Patents Issued in July 12, 2016
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Patent number: 9388079Abstract: A wall repair compound useful for filling and repairing cracks, holes, and other imperfections in a wall surface includes a conventional filler material, a conventional binder material, and a dust reducing additive which reduces the quantity of airborne dust particles generated when sanding the hardened joint compound. Airborne dust reducing additives include oils, surfactants, solvents, waxes, and other petroleum derivatives. The additive can be added to conventional ready-mixed joint compounds and to setting type joint compounds. A method of reducing the quantity of airborne dust generated when sanding a fully hardened joint compound includes mixing a sufficient quantity of the dust reducing additive with the joint compound prior to when the joint compound has been applied to the wall.Type: GrantFiled: May 8, 2012Date of Patent: July 12, 2016Assignee: 3M Innovative Properties CompanyInventor: Nathaniel P. Langford
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Patent number: 9388080Abstract: A permanent filter for a medical sterilization container is provided. The permanent filter is made from a ceramic. The ceramic is made from globular substrate grains. A medical sterilization container is also provided, in particular for receiving and storing objects to be sterilized, having a container bottom part and a container top part for closing the container bottom part in a closed position of the sterilization container. At least one of the container bottom part and the container top part have a gas exchange orifice, which is closed with a permanent filter. The permanent filter is made from a ceramic and the ceramic is made from globular substrate grains. In addition, a method is provided for producing a permanent filter for a medical sterilization container. The permanent filter is produced from a ceramic material by sintering. Globular substrate grains are used as the ceramic material.Type: GrantFiled: October 31, 2014Date of Patent: July 12, 2016Assignee: Aesculap AGInventors: Dieter Weisshaupt, Thomas Weik, Stefan Schuster, John Gray-Dreizler, Wolfgang Burger
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Patent number: 9388081Abstract: The present invention relates to refractory articles in general having improved surface properties. The objective of the invention is to propose an improvement of the refractory articles comprised of a fused silica matrix which will overcome the some of the defects while keeping the excellent known properties of the fused silica matrix. This objective is reached when a sintered ceramic phase is present in the porosity of at least a portion of at least a surface of the matrix. The present invention also relates to a process for producing such an article.Type: GrantFiled: May 14, 2007Date of Patent: July 12, 2016Assignee: VESUVIUS CRUCIBLE COMPANYInventors: Nathalie Niveau, Gilbert Rancoule
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Patent number: 9388082Abstract: The present invention aims at providing a porous molded product comprising magnesium and aluminum which is satisfactory in both of a specific surface area and mechanical properties, can be suitably used as filters, drying agents, adsorbents, purifying agents, deodorants, carriers for catalysts, etc., includes a large amount of micropores, and has a large specific surface area and a high strength, as well as a process for producing the porous molded product. The porous molded product of the present invention comprises at least magnesium and aluminum, and having a magnesium content of 10 to 50% by weight in terms of a magnesium atom, an aluminum content of 5 to 35% by weight in terms of an aluminum atom, a pore volume of 0.01 to 0.5 cm3/g, an average pore diameter of not more than 300 ? and an average collapse strength of not less than 3 kg, and can be produced by molding hydrotalcite comprising at least magnesium and aluminum and then calcining the resulting molded product at a temperature of 500 to 1500° C.Type: GrantFiled: December 25, 2008Date of Patent: July 12, 2016Assignee: TODA KOGYO CORPORATIONInventors: Shinji Takahashi, Naoya Kobayashi
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Patent number: 9388083Abstract: Disclosed are a silicon carbide sintered body and a sliding component using the same, and a protective body which, even when fine cracks are generated due to thermal shock or mechanical impact over prolonged use, are capable of inhibiting development of the cracks. The silicon carbide sintered body contains silicon carbide grains as a major component and has a relative density of 95% or more. On an observation surface of the silicon carbide sintered body, coarse silicon carbide grains 1b having a surface area of 170 ?m2 or more occupy 6 area % or more and 15 area % or less. The silicon carbide sintered body has excellent mechanical properties such as strength and rigidity. Even when fine cracks are generated due to thermal shock or mechanical impact, coarse silicon carbide grains 1b are capable of inhibiting development of the cracks.Type: GrantFiled: February 24, 2011Date of Patent: July 12, 2016Assignee: KYOCERA CorporationInventors: Mami Iida, Mieko Yashima, Yuusaku Ishimine, Kazuhiro Ishikawa
