Abstract: An intravaginal imaging device, method and system are disclosed. The imaging device is housed within an elongated housing having a proximal end and a distal end. The distal end includes a sealing endcap window, an objective disposed behind the window having first lens group and a second lens group configured to focus on a target, an image detector disposed behind the objective configured to detect an image from the objective, and a LED light source disposed behind the window configured to illuminate the target. A connecting portion in communication with the image detector is disposed at the proximal end. The connecting portion is configured to convey an image from the image detector to an external device. The intravaginal imaging device is configured to be used in conjunction with a speculum where the intravaginal imaging device is inserted within jaws of the speculum and positioned within the spacers of the speculum.

Abstract: A medical system generally comprises a camera head, a beam, and a guide sheath. The camera head is connected to the beam which is bendable in a first direction and resists bending in a second direction opposite the first direction. The guide sheath slidably receives the beam, the beam extending through a distal end of the guide sheath such that the camera head projects from the distal end of the guide sheath. The guide sheath includes first and second sheath portions, and in an operative configuration the first sheath portion is angled relative to the second sheath portion to define a first bend. The beam is oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the first direction through the first bend, and a projecting portion of the beam resists bending in the second direction.

Abstract: A system for predicting optical power for an intraocular lens based upon measured biometric parameters in a patient's eye includes: a biometric reader capable of measuring at least one biometric parameter and a representation of a corneal topography of the patient's eye; a processor coupled to a computer readable medium having stored thereon a program that upon execution causes the processor to receive the at least one biometric parameter and obtain corneal spherical aberration based upon the representation of the corneal topography, and the processor calculates an optimized optical power to obtain a desired postoperative condition by applying the received value and obtained corneal spherical aberration to a modified regression, wherein the modified regression is of the form: optical power=Regression+constant0*(corneal spherical aberration) or optical power=constant1*(biometric parameter)+constant0*(corneal spherical aberration).

Abstract: An optical coherence tomography (OCT) system includes: a light source; a multi-focal delay line; and a light detector. The multi-focal delay line includes: a positive lens; and an optical switch configured to: receive a light from the light source; selectively direct the sample light to the positive lens via a selected one of a plurality of light interfaces each located a different distance from the focal plane of the positive lens; and direct the sample light to an object to be measured. The light detector is configured to receive return light returned from the object to be measured in response to the sample light, and to receive a reference light produced from the light from the light source, and in response thereto to detect at least one interference signal. An associated OCT method may be performed with the OCT system.

Abstract: An improved fundus imager for recording an image of a fundus of an eye is described. A line from a point on the fundus at a center of the image to a center of a pupil of the eye defines an axis. The fundus imager includes at least a source of illuminating light, optics for directing the illuminating light to the fundus of the eye, and a rotating element for rotating the illuminating about the axis such that the illuminating light illuminates the fundus at a plurality of locations around the axis. In a preferred embodiment of the present application, the rotating element is a rotating slit-shaped illumination aperture. In an alternate embodiment, the rotating element is a Dove prism for rotating the illuminating light on the fundus.

Abstract: Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In another embodiment, segmentation of layers in the retina includes both structural and flow information derived from motion contrast processing. In a further embodiment, the health of the eye is evaluating by comparing a metric reflecting the density of vessels at a particular location in the eye determined by OCT angiography to a database of values calculated on normal eyes.

Abstract: Computer aided visualization and diagnosis by volume analysis of optical coherence tomography (OCT) angiographic data. In one embodiment, such analysis comprises acquiring an OCT dataset using a processor in conjunction with an imaging system; evaluating the dataset, with the processor, for flow information using amplitude or phase information; generating a matrix of voxel values, with the processor, representing flow occurring in vessels in the volume of tissue; performing volume rendering of these values, the volume rendering comprising deriving three dimensional position and vector information of the vessels with the processor; displaying the volume rendering information on a computer monitor; and assessing the vascularity, vascular density, and vascular flow parameters as derived from the volume rendered images.

