Patents Issued in May 19, 2016
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Publication number: 20160136052Abstract: PROBLEM To provide a co-infusion apparatus and a co-infusion method which can photograph an image suitable for inspecting whether or not a co-infusion process in the co-infusion apparatus is properly carried out. MEANS FOR SOLVING Provided is a co-infusion apparatus for suctioning a medicine from a medicine container 10 with an injector 11 based on preparation data and injecting the medicine from the injector 11 into the medicine container 10.Type: ApplicationFiled: September 8, 2014Publication date: May 19, 2016Applicant: Yuyama Mfg. Co., Ltd.Inventors: Naoki Koike, Akitomi Kohama, Masatoshi Warashina, Fumitaka Hino, Takuya Tsugui, Kazuki Kawauchi, Sho Oya
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Publication number: 20160136053Abstract: The device (1) has a housing (2), and a flexible bag arranged in the housing and intended to receive a liquid. A dispensing device, in particular an injection syringe (5), is also arranged in the housing, so that it is removable from the housing. A transfer channel (6) serves for direct or indirect transfer of the liquid from the bag into the dispensing device. At least one pressure plate (7) is also provided, which can be pressed against the bag in order to empty the bag. The pressure plate is preferably activated via a spring mechanism (16), which serves as energy accumulator. The device, according to the invention, makes it possible, with a few manoeuvres, to prepare an injection liquid and deliver it to the injection syringe, with the substances being brought together by a largely automated procedure.Type: ApplicationFiled: July 7, 2014Publication date: May 19, 2016Inventor: Ludwig Daniel WEIBEL
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Publication number: 20160136054Abstract: Methods and systems are described for monitoring medication use with a home automation system. An example medication monitoring system includes a medication storage device, a proximity device, and a dispenser module. The medication storage device is configured to hold a plurality of medications. The proximity device is configured to detect an activity of a user relative to the medication storage device. The dispense module is configured to detect a pattern of the activity based on data received from the proximity device, and generate a notice. The notice may be generated if the pattern is broken. The notice may include a summary report on usage of the medication storage device. The notice may include an alarm if the medication storage device is, for example, tampered with or moved.Type: ApplicationFiled: November 17, 2014Publication date: May 19, 2016Inventors: Brandon Bunker, Rongbin Lanny Lin, Harrison Taylor Jenkins
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Publication number: 20160136055Abstract: A data-enabled pharmaceutical container and methods for reminding at dose time, then tracking and communicating valid dose events and/or dose exception events are disclosed. Examples of dose exception events include, but are not limited to, missed doses, extra doses, early doses, and late doses. The data-enabled pharmaceutical container includes control electronics for processing and communicating information about valid dose events and/or dose exception events. For example, using a dose detection algorithm, a dose event is deemed valid based on (1) sensing the open state of the data-enabled pharmaceutical container (e.g., sensing that the closure is not present), (2) sensing a certain orientation or tilt of the data-enabled pharmaceutical container, and (3) sensing that the data-enabled pharmaceutical container is both opened and tilted simultaneously for a certain amount of time (e.g., a few seconds).Type: ApplicationFiled: January 19, 2016Publication date: May 19, 2016Applicant: DoseCue, LLCInventors: Mark Burrows, Neal Eckhaus, Donald Grube, George Christoffersen
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Publication number: 20160136056Abstract: A medication alarm, dispenser and records archive system and apparatus for providing interactive alert and informational functions in conjunction with a partitioned medication receptacle. Such an interactive medication receptacle system comprises an interactive electronic section slidably disposed on a pill storage section. The storage section includes a plurality of discrete compartments, each labeled with a day of the week. The electronic section includes an electronic touch screen with its front surface, a USB receptacle on its top side, and a processing housing that extends internally across the entire width of the top of electronic section and includes the primary operative computer components of the interactive medication receptacle system. The entire internal area of the electronic section below the processing housing is substantially hollow, thereby enabling it to slide over and encase the storage section.Type: ApplicationFiled: November 13, 2014Publication date: May 19, 2016Inventor: Shannon Lee Lapham
