Abstract: The present invention relates to a deagglomerated glass filler for sustained ion release for imparting ion sustained-release property to a dental material for use in the dental field. The dental material means a material for use in filling, prosthetic repair, temporary sealing, temporary bonding, preparation of a prosthetic appliance, adhesion/luting, pit and fissure sealing, or the like in a dental treatment. A glass filler for sustained ion release that sufficiently continuously releases a metal ion present in a glass composition as compared with a conventional glass filler for sustained ion release has been demanded in the field of a dental material. Such an object is achieved by a glass filler for sustained ion release that is obtained by performing a silane compound treatment step and an acidic polymer treatment step and that is controlled to satisfy a specific D50 particle size relationship in each of the steps.

Abstract: A polymerizable composition includes at least one of an acrylate compound and a methacrylate compound; a barbiturate compound; an amino carboxylic acid-based chelating agent; a peroxy compound; and filler.

Abstract: Disclosed is a composition having a substrate comprising metal oxide particles. The substrate has a coating thereon that includes an organic dispersant present in a amount that renders the substrate self-dispersible. Also disclosed is a composition, such as a cosmetic composition, that includes that self-dispersible coated substrate, and a process that includes coating a particulate metal oxide with an organic dispersant to render the metal oxide self dispersible.

Abstract: A method for preparing a liquid crystal emulsion includes: a) mixing, warming and dissolving intercellular lipid ingredients, non-polyoxyethylene (POE) based non-ionic surfactant, higher fatty alcohol, oil and wax to provide an oil phase part; b) mixing, warming and dissolving water, polyol and the other aqueous phase ingredients to provide an aqueous phase part; c) adding the oil phase part to the aqueous phase part, followed by agitation; d) introducing a viscosity modifier to the mixture solution under agitation; e) subjecting the mixture solution to rapid cooling under vacuum while carrying out debubbling under vacuum; and f) filtering the mixture solution through a filtering paper or filtering cloth. Provided is a stable liquid crystal emulsion having a multilayer lamellar structure including a large amount of intercellular lipid ingredients through a process using rapid cooling. The liquid crystal emulsion has an oil phase part and an aqueous phase part.

Abstract: A nail gel composition includes a nail gel mixture and a color agent mixing therewith for forming a nail gel layer on a nail of a user. The nail gel mixture includes first through sixth chemical elements, wherein the first through sixth chemical elements are polyacrylate-15, di-hema trimethylhexl dicarbamate, phenylbis (2,4,6-trimethylbenzoyl) phosphine oxide, hema, trimethylbenzoyl di-phenylphosphine, and 1-hydroxycyclohexyl phenyl ketone respectively. The nail gel layer is dried under an exposure of one of LED light, UV light, and sunlight that no wet sticky colloid is formed after the nail gel layer is dried with glossy high shine kept on the nail more than 10 days. The nail gel layer is adapted for being removed by directly peeling off the nail gel layer on the nail in one single step.

Abstract: The present invention relates to a dentifrice composition comprising a stannous salt e.g., stannous fluoride and a water-soluble alkali metal tripolyphosphate e.g., sodium tripolyphosphate and a non-aqueous carrier and wherein the composition is substantially free of any water and does not comprise a source of zinc ions or an aqueous buffer system.

Abstract: The present invention relates to processes for the preparation of compounds of the formula (Ia) by reacting styrene with a secondary alkanol and the hydrogenation of the resulting phenyl-substituted tertiary alkanol. In addition, the invention relates to compounds of the formula (Ia) and to the use of such compounds as fragrances, and also to compositions which comprise compounds of the formulae (Ia) and (Ib).

Abstract: A hair dye composition containing a carbonate also includes (A) at least one selected from resorcin and its derivatives, and salts thereof, an upper limit of a compounding amount of the component (A) being 0.2% by mass or less, and (B) at least one dye selected from 5-(2-hydroxyethylamino)-2-methylphenol, 1,5-dihydroxynaphthalene, and a nitro dye.

Abstract: Compositions of reserveratrol having enhanced properties. The compositions of the invention can comprise resveratrol and one or more agents that increase the bioavailability, efficacy and/or bioactivity of the resveratrol. Compositions of the invention find use in the treatment of a variety of conditions, including skin conditions and preventative health maintenance. Methods of making the inventive compositions are also contemplated.

Abstract: A preservative composition is described that may be used in personal care products and other products for protecting the products against bacteria and fungus during production and during use. The composition can about 3 to about 15% by weight of an organic acid; about 3 to about 15% by weight of a C8-C18 fatty alcohol; about 30 to about 60% by weight of an aromatic alcohol; and about 30 to about 60% by weight of an organic solvent.

Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.