Abstract: An eye examination device may include a body defining a handle and a retainer for a minor. The device may further include a projection having a predefined length from the body. The predefined length of the projection is defined by a focal length of the minor. The device may further include a light integrated in the retainer adjacent to the minor.

Abstract: An ophthalmologic imaging apparatus that captures an image of a subject's eye is provided. The apparatus includes a focusing unit configured to focus light returned from the subject's eye that is illuminated by the light of a first wavelength, onto an imaging unit, and a moving unit configured to move the focusing unit based on an optical path length difference between the light of the first wavelength and the light of a second wavelength that is different from the first wavelength when light returned from the subject's eye that is illuminated by the light of the second wavelength is focused onto the imaging unit.

Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

Abstract: The present invention relates to an infant body temperature and sleep monitoring system including a Bluetooth body temperature thermometer main body, an arm belt and a Bluetooth receiving member; the Bluetooth body temperature thermometer main body is connected to a first side of the arm belt via a first adhesive strap; a second side of the arm belt is disposed with a fastening ring at a first end and a second adhesive strap at a second end; the second end of the arm belt which is disposed with the second adhesive strap passes through the fastening ring and engages with the second adhesive strap so that the arm belt forms a tightness-adjustable annular belt; the Bluetooth body temperature thermometer main body obtains body temperature data and transmits the body temperature data to the Bluetooth receiving member. The present invention is simple in structure, convenient and practical and easy to wear.

Abstract: A miniature, low-power, optical sensing device that operates in the harsh electromagnetic environment of a magnetic resonance imaging system is provided. The device includes a means of transferring imaging data obtained with the optical sensor out of this harsh electromagnetic environment without requiring a galvanic connection. It is practical to power the device using a small battery that is compatible with the harsh environment. In other embodiments, the device is powered using ‘power over fiber’ or by taking power by ‘power harvesting’ directly from the harsh electromagnetic environment. One embodiment is to directly integrate the device into a magnetic resonance imaging (MRI) head coil, using a wired connection to the head coil to provide electrical power. Here the wired connection does not penetrate the Faraday cage of the MRI system or cross into the bore of the MRI system from outside the bore.

Abstract: An exemplary system, apparatus, method and computer-accessible medium for determining information regarding a sample(s), can be provided, which can include, for example, a source arrangements(s) which can provide a first radiation(s), whose intensity can vary over time, to the sample(s), a detector arrangement(s) which can be configured to receive a second radiation(s) from the sample(s) based on the first radiation(s) and a computer arrangement(s) which can be configured to simultaneously determine the information regarding the sample(s) at a plurality of frequencies of the second radiation(s).

Abstract: The present invention relates generally to nanowires, nanospheres and microspherical structures derived from keratin, such as bird feathers. Such structures may be utilized to form biodegradable, organic, non-toxic solar cells for the purpose of propagating energy in a circuit of an electronic device. Structures of the present invention can also be utilized in pharmaceutical delivery devices and biosensing purposes, in particular, detecting cancerous cells in vivo.

Abstract: According to an image diagnosis device for photographing a breast by using the matching of a tactile image and a near-infrared image and a method for acquiring a breast tissue image, provided in the present invention, a tactile image and a near-infrared image are simultaneously acquired through a tactile image acquisition unit and a near-infrared image acquisition unit, the acquired images are mapped to a pre-stored breast model so as to match the two images, and a simple, economic and accurate early diagnosis for a breast cancer is enabled without any help from a doctor by simultaneously deriving an elasticity distribution and a hemoglobin distribution of the breast.

Abstract: Provided is an object information acquiring apparatus having: a light source; an optical transmission system that transmits light from the light source; a photoacoustic probe including an irradiating end that irradiates the light onto an object and a receiver that receives an acoustic wave generated from the object, onto which the light is irradiated; a processor that acquires information on the object interior on the basis of the acoustic wave; a display device that displays information on the object interior; a holder that stores the photoacoustic probe and covers the irradiating end; and a light quantity meter that measures quantity of irradiated light, wherein the irradiating end can irradiate light in a state being cover by the holder.

