Abstract: Described herein are methods, apparatuses, and systems for heart monitoring of a patient. The heart monitoring system can be used to take an electrocardiogram (ECG) using only two electrodes. A handheld device can be used to sequentially measure the electrical signal between different positions on a patient's body. The electrical signals can be processed and analyzed to prepare an ECG for the patient, including a 12-lead ECG.

Abstract: An implantable lead includes a first lead assembly with a distal tip and a medial end, a medial section with a first end and a second end, and a first intermediate assembly disposed between the first lead assembly and the first end of the medial section. The first lead assembly includes a plurality of external contacts and at least one conductive wire disposed in the first lead assembly. The at least one conductive wire extends from at least one external contact towards the medial end of the first lead assembly. The medial section includes a plurality of conductors extending from the first end to the second end. The first intermediate assembly includes a plurality of conductive elements. At least one of the conductive elements is configured and arranged to electrically couple the at least one conductive wire to at least one of the conductors.

Abstract: An implantable medical device has an impedance processor for determining atrial impedance data reflective of the cardiogenic impedance of an atrium of a heart during diastole and/or systole of heart cycle. Ventricular impedance data reflective of the cardiogenic impedance of a ventricle during diastole and/or systole are also determined. The determined impedance data are processed by a representation processor for estimating a diastolic and/or a systolic atrial impedance representation and a diastolic and/or a systolic ventricular impedance representation. A condition processor determines the presence of any heart valve malfunction, such as valve regurgitation and/or stenosis, of at least one heart valve based on the estimated atrial and ventricular impedance representations.

Abstract: A method includes measuring electrical activity at multiple points on a surface of a heart of a patient. User input indicative of a spectral slice selected from a frequency band is received. Respective levels of the electrical activity within the selected spectral slice are calculated. The calculated levels are displayed on a map of the heart.

Abstract: An exemplary embodiment providing one or more improvements includes apparatus and methods for sensing electrical activity in tissue of a person in a manner which is substantially limits or eliminates interference from noise in a surrounding environment.

Abstract: A biomedical sensor for detecting EMG signals may include a non-conducting fixed framework supporting a symmetrical arrangement of four electrode surfaces, configured as two signal detection contacts, each with a respective associated signal reference contact. The mechanical and electrical configuration act together to suppress movement artifact.

Abstract: A biomedical sensor for detecting EMG signals may include a non-conducting fixed framework supporting a symmetrical arrangement of four electrode surfaces, configured as two signal detection contacts, each with a respective associated signal reference contact. The mechanical and electrical configuration act together to suppress movement artifact.

Abstract: Devices, systems, and methods to measure parallel tissue conductance, luminal cross-sectional areas, fluid velocity, and/or determine plaque vulnerability using temperature. In at least one embodiment of a method to obtain parallel tissue conductance, the method comprises the steps of inserting at least part of a detection device into a luminal organ, applying current thereto, obtaining a native temperature measurement, injecting a solution of a known conductivity into the luminal organ, detecting a temperature change indicative of the fluid within the luminal organ, measuring an output conductance, and calculating a parallel tissue conductance based upon the output conductance and the conductivity of the injected solution.

Abstract: Described herein are various technologies pertaining to diagnosing and/or prescribing treatment for osteoporosis. A bone of a patient is subjected to an MRI scan, and the resultant signal is subjected to a likelihood function. The output of the likelihood function are values that are parameters that are employed to ascertain connectivity of trabeculae in the bone of the patient and volumetric trabecular density of the bone.

Abstract: A method for locating a catheter tip within a human body is disclosed. An audio sensor is positioned at a site on the human body. An audio signal is detected by the audio sensor, and transmitted to an audio signal processing unit. The audio signal processing unit determines if the audio signal corresponds to a target location of the catheter tip, and transmits a notification signal to a user notification unit. An infusion of fluid or an audio emitting element can be used to generate the audio signal at the catheter tip.

Abstract: The present invention relates to an implantable apparatus for obtaining urinary control and emptying of the urinary bladder. The apparatus operates with a powered member (100) operating from the outside of the urinary bladder assisted by a support structure to discharge urine from the urinary bladder. A control device (200) controls the operation of the powered member. The control device further comprises a source of energy for operating the powered member and other energy consuming parts of the apparatus and a control assembly.

Abstract: A method of analyzing a plethysmograph signal is disclosed. The method comprises: extracting from the signal a plurality of features, thereby constructing a feature space. The method further comprises employing a path selection procedure to the feature space for determining at least one sequence of respiration frequencies and reconstructing a respiratory signal using the sequence.

