Apparatus for removing a lead from a lumen of a subject including a flexible control tube shaped to define a control-tube lumen; and a flexible grasping tube shaped to define a grasping-tube lumen. The grasping tube is disposed within the control-tube lumen and includes a torque-transfer non-distal portion; and a helically-cut distal portion, that is (a) fixed at a distal end thereof to a distal end of the control tube, and (b) rotatable at least at a proximal end thereof with respect to the control tube. The helically-cut distal portion is configured to grasp the lead within the grasping-tube lumen upon the proximal end of the helically-cut distal portion being rotated with respect to the control tube.

Abstract: The disclosed invention includes an apparatus for cutting biological tissue in a substantially uniform manner and method for using the same.

Abstract: A user friendly, safe and efficient continuous flow irrigation endoscope having only a single housing sheath without an inner sheath. The exclusion of the inner sheath increases the effective lumen of the endoscope. A long hollow cylindrical tube, capable of performing a to and fro and rotary motion, is placed inside the housing sheath to function as an endoscopic instrument, but also to serve as a conduit for evacuating waste fluid and detached tissue pieces present inside a tissue cavity. A single inflow port located at the proximal end of the single housing sheath allows the irrigation fluid to enter the tissue cavity via the lumen of the said housing sheath. The invented endoscope system has a single inflow port, a single outflow port, without an inner sheath so that all waste fluid and tissue debris present inside cavity are evacuated via the same single outflow port.

Abstract: A cleaning device for cleaning a catheter lumen of a tissue removal catheter has a flushing chamber with distal and proximal seals and an inlet port. The proximal seal is a duckbill seal that includes a pair of opposing duckbill members that slidingly accept the distal end portion of a catheter body to form a seal about the catheter body proximal to a proximal opening in of the catheter lumen. Fluid is directed in the inlet port, into the flushing chamber, into proximal opening in the catheter body, and through the catheter lumen to discharge tissue contained in the catheter lumen. In some embodiments, the cleaning device is preloaded on the catheter body. The cleaning device can have an internal stop that engages with an external stop on the catheter body when the cleaning device is positioned in an operative position.

Abstract: A surgical cutting device may be made of one or more pieces and include a front edge having a plurality of incision points. The incision points may be the forwardmost points of the front edge and may be separated by a recessed portion. The surgical cutting device may also have lateral edges that are non-cutting surfaces.

Abstract: A method of treating a lesion in a body lumen to enlarge a passageway in the lumen including providing a cutting member, connecting a tracking member to the cutting member to form an assembly, inserting the connected cutting member and tracking member through a first lumen of a catheter, withdrawing the catheter from the cutting member and tracking member, inserting the catheter over the tracking member and leaving the cutting member outside the catheter, and expanding a portion of the catheter to move the cutting member into cutting contact with the lesion. A device for treating a lesion in a body lumen including a cutting member having a coupler to connect a tracking member is also provided.

Abstract: An apparatus and method are provided for accessing and/or removing material from a body lumen. The apparatus includes a tubular sheath including a shaft having a proximal end and an expandable distal end that is expandable between a collapsed configuration and an expanded, tapered configuration. A treatment member can be introduced into the body lumen through the tubular sheath. The treatment member includes one or more expandable members to interact with the material to be removed from the body lumen.

Abstract: In a suction catheter to cut an object, such as a blood clot, formed in a blood vessel and retrieve by suction the object immediately after the cutting, a cutting portion of the object cutting means has a first end connected to a power transmission rod on the leading-end side of the leading-end case portion of the catheter and a second end fixed to an internal wall surface of the leading-end case portion on the base-end side thereof.

Abstract: Disclosed is a medical intervention apparatus. The medical intervention apparatus includes a needle rotation unit configured to include a first needle rotation member, a second needle rotation member that is disposed to be separated from the first needle rotation member, and a first driver that drives the first and second needle rotation members to rectilinearly move in opposite directions and a needle insertion unit configured to insert a needle, which is inserted between the first needle rotation member and the second needle rotation member, into a target.

Abstract: Various methods and devices are provided for accessing an interior surgical site using an access portal which can be inserted and removed with minimal tissue damage and which can form a seal with tissue while inserted. Generally, a device is provided having a rigid elongate surgical access member with a lumen extending therethrough that is configured to receive a surgical tool. The device can also include a flexible sleeve having a lumen extending therethrough that is configured to receive the elongate surgical access member. A substantially rigid collar is provided disposed adjacent to a proximal end of the flexible sleeve and having a lumen extending therethrough that is configured to receive the elongate surgical access member.

