Abstract: A Jones matrix OCT offers improved image stability, image quality, and depth range of image, wherein light from a wavelength-scanning light source is split into two optical paths, and a reference arm is provided along one optical path, while a probe arm that irradiates and reflects light onto the measuring target to generate object light is provided along the other optical path. The probe arm has a polarization delay unit that linearly polarizes the light and then splits it into S-wave component and P-wave component, where the S-wave component and P-wave component are superimposed through optical paths of different optical path lengths, respectively, after which optical detectors are used to detect different spectral interference beams in the depth direction of the measuring target corresponding to the vertically polarized component and horizontally polarized component, which respectively correspond to the S-wave component and P-wave component, to obtain four spectral interference signals.

Abstract: A biological state estimating apparatus includes a pair of electrocardiographic electrodes, a photoplethysmographic sensor, and a controller that includes a peak detecting section, a pulse transmission time measuring section, a correlation information storing section, and a biological state estimating section. The electrocardiographic electrodes detect an electrocardiogram signal and the photoplethysmographic sensor, which has light-emitting and light-receiving elements, detects a photoplethysmogram signal. The controller detects peaks of the electrocardiogram and photoplethysmogram signals and determines a pulse transmission time from the time difference between the respective peaks of the photoplethysmogram and the electrocardiogram signal. Memory stores information determined in advance based on the relationship between pulse transmission time and biological state.

Abstract: A method and system for determining fractional flow reserve (FFR) for a coronary artery stenosis of a patient is disclosed. In one embodiment, medical image data of the patient including the stenosis is received, a set of features for the stenosis is extracted from the medical image data of the patient, and an FFR value for the stenosis is determined based on the extracted set of features using a trained machine-learning based mapping. In another embodiment, a medical image of the patient including the stenosis of interest is received, image patches corresponding to the stenosis of interest and a coronary tree of the patient are detected, an FFR value for the stenosis of interest is determined using a trained deep neural network regressor applied directly to the detected image patches.

Abstract: A PPG system for determining a stroke volume of a patient includes a PPG sensor configured to be secured to an anatomical portion of the patient. The PPG sensor is configured to sense a physiological characteristic of the patient. The PPG system may include a monitor operatively connected to the PPG sensor. The monitor receives a PPG signal from the PPG sensor. The monitor includes a pulse trending module determining a slope transit time of an upslope of a primary peak of the PPG signal. The pulse trending module determines a stroke volume of the patient as a function of the slope transit time.

Abstract: A device adapted for determining cardiac viability, wherein said device includes: a cannula having a hollow body and at least a distal end adapted for insertion into a heart and operator end for adapted for an operator to position the catheter in the ventricular apex and adapted for connection to a plumbing system; an inflatable balloon positioned near to the distal end in fluid communication with the hollow body to allow for selected inflation of the balloon, a controller adapted to calculate the viability of the heart from pressure data detected within cannula or balloon which is inflated to various degrees with an incompressible fluid.

Abstract: A heart monitoring method is disclosed including an electroacoustic transducer such as an earphone coupled to a controller. The method proceeds with positioning a transducer in a person's ear in acoustic communication with the tympanum. Signals from the transducer are processed to determine the presence of pulsatile blood flow. The heart monitor may be incorporated into a portable media playback device alternating between playback and monitoring mode or performing both simultaneously using one earphone for each function. The heart monitor may be incorporated into a defibrillator to sense the presence of blood flow for use in a shock delivery decision.

Abstract: Provided is an apparatus and method for detecting biometric information. The apparatus may include a biometric signal measurer comprising a light-receiving element and a plurality of light-emitting elements; and a processor including a tracking unit configured to sequentially drive the plurality of light-emitting elements, receive a signal detected by the light-receiving element, and determine a tracking line that connects at least two positions of a radial artery of the object from the received signal; and an analyzing unit configured to detect a pulse wave signal at the at least two points on the tracking line and analyze biometric information from the detected pulse wave signal.

Abstract: Methods and devices for measuring blood flow velocity are provided. The device may include a wave source and at least two detectors positioned along a blood vessel. The wave source, which may include an ultrasound transducer or a mechanical source, is configured to induce a pressure wave in blood flowing in a blood vessel. In one example, the detectors are both positioned downstream of the wave source, with respect to the direction of blood flow. In another example, one detector is positioned upstream of the wave source, and a second detector is positioned downstream of the wave source. The difference in time it takes for the induced pressure wave to reach the first and the second detectors is indicative of the velocity of blood flow in the vessel.