Abstract: A measuring device with a measuring tape and a one-piece handle. The handle includes a main body with a fixed reference, an anchor portion with a movable reference and a resilient element. The measuring tape is secured to the anchor portion. The resilient element allows the anchor portion to move with respect to the main body when the measuring tape is under the tension. The resilient element is configured so that the movable reference comes into alignment with the fixed reference when the measuring tape is under proper tension. The fixed reference may also provide a reference from which to take measurements. The resilient element may include a pair of nonlinear segments that straighten under tension. The main body may include a pair of fixed references disposed on opposite sides of the measuring tape, and the anchor portion may include a pair of corresponding movable references.

Abstract: A device for measuring orofacial stiffness in a subject can include: two lip saddle attachment components configured for attachment to the lip saddles of a patients mouth; two elongate members, each being coupled with one of the lip saddle attachment components; a pivot member that couples the two elongate members at a pivot point opposite from the two lip saddle attachment components; an electronic sensor configured to sense the stiffness of the lips by sensing movement of the elongate members with respect to the pivot point, where the electronic sensor is operably coupled to each of the elongate members; and a pressure component configured move with respect to the pivot point so as to provide pressure to and/or receive pressure from the lip saddle attachment components.

Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.

Abstract: Disclosed herein are systems and methods for providing a compressible interconnect for allowing electrical communication between an electronics unit and an analyte sensor in an on-body analyte monitoring device. In other embodiments, systems and methods are provided for reducing the Z-height of an on-body analyte monitoring device by utilizing novel interconnects.

Abstract: A system and method for determining glycemic risks based on an analysis of glucose data includes visualization of hypoglycemia, variability, and hyperglycemia with a control grid, increasing the accuracy of glucose estimates using a combination of CGM and HbA1c, calculating glycemic risk by applying a probability distribution, and tailoring SMBG test schedules based on CGM use/wear.

Abstract: A noninvasive analyzer apparatus and method of use thereof is described using one or a plurality of sample illumination zones coupled to at least one two-dimensional detector array monitoring a plurality of detection zones. Control of illumination times and/or patterns along with selected detection zones yields pathlength resolved groups of spectra. Sectioned pixels and/or zones of the detector are optionally filtered for different light throughput as a function of wavelength. The pathlength resolved groups of spectra are subsequently analyzed to determine an analyte property. Optionally, in the mapping and/or collection phase, incident light is controllably varied in time in terms of any of: sample probe position, incident light solid angle, incident light angle, depth of focus, energy, intensity, and/or detection angle. Optionally, one or more physiological property and/or model property related to a physiological property is used in the analyte property determination.

Abstract: A noninvasive analyzer apparatus and method of use thereof is described using a plurality of sample illumination zones optically coupled to at least two optically stacked two-dimensional optical filter arrays. Sectioned pixels and/or zones of a detector array are optionally filtered for different light throughput and/or are passed through various pathlengths using the stacked two-dimensional optical filter arrays. Resulting pathlength resolved/wavelength controlled groups of spectra are subsequently analyzed to determine an analyte property.

Abstract: A method and an apparatus measure blood oxygenation in a subject. A light source is activated to cause a first emission at a first wavelength and a second emission at a second wavelength. A detector detects a composite signal indicative of an attenuation of the first and second wavelengths by tissue of a patient. The composite signal is demodulated into a first intensity signal and a second intensity signal. Blood oxygenation in the subject is determined from the first and second intensity signals.

Abstract: Methods and systems for determining a physiological parameter in the presence of correlated artifact are provided. One method includes receiving two waveforms corresponding to two different wavelengths of light from a patient. Each of the two waveforms includes a correlated artifact. The method also includes combining the two waveforms to form a plurality of weighted difference waveforms, wherein the plurality of weighted difference waveforms vary from one another by a value of a multiplier. The method further includes identifying one of the weighted difference waveforms from the plurality of weighted difference waveforms using a characteristic of one or more of the plurality of weighted difference waveforms and determining a characteristic of the correlated artifact based at least in part on the identified weighted difference waveform.

