Abstract: A non-contact blood-pressure measuring device includes: an image acquiring section that acquires a skin image obtained by capturing skin of a user; a pulse-wave timing calculating section that calculates, as a pulse-wave timing, time information indicative of a time at which time-varying luminance in the skin image reaches a peak; a millimeter-wave acquiring section that acquires a signal of a radio wave reflected by the user; a heartbeat timing calculating section that calculates, as a heartbeat timing, time information indicative of a time at which a time-varying distance to the user obtained on the basis of the signal of the radio wave acquired by the millimeter-wave acquiring section reaches a peak; and a blood-pressure determining section that determines blood pressure of the user on the basis of a time difference between the pulse-wave timing and the heartbeat timing.

Abstract: The present invention provides a heartbeat and pulse measuring system comprising a detecting unit, a processing unit and an outputting unit. The detecting unit includes a first light-emitting element, a second light-emitting element and a detecting module. The first light-emitting element emits a first frequency beam to a user's body to generate a first scatter light signal. The second light-emitting element emits a second frequency beam to the body to generate a second scatter light signal. The detecting module receives first scattered light signal and the second scattered light signal to covert into a first current signal and a second current signal respectively. The processing unit analyzes and calculates the intensity difference associated with time between the first current signal and the second current signal to produce an analysis information, then the analysis information is outputted by the outputting unit.

Abstract: Provided is a multi-point probe which is formed of a tubular laminate which is configured by winding an electronic contact sheet including a sheet-shaped insulating base material, a plurality of electronic contacts which are arranged to be separated from each other in a column shape on the sheet-shaped insulating base material, and a plurality of wirings which are connected to each of the electronic contacts on the sheet-shaped insulating base material from a first end towards a second end and laminating the electronic contact sheet to have multiple layers, in which the electronic contacts are not covered with the sheet-shaped insulating base material and are exposed, and the wiringsther than a wiring on the uppermost layer are laminated so that at least some parts thereof are covered with the sheet-shaped insulating base material.

Abstract: Provided is a method for denoising of electroencephalography. The method for denoising of electroencephalography (EEG) includes: generating a two-dimensional data matrix (X) from a one-dimensional EEG signal (x), based on segmentation; generating an eigenvector matrix (E) from the two-dimensional data matrix (X), using principal component analysis (PCA); and removing noise in the one-dimensional EEG signal (x), based on a center-frequency and kurtosis for each of a plurality of eigenvectors. The device for denoising of electroencephalography is also provided.

Abstract: An efficient system for diagnosing arrhythmias and directing catheter therapies may allow for measuring, classifying, analyzing, and mapping spatial electrophysiological (EP) patterns within a body. The efficient system may further guide arrhythmia therapy and update maps as treatment is delivered. The efficient system may use a medical device having a high density of sensors with a known spatial configuration for collecting EP data and positioning data. Further, the efficient system may also use an electronic control system (ECU) for computing and providing the user with a variety of metrics, derivative metrics, high definition (HD) maps, HD composite maps, and general visual aids for association with a geometrical anatomical model shown on a display device.

Abstract: A position detection device detects a position of a capsule medical device having therein a magnetic field generator for generating a magnetic field. The position detection device includes: magnetic field detection units each configured to detect the magnetic field generated by the magnetic field generator and to output a detection signal; and a position calculation unit that calculates the position of the capsule medical device based on the detection signal output from each magnetic field detection unit. The magnetic field detection units are arranged on a single plane, the plane having: a first region formed by projecting a closed detection target space for detecting the capsule medical device on the plane; and a second region that is a closed region on the plane and includes the first region and is larger than the first region by a predetermined ratio. The magnetic field detection units are arranged in the second region.