Abstract: An apparatus for acquiring bio-information includes a light source configured to radiate a laser beam to a region of interest including a blood vessel; a sensor configured to sense, from the region of interest, a change of a laser speckle generated by the radiated laser beam; and a controller configured to obtain a bio-signal indicating a change in a blood flow in the blood vessel based on the sensed change of the laser speckle.

Abstract: What is disclosed is a system and method for determining arterial pulse transit time (PTT) for a subject. In one embodiment, time-series signals are received for each of a proximal and distal arterial site of a subject's body which represent blood volume changes in the microvascular tissue at each site. A proximal and distal analytic signal is obtained which has a first component being a waveform of the respective time-series signal and a second component being a transform of the respective waveform. A phase function is determined for the first and second components of each analytic signal. The phase function obtained for the proximal waveform is then subtracted from the phase function obtained for the distal waveform to get a phase difference. The phase difference is analyzed with the subject's heart rate to determine an arterial pulse wave transit time between the two proximal and distal sites.

Abstract: Aspects described herein include a computer-implemented method for detecting heart rate signals. The method includes a step of capturing a first image and a second image of a region of interest. The second image is aligned with the first image in a first spectrum that is insensitive to a characteristic to obtain a correction. Then, a correction based upon the above-mentioned alignment is applied to the second image in a second spectrum that is sensitive to the characteristic. Additional aspects described an image capturing device and a computer-implemented method for updating a user-interactive activity.

Abstract: A method of predicting cardiac disease includes the steps of: attaching a monitoring device to a patient; obtaining cardiac information from the patient using the monitoring device; transmitting the obtained cardiac information from the monitoring device to a data-computing device; analyzing the transmitted cardiac information using the data-computing device and a predictive model; building an indication report from the analyzed cardiac information; and outputting the indication report.

Abstract: A system and method for Multifractal-Detrended Fluctuation Analysis (MF-DFA) on digitized Human EEG signals is presented. A list of Hurst exponents, or Hurst exponent spectrum (“h” values) are generated, and multifractal singularity spectrum indices (“D(h)” values) produce a graph that approximates an inverted parabola. The output multifractal DFA spectrum is able to represent key features of the internal neuronal dynamics for the cortical neurons underlying the scalp-placed electrode which records the signals.

Abstract: According to one embodiment, an ECG waveform detecting apparatus includes an input circuit and processing circuitry. The input circuit receives an ECG signal. The processing circuitry performs first detection of a specific waveform included in the ECG signal, performs update processing of a detection parameter for detecting the specific waveform based on a part of the specific waveform or result of the first detection, performs second detection of the specific waveform from the ECG signal by using the detection parameter after the update processing, and generates a synchronization signal based on information on the second detection.

Abstract: A detachable biosignal complex sensor includes a clip type structure including: a circuit module configured to receive a biosignal of a subject and perform signal processing on the biosignal, a first plate, and a second plate having an end thereof which is rotatably connected to an end of the first plate so that the clip type structure is configured to be fastened to an item; and a sensor and electrodes provided on outer surfaces of the first plate and the second plate and configured to obtain the biosignal and transmit the obtained biosignal to the circuit module.

Abstract: A breast cancer imaging device with microwave surface impedance is a device which is used for imaging tumors in breast tissue using harmless electromagnetic waves in microwave band. It performs this function by using harmless electromagnetic waves without using X-ray. Thus, it can be performed in desired frequency, as many times as desired. Since compressing the breasts is no longer required, it is not a painful imaging process for the patient; moreover, it does not fail to detect the tumors that are close to the rib cage.

Abstract: An imaging and recordation system is provided. The system includes a high-power, focusing antenna for illuminating biological tissue. The system further includes a power source for powering the antenna. The system further includes a data acquisition module, for recording the dielectric properties of tissues illuminated by the high-power, focusing antenna. The system illuminates the tissues using ultrashort electrical pulses.

Abstract: An electrophysiology map, for example a map of arrhythmic substrate, can be generated by acquiring both geometry information and electrophysiology information pertaining to an anatomical region, and associating the acquired geometry and electrophysiology information as a plurality of electrophysiology data points. A user can select two (or more) electrophysiological characteristics for display, and can further elect to apply various filters to the selected electrophysiological characteristics. The user can also define various relationships (e.g., Boolean ANDs, ORs, and the like) between the selected and/or filtered characteristics. The user-selected filtering criteria can be applied to the electrophysiology data points to output various subsets thereof. These subsets can then be graphically rendered using various combinations of colorscale, monochrome scale, and iconography, for example as a three-dimensional cardiac electrophysiology model.

