Abstract: The present invention relates to the field of instruments for imaging internal structures of the human body, and in particular of the eye. More specifically it relates to an optimized method and an optical coherence tomography system thereof.

Abstract: An optical measuring device is provided. An actuator of a reference mirror set drives a reference mirror to move back and forth at a scan velocity. A first light source module transmits a first light beam to an optical coupling module transmitting two parts of the first light beam respectively to an examinee object and the reference mirror set. The first light beam then is reflected by the examinee object and reference mirror set and then transmitted to the optical coupling module and the processing unit. The second light source module transmits a second light beam to the examinee object. Then the second light beam is reflected and then transmitted to the second sensing unit. The second sensing unit provides a sensing signal to the processing unit which accordingly provides a value of the relative velocity. The thickness is calculated according to the relative velocity and the scan velocity.

Abstract: An optical coherence tomographic imaging apparatus includes a movement amount acquisition unit configured to acquire the amount of subject's eye movement based on a plurality of images of the subject's eye acquired at different times, a determination unit configured to determine whether the amount of subject's eye movement before a scan by the scanning unit exceeds a threshold value, and a control unit configured to, in a case the amount of subject's eye movement before the scan is equal to or smaller than the threshold value, control the scanning unit to perform scanning position correction between a scan and the next scan based on the amount of movement.

Abstract: Ocular fundus inspection apparatus (10) having a frame (11) provided with references for the positioning of at least one of the patient's eyes in an inspection position, and an inspection unit (100) fixed to the frame (11) and comprising: a first optical unit (12) having an optical axis incident in correspondence of the inspection position references; an image detecting device (13); a second optical unit (14), for the focusing, having an optical axis incident on the detecting device (13), in said inspection unit (100) being defined an optical path between the first optical unit (12) and the detecting device (13; a first lighting unit (15) for projecting a focusing pattern, for focusing the ocular fundus on said detecting device (13), the focusing pattern being formed by an infrared radiation. The first lighting unit (15) emits the focusing pattern from a first emission position.

Abstract: Provided is a slit lamp microscope capable of controlling irradiation of slit light and background illumination light interlockingly. Embodiment includes a main illumination system, background illumination system, observation system and controller. The main illumination system includes a first light source unit that outputs first light and slit forming unit that forms a slit with changeable width, and illuminates an eye with the first light having passed through the slit. The background illumination system includes a second light source unit that outputs second light, and illuminates a peripheral area of an eye area irradiated with the first light. The observation system includes an eyepiece lens, imaging device, and group of optical elements that guides reflected light of the first light and reflected light of the second light from the eye to the eyepiece lens and imaging device. The controller interlockingly controls the main illumination system and second light source unit.

Abstract: A device adapter is used to mount a handheld device, such as a smartphone, to the binocular tube of a microscope, such as a slit lamp. The handheld device has a camera, a device surface on one side, and a camera lens at the one side. The adapter includes a body with an abutment surface, two side grippers and a lower gripper used to secure the device against the abutment surface of the body. The device adapter also includes an adapter assembly including a camera lens opening alignable with a handheld device camera lens so that an image entering the outer end of the ocular tube with integrated optics passes through the ocular tube, through the integrated optic, and through the camera lens opening for passage into the camera lens.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin or a patient or the surface of a structure such as a building or a bridge.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

Abstract: Medical monitoring devices may be able to read a wireless tag and determine an identity of a patient wearing the tag based on the information read from the tag. The tag may be an RFID tag, a barcode, etc. The tag may itself include identifying information for the patient, or the tag may include an identifier that allows the patient information to be retrieved from a remote storage device via a network. The medical monitoring device may also be able to retrieve configuration information using the identifier. The configuration information may include settings for the medical monitoring devices and/or may include destinations for physiological data measured by the medical monitoring devices. Destinations may organize data based on the patient and may use the patient identifiers transmitted by the medical monitoring devices to associate data from separate medical monitoring devices attached to the same patient.

Abstract: A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.

Abstract: An optoacoustic imaging device has a light source module which irradiates a tested object with light, a light source driver which drives and controls the light source module, a detector which detects an optoacoustic wave generated inside the tested object as a result of the tested object being irradiated with the light, an image generator which generates still image information based on a detection signal from the detector, and an acquirer which acquires an organ pulsation signal. The organ pulsation signal is used as a trigger to make the light source driver drive the light source module and to make the image generator generate the still image information.

