Abstract: Connector assemblies are provided for controlling flow in a fluid line that include an outer shell, an inner housing, and a tubular member. The inner housing is disposed within the outer shell and includes a boss disposed adjacent a first end of the outer shell. The inner housing is movable axially within the outer shell between first and second positions when a device is connected to the first end. The tubular member is carried by the inner housing and includes a fluid passage extending between a second end of the outer shell. The tubular member moves axially as the inner housing moves between the first and second positions, and cam features on the outer shell and the tubular member cause the tubular member to rotate as the inner housing moves between the first and second positions, thereby opening a fluid path between the fluid passage and the first end.

Abstract: A connector provided with a housing which defines an insertion section into which a male connector is inserted from the outside and a flow path communicating with the insertion section and an elastic valve body which has a slit and blocks the insertion section. The housing includes a tip receiving section formed on an inner wall defining the flow path, the tip receiving section receiving a tip of the male connector inserted through the slit of the elastic valve body. The tip receiving section is formed on only a part of the inner wall in a cross section that is perpendicular to an insertion direction of the male connector and includes at least a part of the tip receiving section.

Abstract: A sensor device for use in a medical fluid delivery system, or an infusion pump device, comprises a fluidic chamber with a deformable cover closing at least an area of the chamber and an optical detection system comprising at least one light emitter for emitting one or more incident light beams and a sensor unit for monitoring one or more reflected light beams is presented. In a pressurized state of the fluidic chamber, the deformable cover is deformed such that it forms an inflexion point area within the deformed cover. The one or more incident light beams emitted by the light emitter are directed on the cover such that the one or more incident light beams are reflected essentially in the inflexion point area.

Abstract: An adjusting device for adjusting the flow rate of a medicinal fluid-conveying system, said device having a selection wheel for selecting one of a number of possible flow rates, having an adjusting disc connected to said selection wheel for adjusting the selected flow rate, and having a catching nose that cooperates with the outer edge of the adjusting disc, is improved in that the adjusting disc has a star shape.

Abstract: A system for controlling an environment of a patient undergoing a surgical procedure is provided. The system includes a conduit configured to channel fluids towards the patient, a sensor configured to measure at least one operating parameter of the fluid being channeled to the patient, an effector configured to change the operating parameter of the fluid, and a controller configured to selectively activate the effector based on a signal received from the sensor.

Abstract: A method of dispensing fluid includes three processes. A first one of these processes includes pumping fluid into a resilient variable-volume dispensing chamber. The dispensing chamber is in series with a normally present finite fluid impedance and an output. The impedance is sufficient so as to cause expansion of the dispensing chamber as it receives pumped fluid even while some fluid flows through the output. Another one of these processes includes repeatedly measuring a parameter related to volume of the dispensing chamber over time. A third one of these processes includes controlling the pumping of fluid based on repeated measurements of the parameter to produce a desired fluid flow through the output. A corresponding system for dispensing fluid implements these processes.

Abstract: A medication control method includes: a medication instruction step in which an instruction to perform medication to a living body is given; a biological information gathering instruction step in which an instruction to perform an operation of detecting biological information that can change due to the medication as a factor and gathering the biological information as monitoring information is given; and an instruction step in which one of the medication instruction step and the biological information gathering instruction step is inhibited or postponed if a period of detection of the biological information carried out according to the biological information gathering instruction step and a period during which the medication carried out according to the medication instruction step influences the detection of the biological information coincide with each other.

Abstract: The present invention relates to an assembly for a drug delivery device comprising a dispensing container and a reservoir container for holding a fluid medicinal product, wherein the dispensing container and the reservoir container are connected to one another and are in fluid communication, and wherein the dispensing container is squeezable for dispensing a dose of the fluid medicinal product from the dispensing container, the dispensing container being refillable with the fluid medicinal product from the reservoir container.