Abstract: Provided is a method of measuring body fat of a user, the method including: measuring a first impedance by using a 4-point measuring method; measuring a second impedance by using a 2-point measuring method; determining a bio impedance by using the first impedance and the second impedance; and determining a body fat percentage by using the bio impedance and body information of the user.

Abstract: A method for incorporating tomographically obtained image data from a patient into a system for surgical planning and/or intraoperative navigation involves tomographic image data or image data obtained by X-ray recordings from at least one defined body area of the patient by at least one first recording appliance, wherein a first reference body having at least one surface is arranged on the patient and is recorded by the first recording appliance at the same time. The recorded image data representing the first reference body are compared with known geometric data from the first reference body in order to obtain distortion information. The recorded image data are equalized by a computation unit based on the distortion information to obtain equalized image data which have further image data from the same body area superimposed to obtain superimposed image data that is presented on a display.

Abstract: A computer-implemented method is disclosed. The computer-implemented method comprises receiving, by a computer system, ingestible event marker (IEM) system information from a receiver worn by a subject, the IEM system information comprising information associated with ingestion of medication by the subject, wherein the receiver is configured to communicate with the computer system; receiving, by the computer system, contextual information associated with the subject; and calculating, by the computer system, a composite risk score based on the IEM system information and the contextual information associated with the subject.

Abstract: What is disclosed is a system and method for determining respiration rate from a video of a subject. In one embodiment, a video is received comprising plurality of time-sequential image frames of a region of a subject's body. Features of pixels are extracted from that region from each image frame and vectors formed from these features. Each image frame has an associated feature vector. A N×M video matrix of the vectors of length N is constructed such that a total number of columns M in the video matrix correspond to a time duration over which the subject's respiration rate is to be determined. The video matrix is processed to obtain a matrix of eigenvectors where principal axes of variations due to motion associated with respiration are contained in a first few eigenvectors. One eigenvector is selected from the first few eigenvectors. A respiration rate is obtained from the selected eigenvector.

Abstract: A pulmonary measurement system includes a pulmonary measurement device that includes a mouthpiece with an airflow path and a sensor positioned in the airflow path; and a controller communicably coupled to the sensor. The controller includes a processor and instructions stored in memory and is operable to execute the instructions with the processor to perform operations including identifying a measurement from the sensor; identifying a particular equation stored in the memory, the particular equation developed using data analytics and including an input parameter that is based on the identified measurement; and based on the identified measurement and the particular equation, determining a value of absolute lung volume.

Abstract: A measurement assembly of a personal health monitoring system for measuring the lung capacity of a person. In an embodiment, the measurement assembly includes a sensor assembly includes a sensor that is configured to sense the force of a fluid exhaled by the person onto the sensor and output a force measurement. In addition, the measurement assembly includes a control assembly coupled to the force sensing assembly, the control assembly configured to receive the force measurement from the sensor. Further, the measurement assembly includes a housing configured to support each of the sensor assembly and the control assembly. The sensor is disposed on an external surface of the housing.

Abstract: Breath analysis systems and methods test for infectious diseases in exhaled breath gas or condensate. An automatic breath sampling system can obtain reliable samples over a variety of clinical situations. In some variations, the system is modular system and can protect the equipment and clinician from contamination. In some variations, the system can be a point-of-care rapid-result instrument. In some variations, can be configured for off-line analysis in which case the collected sample is presented to a stand-alone analyzer for measurement.

Abstract: A platform for diagnosing movement disorder is disclosed. The platform comprises at least one inertia-sensing unit that comprises at least one accelerometer, wherein the inertia-sensing unit measures a user's movement; a power unit that provides power at least to the inertia-sensing unit; a processing unit that performs signal processing on the user's movement and quantifies the movement into a data; a diagnosing unit that analyzes the data to diagnose whether a movement disorder occurs by comparing the data to a database, where the database includes at least information about the user's movement characteristic; and a communication unit that establishes a communication with a computer, a mobile device or a computer server.

Abstract: A person support apparatus, such as a bed, cot, stretcher, or the like, includes an exit detection system that utilizes an occupant motion parameter to determine whether to issue an alert or not. The motion parameter may be based on the weight and motion of the occupant. Successive positions of the occupant are determined in order to calculate a velocity of the occupant. In some embodiments, the kinetic energy of the occupant is used to determine if an alert should be issued. Objects positioned on the person support apparatus may also be detected and tracked. Auto-zeroing of a built-in scale, as well as automatic recognition of the removal, movement, and/or addition of objects is also provided.

