Abstract: A wound closure system and method having a porous pad for providing a reduced pressure to a tissue site is disclosed. The porous pad comprises a porous material formed by spraying a chemical substance that cures to form the porous material which has a body and an outer surface. Both the body and the outer surface have pores wherein the average size of the pores in the outer surface is smaller than the average size of the pores in the body. The porous pad further comprises a pathway formed within the porous material that is adapted to fluidly communicate with a source of reduced pressure.

Abstract: A wearing article (1) of the invention has edge sections (leg edge sections and waist edge section) configured including sheets. On the sheets in the edge sections, elastic members (6, 7, 8) are disposed in their stretched state along the edge sections. Draw-processed sections (P1, P2) are formed by performing draw processing, in the stretching direction of the elastic members (6, 7, 8), on the disposition sections of the sheets where the elastic members (6, 7, 8) have been disposed. Furthermore, a draw-processed section (P3) is formed by performing draw processing, in the stretching direction of an elastic member (5), on the disposition section of a band-shaped sheet (15), which configures three-dimensional gathers (18), where the elastic member (5) has been disposed.

Abstract: Sanitary articles (1) that can be worn as a pair of pants, said articles (1) comprising a central body (2), which can be set around the crotch region of the user, said central body (2) extending m a longitudinal direction (X1) between two opposite ends, and at least one pair of side panels (3), which are connected to one of the ends of the central body (2) and extend on opposite sides of said central body (2) to define at least in part the waistband of the article (1). The side panels (3) are connected to the central body (2) while they are in a folded condition. The aforesaid panels are preferentially obtained in a folded condition, with the distal edge (7) set in the proximity of the proximal edge (6).

Abstract: A feminine hygiene product including a tampon, an absorbent pad, and a string connecting the tampon to the absorbent pad is disclosed. The string can include at least one breakable section, or the string may releasably affixed to the absorbent pad. The tampon and/or the absorbent pad can be formed from cotton, rayon, or a cotton-rayon mixture. The feminine hygiene product can further include an applicator sized to accommodate the tampon and the absorbent pad, and to facilitate deployment of the same.

Abstract: A liquid detection system includes an absorbent article for personal wear having a liquid permeable liner, an outer cover, and an absorbent body disposed between the liner and the outer cover. The article also includes at least one graphic element, a conductive pattern at least partially superposed with the graphic element, and a barrier layer disposed between the graphic element and the conductive pattern. A non-invasive signaling device is selectively attachable to the outer cover of the absorbent article in overlying relationship with the conductive pattern. The signaling device is adapted to detect the presence of liquid within the absorbent article.

Abstract: An absorbent article includes a liquid-permeable top sheet, a liquid-impermeable back sheet, and an absorbent body between the liquid-permeable top sheet and liquid-impermeable back sheet. The top sheet exhibits a color difference in a range of 37-80, based on the L*a*b* color system and measured from a skin contact surface of the top sheet in a liquid dropping test. Further, the top sheet has a color-reducing agent having an IOB of 0.00-0.35, a melting point of no higher than 45° C. and a water solubility of 0.00-0.05 g in 100 g of water at 25° C. The absorbent article is configured to allow a user to visually confirm reduction in residue of highly viscous menstrual blood on the top sheet after its absorption, thereby providing reassurance to the user.

Abstract: A reusable pad, such as those intended for protection during menstrual periods, is provided that includes an inner layer made of two layers of natural cellulose fabric, the layers of natural cellulose fiber bonded together by a biodegradable polyurethane film. Two intermediate layers of absorbent organic bamboo fabric are also provided, along with an outer cover formed by a fabric made from cotton. The inner layer is inserted between the two intermediate layers to form a composite, and the composite is inserted into the outer cover.

Abstract: A protective undergarment includes a sling that is suspended from an outer shell. The sling forms a pocket in which a reusable or disposable absorbent pad can be positioned. The sling has arcuate, stitched end edges at both the front and the rear of the sling. The garment thus fits better will less chance that portions of the sling at opposite ends of the pocket will be exposed to moisture. The sling can also be attached to and detached from the garment by using hook and loop fasteners that can be partially covered so that abrasive corners are not exposed. The same overlying layers can be used on tabs for securing the protective undergarment around the waist.

