Abstract: A method of corneal transplantation with a cross-linked cornea is disclosed herein. In one or more embodiments, the method includes the steps of: (i) cross-linking a portion of a donor cornea so as to kill donor keratocytes in the donor cornea and make the cross-linked donor cornea less antigenic to an eye of a recipient patient; (ii) removing a scarred and/or diseased cornea or corneal portion from the eye of the recipient patient; and (iii) implanting the cross-linked donor cornea into the eye of the recipient patient in a location previously occupied by the scarred and/or diseased cornea or corneal portion, wherein the cross-linking of the donor cornea eliminates an immune response of the recipient patient to the transplanted donor cornea. Both penetrating keratoplasty transplant procedures and lamellar keratoplasty transplant procedures using a cross-linked donor cornea are disclosed herein.

Abstract: A method of photodisruptive laser surgery includes selecting a target region of a tissue for fragmentation, directing a beam of laser pulses to the selected target region of the tissue, and forming cells in the target region of the tissue by directing the laser beam to generate cell boundaries. The cells can be arranged in regular or irregular arrays. The cells can be generated in parallel or successively, with cell sizes and laser parameters which reduce the time of ophthalmic surgery considerably.

Abstract: Embodiments of the present invention encompass the manufacture of pre-cut lenses and the use of such lenses in combination with laser surgical techniques, including femtosecond laser photodisruption or photoalteration treatments. These techniques further expand the capabilities of lasers, and allow their use for both incising and refractively altering the eye. In many instances, embodiments disclosed herein are suitable for the treatment or correction of regular refractive errors and an irregular refractive alterations (such as correcting an irregular refractive error of the eye), without having to resort to two separate laser systems.

Abstract: Treatments to improve ocular conditions such as presbyopia are provided. Structural (mechanical) weakening of the sclera is accomplished through the formation of a 3-D pattern of laser foci in the sclera resulting in an increase in the range of ocular accommodation.

Abstract: An adjustable eyelid cover device and method for protecting a user's eyelids from being sunburned. The adjustable eyelid cover device and method includes an eyelid cover assembly including a pair of eyelid cover members being adapted to fit over a user's eyelids when a user has one's eyes closed; an elastic band adjustably interconnecting the eyelid cover members and being adapted to fasten about a user's head to position the eyelid cover members over the user's eyelids; and a size adjustment member engagable to at least a portion of the elastic band to adjust a size of the elastic band about the user's head.

Abstract: Disclosed herein are hemostatic fabrics that include agents, including metal fibers or powders, that can control bleeding and contribute to faster wound healing.

Abstract: Disclosed is a tampon applicator package assembly having a tampon applicator and a cap having a closed end and an open end. The tampon applicator has a barrel for housing a pledget and a plunger. The plunger has an end portion that is a cap cover that connects to a remainder of the plunger and mates with the cap at the open end to provide a seal with the cap that completely encloses the tampon applicator in the cap. Also disclosed is an assembly having a tampon applicator, a cap having both a closed end and open end, and a cap cover for covering the open end of the cap. When the cap cover is placed on the open end, the open end is sealed and the tampon applicator is completely enclosed in the cap.

Abstract: An absorbent article is provided that comprises a front waist region, a back waist region, a crotch region disposed between the front waist region and the back waist region, a front waist end edge, a back waist end edge, a longitudinal axis extending from a mid-point of the front waist end edge to a mid-point of the back waist end edge, a first longitudinally extending side edge, a second longitudinally extending side edge, an exterior surface, an interior surface, a topsheet, a backsheet, and an absorbent core disposed between the backsheet and the topsheet. A portion of the front waist region and a portion of the back waist region are joined in a surface to surface relationship to form a pant comprising a first permanent side edge seam and a laterally opposed second permanent side edge seam. The first and second permanent side edge seams define an initial waist opening circumference and a pair of leg openings.

Abstract: Disclosed herein is a pad coated with coffee which includes: an outer cover which comes into direct contact with the vagina of a woman; a coating layer which is formed below the outer cover and smells of coffee; an absorber which is laid below the coating layer to absorb secretions; and a waterproof outer cover which is laid below the absorber to prevent the secretions absorbed into the absorber from leaking out, wherein coffee powder is coated on the coating layer.

Abstract: An arm support for a personal mobility vehicle can include a first member having a first end that defines a first cavity, and a first attachment member that extends through the first cavity so as to define an axis. The arm support can further include a second member having a first end that is disposed within the first cavity such that the second member is pivotally attached to the first member by the first attachment member. The arm support can further include an actuator that extends through the first end of the second member and through the first cavity. The actuator can be operatively coupled to the second member such that actuation of the actuator causes the second member to pivot about the axis.

Abstract: A patient support apparatus includes a patient support structure, such as a bed frame or mattress or both, that is configured to support a patient in a recumbent position. The patient support structure is configured to provide at least one therapy to a patient. A therapy enabler token is coupleable to the patient support structure. The at least one therapy is disabled when the therapy enabler token is decoupled from the patient support structure and the at least one therapy is enabled in response to the therapy enabler token being coupled to the patient support structure.

