Abstract: An ophthalmic irrigator-aspirator has a handpiece with aspiration and irrigation openings through its distal end. A tip component connects to the handpiece and has an aspiration cannula. A flexible sleeve has an annular hub for watertight connection to the handpiece or a base portion of the tip. The sleeve has an intermediate portion that forms a channel for an irrigation fluid along the exterior of the cannula to an irrigation port in the sleeve. The distal end portion of the sleeve is sized for a watertight connection over the distal portion of the cannula. Such distal end portion of the sleeve has an aspiration port in communication with the cannula aspiration port. The sleeve proximate, intermediate, and distal portions are integral with each other and are formed of a resilient material that allows the sleeve to be tightly fitted on the handpiece or tip base portion and the cannula.

Abstract: A method and apparatus to operate a surgical instrument in response to a thermal condition being detected that warrants curtailment of further operation. When the thermal condition is reached, command signals are generated that cause a needle of the surgical instrument to either have its vibrational speed slowed, have its vibrational movement stopped, or have it withdrawn from its relative position. The detection is of infrared radiation wavelengths and is carried out with either a thermal imaging device of a thermal recognition device. A corresponding temperature of the detected infrared radiation wavelengths is compared to a critical temperature to determine whether the thermal condition has been reached.

Abstract: A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.

Abstract: Systems and methods for treating a patient having an ear canal and a target tissue function by positioning a fluid or a gel in the ear canal, the fluid or the gel comprising a therapeutic agent; retaining the fluid or the gel with a support structure, the support structure supporting an electrode and a battery; and applying the therapeutic agent from the fluid or the gel to the target tissue by energizing the electrode with an iontophoresis potential from the battery.

Abstract: A tubular body is configured to be disposed around and to apply compression to an extremity. The tubular body includes a treatment area having a first filament and a second filament. Both the first filament and the second filament are disposed to engage the surface of the extremity. The first filament includes AgNP in a concentration effective to promote healing of a wound on the surface of the extremity. The second filament includes a metal having a composition that forms a galvanic couple with silver. The first filament and the second filament are arranged in the tubular body such that the AgNP and metal form galvanic couples across at least a portion of the treatment area when in the presence of a fluid in the wound of the extremity that produce an electric current in an amount effective to further promote healing of the wound.

Abstract: An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. microfiltration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing mate rials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.

Abstract: A device for the protection of skin lesions of various kinds, in particular lesions following biopsy interventions, comprising: a first sheet having a central opening; a spacing element on the first sheet, made of a non-rigid material soaked with substances having bacteriostatic, bactericidal, germicidal or fungicidal activity, and having a central opening of smaller size than the central opening in the first sheet, and the center of which is essentially coincident with the center of the opening in the first sheet, so that part of the spacing element comes into contact with the skin in an area surrounding the lesion; and a second sheet, made with a material having micro-porosity preferably lower than 0.5 ?m, placed over the spacing element so as to close the top of the central opening in said spacing element and to form, when the device is in contact with the skin, a closed chamber.

Abstract: A breastfeeding assistance device configured to be shaped into a variety of configurations, or forms. The device being self-sustainable in any selected configuration including a configuration that compresses a breast to assist with breastfeeding while allowing at least one hand free.

Abstract: A device and method to avert anal fecal leakage is disclosed that possess at least two means for the prevention of anal leakage or hemostatic application. The device is inserted internally and is used inside of the rectal cavity for absorption along with a sealing member placed externally against the anus which is designed as a secondary means for the prevention of leakage. An embodiment of the device includes a third sealing means to prevent leakage into the anal canal. The device is constructed to be flexible with a minimum of intrusiveness for the user during use. The device is constructed for one person insertion and removal unless patient or user is incapacitated. Due to its design, the device is capable for use over a wide range of human and certain animal applications.

Abstract: The invention relates to a method for increasing the skin or wound compatibility of a hygiene or wound care product, which has a cellulose nonwoven fabric and which is present in the form of a web, or of a precursor product of said hygiene or wound care product. The product is stretched and deviated in at least one direction in such manner that the cohesion of fibers or flakes of the cellulose nonwoven fabric is weakened, reduced, disrupted, or broken down at least in some sections.

Abstract: Apparatus and methods are provided to minimize waste and improve quality and production in web processing operations. A first non-elastomeric layer is bonded with an elastomeric layer, and to a second non-elastomeric layer. The apparatus and methods provide defect detection in the elastomeric layer and triggers an unthreading/rethreading sequence. Web defect detection may be provided by way of at least one visual inspection station. If defects are detected in the elastic layer, the resulting products may be culled.