Abstract: Embodiments of the present disclosure include a handheld multi-parameter patient monitor capable of determining multiple physiological parameters from the output of a light sensitive detector capable of detecting light attenuated by body tissue. For example, in an embodiment, the monitor is capable of advantageously and accurately displaying one or more of pulse rate, plethysmograph data, perfusion quality, signal confidence, and values of blood constituents in body tissue, including for example, arterial carbon monoxide saturation (“HbCO”), methemoglobin saturation (“HbMet”), total hemoglobin (“Hbt”), arterial oxygen saturation (“SpO2”), fractional arterial oxygen saturation (“SpaO2”), or the like. In an embodiment, the monitor displays a line associated with a patient wellness level.

Abstract: An electrochemical sensor includes a base plate provided with a concave part formed on one of surfaces thereof, a fluid channel formed so that a bottom part of the concave part and the other one of the surfaces of the base plate are communicated with each other, a plurality of electrodes formed on the concave part; a reagent fixed on the electrodes, a cover which covers the concave part, and an air channel which causes the inside and outside of the concave part to be communicated with each other.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes an electrochemical sensor incorporating a silver/silver chloride reference electrode, wherein a capacity of the reference electrode is controlled.

Abstract: A lancet holder includes a holder body having a lancet seat at one end to mount a lancet and receiving the lancet and elastic fixing portions arranged in pairs to face each other on the inner side of the holder body so that the lancet received in the holder body is vertically held, and elastically fixing the lancet.

Abstract: The specification describes a cartridge for insertion into a meter, the interior of the meter comprising a boss having a main body and a protrusion extending from the main body. The cartridge comprises an orientation member provided at one end of the cartridge, the orientation member comprising a recess having a cross-sectional shape corresponding to that of the boss and configured to receive the boss therein, the orientation member further comprising a ramp surrounding at least part of the portion of the recess corresponding to the main body, the portion of the recess which corresponds to the protrusion adjoining the lower end of the ramp via a step.

Abstract: An analyte monitoring system is provided. The system may include a housing (200) and a visual display (206) on the housing (200), the visual display (206) having at lease one visual indicator position next to a corresponding marking (208, 210, 212, 214 and 216) on the housing (200). The system may include a processor (60) driving the visual display (206), wherein the processor (60) runs software that is modifiable to provide a variable user interface on the visual display (206). The system may include a wireless communication to allow applets or programs to be down-loaded by the processor (60).

Abstract: A one repetition maximum (1RM) estimating apparatus includes a potential signal receiving unit configured to receive a potential signal of a muscle from a sensor attached to a user, and a 1RM estimating unit configured to estimate a 1RM of the user based on the potential signal.

Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.

Abstract: A wrinkle detection method comprises the steps of obtaining face data of a subject; setting one or more analytical regions on the obtained face data; producing plural pieces of wrinkle component extracted data by extracting wrinkle components extending in one direction or in plural directions at different angles from each other in an angle range in which wrinkles tend to extend and which is set in advance for the set one or more analytical regions; producing plural pieces of wrinkle component emphasized data corresponding to the pieces of wrinkle component extracted data, respectively, by emphasizing the wrinkle components; producing composite data by combining the pieces of wrinkle component emphasized data; and detecting a wrinkle component having an intensity equal to or greater than a predetermined threshold value from the composite data as a wrinkle of the subject.

Abstract: Systems and related methods are provided for measuring a ketone in the fluid of a patient or other user. The systems include a portable measurement device for analyzing a plurality of fluid samples and for generating a corresponding plurality of ketone measurement results. The systems also include an electronic or communications device, for example, such as a cell phone or smartphone, configured to communicate with the measurement device. The system further includes a software application. The systems and related methods according to one aspect provide reminders, preferably interactive reminders that facilitate user compliance with a weight management or diabetic ketoacidosis (DKA) monitoring or prevention program. The systems and related methods according to another aspect incorporate ketone tags and/or trigger points to improve accuracy of results and to advance user compliance.

Abstract: An optical sensor, having a cover layer, an emitter disposed on a first side of the cover, a detector disposed on the first side of said cover, and a plurality of stacked independent adhesive layers disposed on the same first side of the cover, wherein the top most exposed adhesive layer is attached to a patient's skin. Thus, when the sensor is removed to perform a site check of the tissue location, one of the adhesive layers may also be removed and discarded, exposing a fresh adhesive surface below for re-attachment to a patient's skin. The independent pieces of the adhesive layers can he serially used to extend the useful life of the product.

Abstract: An oximeter probe includes sensor head with a probe face having one or more sensor structures to make measurements, a handle, and an elastic member connected between the handle and the base. A user can hold the handle while measurements are made and the elastic member permits the handle to flex relative to the sensor head with one or more sensor structures.