Abstract: A method and apparatus for depth profiling the structure of a subsurface region of skin, in particular burned skin, wherein the method/apparatus comprises directing laser light at an absorbing target to generate ultrasonic sound waves, which are used to determine the sound speed in the skin, and using the determined sound speed in conjunction with two-wavelength photoacoustics to depth profile of the structure of the subsurface of the skin.

Abstract: There is provided a method for measuring the blood pressure of a subject, comprising receiving an acoustic signal comprising an electronic representation of sounds generated by a hemodynamic effect of the subject's heart beats on one or more blood vessels in a body part of a subject; deriving one or more parameters from the received acoustic signal; and calculating a blood pressure value based on the one or more derived parameters.

Abstract: A vascular viscoelasticity evaluation device and method in which, a pulse wave obtained using a cuff is subjected to first derivation, a positive amplitude peak value Vf1 that occurs first and a negative amplitude peak value Vr2 that occurs second out of a plurality of negative amplitude peak values are detected in a state in which an external force substantially the same as or greater than the systolic blood pressure has been exerted on a blood vessel, and a ratio of the positive amplitude peak value Vf1 that occurs first to the negative amplitude peak value Vr2 that occurs second is calculated, and then the vascular viscoelasticity is evaluated on the basis of this calculated ratio.

Abstract: The invention relates to a method for estimating blood loss from a sample of fluid collected during surgery. The method includes utilizing spectrophotometric analysis to determine a hemoglobin proportion within the sample, and estimating a patient's total blood loss based upon the analysis and known proportions of hemoglobin mass to blood volume.

Abstract: Devices and systems for continuous monitoring of the heart rate of a patient diagnosed with or at risk of heart diseases. Wireless communication technologies such as radio frequency identification (RFID), Bluetooth and WiFi are integrated into a heart rate monitoring device to connect it to a communication device, the patient's database at a healthcare institution and to trigger an automatic call for emergency services through the communication device when emergency medical attention is needed.

Abstract: A biological information detecting device includes a first detection unit detecting biological information of a user, an abnormality determination unit determining whether or not an abnormality occurs in the user on the basis of the biological information detected by the first detection unit, and a frequency change unit changing a detection frequency of the first detection unit to a second frequency higher than a first frequency when the occurrence of the abnormality is determined by the abnormality determination unit.

Abstract: A patient vital sign monitoring system comprises a frame, a bar code list and a vital sign monitor. The vital sign monitor uses a bar code reader to reads measurement bar codes or function-setting bar codes of the bar code list and generates an action instruction corresponding to a measurement instruction of one measurement bar code or a function-setting instruction of one function-setting bar code to a control unit of a host computer module. According to the action instruction, the control unit triggers an optional vital sign measurement unit to undertake the selected vital sign measurement and transmit the result to a database, or sets a function of the vital sign monitor. The patient vital sign monitoring system is easily transported to and flexibly applied to different wards, avoiding inaccuracy of manual transcription and errors in the transfer process, and saving the time the nursing personnel spend in transcription.

Abstract: Provided is a film-type biomedical signal measuring apparatus configured in a such a way that a plurality of metallic thin film electrodes and a circuit unit are formed on a film-type piezoelectric element so as to easily attach the apparatus to the skin and an electrical signal as well as an electrical signal of a human body is simultaneously measured using the plurality of metallic thin film electrodes and the circuit unit. Accordingly, the film-type biomedical signal measuring apparatus simultaneously measures electrocardiogram (ECG) and ballistocardiogram (BCG) from the simultaneously measured electrical signal and vibration signal of the human body and extracts biomedical information of various types of health indexes such as a heart rate, a stress index, BCG, a blood pressure, an amount of physical activity, a respiration rate, and VO2max from the two different biomedical signals.

Abstract: An algorithm for determining heart rate by removing motion artifacts from a PPG signal in the frequency domain utilizes a principal component analysis. Some examples of the present disclosure process PPG signals in combination with accelerometer signals to remove unwanted artifacts in the frequency domain. For example, principal components of the accelerometer signal can be generated and combined with the PPG signal to filter out acceleration contributions represented in the PPG signal to reveal heart rate peaks. Additionally, in some examples, templates may be stored for correlation with candidate heart rate peaks to select those peaks with the highest correlations with the stored templates.