Abstract: A stretch laminate includes a first layer including an elastomer film, the first layer having a surface, and a second layer including a nonwoven material, the second layer having a surface that is attached to the surface of the first layer. The tensile behavior in the transverse direction of the stretch laminate is within about 2.5 N/cm of the tensile behavior in the transverse direction of the film at an engineering strain of about 1.5, and exists independent of mechanical activation. A method of making the stretch laminate and an absorbent article having at least one region defined by the stretch laminate are also provided.

Abstract: The present invention is directed to a disposable absorbent article. The disposable absorbent article has a longitudinal centerline, a lateral centerline, an outer surface and an inner surface. The absorbent article is folded before use along the lateral direction. The disposable absorbent article comprises a liquid pervious topsheet, a liquid impervious backsheet, an absorbent core disposed therebetween, and an elasticized outer leg cuff. The elasticized outer leg cuff is disposed adjacent to a longitudinal side edge of the absorbent article. The elasticized outer leg cuff has a base and a gasket cuff supported by the base at a joint of the base to the gasket cuff. The gasket cuff is provided with elasticity and has a top gasket cuff surface, an inner cuff extending laterally inwardly from the joint and an outer cuff extending laterally outwardly from the joint.

Abstract: A method of forming disposable absorbent articles includes forming at least two different types of absorbent articles on a single product line. Each type of absorbent article has an absorbent structure that differs from the absorbent structure of at least one other absorbent article type on the product line. The method further includes creating a visual distinction between the different types of absorbent articles and packaging the different types of absorbent articles in a single package.

Abstract: A water resistant protective body cover including a trapezoidal water resistant cover, an air chamber continuously attached to a top edge of the cover, a hand pump attached to the air chamber, and a pair of interconnectable hook and loop fastener strips including a first strip and a second strip. The first strip is continuously disposed on an exterior surface of a right edge of the cover. The second strip is continuously disposed on an interior surface of a left edge of the cover.

Abstract: A low-gear drive system functionally coupled to a wheelchair is provided herein.

Abstract: A foldable scooter frame includes: a front fork pivoted to a front frame, a front wheel assembly disposed on the front fork, the front fork being fixed to a pivot seat of a control unit, the pivot seat being pivoted to a control rod, a rear frame being connected to the front frame in a foldable manner, a rear wheel assembly disposed on the rear frame. With the pivoting arrangement of the front and rear frames, and more importantly, with the bridge rod abutted against the rear frame, the foldable scooter frame of the present invention can be maintained in a best stable state when in use, and when folded, the distance between the front and rear wheel assemblies can be reduced to the least possible amount, and the whole structure is simply structured and can be easily folded without requiring the use of complicated linkage mechanism.

Abstract: An anti-tip system is provided for improving the stability of a powered vehicle, such as a powered wheelchair. The vehicle includes a drive-train assembly pivotally mounted to a main structural frame. A suspension system biases the drive-train assembly and its connected anti-tip wheel to a predetermined resting position. The drive-train assembly bi-directionally rotates about a pivot in response to torque applied to or acceleration forces on the vehicle. A linkage arrangement is provided and is characterized by a suspension arm pivotally mounting to the main structural frame about a pivot at one end thereof and an anti-tip wheel at the other end. The linkage may further include at least one link operable to transfer the bi-directional displacement of the drive-train assembly to the suspension arm. The link may include a bell crank member and/or may be resiliently compressible.

Abstract: A medical chair includes a base and a pair of arm rests supported relative to the base for movement between a raised position and a lowered position relative to the base. The raised position of at least one of the arm rests is upward and forward of its lowered position to provide support to a patient when exiting the chair. For example, the arm rest may be mounted relative to the base to move between the raised position and the lowered position along a linear path.

Abstract: A rise assisting structure includes a main body, a seat unit, two operation bars, and two support units. The seat unit is pivotally connected, at one side thereof, to the main body. The operation bars are pivotally mounted to the main body. The operation bars are provided at one end thereof with a step board arranged therebetween. The support units are each of an elastic extendable/retractable arrangement. When the step board is treaded down, the operation bars provide a torque in a way similar to a seesaw and the support units provide an elastically-support upward-pushing effect to raise up the seat unit so as to allow a user, with or without the assistance of an attendant person, to rise and stand up easily.