Abstract: A medical instrument includes an insertion portion, first transmitting coils, second transmitting coils, a signal control unit, a position detection unit, a memory, and a position estimating unit. The signal control unit controls the first transmitting coils to transmit magnetic fields during a first predetermined period and controls the second transmitting coils to transmit magnetic fields during a second predetermined period. The position detection unit detects positions of the first transmitting coils during the first predetermined period and detects positions of the second transmitting coils during the second predetermined period. The memory stores the positions of the first transmitting coils. The position estimating unit estimates a shape of the insertion portion based on the positions of the second transmitting coils and the positions of the first transmitting coils stored in the memory.

Abstract: The present technology relates generally to devices for electronically registering a surgical patient to his or her own pre-surgical image scan and associated systems and methods. In some embodiments, a surgical navigation registration device configured in accordance with the technology comprises a patient-specific inner surface having at least one contour element that matches a contour of an outer surface of at least a portion of the patient's anatomy, and at least three registration pathways incorporated in the device and configured to mate with the tip of a surgical navigation system tool, such as a pointer. The registration pathways may be configured to enable the tip of the surgical navigation system tool to directly contact the patient's anatomy or, alternatively, to prevent the tip of the surgical navigation system tool from directly contacting the patient's anatomy. The registration pathways may comprise channels that extend through the patient-specific inner surface.

Abstract: Disclosed herein is one embodiment of a biometric device that includes a housing, a sensor, and a controller. The housing has a main chamber and a breath chamber. The breath chamber has an inlet and an outlet. The sensor is coupled to the main chamber and is at least partially in fluid contact with the breath chamber. The sensor is configured to detect the concentration of at least one gas of a user's breath in the breath chamber. The controller is coupled to the housing and is disposed within the main chamber. The controller is configured to receive the concentration of the at least one gas in the user's breath in the breath chamber and determine a health score.

Abstract: An integrated movement assessment system (IMAS) that monitors a subject's movement by utilizing electromyography (EMG), range-of-motion (ROM) and functional capacity assessment (FCA). The EMG, ROM and FCA is used in combination with proprietary software that acquires data from wireless sensors which are attached to the subject and are capable of transmitting data wirelessly. In addition to assessment, the IMA can perform baseline and post-loss comparisons that are specific to a subject's occupation. When necessary or desired, the IMAS can also provide site-specific therapy.

Abstract: The present invention relates to a light-weight, small and portable ambulatory sensor for measuring and monitoring a person's physical activity. Based on these measurements and computations, the invented system quantifies the subject's physical activity, quantifies the subject's gait, determines his or her risk of falling, and automatically detects falls. The invention combines the features of portability, high autonomy, and real-time computational capacity. High autonomy is achieved by using only accelerometers, which have low power consumption rates as compared with gyroscope-based systems. Accelerometer measurements, however, contain significant amounts of noise, which must be removed before further analysis. The invention therefore uses novel time-frequency filters to denoise the measurements, and in conjunction with biomechanical models of human movement, perform the requisite computations, which may also be done in real time.

Abstract: The present invention relates to systems and methods for the measurement of analytes such as glucose. Raman and reflectance spectroscopy are used to measure a volume, of material such as a blood sample or tissue within a subject and determine a concentration of a blood analyte based thereon. The present invention further relates to a calibration method, constrained regularization (CR), and demonstrates its use for analyzing spectra including, for example, the measurement glucose concentrations using transcutaneous Raman spectroscopy.

Abstract: Provided are a biosensor and a wearable device for detecting bioinformation including a hybrid electronic sheet. The biosensor has high electrochemical activity, allows DET-based detection of an analyte in a sample, and has an electrode harmless to the human body to detect an analyte with high sensitivity and selectivity, thereby being usefully applied to a wearable device of detecting bioinformation.

Abstract: This patent is a combined non-invasive method of monitoring glucose level. Monitoring the concentration of glucose level in human blood and tissue was developed by a combined non-invasive technique. This combined method includes skin temperature and pulse wave measurement. All these measurements are used to calculate the blood glucose level. This method also can be used to measure the diabetes related damage of micro arterial.

Abstract: The invention provides a pulse oximetry sensor for attachment to the lower half of the palm or the ulnar edge of the palm. The sensor may be portable, untethered and in some instances, disposable. The features of the sensor make it effective in stable, chronic or emergency medical settings.