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Patent number: 9388084Abstract: Sintered product exhibiting a relative density of greater than 97% and composed of: more than 92% by weight of silicon carbide, between 0.5% and 8% by weight of an amorphous secondary phase comprising the elements O, Si and one or two elements chosen from Al and Y, less than 2% of other elements, present in said product in the form of an additional phase or of unavoidable impurities, in which the silicon carbide is present in the form of crystalline grains and in which said secondary phase is amorphous and located essentially at the boundaries of the silicon carbide grains.Type: GrantFiled: April 15, 2013Date of Patent: July 12, 2016Assignees: SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Gilles Rossiquet, Eric Jorge
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Patent number: 9388085Abstract: A titanium compound-containing core-shell powder includes a plurality of core-shell particles, each of which includes a core body and a shell layer encapsulating said core body. The core body is electrically conductive. The shell layer includes a crystal that is selected from titanate oxides having a perovskite structure and titanate oxides having a spinel structure. The core body and the shell layer are chemically bonded to each other.Type: GrantFiled: August 29, 2014Date of Patent: July 12, 2016Assignee: YAGEO CORPORATIONInventor: Masayuki Fujimoto
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Patent number: 9388086Abstract: In accordance with the present embodiment, a method for making an optical ceramic comprises depositing a plurality of thin layers of powder. The powder comprises a first optical material powder having a first dopant level, and a second optical material powder. The first and second optical material powders are deposited for each layer based on the first dopant level and according to data associated with a three-dimensional (3D) compositional profile design of an optical ceramic. The method further comprises binding the first and second optical material powders of each thin layer to each other and each thin layer with an adjacent layer such that a green state optical ceramic is produced based on the 3D compositional profile design. The method further comprises densifying the green state optical ceramic to obtain the optical ceramic.Type: GrantFiled: March 4, 2011Date of Patent: July 12, 2016Assignee: RAYTHEON COMPANYInventors: Jiyun C. Imholt, Richard L. Gentilman, Thomas M. Hartnett
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Patent number: 9388087Abstract: Liquid anti-oxidants made by mixing specific chemical compositions disclosed herein, followed by thorough stirring so that a homogeneous blend of colloidal-like solutions are obtained. Such liquid anti-oxidants are applied to the surface of the carbon-carbon composite that is needed to be protected against oxidation by brushing, dipping, spraying, or other painting techniques, and allowed sufficient time for the anti-oxidants to penetrate into the subsurface region of the composite and to let dry in a dry atmosphere. The coated carbon/carbon composites can be heat treated (or charred) at a temperature of about approximately 650 to 950° C. for a time period of about approximately one to seven hours. The above painting/heat treating processes can be repeated one to three or more times in order to obtain sufficient anti-oxidant char on or below the surface to a certain depth of the composite.Type: GrantFiled: March 14, 2014Date of Patent: July 12, 2016Assignee: BOARD OF TRUSTEES, SOUTHERN ILLINOIS UNIVERSITYInventor: Jarlen Don
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Patent number: 9388088Abstract: The present invention relates to a process wherein organic material derived from plant and animal material is processed to recover nutritional elements. In particular, there is provided a process for releasing nutritional elements from plant and animal material comprising the steps of treating the material with one or more enzymes to digest said material under appropriate conditions and separating the resulting liquid hydrolysate from the undigested material.Type: GrantFiled: July 21, 2015Date of Patent: July 12, 2016Assignee: REDF-ORGANIC RECOVERY, LLCInventors: Jeffrey W. Young, Lewis A. Spencer