Abstract: A patient support structure includes a pair of independently height-adjustable supports, each connected to a patient support. The supports may be independently raised, lowered, rolled or tilted about a longitudinal axis, laterally shifted and angled upwardly or downwardly. Position sensors are provided to sense all of the foregoing movements. The sensors communicate data to a computer for coordinated adjustment and maintenance of the inboard ends of the patient supports in an approximated position during such movements. A longitudinal translator provides for compensation in the length of the structure when the supports are angled upwardly or downwardly. A patient trunk translator provides coordinated translational movement of the patient's upper body along the respective patient support in a caudad or cephalad direction as the patient supports are angled upwardly or downwardly for maintaining proper spinal biomechanics and avoiding undue spinal traction or compression.

Abstract: A device for the passive movement of the fingers for the therapeutic treatment of a patient includes a plurality of supporting elements, each one adapted to receive a finger of a patient, and a movement unit having a plurality of actuating elements each one operatively connected to one respective of the supporting elements so as to move it with movements uncoordinated from the movements of the other supporting elements which are moved with other actuating elements; a plurality of motion transmission members each one interposed between one of the actuating elements and one respective of the supporting elements and all of them designed to move the supporting elements with three degrees of freedom.

Abstract: An exercise apparatus adapted to hang from an overhead structure used for providing walking and ambulation assistance to users in aid of exercise and physical rehabilitation. The device has a pulley assembly adapted for anchoring directly to an overhead structure or indirectly by a track secured thereto, and includes a hoist line permitting manual force to be used to raise and lower a sling assembly that is secured in the underarms of the user for lifting.

Abstract: A body therapy apparatus is provided which enables the user to easily and comfortable engage the various muscles of the leg, providing the leg muscles with a therapeutic message and assisting with the removal of cellulite from affected areas of the leg. The apparatus is basically comprised of a frame structure means, a user engagement means, a coupling means, and an optional resistance means. The main support members are adjustably coupled together by the coupling means such that they may alternatively move away and towards one another, as the various leg muscles of the user are being engaged by the user engagement means, which mount along the inside of the support members. The optional resistance means may be used to provide motion resistance.

Abstract: An apparatus and method are disclosed for orally administering to a recipient a medication, in a liquid form, and a flavor for rendering the medication more palatable to the recipient. A manually-operated liquid dispenser dispenses a measured dose of the medication at an administering head comprised of an edible flavored material placed within a recipient's mouth. A handle is coupled with the dispenser, by inserting either one into a receptacle of the other, and the dispenser is operated manually to dispense the medication through a dispensing outlet located relative to the administering head to assure administering substantially all of the measured dose of medication to the recipient's mouth while flavor is derived from the edible flavored material for being present with the measured dose of medication.

Abstract: The present invention relates to a container (1) for preparing of a nutritional composition from a powdered or concentrated liquid nutritional formula base, the container (1) comprising: —liquid inlet means (6) designed to be supplied with liquid from liquid dispensing means (20), —an adaptor (4) being provided with engagement means (2) for connecting the container (1) to matching engagement means (20a) of the liquid dispensing means (20), and —a flexible wall portion (31), connected to the liquid inlet means (6) and at least partially defining a compartment (3) for containing a predefined amount of powdered or concentrated liquid nutritional formula base (5) for the preparation of the nutritional composition (5a) upon hydration with the supplied liquid, wherein the flexible wall portion (31) is expandable in a manner that the volume of the compartment increases from a retracted position to an expanded position allowing a sufficient volume of liquid to be supplied into the compartment (3) through said liquid

Abstract: A multi lumen gastrointestinal catheter is disclosed. The multi-lumen gastrointestinal catheter has a flexible partition separating a feeding and an aspiration channel. A third smaller inflation channel is positioned within the outside exterior wall at the site of the flexible partition to avoid kinking at the inflation channel site, without need to re-enforce the weakened wall.

Abstract: A feeding kit forming a storage and preparation assembly for infant feeding implements that includes a receptacle to receive a teether and a plurality of wells to form food/drink inserts for the teether. The teether includes a lid that is removably coupled to a feeding portion, such that the inserts may be inserted into the feeding portion, a portion which includes a feeding member with a plurality of apertures.

Abstract: Disclosed herein are dental temporary filling material and cement formulations comprising a hydrophobic matrix of a hydrophobic material in which an inorganic hardening material and fine, hydrophilic, water-insoluble solid particles are dispersed. The hydrophilic particles serve to conduct water into the hydrophobic matrix to increase the depth and degree of cure in the oral environment as compared to a similar or substantially identical formulation lacking said hydrophilic component.