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Publication number: 20160136057Abstract: A controlled food intake system includes an apparatus having an inlet tube configured to connect to a lower esophageal stoma, a flow controller, and at least one container configured to detachably attach to the inlet tube and to administer nutrition liquids to a patient at a flow rate based on a position of the flow controller. The apparatus also includes an outlet tube configured to connect to an upper esophageal stoma and a waste container that detachably attaches to the outlet tube. Processing circuitry of the apparatus is configured to control the flow controller to control the flow rate of the nutrition liquids being administered to the patient based on prescribed nutrition intake order. The controlled food intake system also includes at least one server configured to generate reports based on the nutrition liquids administered to the patient and substance consumed by the patient.Type: ApplicationFiled: November 19, 2014Publication date: May 19, 2016Applicant: UMM AL-QURA UNIVERSITYInventor: Muhammad ARIF
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Publication number: 20160136058Abstract: A system for filling a root canal of a tooth and for covering pulp, with a silicone material comprising MxOy, where MxOy is selected from the group comprising CaO, BaO, MgO, Na2O, K2O, and SrO, especially preferably CaO; and/or at least one compound containing MxOy, where MxOy is selected from the group comprising CaO, BaO, MgO, Na2O, K2O, and SrO, especially preferably a compound containing CaO, in particular a compound containing CaO/SiO2. Such compositions exhibit bioactive properties and improve the ease of use and the prognosis for success of the system, according to the present invention, for filling a root canal and for covering pulp.Type: ApplicationFiled: June 18, 2014Publication date: May 19, 2016Inventors: Martin SCHLÜTER, Benjamin EZEH, Werner MANNSCHEDEL
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Publication number: 20160136059Abstract: The invention relates to a dental composition comprising—filler (F1) comprising aggregated nano-sized particles in an amount of from about 30 to about 70 wt. %, —filler (F2) comprising agglomerated nano-sized particles in an amount from about 1 to about 20 wt. %, —hardenable component (A1) being an urethane(meth)acrylate with a functionality of at least 2 and having a molecular weight from about 400 to about 3,000 g/mol, —hardenable component (A2) being a radically polymerizable (meth)acrylate with a functionality of at least 2 being different from component (A1), —redox curing initiator system, the dental composition not comprising non-agglomerated nano-sized filler in an amount above about 10 wt. %, wt. % with respect to the weight of the whole composition. The dental composition is in particular useful as or for production of permanent crown and bridges, inlays, onlays and veneers.Type: ApplicationFiled: July 1, 2014Publication date: May 19, 2016Inventors: Reinhold Hecht, Uwe H. Hoheisel, Adrian S. Eckert, Bernhard Hofmann
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Publication number: 20160136060Abstract: Disclosed is a water-based gel cosmetic composition comprising at least one polysaccharide hydrocolloid; at least one viscosity increasing agent different from the at least one polysaccharide hydrocolloid; at least one film forming polymer; at least one liquid fatty substance; optionally at least one nonionic surfactant having an HLB greater than or equal to about 15; water; at least one pH or cation adjuster; and optionally a pigment. Also disclosed are methods of making up the eyes with the composition of the invention as well as a method of making the composition.Type: ApplicationFiled: November 13, 2014Publication date: May 19, 2016Inventors: Christine Marie CRANE, Angeles FONOLLA-MORENO
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Publication number: 20160136061Abstract: Inventive embodiments disclosed herein relate to gel volume mascara. The mascara includes water in a concentration of at least about 45% by weight; disodium ethylenediaminetetraacetate; Polysorbate 20; Black iron oxide; One or more waxes selected from the group consisting of beeswax, Cera Carnauba/Copernicia Cerifera (Carnauba) Wax/CIRE de Carnauba, and paraffin in a concentration of 15-20% by weight; and a synthetic layered silicate, insoluble in water, in a concentration effective for forming a colloidal dispersion with the water.Type: ApplicationFiled: January 25, 2016Publication date: May 19, 2016Inventors: Nykol Allen, Julianne Sortino