Abstract: Described are pelvic implants (e.g., urinary incontinence sling, hammock, etc.) and method of inserting a pelvic implant that provide treatment for pelvic floor disorders such as incontinence or stress urinary incontinence.

Abstract: The present invention is directed to a dermabrasion device (1) comprising a handle portion (3), a head portion (2) having two arms (4, 5) arranged to receive and hold a drum (6) having an abrasive surface wherein the abrasive surface is in the form of a convex curve such that the diameter at the centre of the drum (6) is greater than the diameter of the ends of the drum (6).

Abstract: This disclosure includes surgical anchors and related devices and methods that can be used for surgical bone fracture fixation. Some embodiments involve the use of a polymeric cored braided suture that can be held in place by anchors implanted or inserted into bone on each side of a fracture. In some embodiments, the present anchors can be secured into the bone while maintaining high tension (e.g., relative to certain prior art methods) in the suture during the deployment process. Some embodiments can provide for tensioning (e.g., using a polymeric cored braided suture) to compress the fracture and hold the bone in place, functioning as though the suture has sewn the bone (e.g., fragments or portions) together. This can, for example, provide rigid fixation of a fracture which may be important for healing to occur. The tension preload can provide compression to maintain fixation in the face of tensile and shear loads applied to the bone (e.g., as a result of movement and weight bearing).

Abstract: System, including methods and devices, for bone fixation with a pin and a collar. In exemplary embodiments, the system may comprise a pin configured to be inserted into a bone, and a deformable collar to retain the pin in the bone. The collar may be configured to be operatively disposed on the pin such that the collar extends more than halfway and less than completely around the pin. The pin and the collar may have complementary surface features that discourage sliding of the collar along a long axis of the pin. In some embodiments, the collar may be configured to be operatively disposed on the pin at a plurality of discrete, alternative axial positions along the long axis of the pin. The pin may be cut to a desired length.

Abstract: Technologies are generally provided for devices, systems, and methods to provide spinal fixation, spinal stabilization, and/or spinal fusion. Example devices may include a first end and a second end with a middle portion extending between the first and second end. The first end may be configured to be in contact with a portion of a first or upper vertebra and the second end may be configured to be in contact with a portion of a second or lower vertebra in an adjacent vertebral pair. Portions of the vertebra which may be in contact with the device may include lamina, processes, vertebral bodies, and facet joints. The example devices may include bone engagement features, such as screws or similar fasteners, to enhance stabilization and fixation when in contact with the vertebrae. Additionally, the devices may include a bone integration feature to promote bone growth and to facilitate fusion between the vertebrae.

Abstract: Orthopedic fixation devices and methods of installing the same. The orthopedic fixation device may include a coupling element and a bone fastener, whereby the bone fastener can be loaded into the coupling element through the bottom of a bore in the coupling element.

Abstract: A transverse connector for coupling between first and second elongate members of a spinal stabilization system. The transverse connector includes a connector arm, a first coupling assembly proximate a first end of the arm, and a second coupling assembly proximate a second end of the arm. The first and second coupling assemblies are secured to the connector arm through a plurality of mating engagement features, such as dovetail grooves.

Abstract: The present invention provides systems and methods for stabilizing or adjusting the position of at least one spinal motion segment.

Abstract: Disclosed are fixation devices for repairing spondylolysis. The fixation device can include a first anchor, a second anchor, and a bridge that couples the first and second anchors together. In use, the first anchor can be implanted on one side of a pars fracture, the second anchor can be implanted on the other side of the pars fracture, and the bridge can span across the pars fracture. In some embodiments, the fixation device can be compressible to promote healing of the fracture.

Abstract: The invention concerns an implantation assembly comprising a bone-anchoring element comprising a threaded rod provided at one of its ends with a head and an instrument for driving the bone-anchoring element, said instrument comprising a drive spindle removably premounted on the bone-anchoring element.

Abstract: The improvement is a spinal instrument (preferably, a bone screw driver) having a flexible shaft comprising a plurality of interlocking segments carried on a malleable core rod. The flexible shaft allows a screwdriver handle to be perfectly in-line with the cage inserter if desired, while still taking advantage of the tactile feel and torque transmission of the flex segment in its bent position. Accordingly, a surgeon can limit the amount of retraction and keep the driver handle close to the inserter without having to overcome the forces of the flexible segments' natural straight configuration.