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Patent number: 9388089Abstract: An encapsulated particle includes a core particle and a polyurethane layer. The polyurethane layer is disposed about the core particle and includes the reaction product of an isocyanate and a polyol component. The polyurethane layer is formed in the presence of a silicone surfactant. The polyol component includes a first polyol having a nominal functionality of at least 2.5 and a hydroxyl number of from 20 to 300 mg KOH/g. A method of encapsulating the core particle includes the steps of providing the core particle, the silicone surfactant, the isocyanate, and the polyol component. The method also includes the steps of mixing the isocyanate and the polyol component and encapsulating the core particle with the polyurethane layer.Type: GrantFiled: May 20, 2013Date of Patent: July 12, 2016Assignee: BASF SEInventors: Raymond Neff, Alexander Gershanovich, Donald Mente
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Patent number: 9388090Abstract: A catalyst free method of igniting an ionic liquid is provided. The method can include mixing a liquid hypergol with a HAN-based ionic liquid to ignite the HAN-based ionic liquid in the absence of a catalyst. The HAN-based ionic liquid and the liquid hypergol can be injected into a combustion chamber. The HAN-based ionic liquid and the liquid hypergol can impinge upon a stagnation plate positioned at top portion of the combustion chamber.Type: GrantFiled: October 11, 2012Date of Patent: July 12, 2016Assignee: Physical Sciences, Inc.Inventors: Prakash B. Joshi, Lawrence G. Piper, David B. Oakes, Justin L. Sabourin, Adam J. Hicks, B. David Green, Anait Tsinberg, Allan Dokhan
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Patent number: 9388091Abstract: A catalyst for methanation of carbon dioxide. The catalyst is formed by mixing ash from a biomass power plant with a nickel compound and calcining the resulting mixture. The catalyst formed by calcination includes between 2 and 20 wt. % of nickel.Type: GrantFiled: April 1, 2014Date of Patent: July 12, 2016Assignee: WUHAN KAIDI ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.Inventors: Zhilong Wang, Yanfeng Zhang, Yilong Chen, Yongjie Xue, Leiming Tao, Zhixiang Luo, Xingcai Zheng
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Performance of Ga- and Zn-exchanged ZSM-5 zeolite catalyst for conversion of oxygenates to aromatics
Patent number: 9388092Abstract: The present invention relates to a process for producing aromatic hydrocarbons comprising contacting a feedstream comprising an oxygenate with a catalyst composition comprising a medium pore-size aluminosilicate zeolite further comprising gallium and one or more elements selected from Group 12 of the Periodic Table. The process of the present invention is preferably performed in absence of any feed diluents.Type: GrantFiled: December 17, 2012Date of Patent: July 12, 2016Assignee: SAUDI BASIC INDUSTRIES CORPORATIONInventor: Kartick Chandra Mondal -
Patent number: 9388093Abstract: Systems for ionic liquid catalyzed hydrocarbon conversion comprise a reactor vessel, a mixing device in fluid communication with the reactor vessel, and at least one circulation loop in fluid communication with the reactor vessel and the mixing device. The mixing device may comprise an upper venturi, at least one feed injection component, and a lower venturi. Such systems may be used for ionic liquid catalyzed alkylation reactions. Processes for ionic liquid catalyzed hydrocarbon conversion are also disclosed.Type: GrantFiled: July 3, 2014Date of Patent: July 12, 2016Assignee: Chevron U.S.A. Inc.Inventors: Huping Luo, Moinuddin Ahmed, Krishniah Parimi, Bong Kyu Chang, Michael John Girgis, Donald Henry Mohr, Hye Kyung Cho Timken
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Patent number: 9388094Abstract: Disclosed is a hydrocarbon conversion process in which an alkane component is catalytically converted in the presence of an oxygen or oxidizing component (i.e., oxidant). The hydrocarbon conversion process can be an oxidative coupling reaction, which refers to the catalytic conversion of alkane in the presence of oxidant to produce an olefin product, i.e., a composition containing C2+ olefin. Reverse-flow reactors can be used to carry out the oxidative coupling reaction.Type: GrantFiled: August 26, 2014Date of Patent: July 12, 2016Assignee: ExxonMobil Chemical Patents Inc.Inventor: Paul F. Keusenkothen
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Patent number: 9388095Abstract: The present invention relates to a multi staged cracking and stripping process that can be used in a fluidized-bed catalytic cracking process or FCC (fluidized catalytic cracking) process for maximizing the production of olefins, that is to say of C3 and C4 olefins, in particular propylene and distillates. One subject of the present invention is therefore a multi-staged process for cracking and stripping a fluidized mixture of hydrocarbons and of coked catalyst particles, integrated into a conventional fluidized-bed catalytic cracking process comprising at least one cracking step and one stripping step after separation of the particles of coked catalyst from the cracked effluent during the disengaging/stripping step, characterized in that it comprises at least two steps of cracking at least one hydrocarbonaceous fluid over the separated coked catalyst particles followed by at least two steps of stripping these particles, each cracking step preceding a stripping step.Type: GrantFiled: October 11, 2011Date of Patent: July 12, 2016Assignee: TOTAL RAFFINAGE MARKETINGInventors: Patrick Leroy, Marc Bories, Michaël Echard