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Publication number: 20160136062Abstract: The present invention relates to the cosmetic use of a cold atmospheric plasma for preventing and/or treating aesthetis disorders of the healthy scalp.Type: ApplicationFiled: June 20, 2014Publication date: May 19, 2016Applicant: L'OREALInventors: Frédéric WOODLAND, Fabrice OSOLIN, Jean-Yves LEGENDRE, Gabin VIC
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Publication number: 20160136063Abstract: The present invention relates to a cosmetic composition comprising: (i) at least one oxide of an alkaline earth metal, (ii) at least one carboxylic acid having a pKa equal to or greater than 3.5, and (iii) an aqueous phase. The cosmetic composition according to the present invention can provide a long-wear effect, especially a long-wear makeup effect.Type: ApplicationFiled: July 8, 2014Publication date: May 19, 2016Inventor: Rui NIIMI
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Publication number: 20160136064Abstract: Present invention relates to an aqueous oxidizing composition for hair which makes possible achieving homogeneous coloration of multiple damaged hair and especially provides excellent grey coverage with oxidative hair dyes. The object of the invention is an aqueous oxidizing composition for hair comprising one or more oxidizing agent, one or more polyol, one or more oil, one or more solid fatty alcohol and one or more surfactant wherein fatty alcohol to oil weight ratio is less than 1, weight ratio of surfactant to sum of fatty alcohol and oil is less than 0.Type: ApplicationFiled: December 13, 2013Publication date: May 19, 2016Applicant: KAO GERMANY GMBHInventors: Anja ÄCHTNER, Axel BALKE, Ovidiu FEIER-IOVA, Carsten HÄCKL, Clarissa LIPINSKI, Jonathan WOOD
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Publication number: 20160136065Abstract: The invention provides an oral care product suitable for the remineralisation of teeth, the product comprising: (i) a first composition having a non-aqueous liquid continuous phase including a thickening agent, a humectant, and an agent for the remineralisation of teeth; the agent for the remineralisation of teeth being a mixture of a calcium source and a phosphate source which, when delivered to the teeth results in the in situ generation of hydroxyapatite on teeth; (ii) a second composition having an aqueous liquid continuous phase including a thickening agent and a humectant, the second composition comprising at least 30% by weight water (by weight based on the total weight of the second composition), and less than 2.Type: ApplicationFiled: June 27, 2014Publication date: May 19, 2016Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Cinzia BRIGNOLI, Kate HORNBY, Andrew JOINER, Carole Jane PHILPOTTS
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Publication number: 20160136066Abstract: An aqueous composition comprising an aluminium sesquichlorohydrate salt, water soluble calcium salt, and amino acid, wherein the molar ratio of water soluble calcium salt to aluminium is at least 1:40 and the molar ratio of amino acid to aluminium is at least 1:20 and methods for making such compositions having enhanced antiperspirancy performance.Type: ApplicationFiled: November 19, 2014Publication date: May 19, 2016Inventors: Kevin Ronald FRANKLIN, Philip Christopher WATERFIELD, Karim Mohamed Anwar M FAWZY
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Publication number: 20160136067Abstract: A prophylactic cream, ointment or deodorant for the prevention of the formation of yeast infections.Type: ApplicationFiled: July 30, 2015Publication date: May 19, 2016Inventor: Shirley Johnson
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Publication number: 20160136068Abstract: The present invention relates to a process for the oxidation dyeing of keratin fibres implementing: a) a step of pretreating said fibres by application to said fibres of a cosmetic composition (B) comprising: i) at least one fatty substance in an amount of greater than or equal to 10% by weight relative to the total weight of the composition (B); and ii) at least one metal catalyst; b) optionally a washing, rinsing, drying and/or rubbing-dry step; c) followed by a step of dyeing by application to said fibres of a cosmetic composition (A) comprising: i) at least one oxidation base, preferably chosen from para-phenylenediamines, bis(phenyl)alkylenediamines, para-aminophenols, ortho-aminophenols, heterocyclic bases preferably comprising at least two nitrogen atoms, and addition salts thereof; ii) optionally at least one coupler; and iii) at least one chemical oxidizing agent.Type: ApplicationFiled: June 19, 2014Publication date: May 19, 2016Inventors: Marie MIGNON, Marie Giafferi, Marie CRETTE, Leïla HERCOUET, Henri SAMAIN