Abstract: Provided is a dentifrice composition which has excellent dental caries preventive effect by improving the uptake of fluoride ions into tooth enamel or dentin and improving acid resistance. A dentifrice composition comprising the following components (A), (B), (C) and (D): (A) from 0.002 to 5% by mass of a fluoride ion supplying compound in terms of fluorine, (B) from 25 to 65% by mass of a sugar alcohol, which is dissolved in an amount of 5 to 30 g in 100 g of an aqueous solution at 20° C., (C) from 10 to 25% by mass of water, and (D) from 0.1 to 1.2% by mass of a binder, wherein the mass ratio of the component (B) to the component (C), the mass ratio (B/C), is more than 1 and 6 or less.

Abstract: The invention provides an oral care composition suitable for delivering a temporary whitening effect to the surface of teeth, the composition comprising: a continuous phase comprising water or polyhydric alcohol or a mixture thereof; a tooth surface whitening agent which is dispersed in the continuous phase, and a deposition aid for the tooth surface whitening agent; characterized in that the tooth surface whitening agent is a pearlescent pigment in an amount of at least 0.1% by weight based on the total weight of the composition, the pearlescent pigment being formed by coating one or more metal oxide layers onto particles of an inorganic substrate.

Abstract: A detergent composition excellent in an antimicrobial activity. Thus, a detergent composition of the present invention is characterized by including: an imidazolinium betaine-based amphoteric surfactant; and 0.5 to 10% by mass of PEG-1 lauryl glycol represented by the following formula (I): wherein, m and n each represent the number of moles of added ethylene oxide and the average of m+n is 1. Also, the detergent composition preferably includes an ingredient having a microstatic effect or microcidal effect selected from divalent glycols, hinokitiol, trichlorocarbanilide, and benzalkonium chloride.

Abstract: Disclosed are methods of mitigating the effects of exposure to oxidizing agents, chlorinating and/or brominating agents on biological and/or synthetic fibers, by treating the body and/or clothing fibers with an effective amount of a composition comprising compounds of formula A. Also disclosed are compositions comprising compounds of formula A, for use in treating biological and/or synthetic fibers to mitigate the effects of exposure to chlorinating and/or brominating agents.

Abstract: Disclosed herein is a fragrant formulation comprising a fragrant composition, and an alkyl ketal ester. Disclosed herein too are methods for manufacturing the fragrant formulation.

Abstract: Provided is a method for preventing or treating a periodontal disease; or a method for improving oral hygiene, including administering a pharmaceutical composition containing tauroursodeoxycholic acid as an active ingredient.

Abstract: The present invention relates to a material comprising dendritic molecules each constituted of fragments that are at least bifunctional and of fragments that are at least trifunctional joined together by ester or thioester bridges, alone or in combination with amide or urea bridges, said bridges being formed from two functions carried by different fragments, said molecules containing, on the fragments located at the ends of the dendritic branches, associative end groups capable of forming associations with one another by hydrogen bonds and joined covalently to the functions that are not involved in said bridges. It also relates to the method of production thereof, as well as to its uses and to compositions, notably cosmetic, containing this material.

Abstract: The present invention relates to an organopolysiloxane elastomer having a group having a siloxane dendron structure bonded to a silicon atom, and having a crosslinked structure that includes a carbon-silicon bond in the crosslinking portion, and relates to a glycerin derivative-modified organopolysiloxane elastomer having a siloxane dendron structure bonded to a silicon atom and a hydrophilic group bonded to a different silicon atom from the silicon atom, and having a crosslinked structure that includes a carbon-silicon bond in the crosslinking portion.

Abstract: A body cosmetic for application to wetted skin after showering, and the like, which provide high moisturizing effects, all over body spreadability, and easy application with a non-greasy and non-sticky feeling. An oil-in-water body cosmetic for application to wetted skin, which contains the following components (A) to (D): (A) from about 0.1% to about 1% of block copolymer; (B) from about 3% to about 10% branched fatty acid ester; (C) from about 3% to about 20% hydrocarbon oil; and (D) from about 5% to about 50% glycerin.

Abstract: A protective coating material applied to whitened or bleached teeth. The protective coating material comprises microcrystalline wax, mineral oil, vitamin E, and amorphous calcium phosphate or ACP. The protective coating material covers the whitened or bleached tooth surface protecting it from staining thereby prolonging the whiteness of the teeth. The whitened or bleached damaged tooth enamel may also be strengthened or repaired.