Abstract: An automatic injection syringe that is pre-loaded with medicament and protected from inadvertent ejection of said medicament or injection of air. A plunger assembly is first positioned with a compressed spring in between a plunger and a retainer element. The compressed spring is held in place by a resilient retainer sleeve and the plunger is inside the syringe tube. When the syringe is pushed back, the resilient retainer sleeve releases the spring which then expands to push the plunger into the reservoir of the syringe tube to eject the medicament out from a syringe needle.

Abstract: A disinfecting cap accepts a needleless injection site to apply an antiseptic agent. The cap includes a breakable seal located in a chamber between the proximal and distal portions so as to be spaced away from the opening. The cap body may include a compliant wall that deforms when a needleless injection site is inserted into the opening to removably hold the cap on the needleless injection site. In lieu of a compliant wall, a flexible skirt may extend from the cap body into the proximal portion, so that when a needleless injection site is inserted into the opening, the flexible skirt engages the outer diameter of the needleless injection site to removably hold the cap on the needleless injection site. A carrier strip may be used, wherein each of the plurality of disinfecting caps is removably attached at its proximal end to the carrier strip.

Abstract: A medication delivery device included molded cylindrical barrel having visual marks on the surface of the barrel in the axial direction, a plunger seals the distal opening of the cylindrical barrel, a molded needle hub disposed in the proximal opening of the cylindrical barrel for sealing the needle hub to the barrel. A needle is disposed in the needle hub for communicating liquids by operation of the plunger in the axial direction. The circumferential surface on the flange of the needle hub comprises a colored mark that corresponds to a characteristic of the medication delivery device or its contents.

Abstract: An applicator includes a syringe , a liquid agent injection unit provided at one end of the syringe and in communication with a liquid agent flow passage, a pusher slidably inserted from an opposite end of the syringe, a push portion at an end of the pusher opposite from a syringe side of the pusher that is inserted in the syringe and causing the liquid agent to be injected from the liquid agent injection unit by being pushed, a gas flow passage formed in a support unit supplies compressed gas to the liquid agent injection unit, and an operation unit causes a start of the supply of the compressed gas to the liquid agent injection unit. The push portion allows an operator to push the push portion with a thumb of a hand engaging the operation unit with at least one finger other than this thumb.

Abstract: A drive mechanism for a delivery device or a positioning mechanism comprising a rod (5), a rotatable cam member (9), and a follower member (6) being coupled to the cam member (9) in such a manner that a rotation of the cam member (9) is transferred to a reciprocating movement of the follower member (6) or a part thereof (7), the follower member (6) being coupled to the rod (5) via a ratchet mechanism (62, 64) in such a manner that the reciprocating movement of the follower member (6) or the part thereof (7) drives the rod (5).

Abstract: A syringe assembly includes a syringe barrel having a tubular body that bounds a compartment extending between a proximal end and an opposing distal end and a flange that radially outwardly projects from the proximal end of the body. A stopper is movably disposed with the compartment of the syringe barrel. A plunger rod includes a shaft having a proximal end and an opposing distal end and a plurality of teeth disposed on the shaft, the distal end of the shaft being secured to the stopper. A backstop engages the flange of the syringe barrel and at least a portion of the plurality of teeth of the plunger rod.

Abstract: A syringe adapter attaches to the syringe to prevent contamination of the fluid. After a withdrawal of sterile fluid in a syringe from a prescription bottle, the adapter may be attached to the syringe to prevent contamination of the fluid. The fluid may then be safely injected into the patient's body or used for bladder irrigation.

Abstract: A supplemental device for use with an injection device, the supplemental device comprising: a plurality of light sources each being configured to illuminate a surface portion of an injection device, in use, with light of a different wavelength; at least one sensor for generating sensor outputs indicative of the respective intensities of light of different wavelengths reflected from the surface portion; and a processor for: controlling the plurality of light sources to illuminate the surface portion with light of first to third different wavelengths; obtaining first to third values for sensor outputs corresponding to the first to third different wavelengths respectively; performing one or more calculations using at least the first and second values to provide one or more further values; and using the third value and the or each further value, but not the first and second values, to determine a property of the injection device.

Abstract: Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one pawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.