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Publication number: 20160136069Abstract: The subject of the present invention is a process for the oxidation dyeing of keratin fibres, in particular human keratin fibres such as the hair, implementing: a) a step of treating said fibres by application to said fibres of a cosmetic composition (A) comprising: i) at least one fatty substance in an amount of greater than 10% by weight relative to the total weight of the composition (A), at least one metal catalyst; ii) at least one coupler; iii) optionally at least one oxidation base, preferably chosen from para-phenylenediamines, bis(phenyl)alkylenediamines, para-aminophenols, ortho-aminophenols, heterocyclic bases, addition salts thereof and solvates thereof; b) optionally a washing, rinsing, drying and/or rubbing-dry step; c) a step of treatment by application to said fibres of an oxidizing cosmetic composition (B) comprising at least one chemical oxidizing agent; and it being understood that steps a), b) and c) can be carried out successively a), then b), then c), or else a) then c), followed by b).Type: ApplicationFiled: June 19, 2014Publication date: May 19, 2016Inventors: Leïla HERCOUET, Marie MIGNON, Henri SAMAIN, Alain LAGRANGE
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Publication number: 20160136070Abstract: Described herein are methods and compositions useful for enhancing pigmentation, such as skin, eye and/or hair pigmentation comprising administering e.g., an NNT inhibitor or an agent that modifies redox status in a melanocyte.Type: ApplicationFiled: November 16, 2015Publication date: May 19, 2016Applicant: THE GENERAL HOSPITAL CORPORATIONInventors: Elisabeth Maria ROIDER, David Erich FISHER
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Publication number: 20160136071Abstract: Bimatoprost, a prostamide F2 alpha analog, used alone or in combination with other prostamides, or prostaglandin analogs, in a topical manner for the promotion of hair growth in mustache, beard, chest and other androgen dependent hair growth areas in humans and animals.Type: ApplicationFiled: June 12, 2013Publication date: May 19, 2016Inventor: Edward Dunne Corboy, JR.
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Publication number: 20160136072Abstract: The invention relates to N-alkyl-N-acylglucamines of formula (I) suitable as a component in skin-cleaning agents and hand dishwashing agents, which comprise an aqueous surfactant system with at least one anionic surfactant, wherein, in formula (I), Ra is a linear or branched, saturated or unsaturated C5-C21 alkyl radical, preferably a C11-C17 alkyl radical, and Rb represents a C1-C4 alkyl radical, preferably methyl; the N-Alkyl-N-acylglucamines (I) containing at least 8 wt. %, based on the total amount of N-alkyl-N-acylglucamines (I), of compounds with a mono- or polyunsaturated C18 fatty acid radical Ra—CO—.Type: ApplicationFiled: June 25, 2014Publication date: May 19, 2016Applicant: Clariant International Ltd.Inventors: Peter KLUG, Carina MILDNER, Henrike NEUHOFF
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Publication number: 20160136073Abstract: Compositions including a discontinuous oil phase homogeneously dispersed in a continuous water phase, the oil phase containing a sunscreen agent that includes a polymer composition containing a linear, ultraviolet radiation absorbing polyether, the linear, ultraviolet radiation absorbing polyether including a chemically bound UV-chromophore; and an oil-in water emulsifier component including an anionic oil-in-water emulsifier in an amount such that the composition includes about 0.5 percent by weight to about 3 percent by weight of the anionic oil-in-water emulsifier.Type: ApplicationFiled: January 27, 2016Publication date: May 19, 2016Applicant: Johnson & Johnson Consumer Inc.Inventor: Susan Daly
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Publication number: 20160136074Abstract: Compositions including a discontinuous oil phase homogeneously dispersed in a continuous water phase, the oil phase including a sunscreen agent that includes a linear, ultraviolet radiation absorbing polyether that comprises a chemically bound UV-chromophore; and an oil-in water emulsifier component including an anionic oil-in-water emulsifier and a nonionic oil-in-water emulsifier having an alcohol functional group, wherein the weight ratio of the anionic oil-in-water emulsifier to the nonionic oil-in-water emulsifier is about 12 or less and wherein the linear, ultraviolet radiation absorbing polyether is present in an amount effective to provide the composition with an SPF of about 10 or greater.Type: ApplicationFiled: January 27, 2016Publication date: May 19, 2016Applicant: Johnson & Johnson Consumer Inc.Inventor: Susan Daly
