Patents Issued in February 16, 2016
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Patent number: 9259347Abstract: New bodily cooling techniques are provided. In some aspects of the present invention, a new rapidly-evaporating cooling gel or fluid is sprayed or doused over or about an athlete's body and/or worn garments in thermal-reduction-optimized gravitational, diffusion and movement-induced patterns, to maximize cooling during exercise. In some aspects, a worn garment may serve as the matrix or platform for this distribution of the fluid. In other aspects, tuned, heat-absorbing port-controlling devices cause the release of the cooling gel or fluid from distribution tubes or other channels (e.g., integral to the flexible fabric itself) upon local underlying body heat exceeding a threshold, and resealing (halting release) upon body or regional heat dropping below a threshold. In still other aspects, heat-expanding sub-elements rise away from a body heat source toward a wider region for heat release, while other cooled sub-elements descend and exchange places with them, to absorb more body heat.Type: GrantFiled: January 20, 2013Date of Patent: February 16, 2016Inventor: Christopher V. Beckman
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Patent number: 9259348Abstract: A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.Type: GrantFiled: September 28, 2011Date of Patent: February 16, 2016Assignee: Zoll Circulation, Inc.Inventors: Richard A. Helkowski, Jeremy T. Dabrowiak, Alex L. Lim, Venkata Vishnu Gurukula
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Patent number: 9259349Abstract: A kit of parts comprises a system and instructions for use for controlling patient temperature which uses a central venous line catheter having a heat exchange element. The central venous line catheter is provided with one or more lumens for providing access to the central blood supply of the patient, and with additional lumens for communicating heat exchange fluid to the heat exchange element. Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set transports the heat exchange fluid between the central venous line and the temperature control unit, with a pump serving to circulate the fluid in a closed fluid circuit in the system.Type: GrantFiled: January 23, 2014Date of Patent: February 16, 2016Assignee: Zoll Circulation, Inc.Inventors: Blair D. Walker, Scott M. Evans, David P. Balding, Peter Barker
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Patent number: 9259350Abstract: Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.Type: GrantFiled: September 9, 2015Date of Patent: February 16, 2016Assignee: CooperVision International Holding Company, LPInventors: Victoria Rogers, Andrew Luk, Arthur Back, Samuel Zalipsky
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Patent number: 9259351Abstract: Punctal plugs for delivering therapeutic agents have a body, a portion into which the therapeutic agent is held, a winding about the body, and an enlarged portion or anchor at an end.Type: GrantFiled: November 21, 2012Date of Patent: February 16, 2016Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Victor Lust, Phillip King Parnell, Sr., Vincent G. McAteer, Brian Schwam, Hassan Chaouk
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Patent number: 9259352Abstract: Punctal plugs for delivering therapeutic agents have a body, a portion into which the therapeutic agent is held, a winding about the body, and an enlarged portion or anchor at an end.Type: GrantFiled: November 21, 2012Date of Patent: February 16, 2016Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Victor Lust, Phillip King Parnell, Sr., Vincent G. McAteer, Brian Schwam, Hassan Chaouk
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Patent number: 9259353Abstract: A fluid flow-regulating system includes an electrolysis chamber configured to contain a liquid, and includes first and second electrodes disposed within the electrolysis chamber. A gap between opposing surfaces is sized to promote capillary action of a liquid in the electrolysis chamber that draws the liquid to at least one of the first and second electrodes in a manner allowing the flow-regulating system to be placed in multiple orientations and still have said one of the first and second electrodes wetted by capillary action.Type: GrantFiled: October 11, 2012Date of Patent: February 16, 2016Assignee: Alcon Research, Ltd.Inventors: Cesario P. Dos Santos, Nicholas M. Gunn, Leslie A. Field