Abstract: A disposable absorbent article includes a chassis and a liquid-absorbent structure. The chassis has an inner sheet lying on a skin-facing side and an outer sheet lying on a garment-facing side. The outer sheet has a first outer sheet and a second outer sheet lying inside the first outer sheet. The second outer sheet is formed on its outer surface with a display area extending in a longitudinal direction. The liquid-absorbent structure is formed with a central void and lateral voids in which core material for a core is not present. The display area can be visually recognized from the garment-facing side through the first outer sheet and from the skin-facing side also through the central void of the liquid-absorbent structure.

Abstract: A sanitary product for use by women for the absorption of menstrual fluid has a plug and a pad joined by a sheath. The plug is substantially cylindrical so that it fits comfortably in a vaginal cavity. The pad remains outside the vaginal cavity, but has an absorbent layer on an inward side proximal to the plug and a liquid impermeable layer on an outward side. The sheath includes a tube of absorbent material for drawing excess menstrual fluid from the plug to the pad and has a layer of liquid impermeable material on its inside surface. It extends from an outward end of the plug, proximal to the pad, both to and through the pad. In use, a wearer can insert a finger into the sheath from the outward side of the pad to assist with insertion of the plug into the vaginal cavity.

Abstract: A disposable absorbent article has a central body that includes an absorbent core, a front longitudinal edge, and a rear longitudinal edge opposite the front longitudinal edge. The disposable absorbent article also has a pair of elasticized side panels that extend longitudinally adjacent opposite lateral sides of the central body. Each side panel has a front longitudinal edge and a rear longitudinal edge opposite the front longitudinal edge, and a front or rear fastening element positioned adjacent the front or rear edge. The front edge of the side panel is positioned closer to the front waist portion than the rear edge. The fastening element is constructed for fastening the front and rear waist portions of the central body when the disposable absorbent article is worn by a user.

Abstract: The present invention addresses the problem of providing a novel absorbent article that prevents excessive compression of an absorbent body caused by deformation of the absorbent article, and rewetting associated with said compression. In order to solve such a problem, a sanitary napkin (1) is provided with a liquid-permeable top sheet (2), a liquid-impermeable back sheet (3), and an absorbent body (4) disposed between the top sheet (2) and the back sheet (3), wherein: an extensible area (21) having an extensible bellows-like section (210), and a flexible area (22) surrounding the extensible area (21) are formed in a waste supply area (20) of the top sheet (2).

Abstract: An absorbent article includes a fluid pervious top sheet, a fluid impervious bottom sheet, and an absorbent core positioned therebetween. The absorbent core includes a plurality of superabsorbent sections defining a channel therebetween.

Abstract: An absorbent article package is individually packaged by folding a packaging sheet and an absorbent article in a state where the absorbent article is arranged on the packaging sheet. In a state where the individually-packaged absorbent article is opened, in the packaging sheet and the absorbent article, a first folding line based on which the absorbent article and the packaging sheet are folded towards the topsheet side, and a second folding line based on which the absorbent article and the packaging sheet are folded towards the backsheet side are formed adjacent to each other in the longitudinal direction.

Abstract: Reusable outer covers for wearable absorbent articles.

Abstract: A dual drive wheelchair comprising a frame with a seat, a rear driving wheel set including a cross axle and a vertical rod, wherein the cross axle connects two rear wheels, a supporting structure including a support and an axial tube, wherein the support is connected to the frame and a front driving wheel set; and the axial tube fits around the vertical rod, and further comprising a first steering member of the first turning structure connected to the support and a second steering member of the first turning structure; wherein the second steering member is fixed to the vertical rod and a control structure including a pair of backrest canes fixed to the first steering member enabling a user or a caregiver to operate the control structure of the dual drive wheelchair.

Abstract: A method for varying the width of a health care bed includes providing a health care bed having a floor engaging base frame and a bed frame, the bed frame including at least two bed sections hingedly connected to each other and each having a central frame portion and left and right wing sections, the wing sections having at least a retracted position and an extended position relative to the central frame portion, and wherein the central frame portion defines, for each wing section, at least inner and outer registration holes and the wing sections each define at least one wing hole that aligns with one of the at least inner and outer registration holes when the wing sections are in the respective retracted and extended positions, and for each wing section, at least one locking mechanism having at least one rocker bar with opposing inner and outer ends, at least one spring and at least one locking button for releasably locking the wing sections in the retracted and extended positions; unlocking the at least one

Abstract: A bed rail for engagement between a mattress and a box spring and having a base support and a guard frame, with guard frame having a pivot that pivots and slides in the base support. The base support includes a first seat that seats the pivot and a second seat that seats a biased piece sliding axially on a first support member of the guard frame. The first support member extends from a plastic piece that forms a junction from which a second support member and the pivot extend and that nestles up to the second seat.