Abstract: An algorithm for removing motion artifacts from a PPG signal in the frequency domain and a harmonic template classifier (HTC) algorithm and unit to determine heart rate are disclosed. In some examples, PPG signals can be processed in combination with accelerometer signals to remove unwanted artifacts in the frequency domain. For example, an acceleration mask can be generated and used to filter out acceleration contributions represented in the PPG signal. Additionally or alternatively, in some examples, an HTC unit can be configured to generate a heart rate correlation curve based on the correlation between frequency domain PPG signals and spectral templates. In some examples, the HTC unit can be configured to implement an algorithm to determine a predicted heart rate and an associated confidence measure. In some examples, heuristics can be used to determine a predicted heart rate based on the correlation curve and/or the confidence measure.

Abstract: A medical device system for monitoring a patient's heart includes an implantable medical device (IMD) configured to determine sensing vector data for multiple sensing vectors selected from electrodes coupled to the IMD. The system further includes an external device configured to receive the sensing vector data and provide at least a portion of the sensing vector data to a user display configured to display sensing vector criteria and the sensing vector data as part of a graphical user interface for programming a sensing vector used by the implantable medical device for monitoring a patient's heart rhythm.

Abstract: This invention relates to the determination and/or representation of physiological information relating to a heart surface.

Abstract: The invention relates to a method for estimating the brain activity, from physiological signals, in particular magnetoencephalographic or electroencephalographic surfaces, which has, in certain predetermined areas of the cortex, considered as areas of interest, an improved accuracy with respect to other areas of the gridding. It enables a more accurate estimation to be obtained in the areas of the brain intended to be subjected to a particular treatment, for example to accommodate cortical electrodes.

Abstract: The invention relates to a method for estimating the electrical activity of a tissue using a plurality of sensors, in particular the brain activity related to a motor task performed, imagined, or visualized by a subject, using a plurality of magnetoencephalographic or electroencephalographic sensors, when this subject is submitted to a stimulus. The estimation method is based on an MNE criterion in which the coefficients of the covariance matrix of the physiological signals acquired by the different sensors are weighted using the correlation coefficients of these signals with a signal representative of the stimulus.

Abstract: Systems and method for classifying EEG signals of a human subject generated responsive to a series of images containing target images and non-target images. The EEG signals are in a spatio-temporal representation. The time points are classified independently, using a linear discriminant classifier, to compute spatio-temporal discriminating weights that are used to amplify the spatio-temporal representation, to create a spatially-weighted representation. Principal Component Analysis is used on a temporal domain for dimensionality reduction, separately for each spatial channel of the signals, to create a projection, which is applied to the spatially-weighted representation onto a first plurality of principal components, to create a temporally approximated spatially weighted representation.

Abstract: A probe including a first sensor having a first magnetometer and a first accelerometer and a second sensor having a second magnetometer and a second accelerometer is configured for determining the distance and direction to a marker. The marker may be magnetic and may be surgically inserted into a patient's body to mark a specific location. The probe may be used to locate the marker, thus identifying the location. The probe may include a microprocessor that receives an output from the first sensor and an output from the second sensor and determines the distance and direction to the marker.

Abstract: The invention features an apparatus for producing a fluid stream having plurality of nanoparticles in the fluid stream. The apparatus includes a source configured to provide a fluid stream having a first randomly sized distribution of a plurality of nanoparticles; a flow control zone configured to receive the fluid stream from the source and to control the fluid stream to produce a controlled fluid stream having a selected flow rate; a separation zone configured to receive and to separate the selectively controlled fluid stream into at least one separated fluid stream having a non-randomly sized distribution of nanoparticles; and a collection zone capable of receiving the separated fluid stream according to at least one non-random sized distribution of nanoparticles to produce at least one collected stream. The apparatus is configured for a continuous flow of the fluid stream.

Abstract: A portable telemetry device includes a physiological component, a movement component, a wireless radio, and a communication component. The physiological component is configured to receive, from at least one sensor, physiological data representative of a physiological condition of a patient. The movement component is configured to detect movement of the portable telemetry device and generate movement data. The portable telemetry device is configured to attach to the patient. The wireless radio is configured to wirelessly send radio signals. The communication component is configured to transmit the physiological data and the movement data to a monitoring system using the wireless radio.

Abstract: A system and method for efficiently and accurately classifying user activity. In a non-limiting example, accelerometer signals and/or gyroscope sensor signals may be analyzed to classify user activity, for example, that of a user of a handheld and/or wearable device. Information from additional sources and sensors (e.g., other inertial sensors, non-inertial sensors, passive sensors, etc.) may also be utilized.

