Abstract: A kit for making a glenoid prosthesis is provided. The kit includes an articulating member having an articulation side and an opposing second side opposing the articulating side, in which the opposing second side includes a locking mechanism. The kit also includes a plurality of bases. Each of the plurality of bases has an articulating member facing side and a glenoid attachment side, in which each of the plurality of glenoid attachment sides includes at least one glenoid attachment member extending outwardly and sized and shaped to extend into a patient's glenoid. The glenoid attachment member of one of the plurality of bases differs from the glenoid attachment member of at least one other of the plurality of bases, and in which each of the plurality of bases includes a locking mechanism sized and shaped to lock each of the plurality of bases to the articulating member.

Abstract: The present application is generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. The vertebral implants and implant trials may be used in conjunction with corpectomy procedures. One type of vertebral implant is a corpectomy device having a polyaxial endplate assembly. The polyaxial endplate assembly includes an articulatable plate member that is capable of angulation. The articulatable plate member can be fixed in place by, for example, using a clamping assembly to fix the articulatable plate member.

Abstract: Methods for treating an annulus fibrosis having a defect include inserting a flexible device into the defect. The flexible device is advanced distally beyond an outer layer of the annulus fibrosus. The flexible device is then expanded such that a width of the flexible device is larger than the defect, where the flexible device prevents escape of nucleus pulposus through the defect. The flexible device may have at least two appendages made from a shape-memory metal. Alternatively, the flexible device may have a U-shaped structure that includes a central portion and two legs. The flexible device may also be anchored to the annulus fibrosis and/or the vertebrae.

Abstract: Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Abstract: Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Abstract: An implant device is provided for implantation within an intervertebral space between adjacent vertebrae comprising an implant body, a rotatable portion and a piercing portion configured to pierce the adjacent vertebra.

Abstract: Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

Abstract: Medical instrumentation is provided, in particular for implanting a hip joint stem, which includes a rasping instrument having a rasp stem defining a longitudinal direction. The rasp stem has at least two depth stops arranged or formed thereon. An implantation set is also provided which includes such a rasping instrument.

Abstract: A system and method for allowing any surgeon, including those surgeons who perform a fewer number of a replacement procedure as compared to a more experienced surgeon who performs a greater number of procedures, to provide an improved likelihood of a favorable outcome approaching, if not exceeding, a likelihood of a favorable outcome as performed by a very experienced surgeon with the replacement procedure.

Abstract: Systems, devices, and methods are provided for aligning acetabular implants. A patient-matched acetabular alignment tool is used to orient tools and implants intraoperatively. The patient-matched acetabular alignment tool includes a mounting member and leg members which are configured based on the particular patient's anatomic landmark sites (e.g., acetabular bony landmarks). The leg members are attached to the mounting member and configured to connect with a respective anatomic landmark site to achieve a desired implant angle and axis. For example, the leg members may form a tripod support base through which an acetabular shell may be inserted into the patient's acetabulum at desired angles of version and inclination. In some embodiments, the leg members may be retractable and expandable with respect to the mounting member, thereby providing a tool with reduced profile for inserting the device in the patient's soft tissue.

Abstract: A modular acetabular impactor and reamer system including a main body extending between a proximal handle end and a distal end. The system also includes a transmission rotatingly extending within the main body. The transmission has an accessory mount. The system also has at least one of an impactor handle and a reamer handle removably coupled to the main body proximal handle end. The impactor handle has a drive shaft to drive rotation relative to the impactor handle. The reamer handle has a drive mount to drive rotation relative to the reamer handle. The system also has at least one of an impactor cup and a reamer module removably coupled to the main body distal end. The transmission and the at least one of the impactor cup and the reamer module correspondingly rotate relative to the main body.