Abstract: A method implemented by a device to measure a bodily parameter includes transmitting, by a transmit (Tx) antenna of an antenna pair, a first radar pulse to a receive (Rx) antenna of the antenna pair. The method also includes receiving, by the receive (Rx) antenna, the first radar pulse. The first radar pulse travels through a radar target between the Tx antenna and the Rx antenna. The method further includes transmitting, by the Tx antenna, a second radar pulse to the Rx antenna. In addition the method includes receiving, by the Rx antenna, the second radar pulse, wherein the second radar pulse travels through the radar target between the Tx antenna and the Rx antenna. The method also includes determining a bodily parameter within the radar target as a function of the transmission and the reception of the first radar pulse and the second radar pulse.

Abstract: A bio-information acquiring device (1) that includes a measurement region setting unit (13) specifying, by image processing, regions respectively corresponding to at least two parts of a living body in frame images forming a moving image obtained by imaging the living body, a pulse wave calculation unit (14) detecting pulse waves in the at least two parts by referring to the specified regions, and a difference calculation unit (15) calculating a phase difference between the detected pulse waves in the at least two parts.

Abstract: An apparatus, such as a cardiac function management system can detect heart sounds following a sensed transition in physical activity level, such as from an elevated physical activity level to rest. A technique can include systems, methods, machine-readable media, or other techniques that can include identifying a physical activity level transition, receiving a heart sound signal, determining characteristics of the heart sound and subject physiologic activity to provide an indication, such as a heart failure status indication.

Abstract: Described herein is a guide wire that includes one, two or multiple pressure transducers for use in TAVI. The guide wire may include an aortic pressure sensor spaced from a left ventricular pressure sensor with sufficient length to allow the aortic pressure sensor to be located in the aorta while the ventricular pressure sensor is simultaneously located in the left ventricle. The pressure readings between the left ventricle and aorta may be subtracted to determine an improved indication of the prognosis of a patient with intermediate post-TAVR aortic regurgitation after assessment with transesophageal echocardiography.

Abstract: Electrocardiogram (ECG)-gated cardiac magnetic resonance imaging (MRI) alone may be unable to capture the hemodynamics associated with arrhythmic events. As a result, values such as ejection fraction are acquisition dependent. The desired RR-duration determines the arrhythmia rejection. By combining real-time volume measurements with ECG recordings, beat morphologies can be categorized and a more comprehensive evaluation of ventricular function during arrhythmia can be provided.

Abstract: The present invention discloses a physiological monitoring device, comprising: a physiological signal acquisition block in the form of a capacitive touch panel for detecting user's physiological signals; a micro-processor block for capturing capacitance change in accordance with the user's physiological signal and estimating user's physiological data; and an application program for controlling the operation of physiological monitoring device.

Abstract: A pressure transducer assembly including a mounting assembly including an electrical connector configured for selectable galvanic engagement with a pressure transducer and a medical sensor assembly including a pressure transducer, the pressure transducer including a flow pathway and a pressure sensor in pressure sensing communication with the flow pathway, the pressure sensor including a plurality of electrical contacts configured for direct galvanic engagement with the electrical connector only when the medical sensor assembly is mounted in operative engagement with the mounting assembly.

Abstract: A device for measuring blood pressure and for indicating the presence of atrial fibrillation, includes an inflatable cuff, a pump, at least one pressure sensor for measuring the pressure inside the cuff, a pressure relief valve for deflating the cuff, and a control unit for controlling the pump and the valve. A calculating unit determines the presence or absence of atrial fibrillation on the basis of pressure variation sensed by the sensor. The calculating unit is adapted to independently determine the presence of atrial fibrillation on the basis of at least one, preferably two sequences, of pulse beats. The control unit is configured to maintain the pressure in a predefined range or to restore the pressure to a predefined range for an additional sequence, and to determine the presence of atrial fibrillation only if the calculating unit determines the presence of atrial fibrillation during a first and/or preceding sequence.