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Publication number: 20160136075Abstract: Disclosed herein are teeth whitening compositions generally including an oxidizing agent, and an activating agent that has an emission wavelength between about 400 nm and about 570 nm. Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.Type: ApplicationFiled: January 26, 2016Publication date: May 19, 2016Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI
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Publication number: 20160136076Abstract: Novel retinoic acid derivatives and a process for their preparation are described.Type: ApplicationFiled: June 17, 2014Publication date: May 19, 2016Inventors: Mauro GABOARDI, Graziano CASTALDI, Lars FREDRIKSSON
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Publication number: 20160136077Abstract: The invention relates to a process for dyeing keratin fibres, comprising the use of one or more metal catalysts and of a composition (A) comprising: —one or more oxidizing agents, and —at least one aminobenzimidazole oxidation base of formula (I) in which the radicals R1 to R5 represent, independently of each other, a hydrogen atom; a halogen atom; a C1-C6 alkyl radical; a C1-C6 alkoxy radical; a C1-C6 dialkylamino radical; a carboxylic radical (—COOH); a sulfonic radical (—S03H); a phenyl radical; a sat orated or unsaturated 5- to 7-membered heterocyclic radical, comprising one or more heteroatoms chosen from N, O and S.Type: ApplicationFiled: June 23, 2014Publication date: May 19, 2016Inventors: Boris LALLEMAN, Alain LAGRANGE, Marie MIGNON
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Publication number: 20160136078Abstract: This invention discloses a method for stabilizing ascorbic acid derivatives and the application thereof. The mentioned method comprises mixing ascorbic acid derivative with a non-water-in-oil composition, and the composition comprises buffer, phosphonic acid derivative and at least one alcohol. The yellowish and degradation of ascorbic acid derivative can be efficiently decreased by the mentioned method. Moreover, the mentioned method can be used in topical composition, such as toner, serum, lotion, cream.Type: ApplicationFiled: January 27, 2016Publication date: May 19, 2016Inventors: Lin-Chao Chen, Yu-Ling Shiu, Chia-Pei Lee, Chao-Yang Lee
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Publication number: 20160136079Abstract: The present invention relates to compositions and methods for modulating melanin production, secretion and/or accumulation in human skin cells. In particular, the present invention relates to the use of A3 adenosine receptor antagonists in compositions and methods for the treatment and amelioration of hyper-pigmentation conditions and for the lightening of skin, and to the use of A3 adenosine receptor agonists in compositions and methods for the treatment and amelioration of hypo-pigmentation conditions and for the tanning of skin.Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Applicant: ORADIN PHARMACEUTICAL LTD.Inventors: Lea Levana MADI, Rafi KORENSTEIN
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Publication number: 20160136080Abstract: The disclosed technology relates to a multi-functional additive for personal-care and cosmetic product applications, more particularly, a naturally derived multifunctional additive for use in skin-care formulations, which provides steric stabilization of pigment particles and/or emulsion droplets in aqueous compositions, good suspension-stability (i.e., against settling/creaming) of the compositions, and increased utilization of particulate, skin-care benefit agents contained in the compositions.Type: ApplicationFiled: June 17, 2014Publication date: May 19, 2016Inventors: Ashoke K. Sengupta, Eric H. Anderson
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Publication number: 20160136081Abstract: An oral care composition in the form of a toothpaste, tooth gel, dentifrice, tooth powder, prophy paste, mouthwash, rinse, tooth mousse, dental floss, chewing gum, soluble oral care strip or film for direct application or attachment to an oral surface, or lozenge for combating dental caries, erosion, hypersensitivity, and/or staining that includes an orally acceptable carrier and a copolymer of a first ?,?-ethylenically unsaturated phosphate compound (A); and one or more ?,?-ethylenically unsaturated co-monomers, at least one of which is other than an allyl-functional co-monomer, wherein (A) is an allyl phosphate compound of formula (A): [CH2?CH—CH2—O(R1O)a(R2O)b]xP(O)(OM)3-x ??(A) wherein, R1 is a substituted or unsubstituted (C2-C4) alkylene moiety; R2 is a substituted or unsubstituted (C2-C4) alkylene moiety; M is identical or different, hydrogen, alkali metal, ammonium, protonated alkyl amine, protonated alkanolamine, or protonated basic amino acid; X is 1 or 2, a is from 1 to 20; and b is from 0 to 20Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Applicant: RHODIA OPERATIONSInventors: Robert Lee REIERSON, Denis BENDEJACQ