Abstract: Joint fixation systems and methods, enabling: drilling one or more major bores in a joint; drilling one or more minor bores in the joint, wherein the one or more minor bores are disposed about a periphery of and partially overlap the major bore(s); and disposing an implant in the major bore(s) and the one or more minor bores, wherein a cross-sectional shape of the implant substantially conforms to a collective cross-sectional shape of the major bore(s) and the one or more minor bores. Prior to drilling the major bore(s) or the one or more minor bores, a portal tube is disposed adjacent to the joint, thereby providing access to and stabilizing the joint. A drill guide tube is disposed concentrically within the portal tube, and a drill guide is disposed concentrically within the drill guide tube. Subsequent to drilling the major bore(s) and the one or more minor bores, an implant guide tube is disposed concentrically within the portal tube.

Abstract: Devices and methods provide for measuring applied pressure on an article, such as a patella construct during a surgical procedure. Embodiments include a clamp having an upper frame arm, a lower frame arm and a clamp assembly, and further include a clamp with a knob assembly and a pressure monitor assembly. Differently sized bushing adapters can be interchangeably employed with a clamp stem to adapt to the relative sizes of objects being clamped.

Abstract: Orthopedic implant sizing instruments, systems, and methods for use during arthroplasty procedures, for example, radial head arthroplasty procedures, are provided. The sizing instruments include at least one sizer head having at least one visualization window or slot provided therethrough for allowing a user to visualize associated surgical structures or surfaces to ensure proper joint reduction. The orthopedic implant sizing instruments, systems, and/or related methods can utilize sizer heads and/or windows having a plurality of different sizes and/or shapes.

Abstract: A medical force measuring system is provided for measuring a force effective between two prosthesis parts that are connected to one another in articulated manner in a joint prosthesis which includes a ball joint or a partial component thereof. The force measuring system includes a measuring instrument which has a sample joint element with a sample joint surface. The sample joint element is formed in correspondence with a first joint element that forms a part of the ball joint and has a joint surface which is formed in correspondence with the sample joint surface and is moveable into engagement therewith for forming a sample ball joint. The measuring instrument also includes at least one of a measuring device and an indicating device which cooperates with the sample joint element for measuring and/or indicating a force (or a partial component thereof) effective on the sample joint surface.

Abstract: A joint replacement balancing system which provides real-time feedback to a surgeon during a joint replacement surgery to assist the surgeon to balance a joint replacement. The joint replacement balancing system includes a non-transitory processor-readable medium storing code representing instructions to cause a processor to receive a signal from a joint balancing apparatus, determine if the joint replacement is out of balance, determine a corrective course of action to bring the joint into balance and generate and display to the surgeon during the joint replacement surgery a recommended corrective course of action to complete the joint replacement surgery.

Abstract: A prosthetic device comprises a plurality of polymer units attached to one or more leaf springs. The polymer units are spaced apart and define spaces between the units such that there is no contact between any two polymer units at maximum deflection of the one or more leaf springs. The polymer units may be impermeable to water and the spaces may facilitate free flow of liquids out of the device. The plurality of polymer units may comprise a heel piece and a toe piece. One or both of the heel piece and the toe piece may extend beneath the one or more leaf springs such that the one or more leaf springs do not contact the ground when the device is used for ambulatory movement. The toe piece may extend further down than the heel piece and may extend beneath the one or more leaf springs such that extension of the toe piece provides increased flexing of the one or more leaf springs.

Abstract: A programmable prosthetic foot includes a heel member simulating a heel portion of a human foot. The heel member has an elongated heel member shaft extending in a vertical direction. The foot also includes a forefoot member simulating a forefoot portion of a human foot. The forefoot member has an elongated forefoot member shaft extending in the vertical direction. A sensor on the foot detects compressive force on the heel member shaft and/or forefoot member shaft during a step. An actuator on the foot imparts vertical translation to the heel member shaft and/or forefoot member shaft. An electronic controller in operable communication with the actuator includes program instructions for operating the actuator by imparting the vertical translation to the heel member shaft and/or forefoot member shaft as a function of the compressive force detected by the sensor.