Abstract: A real-time human activity recognition (rtHAR) engine embedded in a wearable device monitors a user's activities through the wearable device's sensors. The rtHAR uses the signals from the sensors to determine where the wearable device is relative to the user's body, and then determines the type of activity the user engages in depending upon the location of the wearable device relative to the user's body. The rtHAR is preferably installed on the wearable device as an embedded system, such as an operating system library or a module within software installed on the wearable device, so as to improve the quality of direct feedback from the wearable device to the user, and to minimize the amount of data sent from the wearable device to external archival and processing systems.

Abstract: Biometric monitoring devices, including various technologies that may be implemented in such devices, are discussed herein. Additionally, techniques for utilizing gyroscopes in biometric monitoring devices are provided. Such techniques may, in some implementations, involve obtaining swimming metrics regarding stroke cycle count, lap count, and stroke type. Such techniques may also, in some implementations, involve obtaining performance metrics for bicycling activities.

Abstract: A bloodless glucose measuring and monitoring device which comprises a main computer and a PCB with a LCD display; a microprocessor; a blood glucose detection circuit connected to the microprocessor which includes a blood glucose detection module; and a memory module, a power module and a timekeeping module connected to the microprocessor. The PCB comprises a body resistance acquisition circuit with a body resistance acquisition module electrically connected to the microprocessor for measuring a body resistance between two points of skin of a human body and communicates with the microprocessor such that the body resistance obtained by the body resistance acquisition module is translated into a blood glucose value through the microprocessor and then the blood glucose value is displayed through the LCD display of the main computer.

Abstract: A device is described for interrogating human skin using tight coupling between the transmitter and receiver of the millimeter waves (MMWs). Methods are provided to evaluate changes in the amplitude and/or phase of the transmitted MMWs in order to estimate the blood concentration of glucose. Using this device and the related methods, the blood glucose concentration or a change in the blood glucose concentration can be monitored for diagnosing diabetes mellitus and other metabolic disorders of carbohydrate metabolism characterized by either high blood glucose level (hyperglycemia) or low blood glucose level (hypoglycemia), as well as for monitoring (including self-monitoring) a metabolic disorder progression or an efficacy of treatment.

Abstract: According to various embodiments, a regional oximetry sensor may include a light emitting element configured to emit light, a light detector configured to receive the light, and a memory device configured to store a baseline. The baseline stored by the memory device enables a regional oximetry monitor to display the baseline on a display of the regional oximetry monitor.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: An apparatus for performing phlebotomy through a peripheral intravenous line. The apparatus includes an introducer and a catheter configured to advance the catheter through a peripheral intravenous line. A y-adapter with a port of larger diameter is configured to receive the catheter and place in fluid communication with the peripheral intravenous line. When advanced the catheter is configured to transport a bodily fluid (i.e. blood) to a volume outside of the body.

Abstract: Provided is an apparatus and method of measuring stress. The apparatus includes: a light source configured to emit light to the subject; a sensor configured to measure light reflected from the subject; a data extractor configured to obtain, from the reflected light, data that indicates at least one object material included in the subject; and a data processor configured to generate information about the stress of the subject based on a correlation between the obtained data and a reference value of stress.

Abstract: Fluid/urine monitoring devices and/or systems are provided for monitoring fluid output, including volume and flow rate. One high resolution, low cost electronic urine monitoring device and system collects urine and includes a capacitance sensor. The capacitance of the capacitance sensor may be correlated with fluid content and be used to identify urine volume and flow rate. Another high resolution, low cost flow meter is placed in line with drainage tubing and uses a capacitance sensor to measure fluid output without collecting the fluid. Other low cost urine monitoring devices use pressure based or weight based measurement sensors to measure volume and flow rate.

Abstract: This invention provides a dynamic urine monitor. The dynamic urine monitor comprises a case, inside which is equipped with a urine collection device, a pipeline for flowing the urine into the urine collection device, and a measurement system for dynamically measuring the urine. The measurement system comprises a weight measurement subsystem, a density measurement subsystem, and an outlet-inlet module. The weight measurement subsystem comprises a weight sensor and a weight information ADC; the weight sensor dynamically measures the urine weight of the urine collection device. The density measurement subsystem comprises a density sensor and a density information ADC. The density sensor dynamically measures the urine density and it is serially connected with the upstream pipeline of the urine collection device. The outlet-inlet module is used to exchange the information of the weight information ADC and with density information ADC with outside.

Abstract: A system and method provides for calculating brain volume in a patient. The method and system includes receiving current intracranial volume data of a patient after a brain injury event and electronically calculating a current brain volume of the patient based on the current brain volume data. The method and system therein electronically calculates a prior brain volume based at least on the current brain volume data and prior age of the patient, the prior brain volume and age being at an earlier point in time, such as prior to a brain injury. The method and system further determines a brain volume change value based on a comparison of the current brain volume and the prior brain volume.