Abstract: The invention relates to a process for treating keratin fibres, in particular human keratin fibres such as the hair, comprising the application to the keratin fibres of a cosmetic composition comprising a pyridinedicarboxylic acid compound. The process makes it possible to obtain good cosmetic properties in terms of manageability of the hair and sheen, with a long-lasting effect.

Abstract: The invention relates to a hair treatment composition comprising: a) from 0.1 to 2 wt. % of selenium disulfide; b) from 0.1 to 2 wt. % of zinc pyrithione; and, c) from 0.01 to 10 wt. % of a cationic guar hydroxypropyltrimonium chloride polymer; and to the use of the composition for the treatment of dandruff.

Abstract: A method for preparing a pre-mixed foundation material with a negligible chromatic aberration includes steps of: (1) processing all raw material powder of the pre-mixed foundation material with uniform surface treatments, so as to homogenize surface properties of the raw material powder; (2) after the surface treatments, thoroughly stirring the raw material powder with a high speed for obtaining the pre-mixed foundation material; and after mixing with a high-speed mixer, post-treating the pre-mixed foundation material by a jet milling method, so as to evenly disperse powder of the pre-mixed foundation material; (3) measuring the chromatic aberration; (4) adjusting a color; and (5) monitoring the chromatic aberration, for controlling the chromatic aberration ?Ecmc<0.8. According to the present invention, with help of instruments, the chromatic aberration is digitally and quantitatively measured; varied powder is processed with the uniform surface treatments, so as to enable the uniform surface properties.

Abstract: The invention relates to a composition comprising 2% to 5% minoxidil, 0.01% to 15% finasteride and 0.01% to 15% of a prostaglandin analogue. In one embodiment, the prostaglandin analogue is latanoprost. I a preferred embodiment, the composition comprises 5% minoxidil, 0.1% finasteride and 0.03% latanoprost. The invention also relates to the use of the said composition to reduce hair loss and/or increase regrowth of hair in a human subject.

Abstract: Disclosed the use of gelatin or deeply processed gelatin materials in the preparation of hair quality-improving compositions.

Abstract: Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.

Abstract: A laminate of an artificial nail bound to a natural nail with a layer of a cyanoacrylate adhesive formulation containing a thickener, a stabilizer, and a plasticizer is as strong and durable as similar laminates but is flexible and pliable enough to bend without cracking.

Abstract: Cleansing composition comprising the following components (A), (B), and (C): (A) 0.02% by mass or larger and 10% by mass or smaller of a polymer comprising 85 to 100% by mass as constitutional units of a1: a constitutional unit represented by the formula (1): wherein R1 and R2 each represents an alkyl group having 1 to 4 carbon atoms and optionally having a hydroxy group, or a hydrogen atom, and R3 represents a hydrogen atom or a methyl group, and a2: a constitutional unit represented by the formula (2): wherein R4 represents a linear or branched alkyl group having 1 to 22 carbon atoms, and R5 represents a hydrogen atom or a methyl group; (B) 0.5% by mass or larger and 40% by mass or smaller of an anionic surfactant; and (C) water.

Abstract: The present invention relates to a liquid cosmetic composition for making up and/or caring for the lips, comprising, in a physiologically acceptable medium, at least one fatty phase containing: at least one non-volatile oil, at least one linear C18-C24 hydroxylated fatty acid, preferably 12-hydroxystearic acid, at least one additional wax other than the said linear C18-C24 hydroxylated fatty acid, at least one copolymer of vinylpyrrolidone and of at least one C2-C40 olefin, at least hydrophobic silica aerogel particles, the said composition optionally comprising water at less than 5% by weight relative to the total weight of the composition, and preferably being anhydrous.

Abstract: The present invention relates to a nail varnish composition which contains a plasticizer A) and a film-forming agent B), characterized in that the plasticizer A) comprises at least two carbonate structural units of formula (I) and has an average molecular weight of ?450 g/mol, determined by gel permeation chromatography against a polystyrene standard in tetrahydrofurane at 23° according to DIN 55672-1, and a hydroxyl functionality of ?1.5 and ?6. The invention further relates to a coating which can be obtained from the nail varnish composition according to the invention, to a substrate coated with such a coating, and to a cosmetic method for coating finger and/or toe nails, according to which method a nail varnish composition according to the invention is applied to finger and/or toe nails. The invention also relates to the use of compounds as plasticizers in nail varnish compositions which compounds contain specific carbonate structural units.

Abstract: The present invention relates to amino silicone nanoemulsions. More specifically, the present invention relates to amino silicone nanoemulsions that may be used to protect surfaces from being soiled or wetted.

Abstract: The present invention relates to a method of making an amino silicone nanoemulsions. More specifically, the present invention relates to a method of making an amino silicone nanoemulsions that may be used to protect surfaces from being soiled or wetted.