Abstract: A fitting system for electronically representing both the static fitting and the dynamic movement of artificial prostheses is provided. The fitting system embodies a method of disposing a plurality of force sensing resistors along a prosthetic interface, wherein each force sensing resistor has an output element; noting a spatial relationship and a sequential relationship between each of the plurality of force sensing resistors; and providing a micro controller electrically interconnected between each output element and a display device, wherein the micro controller is configured to electrically represent a force output of each output element on the display device so that each force output is identified with the associated spatial relationship and the associated sequential relationship relative to the plurality of force sensing resistors.

Abstract: An absorbable endoluminal stent and method for preparing the same are provided in the present invention. The absorbable endoluminal stent comprises a stent body, a plurality of through holes formed in the stent body, and bioabsorbable polymeric materials filled in the through holes. When the stent is implanted into the blood vessels, damages on stent caused during crimping and expansion processes are reduced. Radical supporting force duration of stent is improved and mechanical properties of stent after implantation are guaranteed by compositing the materials in the through holes and materials of the stent body.

Abstract: An endoprosthesis includes an expandable tubular framework having a first end, a second end, and a lumen extending therethrough along a longitudinal axis. The expandable tubular framework includes a plurality of interconnected struts. The interconnected struts include a radially outward face which includes a plurality of anti-migration grooves defining anti-migration teeth formed therebetween. The anti-migration teeth are configured to engage tissue to resist migration of the endoprosthesis within a body lumen.

Abstract: Medical devices and method for making and using the same are disclosed. An example medical device may include implantable medical device for use along the biliary and/or pancreatic tract. The implantable medical device may include a tubular member having a first end configured to be disposed within the duodenum of a patient and a second end configured to be disposed adjacent to a pancreatic duct and/or bile duct. The tubular member may have a body including one or more wire filaments that are woven together. The tubular member may also have an outer surface with a longitudinal channel formed therein.

Abstract: An implantable stent includes a stent retrieval member for repositioning or retrieval of the stent after it has been implanted into a bodily lumen. The stent includes a distensible tubular stent having a tubular structure having a tubular wall defined by an interior surface and an exterior surface and having opposed open ends; and a stent retrieval member comprising an elongate member comprising a generally circular perimetric base and a shaped projection having first and second spaced apart members extending acutely or perpendicularly from the base and connected by an apical portion. Force exerted on the shaped projection causes contraction or expansion of the circular base. The circular base is securably attached to one of the open ends of the stent, and the shaped projection extends longitudinally beyond this open end of the stent.

Abstract: A braided stent having an integral retrieval and/or repositioning loop includes a plurality of wires having first and second ends interbraided in a braided pattern to form a tubular stent having opposed atraumatic first and second open ends with each open end having a circumference; wherein said first and second wires ends are disposed at said second stent open end and said wires are looped at said second stent open end so that none of the first or second wires ends are exposed at the circumference of second stent open end; wherein at least of two of said wires are formed into a repositioning and/or retrieval loop having an elongated portion circumferentially disposed at said first opposed open end; and wherein said reposition and/or retrieval loop comprises two sections which run adjacent to each other prior to crossing to permit grabbing of both sections simultaneously by a practitioner.

Abstract: The present invention relates to an endoluminal device for implantation in a body lumen, such as a pancreatic duct. The device is provided with a distal end region having greater flexibility than that of a medial region of the device.

Abstract: The present invention relates to a nanoparticle composition which is prepared by a process which is characterized by dissolving a poorly water-soluble compound or the like under a high temperature and a high pressure, and milling a suspension or the like containing a uniform crystal obtained by cooling the obtained solution.