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Publication number: 20160136082Abstract: Cosmetic compositions are provided, which are capable of having a tightening and/or curling effect on a human integument when applied thereto. Cosmetic compositions according to the invention typically include a cosmetically acceptable vehicle and a pH-dependent film-forming polymer of either a poly(methacrylic acid-co-methyl methacrylate) or a poly(methacrylic acid-co-ethyl acrylate). The tightening and/or curling effect of these cosmetic compositions is prolonged and substantially resistant to environmental stresses such as increased heat or humidity.Type: ApplicationFiled: January 19, 2016Publication date: May 19, 2016Applicant: Avon Products, Inc.Inventors: Ashley L. Howell, Bing C. Mei
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Publication number: 20160136083Abstract: The invention provides personal care products that do not contain D4 and/or D5 cyclomethicones but which do have the skin feel, spreadability, and other physical and chemical characteristics of personal care products that do contain these cyclomethicones. The products of the invention include a neopentyl polyol polyester(s) derived from neopentyl glycol, an isoparaffin(s), and a personal care formulation. Also included are replacement compositions for use in personal care products (so that D4 and D5 cyclomethicones can be excluded from the formulation) and methods of preparing personal care products and replacement compositions.Type: ApplicationFiled: January 26, 2016Publication date: May 19, 2016Inventors: Daniel Winn, Marvin Goldberg, Lawrence B. Moss
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Publication number: 20160136084Abstract: The present invention relates to a composition for treating keratin fibres, comprising at least an aqueous dispersion of hybrid hydrophobic film-forming acrylic polymer particles and at least one amino silicone and also to a process for treating keratin fibres using such a composition.Type: ApplicationFiled: June 18, 2014Publication date: May 19, 2016Inventor: Karen TEBOUL
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Publication number: 20160136085Abstract: Disclosed are water-based wax free liquid cosmetic compositions comprising a synthetic thickening polymer, a natural thickening polymer, at least one nonionic surfactant, film forming polymers and polyurethane polymer. The ratio of the synthetic thickening polymer to the natural thickening polymer is ratio is less than or equal to 4:1.Type: ApplicationFiled: November 13, 2014Publication date: May 19, 2016Inventors: Christine Marie CRANE, Angeles FONOLLA-MORENO
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Publication number: 20160136086Abstract: Disclosed is a topical skin composition and methods for its use. The composition can include Silybum marianum fruit extract, Momordica grosvenorii fruit extract, and a cosmetic vehicle comprising water, a moisturizing agent, and a preservative.Type: ApplicationFiled: January 20, 2016Publication date: May 19, 2016Inventors: Tiffany Florence, Michelle Hines, David Gan, Barbara Durkee
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Publication number: 20160136087Abstract: The present invention generally relates to compositions and methods for topical or transdermal delivery, e.g., for affecting mood states. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.Type: ApplicationFiled: January 22, 2016Publication date: May 19, 2016Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Publication number: 20160136088Abstract: This invention relates to a silica hydrogel composite obtainable by mixing silica particles, comprising an encapsulated agent, with a silica sol, wherein obtained hydrogel composite is shear-thinning. The present invention also relates to use of the silica hydrogel composite according to the invention for an injectable, flowing or extrudable formulation. The present invention further relates to a method for preparing the silica hydrogel.Type: ApplicationFiled: June 18, 2014Publication date: May 19, 2016Applicant: DelSiTech OyInventors: Mika JOKINEN, Harry JALONEN, Ari-Pekka FORSBACK