Abstract: The invention relates to a cosmetic composition comprising, in a physiologically acceptable aqueous medium, a polysaccharide modified with hydrophobic chains; a polymer comprising sulfonic groups; a (meth)acrylic acid polymer, which is preferably crosslinked, and/or an oxyethylenated silicone surfactant. Use for caring for and making up keratin materials.

Abstract: The invention provides processes for the preparation of silicone gels, and the use thereof, especially in cosmetic formulations.

Abstract: The present invention relates to an anhydrous dyeing composition which is liquid at 20° C. and comprising one or more oil liquid at 20° C., one or more direct dyes and at least one anionic surfactant and at least one nonionic surfactant for achieving intensive homogeneous colors on hair.

Abstract: The invention relates to a polymer composition suitable for high-heat application comprising: a. At least one polymer 1 having a solubility parameter ?P1; b. A thermo-releasable substance being a liquid at 200° C. and having a solubility parameter ?sub in an amount of at least 0.1 wt % with respect to the total amount of composition; and wherein the amount of thermo-releasable substance is in the range from 0.5 wt % to 70 wt % with respect to the polymer 1; wherein ?=(?sub??P1)2 is in the range from 0.5 to 24.0 and wherein the solubility parameter is calculated by the software package Synthia, Materials Studio v.6.0.0 ©2011, based on the method by J. Bicerano, Prediction of Polymer Properties, Marcel Dekker, 3rd Ed, 2002, ISBN 0-8247-0821-0; Chapter 5, and in which the E-modulus of the composition as measured according to method ISO 527-1 at 200° C. is at least 50 MPa. The invention also relates to personal care devices and hair-straighteners comprising this polymer composition.

Abstract: The object of the present invention is the cosmetic use via an oral route of a combination of actives comprising at least one polyunsaturated fatty acid and vitamin D, for improving the hair quality. This combination of actives may further comprise, as an additional active, vitamin E, vitamin C, a carotenoid, zinc gluconate or combinations thereof. The combination of actives is preferably applied in a cosmetic composition intended for oral administration, such as a food supplement.

Abstract: Provided are compositions comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, and an extract of Vaccinium subgenus Oxycoccus. The compositions may also include an extract of neem and Competence Stimulating Peptide (CSP). Also provided is a method for inhibiting the growth of Streptococcus mutans in a biofilm in the oral cavity of a subject, the method comprising administering to the oral cavity of the subject a composition comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, an extract of Vaccinium subgenus Oxycoccus, wherein administering the composition selectively inhibits the rate of growth of Streptococcus mutans over the rate of growth of at least one species of non-Streptococcus mutans bacteria in the biofilm.

Abstract: A composition comprising an extract of combined herbs Acanthopanax koreanum Nakai and Crinum asiaticum var. japonicum showing treatment activity of a hair baldness disorder and stimulating activity of hair growth. The combined extract showed potent hair-growth promoting activity and a synergistic effect compared to each herb, i.e. the sole treatment of Acanthopanax koreanum Nakai or Crinum asiaticum var. japonicum, through animal model experiments, such as, the growth rate test using C57BL/6 mouse, to confirm the effect of the combined extract, i.e. combined treatment of Acanthopanax koreanum Nakai and Crinum asiaticum var. japonicum. Therefore the extract can be useful in treating a hair baldness disorder.

Abstract: Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.

Abstract: The present invention relates to an injectable aqueous viscous solution for treating varicose veins. It also relates to a catheter system with cannulas for vascular puncture with double or triple cut tip comprising, (i) an outer cannula (non-cutting element), a tube-like construction which is slightly flexible, (a) the tip zone being tapered to ease introduction, (b) the edges being optionally rounded to provide atraumatic advancement (c) optionally with a Luer-lock connector (ii) a hollow needle which is flexible and bendable (c) optionally with a transparent flashback chamber, wherein (d) the diameter of the needle is below the diameter of the catheter, wherein (iii) the needle and outer cannula are connected by a temporary lock to ensure the needle tip is fixed in adequate position outside the outer cannula outer cannula during skin puncture and introduction towards the target region.

Abstract: Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has an amino acid sequence of SEQ ID NO:4.

Abstract: A suspension includes an ophthalmic active ingredient suspended in a formulation vehicle including a suspending agent and a non-ionic cellulose derivative. The ophthalmic active agent is present as particles having Dv90<5 ?m and Dv50<1 ?m. The suspension may be administered to a patient for treating an ophthalmic inflammatory condition.

Abstract: This disclosure features modified release pharmaceutical formulations (e.g., extended release pharmaceutical formulations; e.g., solid dosage forms, e.g., tablets) that are useful for the oral administration of oprozomib, or a pharmaceutically acceptable salt thereof, to a human or animal subject as well as methods of making and using the formulations.