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Patent number: 9388096Abstract: A producing method of monocyclic aromatic hydrocarbons in which reaction products including monocyclic aromatic hydrocarbons are produced by bringing an oil feedstock and an aromatic production catalyst into contact with each other, the oil feedstock having a 10 volume % distillation temperature of more than or equal to 140° C. and a 90 volume % distillation temperature of less than or equal to 380° C., the method including the steps of: introducing the oil feedstock into a fluidized-bed reaction apparatus housing the aromatic production catalyst; bringing the oil feedstock and the aromatic production catalyst into contact with each other in the fluidized-bed reaction apparatus; and introducing steam into the fluidized-bed reaction apparatus based on the introducing amount of the oil feedstock per hour.Type: GrantFiled: May 24, 2012Date of Patent: July 12, 2016Assignees: JX Nippon Oil & Energy Corporation, CHIYODA CORPORATIONInventors: Shinichiro Yanagawa, Yasuyuki Iwasa, Susumu Yasui, Yoshishige Sugi, Atsushi Fukui, Atsuro Nagumo, Osamu Hirohata
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Patent number: 9388097Abstract: A method for treating a substrate prior to a metathesis reaction includes treating the substrate with a first agent configured to mitigate potentially adverse effects of one or more contaminants in the substrate on a catalyst used to catalyze the metathesis reaction. The treating reduces a level of the one or more contaminants by an amount sufficient to enable the metathesis reaction to proceed at a substrate-to-catalyst molar ratio of at least about 7,500 to 1. Methods for metathesizing substrates are described.Type: GrantFiled: March 13, 2014Date of Patent: July 12, 2016Assignee: Elevance Renewable Sciences, Inc.Inventors: Keith M. Wampler, Steven A. Cohen, Georg E. Frater, Levente Ondi, Jeno Varga
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Patent number: 9388098Abstract: Methods and compositions are provided for refining natural oils and for producing high-weight esters, high-weight acids, and/or high-weight derivatives thereof, wherein the compositions are made by cross-metathesizing low-weight unsaturated esters or low-weight unsaturated acids having hydrocarbon chain lengths less than or equal to C24 with an olefin feedstock, thereby forming a metathesized product composition including high-weight esters or high-weight acids having hydrocarbon chain lengths greater than C18, wherein at least a portion of the hydrocarbon chain lengths in the metathesized product are larger than the hydrocarbon chain lengths in the starting feedstock.Type: GrantFiled: April 3, 2015Date of Patent: July 12, 2016Assignee: Elevance Renewable Sciences, Inc.Inventors: Bruce Firth, Brian M. Pease, Alexander D. Ilseman, Garrett Zopp, Timothy A. Murphy, Robin Weitkamp, Michelle Morie-Bebel
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Patent number: 9388099Abstract: This invention provides a process for producing 2,3,3,3-tetrafluoropropene, the process comprising: (1) a first reaction step of reacting hydrogen fluoride with at least one chlorine-containing compound selected from the group consisting of a chloropropane represented by Formula (1): CClX2CHClCH2Cl, wherein each X is the same or different and is CI or F, a chloropropene represented by Formula (2): CClY2CCl?CH2, wherein each Y is the same or different and is CI or F, and a chloropropene represented by Formula (3): CZ2?CClCH2Cl, wherein each Z is the same or different and is CI or F in a gas phase in the absence of a catalyst while heating; and (2) a second reaction step of reacting hydrogen fluoride with a reaction product obtained in the first reaction step in a gas phase in the presence of a fluorination catalyst while heating. According to the process of this invention, 2,3,3,3-tetrafluoropropene (HFO-1234yf) can be obtained with high selectivity, and catalyst deterioration can be suppressed.Type: GrantFiled: April 24, 2015Date of Patent: July 12, 2016Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Kazuhiro Takahashi, Yuzo Komatsu, Akinori Ueda
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Patent number: 9388100Abstract: Methods and systems for purifying feedstock-to-ethanol fermentation products are disclosed. The methods include the use of a solvent in the form of a supercritical fluid or liquid gas such as supercritical CO2 or liquid CO2 to dry fermentation beer solids, and/or to extract oil, ethanol, or ethanol and oil from fermentation beer or mixtures derived therefrom. Systems include a separations reactor having a first portion defined by walls that are impermeable to fermentation beer liquids joined to a second portion defined by walls that are impermeable to fermentation beer liquids by a third portion defined by walls that are permeable to fermentation beer liquids and impermeable to fermentation beer solids.Type: GrantFiled: August 14, 2015Date of Patent: July 12, 2016Assignee: POET RESEARCH, INC.Inventor: Steven G Redford