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Publication number: 20160136089Abstract: This invention relates to therapeutic compositions, particularly sprayable aqueous compositions, and unit dose formulations comprise ketorolac or a pharmaceutically acceptable salt, alone or in combination with lidocaine or a pharmaceutically acceptable salt thereof. The compositions are nasally administered to a subject in need thereof to treat pain or inflammation.Type: ApplicationFiled: November 20, 2015Publication date: May 19, 2016Applicant: EGALET US, INC.Inventors: Roger Whiting, Ramachandran Thirucote
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Publication number: 20160136090Abstract: This invention relates to a gel formulation for nasal administration of a controlled release formulation of hormones to the systemic circulation and/or to the brain. The special lipophilic or partly lipophilic system of the invention leads to higher bioavailability of the active ingredient caused by sustained serum levels in plasma but also leads to a more favorable serum level profile. The special lipophilic or partly lipophilic system also allows for the modulation of brain functioning. The invention also relates to the nasal administration of steroid hormones for treatment of female sexual dysfunction (FSD) or female arousal disorder.Type: ApplicationFiled: December 10, 2015Publication date: May 19, 2016Applicant: MATTERN PHARMA AGInventor: Claudia Mattern
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Publication number: 20160136091Abstract: Disclosed is an orally disintegrating tablet including: (a) an active ingredient; (b) a starch with an amylose content of 20% by mass to 30% by mass and a degree of gelatinization of less than 10%; and (c) at least one inorganic excipient selected from the group consisting of magnesium silicate, calcium silicate, and synthetic hydrotalcite. The orally disintegrating tablet is a single-layer tablet or a dry-coated tablet having an inner core and an outer layer. The orally disintegrating tablet as a single-layer tablet or the outer layer of the orally disintegrating tablet as a dry-coated tablet has a crystalline cellulose content of 0% by mass to 5% by mass.Type: ApplicationFiled: July 17, 2014Publication date: May 19, 2016Applicant: SANWA KAGAKU KENKYUSHO CO., LTD.Inventors: Masahiro Kondo, Naoya Ochiai, Yuki Sakakura
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Publication number: 20160136092Abstract: The invention relates to stereospecific lipids for the locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems. A preferred embodiment thereof is a thermosensitive liposome for treating tumors, especially urinary bladder tumors and other localized tumors.Type: ApplicationFiled: June 18, 2014Publication date: May 19, 2016Applicant: THERMOSOME GmbHInventor: Hansjörg Eibl
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Publication number: 20160136093Abstract: An engineered aerosol particle for use in aerosol applications is provided. The engineered aerosol particle comprises a fabricated nanoparticle body member being non-spherical. The fabricated nanoparticle body member is configured to provide at least one of auto-rotation, tumbling, or lift when entrained in an airstream to thereby increase settling time of the fabricated nanoparticle body member. An associated method is also provided.Type: ApplicationFiled: July 27, 2015Publication date: May 19, 2016Inventors: Philip DeSimone, Benjamin Maynor, Mary Napier, Jonathan Pillai, Joseph M. DeSimone, Will Patrick, Kyle Laaker, Hanjun Zhang
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Publication number: 20160136094Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.Type: ApplicationFiled: November 11, 2015Publication date: May 19, 2016Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, PATRICK A. ARMSTRONG, XI CHEN
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Publication number: 20160136095Abstract: Provided herein are methods for treating epilepsy or seizure disorders comprising administering a composition to a subject, the composition comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier.Type: ApplicationFiled: November 17, 2015Publication date: May 19, 2016Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, PATRICK A. ARMSTRONG, XI CHEN
