Abstract: Borescopes for medical and other uses. In some embodiments, a portable borescope may comprise a dongle comprising an image processor may be coupleable with the borescope and may be configured to receive image data from an image sensor within a tip assembly of the borescope. In some embodiments, the image processor may be within a mobile general purpose computing device coupled to the borescope. One or more components of the borescope and/or tip assembly may be disposable. In some embodiments, the borescope may be configured to limit at least one of a duration and a number of uses of the borescope, or at least a portion of the borescope, to a preconfigured value.

Abstract: Methods and systems for navigating to a target through a patient's bronchial tree are disclosed including a bronchoscope, a probe insertable into a working channel of the bronchoscope and including a location sensor, and a workstation in operative communication with the probe and the bronchoscope, the workstation including a user interface that guides a user through a navigation plan and is configured to present a central navigation view including a plurality of views configured for assisting the user in navigating the bronchoscope through central airways of the patient's bronchial tree toward the target, a peripheral navigation view including a plurality of views configured for assisting the user in navigating the probe through peripheral airways of the patient's bronchial tree to the target, and a target alignment view including a plurality of views configured for assisting the user in aligning a distal tip of the probe with the target.

Abstract: Methods and systems for navigating to a target through a patient's bronchial tree are disclosed including a bronchoscope, a probe insertable into a working channel of the bronchoscope including a location sensor, and a workstation in operative communication with the probe and the bronchoscope the workstation including a user interface that guides a user through a navigation plan and is configured to present a three-dimensional (3D) view for displaying a 3D rendering of the patient's airways and a corresponding navigation plan, a local view for assisting the user in navigating the probe through peripheral airways of the patient's bronchial tree to the target, and a target alignment view for assisting the user in aligning a distal tip of the probe with the target.

Abstract: A steerable device, such as a steerable catheter, may include a control handle and an insertion shaft extending outwardly therefrom. In use, the insertion shaft is navigated to an area of interest for examination and/or treatment thereof. The steerable device may include a steering system that controls the deflection angle of the distal end of the insertion shaft in two or more non-planar directions for navigating the insertion shaft to the area of interest. The steering system may also include a locking mechanism for arresting or partially arresting the movement of the distal end of the insertion shaft in a first direction independent of arresting or partially arresting the movement of the distal end in a second non-planar direction.

Abstract: Single use laryngoscope handle for use in an ISO 7376 compatible dual component laryngoscope assembly with an illumination arrangement. The laryngoscope handle includes a plastic hand grip, a plastic end cap, and at least one plastic frangible member for engaging a hand grip and an end cap in a pre-actuated position of an end cap which is broken on application of a relatively minor manual detachment force to the end cap, thereby precluding subsequent use of the laryngoscope handle.

Abstract: An endoscope system includes: an image pickup apparatus in which an insertion portion is detachable, the image pickup apparatus picking up an optical image of light from an observed object; a focus changing section that can change focus of the image pickup apparatus; a control section that generates a control signal to control the optical image in a focused state in a state in which the insertion portion is fitted to the image pickup apparatus; a storage section that stores data associating a type of the insertion portion and control information; an identification section that reads a predetermined code to identify the type of the insertion portion; and an optical characteristic acquiring section that acquires the control information corresponding to the type of the insertion portion identified by the identification section to acquire an optical characteristic of the insertion portion used to generate the control signal.

Abstract: An endoscope system includes an image pickup device that is inserted into a subject and picks up an image inside the subject and a memory that records an intra-subject image acquired by the image pickup device and position information of the image pickup device in association with each other. The endoscope system includes an image generating section that applies, to the intra-subject image, when it is determined that a release signal is generated as a predetermined trigger signal, predetermined processing for distinguishably displaying the intra-subject image at a time when the release signal is generated and generates an image obtained by pasting the intra-subject image onto a model image of a predetermined organ.

