Abstract: A method of treating Peyronie's disease through implantation of a supporting structure in a penis suffering from a Peyronie's plaques affected area includes providing an incision in the penis and accessing the Peyronie's plaques affected area. The method includes excising plaque out of the Peyronie's plaque affected area and exposing exposed tissue of the penis, and placing an implant on the exposed tissue of the penis. The implant has a sheet component attached to a reinforcing component. The method includes positioning the implant allowing for tissue ingrowth into the sheet component and providing column strength to the exposed tissue of the penis with the reinforcing component of the implant, and securing the implant subcutaneously to the penis prior to closing the incision.

Abstract: Porous biocompatible composite biomaterial, useable as a drug delivery system or as spacer or as bone substitute, such as for example for filling bone lacunae or for substituting damaged parts of bone tissue, or for fixing prosthesis of various types, or for thickening bones weakened by illness such as osteoporosis or the like, including a component adapted to form a porous structural matrix and a soluble component, wherein the soluble component is in form of powder and granules or other similar agglomerates so as to have mechanical support characteristics and osteoinductive and osteoconductive characteristics in the entire volume occupied by the biomaterial, and a method for obtaining the biomaterial.

Abstract: The present disclosure relates to a method incorporating computer-implemented steps, a computing device, a computer readable storage medium, and a client computing device for modelling the alignment of an orthopedic implant for a joint of a patient. The method comprises the computer-implemented steps of being responsive to patient specific information data for deriving patient data, where the patient specific information data is indicative of one or more dynamic characteristics, and being responsive to the patient data for providing 3D model data of the joint, such that the 3D model data shows the orthopedic implant in an alignment configuration based on the patient specific information data.

Abstract: An orthopaedic augment includes a porous material, which is removably attached to a medical implant. The porous material has a bone ingrowth surface for interfacing with an existing bone material and another surface for interfacing with the medical implant.

Abstract: A system of surgical instruments for use with at least a first implant and a second implant of the same type but different sizes is provided. The system includes at least three containers. The first container contains at least a first surgical instrument of a first type that is size specific and a second surgical instrument of a second type that is size specific; both the first and second instruments are of a first size The second container contains at least a third surgical instrument of the first type and a fourth surgical instrument of the second type; both the third and fourth instruments are of a second size which is different from the first size. The third container contains at least a fifth surgical instrument of a third type which is size independent.

Abstract: A reusable orthopedic instrument includes a reusable orthopedic trial having a first outer surface and a second outer surface that is opposite the first outer surface. A notch is formed in each side of the orthopedic instrument.

Abstract: A tibial component for implantation at a resected tibia. The tibial component includes a medial tray, a lateral tray, and a connection member between the medial tray and the lateral tray. A first fastener extends from the medial tray to the connection member along a first pivot axle to pivotably couple the medial tray to the connection member. A second fastener is spaced apart from the first fastener and extends from the lateral tray to the connection member along a second pivot axle to pivotably couple the lateral tray to the connection member. The medial tray and the lateral tray are configured to pivot independently of one another with respect to the connection member.

Abstract: A posterior cruciate ligament retaining knee implant prosthesis comprising a femoral component including a medial condyle and a lateral condyle separated from one another by an intercondylar channel adapted to accommodate throughput of a native cruciate ligament, both the medial condyle and the lateral condyle posteriorly terminate individually, the medial condyle including a medial condyle bearing surface and the lateral condyle including a lateral condyle bearing surface, the femoral component including an anterior cam, and a tibial component including a medial condyle receiver having a medial condyle receiver bearing surface, the tibial component also including a lateral condyle receiver having a lateral condyle receiver bearing surface, the tibial component also including an anterior post.

Abstract: A tibial prosthesis assembly including a tibial component and a tibial insert. The tibial component includes an inferior bone engaging surface, a superior surface, and a first retention feature. The tibial insert includes an inferior tibial component engaging surface, a superior bearing surface, and a second retaining feature. The first and the second retaining features cooperate to mate the tibial insert with the tibial component at one of a plurality of fixed rotational orientations relative to the tibial component.

Abstract: According to one aspect of the present invention, there is provided a tibial component (10), suitable for use in an orthopedic prosthesis, which prosthesis includes a femoral component and a spacer bearing (70), the tibial component comprising a planar tibial plate (15) having an upper bearing surface (30) and a lower attachment surface (20), and the tibial plate further having at least one spacer bearing attachment means for removably securing the spacer bearing to the tibial plate.