Abstract: The present invention discloses a pressure-depending clutching device for locating and safely positioning a needle in a body cavity. The device is capable of automatically engaging and disengaging the needle from a driving force depending on the pressure experienced by needle. The device has a body with an interior space, a pressure-sensing element disposed in the body defining a portion of a pressure chamber, and a force-receiving element operatively connected to the pressure-sensing element. The force-receiving element has a shape complimentary to a portion of a force-sending element operatively connected to a force-applying structure such as a handle for a user to apply a driving force. The pressure-sensing element, the force-receiving element, and the complementary force-sending element form a driving force engaging mechanism for coupling the force-applying structure to the needle during operation.

Abstract: The present invention relates to a medicament delivery device comprising a generally tubular distal housing part (10; 110) having opposite proximal and distal ends, wherein third mechanically coded interface means (11; 111) are arranged on its proximal end; a generally tubular proximal housing (20; 120) part having opposite proximal and distal ends and being releasibly connected to said distal housing part, wherein with fourth mechanically coded interface means (22; 122) are arranged on its distal end; a medicament container having a slidable stopper, wherein said container is arranged to be positioned within said proximal housing part; a plunger rod (60; 160) arranged within said distal housing; drive means arranged within said distal housing and being operably connected to said plunger rod for driving said plunger rod and thereby said stopper towards the proximal end of the device; wherein said device further comprises an interface member (50; 150) comprising first (51; 151) and second (52; 152) mechanicall

Abstract: The present disclosure relates to a counting mechanism (2) for a drug delivery device (1) comprising a first counting member (4) arranged for displaying a counted number and being biased to move in a first rotational direction and a connecting member (5) having a dose setting position and a dose dispensing position, wherein, in the dose setting position, the connecting member (5) impedes a rotation of the first counting member (4) in the first rotational direction, and wherein, in the dose dispensing position, the connecting member (5) permits the first counting member (4) to rotate in the first rotational direction.

Abstract: Describe is an autoinjector (1) comprising a case (2) adapted to hold a medicament container having a needle (4), a needle shroud (7) telescopically coupled to the case (2) and movable between a first extended position (FEP) relative to the case (2) in which the needle (4) is covered and a retracted position (RP) relative to the case (2) in which the needle (4) is exposed, and a plunger (10) rotationally and slidably disposed in the case (2). The plunger (10) is rotatable relative to the case (2) between a first rotational position in which the plunger (10) is engaged to the case (2) and a second rotational position in which the plunger (10) disengages the case (2). The needle shroud (7) is operably coupled to the plunger (10). When the needle shroud (7) translates from the first extended position (FEP) to the retracted position (RP), the plunger (10) rotates from the first rotational position to the second rotational position.

Abstract: A prefilled medical injection device with production specific elements is provided as a single use disposable injection device that is optimally suited for mass production through the Blow Fill Seal manufacturing process. The device utilizes a valve and a needle assembly fused to an insert. The valve and the needle assembly are positioned within the insert forming a conduit. The needle assembly is covered with a needle cap that is detachably coupled to protecting the needle assembly from contamination and a user from accidental needle stick. The insert is engaged to the bellows during the BFS manufacturing process and hermetically sealed by a paris on layer that covers exterior portion of the insert and the needle cap. The parison layer is formed and trimmed creating exterior features that facilitate the use of the prefilled medical injection.

Abstract: The invention relates to an activator unit for an autoinjector, comprising a substantially cylindrical housing (3) in which an axially movable pressure pin (4) is guided, said pressure pin being insertable counter to a spring unit and being lockable, when inserted, by means of detent projections (6) of a retaining element (5) that is connected to the pressure pin. The spring unit comprises a first coil spring (1) and at least one second coil spring (2) having a larger diameter than the first coil spring, the second coil spring being coaxial to the first coil spring.

Abstract: A front cap for a medicament delivery device having proximal and distal ends is configured to be releasably connected to the medicament delivery device and includes a shield grabber support and a shield grabber for connecting the front cap to an outer surface of a needle shield of a syringe positioned within the medicament delivery device. The shield grabber is coupled to the shield grabber support such that the shield grabber is axially movable relative to the shield grabber support.