Abstract: A system for recording, processing, and monitoring biosignals is provided, the system being configured to suspend data acquisition whenever an electric surgical tool or other generator of high frequency interference is in use. Such a system may protect the hardware of the system and reduce or eliminate the acquisition of distorted signals. The system of some embodiments includes an amplifier system configured to detect the presence of high frequency interference. Related methods are also disclosed.

Abstract: An endovascular device includes an elongate body having a proximal end and a distal end, an endovascular electrogram lead, a balloon, a processor and a memory. The endovascular electrogram lead and the balloon are on the distal end of the elongate body. The balloon is expandable from a fully stowed configuration to an expanded configuration. The processor receives and processes an endovascular electrogram signal from the endovascular electrogram lead. The memory stores instructions which, when executed by the processor, cause the processor to: determine one or more electrogram features based on the endovascular electrogram signal; determine a position of the elongate body within the vasculature of the patient based on the one or more electrogram features; and initiate expansion of the balloon to the expanded configuration based on the determined position of the elongate body within the vasculature of the patient.

Abstract: Provided is an atrial fibrillation detection system which can reduce the burden on a test subject, with which it is possible to detect even paroxysmal atrial fibrillation, and which can be used in the home, contributing to early detection of atrial fibrillation.

Abstract: An electrode apparatus for monitoring ECG includes: a sensing area consisting of graphite: a metal member which is attached to the rear surface of the graphite to transmit sensed information; a transmission line which is connected to the metal member and an ECG terminal in order to transmit the sensed information; a support member for supporting the metal member and the graphite; a silicon part of which the rear surface is coated with silicon; and an adhesive patch which has an adhesive material on the inner surface so that the electrode apparatus can be compressed and fixed to a user's skin.

Abstract: A biological information measurement device includes a photoplethysmographic sensor that detects a photoplethysmographic signal, an envelope detection processor that generates an envelope of the photoplethysmographic signal, and an amplitude normalization processor that normalizes amplitude of the photoplethysmographic signal to a desired amplitude value based on amplitude of the envelope. The device further includes an adaptive line spectrum enhancer that is capable of varying a filter coefficient, suppressing an aperiodic component contained in the normalized photoplethysmographic signal, and outputting a periodic component. A biological information obtainment unit is provided to obtain biological information such as a pulse rate based on an output signal from the adaptive line spectrum enhancer.

Abstract: Cardiac catheterization is performed with a catheter having a basket-shaped assembly at its distal end. A plurality of spline electrodes are disposed on the splines of the assembly. The assembly is configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body. A far-field electrode is disposed in the interior of the assembly. An intracardiac electrogram and a far-field electrogram are obtained with at least one of the spline electrodes and the far-field electrode, respectively. The far-field component is removed from the intracardiac electrogram using the far-field electrogram.

Abstract: A differential voltage measuring system is described. The differential voltage measuring system has a signal measuring circuit for measuring bioelectric signals, and an interference-signal measuring circuit coupled to the potential of the differential voltage measuring system and electrically connected to a fixed reference potential. In this case, the interference-signal measuring circuit is designed for measuring a current flowing from the potential of the differential voltage measuring system to the fixed reference potential. A differential voltage measuring system with an additional path is also described. Furthermore, a differential voltage measuring system with an averaging potential measuring method is described.

Abstract: A wearable device configured to acquire and process electrocardiographic measurements, detect lead inversion and correct the acquired measurements for lead inversion is provided. In one example, the wearable device can detect lead inversion by first assessing whether the P-wave of a given electrocardiographic measurement has a negative amplitude, and if the P-wave is found to be negative, the device can determine if the magnitude of the R-wave is smaller than the maximum of the magnitudes of the S-wave and the Q-wave. In another example, the device can be put through an enrollment procedure in which electrocardiographic measurements are taken with the device being worn at known locations on the body. Once the enrollment procedure is completed, when the device is being used, any electrocardiographic results obtained can be compared against the measurements taken during the enrollment phase, and the location of the device on the body can be determined.