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Patent number: 9259354Abstract: A photodisruptive laser delivery system and method for use in eye surgery. The photo disruptive laser delivered in pulses in the range of <10000 femtoseconds, used to create incisions in eye tissue is delivered by novel means to minimize optical aberrations without the use of a complex system of multiply precisely arranged lenses. This novel means include a scanning design that allows the focusing lens to always remain under normal incidence to the photodisruptive laser beam, negating the need for overly complex aberration correction set up. The focusing lens is configured to move within a surrounding beam to facilitate two dimensional controls over the treatment space. Controlling beam divergence prior to focusing allows for 3D incisions. The system and methods of use accomplish precise treatment without the need to contact the patient and can be integrated into standard surgical microscopes to improve operational efficiency and hospital workflow.Type: GrantFiled: June 8, 2012Date of Patent: February 16, 2016Assignee: KeLoTec, Inc.Inventors: Christopher Horvath, Vanessa Isabella Vera
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Patent number: 9259355Abstract: An ear warmer comprises a frame and a fabric member. The frame has an ear portion and a band portion. The ear portion of the frame includes a first side and a second side opposite the first side. The first side of the ear portion defines an interior portion of an opening. The second side of the ear portion defines an exterior portion of the opening. The fabric member includes at least its own ear portion coupled to the ear portion of the frame. The ear portion of the fabric member covers the interior portion of the opening in substantially its entirety and covers less than an entirety of the exterior portion of the opening.Type: GrantFiled: July 3, 2008Date of Patent: February 16, 2016Assignee: 180s, Inc.Inventors: Brian E. Le Gette, David L. Reeb, Alan S. Tipp, Justin Saul Werner
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Patent number: 9259356Abstract: A reduced-pressure abdominal treatment device is presented that has a plurality of liquid-impermeable layers with a foam spacer between two of the liquid-impermeable layers. The plurality of liquid-impermeable layers have a coextensive area A1. The foam spacer has a plan-view area A2. A2 is less than 80% of A1 (i.e., A2<0.8A1). The foam spacer is configured such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta (?) that is typically 360 degrees for a majority of locations in the target fluid removal zone. Applying 360 degrees of reduced pressure helps avoid blockage. The plurality of liquid-impermeable layers may be bonded for various effects. Other devices, systems, and methods are disclosed.Type: GrantFiled: May 28, 2013Date of Patent: February 16, 2016Assignee: KCI Licensing, Inc.Inventors: Tyler Simmons, Alexander G. Sammons
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Patent number: 9259357Abstract: A thin chitosan-based material can be used for biomedical applications. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan material. A single or multiple such treatments may be employed. For example, the chitosan material may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both. A thin chitosan material can be readily treated by surface modifying treatments such as irradiating under nitrogen using ?-irradiation, treating under a nitrogen plasma, or both.Type: GrantFiled: April 16, 2014Date of Patent: February 16, 2016Assignees: Loma Linda University, Loma Linda University Medical Center, North Carolina State UniversityInventors: Wolff M. Kirsch, Samuel M. Hudson, Andrew Crofton
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Patent number: 9259358Abstract: Reduced pressure wound therapy is performed on a sacral region of a patient using an adhesive dressing comprising a flexible planar layer and a non-planar fold-sealing region configured to seal to the intergluteal cleft of a patient. The fold-sealing region is located on an outer edge of the adhesive dressing and comprises a tapered configuration.Type: GrantFiled: January 28, 2013Date of Patent: February 16, 2016Assignee: KCI Licensing, Inc.Inventors: Dean Hu, Kenton Fong, Moshe Pinto, Kenneth Wu, Evan Anderson, Tony Coxum, Brendan Donohoe, Philip Hui, Craig McGreevy