Abstract: Described is an autoinjector (1) comprising a case (2) having a rib (2.9), a needle shroud (7) telescopically coupled to the case (2) and movable between a first extended position (EP), a retracted position (RP) and a locked second extended position (SEP), a carrier (8) slidably arranged in the case (2), adapted to hold a medicament container, and movable from a first axial position to a second axial position relative to the case (2), and a collar (16) rotatably and slidably disposed in the case (2) and coupled to the needle shroud (7) and the carrier (8). The collar (16) abuts the rib (2.9) when the needle shroud (7) is in the first extended position (EP) and the carrier (8) is in the first axial position, and the collar (16) disengages the rib (2.9) when the needle shroud (7) is in the retracted position (RP) and the carrier (8) is in the second axial position.

Abstract: A safety syringe assembly and a replaceable base unit are disclosed. The replaceable base unit of the present invention includes a base portion, a needle cover and a disengagement actuator. The base portion is configured to detachably connect with a syringe holder and has a through-hole structure, which is used to connect with an external needle. The needle cover's proximal end is connected with the base portion to allow the needle cover to move with respect to the base portion, enabling it to contain and cover the syringe needle. The disengagement actuator is configured on the base portion and disengages the base portion from the syringe holder in pressing mode.

Abstract: Described is an autoinjector (1) comprising a case (2) adapted to hold a medicament container having a needle (4), a needle shroud (7) telescopically coupled to the case (2) and movable between a first extended position (FEP) relative to the case (2) in which the needle (4) is covered, and a retracted position (RP) relative to the case (2) in which the needle (4) is exposed, and a second extended position (SEP) relative to the case (2) in which the needle (4) is covered and the needle shroud (7) cannot translate relative to the case (2), and a plunger (10) slidably disposed in the case (2) and movable between a proximal position, an intermediate position and a distal position relative to the case (2). When the plunger (10) is in the intermediate position and the needle shroud (7) is in the retracted position (RP), the plunger (10) abuts the case (2) to prevent the needle shroud (7) from returning to the exten ded position (EP).

Abstract: A method for warming infusion or transfusion fluids by an exothermic reaction of a reactive liquid using a warming device. The device comprises a reaction chamber and a secondary chamber. The reaction chamber and the secondary chamber are aligned end on and are abutting. The reaction chamber contains a trigger and the secondary chamber contains the reactive liquid. The exothermic reaction results when the reactive liquid contacts the trigger leading to crystallization of the reactive liquid. The secondary chamber is compressible. An inlet is positioned between the secondary chamber and the reaction chamber to allow passage of the reactive liquid. The inlet is transversely elongate relative to the flow of the reactive liquid. A frangible or removable barrier closes the inlet. A passageway for movement of said infusion or transfusion fluids extends through reaction chamber. The passageway, the reaction chamber and the secondary chamber are all flexible.

Abstract: A device for introducing a liquid (e.g., insulin) into tissue of a subject (e.g., a mammal, such as a human) in need of the liquid. The device includes a cannula having a distal tip. A cannula positioner adjustably (and incrementally) controls a position of the cannula after introduction subcutaneously into a subject. A cannula positioner body allows adjustable support of the cannula and the cannula positioner and may be worn by the subject. The cannula positioner includes a cannula position control member that is adapted to be driven (e.g., longitudinally) to advance or retract the cannula so that a subcutaneous position of the distal tip is changeable among a plurality of locations over a period of at least four days, without removal of the cannula from the subject.

Abstract: The invention relates to a medical hand-held device, in particular an atomizer (1), for dispensing a liquid pharmaceutical preparation from a container with a discharge nozzle for the pharmaceutical preparation and located upstream from the discharge nozzle there is a multiple-stage filter system.