Abstract: Techniques for determining paced cardiac depolarization waveform morphological templates are described. For example, an implantable medical device (IMD) may sense a cardiac electrogram of a heart, identify cardiac depolarizations within the cardiac electrogram, and determine that the cardiac depolarizations are paced cardiac depolarizations resulting from delivery of a pacing pulse to the heart by another IMD without detecting the pacing pulse and without communicating with the other IMD. The IMD may identify paced cardiac depolarization waveforms of the paced cardiac depolarizations, determine a paced cardiac depolarization waveform morphological template based on the identified paced cardiac depolarization waveforms, determine a normal cardiac depolarization waveform morphological template based on the paced cardiac depolarization waveform morphological template, and compare the normal cardiac depolarization waveform morphological template to subsequent cardiac depolarization waveforms.

Abstract: Aspects of the present disclosure are directed to detecting Atrial Fibrillation (AF). As may be implemented in accordance with one or more embodiments, a time series of inter-beat intervals is computed from a recording of activity of a beating heart. The time series is decomposed into subcomponents, and an envelope of at least one of the subcomponents is computed. The presence of atrial fibrillation (AF) is detected based upon characteristics of the envelope that are indicative of AF.

Abstract: Method for determining a parameter which is indicative for whether a patient is delirious or not, or is at risk of becoming delirious or not, wherein the method comprises the steps of: —providing electroencephalography (EEG) data comprising recording signals from at least two electrodes located on different locations on the patient's scalp during a predetermined time period, for instance at least 10 seconds, wherein at least one of the signals is recorded from the frontal half on the scalp; —processing said EEG data for obtaining a deviation signal from the two recording signals from the electrodes; —analyzing said deviation signal in the frequency spectrum for establishing slowing of said deviation signal and defining the parameter as the degree of slowing of said deviation signal which in combination with the locations of the recordings on the patient's scalp is indicative whether said patient is delirious or not, or is at risk of becoming delirious or not.

Abstract: Methods for mental treatments, such as treatments for mental disorders, are described. Such methods can include measuring user brainwaves while the user plays a video game, such as a video game where the user is exposed to a competitive environment. The user can be rewarded within the video game based upon brainwave measurements.

Abstract: A peripheral nervous system (PNS) neuromuscular disorder testing system incorporates a testing apparatus that is affixed to a patients skin, positioning a stimulus transducer (e.g., electrical contact(s), movable sharp point, etc.) into a nerve pathway of interest with an electrode and reference electrodes appropriately positioned relative thereto to measure the electrical signal produced. A wireless connection to a control box relays the data associated with the time of the stimulus and the sensed response to a diagnostic system that analyzes the waveform per selectable testing protocols with user tailorable view capabilities and data dissemination communication paths.

Abstract: A current perception threshold examination apparatus capable of realizing increased efficiency and reduction in a burden on an examinee is provided. In the current perception threshold examination apparatus that controls supply of a current from a power supply to electrodes of a catheter for diagnosis of interstitial cystitis, the current perception threshold examination apparatus has a direct current generating unit for generating a direct current on the basis of an instruction of a control unit, and a direct current resistance measuring unit that measures an electric resistance value of a diagnosis site on the basis of the direct current which is supplied to the electrodes.

Abstract: A system and method of tracking a flexible elongate instrument within a patient is disclosed herein. The system is configured to obtain remote localization measurement data of the flexible elongate instrument and obtain elongation measurement data of the flexible elongate instrument. This data is combined and transformed to a coordinate reference frame to produce a localization of the flexible elongate instrument that is more accurate than the remote localization measurements or elongation measurement data alone. The combined localization is then provided to a localization consumer.

Abstract: A device and method for a surgical navigation system comprising a connection unit, a marker carrier unit removably attached to the connection unit, an attachment unit connected to the connection unit for fixing the device to a body part of a patient. The connection unit comprises an articulated arm and the marker carrier unit comprises an attachment area for removably attaching the marker carrier element to the connection unit.