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Patent number: 9259359Abstract: A device including: a main folding mechanism for folding a diaper body in two at the crotch portion by rotating first and second main pads having first and second holding surfaces, respectively; and a sub-folding mechanism for folding the flap by rotating a side pad having a sub-holding surface for holding the flap with respect to the first main pad, wherein; a cut-out is formed at a position corresponding to the attachment portion of the second main pad, wherein the cut-out does not allow the attachment portion to be held by the second main pad but instead expose the attachment portion; with the first and second holding surfaces being closed while opposing each other and with the main body folded in two, the cut-out allows the flap to be attached to the attachment portion; and the side pad rotates from a position where it is open while lying next to the first main pad in the girth direction to a position where the sub-holding surface is closed while opposing the first holding surface, fitting into the cut-ouType: GrantFiled: May 30, 2011Date of Patent: February 16, 2016Assignee: ZUIKO CORPORATIONInventor: Yukihiko Fujita
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Patent number: 9259360Abstract: There is provided a tampon pledget that includes one or more enhanced features that result in the pledget exhibiting increased bypass leakage prevention. These enhanced features may include, but are not limited to, geometry, absorption, and any combinations thereof. There is also provided one or more methods for constructing a tampon pledget having increased bypass leakage protection.Type: GrantFiled: December 2, 2010Date of Patent: February 16, 2016Assignee: Edgewell Personal Care Brands, LLC.Inventors: Robert Jorgensen, Keith Edgett
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Patent number: 9259361Abstract: An absorbent article has longitudinal side edges, transversal end edges, and an absorbent core. The absorbent core comprises a first absorbent layer having an opening and a fluid flow control structure between said first absorbent layer and a backsheet. An elastic member is arranged along each longitudinal side edge. The first absorbent layer has a longitudinal front portion, a longitudinal back portion and a narrow transversal transition located between said front and back portions. The width of the narrow transversal transition is 50-75% of the widest transversal width of the front portion, and 20-50% of the longitudinal length of the opening is located in the front portion. The front portion constitutes 20-40% of the total longitudinal length of the first absorbent layer. An interspace is located in an area between the elastic member and the first absorbent layer at least in an area laterally outside the narrow transversal transition.Type: GrantFiled: June 5, 2013Date of Patent: February 16, 2016Assignee: SCA HYGIENE PRODUCTS ABInventors: Charlotte Johansson, Susanne Fredrikson
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Patent number: 9259362Abstract: An absorbent article having a first containment flap and a second containment flap each having a stem, an inner flap projection, and an outer flap projection. The stems of the first and the second containment flaps can be positioned laterally inward of the longitudinal side edges of the absorbent article. The stem can extend away from the body facing liner when the absorbent article is in a relaxed condition. The inner flap projection can extend laterally from the stem towards a longitudinal axis of the absorbent article and the outer flap projection can extend laterally from the stem away from the longitudinal axis and the inner flap projection when the article is in a relaxed condition. The outer flap projection can be bonded to the stem in at least a portion of one of the front waist region and the rear waist region.Type: GrantFiled: May 22, 2013Date of Patent: February 16, 2016Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Robert Lee Popp, Scott Simon Craig Kirby, Rodney Allan Butler, Kylie Brooke Bridger, Jeffrey Alan DeBroux, David Fleger Bishop, Michael John Faulks
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Patent number: 9259363Abstract: An absorbent article is provided including a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet. The core defines a wearer facing side oriented towards a wearer when the article is being worn and an opposed garment facing side. The core includes a storage layer that also defines a wearer facing side and an opposed garment facing side. The core further includes a first core wrap sheet covering the wearer facing side of the storage layer, and a second core wrap sheet covering the garment facing side of the storage layer. The first core wrap sheet is joined to the second core wrap sheet along at least one stripe of juncture. The stripe of juncture extends in at least one of the transversal and longitudinal directions.Type: GrantFiled: June 17, 2013Date of Patent: February 16, 2016Assignee: The Procter & Gamble CompanyInventors: Peter Dziezok, Ralf Geilich