Abstract: A housing containing an electrical energy source is coupled between a first end cap comprising a control and an interstitial member comprising an LED selectively electrically couplable to the electrical energy source by the control, and a second end cap coupled to the interstitial member comprises an optical filtering component in optical alignment with light emitted by the LED. At least a portion of an exterior of at least one of the housing, the first end cap, the interstitial member, and the second end cap may have a cross-sectional shape that is not substantially circular. The end caps, housing, interstitial member, and optical filtering component may each be sealingly interconnected. A method of using the apparatus may comprise directing light emitted by the apparatus into a human oral cavity without inserting the apparatus into the human oral cavity.

Abstract: A LED illumination module has at least one LED (6). At a proximal side there is a first electric connection contact (8) and at an axially oppositely directed distal side there is a second electrical connection contact (10) as well as a radiation region emitting radiation. The LED (6), at the second electrical connection contact (10), is contacted via an electrically conductive sleeve (14) which, distanced to the proximal end, is electrically conductively connected to the second connection contact (10) of the LED (6).

Abstract: A chemical bottle is inclined by a bottle push-up mechanism, and a chemical solution is gravitationally injected into a chemical tank from a chemical supply tube line. When a chemical tray is drawn out after completion of chemical injection, the bottle push-up mechanism returns to a planar initial state. In connection with this, the chemical bottle returns to an original set position in which the chemical bottle is in a horizontal state or a plug section faces upward with respect to a gravity direction. This prevents the chemical solution remaining in the chemical bottle from flowing to an outside by gravity.

Abstract: An airway-blocking device is disclosed. The airway-blocking device includes a conduit having a branched proximal end, a branched distal end, and first and second lumens extending from the branched proximal end to the branched distal end. The branched proximal end includes a first air supply connection and a second air supply connection. The branched distal end includes a first sealing balloon and a second sealing balloon. The first air supply connection is in fluid communication with the first sealing balloon through the first lumen of the conduit, and the second air supply connection is in fluid communication with the second sealing balloon through the second lumen of the conduit. The first air supply connection is visually distinguishable from the second air supply connection. An assembly is also disclosed that includes a bronchoscopic manifold and the airway-blocking device. A method for performing a treatment on airways of a patient using the assembly is also disclosed.

Abstract: A scanning flexible endoscope includes a tether attached to a capsule. The tether controls a disposition of the capsule within a body lumen such as the esophagus. A scanning device in the capsule optically scans the adjacent tissue on the inside surface of the body lumen as the capsule is moved axially through the body lumen. A non-contact sensor responds to indicia on the tether to measure a relative position of the tether and the capsule in the body lumen. The indicia can be analog or digital in form and the sensor can be either magnetic, or optical. A wiper is optionally provided to remove bodily fluids from the tether when pulled from the body lumen past the sensor. A pulse of fluid can be delivered to the distal end of the tether to cause the body lumen to distend, facilitating free movement of the capsule in the lumen.

Abstract: An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening.

Abstract: A method of evaluating the efficiency of a myopia control product for a wearer, the method comprising: an initial myopia indicator providing step S1, during which the initial value of a myopia indicator of the wearer is provided, a myopia condition step S2, during which the wearer using the myopia control product is placed in myopia inducing conditions, a resulting myopia indicator determining step S3, during which the resulting value of the myopia indicator of the wearer is determined after the wearer has been placed in the myopia inducing conditions, an efficiency evaluation step S4, during which the efficiency of the myopia control product is evaluated by comparing the initial value of the myopia indicator and the resulting value of the myopia indicator.

Abstract: The present invention relates to structural analysis of the optic nerve head (ONH). In one approach, a 3D volume of intensity data which includes the optic nerve head is acquired using an optical coherence tomography (OCT) system. The vitreoretinal interface (VRI) and the optic disc margin are identified from the 3D data. The minimum area of a surface from the optic disc margin to the VRI is determined. This minimum area can be displayed as an image or in the alternative, a value corresponding to this minimum area can be displayed. The minimum area measurement provides relevant clinical information to determine the health of the eye.