Abstract: A mouthpiece (10) for an inhaler or inhalation device (100) includes an elongated body (12) having a substantially oval opening (14) at a first end and a substantially round opening (18) at a second end opposite from the first end, a plurality of depending arms (24), extending from the elongated body forming at least one air passageway (26) between two depending arms (24), and at least one flexible gripping finger (32) coupled to an inner surface of each depending arm (24), extending inwardly into the medicament delivery passageway of the mouthpiece at or near the substantially round opening (18) at the opposite end. Once coupled with an inhaler or inhalation device, the mouthpiece functions as a “pass through” mouthpiece to improve the consistency of inhaled medicament/drug delivery.

Abstract: The invention relates to a disposable inhaler intended for single use and for substances in powder form which comprises a preferably elongated shape body arranged to, at least partially be inserted in the user's mouth, including one or more air channels arranged in the shape of the body, that a foil is arranged with inlet holes and an outlet holes in connection with the air channels, that a substance in powder form is placed in the air channels, that the foil is arranged to, in the inhaler storage mode, cover the inlet and outlet holes and thus prevent the substance in powder form to fall out of the inhaler air channels, and that tape is removable to be able to use the inhaler and when it is removed exposes the inhaler in-and outlet holes and thus facilitates that the substance in powder form, which is placed in the air channel, can leave the air channel using the airflow that occurs when the user inhales, through the inhaler.

Abstract: A detachable cap for measuring usage of an inhaler includes a hollow receiving portion adapted to removably receive the inhaler. A vent is formed in a roof portion of the cap to allow airflow through the cap to the inhaler. An extension portion is provided for containing electronic components, including an electronic circuit provided in the extension portion, the electronic circuit including a controller coupled to a storage device and a power source. A pressure sensor is provided adjacent to the vent, the pressure sensor communicatively coupled to the controller and adapted to detect an air pressure within the cap. The controller is programmed to calculate an air flow rate through the cap based on the detected air pressure and to store the calculated air flow rate in the storage device.

Abstract: In an embodiment, a respiratory inhaler training device configured to provide stepwise instructions for using the device to a user in a sequence of steps is provided. The respiratory inhaler training device includes a housing defining a channel with an inlet and an outlet, at least one actuation mechanism simulating provision of medicament, at least one fluid flow rate sensor positioned so as to detect a rate of fluid flow through the channel to determine a fluid flow rate, a signal output component for providing an output, a microprocessor and a timekeeping component, a storage medium component associated with the microprocessor comprising a database of instructions pertaining to the sequence and/or timing of steps for using the device stored thereon.

Abstract: An electric hookah for the delivery of medicaments having vaporizable active ingredients, wherein the hookah delivers the vapors at a relatively low temperature, and wherein the hookah is made of parts readily available at local hardware stores is disclosed. The upper tube may retain a heating assembly for heating a medicament so as to produce a vapor. The tubular base may also house a cooling assembly. The electric vaporizer may be adapted so that the vapor flows from the heating assembly, then through at least a portion of a screen assembly and then through the cooling assembly and to an outflow tube for an end user.

Abstract: A patient interface system to treat a respiratory disorder of a patient, the patient interface system comprising: a positioning and stabilising structure including a back portion and a pair of upper straps extending from the back portion; and a patient interface including a patient interface frame and a pair of rigidiser arms each connected to the patient interface frame at a connection point located in a plane substantially parallel to the patient's Frankfort horizontal plane, the pair of rigidiser arms further including a pair of upper attachment points, wherein the pair of upper straps are adapted to be releasably attached to the pair of upper attachment points such that, when donned by the patient, the pair of upper straps are vertically offset relative to the connection points and substantially parallel to the patient's Frankfort horizontal plane, and wherein the patient interface does not include a forehead support.

Abstract: A patient nasal interface is provided that includes a female portion and a first registration feature. The female portion receives a male portion of a generator head. The female portion wraps around and over the male portion when the male portion is inserted into the female portion of the patient nasal interface. The first registration feature is configured for mating with a second registration feature associated with the male portion of the generator head and wherein the mating of the first registration feature with the second registration feature provides a feedback to an operator upon proper insertion of the male portion into the female portion.