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one electronic, optical, or electro-optical component positioned within a distal portion of the device and one or more connectors positioned at a distal portion of the device. In some instances, the connectors are flexible coils, such as a ribbon coil, formed of a conductive material. In some particular instances, the conductive coil is embedded within a polymer tubing. Further, in some embodiments the electronic, optical, or electro-optical component is positioned within a flexible element at the distal portion of the device. In some instances the flexible element is a coil. Methods of making and/or assembling such intravascular devices/systems are also provided.

Abstract: The present disclosure relates to systems and methods for collecting patient data via a monitoring system, with reduced power consumption. In one embodiment, the monitoring system is configured to emit pulses of light, and detect the light after passing through patient tissue. The light data is emitted sporadically, and a waveform is reconstructed from the sporadically sampled light data. Physiological parameters from the patient may be calculated from the reconstructed waveform. The sporadic sampling may reduce the power consumption by the monitoring system.

Abstract: An electronic sphygmomanometer having a function to calculate an index value of risk of circulatory system disease from measured blood pressure information includes a CPU, a memory, and a display. The CPU calculates the blood pressure of a person being examined based on pressure changes of an air bladder as measured by a pressure sensor. The memory stores data of the measured blood pressure together with time information of the measurement. The CPU calculates an index value of risk of circulatory system disease of the person being examined based on a difference between a blood pressure value obtained from a measurement and a blood pressure value obtained from a previous measurement and an elapsed time between the measurement and the previous measurement, A display part displays the calculated index value of risk of circulatory system disease of the person being examined together with the measured blood pressure.

Abstract: An intraoral radiation device comprises a biocompatible intraoral receptacle with an X-ray source therein.

Abstract: An apparatus and method for in vivo and ex vivo control, detection and measurement of radiation in therapy, diagnostcs, and related applications accomplished through scintillating fiber detection. One example includes scintillating fibers placed along a delivery guide such as a catheter for measuring applied radiation levels during radiotherapy treatments, sensing locations of a radiation source, or providing feedback of sensed radiation. Another option is to place the fibers into a positioning device such as a balloon, or otherwise in the field of the radiation delivery. The scintillating fibers provide light output levels correlating to the levels of radiation striking the fibers and comparative measurement between fibers can be used for more extensive dose mapping. Adjustments to a radiation treatment may be made as needed based on actual and measured applied dosages as determined by the fiber detectors. Characteristics of a radiation source may also be measured using scintillating materials.

Abstract: A hand-held direct digital image sensor device includes a connection handle having a grip portion, a bite portion, and a carrier portion provided with at least one male coupling unit; a soft protective cover provided with at least one female coupling unit for engaging with the male coupling unit; and a direct digital image sensor received in a receiving cavity defined in the protective cover. Through engagement of the male and female coupling units with one another, the soft protective cover and accordingly the direct digital image sensor received therein can be connected to an end of the connection handle and be extended into a patient's oral cavity without bringing too much discomfort to the patient. The used protective cover is discarded or disinfected to meet sanitary requirements in medical treatment.

Abstract: An imaging system (500) includes an annular shaped rotating gantry (504) having an aperture (501) and configured to support at least a radiation source, wherein the rotating gantry rotates about a rotation axis (508) around an examination region, and wherein the rotation axis is located within the aperture in a center region (508) of the examination region. The imaging system further includes a stationary gantry (502), configured to rotatably support the rotating gantry. The stationary gantry includes a gantry base (516), an annular shaped tilt frame (518) that rotatably supports the rotating gantry, and a tilt system (520) affixed to and between the gantry base and the tilt frame, wherein the tilt system defines a tilt axis (522) of the stationary gantry, the tilt axis is located between the gantry base and the rotation axis, and the tilt frame tilts about the tilt axis.

Abstract: According to one embodiment, a cooler includes a casing, a radiator unit which is installed in a circulation path, where a coolant is circulated, and is configured to externally discharge heat of the coolant, and a fan unit housed in the casing to generate an air flow passing through the radiator unit. A windward side of the radiator unit is exposed to an outer side of the casing.

Abstract: A method for obtaining a digital chest x-ray image of a patient, executed at least in part by a computer system, acquires a standard dose radiographic image and a reduced dose radiographic image, wherein the standard dose radiographic image and reduced dose radiographic images are obtained at peak kilovoltage values that differ by at least 10 kVp. A bone-enhanced image is formed by combining data from the standard dose radiographic image and reduced dose radiographic images and bone structure is segmented from the bone-enhanced image. A processed image is formed by suppressing bone contrast from the standard dose radiographic image according to the segmented bone structure. The processed image is displayed, stored, or transmitted.