Abstract: A system and method for measuring a characteristic of an eye of a subject receive data pertaining to the subject; assign the subject to an assigned age category based on the data pertaining to the subject; adjust a brightness level of a fixation target according to the assigned age category for the subject; provide the fixation target for a subject to view; and objectively measure at least one characteristic of the eye of the subject while the subject views the fixation target at the adjusted brightness level.

Abstract: There is disclosed herein a system for measuring visual fixation disparity comprising a display apparatus for presenting stereoscopic visual content to a patient. A sensing apparatus tracks eye movement of the patient. A controller controls the display apparatus to stereoscopically display a central image target alternately to a left eye and a right eye of the patient and tracking eye movement for a period of time as the central image target is alternated between the left eye and the right eye, and incrementally relocating the central image target left and right images until the patient perceives the left and right images to be physically coincident.

Abstract: An optical measurement system and method measure a characteristic of a subject's eye. The optical measurement system receives from an operator, via a user interface of the optical measurement instrument, a begin measurement instruction indicating the start of a measurement period for objectively measuring at least one characteristic of the subject's eye. Subsequent to receiving the begin measurement instruction, the optical measurement system determines whether a criterion associated with the tear film quality of the subject's eye is not satisfied. In response to determining that the criterion is not satisfied, the optical measurement instrument takes one or more corrective actions to measure the characteristic of the subject's eye under a condition wherein the criterion is satisfied.

Abstract: Systems and methods for sub-aperture correlation based wavefront measurement in a thick sample and correction as a post processing technique for interferometric imaging to achieve near diffraction limited resolution are described. Theory, simulation and experimental results are presented for the case of full field interference microscopy. The inventive technique can be applied to any coherent interferometric imaging technique and does not require knowledge of any system parameters. In one embodiment of the present application, a fast and simple way to correct for defocus aberration is described. A variety of applications for the method are presented.

Abstract: Systems and methods are presented for acquisition and processing of spectrally dispersed illumination optical coherence tomographic data. Light from a source is distributed spectrally on the sample, and each acquisition simultaneously provides partial spectral interference information from multiple locations in the sample. Thus for a given spatial point, a single observation will be of a partial spectrum A-scan. When multiple partial spectrum A-scan observations are made at the same point by shifting the spectrum of light on to the tissue, the point can be observed by the entire broadband spectrum of the light source, thereby making it possible to create a full axial resolution A-scan.

Abstract: An image processing apparatus includes a calculation unit configured to calculate information indicating similarity among a plurality of tomographic images, and a generation unit configured to generate a tomographic image from the plurality of tomographic images based on the calculated information indicating similarity.

Abstract: A corneal topographer includes: a flat panel display configured to display a light pattern and to project the light pattern onto a cornea of an eye disposed on a first side of the flat panel display; an optical system disposed on a second side of the flat panel display, the optical system being configured to receive and process reflected light from the cornea that passes through the flat panel display from the cornea to the optical system; a camera configured to receive the processed reflected light from the optical system and to capture therefrom a reflected light pattern from the cornea produced in response to the projected light pattern; and one or more processors configured to execute an algorithm to compare the projected light pattern to the reflected light pattern from the cornea, and to produce a topographic map of the cornea based on a result of the comparison.

Abstract: The presented invention discloses, in the first aspect, a mobile-device embedded system and apparatus for personalized real-time instant diagnostics of a patient, such a diagnostics produced without human involvement, by scanning a patient's iris with a mini iridology camera, such a camera embedded into the patient' mobile device, and by performing automated real-time iridology analysis by cross-referencing the iridology scan results with diseases data, while iridology analysis package will be pre-installed into the patient' device, and by producing diagnosis if the iridology scan produces results consistent with iris signs indicating the disease. Patient' treatment is recommended by automatically cross-checking a list of diagnosed diseases with the list of treatments. Emergency medical response may be provided automatically to the patient location as determined by GPS/wireless means.