Abstract: A trapeziometacarpal joint implant includes a body defining a median plane, a metacarpal joint surface, and a trapezium joint surface. A first central region of the metacarpal joint surface is situated on an opposite side of the median plane from a second central region of the trapezium joint surface. The first and second central regions correspond to profiles of a first axial segment and a second axial segment, respectively. The first and second axial segments are one of a cylinder, a cone and a torus and are centered on a first axis and a second axis, respectively, where the first and second axes, as projected on the median plane, are substantially perpendicular to each other.

Abstract: Methods and apparatuses for restoration of human or animal bone anatomy, which may include introduction, into a bone of an expansible implant capable of expansion in a single determined plane, positioning the expansible implant in the bone in order to correspond the single determined plane with a bone restoration plane and opening out the expansible implant in the bone restoration plane. A first support surface and a second support surface spread tissues within bone. The embodiments of the invention may also include injecting a filling material around the implant.

Abstract: An implantable orthopedic stability device is disclosed. The device can have a contracted and an expanded configuration. A method of using the device between adjacent facet surfaces for support and/or fixation of either or both of the adjacent vertebrae is also disclosed.

Abstract: Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.

Abstract: An intervertebral device comprises a plurality of struts that are rotatably associated with each adjacent strut to form a modifiable inner volume V for bone graft containment.

Abstract: A unitary intervertebral device, having no moving components is provided for non-fusion articulation applications. The interbody articulating device allows for limited flexion and rotation between adjacent vertebrae, helping to preserve or restore near-normal motion between adjacent vertebrae. Rotational motion is achieved through one or more protrusions incorporated into the spinal interbody device. In one articulating form, a first protrusion extends perpendicularly from the superior aspect of the disc-shaped interbody device to form a spike or rotational protrusion, while a second protrusion extends axially from the inferior aspect of the interbody device to form a second spike or rotational protrusion. Protrusions preferably extend perpendicular from the apex of both the first and second arcuate articulating surfaces.

Abstract: Deflectable implants, systems and methods for implanting deflectable implants are disclosed. The deflectable implant includes at least one sequence of segments, the sequence includes at least two segments, the segments being interconnected at effective hinges, the sequence assuming a straightened or low curvature insertion state for insertion into the body, the sequence being deflectable to a fully deflected state defined by abutment of abutment features of adjacent of the segments.

Abstract: A flexible implant system for positioning a flexible spacer between adjacent vertebrae including and interbody spacer and an insertion instrument. The interbody spacer including a central axis, a lateral axis, a top surface positioned generally parallel to the central axis and a plurality of hinge sections extending generally perpendicular to the central axis. A plurality of notches making up the plurality of hinge sections adjacent the top surface that permit the interbody spacer to flex. The interbody spacer further including a groove extending along a lateral side surface, generally parallel to the central axis. An insertion instrument includes a proximal end, a distal end and a tongue extending from the proximal end to the distal end along a non-linear path. The groove slidably engages the tongue to guide the interbody spacer from the proximal end to the distal end along the non-linear path.

Abstract: An improved artificial disc has a superior and inferior member. The superior member has an upper body portion and a flange portion for positioning and attachment to an upper vertebral body. The inferior member has a lower body portion and a flange portion for positioning and attachment to a lower vertebral body. The upper body portion and the lower body portions, when positioned in a disc space between the upper and lower vertebral bodies and affixed to a respective vertebral body at the flange portion, are independently movable relative to the other along complimentary bearing surfaces on each of the superior and inferior members. The complimentary bearing surfaces are self-aligned by a magnetic attraction force generated by at least one first permanent magnet in either the inferior or superior member.

Abstract: Arcuate fixation members with varying configurations and/or features are provided, along with additional components for use therewith in provided fixation systems and intervertebral implant systems. The arcuate fixation members may be of varying lengths, cross sectional geometries, and/or cross sectional areas, and may be configured with various features such as heads configured to accept other fixation system components, tabs to allow arcuate fixation member-in-arcuate fixation member or fixation anchor-in-arcuate fixation member configurations. Applications of fixation systems and intervertebral implants systems utilizing arcuate fixation members are particularly suitable when a linear line-of-approach for delivering fixation members is undesirable.