Abstract: A tissue oximetry device utilizes at least three or at least four different wavelengths of light for collection of reflectance data where the different wavelengths are longer than 730 nanometers. The three or four wavelengths are utilized to generate a range of reflectance data suited for accurate determination of oxygenated hemoglobin and deoxygenated hemoglobin concentrations. The relatively long wavelengths decrease optical interference from certain dyes, particularly methylene blue and PVPI, which may be present on tissue being analyzed for viability and further enhance the generation of accurate reflectance data. The wavelengths are 760 nanometers, 810 nanometers, and 850 nanometers, or 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers.

Abstract: Embodiments of the present invention provide magnetic lancet devices and methods for driving a lancet. For example, a magnetic lancet device may include a driving mechanism having a plurality of magnets and a lancet coupled to the driving mechanism. A magnetic interaction between the plurality of magnets is configured to drive the lancet from an engaged position to a penetrating position.

Abstract: A specimen transfer device adapted to receive a blood sample is disclosed. The specimen transfer device includes a housing and an actuation member. A deformable material is disposed within the housing and is deformable from an initial position in which the material is adapted to hold the sample to a deformed position in which at least a portion of the sample is released from the material. A viscoelastic member is disposed within the housing between the material and the housing and between the material and the actuation member. The viscoelastic member is engaged with the actuation member and the material such that movement of the actuation member from a first position to a second position deforms the material from the initial position to the deformed position.

Abstract: A sampling device for a sampling container. A pair of elongate flexible arms extend from a side wall away from a bottom end. The arms being oppositely located across a base chamber. A lower member has a flange and an aperture. A collar extends from the flange and is adapted to retain an end of a spring. An elongate cover has a first end and a second end. The first end being adapted in use to connect to a base and the second end being adapted in use to connect to an upper member. The upper and lower members are adapted to move along the axis by the positioning of a sampling container in the sampling chamber and the application of a force towards a base, permits a needle or blood bag tube located within a connector to discharge liquid into a sampling container.

Abstract: The application discloses a lancet device (100) that includes a base (102) that supports a lancet (104) and a cover (106). The cover can move controllably from an un-depressed position to a depressed position when a predetermined force is applied. The cover can provide access to the lancet in the depressed position.

Abstract: There is provided an adapter for blood sample dispensing which enables change of the presence and absence of a medicine to be mixed in a blood sample or the type of the medicine thereof while suppressing contact of blood with the air, during preparation of an examination sample, and a dispensing kit and a needle kit provided therewith. Dispensing is performed using an adapter 1 for blood sample dispensing which is mounted on a distal portion of a syringe and has a piping structure, in which the adapter has a fitting portion 3 fitted to the distal portion at one end, a nozzle portion 2 at the other end, and a flange portion 4 on an outer circumference surface, and in which the adapter 1 has a medicine 5, to be mixed in the blood sample S, on the inside of the nozzle portion 2.

Abstract: Techniques for effectively and accurately measuring psychological influencing factors, such as the white coat effect and mental stress, that may affect or otherwise influence biometric measurements, such as blood pressure measurements, are described. Embodiments of a measurement validation system herein may utilize a method for determining an artery location on a living subject's skin and positioning a tonometry pressure sensor on the artery location for tonometric blood pressure measurement to obtain pressure pulse data for a subject. In operation according to embodiments, measurement logic of a measurement validation system may utilize the pressure pulse data to extract blood pressure data, heart rate data, blood pressure variability data, and heart rate variability data. The foregoing data may be utilized in identifying whether the blood pressure measurement properly and accurately reflects the situation of the subject.