Abstract: The present invention involves a computer-based system and method for detecting and identifying implantable medical devices (“IMDs”) and/or retained foreign objects (“RFSOs”) from diagnostic medical images. In some embodiments, the system provides further identification—information on the particular IMD or RSFO that has been recognized. For example, the system may be configures to provide information feedback regarding the IMD, such as detailed manual information, safety alerts, recall, access to its structural integrity, and/or suggested courses of action in a specific clinical setting/troubleshooting. Embodiments are contemplated in which the system is configured to report possible 3D locations of RSFOs in the surgical field/images.

Abstract: A naso-oral device (10) for use in medical procedures such as endoscopy includes a bite block (12) and a gas manifold or nasal cannula (14) which are releasably engageable. When engaged, gas supplied to the gas manifold passes, in use, (a) towards a patient's nostrils, through openings (58) in the gas manifold; and (b) into the patient's mouth via a passageway (28) through the bite block. Exhaled air is sampled for CO2 monitoring via a coupling on the bite block and via nasal probes (74) on the gas manifold. The gas manifold can be detached from the bite block and still serve for both administering gas and sampling CO2 in exhaled air.

Abstract: The present disclosure provides portable capnography systems having multiple operational modes, with varying power consumption. Alternation between the operational modes may be conducted to reduce the overall power consumption of capnography systems. The power reduction may be advantageous in enabling capnography systems to be powered by mobile power sources.

Abstract: Device and method for assessing an asthma status of a subject including monitoring a breath related parameter of a subject suffering from asthma, comparing the breath related parameter to a baseline parameter of the subject; determining a deviation of the breath related parameter from the baseline parameter; obtaining an input parameter; and assessing the asthma status of the subject, based on an integrated analysis of the input parameter and of the deviation of the breath related parameter from the baseline parameter.

Abstract: A wearable respiration monitoring system and associated method that is configured to (i) determine three dimensional displacement of the spine of a subject with respect to the axial displacement of the subject's chest wall, (ii) process the three dimensional anatomical data, (iii) determine at least one respiration parameter associated with the monitored subject as a function of the three dimensional anatomical data, and (iv) generate at least one respiration parameter signal representing the respiration parameter.

Abstract: A touch sensor is configured to sense a contact event occurring between a body part of a user and the touch sensor. The touch sensor is configured to produce contact data in response to the sensed contact event. A processor is coupled to the touch sensor and memory. The processor is configured to store in the memory a sequence of data frames each comprising contact data associated with a different portion of the user's body part. The processor is further configured to generate biometric signature data using the sequence of data frames.

Abstract: A notification system that appropriately notifies a healthcare provider of a change in the state of a patient in a sickroom is provided. The notification system includes: a detection unit that generates movement information of a subject according to a change over time; a storage unit that is connected to the detection unit and stores the movement information; and a control unit that receives the movement information from the detection unit, analyzes the movement information, makes a determination on the occurrence of a predetermined event from the result of the analysis, specifies the movement information in a predetermined period including the time when the determination was made, applies a storage priority value to the movement information according to a type of the predetermined event occurred, and transmits the movement information to the storage unit.

Abstract: In aspects of the present disclosure, a no coding blood glucose monitoring unit including a calibration unit is integrated with one or more components of an analyte monitoring system to provide compatibility with in vitro test strip that do not require a calibration code is provided. Also disclosed are methods, systems, devices and kits for providing the same.

Abstract: Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.

Abstract: A reusable sensor is disclosed for producing a signal indicative of at least one physiological parameter of tissue. The sensor can include a sensor housing that has a distal opening, a wire lumen, and a proximal opening. The distal opening can include a lumen extending through the body of the sensor housing and the wire lumen can be located on the outside of the sensor housing. The sensor can also include a first component located on a top surface of the sensor housing and along the pathway of the wire lumen. The sensor can also include a second component located on the bottom surface of the sensor housing opposite of the first component. The second component can also be located along the pathway of the wire lumen. The sensor can also include a wire coaxially disposed within the wire lumen and connecting the first component and second component.