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Patent number: 9259364Abstract: A package of folded absorbent pants includes a housing portion with a front wall having a transparent window region. A plurality of absorbent pants are disposed within the housing portion. At least one of the pants is a display pant having a first folded configuration and being positioned within the housing portion to be at least partially visible through the transparent window region. A portion of the pants have a second folded configuration and are aligned in facing relation to define a first stack. The display pant is positioned within the housing portion such that the longitudinal direction of the display pant is aligned in a first direction and the first stack longitudinal direction is aligned in a second direction that is different than the first direction.Type: GrantFiled: December 12, 2013Date of Patent: February 16, 2016Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Patrick James Mickle, Sara Elaine Welch, Joseph Andrew Mlinar, Timothy John Kettenhofen, Erica Faye Creighton
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Patent number: 9259365Abstract: An absorbent article package, includes: a plurality of absorbent articles each folded to define a first outer face and a second outer face; and a packing bag that stores the plurality of absorbent articles in a layered state such that the first outer face of each of the plurality of the absorbent articles makes contact with the second outer face of an adjacent absorbent article, in which each absorbent article includes an engagement member arranged on the first outer face thereof and engaging with the second outer face of the adjacent absorbent article, and the packing bag includes a first face positioned to face the first or second outer faces of the absorbent articles stored in the packing bag and configured to form therein an opening to allow the absorbent articles to be extracted.Type: GrantFiled: June 1, 2012Date of Patent: February 16, 2016Assignee: UNICHARM CORPORATIONInventors: Daisuke Komatsubara, Takeshi Ikegami
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Patent number: 9259366Abstract: A disposable wearing article including a tape tab being capable of fix the used disposable wearing article by a simple handling. The disposable diaper includes a chassis, an absorbent structure attached to a skin-contact surface of the chassis and a tape tab attached to a non-skin-contact surface. The tape tab is attached to a rear waist sheet and folded back so as to define a first section, a second section and a third section. The first section is provided with a mechanical fastener which is substantially not retained on the second section. Outside in the longitudinal direction of a fastening portion provided with the mechanical fastener, first temporary joint spots for temporarily joining part of the first and second sections and second temporary joint spots for temporarily joining part of the first through third sections are provided.Type: GrantFiled: March 27, 2013Date of Patent: February 16, 2016Assignee: Unicharm CorporationInventors: Shunsuke Takino, Katsufumi Aoki
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Patent number: 9259367Abstract: A disposable absorbent article to be worn about the lower torso of a wearer that facilitates an easy, intuitive change is provided. The disposable absorbent article includes at least one serviceable indicium that facilitates an easy change by providing alignment of the article relative to an anatomical feature of the wearer or by externally highlighting one or more components of the article thereby indicating alignment and fit about the wearer's lower torso.Type: GrantFiled: July 16, 2013Date of Patent: February 16, 2016Assignee: The Procter & GambleInventors: Luke Robinson Magee, George Bartol Glackin, III, Christopher John Hosmer, Naomi Shoshana Korn, James Douglas Wilson, Mark Christopher Bates, Mattias Schmidt, Eva Susanne Dominique Thurnay, Joerg Mueller
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Patent number: 9259368Abstract: A patient transporter having sponsons that provide buoyancy when deployed on water is provided. A sponson assembly formed by two sponsons connected to each other by a material, and which can be positioned beneath a patient transporter to provide buoyancy, is also provided.Type: GrantFiled: March 14, 2014Date of Patent: February 16, 2016Assignee: Paper-Pak IndustriesInventors: Ronald Jensen, Richard Beu