Abstract: An introducer for an endoluminal prosthesis and a methods for delivering a prosthesis within a body vessel are described. The introducer comprises pusher catheter having a lumen extending therethrough, the lumen being in communication with an opening formed in the sidewall of the pusher. A sheath is disposed over the pusher catheter and also has an opening formed in its sidewall. The sheath is longitudinally movable relative to the pusher catheter between a prosthesis delivery position and a prosthesis deployment position. When the sheath is in the deployment position, the opening formed in the sidewall of the pusher catheter is at least partially longitudinally aligned with the opening formed in the sidewall of the sheath. A wire may extend though the opening in the sheath, the opening in the pusher, through the lumen of the pusher and through a fenestration in a prosthesis to cannulate a branch vessel.

Abstract: An implant release mechanism for releasing, for example, a stent (60) is provided with three restraining wires (62) which pass in the space between a wire guide catheter (24) and a pusher sheath or dilator (30) and are arranged substantially equi-angularly threrearound. Each restraining wire (62) holds both the proximal and distal ends of the stent (60), in this case each holding a proportion of the ends of the stent (60). When the restraining wires (62) are pulled they will first unwrap from the proximal end of the stent (60) and will then release the distal end of the stent (60) so as to allow the stent to become fully deployed within the lumen of the patient. The use of common release wires improves deployment of implants and reduces the number and volume of components in the device, thereby allowing it to occupy a smaller volume.

Abstract: Stent delivery system having a contracted delivery configuration and an expanded deployed configuration is provided. The stent delivery system includes a stent having a plurality of expandable elements and a plurality of interstices disposed between adjacent expandable elements, and a delivery catheter having an inflatable balloon including creases extending non-uniformly within the interstices of the stent in the contracted delivery configuration. Each crease defines a maximum radial height within a corresponding interstice, and the maximum radial heights of the creases vary. A method for stenting at a target site within a patient's vessel including providing a stent delivery system is also provided.

Abstract: The present embodiments provide system and methods for deploying an endoluminal prosthesis. In one example, the system comprises a sheath, and a stent-graft disposed within the sheath in a delivery state. A pusher having proximal and distal sections is disposed at least partially within the sheath in the delivery state. An orientation marker is disposed on the pusher. The orientation marker extends less than 360 degrees around a circumference of the pusher.

Abstract: A pre-loaded stent graft delivery device having a guide wire catheter and a handle including a multi-port manifold with access ports, where an access sheath extends from each access port. A sheath is disposed coaxially around the guide wire catheter and includes two splits that enable the retraction of the sheath while the access sheaths are disposed within the respective access port of the manifold.

Abstract: A gastric device for a stomach having a pyloric valve comprising a biodegradable delivery structure disposable within the stomach configured to erode upon exposure to gastric fluid. A first volume filling agent retained by the biodegradable delivery structure and is permeable to water and/or gastric fluids. A second volume filling agent retained by the first volume filling agent, wherein the second volume filling agent is a hydrogel that expands in contact with the water and/or gastric fluids thereby expanding the first volume filling agent from a first displacement to a second displacement larger than the first displacement, and wherein the first volume filling agent does not pass through the pyloric valve in the normal digestive process.

Abstract: In certain aspects, the present invention is a purely mechanical stance control orthosis, or stated differently, a weight acceptance control orthosis, as it stabilizes the impaired knee joint during the first 40% of the gait cycles termed as the weight acceptance phase. The device employs a tri-stable fixture to lock/unlock a friction-based latch to provide two levels of stiffness. The device is locked during the weight acceptance phase to stabilize the impaired knee joint for an orthotic application or avoid collapse for a prosthetic application, and is unlocked during the rest to allow free rotation. The device includes an engagement fixture, a locking mechanism, a chassis, and a frame. The engagement fixture controls the locking mechanism to lock and unlock movement in the chassis and frame in response to a wearer's weight load and is capable of locking at any angle.