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Patent number: 9388101Abstract: A polymer compound comprising a constitutional unit represented by the formula (1): in the formula, Ar1 represents an aromatic hydrocarbon group or an aromatic heterocyclic group, E represents a group obtained by removing one hydrogen atom in a compound represented by the formula (2): in the formula, R1 to R10 represents a hydrogen atom, an alkyl group, an aryl group, a monovalent aromatic heterocyclic group or a group represented by —O—RA, RA represents an alkyl group, an aryl group or a monovalent aromatic heterocyclic group, and aa is an integer of 1 or more.Type: GrantFiled: February 24, 2011Date of Patent: July 12, 2016Assignee: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Tomoyasu Yoshida, Hidenori Hanaoka, Shota Moriwaki
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Patent number: 9388102Abstract: In a process for producing phenol, cyclohexylbenzene is contacted with an oxygen-containing compound in the presence of an oxidation catalyst comprising a cyclic imide under oxidation conditions effective to produce a product comprising cyclohexylbenzene hydroperoxide and unreacted cyclic imide catalyst. Without removing all the unreacted cyclic imide catalyst, at least a portion of the product is contacted with an acidic molecular sieve under conditions effective to adsorb at least a portion of the unreacted cyclic imide and to convert at least part of the cyclohexylbenzene hydroperoxide in the product portion into phenol and cyclohexanone.Type: GrantFiled: December 15, 2011Date of Patent: July 12, 2016Assignee: ExxonMobil Chemical Patents Inc.Inventors: Kun Wang, Roberto Garcia, Jihad M. Dakka, Edmund J. Mozeleski
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Patent number: 9388103Abstract: In a process for producing phenol, a feed comprising cyclohexylbenzene hydroperoxide is contacted with a cleavage catalyst comprising an acidic ionic liquid under cleavage conditions effective to cleave at least a portion of said cyclohexylbenzene hydroperoxide and produce a cleavage product stream comprising phenol and cyclohexanone.Type: GrantFiled: August 9, 2012Date of Patent: July 12, 2016Assignee: ExxonMobil Chemical Patents Inc.Inventors: Kun Wang, Roberto Garcia, Francisco M. Benitez
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Patent number: 9388104Abstract: Provided are methods of preparing a monodisperse oligo (ethylene glycol) reagent composition.Type: GrantFiled: April 8, 2014Date of Patent: July 12, 2016Assignee: Nektar TherapeuticsInventors: Michael D. Bentley, Tacey X. Viegas, Richard R. Goodin, Lin Cheng, Xuan Zhao
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Patent number: 9388105Abstract: A liquid phase hydrogenolysis of acetal compounds, such as cyclic acetals and cyclic ketals, is disclosed. The acetal compounds are fed to a reaction zone and reacted in the presence of a noble metal catalyst supported on a carbon or silica support to make hydroxy mono-ether compounds in high selectivity, without the necessity of using acidic co-catalysts such as phosphorus containing acids or stabilizers such as hydroquinone.Type: GrantFiled: June 24, 2011Date of Patent: July 12, 2016Assignee: Eastman Chemical CompanyInventors: Damon Ray Billodeaux, Thomas James Devon, Jonathan Michael Penney, Daniel Latham Terrill, Robert Thomas Hembre, Jerome Leonard Stavinoha, Jr.
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Patent number: 9388106Abstract: A surfactant composition selected from the group consisting of: (R1O)CH2—CH[(OCH2CH2)1-20OH]—CH2(OR2) and mixtures thereof; wherein at least one of R1 and R2 are secondary alkyl groups including from 3 to 9 Carbon atoms; an aqueous coating composition including an aqueous polymeric dispersion; and certain other compositions including the surfactant composition are provided. Also provided is a method for forming a coating.Type: GrantFiled: September 16, 2013Date of Patent: July 12, 2016Assignee: Dow Global Technologies LLCInventors: Irina V. Graf, Arkady L. Krasovskiy
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Patent number: 9388107Abstract: The present invention provides a process for continuously preparing a mixture of cyclohexanone and cyclohexanol comprising, a) hydrogenating phenol with gaseous hydrogen, in the presence of platinum or palladium, in a hydrogenation reactor, to produce a hydrogenation product stream comprising cyclohexanone, cyclohexanol, phenol and hydrogen; b) cooling the hydrogenation product stream to a temperature such that the fraction of phenol by mass in a first gas phase is lower than the fraction of phenol by mass in a first liquid phase; c) separating the first gas phase from the first liquid phase; d) returning at least part of the first gas phase to the hydrogenation reactor; e) heating the first liquid phase; f) purifying the first liquid phase by distillation; characterized in that heat is transferred from the hydrogenation product stream in step b) to another part of the process by means of in-process heat exchange; a mixture of cyclohexanone and cyclohexanol obtained by the process; and a chemical plant suitabType: GrantFiled: June 27, 2013Date of Patent: July 12, 2016Assignee: CAP III B.V.Inventors: Wilhelmus Rudolf Maria Martens, Robert Jan De Korte, Iris Verschuren, Corinne Daguenet, Johan Thomas Tinge, Roeland Wilhelmus Theodorus Maria Brands