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Patent number: 9259369Abstract: Powered patient support apparatuses—such as beds, cots, stretchers, or the like—include a plurality of user controls that allow a caregiver to control the steering and/or driving of one or more powered wheels from multiple different locations around the patient support apparatus (e.g. head end, foot end, and/or the sides). The control is carried out by force sensors that detect both an orientation of the applied forces and a magnitude of the applied forces. Translational and/or rotational movement is effectuated, depending upon the magnitude and direction of the forces, as well as the physical location of the applied force relative to a reference point on the support apparatus, such as the center. One or more object sensors may also be included in the support apparatus to assist in steering and/or navigating.Type: GrantFiled: March 12, 2013Date of Patent: February 16, 2016Assignee: Stryker CorporationInventors: Richard A. Derenne, Richard Thomas DeLuca, Thomas Joseph Newport, II, Kevin Mark Patmore
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Patent number: 9259370Abstract: A collapsible wheelchair (CW) may be relatively small and lightweight and may be adapted to be easily collapsed/folded into a callable faint, allowing for easy storage, transport and use. The CW may be adapted to be collapsed/folded and expanded/unfolded in a series of simple steps, executable with one hand, by a person in a seated position, allowing for independent use even by a user with limited physical capabilities. The CW may have a relatively small width, allowing for access into constricted spaces. The rear and interior space between its large wheels may be unobstructed, leaving an unobstructed inner width, allowing the CW to be maneuvered in reverse over standing objects, such as a standard toilet. The seat of the CW may be equipped with a trap door, to allow the use of a toilet while seated on the CW. The rim may be beneath the seat for cleanliness.Type: GrantFiled: January 26, 2012Date of Patent: February 16, 2016Assignee: Zriha Hlavin Industries Ltd.Inventors: Yoav Gabriely, Ruth Reuveni
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Patent number: 9259371Abstract: A siderail assembly comprises a siderail with a siderail body. The siderail body has a storage area integrated therein. The storage area has a bottom surface, at least one side surface, and an opening. The storage area is configured to removably retain at least one object therein.Type: GrantFiled: August 25, 2009Date of Patent: February 16, 2016Assignee: Hill-Rom Services, Inc.Inventor: Robert M. Zerhusen
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Patent number: 9259372Abstract: A pool access apparatus for moving a disabled person between a pool deck and a pool includes an arm supported for pivotal motion about a base axle and a seat supported for pivotal motion about a seat axle carried by the arm. A driver pivots the arm between a deployed position suspending the seat at least partially within the pool, and a stowed position suspending the seat in a position displaced laterally from the pool. The apparatus may include a chain-driven seat attitude maintenance linkage, an anchoring system comprising a sub-plate embedded in or disposed below the deck to which a base plate of the apparatus is removably connectable, and/or a wheeled portability kit that is removably connectable to the base plate.Type: GrantFiled: March 29, 2012Date of Patent: February 16, 2016Assignee: Global Lift CorporationInventors: Lee Steinman, Gary Steinman, Dale Steinman, Jeremy Steinman, Joshua Steinman
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Patent number: 9259373Abstract: A compression garment comprises a plurality of longitudinal wales arranged to form a fabric having a length and generally parallel to the length, and a plurality of secondary transverse elastomeric threads connecting adjacent longitudinal wales and equally spaced about a length of the longitudinal wales. In a stretched state, the longitudinal wales are spaced from one another and remain generally parallel to the length.Type: GrantFiled: February 3, 2014Date of Patent: February 16, 2016Inventor: Martin Winkler