Abstract: The invention relates to a bone plate system with a bone plate, a pressure plate, and a bone screw. The bone plate comprises a through-hole, said through-hole having a seat surface with a variable angle for the bone screw. In the connected state of the system, the bone screw is inserted into the through-hole. The head of the bone screw is enclosed between the bone plate and the pressure plate. The pressure plate is fixed to the bone plate via a screw connection which has two securing screws. The axes of the securing screws spread apart such that the distance between the axes of the securing screws increases in the screw-in direction. The head of the bone screw is thereby reliably fixed between the pressure plate and the bone plate.

Abstract: A bone plate sized and shaped for fixation to a phalangeal bone includes a head extending from a first end to a second end and having first, second and third fixation element holes extending therethrough and arranged in a triangular configuration on the head, an outer wall of the head having a triangular shape corresponding to the triangular configuration, a bone contacting surface of the head being contoured to conform to the anatomy of a lateral surface of a phalangeal head and a shaft extending from the head, the shaft including fourth and fifth plate holes separated from one another by an elongated fixation element hole elongated in a direction parallel to a longitudinal axis of the shaft.

Abstract: A bone plate sized and shaped for fixation to a metacarpal includes a head extending from a first end to a second end and having first and second fixation element holes extending therethrough along first and second fixation element hole axes, wherein the first hole axis diverges from the second hole axis on a bone facing side of the plate, the head having a first notch on the first end centered on the central longitudinal axis, the first notch formed as a indentation on an outer wall of the bone plate sized and shaped to accommodate a collateral ligament when the plate is fixed to a metacarpal in a desired position and a shaft extending from the second end of the head to a third end along the central longitudinal axis, the shaft including an elongated fixation element hole elongated in a direction parallel to the central longitudinal axis.

Abstract: A bone plate for fixation to a phalanx includes a head extending from a first end to a second end and having first and second fixation element holes extending therethrough, a connection portion extending from the second end of the head to a third end along the central longitudinal axis, the connection portion including an oblong hole elongated in a direction parallel to the central longitudinal axis, and a shaft extending from the third end of the connection portion to a fourth end along the central longitudinal axis. The shaft includes third and fourth fixation element holes extending along the central longitudinal axis. The shaft includes a plurality of first projections and a plurality of second projections. The first and second projections include corresponding projection fixation element holes extending therethrough and being connected to the shaft. The first and second projections are alternatingly provided on the shaft.

Abstract: A bone plate sized and shaped for fixation to one of a phalangeal and metacarpal bone includes a head extending from a first end to a second end and having an elongated curved plate hole extending therethrough along a curved path from a first end to a second end, a plate hole axis of the elongated curved plate hole extending orthogonally from a top surface to a bone contacting surface of the bone plate and a shaft extending from the head, the shaft including an elongated shaft plate hole extending therethrough and elongated in a direction extending orthogonal to a central longitudinal axis of the bone plate, a plate hole axis of the elongated shaft plate hole extending orthogonally from the top surface to the bone contacting surface.

Abstract: A bone plate sized and shaped for fixation to a phalangeal bone includes a head extending from a first end to a second end and having first, second third and fourth fixation element holes extending therethrough and arranged in a diamond configuration on the head, an outer wall of the head having a diamond shape corresponding to the diamond configuration, a bone contacting surface of the head being contoured to conform to the anatomy of a dorsal surface of a first metacarpal, the contour being curved to be seated over a protuberance at a head of the first metacarpal and a shaft extending from the head, the shaft including an elongated fixation element hole elongated in a direction parallel to a longitudinal axis of the bone plate.

Abstract: A pair of forceps includes a first arm extending from a proximal end to a distal end and a second arm extending from a proximal end to a distal end, the second arm connected to the first arm at a pivot point in combination with a first leaf spring coupled to an inner surface of the first arm at a first attachment point and curved toward the second arm and a switch coupled to an inner surface of the second arm and having a switch opening extending therethrough receiving the first leaf spring to form a ratchet mechanism maintaining a desired position of as the first and second arms relative to one another as they are radially compressed to a grasping configuration.