Abstract: A system includes tubular members removably positionable over a passageway device connected to a connecting element attached to a vertebra. The tubular members may each include a sidewall having an opening positionable adjacent a proximal end of the passageway device when the tubular member is positioned over the passageway device. The tubular members include channels therein to receive respective blades of the passageway devices. One of the tubular members may be a counter torque tube, and another two of the tubular members may be a hinge shaft and a ball shaft, respectively, of a compression and distraction system. The blades of each passageway device may be integrally formed with a cage of the connecting element to form a monolithic blade-screw. The blades of the monolithic blade-screw may be constructed by affixing distal ends of non-threaded blade extensions to proximal ends of threaded reduction portions integrally connected to the cage.

Abstract: An expandable interbody device for implantation within an intervertebral space is provided, together with methods and tools for use therewith. The interbody devices include a leading first and trailing second bearing member configured to expand laterally via connecting portions disposed at the trailing end of the first being member and at least the leading end of the second bearing member. In some forms, the connecting portions have an arcuate configuration. The insertion tool is configured expand the interbody device by holding the first bearing member while shifting the second bearing member.

Abstract: An inter-vertebral implant having a hollow frame having a top load bearing surface and a bottom load bearing surface may be inserted between a first spinal vertebra and a second spinal vertebra. The top load bearing surface and the bottom load bearing surface may each include an opening allowing access to the interior of the frame. A front surface may extend between the top load bearing surface and the bottom load bearing surface, and a rear surface may extend between the top load bearing surface and the bottom load bearing surface. A plate is attached to the front surface of the support device. The interior front plate may be arranged along a plane (P), and an axis (A) between the top load bearing surface and the bottom load bearing surface may be at a non-right angle relative to the plane (P).

Abstract: An intervertebral prosthesis or disk prosthesis comprising a front side, a rear side, an upper side which can be placed on the base plate of vertebral body, a lower side which can be placed on the base plate of a vertebral body, a right side, a left side, a cavity which can receive a fluid hydraulic osteocementum, an opening in the cavity and several outlets out from the cavity. The total of the transversal surfaces of the outlets SV on the front side, the total of the transversal surfaces of the outlets SH on the rear side, the total of the transversal surfaces of the outlets SR on the right side and the total of the transversal surfaces of the outlets on the left side satisfy the following conditions: SL>SR or SR>SL or SH>SV or SV>SH.

Abstract: An orthopedic implant inserter is provided with removable jaws. The jaws are connected to handles of the inserter by retainers. Each retainer includes a shaft and a latch. The shaft is configured to be received within mounting bores of a jaw and the associated handle. The latch is connected to the shaft and movable between a release configuration and a retaining configuration. In the release configuration, the shaft is removable from the mounting bores and the jaw is thereby removable from the associated handle. In the retaining configuration, the shaft is secured within the mounting bores and the jaw is thereby secured to the associated handle.

Abstract: A delivery instrument for placing an interbody implant into an intervertebral space of a patient comprises a plurality of elongated plates disposed adjacent one another. Each elongated plate has a proximal portion and a distal portion. The distal portion is sized and shaped to fit into the intervertebral space, and is configured to engage a vertebral body in the intervertebral space. An expandable member is coupled to the plurality of elongated plates so as to form an enclosed tube that is sized and shaped to receive the interbody implant. The expandable member allows for translation of the plurality of elongated plates relative to one another as the interbody implant passes through the tube.

Abstract: An external breast prosthesis having a thin-walled outer shell and an air-filled interior cavity. The prosthesis is fabricated using a method and die set to form the two-part shell without internal supporting structure. The method provides a repeatable process which yields a prosthesis having durable air-tight seal between the anterior and posterior shell and a Class-A exterior surface which accurately replicates the visual and tactile characteristics of a human breast.

Abstract: The invention relates to a connection device for connecting an implant system anchored in bone with an external prosthesis component, such as a limb prosthesis, prosthetic knee elbow or finger. The connection device includes a main housing, a first attachment portion arranged for attachment to the implant system and a second attachment portion arranged for attachment to the prosthesis component. It further includes a safety mechanism to protect the implant system from high mechanical forces, including rotational forces and or bending forces. According to one aspect of the invention the safety mechanism includes a rotational force release mechanism. This includes a first component including a ring unit having an inner surface with at least one depression and a second component includes at least one plunge unit urged into contact with said the depression by said spring means.