Abstract: A brain dysfunction assessment device (100) comprises: a body movement indicator (10) which presents a body movement to be performed to a subject with a body movement presentation device (2); a body movement data acquisition unit (20) which acquires the subject's body movement data with a body movement detection sensor (3); a body movement accuracy calculation unit (30) which calculates a positional accuracy and a time sequence accuracy of the subject's body movement from the acquired body movement data; and a cognitive dysfunction assessment unit (40) which assesses the level of cognitive dysfunction of the subject by comparing a value which indicates the accuracy of the subject's body movement that is obtained from the calculated positional accuracy and time sequence accuracy with statistical data which indicates the accuracy of body movement of healthy individuals.

Abstract: Disclosed herein is a computer-aided diagnosis system and a computer-aided diagnosis method. This method includes the step of performing a principal component analysis to acquire an effect of light and shade portions from a color image of skin to serves as a first principal component. This method performs the principal component analysis further to acquire a second principal component and a third principal component, and the second and third principal components contain color variability. The third principal component is correlated with a skin cancer and serves as a main indicator of variegated colors for malignancy diagnosis.

Abstract: The present invention relates to systems and methods for early detection, assessment, monitoring and prevention of pathophysiological conditions originating and/or emanating from skin or localized tissues, including but not limited to acute or chronic episodes of soft tissue pathology, wound, injury, dermatological or rheumatoid condition where bio-signal patterns, biomarkers or other identifiable elements or references would deviate from baseline. Specifically, the present invention relates to methods and systems specially designed and adapted for early detection of a latent pathogenic bio-signal anomaly using multiple aggregated sensors before the anomaly would otherwise be detectable.

Abstract: A method of measuring Bone Mineral Density (BMD) including providing a model of a plurality of constituents of at least a portion of a subject body, the model including at least one bone constituent, injecting electric current into the portion of the subject body using a current injection electrode, such that at least part of the current flows through the at least one bone constituent, measuring a value of electric potential at a surface of the subject body using a pickup electrode, using a value of the injected electric current as input to a model of the at least a portion of a subject body, and calculating a value of conductance of the bone constituent corresponding to a value of the injected electric current and the measured value of the electric potential. Related apparatus and methods are also described.

Abstract: A sleep state determination apparatus includes: a measurement unit which measures biological information; and a determination unit which calculates a first index in accordance with an activity of a first autonomic nerve and a second index in accordance with an activity of a second autonomic nerve, based on the biological information which is measured by the measurement unit, derives first variation information which indicates a variation of the first index and a second variation information which indicates a variation of the second index, and determines whether a sleep state indicated by the biological information is REM sleep or non-REM sleep, based on the first variation information and the second variation information.

Abstract: A system and method determines a user's compliance with a prescribed therapeutic pneumatic compression treatment by applying external pressure to a body limb using a pneumatic compression sleeve having a pneumatically fillable cell; measuring pneumatic pressure within the pneumatically fillable cell; generating a pressure signal corresponding to the measured pneumatic pressure; determining biological events associated with the user based upon the pressure signal; generating a positive detection signal for each determined biological event associated with the user; and determining a user's compliance with a prescribed therapeutic pneumatic compression treatment when a predetermined number of positive detection signals have been generated within a predetermined time interval.

Abstract: Systems and methods are provided for rapidly introducing treatment to patients suffering traumatic brain injuries. A wearable map of the brain electroencephalography (EEG) points is worn in a headscarf, helmet, or other headgear for providing real-time information on a wearer's brain condition. The overall system includes an application (app) or program software that may run on a tablet, portable communication device, or computing device that processes the data from the EEG sensors and interprets the data in real time. If there is an accident or other stress forces experienced by the wearer that mimics a concussion, the system initiates the real-time ejection of a cooling agent within the headgear to provide a reduction in the victim's brain temperature with the helmet cooling system. A drug intervention system and injury detection app for expedited treatment of a potential brain injury during the critical early phases of the injury is also provided.

Abstract: A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present.

Abstract: A method, including subjecting the recipient to a plurality of groups of tasks, respective groups of tasks corresponding to respective sets of parameters by which the device will be fitted, obtaining data indicative of respective listening effort associated with the respective groups of tasks based on performance of the recipient of the respective groups of tasks, at least partially fitting the hearing prosthesis to the recipient based on the obtained data.