Abstract: A method establishes a spatial position of a part of an x-ray ruler imaged in at least one x-ray image. The X-ray ruler is attached to an alignment of an object to be x-rayed. The X-ray ruler has at least a first part and a second part each having x-ray markers, and the first and second parts are connected to each other by a connection element. A spatial configuration of the x-ray markers is determined on a basis of images of the x-markers in an x-ray image or x-ray images.

Abstract: The invention relates generally to the measurement and dimensional analysis of an object and, more particularly, to the correction of distortion in volumetric data of the object using dimensional data of the object. In one embodiment, the invention provides a method of analyzing an object, the method comprising: acquiring volumetric data of an object using an X-ray computed tomography (CT) imaging system; acquiring dimensional data of the object using a vision-based system; determining whether the volumetric data include a distortion; and in the case that the volumetric data are determined to include a distortion, correcting the distortion in the volumetric data using the dimensional data.

Abstract: In part, the invention relates to processing, tracking and registering angiography images and elements in such images relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT). Registration between such imaging modalities is facilitated by tracking of a marker of the intravascular imaging probe performed on the angiography images obtained during a pullback. Further, detecting and tracking vessel centerlines is used to perform a continuous registration between OCT and angiography images in one embodiment.

Abstract: A source controller unit for controlling an x-ray source is provided with a detection signal interface for receiving detection signals from detective pixels of an electronic cassette or an integrated value of the detection signals only, or an interface for receiving a radiation stopping signal only. The source controller unit receives other radiation signals than the radiation stopping signal, such as a radiation admitting signal, through a radiation signal interface. The source controller unit uses the detection signals, the integrated value thereof, or the radiation stopping signal as exposure control signals for stopping radiation from the x-ray source. Since the exposure control signals are received on the specific interface therefor, the source controller unit does not need signal sorting operation nor receive different kinds of signals at the same time, improving the speed of radiation stopping procedure.

Abstract: A scanning method and device are provided. The method includes: determining values for a first scanning dosage and a second scanning dosage used in a scanning process based on a trigger condition which varies regularly and attenuation fluctuations of an object to be scanned, wherein the first scanning dosage is higher than the second scanning dosage, and at least one of the first scanning dosage and the second scanning dosage has an inconstant value; and scanning a target position with the determined values. In the present disclosure, a scanning dosage may be reduced and different image noises may be kept consistent.

Abstract: There is provided a calibration apparatus used for a photon counting type of radiation detector. In this apparatus, a radiation condition of a radiation is set such that particles of the radiation (X-rays) which are incident on a plurality of detection modules are piled up over each other at a probability which is equal to or less than a predetermined value. Under the setting of this radiation condition, detection sensitivities for the radiation are made uniform among the plurality of detection modules. Using this uniformed result, the detection sensitivities for the radiation are further made uniform every channel of each of the pixels formed by circuit groups including the plurality of detection modules, discrimination circuits and data calculation circuits and every discrimination circuit in each channel.

Abstract: A mechanical scanning device is composed of an oscillating beam onto which a transducer is mounted, part of which is flexible such that the beam will oscillate at a frequency between 8 and 15 Hz when mechanically energized. To sustain oscillations, energy is supplied by means of two electromagnetic coils acting on two permanent magnets mounted on either side of the beam. In order to improve the linear performance of the probe, feedback control was employed. A position sensor along with supporting electronics was designed to provide control signal for the feedback system.

Abstract: An intravascular ultrasound (IVUS) imaging system and catheter with an intuitive interface for rapid operator interaction using acquired medical images. In an embodiment, an IVUS imaging system and catheter are used to acquire a sequence of a specific area of interest in the human anatomy, for example, tomographic images of a coronary artery. The IVUS imaging system displays at least one tomographic image of the area of interest. The IVUS imaging system generates and displays at least one longitudinal image, wherein the longitudinal image represents a cut-plane of the sequence of tomographic images. The IVUS imaging system further includes a touch screen, wherein the system recognizes touch movements to facilitate searching the sequence of images. Touch movements in a longitudinal direction may pan the longitudinal image in the longitudinal direction. Touch movements in the transverse direction may rotate the cut-plane of the longitudinal image.