Abstract: An orthotic, in particular a knee orthotic, comprises a pair of rail arms, which in each case have a pivoting first rail arm section and a second rail arm section that can be fastened to a patient's body. The second rail arm section of at least one rail arm is held on the first rail arm section in a slope—adjustable manner and in a movable manner in the longitudinal direction of the rail arm and is forcibly controlled such that a pivoting of the rail arms in the flexion or extension direction is coupled both with an adjustment in the medial or lateral inclination of the second rail arm section and with a change in length of the rail arm.

Abstract: An underwear for chiropractic is disclosed. The underwear includes: a main body configured to wrap an upper part of a human body; an opening and closing unit including a zipper disposed at a front of the main body; a fastening unit including a plurality of holes disposed at a rear of the main body and a rope and a third fixing unit; a plurality of supports configured to support a spine by being fixed at the main body; and a pelvis supporter disposed at a lower part of the main body and made of an elastic mesh member, and including an opening formed between two of wearing holes for legs of a user to be inserted. According to an exemplary embodiment, the underwear has effects of keeping a correct posture and correcting the spine, by firmly supporting the core muscles.

Abstract: The invention relates to a disposable mouth guard, conformable to individual mouth structures, characterized in that it comprises compacted fibrous material comprising: end tongues suitable for improving the positioning of the device, wherein said end tongues are shaped to be wrapped around a user's gums in order to prevent the movement of the guard against the teeth.

Abstract: An appliance for use in a method of reducing facial aging and/or oral parafunctional activity e.g. bruxism, comprises two parts, the parts intended in use to contact the posterior teeth on respective opposite sides of either the upper or lower jaw, each part comprising a composite structure comprising: iii) a first layer (2) formed of a durable, resilient, elastomeric material comprising a cured thermoset rubber and which in use contacts the occlusal biting surfaces of the posterior teeth; and iv) a second layer (3) formed of a durable, non-deformable material having a softening point over 100° C. and which in use provides a bite plate; wherein the second layer of each part, that has a substantially planar first surface, is provided with a protrusion (5), formed of durable, non-deformable material having a softening point over 100° C.

Abstract: An insert comprising a non-toxic, acidic component having a pH of under 4.0 is fitted into the tip of a condom, where ejaculation during sexual intercourse will release a sufficient amount of the acidic component to immobilize sperm cells and kill Human Immunodeficiency Virus (HIV).

Abstract: A portable thermal therapy apparatus is for executing an operating method capable of recording the thermal therapy procedure. The operating method for a portable thermal therapy apparatus includes receiving an operating command, the operating command at least having an operating parameter, executing an operating procedure according to the operating command, the operating procedure at least including an operating mode, and recording the operating mode into an operating log message.

Abstract: The present invention relates to a method and system for producing and delivering sterile, airless, and highly loaded ice slurry for inducing therapeutic hypothermia. The method is capable of producing and delivering ice slurry in a patient to induce hypothermia through internal and external cooling methods such as subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods. The method is capable of producing and delivering saline ice slurry or other phase-change slurries compatible with human tissues. Ice slurry is made by crushing, smoothing, and mixing ice slush in an airtight and self-collapsible liquid container, followed by being pumped out through flexible tubing and injection port into a patient body without air. The novel method and system are simple, and easy to use, which facilitate long term storage, immediately ready to use, and airless delivery.

Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting or positioning a thermal device in proximity to the targeted tissue. A number of exemplary thermal devices are disclosed, including bone anchors, inserts for use with bone anchors, K-wires, bone anchor extensions or towers, cross-connectors, spinous process plates, spinal rods, pedicle markers, bone taps, drill bits, bone plugs, bone plates, clamps, interbody or disc implants, thermal pads, and tubing loops. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner.