Abstract: Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging of the back and/or front of the eye using multiple illumination modalities, which permits the collection of one or more of reflectance, spectroscopic, fluorescence, and laser speckle contrast images.

Abstract: Methods and devices for implanting an intra-ocular pressure sensor within an eye of a patient are provided herein. Methods include penetrating a conjunctiva and sclera with a distal tip of a fluid-filled syringe and positioning the pressure sensor within a vitreous body of the eye by injecting the sensor device through the distal tip. The sensor device may be stabilized by one or more anchoring members engaged with the sclera so that the pressure sensor of the sensor device remains within the vitreous body. Methods further include advancing a sensor device having a distal penetrating tip through at least a portion of the sclera to position the sensor within the vitreous body and extracting of the sensor devices described herein by proximally retracting the sensor device using an extraction feature of the sensor device.

Abstract: A method of obtaining an image of bone using magnetic resonance imaging, the method comprising the step of selecting the scanning parameters for the magnetic resonance imaging device, wherein the scanning parameters comprise a low flip angle, a short time to repetition and a short time to echo.

Abstract: A microprocessor is operably coupled to a camera from which patient vital signs are determined. A temporal-variation-amplifier of at least two images is operable to generate a temporal variation, a vital-sign generator is operable to generate at least one vital sign from the temporal variation and a display device is operable to display the at least one vital sign.

Abstract: A microprocessor is operably coupled to a camera from which patient vital signs are determined from reduced images. A temporal-variation-amplifier of at least two reduced images is operable to generate a temporal variation, a vital-sign generator is operable to generate at least one vital sign from the temporal variation and a display device is operable to display the at least one vital sign.

Abstract: Apparatus and methods are presented herein that permit real-time, accurate detection of residual tumor in the operating room. The Raman-based wide-field imaging apparatus and methods described herein permit real-time imaging of tumor-targeted R-MR nanoparticles over a wide field.

Abstract: A diagnostic instrument comprises a monochromatic light source, transmission means to transmit light from the light source to a test site, collection means to transmit scattered light from the test site, and spectral analysis apparatus to receive light from the collection means, the spectral analysis apparatus comprising a diffraction grating having a first grating element and a second grating element, wherein the first grating element diffracts light within a first wavelength range and the second grating element diffracts light within a second wavelength range, the spectral analysis apparatus further comprising a light-sensing apparatus, the first grating element arranged to diffract light onto a first area of the light-sensing apparatus and the second grating element arranged to diffract light onto a second area of the light-sensing apparatus.

Abstract: A microprocessor is operably coupled to a camera from which patient vital signs are determined. A temporal variation of images from the camera is generated and amplified from which the patient vital sign, such as heart rate or respiratory rate, can be determined and displayed or stored.

Abstract: An apparatus for dental confocal imaging comprises an illumination module for generating an array of light beams, an optics system for confocal focusing of the array of light beams and a probe head with a light-guiding part having an entrance face and an exit face. The illumination module, the optics system and the probe head are arranged such that the array of light beams from the illumination module passes through the optics system, enters the light-guiding part via the entrance face and exits the light-guiding part via the exit face. The optics system is configured such that, after having passed through the optics system, the outermost marginal rays of the outermost light beams with respect to the optical axis of the optics system are parallel or divergent to the optical axis.

Abstract: A photoacoustic image production device includes a light source that emits light, a light source driver that causes the light source to emit the light, an ultrasonic wave detector that receives an ultrasonic wave and produces an ultrasonic wave detection signal, an image signal production component that produces an ultrasound image based on the ultrasonic wave detection signal, and a controller that controls the light source driver to stop operation of a booster circuit during a first reception period in which the ultrasonic wave detector receives the ultrasonic wave produced by the light emitted from, the light source.