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Patent number: 9259374Abstract: An assembly of a tub and liquid massage system, comprises a tub defining a bathing cavity for receiving liquid. A tub wall of the tub has a plurality of openings. A liquid massage system comprises a liquid circuit for collecting liquid from the tub, the liquid having at least a pump device for exposing the liquid in the liquid circuit to a pump action. A plurality of nozzles are provided at ends of the liquid circuit, each nozzle having a nozzle body with at least one connector portion in fluid communication with the liquid circuit. The nozzle body defines an outlet adapted to be mounted to a tub wall opposite one said opening in the tub wall for feeding liquid from the liquid circuit to the outlet into the bathing cavity of the tub, at least some of the nozzles having a throat portion in the outlet, the nozzles with the throat portion having an inner diameter reduction ratio between the nozzle body and the outlet of at least 2.5.Type: GrantFiled: April 24, 2013Date of Patent: February 16, 2016Assignee: C.G. AIR SYSTÈMES INC.Inventors: Miguel Castellote, Dominique Ciechanowski
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Patent number: 9259375Abstract: A prescription pill vial with dosage indexer is disclosed. The prescription pill vial includes a body having a sidewall and bottom forming an enclosure for prescription medications. The sidewall extends below the bottom forming a cavity beneath the enclosure. A rosette is on the bottom of the body. The rosette has a plurality of detents thereon. An indexer is configured to fit into the cavity and rotate therewithin. The indexer has a spring-biased pawl that engages the detents on the rosette, limiting the rotation of the indexer to a number of predefined positions corresponding to the detents on the rosette.Type: GrantFiled: November 19, 2013Date of Patent: February 16, 2016Inventor: Mark H. Miller
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Patent number: 9259376Abstract: The present invention relates to a process developed for production of a dry powder medicament used in respiratory tract diseases such as asthma and COPD.Type: GrantFiled: June 2, 2011Date of Patent: February 16, 2016Assignee: Sima Patent ve Lisanslama Hizmetleri Ltd. Sti.Inventor: Mahmut Bilgic
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Patent number: 9259377Abstract: Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.Type: GrantFiled: December 13, 2010Date of Patent: February 16, 2016Assignee: COLGATE-PALMOLIVE COMPANYInventors: Ben Gu, Mahmoud Hassan
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Patent number: 9259378Abstract: Disclosed is an emulsifier-free, skin-conditioning, cosmetic or dermatological preparation. The preparation is obtainable by a process which involves, inter alia, the dispersion of one or more polyacrylic acid polymers in water and the mixing of the resultant dispersion with a molten lipid phase without complete homogenization of the phases.Type: GrantFiled: July 23, 2013Date of Patent: February 16, 2016Assignee: BEIERSDORF AGInventors: Isabel Balcke, Sabine Schulz, Julia Eckert, Guido Heinsohn
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Patent number: 9259379Abstract: A oral care composition comprising a triple polymer system and a source of fluoride ions for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear is described. Such compositions are also of use in combating dental caries.Type: GrantFiled: June 28, 2013Date of Patent: February 16, 2016Assignee: Glaxo Group LimitedInventors: Ruth Corcoran-Henry, Soha Dattani, Christabel Fowler, Geeta Patel
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Patent number: 9259380Abstract: Agents for coloring and/or matting keratinic fibers, in particular human hair, include in a cosmetic carrier at least one specific substituted 1,4-diaminoanthraquinone derivative of formula (I), wherein the residues (R2, R4) mutually independently denote a grouping of formula (II). The cosmetic method of using these agents can be for producing intense blue shades and for matting keratin fibers.Type: GrantFiled: September 11, 2014Date of Patent: February 16, 2016Assignee: Henkel AG & Co. KGaAInventors: Antje Gebert, Astrid Kroos, Ralph Nemitz
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Patent number: 9259381Abstract: The invention relates to a cosmetic treatment method intended to stimulate hair growth, restore hair growth, and/or limit hair loss. The cosmetic treatment method includes providing a composition comprising at least one corn (Zea mays L.) peptidic hydrolyzate, as an active agent to stimulate hair growth, or reduce hair loss and applying it topically to an area having hair follicles.Type: GrantFiled: April 8, 2013Date of Patent: February 16, 2016Assignee: ISP INVESTMENTS INC.Inventors: Claude Dal Farra, Nouha Domloge, Jean-Marie Botto