Abstract: A sanitary disposable urine device is provided. The device includes an inner ring and outer ring each having a top surface and opposing bottom surface. The outer ring is substantially concentric with the inner ring and may be offset. At least one of the top surfaces of the inner and outer rings conforms to a body contour of a user's perineum. The device further includes a hand holder coupled to the bottom surface of the inner ring, the hand holder having an opening configured to match to the inner ring. The device also includes a fluid containing bag having an open end attached to the hand holder such that fluid flows through the inner ring and the opening of the hand holder into the fluid containing bag during usage. The device also includes an inner bag inside the fluid containing bag for containing an absorbent material and an outer sealable bag to secure the device after use.

Abstract: A two-piece casket containment system is provided that consist of an upper cover and lower base, both of which are made from a pliable, lightweight waterproof material, and both of which may be cinched around the casket through use of a drawstring assembly.

Abstract: A crutch includes: a handgrip (2) extending along a first axis (AA1); a forearm support (3), provided with a stem (3b) which extends along a second axis (AA2) and is connected to a rear end (2a) of the handgrip (2); a support pole (4), extending along a third axis (AA3) and connected to a front end (2a) of the handgrip (2); and adjusting members (5), configured to adjust an angular position of at least one of the support pole (4) and the forearm support (3) with respect to the handgrip (2).

Abstract: A care support apparatus includes a lateral pair of leg links held by a main body. The leg links include first links provided with first wheels at respective one ends of the first links, and second links provided with second wheels at respective one ends of the second links and rotatably coupled to the first links. The second links are rotated to allow the first wheels to approach or leave the second wheels, respectively, to change the height of a main body from a ground surface to support a care receiver.

Abstract: A compression sleeve includes a wicking layer secured to bladder material defining an inflatable bladder along a seamline. Fibers of the wicking layer extend through the seamline to allow fluid wicked by the wicking layer from the wearer's skin to evaporate to the atmosphere.

Abstract: Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein. In some aspects, the system includes a chest compression sensor providing movement information during a plurality of manual chest compressions performed by a rescuer on a chest of a patient; a release sensor providing information as to whether the rescuer's hands are in contact with the release sensor during manual chest compressions or not in contact with the release sensor between manual chest compressions; a computing unit; and an audio and/or visual display providing feedback received from the computing unit to the rescuer regarding chest compression rate, chest compression depth and whether the rescuer's hands are not in contact with the release sensor between manual chest compressions.

Abstract: A frangible electrical circuit sheet for a dosage form package includes a first plurality of electrically conductive trace subnetworks interconnected with one another to form a network of electrically conductive traces and disposed on the sheet. The sheet further includes a second plurality of circuit elements connected to the network of electrically conductive traces such that each circuit element is associated with one of the subnetworks. At least some of the circuit elements have element values that differ from one another.

Abstract: An outer sleeve includes first and second opposed side panels edges, hinge panels interconnecting the first and second side panels such that at least one chamber is defined between the first and second side panels, at least one of the hinge panels being hingedly connected to at least one of the first and second side panels along one of the opposed side edges of the at least one side panel, and at least one inner panel positioned at least in part inside the at least one chamber. The at least one inner panel includes a slide card locking mechanism for releasably locking at least one slide card in a locked position within the at least one chamber. The at least one side panel includes a release button positioned proximate the slide card locking mechanism of the at least one inner panel. The at least one inner panel is hingedly connected to one of the end edges of the at least one panel.

Abstract: The integrated puncture needle adapter is equipped with: a puncture needle; a needle hub; a tubular fixing part for fixing the needle hub; a tubular puncture needle accommodating part provided on a distal side of the tubular fixing part and having therein an accommodating space for accommodating the puncture needle; a second connecting part provided on a distal side of the puncture needle accommodating part; and a separable part which is formed between the tubular fixing part and the puncture needle accommodating part. A part on the distal side of the separable part is separable from a part on the proximal side of the separable part. The puncture needle is exposed when separated.

Abstract: A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

Abstract: The invention relates to blood substitute compositions, and methods of use thereof. Described herein are compositions in which hemoglobin is maintained substantially in the reduced form of hemoglobin as opposed to the oxidized methemoglobin form through inclusion of an oxido-reductase enzyme and reducing agent within a vesicle with the hemoglobin. The vesicles additionally can comprise a dismutase, a catalase, and an electron acceptor, each of which contribute to either the maintenance of hemoglobin in the active oxygen carrying state or provide a benefit not achieved with free hemoglobin.

Abstract: Apparatus and methods relating to a metered pill dispensing system are disclosed herein. A preloaded cartridge having multiple compartments containing dispensable contents, such as pills, is inserted into a cassette. The cassette has an actuatable member, such as a film or a belt, wrapped around it. The actuatable member has apertures through which the contents of the preloaded cartridge may pass. The actuatable member may be controlled to meter the dispensing of the contents.