Abstract: A screwdriver includes a handle having a handle channel extending therethrough and a shaft extending from a proximal end insertable into the handle channel to a distal end including a bit opening sized to receive a proximal portion of a bit therein in combination with a locking sleeve slidably receiving the shaft therethrough and positionable over the shaft distally of the handle and a spring slidably received within the locking sleeve channel over the shaft. A coupling member received over the shaft distally of the locking sleeve is movable from a biased first configuration in which a locking element protrudes radially into the bit opening to lockingly engage a bit received therein and a second configuration in which the coupling member is retracted proximally to compress the spring and permit the locking element to move radially out of the bit opening to permit the bit to be removed therefrom.

Abstract: A medical device system may be configured to detect an improper energy transmission configuration therein. The condition may be detected by way of a detection of a condition where an energy-transmitting electrode of the medical device system becomes too close to or becomes in contact with an object resulting in an inability of the electrode to properly transmit energy. For example, if the energy-transmitting electrode is a first electrode configured in its operational state to transmit energy to bodily tissue adjacent the first electrode, but the first electrode is inadvertently contacting a second electrode, such contact may cause at least some energy transmitted by the first electrode to follow an unintended path away from its intended path to the adjacent tissue. Such a condition may be detected based at least upon an analysis of information acquired from a sensing device system.

Abstract: A treatment device configured to hold a living tissue includes a swing member supported by a first grasping member and rotatable in a first direction and in an opposite direction opposite to the first direction. A support shaft of the swing member is supported on a side close to the distal end including a middle position between the distal end and the proximal end. A first holding surface is provided on the swing member close to a side of the second grasping member and grasps the living tissue. A second holding surface is provided on the second grasping member close to a side of the swing member and which faces the first holding surface and which is configured to hold the living tissue together with the first holding surface of the swing member.

Abstract: An irrigating bipolar forceps may include a first forceps arm, a conductor tip of the first forceps arm, a second forceps arm, a conductor tip of the second forceps arm, an input conductor isolation mechanism, and irrigation tubing. A proximal end of the first forceps arm may be disposed within the input conductor isolation mechanism and a proximal end of the second forceps arm may be disposed within the input conductor isolation mechanism. An application of a force to a lateral portion of the forceps arms may be configured to close the forceps arms. A reduction of a force applied to a lateral portion of the forceps arms may be configured to open the forceps arms. The irrigation tubing may transport a fluid from an irrigation supply system to a surgical site.

Abstract: A sealing instrument (10) including two branches (15, 16) with sealing jaws (19, 20, 36, 37) acted on by a sealing voltage preferably between 80 and 120 volts. Tissue receptacles (53, 54) are separated from one another by a wall-like extension (24), which at its lower edge carries a cutting electrode (31), are defined between the branches (15, 16). A cutting voltage from 300 to 500 volts is applied between a branch (16) and the cutting electrode. When the branches are closed the grasped tissue is sealed simultaneously between the sealing jaws (19, 36 and 20, 37) and is severed by the cutting electrode (31). Even though the tissue is severed completely; for example after 0.3 to 0.5 seconds and the sealing requires more time, the rolls of tissue grasped in the tissue receptacles (53, 54) act as form-fitting protection of the vessel edges in the tool (12).

Abstract: A method and apparatus are disclosed for providing forward fluid delivery through an energy delivery device that avoids coring when it delivers energy to a tissue. The device has a distal face defining an opening, with the distal face including at least one electrically exposed portion and at least one electrically insulated portion. An embodiment of the energy delivery device includes an elongate member defining a lumen structured to receive a fluid, and a distal face defining an aperture in communication with the lumen. The distal face includes an electrically exposed conductive portion and an electrically insulated portion. The electrically exposed conductive portion is configured such that the energy it delivers while the energy delivery device is advanced into a tissue punctures the tissue without the tissue substantially occluding the lumen and without creating embolic particles.

Abstract: A method and apparatus for treating tissue are disclosed, including intra-operative mapping of a probe ablation zone. The method uses a system that maps the proximal and distal margins of the probe ablation zone using tools that access the ablation target. In some embodiments, the tools comprise a bone drill, and an introducer assembly, including a cannula and a stylet. The tools have features or markings that cooperate to indicate which probe to use to achieve the desired ablation. The method further facilitates planning probe placement for delivering energy to treat (ablate) a desired ablation volume of a target tissue by using a system that maps both the target tissue and possible probe ablation zones.

Abstract: A catheter includes a braid assembly having a dual-laminate coating. The braid assembly includes a plurality of braid members interwoven to provide for interstices between the braid members, each braid member having an electrically conductive element, a flexible non-electrically-conductive polymer coating that insulates the electrically conductive element and a thermoplastic bonding adhesive coating. The braid assembly is formed between an inner polymer layer and an outer polymer layer. One or more of the braid members may be coupled to an energy delivery element.