Abstract: Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be included with the access needle to provide image data and/or cardiac waveform information of the subject.

Abstract: A garment and/or garment system with health-monitoring (e.g., cardiovascular monitoring) capability, substantially as shown in and/or described in connection with at least one of the figures, as set forth more completely in the claims.

Abstract: The invention provided herein relates to a wearable medical device and methods of use thereof for monitoring brain signals by electroencephalography technology in critically ill subjects suspected of having abnormal brain wave patterns including but not limited to electrographic seizures, spike and waves, periodic discharges and rhythmic delta activity.

Abstract: Methods and systems for detecting wall breach in inflatable prostheses rely on intrusion of a body fluid or inflation medium to electrically alter a signaling circuit. In one embodiment, an open portion of a circuit is closed to enable or modify a transmitted signal. In another embodiment, electrical current is generated to power an electrical transmission.

Abstract: A system for determining user kinematic characteristics includes a detachable motion sensor, a processing system, and a wireless transceiver. The motion sensor may be coupled with a user's footwear in order to generate one or more signals corresponding to the motion of the user's foot/feet. The processing system is in communication with the motion sensor and is programmed to use the one or more signals to determine one or more kinematic parameters. The present invention measures various parameters about each individual stride. The stride based kinematic characteristics may include, but are not limited to, pitch, roll, yaw, vertical position, horizontal position, horizontal velocity, vertical velocity, distance traveled, foot strike, foot strike classification, toe off, contact time, stride rate, stride length, rate of pronation, maximum pronation, rate of plantarflexion and dorsiflexion, swing velocity, and pitch-roll signature.

Abstract: A system for behavioral monitoring for equines, comprising at least one sensor to measure a signal related to the equine, a database to store at least one parameter of the equine as a function of time, and processing means. The sensor is in communication with the equine, and comprises a wireless transmitter which is in communication with the data-base. The processing means, in communication with the database, is adapted to (i) determine, from at least one signal from the at least one sensor, at least one parameter of the equine as a function of time; (ii) establish normal behavior of the equine based on the parameter; and (iii) identify at least one abnormal behavior of the equine by identifying at least one deviation from normal behavior.

Abstract: A method for communicating beat parameters to a user includes: providing an electrode module comprising a first and a second set of electrodes, associated with a first and a second sensor channel, respectively; receiving a first and a second dataset based on a first and a second set of bioelectrical signals detected from the first and the second sensor channel, respectively; receiving a supplemental dataset based on supplemental bioelectrical signals detected from a supplemental sensor module; generating a noise-mitigated power spectrum upon: generating a combined dataset based upon combining the first and second datasets, calculating 1) a heart power spectrum based on the combined data set, and 2) a supplemental power spectrum based on the supplemental dataset, and generating a noise-mitigated power spectrum based on processing the heart power spectrum with the supplemental power spectrum; and rendering information derived from a beat parameter analysis to the user.

Abstract: A method for measuring a physiological parameter, such as a biological rhythm, on the basis of at least two sensors, and to an associated measurement device. The method includes the following steps of: measuring the physiological parameter for each sensor, allowing the generation of a series of measurements of at least two values; evaluating the level of consistency of each value from the measurement series; selecting a value from the set of values in the series as a function of the corresponding level of consistency and a so-called reference value, in order to determine a new reference value; and storing the new reference value.

Abstract: According to an aspect, there is provided a method of operating a non-invasive blood pressure, NIBP, monitor to measure the blood pressure of a subject, the NIBP monitor comprising a cuff, a pressure sensor for measuring the pressure in the cuff and for outputting a pressure signal representing the pressure in the cuff and a physiological parameter sensor, the method comprising obtaining a first measurement of a physiological parameter for the subject during inflation of the cuff, the first measurement being obtained from the pressure signal; obtaining a second measurement of the physiological parameter for the subject during inflation of the cuff, the second measurement being obtained from the physiological parameter sensor; comparing the first measurement and the second measurement; and estimating the reliability of a blood pressure measurement obtained by the NIBP monitor during inflation of the cuff based on the result of the step of comparing.