Abstract: A valve device regulates the air pressure in the space between a residual limb, or liner-covered limb, and a hard socket of an external prosthesis. A manually-controlled air-outlet and -inlet valve may optionally include an automatic one-way valve (or “expulsion” valve). The manually-controlled valve is opened and closed by twisting a handle, to open a two-way air passageway by slightly separating the handle and base portions, or by aligning bores in the handle and base portions. At least one stop surface limits the amount of relative rotation of the handle and base portions of the valve, so that the user need only rotate the handle a small amount, for example, less than 90 degrees, to affect opening or closing the valve.

Abstract: A pin lock for a prosthetic device in a vacuum assisted suspension system includes a pin defining a longitudinally elongate bore and at least one passageway extending obliquely relative to the bore and communicating therewith at a proximal end of the pin. The pin lock also includes a locking mechanism having a receiving port arranged to receive the pin and a channel located at a distal end of the receiving port and adapted to communicate with the bore to exhaust air through the pin therefrom.

Abstract: Various embodiments of a system and method for sealing a prosthetic socket are disclosed. One example socket sealing system may comprise: a prosthetic socket having a proximal end, an expanded section, and an internal peripheral shoulder; a brim seal having an inner proximal end, an outer proximal end, and a distal end; a removable brim having a distal end; a liner; and a wicking sock; wherein prosthetic socket may be oriented radially outwardly of the outer proximal end of the brim seal, the outer proximal end of the brim seal may be oriented radially outwardly of the removable brim, the removable brim may be oriented radially outwardly of the inner proximal end of the brim seal, the inner proximal end of the brim seal may be oriented radially outwardly of the wicking sock, and the wicking sock may be oriented radially outwardly of the liner; and wherein the brim seal may be reflected about the distal end of the removable brim.

Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

Abstract: A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; deploying an occlusion device across the aneurysm; producing an image of the aneurysm including the contrast agent; and withdrawing the delivery device from the vessel after observing that the aneurysm has been obstructed by a desired amount. The image may be two-dimensional or three-dimensional. Observing that the aneurysm has been obstructed may include determining a degree of obstruction, for example by comparing an area or volume of the contrast agent in a first image and a second image. The desired amount may be a certain degree of obstruction, identification of a shape indicative of stasis such as a flat surface, an approximate hemisphere, a mushroom, or a crescent. If the occlusion device does not achieve the desired amount, a second occluding device may be deployed.

Abstract: A woven, self-expanding stent device has one or more strands and is configured for insertion into an anatomical structure. The device includes a coupling structure secured to two different strand end portions that are substantially aligned with each other. The two different strand end portions include nickel and titanium. The coupling structure is not a strand of the device.

Abstract: A woven, self-expanding stent device has one or more strands and is configured for insertion into an anatomical structure. The device includes a coupling structure secured to two different strand end portions that are substantially aligned with each other. The two different strand end portions include nickel and titanium. The coupling structure is not a strand of the device.

Abstract: A prosthesis adapted for inter-luminal placement by endovascular deployment for the treatment of vascular dissection, the prosthesis has a self expanding stents (38) connected together to define an elongate lumen wall engaging surface. At least one of the stents has a bio-compatible graft material cover (36) to define a covered portion (25). The cover is adapted to close off a rupture (7) in the wall of the lumen (6) and the stents are adapted to provided pressure on the wall of the lumen adjacent to and extending away from the rupture.

Abstract: An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form. A plurality of regions of each backbone may have a recessed or “nesting” profile providing for a smaller overall stent profile in a compacted configuration, and improved stent retention as mounted on a balloon catheter.

Abstract: A rotatable connection between a tubular member and an elongate wire of a catheter for allowing rotational movement of the tubular member relative to the elongate wire. The rotatable connection includes a first tube secured to the tubular member and a second tube secured to the elongate wire. The second tube is disposed around the first tube and rotatable relative to the first tube. The longitudinal axis of the tubular member is offset from the longitudinal axis of the elongate wire to allow a guidewire to extend through the tubular member and along the side of the elongate wire.

Abstract: A method of implanting a prosthesis in a patient at a treatment site within a blood vessel includes advancing an outer catheter of a prosthesis delivery system in the patient distal to the treatment site, the outer catheter defining an inside diameter and advancing an inner sheath, having greater flexibility than the outer catheter and an outside diameter that is greater than the inside diameter of the outer catheter, and a guidewire lumen of the delivery system from the outer catheter to the treatment site along a guidewire while the outer catheter remains stationary relative to the patient, whereby advancing the inner sheath delivers the prosthesis to the treatment site. The inner sheath is retracted to deploy the prosthesis from within the inner sheath and at the treatment site after which the delivery system from the patient.