Abstract: A surface of an object comprises a material having a low surface energy. A first cover comprising a material having a higher surface energy than the surface of the object may cover and be affixed to the surface. A second cover may be adhered to and/or secured by the first cover so that the second cover is fixedly coupled to the surface of the object.

Abstract: A radio frequency ablation device, comprising a radio frequency ablation tube (10), a control handle (20) and a temperature-controlling radio frequency instrument (35). The middle section of the radio frequency ablation tube (10) carries a strip-shaped connecting electrode; a radio frequency electrode (12) is formed at the distal end of the radio frequency ablation tube (10) and connected to the control handle (20) via the strip-shaped connecting electrode. The control handle (20) comprises a control guiding control a tube electrode control handle (23) and a tube electrode auxiliary control handle (24) An integrated interface (50) is disposed at the rear of the control handle (20), and the temperature-controlling radio frequency instrument (35) is connected to the integrated interface (50) via an integrated cable (34). And a radio frequency electrode (12) a radio frequency ablation tube (10) and a guide tube (16) are also provided.

Abstract: Devices, systems, and methods for performing ablation therapy on body tissue are disclosed. An example ablation device for treating body tissue includes an ionically conductive balloon and a radio-frequency electrode that delivers RF energy into a distal section of the balloon. The balloon is configured to transmit the RF energy in a direction distally towards a leading end of the ablation device. Multiple ablation electrodes on the device can be used for providing lesions of different size or shape.

Abstract: Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. One or more measurable physiological parameter corresponding to the polycystic kidney disease can thereby be reduced. Moreover, central sympathetic drive in the patient can be reduced in a manner that treats the patient for the polycystic kidney disease. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.

Abstract: The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy.

Abstract: An adjustable stringer configured to string the ring handles of one or more surgical instruments, the stringer including two or more rod sections, wherein each rod section is configured to be inserted in one ring handle of the one or more surgical instruments, two or more angle sections, each angle section configured having one or more slidable connector sections, each slidable connector section configured to extend and retract along at least one of the two or more rod sections, and two or more releasable connectors, each releasable connector positioned between two of the two or more angle sections.

Abstract: A shipping container integrates a sharps disposal container with a new product storage container for shipping. The storage container stores new product. A sharps disposal container receives used sharps. One of the storage container and the sharps disposal container is disposed within the other of the storage container and the sharps disposal container for shipping. A lid is adapted to be connected to the outermost container of the sharps disposal container and the storage container for shipping and to a top of the sharps disposal container for receiving used sharps.

Abstract: A glove dispenser has a housing having first and second opposed walls. A glove roll is disposed within the housing for carrying a roll of removable gloves. An electro-mechanical feed mechanism rotates the roll. One or more proximity sensors are positioned within the housing to detect a user's hand and activate rotation of the glove roll. Activators are located on the housing first and second wall which activate the roll to rotate to dispense a glove from the roll. A take-up roll can be provided for receiving roll material after the gloves are dispensed.

Abstract: The present disclosure relates to a surgical drape to be used in conjunction with a surgical procedure, and more specifically to a surgical drape that includes one or more of the following: (1) a patient drape for use with a standalone non-draped image acquisition device; (2) a patient drape for use with a standalone non-draped image acquisition device with image guidance navigation technology; (3) the means to provide temporary sterile coverage of an underlying sterile field; (4) the means to provide sterile separation of at least a portion, if not the entire temporary sterile coverage; and (5) the means to provide covering of the undersurface of the operating surface and enclosing any suspended medical devices, wires, cables, tubes, etc.

Abstract: A cranial alignment device for use in intracranial stereotactic radiotherapy includes a nosepiece that is custom shaped to mate with the dorsum and alae of the patient's nose.

Abstract: A device for manipulating a magnetic coupling force across tissue in response to a monitored coupling force is described. The device includes a magnetic field source assembly, a positioning assembly operatively connected to the magnetic field force assembly, and a magnetic coupling force monitor. The magnetic field source assembly includes magnets that provide an external magnetic field source for providing a magnetic field across tissue. The positioning assembly adjusts the position of the magnetic field source. The magnetic field creates a magnetic coupling force between the external magnetic field source and an object positioned in use in a patient during a procedure, wherein the object has or is associated with an internal magnetic field.