Abstract: A medication container comprises a body portion and a grid coupled to the body portion. The grid and the tray each comprise a corresponding number of wells configured to contain medication. The tray is configured to be inserted into and removed from the body portion, above the grid. The tray may be configured to be connected to and disconnected from the grid, when the tray is inserted into the body portion. The wells of the grid may be configured to be manually loaded with medication by a user and the wells of the tray may be configured to be received by the user loaded with medication in accordance with a medication regimen. The first wells may be integral with the grid and the second wells may be integral with the tray.

Abstract: The present invention provides a tablet-inspecting device in which the control unit gives, to the continuous drug packet-driving unit, operation instructions to move the continuous drug packet from an upstream side to a downstream side of the conveyor path, and reciprocating operation instructions to alternately move the continuous drug packet to the upstream side and the downstream side of the conveyor path, the control unit gives, to the rod control unit, rod unit pressing operation instructions to press the rod unit against the side portion of the drug packet, and when the control unit gives the reciprocating operation instructions, the rod unit pressing operation instructions has been given, it is possible to enhance determining precision of the number of tablets or the kinds of tablet, and to stably inspect drugs.

Abstract: Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

Abstract: There is disclosed a nipple (10) suitable for a soother, feeding bottle or drinking vessel. The nipple (10) has a teat portion (12), an areola portion (14) and a base portion (16). The nipple (10) has an interior wall (15) and a plurality of paths (20), prefereably at least partly recessed, in the interior wall (15). Each path (20) has a first end (25) located in the teat portion (12) and a second end (26) located in the areola portion (14).

Abstract: The present invention relates to use of whey protein micelles as a cosmetic agent or abrasive agents, and in particular to the use of such micelles in cosmetic compositions as well as to a method for obtaining such compositions.

Abstract: The present invention generally relates to compositions and methods for transdermal delivery, treatment of skin, and improving the appearance of skin. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.

Abstract: This invention relates to compositions containing a retinoid and use of the compositions for treating skin conditions.

Abstract: A method for simultaneously moisturizing and/or blurring the appearance of skin defects, or reducing pore size, or treating skin with a multi-benefit composition.

Abstract: A pharmaceutical composition comprising a lipid component; an amphiphilic emulsifier; and a polar liquid carrier. The lipid component and the amphiphilic emulsifier form free-moving lipid-carrying micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure.

Abstract: Methods, systems, devices, and medicaments are provided for locally administering to a pelvic-area organ or tissue structure in a patient at least one drug continuously or continually over a treatment period of 24 hours or more in an amount effective to achieve a therapeutic effect in another organ or tissue structure by means of shared or convergent pelvic afferent pathways. The methods systems, devices, and medicaments can be used in the treatment of IC/BPS, chronic pelvic pain, vulvodynia, orchialgia, urethral syndrome, dysparenia, chronic prostatitis, chronic pelvic pain, levator ani syndrome, irritative bowel syndrome, or a combination thereof. The drug may include anesthetic agents, analgesic agents, antispasmodic agents, antimuscarinic agents, and combinations thereof. The drug may be released from a drug delivery device or a sustained release composition deployed inside the bladder.

Abstract: The present invention relates to ophthalmic preparations in the form of eyedrops based on BDNF (Brain-Derived Neurotrophic Factor). Said preparations can be administered topically to the intact eye surface, and are useful in the prevention and treatment of neurodegenerative disorders of the retina, optic nerve, lateral geniculate body and visual cortex, in order to prevent reduction of visual capacity and restore the normal visual function.

Abstract: Described herein are liquid rapamycin formulations. Described herein are methods of treating or preventing diseases or conditions, such as choroidal neovascularization, wet AMD and dry AMD, and preventing transition of dry AMD to wet AMD, using the liquid rapamycin formulations described herein.

Abstract: The present invention relates to a controlled-release oral dosage form for administration of oxycodone once a day and a method of preparing a controlled-release oral dosage form for administration of oxycodone once a day.

Abstract: The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention.

Abstract: A chewing gum with a liquid-fill composition and a surrounding gum region, with one or both containing active ingredients, such as herbal, medicinal and/or mineral elements or combinations thereof, present in an amount of at least about 0.05 mg.

Abstract: The invention provides stable, spray-dried, particle formulations containing rapamycin, or pharmaceutically acceptable salts of rapamycin, which are useful for pulmonary administration to the respiratory tract of a patient for the treatment of disease.

Abstract: A liposome containing a regulatory cell ligand such as ?-galactosyl ceramide or ?-galactosyl ceramide is employed as the active ingredient of a drug for preventing or treating immune diseases etc.