Abstract: Methods, systems, and computer readable media for predicting early onset glaucoma via structural parameters obtained via time and spectral-domain optical coherence tomography (SD-OCT) are disclosed. SD-OCT technology measures the thicknesses of the layers of the retina that contain the cells that die in glaucoma before there is any functional loss. A multivariable predictive model may be used for the diagnosis of early glaucoma using a combination of optic nerve head (ONH), peripapillary retinal nerve fiber layer (RNFL), and macular ganglion cell-inner plexiform layer (GCIPL) parameters measured via SD-OCT. The model generates a glaucoma probability score for individual patient, which is valuable information in assisting clinicians in glaucoma diagnosis and treatment.

Abstract: This disclosure provides systems, methods and apparatus for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor. The system may include a display device with at least one input device. In response to movement of or along the input device, the display device may change a glucose data output parameter and update an output of the display device using the changed output parameter.

Abstract: A system and method comprise sampling a rate of airflow in a patients lungs during inspiration and/or expiration of the patient and outputting a corresponding airflow signal. Respiratory muscles signals of the patient are simultaneously sampled with the sampling of the airflow and outputted as a corresponding activity signal. The airflow signal and the activity signal are simultaneously displayed wherein a comparison of at least the airflow signal and the activity signal indicates physical properties of a respiratory system of the patient.

Abstract: Provided according to embodiments of the present invention are multiparameter monitors that include a primary screen that displays signals or parameters provided by at least one parameter module; and a parameter module that includes a detachable processing device.

Abstract: Medical overlay mirror methods and related systems.

Abstract: A periodontal disease testing apparatus of the present invention includes: an X-ray CT scanner photographing a portion including a tooth, a gingiva, and alveolar bone within an oral cavity to generate volume data of the portion; region setting means setting a related region of a subject tooth based on the volume data; defining means defining a principal axis of the subject tooth; correcting means correcting the related region so as to align the principal axis of the subject tooth with a normal direction of a cross-section of an X-ray CT image; multi-planar reconstruction image generating means generating a multi-planar reconstruction image of the corrected related region; means for generating developed image and the like transforming a coordinate of the related region to generate a developed image and a rotated image; and navigating means indicating correspondences of a spatial coordinate among the multi-planar reconstruction image, the developed image, and the rotated image.

Abstract: A method of manufacturing an X-ray detector includes: applying a mask having an opening on a substrate on which a plurality of charge detection units are positioned; filling the opening with a paste including a photoelectric conversion material that absorbs X-rays to generate charges; and forming a photoconductive layer from the paste by separating the mask from the substrate. A thickness of the paste within the opening is thicker in an area adjacent to at least one edge among edges of the opening than in areas around other edges.

Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The arm may be articuable. The X-ray tube may include a target element configured to generate an X-ray beam and a collimator configured to shape the X-ray beam. The target element may be disposed at a set distance from the collimator.

Abstract: A method for generating a 3-dimensional reconstruction model of an object of interest that lies within a volume, the method executed at least in part by a computer, acquires a first set of projection images of the volume at a first exposure and a first field of view and a second set of projection images of the object of interest within the volume at a second exposure that is higher than the first exposure and a second field of view that is narrower than the first field of view. An object of interest is reconstructed from the second set of projection images according to information related to portions of the volume that lie outside the object of interest. The reconstructed object of interest is displayed.

Abstract: According to an embodiment, an X-ray computed tomography apparatus includes reconstruction circuitry and control circuitry. The reconstruction circuitry is configured to, at the time of the monitoring scan, based on an output of an X-ray detector for detecting X-rays having passed through the object, reconstruct a first image concerning the object at the time of administration of the contrast medium and a second image concerning the object after a predetermined period elapses since administration of the contrast medium. The control circuitry is configured to shift from the monitoring scan to the actual scan based on a change amount of a CT value obtained when the entire reconstructed first image is compared with the entire reconstructed second image.