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Publication number: 20160136096Abstract: Compositions and methods of making and using of microparticle compositions that provide faster flow or improved injectability through smaller or small-diameter needles have been developed. Notably, the microparticle compositions can be successfully delivered or administered through smaller-diameter needles than other microparticle compositions prepared from biocompatible or biodegradable polymers including, for example, poly(lactide), poly(lactide-co-glycolide), polycaprolactone, or poly-3-hydroxybutyrate. The microparticle compositions can exhibit a higher solids loading for a given needle size and/or faster flow through needles than other microparticle compositions. Further, blending or mixing the polymer of the microparticle composition with other polymer formulations can enhance the injectability of the resulting formulation.Type: ApplicationFiled: December 3, 2015Publication date: May 19, 2016Inventors: Peter Markland, Gary Anthony Winchester, Thomas Robert Tice, David P. Martin
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Publication number: 20160136097Abstract: An object of the present invention is to provide an orally disintegrating tablet (ultrafast-disintegrating tablet) having an extremely high disintegrability (short disintegration time), and a high tablet hardness, and to provide a simple method for the production of said ultrafast-disintegrating tablet without such a complicated process as freeze-drying. This invention relates to an orally disintegrating tablet comprising a first disintegrator component of an acid-type carboxymethylcellulose, and having a tablet hardness of 10 N or more and a disintegration time in water of less than 15 seconds, a method for the production of said orally disintegrating tablet, and to a disintegrative particulate composition for use in said method.Type: ApplicationFiled: July 4, 2014Publication date: May 19, 2016Inventors: Takahiro HIRAMURA, Sae ITAYA, Naohiro HASHIKAWA, Tomohito OKABAYASHI, Anan SAKAGUCHI
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Publication number: 20160136098Abstract: The present invention is directed to coprocessed excipient particles comprising a cellulosic material such as microcrystalline cellulose in intimate association with silicon dioxide, a disintegrant and a polyol, sugar or a polyol/sugar blend. The excipient particles display good processing and are useful in prepared compressed solid dosage forms that exhibit rapid disintegration (less than about 60 seconds) when placed on the tongue or when tested according USP disintegration testing, while still providing acceptable mouth feel.Type: ApplicationFiled: January 27, 2016Publication date: May 19, 2016Applicant: JRS PharmaInventors: David SCHAIBLE, Louis Mejias
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Publication number: 20160136099Abstract: The present invention relates to a process for producing monolithic tablets. The method employs a melt-processed composition containing at least on active agent and at least one thermoplastic binder. The invention further relates to a method for cutting and deflashing a belt of pre-shaped bodies of a melt-processed composition, wherein the pre-shaped bodies are interconnected by flash.Type: ApplicationFiled: January 21, 2016Publication date: May 19, 2016Inventors: Soumojeet Ghosh, Didier Lefebvre, Bryan Wiesner, Kevin Novak, Thomas Kessler
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Publication number: 20160136100Abstract: A multi-compartment capsule, comprising, a first receiving chamber comprising at least one ingredient having a first physical state, wherein said ingredient is selected from the group consisting of a nutraceutical, a vitamin, a dietary supplement and a mineral; and a second receiving chamber comprising at least one ingredient having a second physical state, wherein said ingredient is selected from the group consisting of a nutraceutical, a vitamin, a dietary supplement and a mineral; wherein said first physical state of said ingredient of said first receiving chamber being different from said second physical state of said ingredient of said second receiving chamber; and said ingredient of said first receiving chamber being different from said ingredient of said second receiving chamber.Type: ApplicationFiled: January 25, 2016Publication date: May 19, 2016Inventor: Fred H. Miller
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Publication number: 20160136101Abstract: The invention relates to gastro-resistant soft shell capsules having a capsule shell comprising high acyl gellan gum, at least one starch and at least one plasticizer, wherein the capsules fulfil pharmacopoeial disintegration tests characterizing the capsules as gastro-resistant dosage forms. The invention further relates to a method for manufacturing such gastro-resistant soft shell capsules.Type: ApplicationFiled: June 20, 2014Publication date: May 19, 2016Applicant: SWISS CAPS RECHTE UND LIZENZEN AGInventors: Georg SYDOW, Markus SENNHAUSER, Burkhard SCHLUETERMANN, Armin PRASCH, Rainer NEHRING