Abstract: A microprocessor is programmed to execute a spatial bandpass filter that is operable to apply spatial bandpass filtering to a plurality of images, a regional facial clusterial module that is operably coupled to the spatial bandpass filter and that applies spatial clustering to output of the spatial bandpass filter, a temporal bandpass filter that is operably coupled to the regional facial clusterial module and that is applied to output of the regional facial clusterial module, a temporal-variation identifier that is operably coupled to the temporal bandpass filter and that identifies a temporal variation of the output of the temporal bandpass filter and a vital-sign generator that is operably coupled to the temporal-variation identifier that generates a biological vital sign from the temporal variation.

Abstract: A non-touch thermometer senses temperature from a digital infrared sensor is described. A microprocessor is operably coupled to a camera from which patient vital signs are determined. A digital signal representing a temperature without conversion from analog is transmitted from the digital infrared sensor. A temporal variation of images is generated from which a heart rate and the respiratory rate can be determined and displayed or stored.

Abstract: A method, apparatus, and computer program monitor a user's heart activity during a physical exercise. A heart activity measurement signal representing the user's heart activity is acquired and a phase component of the heart activity measurement signal is monitored. On the basis of the monitoring of the phase component, one or more actions are carried out.

Abstract: A microprocessor is operably coupled to a digital infrared sensor from which temperature is determined from the digital infrared sensor.

Abstract: An apparatus comprises plurality of sensors and a processor. Each sensor provides a sensor signal that includes physiological information and at least one sensor is implantable. The processor includes a physiological change event detection module that detects a physiological change event from a sensor signal and produces an indication of occurrence of one or more detected physiological change events, and a heart failure (HF) detection module. The HF detection module determines, using a first rule, whether the detected physiological change event is indicative of a change in HF status of a subject, determines whether to override the first rule HF determination using a second rules, and declares whether the change in HF status occurred according to the first and second rules.

Abstract: A biometric information detecting apparatus is provided. The biometric information detecting apparatus includes a fixing unit disposed on a lower structure, and a pressure pulse wave measuring unit that is supported by the fixing unit and separate from the lower structure. An optical pulse wave measuring unit is disposed on the pressure pulse wave measuring unit. The optical pulse wave measuring unit may contact a surface of a subject's body. A pressure pulse wave of the subject's body may be measured by the pressure pulse wave measuring unit and an optical pulse wave of the subject's body may be measured by the optical pulse wave measuring unit, at the same time.

Abstract: A device used to quickly measure central venous pressure is disclosed. Compared to current systems, the JVPM is easier to use, less expensive, and faster in providing the needed information to determine both the course of treatment and the proper positioning of the inserted catheter. As a physically smaller device that remains within the sterile operative field, the JVPM is also less likely to introduce infecting organisms into the body.

Abstract: In some embodiments, a method and/or device are disclosed for measuring a pressure drop over a portion of a body lumen. Optionally, the pressure drop for two different flow conditions may be used to find the stiffness of the lumen. In some embodiments the device may be calibrated, for example by correcting for distortion, for example the common mode pressure distortion. Pressure drop and or stiffness measures may be used to evaluate a treatment procedure and/or a stenosis.

Abstract: A blood pressure measurement cuff wrapped a direction along circumferential direction around a measurement site, the blood pressure measurement cuff containing fluid bladder between belt-shaped body composed of inner cloth to be in contact with the measurement site and outer cloth opposing the inner cloth. Ring attachment member attached to a region on inner circumferential end-side of the outer cloth and hook-and-loop fastener provided in a region on outer circumferential end-side of the inner cloth are included. The ring has a temporary fastening structure that allows a region continuous with outer circumferential end of the belt-shaped body to be pulled through ring with arm strength in a direction away from measurement site during attachment and suppresses a case in which the region continuous with the outer circumferential end of the belt-shaped body pulled by the arm strength is pulled back through the ring by elastic force of the measurement site.

Abstract: A method for preventing dozing off, comprising the steps of: a measurement step measuring human heartbeats; a decision step (S4 to S8) generating a trigger, hereinafter referred to as a “drowsiness trigger”, for indicating occurrence of drowsiness when a state in which a time interval between adjacent heartbeats, hereinafter referred to as a “heartbeat interval”, is longer than the previous heartbeat interval consecutively occurs; and a warning step (S9) giving a warning to prevent dozing off when the drowsiness trigger is generated.