Abstract: A headgear system and/or an interface assembly incorporating a headgear system that, in some configurations, is configured to transform from elasticated or “stretchy” behavior to “inelastic” behavior at least in response to normal or expected forces encountered during the intended therapy. In some configurations, upon fitment to the head of a user, the system automatically adjusts toward or to an appropriate size.

Abstract: The invention relates to an arrangement and method for the in-vitro and in-vivo treatment of bronchial tumors.

Abstract: A breathing assistance apparatus user interface is described which presents animated information related to the management of the apparatus. The user interface is provided on a display screen of the apparatus. The animated illustrations can correspond to operational modes, warnings, user instructions, fault conditions, status, menu options, and the like. The animations can include a sequence of images shown in rapid succession which depict moving icons or objects, scrolling text, flashing colors, or any combination of these or the like. The user interface can combine static information along with animations.

Abstract: The present invention provides for eyeglasses used together with contact lenses to deliver light therapy to the wearer. The eyeglass lenses or frames feature an embedded light source in logical and electrical communication with power, sensors, processors, and other components contained within the eyeglasses. The eyeglass lenses or frames project light into complimentary contact lenses which refract, diffract or reflect light into the wearer's eyes.

Abstract: The present invention is directed toward a system and method utilizing synchronized colors, sounds, and aroma therapy. The visual, auditory, and aromatic stimulation is intended to alleviate stress and/or anxiety by relaxing and stimulating the brain, thereby correcting any neurophysical imbalances. Reduction in the levels of stress and/or anxiety is achieved through the use of the auditory, visual, and aromatic sequences which are individually specific and systematic. The system and method is preferably provided in multiple sessions with each session providing both a mechanism for providing treatment as well as assessment, which is used to form the basis for future treatments.

Abstract: A device and method for administering light and acoustic vibrations for therapeutic treatment of one or more users is disclosed. The device has acoustic transducers positioned along a longitudinal center plane and comprises two longitudinal side sections that take an elliptical segment form. The acoustic transducers direct acoustic vibrations upwards, and the device also has light fixtures that direct light downward in the device interior. The components of the device work together to provide auditory, ocular, and dermal stimulation with a substantial reduction in undesirable rattling and echo.

Abstract: A positioning system is disclosed comprising at least three elements, wherein the first element is adapted to be attached to said invasive device, the second element is adapted to be attached to a predefined surface area of a body, and the third element is adapted to be connected to a displaying means. The first element and the second element create a signal, to be received by the third element and which is indicative of the position of the first element within the body. The third element is adapted to receive and visualize said signal emitted from the at least one first and second elements.

Abstract: A catheter has a deflection beam and a single continuous puller wire to effectuate bi-directional deflection. A joint between a catheter body and a deflectable distal section effectively transmits torque from a control handle. The joint includes two open-shaped brackets, each affixed to a respective side of the flat deflection beam to form a closed-shaped hollow body that bridges and circumferentially encircles the beam. Each bracket has through-holes into which thermoplastic material of the catheter body and the deflectable distal section can melt and migrate to form interlocking nodes.

Abstract: A needle guard assembly having a resilient arm extending from a base situated to slide along the shaft of a needle. In one implementation the needle guard has an elongate containment member that rides with the resilient arm and is co-operable with the resilient arm to effectuate a covering of the entire distal tip of the needle upon the needle being retracted into the needle guard.

Abstract: An occlusion sheath having an expandable member is described herein. The occlusion sheath is configured to occlude or limit blood flow to a vessel while providing a central lumen to allow a catheter, such as an imaging catheter and/or an atherectomy catheter, to travel therethrough.

Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.

Abstract: A balloon catheter is described, having a reinforced, co-axial, duel lumen design. At least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element.

Abstract: Described here are systems, devices, and methods for delivery of an implant to a bodily cavity. The implant may include a hub and a plurality of legs, and may be moveable between a low-profile and expanded configuration. The systems may include a crimping device having a crimping member with a plurality of arms. The plurality of arms may engage the plurality of legs of the implant, and may move the legs to move the implant to the low-profile configuration. In some instances a delivery device may aid in crimping and/or delivery of the implant.