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Patent number: 9259382Abstract: The present invention relates to a cosmetic composition comprising: a copolymer having a constituent unit corresponding to (A) a vinyl monomer having a carboxyl group in a structure and a constituent unit corresponding to (B) a vinyl monomer represented by the following formula (1); a cationic surfactant; a higher alcohol; and a silicone oil: CH2?C(R1)—CO—X-(Q-O)r—R2??(1) wherein R1 is a hydrogen atom or a methyl group; R2 is a hydrogen atom or an alkyl group having a carbon number of 1 to 5, each of which may have a substituent; Q is an alkylene group having a carbon number of 2 to 4, which may have a substituent; r represents an integer of 2 to 15; and X represents an oxygen atom or NH, and the number of atoms bonded linearly to each other in the structure of -(Q-O)r—R2 is 70 or less.Type: GrantFiled: April 22, 2013Date of Patent: February 16, 2016Assignee: MITSUBISHI CHEMICAL CORPORATIONInventors: Akira Ishikubo, Shoya Yoda
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Patent number: 9259383Abstract: The present invention provides a colouring pre-mix for use in colouring of a cosmetic composition and a coloured cosmetic composition including the same, wherein the colouring pre-mix includes 45-80 wt-% benzyl benzoate; 20-49 wt-% dipropylene glycol; 0.00001-5 wt-% colouring plant extracts; and optionally 0.00001-5 wt-% colorants; with the provision that the content of benzyl benzoate exceeds the content of dipropylene glycol, wherein all data given in wt-% refer to the total weight of the colouring pre-mix.Type: GrantFiled: February 27, 2013Date of Patent: February 16, 2016Assignee: COTY INC.Inventors: Rupali A. Kulkarni, Ralph Macchio, Leslie C. Smith
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Patent number: 9259384Abstract: The present invention relates to ionic compositions for enhancing wound healing, particularly in the sinonasal cavity. The ionic components of the composition can include potassium, calcium, rubidium, zinc, bromide, and magnesium in an isotonic solution. In other embodiments, the ionic components of the composition can include magnesium, bromide, sulfate, sodium, and chloride. Methods of enhancing wound healing, enhancing sinonasal mucosal healing, promoting mucosal reciliation, and debriding tissue by administering the compositions of the present invention are also presented.Type: GrantFiled: January 23, 2014Date of Patent: February 16, 2016Assignee: RED OAX HOLDINGS, LLCInventor: Kevin Powers
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Patent number: 9259385Abstract: The present invention relates to ionic compositions for enhancing wound healing, particularly in the sinonasal cavity. The ionic components of the composition can include potassium, calcium, rubidium, zinc, bromide, and magnesium in an isotonic solution. In other embodiments, the ionic components of the composition can include magnesium, bromide, sulfate, sodium, and chloride. Methods of enhancing wound healing, enhancing sinonasal mucosal healing, promoting mucosal reciliation, and debriding tissue by administering the compositions of the present invention are also presented.Type: GrantFiled: January 23, 2014Date of Patent: February 16, 2016Assignee: RED OAX HOLDINGS, LLCInventor: Kevin Powers
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Patent number: 9259386Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.Type: GrantFiled: June 29, 2012Date of Patent: February 16, 2016Assignee: RANI THERAPEUTICS, LLCInventor: Mir Imran
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Patent number: 9259387Abstract: A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer.Type: GrantFiled: May 18, 2015Date of Patent: February 16, 2016Assignee: INTEC PHARMA LTD.Inventors: Nadav Navon, Eytan Moor, David Kirmayer, Elena Kluev, Giora Carni
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Patent number: 9259388Abstract: The invention relates to a method for treating overactive bladders and a device for storing and administering non-occluded oxybutynin topical compositions.Type: GrantFiled: October 22, 2013Date of Patent: February 16, 2016Assignee: Watson Pharmaceuticals, Inc.Inventors: Scott Gochnour, Venkatesh Subramanyan, Michael W. Kimball