Abstract: The present invention describes vertically stacked and hermetically sealed implantable pressure sensor devices for measuring a physiological signal. The implantable device comprises multiple layers, including a first wafer having a pressure sensor configured to measure the physiological signal and a second wafer having at least a digitizing integrated circuit. The first wafer is vertically stacked or disposed over the second wafer so as to form a hermetic seal. The device may include one or more additional layers adapted for energy storage and transfer, such as a third layer having a super-capacitor and a fourth layer having a thin film battery.

Abstract: A monitoring device includes an expansion body that is delivered into a vessel, and that expands at a predetermined position, and an electrode that is attached to the expansion body, and that detects neural activities of a nerve located outside the vessel by coming into contact with an inner wall of the vessel when the expansion body expands.

Abstract: This invention discloses a system and method for extracting VF signal in ECG recorded during uninterrupted CPR. The method and system applies an adaptive algorithm incorporating the EMD and least mean square (LMS) filtering to effectively model the CPR artifacts such as chest compression signals. Thus, A VF signal in ECG recorded during uninterrupted CPR can be extracted without deteriorating the reliability of the waveform parameter (i.e. AMSA) of shockability. The present invention enables uninterrupted CPR performed during recording ECG for accessing the shockability, so that an increase the probability of successful resuscitation is achieved.

Abstract: A conductive lead that connects a medical sensor or probe to a monitoring or analytical machine. The conductive lead is flexible, lightweight and can be manufactured at a very low cost. The conductive lead has a dielectric flexible substrate. Conductive ink is printed upon the flexible substrate. The conductive ink forms contact pads and connection lines on the flexible substrate. The connection lines electrically interconnect the various conductive pads. An insulation layer covers the connection lines The insulation layer can be dialectic ink that is printed atop the conductive ink. Peel-away protective covers are used to cover the contact pads. Any one of the contact pads can be exposed for use by removing the protective cover that covers it. The contact pads are used to electrically interconnect with both the sensor and the machine.

Abstract: The present invention includes (i) a right instantaneous phase determining section (12R) for successively determining an instantaneous phase ?R(f, t) of a right electroencephalography signal XR, (ii) a left instantaneous phase determining section (12L) for determining an instantaneous phase ?L(f, t) of a left electroencephalography signal XL, (iii) a phase synchronization index calculating section (13) for successively calculating a phase synchronization index PSI(f, t), and (iv) a video signal generating section (14) for generating a video signal representing a video image whose content changes in correspondence with the phase synchronization index PSI(f, t).

Abstract: A cardiac monitoring device includes: at least one sensing electrode for obtaining an electrocardiogram (ECG) signal from a patient; a processing unit comprising at least one processor operatively coupled to the at least one sensing electrode; and at least one non-transitory computer-readable medium comprising program instructions that, when executed by the at least one processor, causes the cardiac monitoring device to: obtain the ECG signal from the at least one sensing electrode; determine a transformed ECG signal based on the ECG signal; extract at least one value representing at least one feature of the transformed ECG signal; provide the at least one value to determine a score associated with the ECG signal, thereby providing an ECG-derived score; compare the ECG-derived score to a predetermined threshold score determined by machine learning; and provide an indication of a cardiac event if the ECG-derived score is one of above or below the predetermined threshold score determined by the machine learning

Abstract: A method and medical device for detecting a cardiac event that includes sensing cardiac signals from a plurality of electrodes, sensing a plurality of beats in response to the sensed cardiac signals, identifying each beat of the plurality of beats as one of a normal beat and a not normal beat, determining at least one of whether a number of beats identified as a normal beat is greater than a normal beat threshold, whether an RR interval associated with the beats identified as being a normal beat is less than a threshold interval, and whether RR intervals associated with the beats identified as being normal beats are within an RR interval range, and identifying the cardiac event as being one of shockable and not shockable in response to the determining.