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Patent number: 9388108Abstract: A compound that includes vanillin and ethylvanillin, and a method for making same are described. The compound described can be obtained by the co-crystallization of vanillin and ethylvanillin. Methods of using the compound in numerous applicable fields, particularly in human and animal food are also described.Type: GrantFiled: October 8, 2009Date of Patent: July 12, 2016Assignee: Rhodia OperationsInventor: Jean-Claude Le-Thiesse
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Patent number: 9388109Abstract: With respect to reduced coenzyme Q10, there has been no report about the presence of crystal polymorphism, and it has been considered that a conventionally obtained crystal form is only one form. The present invention relates to a reduced coenzyme Q10 crystal having an endothermic peak indicating melting at 54±2° C. during temperature rise at a rate of 5° C./min by differential scanning calorimetry (DSC), and/or to a reduced coenzyme Q10 crystal showing characteristic peaks at diffraction angles (2?±0.2°) of 11.5°, 18.2°, 19.3°, 22.3°, 23.0° and 33.3° by powder X-ray (Cu—K?) diffraction. The crystal form is a novel reduced coenzyme Q10 crystal which has a higher melting point and a lower solubility in a solvent, and is more excellent in stability than the conventionally known reduced coenzyme Q10 crystal.Type: GrantFiled: June 21, 2012Date of Patent: July 12, 2016Assignee: KANEKA CORPORATIONInventors: Hideo Kawachi, Shiro Kitamura, Yasuyoshi Ueda
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Patent number: 9388110Abstract: Systems and methods for liquid-phase oxidation of an aromatic feedstock containing at least one oxidizable aromatic compound may incorporate an oxidation reactor, a separation apparatus in fluidic communication with the oxidation reactor, a solids treatment unit, and a product recovery unit in fluidic communication with the separation apparatus. The oxidation reactor may conduct liquid-phase oxidation of the oxidizable aromatic compound in the aromatic feedstock in the presence of a manganate salt to form a slurry containing liquid product and solid manganese dioxide. The separation apparatus may accept the slurry from the oxidation reactor and separate the liquid component from the solid component. The solids treatment unit accepts the solid component from the separation apparatus, treats the solid component with a basic liquid to oxidize the manganese dioxide in the solid component and form a regenerated manganate salt, which may be recycled back to the oxidation reactor.Type: GrantFiled: December 12, 2013Date of Patent: July 12, 2016Inventors: Veera Venkata Ramakrishna Tammana, Kareemuddin M. Shaik, Guillaume Robert Jean-Francois Raynel
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Patent number: 9388111Abstract: Disclosed is a method for purifying aromatic dicarboxylic acid such as isophthalic acid or terephthalic acid. The process treats a crude carboxylic acid (CCA) composition by feeding a CCA composition comprising a liquid and a solid to a filter cake formation zone to form a CCA wet cake composition and a first mother liquor stream; dewatering said CCA wet cake composition to form a dewatered CCA wet cake composition having a second liquid level that is lower than the first liquid level or having no liquid level and a second mother liquor stream; and washing the dewatered CCA wet cake composition with a wash stream in a wash zone to forma washed CCA wet cake composition and a wash liquor stream.Type: GrantFiled: December 27, 2013Date of Patent: July 12, 2016Assignee: Eastman Chemical CompanyInventors: Kenny Randolph Parker, Jennifer Caroline Moffitt, Kevin John Fontenot
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Patent number: 9388112Abstract: This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.Type: GrantFiled: January 6, 2011Date of Patent: July 12, 2016Assignees: The University of British Columbia, Brittish Columbia Cancer Agency BranchInventors: Marianne D. Sadar, Nasrin R. Mawji, Carmen Adriana Banuelos, Raymond J. Andersen, Javier Garcia Fernandez
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Patent number: 9388113Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.Type: GrantFiled: October 1, 2015Date of Patent: July 12, 2016Assignee: Laurus Labs Private LimitedInventors: Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Vamsee Krishna Muppidi, Satyanarayana Chava