Abstract: The present invention relates to a synthetic solid bar cleanser formulated to clean human skin. More particularly, the present invention relates to synthetic solid cleanser formulations which have pH of about 5.5, the same as human skin, and yet which perform similarly, or superior, to traditional soap.

Abstract: Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.

Abstract: The present disclosure provides an immediate release, abuse deterrent pharmaceutical solid dosage form comprising at least one functional score. In particular, the immediate release, abuse deterrent solid dosage form comprises at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.

Abstract: The invention relates to compositions suitable for the delivery and/or stabilization of biologically active substances. The compositions comprise a sublimable matrix material and the biologically active agent to be delivered. The compositions can be used as drug delivery systems to treat a wide variety of diseases or as systems for the protection and stabilization of such substances. Also disclosed are methods for preparing compositions of the present invention.

Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.

Abstract: An edible, gel composition of a PEG and a gel forming agent wherein the composition is prepared by mixing together the PEG with gel forming agent to form the edible gel composition, and the edible gel composition has laxative properties.

Abstract: The administration of levoleucovorin is useful as an antidote to drugs which act as folic acid antagonists and in combination chemotherapy with 5-FU. The most often used calcium salt of levoleucovorin has a limited solubility in water and forms almost insoluble degradation products. Therefore aqueous solutions are unstable and precipitates are resulting. Precipitates in injectable products present an unacceptable safety risk to patients. Stable high strength pharmaceutical aqueous compositions containing calcium salts, magnesium or zinc salts of levoleucovorin and one or more of the compounds sodium gluconate, potassium gluconate, glycerophosphate disodium salt or glycerophosphate dipotassium salt are disclosed.

Abstract: Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.

Abstract: Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided. Methods of forming microparticles containing one or more cells encapsulated by a substrate are also provided, as are methods of forming an array of said microparticles.

Abstract: Drug-eluting devices and methods for the treatment of tumors of the pancreas, biliary system, gallbladder, liver, small bowel, or colon, are provided. Methods include deploying a drug-eluting device having a film which includes a mixture of a degradable polymer and a chemotherapeutic drug, wherein the film has a thickness from about 2 ?m to about 1000 ?m, into a tissue site and releasing a therapeutically effective amount of the chemotherapeutic drug from the film to treat the tumor, wherein the release of the therapeutically effective amount of the drug from the film is controlled by in vivo degradation of the polymer at the tissue site.

Abstract: The present invention provides single sheet and compound para-xylene films for therapeutic uses. For example, the present invention provides single sheet para-xylene films useful as tissue separators and/or adhesion barriers in a subject, where the top and/or bottom surfaces of such films have a water contact angle between 75 and 95 degrees (e.g., to prevent adhesion formation). The present invention also provides compound films composed of at least two para-xylene polymer films with a therapeutic molecule layer in between. Such compound films, when used in vivo (e.g., as a tissue separator and to treat inflammation or atrial fibrillation) allow either therapeutic molecule elution through one of the para-xylene layers, or therapeutic molecule release when the compound film is pierced, such as when it is sutured in place.

Abstract: The disclosed conformable coating provides a highly durable and resilient film useful for protecting and repairing surfaces such as skin and mucous membranes. The coating comprises 0.1% to 65% wt. of a polymerized cyanoacrylate monomer and at least 35% wt. of an elastomer phase. The conformable coating composition comprises a polymerizable cyanoacrylate monomer, an elastomer, and a volatile liquid. The cyanoacrylate monomer is 0.1 to 65% wt. of the nonvolatile portion, the elastomer in an elastomer phase is at least 35% wt. of the nonvolatile portion, and the volatile liquid is at least 40% wt. of the total composition.

Abstract: The present invention relates to Substituted Biaryl Derivatives, compositions comprising a Substituted Biaryl Derivative, and methods of using the Substituted Biaryl Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.

Abstract: A refreshment towel with applied solution is an apparatus consisting of a carrying agent, most likely a high quality cotton towel or towelette, that has been saturated with an aqueous solution comprised of various ingredients. The resulting saturated towel can be rubbed on a user's skin such that the aqueous solution that has been absorbed by the towel is transferred. The aqueous solution is compounded specifically to provide cooling, insect repellant, sun protection, freshness, cleansing and other uses. More specifically, the aqueous solution is specially formulated so that desired sensory results take place when the towel comes in contact with the skin.