Abstract: Systems and techniques for detecting and monitoring for traumatic brain injury and recovery are described. A system can include a photoplethysmography (PPG) system with a robust PPG sensor and a monitoring system with a detection and monitoring module. The detection and monitoring module, when executed, directs the monitoring system to: extract a pulse rate waveform from a signal from the PPG system containing information about a patient's heart; determine a pulse rate variability for the pulse rate waveform; and compare the pulse rate variability to a reference to determine a brain injury status.

Abstract: An apparatus for noninvasively measuring a bio-analyte including a metering device configured to obtain at least one of light and electrical information representative of an amount of fibrous protein from skin of a subject; and a processor configured to determine information representative of an amount an analyte present in blood of the subject based on the obtained information representative of an amount of the fibrous protein.

Abstract: A method is described that makes it possible to measure flushing, particularly in the context of the study of rosacea, and to distinguish normal flushing from pathological flushing. Also described, is the use of said method to study the effect of drug candidates, particularly against rosacea. The method can include: a) subjecting the subject to a flushing inducing stimulus; b) measuring the inflow of blood in the face of the subject during a time period covering the flushing; and c) calculating entropy of the inflow of blood.

Abstract: Device (1) for assessing, preventing and treating LBP, which comprises: six units (100a, 100b, 100c, 100d, 100e, 100f), each unit comprising: an EMG acquisition subsystem (30a); connecting means (10a-20a, 10b-20b, 10c-20c, 10d-20d, 10e-20e, 10f-200 for connecting the EMG acquisition subsystem (30a) to a pair of electrodes attached to a patient's skin, such that each unit receives the surface EMG signals of a specific muscle group of the patient; and, a actuator (60a) for providing haptic stimulus to said muscle group; a muscular activity pattern recognition and feedback subsystem (200, 500); the device further comprising: a wearable garment (300, 301, 302) with a central portion (300e) to which the second and fifth units (100b, 100e) are attached parallel to each other; and a set of four straps (300a, 300b, 300c, 300d) to which ends are attached the first, third, fourth and sixth units (100a, 100c, 100d, 100f) at 45°, 135°, ?135° and ?45°, respectively, with respect to the second and fifth units (100b

Abstract: A gesture recognition biofeedback device is provided for improving fine motor function in persons with brain injury. The system detects a physical characteristic of the patient and provides feedback based on the detected characteristic. For instance, the system may detect surface muscle pressures of the forearm to provide real-time visual biofeedback to the patient based on a comparison of the detected muscle pressure and predefined values indicative of appropriate motor function.

Abstract: Systems and methods for providing a sleep recommendation include providing a sleep recommendation using an earphone with a biometric sensor. The system includes a preferred sleep determination module that determines a preferred sleep duration. The system also includes a sleep debt module that creates and updates a sleep debt based on the preferred sleep duration and an actual sleep duration. In addition, the system includes a sleep recommendation module that provides a recommended sleep duration based on the sleep debt.

Abstract: A system for creating and dynamically updating a user activity profile includes an earphone, a processor, a sensor module, a memory module. The memory module includes stored computer program code that, along with the memory module and the processor, is configured to carry out a number of operations to create and dynamically update the user activity profile. One such operation involves maintaining an activity archive that includes activity information received from the sensor module and that is representative of a user's activity. Another such operation includes creating and updating a dynamic activity profile based on initial user input and further based on the activity archive. The initial user input contributes to the dynamic activity profile according to a first weighting factor, and the activity archive contributes to the dynamic profile according to a second weighting factor.

Abstract: A wearable medical device and method of detecting clipping of ECG signals is disclosed. In one embodiment, the wearable medical device comprises a plurality of ECG sensing electrodes configured to sense an ECG of a patient and an ECG acquisition circuit electrically coupled to a pair of the plurality of ECG sensing electrodes and configured to provide an amplified and conditioned analog ECG signal, a programmable attenuation/gain stage electrically coupled between a first gain stage and a second gain stage, an ADC electrically coupled to the ECG acquisition circuit to receive and digitize the amplified and conditioned analog ECG signal and provide a digitized ECG signal, and a signal conditioning to and control unit electrically coupled to the ECG acquisition circuit and the ADC to receive and monitor the digitized ECG signal and to detect clipping of the amplified and conditioned analog ECG signal based upon the digitized ECG signal.