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Patent number: 9388114Abstract: Compositions comprising an alkyl 3-hydroxybutyrate and one or more additional components are provided. The compositions of the present invention may include at least one alkyl 3-hydroxybutyrate having at least 3 and not more than 5 carbon atoms, along with one or more additional components including, for example, alkyl butyrates, alkyl acetates, alkyl alcohols, and dimers and/or trimers of the alkyl 3-hydroxybutyrate. Such compositions may be products of, for example, the hydrogenation of an acetoacetate-containing composition.Type: GrantFiled: August 2, 2013Date of Patent: July 12, 2016Assignee: Eastman Chemical CompanyInventors: Garry Kenneth Weakley, Charles Everette Kelly, Therese T. Golob
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Patent number: 9388115Abstract: A process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms, is characterized in that a mixture of the starting compounds is allowed to react in the presence of a Lewis acid containing at least one element of groups 4 to 14 of the periodic table of the elements as a catalyst and in the presence of an adsorbent with removal of the water formed, and then the crude ester obtained is aftertreated by adding a further adsorbent which is an acidic activated carbon having a pH of 1 to 6.5.Type: GrantFiled: January 28, 2016Date of Patent: July 12, 2016Assignee: OXEA GMBHInventors: Guido D. Frey, Tonia Weber, Jörg Arnold, Thorsten Kreickmann, Heinz Strutz
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Patent number: 9388116Abstract: A process for making esters from organic acids by means of reacting a carboxylic acid with dialkylcarbonate in an alcohol-containing solvent without any extrinsic acid or base catalyst is described. A benefit of the preparation process is that it can make the separation and extraction of ester products simpler and more facile vis-a-vis conventional isolation techniques.Type: GrantFiled: October 11, 2013Date of Patent: July 12, 2016Assignee: Archer Daniels Midland CompanyInventors: Kenneth F. Stensrud, Mitchell J. Schultz, Padmesh Venkitasubramanian
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Patent number: 9388117Abstract: The object of the present invention is to provide a process for producing ?-fluoroacrylic acid ester at a high starting material conversion, high selectivity, and high yield. The present invention provides a process for producing the compound represented by the formula (1) wherein R represents alkyl optionally substituted with one or more fluorine atoms, the process comprising step A of reacting a compound represented by the formula (2) wherein X represents a bromine atom or a chlorine atom with an alcohol represented by the formula (3) wherein the symbol is as defined above, and carbon monoxide in the presence of a transition metal catalyst and a base to thereby obtain the compound represented by the formula (1).Type: GrantFiled: August 30, 2013Date of Patent: July 12, 2016Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Tatsuya Ohtsuka, Akihiro Gotou, Sumi Ishihara, Yoshihiro Yamamoto, Akinori Yamamoto, Yoshichika Kuroki, Yuzo Komatsu, Yousuke Kishikawa
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Patent number: 9388118Abstract: A continuous process for preparing (meth)acrylates of C10-alcohol mixtures by reaction of glacial (meth)acrylic acid with an isomer mixture of C10-alcohols composed of 2-propylheptanol as the main isomer and at least one of the C10-alcohols 2-propyl-4-methylhexanol, 2-propyl-5-methylhexanol, 2-isopropylheptanol, 2-isopropyl-4-methylhexanol, 2-isopropyl-5-methylhexanol and/or 2-propyl-4,4-dimethylpentanol, and the use of a diester of dicarboxylic acids which have been esterified with N-oxyl-containing compounds as polymerization inhibitors in such a process.Type: GrantFiled: September 27, 2013Date of Patent: July 12, 2016Assignee: BASF SEInventors: Ulrich Jaeger, Volker Schliephake, Ortmund Lang, Jochen Petzoldt, Tobias Johannes Korn, Virginie Bette, Claus Hechler
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Patent number: 9388119Abstract: A process for the preparation of substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds which has advantages over conventional processes with respect to higher conversions and yields, flexibility, a shorter overall route, environmentally acceptable conditions, influence of stereoselectivity such as diastereoselectivity in a targeted manner and at least partial suppression of the formation of undesired side-products and/or undesired stereoisomers, in particular undesired diastereomers.Type: GrantFiled: August 21, 2013Date of Patent: July 12, 2016Assignee: GRUENENTHAL GMBHInventors: Helmut Heinrich Buschmann, Joerg Holenz