Abstract: An optical surgical probe includes a cylindrical cannula; a light guide partially within the cannula to receive a light beam from a light source through a proximal end, to guide the light beam to a distal end of the light guide, and to emit the light beam through the distal end of the light guide; a multi-spot generator at a distal end of the cannula that includes an optical element with a proximal surface to receive the emitted light beam, and a focusing lens, positioned inside the optical element to focus the received light beam into a focused beam, wherein the optical element has a faceted distal surface to split the focused beam into multiple distally emitted beam-components when the optical surgical probe is operated in a fluid with an index of refraction of 1.30-1.40, and to confine the focused beam in the optical surgical probe when the optical surgical probe is operated in air.

Abstract: An optical surgical probe can include a cylindrical cannula; a light guide, partially within the cannula, configured to receive a light beam from a light source through a proximal end, and to emit the light beam through a distal end; and a multi-spot generator at a distal end of the cannula, the multi-spot generator including a glass optical element with a faceted proximal surface, configured to receive the light beam from the light guide, and to split the light beam into beam-components; and a ball lens inside the glass optical element, configured to focus the beam-components to multiple spots in an image plane.

Abstract: A surgical laser system includes a laser engine, configured to generate a laser beam of laser pulses; a proximal optics and a distal optics, together configured to direct the laser beam to a target region, and to scan the laser beam in the target region through a scanning-point sequence; and an aberration sensor, configured to sense aberration by an aberration layer; a compensation controller, coupled to the aberration sensor, configured to generate compensation-point-dependent phase compensation control signals based on the sensed aberration; and a spatial phase compensator, positioned between the proximal optics and the distal optics, at a conjugate aberration surface, conjugate to the aberration layer, and coupled to the compensation controller, configured to receive the compensation-point-dependent phase compensation control signals, and to alter a phase of the laser beam in a compensation-point-dependent manner to compensate the sensed aberration.

Abstract: A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye, the patient interface using liquid used as a transmission medium for the laser. During a laser procedure sensors monitor the level of liquid within the patient interface and send a signal to control electronics if the level drops below a threshold value. The sensor may be mounted on the inside of the patient interface, within a fluid chamber. Alternatively, a gas flow meter may be added to a suction circuit for the patient interface that detects abnormal suction levels indicating low fluid level.

Abstract: In corneal crosslinking by applying a photoactivated crosslinking facilitator such as riboflavin to the cornea and irradiating the cornea with light, the cornea is contacted with a liquid (33) containing a source of oxygen during irradiation. The liquid transfers oxygen to the cornea to facilitate crosslinking.

Abstract: Iontophoresis, a minimally-invasive methodology that uses a weak electric current to enhance penetration of ionized molecules into tissues, was found to be an effective technique for the intraocular delivery of large bioactive molecules, specifically lutein.

Abstract: Devices, systems, and methods for visualizing moving tissue with strobed light are provided. A surgical system includes a surgical device configured to operate on anatomy at a first frequency such that the anatomy moves at the first frequency when the surgical device is in contact therewith; and a light source configured to provide pulses of light at a second frequency to illuminate the moving anatomy; wherein the second frequency is different than the first frequency. A method of treating an ophthalmic condition includes operating a surgical device at a first frequency such that anatomy moves at the first frequency when the surgical device is contacted therewith; and controlling a light source to provide pulses of light at a second frequency to illuminate the moving anatomy; wherein the second frequency is different than the first frequency. An ophthalmic surgical system includes a cutting probe, a strobed light source, and a computing device.

Abstract: A surgical handpiece has at least two working tips and at least two ultrasonic drivers. Each of the ultrasonic drivers creates longitudinal mechanical vibration. At least two connecting pieces connect each of the ultrasonic drivers to one separate working tip so that the mechanical vibration of one driver is applied to one tip independent of the application of the mechanical vibration of the other driver applied to the other tip. A control system independently controls the amplitude of the mechanical vibration from each of the ultrasonic drivers. In one embodiment the drivers are both in a single housing, and optionally a lever is provided on the handpiece to operate in conjunction with one or both of the tips. In another embodiment, the drivers are in separate housings that can be pivoted with respect to each other.

Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.