Abstract: A method of implanting a prosthesis in a patient at a treatment site includes advancing an outer catheter of a prosthesis delivery system in the patient distal to the treatment site. An inner sheath and a curved guidewire lumen of the delivery system are advanced from the outer catheter to the treatment site along a guidewire while the outer catheter remains stationary relative to the patient. Advancing the inner sheath causes rotation of the prosthesis to thereby rotationally align the prosthesis at the treatment site. The inner sheath is retracted to deploy a prosthesis from within the inner sheath and at the treatment site. The delivery system is then retracted from the patient.

Abstract: Device useful for implanting an implantable device within the vasculature of a patient. The device includes a deployment line, a control component for actuating the deployment line, and an actuation mechanism for translating constant-rate actuation of the control component into variable rate retraction of the deployment line from a remotely deployable implantable device. Suitable implantable devices include, for example, stents and stent grafts.

Abstract: Orthopedic braces and splints for use on a limb of an animal, that provide stability for unstable joints and limbs for short or long term support and function. These orthoses are designed to prevent the occurrence of, or reduce the severity of, a joint injury. These braces and splints can also be fitted immediately after corrective surgery, and can support and stabilize the joint while assisting or restricting the range of motion. Various embodiments of the orthoses are modular, thermoformable and may include an adjustable tensioning system, which in combination provide a custom fit for a wide variety of animals and injuries.

Abstract: The present invention includes a walking boot device which immobilizes the ankle at about a 90° angle using a single anterior post that is angled at about 90° at an ankle joint from a lateral view, and encompasses an anterior one half of a calf proximally, and a dorsal one half of a forefoot distally. The post includes medial and lateral wings. The present invention defines an area for a medial and lateral malleolus and is narrow at the ankle and wider at the calf for a more anatomical fit. The present invention is secured to a leg using hook and loop fastener (Velcro®) strapping attached proximally around the calf posteriorly, away from any bony prominences. The hook and loop fastener (Velcro®) strapping is attached to the medial and lateral wings through brackets that are riveted into the wings. The present invention further includes foam inserts and a pneumatic bladder.

Abstract: This document provides methods and materials related to relieving neck pain. For example, neck pain relieving devices as well as methods for making and using neck pain relieving devices to provide relief from chronic or acute neck pain by providing support to the back of the head are provided.

Abstract: A tissue retention system to assist in maintaining adipose tissue on a patient in a displaced position during a medical procedure to provide access to a body region of the patient includes a flexible anchor pad having a pad length and a pad width. The anchor pad may include a pad body with an adhesive surface thereon, the adhesive being configured to selectively adhere to a patient's skin. The anchor pad also may include an opposing first attachment surface facing away from the adhesive surface. The tissue retention system also may include a flexible tension member having a second attachment surface.

Abstract: Methods and devices are disclosed for manipulating the tongue. An implant is positioned within at least a portion of the tongue and may be secured to other surrounding structures such as the mandible and/or hyoid bone. In general, the implant is manipulated to displace at least a portion of the posterior tongue in an anterior or lateral direction, or to alter the tissue tension or compliance of the tongue. Methods and devices for adjusting a glossopexy system are also disclosed. Adjusting a distance between two body-engaging structures can be performed without disengaging a tether from either of the body-engaging structures in some embodiments.

Abstract: Apparatus for reducing obstructive sleep apnea, snoring and/or nasal drainage. One apparatus includes an upper member fitting the interior and exterior surfaces of a user's upper dentition, and a lower member fitting similarly adjacent a user's lower dentition. The lower member includes eyeteeth extensions projecting away from the lower member. The upper member includes molar extensions projecting away from the upper member and toward the member molar regions so that when the user bites or clenches, the upper right and lower right extensions impinge on one another in substantially overlapping fashion, as do the upper left and lower left extensions. The upper and lower members have an anterior shape to form a gap sufficient for the user's tongue to extend into the gap, and each molar extension may include a magnet. Methods of using the apparatus and kits to reduce sleep apnea, snoring, and/or nasal drainage.

Abstract: A therapeutic device for relieving an affected organ or part of the body comprises a mass of material such as beeswax which in use is capable of maintaining a temperature range of 36 to 38 degrees Celsius at the affected part of the body when retained on the skin near the affected part. The invention also extends to articles of apparel containing such a therapeutic device.

Abstract: A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.

Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.