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Patent number: 9388120Abstract: Disclosed are compounds represented by structural formula (I): methods of producing compounds represented by structural formula (I). and their use in inhibiting oxidation in an oxidizable material.Type: GrantFiled: April 17, 2014Date of Patent: July 12, 2016Assignee: Polnox CorporationInventors: Rajesh Kumar, Suizhou Yang, Vijayendra Kumar, Ashok L. Cholli
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Patent number: 9388121Abstract: Provided are novel compositions and analogs which are useful in a number of applications, indications and diseases, as well as for monitoring pharmakinetics and patient management. These compounds and analogs are applicable to treating tumors of the central nervous system, e.g., glioblastoma (GBM).Type: GrantFiled: October 11, 2012Date of Patent: July 12, 2016Assignee: Enzo Therapeutics, Inc.Inventors: Sarah Spiegel, Robert Elliot Zipkin, Jeffrey Kroll Adams
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Patent number: 9388122Abstract: It is intended to provide a radioactive tyrosine derivative represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a group selected from the group consisting of —11CH3, —11CH2CH3, —CH218F, and —CH2CH2CH218F.Type: GrantFiled: May 25, 2005Date of Patent: July 12, 2016Assignee: HAMAMATSU PHOTONICS K.K.Inventors: Kengo Sato, Hideo Tsukada
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Patent number: 9388123Abstract: Provided is a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: [in the formula, R1 to R5, A, and *1 to *3 are as defined in Description].Type: GrantFiled: November 28, 2013Date of Patent: July 12, 2016Assignee: Kyoto UniversityInventors: Takayoshi Suzuki, Yukihiro Itoh, Daisuke Ogasawara, Naoki Miyata, Tamio Mizukami, Ryuzo Sasaki, Akifumi Takaori, Masahiro Kawahara
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Patent number: 9388124Abstract: The invention relates to compounds of general formula (I) wherein R is (C1-C7)alkyl, (C2-C7)alkenyl or (C2-C7)alkynyl; wherein R is substituted with R1; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.Type: GrantFiled: December 22, 2011Date of Patent: July 12, 2016Assignee: LEO LABORATORIES LIMITEDInventors: Gunnar Grue-Sørensen, Xifu Liang, Thomas Högberg
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Patent number: 9388125Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: GrantFiled: May 11, 2011Date of Patent: July 12, 2016Assignee: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Edward H. Cheesman, Joel Lazewatsky, L. Veronica Lee, Richard R. Cesati, Richard J. Looby, Heike S. Radeke
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Patent number: 9388126Abstract: The present invention includes compounds useful in preventing, treating or ameliorating Sigma-related disorders or diseases. The compounds of the invention can modulate cellular protein homeostasis, which includes: translation initiation, folding, processing, transport, and degradation (including ubiquitin selective autophagy) of proteins. The present invention also includes methods of preventing, treating or ameliorating a Sigma-related disorder or disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a Sigma-modulating compound. The present invention also includes methods of preventing, treating or ameliorating a Sigma-related disorder or disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a Sigma-modulating compound, further comprising administering an effective amount of a compound that inhibits the ubiquitin proteasome system (UPS) and/or autophagic survival pathways.Type: GrantFiled: July 18, 2013Date of Patent: July 12, 2016Assignee: Drexel UniversityInventors: Felix J. Kim, Joseph M. Salvino
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Patent number: 9388127Abstract: The invention generally relates to compounds that function as TP antagonists for treating thrombosis and other cardiovascular, renal, or pulmonary diseases. In some embodiments, the invention provides a compound including a substituted nitro phenoxy phenyl, a sulfonylurea, and an alkyl group. In some embodiments, the invention provides a method of treating thrombosis by administering an antithrombotic compound that preferentially binds to a thromboxane receptor, has preferential binding for either TPalpha (TP?) or TPbeta (TP?) receptor subtype.Type: GrantFiled: April 17, 2013Date of Patent: July 12, 2016Assignee: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLINInventors: B. Therese Kinsella, Patrick Guiry, Helen Reid, Barry O'Connor
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Patent number: 9388128Abstract: A process for the preparation of dihalodiphenylsulfones such as 4,4?-dichlorodiphenyl sulfone or 4,4?-bis-(4-chlorophenylsulfonyl)biphenyl with high regioselectivity, at low temperature and in the absence of toxic reagents by reacting together at least one acid, sulfur trioxide and at least one halobenzene. The invented process is particularly suited for the manufacture of 4,4?-dichlorodiphenyl sulfone.Type: GrantFiled: April 12, 2012Date of Patent: July 12, 2016Assignee: SOLVAY SPECIALITY POLYMERS USA, LLCInventor: Chantal Louis