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Patent number: 9259389Abstract: The present invention concerns a pharmaceutical formulation intended for oral administration containing a synthetic oligosaccharides containing one to 18 monosaccharide units and having a therapeutical activity or a pharmaceutically acceptable additions salt or solvate thereof wherein the formulation contains: a) the synthetic oligosaccharide (A) in an amount of up to 5% by weight of the total weight of the formulation, advantageously up to 1% by weight of the total weight of the formulation, b), a lipophilic phase (B) consisting of triglyceride of fatty acids in an amount of 50 to 80% by weight of the total weight of the formulation, advantageously of 50 to 70% by weight of the total weight of the formulation, c) at least one lipophilic surfactant (C) with HLB below 7 consisting of partial esters of polyol and fatty acids in an amount of 10 to 30% by weight of the total weight of the formulation, advantageously of 15 to 30% by weight of the total weight of the formulation, d) at least one hydrophilic surfactType: GrantFiled: December 17, 2010Date of Patent: February 16, 2016Assignees: ENDOTIS PHARMA, CATALENT FRANCE BEINHEIM SAInventors: Julien Meissonnier, Nathalie Sicre, Guillaume Sabate, Guy Dubreucq, Vanessa Nancy-Portebois, Maurice Petitou
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Patent number: 9259390Abstract: Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation.Type: GrantFiled: July 24, 2008Date of Patent: February 16, 2016Assignee: The University of Houston SystemInventors: Diana Shu-Lian Chow, Pranav Gupta, Yulan Qi, Dong Liang
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Patent number: 9259391Abstract: Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation.Type: GrantFiled: June 10, 2010Date of Patent: February 16, 2016Assignee: The University of Houston SystemInventors: Diana Shu-Lian Chow, Pranav Gupta, Yulan Qi, Dong Liang
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Patent number: 9259392Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.Type: GrantFiled: September 27, 2013Date of Patent: February 16, 2016Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
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Patent number: 9259393Abstract: The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.Type: GrantFiled: November 13, 2001Date of Patent: February 16, 2016Assignee: Aptalis Pharma S.R.L.Inventor: Mario Maio
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Patent number: 9259394Abstract: A dosage form comprising a tablet core containing at least one active ingredient and having at least one modified release coating that partially surrounds the tablet core is disclosed. The tablet core is preferably in the form of a compressed core wherein the at least one modified release coating is provided on a position of the exterior surface of the compressed core using dipping technology. The invention also relates to a method of manufacturing the dosage form and a method of treatment using the dosage form.Type: GrantFiled: December 7, 2010Date of Patent: February 16, 2016Assignee: Johnson & Johnson Consumer Inc.Inventors: Saumitra Bagchi, Murali Vuppala
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Patent number: 9259395Abstract: A tumor-targeting gas-generating nanoparticle, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same relate to a tumor-targeting gas-generating nanoparticle including a polycarbonate core and a amphiphilic coat, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same. Since a tumor-targeting gas-generating nanoparticle according to the present disclosure is accumulated in the tumor tissue in large quantity and generates strong ultrasound wave signals, it can be usefully used as a contrast agent for ultrasonic imaging.Type: GrantFiled: May 31, 2013Date of Patent: February 16, 2016Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Ick Chan Kwon, Kwang Meyung Kim, Kuiwon Choi, Heebeom Koo, Hyun Su Min, Inchan Youn
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Patent number: 9259396Abstract: The present invention relates to a method of preparing a solid form of soy isoflavone (e.g. genistein). In particular, the present invention relates to a method of preparing a solid form of soy isoflavone by precipitation with compressed antisolvent using a supercritical fluid to produce nano-sized particles of soy isoflavone with an improved dissolution rate and bioavailability. An oral composition or aerosolized formulation comprising the nanoparticles of the soy isoflavone prepared by the method of the present invention is also disclosed herein. The dissolution rate and bioavailability of the nanoparticles of the soy isoflavone prepared by the method of the present invention have a 2-fold increase and a 2.6-fold increase respectively as compared to those of the raw soy isoflavone.Type: GrantFiled: January 4, 2013Date of Patent: February 16, 2016Assignee: NANO AND ADVANCED MATERIALS INSTITUTE LIMITEDInventors: Kathy Qian Luo, Jinjie Xu