Abstract: A method for treating intestinal fibrosis in a subject, comprising enterally administering a steroid to the subject. The steroid may be in a multiple minibead formulation.

Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.

Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.

Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.

Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.

Abstract: The present invention relates to chewing gum containing a synergic combination of zinc and vegetable extracts containing polyphenols. Said chewing gum is useful in treating the symptoms of halitosis.

Abstract: This invention relates to novel pharmaceutical compositions for inhalation comprising separately, sequentially or together, drugs having amine in the form of a dry powder in admixture with a pharmaceutically acceptable carrier, other than lactose, and its use in the treatment of respiratory condition selected from asthma and chronic obstructive pulmonary disease (COPD) and other obstructive airways diseases. More particulary, the invention relates to pharmaceutical composition for inhalation further comprising a ternary component. In addition, the present invention relates to novel pharmaceutical composition for inhalation based on combinations of long acting muscarinic antagonists, long acting beta agonists, short acting beta-2 agonists, corticosteroids or a combination of two or more of them.

Abstract: This invention relates to the field of pharmaceutical chemistry and, more specifically, to pharmaceutical formulations as well as to intermediates used to prepare such formulations and to methods for manufacturing such formulations.

Abstract: An object of the present invention is to provide an orally disintegrating tablet having both an excellent tablet hardness and disintegrability even when the content of a medicinal ingredient is high. This invention relates to an orally disintegrating tablet comprising a medicinal ingredient having distribution coefficient (log P) in a range of from ?6.0 to 10.0 and a disintegrative particulate composition produced by granulation consisting of at least two stages, especially to said orally disintegrating tablet having tablet hardness of from 30 to 100 N, and disintegration time in water of from 10 to 30 sec.

Abstract: The present invention relates to novel tablet dosage forms and methods of preparing these forms, which can be used for different classes of pharmaceutical active ingredients posing stability issues in a single unit system. The dosage form includes a first layer, which includes a tablet of one or more active pharmaceutical ingredients, which is inlayed in the first layer along with other pharmaceutically acceptable excipients, and a second layer that includes one or more active pharmaceutical ingredients optionally with other pharmaceutically acceptable excipients.

Abstract: Disclosed are a controlled release pharmaceutical composition, comprising a melt-extruded pellet including a water-insoluble ammonium methacrylate copolymer, a polyvinyl acetate, and an active ingredient; and a polymer coating layer including a water-insoluble ammonium methacrylate copolymer formed on the surface of the pellet, and an oral formulation including the pharmaceutical composition.

Abstract: Provided are novel methods and compositions for administration of pharmaceuticals to subjects with dysphagia. Pharmaceuticals are associated with beads and administered with food, beverage or cosmetic to provide ease of administration to subjects with dysphagia. Environmental indicators are associated with beads for Quality Assurance.

Abstract: The present invention relates to a bicyclic compound of Formula (I) and to a composition for a cosmetic and therapeutic use and to a composition comprising an acceptable vehicle and an effective amount of the compound of Formula (I):

Abstract: The present invention provides a novel emulsion composition in a stable, fast acting emulsion that contains cannabidiol in an aqueous vehicle. The cannibidiol is extracted using CO2 from an industrial hemp plant that produces cannibiodiol molecules surrounded by less fats and waxes making it more hydrophilic. A little emulsifying agent, such as polysorbate 80, is mixed with cannabidiol oil to create a stable first emulsion mixture. A batch mixture is then prepared containing water, food preservatives, sugar, a sufficient amount of CBD Premix that contains citicoline and masker A for Reb A. Both mixtures are then mixed in water with ginger, Vitamin C, Vitamin B6, Vitamin B12, and sugar.

Abstract: A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic injury, stroke, Huntington's disease, Epilepsy, Multiple Sclerosis (MS), Lupus, Type-1 and Type-2 diabetes, Maturity Onset Diabetes of the Young (MODY), myasthenia gravis (MG), rheumatoid arthritis (RA), Graves' disease, Guillain-Barré syndrome (GB S), metabolic syndrome, Muscular Dystrophy or Duchenne Muscular Dystrophy (DMD), severe burns, aging, Amyotrophic Lateral Sclerosis (ALS), Friedreich's Ataxia, Batten Disease, Alzheimer's disease, optic neuritis, Leber's hereditary optic neuropathy (LHON), autism, Rett syndrome, Batten Disease, Angelman's Syndrome, Leigh disease, Fragile-X Syndrome, depression, Parkinson's disease, mitochondrial diseases, developmental disorders, metabolic disease disorders and/or autoimmune disorders by inducing endogenous BDNF expression with DNP treatment to protect from neuromuscular dysfunction/disorders and/or neurodeg