Abstract: Systems and methods are provided for determining an acceleration at a location of interest within one of a user's head and neck. At least one of linear acceleration data, angular acceleration data, angular velocity data, and orientation data is produced using at least one sensing device substantially rigidly attached to an ambient-accessible surface of the user's head. The location of interest is represented relative to a position of the at least one sensing device as a time-varying function. An acceleration at the location of interest is calculated as a function of the data produced at the sensing device and the time-varying function representing the location of interest. The calculated acceleration at the location of interest is provided to at least one of the user and an observer in a human-perceptible form.

Abstract: In accordance with one aspect of the present technique, a method includes receiving a plurality of images of an abdominal region from an image capture device. The method further includes identifying a bowel tissue and a peristaltic portion of the bowel tissue from the plurality of images. The method further includes determining a peristalsis property of the bowel tissue based on the peristaltic portion. The peristalsis property includes at least one of a percentage of the peristaltic portion within the bowel tissue and an amount of peristalsis in the peristaltic portion. The method also includes assessing a health the bowel tissue based on the peristalsis property of the peristaltic portion.

Abstract: The present invention provides a personal hygiene item. In simple terms, one of the main features of the present invention is to provide a low-cost personal hygiene item capable of providing a multi-component detection function. The personal hygiene item of the present invention mainly comprises a first material layer and a second material layer. The first material layer is made of hydrophobic material, and the second material layer is disposed thereon. Also, the second material layer comprises a discolored portion. In actual practice, a fluid under test contacts with the corresponding discolored portions via the hydrophobic layer of second material layer for a color changing reaction. Meanwhile, since the hydrophilic performance of the discolored portion is better than the hydrophilic performance of the hydrophilic layer, the back permeation of the fluid under test can herein be prevented.

Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with pushbutton activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing, all in one smooth motion. Some embodiments contemplate engagement of the transmitter with the housing after release of the applicator.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: A physiological signal processing apparatus and a method for the same. The physiological signal processing apparatus includes a first light-emitting element, a second light-emitting element, a light control module, an image sensing module and an analyzing module. The light control module is capable of controlling the first light-emitting element to emit a first light beam and the second light-emitting element to emit a second light beam on a light guide panel for a finger to touch. The image sensing module is capable of sensing the first light beam and the second light beam reflected by the light guide panel and acquiring an image signal of the finger. The analyzing module is capable of analyzing the image signal extracted by the first light beam to acquire a first physiological signal and analyzing the image signal extracted by the second light beam to acquire a second physiological signal.

Abstract: An optical source for guiding light to a target of a patient includes at least one light source configured to emit red light and infrared light. The at least one light source is embedded within a light-conducting sheet. A photodistributor is spaced from the at least one light source. The photodistributor includes a light-emitting surface and at least one light-receiving surface optically coupled to the light-conducting sheet. The photodistributor is configured to discharge at least a portion of the emitted red light and at least a portion of the emitted infrared light into a target.

Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

Abstract: A diagnosis supporting device includes a display, an imaging unit configured to capture a subject, an eye gaze detector configured to detect an eye gaze direction of the subject from a captured image captured by the imaging unit, a gaze point detector configured to detect a gaze point of the subject in a display region of the display, based on the eye gaze direction, an output controller configured to display, on the display, a diagnosis image that includes a person image and a geometric pattern image, and in which at least one of contrast, color density, and a degree of transmittance of the person image or the geometric pattern image is changed over time, and an evaluator configured to calculate an evaluation value of the subject, based on the gaze point detected by the gaze point detector when the diagnosis image is displayed.

Abstract: A system and a method for monitoring subject's eyes are disclosed. In one embodiment, spectral profiles of a frame substantially around a subject's eye are received from an image capturing device. Further, a state of the subject's eye in the frame is detected using the spectral profiles received from the image capturing device.

Abstract: A muscle condition change determination apparatus includes a circuit. The circuit configures: a change information acquisition unit; and a type determination unit. The change information acquisition unit acquires change information indicating changes in a plurality of muscle indicators. The type determination unit determines the type of change in a muscle condition according to the change information.

Abstract: The present invention relates to a cerebrovascular analysis system which enables early diagnosis of various incurable cerebrovascular diseases such as cerebral thrombosis by measuring an elastic coefficient, blood vessel compliance, blood flow resistance, and blood flow in each cerebrovascular branch. The measurement is achieved by biomechanically analyzing blood vessels in the brain using an electrocardiogram, phonocardiogram, electroencephalogram, pulse wave, and ultrasonic doppler signal as basic data in order to measure biomechanical properties and blood flow properties of blood vessels in the brain for the diagnosis of cerebrovascular diseases.

Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and infersaccatic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.

Abstract: The sphincter test catheter includes a catheter body, the proximal end of which forms a probe. Corresponding electric lines which are led to a recording unit run through the catheter body. The sphincter test catheter has at least one pressure sensor and a position sensor in combination with either a pH value sensor or an impedance sensor. The combination depends on which sphincter is to be monitored. The position sensor is combined with a pH value sensor in order to monitor the lower esophageal sphincter while the position sensor is combined with an impedance sensor when monitoring the urethral sphincter.

Abstract: An exercise feedback provision apparatus includes an acquirer configured to acquire exercise intensity information including either one or both of user biometric information and user movement information, and a controller configured to verify whether the exercise intensity information is in a predetermined range, and generate a control signal based on a result of the verifying. The apparatus further includes a feedback provider configured to output a tactile feedback based on a pattern corresponding to the control signal.

Abstract: A sleep surface insert system and method for positioning under, for example, an infant on a sleep surface. The sleep surface insert system includes an insert and a blower system. The insert includes a top liner and a bottom liner. The top liner and bottom liner define first and a second hollow spaces therebetween. Further, the top liner includes first and second pores such that the first pores extend through the top liner from the first hollow space and the second pores extend through the top liner from the second hollow space. In addition, the blower system is configured to provide air flow into the first and second hollow spaces defined in the insert such that the air flow is configured to flow into the insert and out of at least one of the first pores and the second pores.

Abstract: A computer-implemented method for providing summary information for lifesaving activities is disclosed. The method involves sensing one or more activities that are repeatedly and cyclically performed on a victim by a rescuer; identifying a cyclical timing interval over which performance is to be analyzed for a integer number of cycles of the one or more activities, and gathering data from the sensing of the one or more activities during the time interval; generating, from analysis of the one or more activities, summary data that condenses data sensed for the one or more activities into a summary of the one or more activities; and providing, for display to a user, a visual summary of the performance of the one or more activities over the identified time interval.

Abstract: Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The approaches as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

Abstract: Apparatuses and methods for corrective guidance of eating behavior of a patient equipped with a gastric restriction device. The apparatus provides continuous monitoring or one or more parameters related to food passing through the gastric restriction device. Each monitored parameter is processed to provide a visual indication of the current eating behavior. The visual indication is used as input to the patient or a caregiver to modify the eating behavior. In some embodiments, the apparatus includes an emergency relief mechanism that automatically relieves excess pressure developing in the gastric restriction device. In some embodiments, the apparatus is enabled to deliver an appetite suppressant to modify the eating behavior.

Abstract: A method and apparatus for extracting an anaerobic threshold are provided. The apparatus may acquire an electromyogram (EMG) signal, and may extract an anaerobic threshold based on a change in the EMG signal. The apparatus may extract a heart rate corresponding to the anaerobic threshold as an anaerobic threshold heart rate.

Abstract: The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: A monitoring device (24) includes a band (32), configured to fit around an appendage of a human subject (22), and one or more sensors (46, 58, 60, 62) fixed to the band and configured to sense physiological parameters of the human subject. In one embodiment, at least one visible light source (82) is fixed to the band. A controller (64) is fixed to the band and is coupled to receive signals from the sensors and to actuate the at least one visible light source in response to a state of the device. At least one flexible light guide (40) is embedded in an outer surface of the band while extending around at least a part of a circumference of the band when fit around the appendage, and is coupled to receive light from the visible light source and to emit the light from the outer surface in a bright stripe along a length of the light guide.

Abstract: An approach is provided for determining movement information for at least one user device based, at least in part, on air pressure sensor data. The approach involves determining reference air pressure data associated with a reference set of devices. The approach also involves processing and/or facilitating a processing of the reference air pressure data to cause, at least in part, a classification of the reference air pressure data into one or more candidate movement status categories. The approach further involves determining air pressure sensor data associated with at least one user device. The approach also involves determining at least one movement status category for the at least one user device from among the one or more candidate movement status categories based, at least in part, on the classification.