Abstract: Apparatus and methods for providing therapeutic treatment for symptoms associated with GERD and/or other digestive disorders and/or other medical conditions are described herein. In some embodiments, an apparatus includes a base support and a support pillow member. The base support includes a support element portion and an encasement portion. The support element portion has a first end portion and a second end portion and a top surface disposed at an angle relative to a bottom surface of the support element. The second end portion has a height greater than the first end portion. The support element portion and the encasement portion collectively define an interior region. The support pillow member is disposable within the interior region. The support pillow member, the support element portion and the encasement portion collectively define a receiving portion configured to receive at least a portion of a user's arm and/or shoulder therein.

Abstract: A system for transferring an object from a first surface to a second surface that includes a housing dimensioned to span a distance between the first surface and the second surface, a first elongated roller positioned along a first edge of the housing, and a second elongated roller positioned along a second edge of the housing. A continuous belt is positioned in conveying relation with respect to the first roller and the second roller. A portion of the continuous belt conveys an object while another portion of the continuous belt passes through the housing. The continuous belt does not touch the first or second surface. A support structure having at least one portion positioned within the continuous belt is connected to a first end and a second end of the housing.

Abstract: An apparatus for automatically treating the excrement comprises a mounting unit, a control device unit, and a washing water supply path which is connected from the washing water supply part to the mounting unit. The washing water supply part comprises a washing water storage tank in which the washing water is stored. A pump is operated in a forward or in a reverse direction to supply the washing water of the washing water storage tank to the mounting unit, or collecting the residual washing water in the washing water supply path to the washing water storage tank. An instantaneous water heater provides on the washing water supply path to heat the washing water a control portion which controls the operations of the pump in the forward direction or the reverse direction.

Abstract: A casket includes a container configured to receive a deceased, the container including a bottom and sides defining at least a part of a casket interior. The casket further includes a lid disposed on the container to cover the casket interior. The lid is formed from a corrugated paperboard blank folded into a lid structure. The lid structure includes a top panel, at least two side panels and at least one end panel, and a plurality of supports extending to a height of the side panels. Each of the corner supports includes at least a first panel extending diagonally from a first location proximate one of the side panels to a second location proximate the at least one end panel. The first panel has a first length corresponding to the height of the side panels.

Abstract: A kit for assisting a disabled person in rehabilitation is disclosed herein. The kit includes a frame. The kit also includes at least one loop mounted on the frame. The loop defines a first opening. The kit also includes a flexible elongate member extending between first and second opposite ends. The flexible elongate member is selectively receivable in the at least one loop. The kit also includes first and second attachment members. The first and second attachment members can be connected at one of the first and second opposite ends of the flexible elongate member or at some point between the first and second opposite ends. Each of the first and second attachment members is operable to form an opening of variable size to receive and releasably tighten around a limb of the disabled person.

Abstract: A traction chair is disclosed which functions as a normal chair when not in use, but which can be deployed to provide a user with traction for decompressing the spine. The traction chair employs a stationary framework that is supported on the ground. A number of articulating components are mounted on the stationary framework; the articulating components being actuated by a motive force. The articulating components when actuated together cause the seat portion of the chair to separate from the backrest portion and open up a widening gap between the seat portion and backrest portion of the chair.

Abstract: A shoulder rotating apparatus assists a user in regaining strength and range of motion in the user's shoulder after shoulder injuries or surgery. The apparatus includes a base and a support plate. A support assembly couples the support plate to the base. A track extends into a bottom of the support plate. A ball is positionable within the track. A strap is coupled to the ball and is configured for securing to a hand of a user such that movement of the ball within the track facilitates movement of the shoulder and upper arm of the user when the user's hand is positioned within the strap.

Abstract: A wearable action-assist device includes a biosignal detection unit detecting a biosignal from a wearer, an action-assist wearing tool having a drive source supplying a torque acting on the wearer around each joint of the wearer as an axis of rotation, a control unit controlling the drive source to generate the torque according to the detected biosignal, a drive torque estimation unit estimating a drive torque generated by the drive source, a joint-angle detecting unit detecting an angular displacement of the joint, and a parameter identification unit identifying kinetics parameters concerned by substituting the estimated drive torque and the detected angular displacement into an equation of motion of an entire system including kinetics parameters intrinsic to the wearer. The control unit is configured to control the drive source according to a predetermined control method based on the equation of motion into which the identified parameters are substituted.

Abstract: A therapeutic walking trainer for improving the ability to walk, in particular for re-learning the ability to walk, with an upper frame, which has a torso-free body holder and provides forward support, and with a lower frame, which is connected to the upper frame by means of at least one supporting bar and has a number of rollers. To compensate for a torque acting on the vertical axis, the rollers are at least four in number, with at least one of the rollers, preferably exactly two of the rollers, being formed as drivable rollers. In addition, the invention relates to a combination of a therapeutic walking trainer with a motor-free treadmill, and the at least one supporting bar is connected to the lower frame via an elastic lower part.

Abstract: An electromagnetic massage device for bathtub or pool includes an integrated holder for being fixed in a mounting hole; a lock nut engaging a thread on a wall on the holder, that fastens the holder to the surface of the wall; a rubber case with a top portion that bulges outward and a bottom portion with a rim which fits to the base plate of the concave cavity of the holder to seal the opening of the upper end of the holder; a conductive coil provided in the ring cavity of the holder and encapsulated by an upper magnetic conductive cover, a lower magnetic conductive cover and a magnetic conductive shell; and a beating head and an armature fastened together and mounted in the guide cavity of the holder to slide in the guide cavity under the action of an electromagnetic field.

Abstract: Cohesive high-dosage strength micronized active ingredients may be dispersed in dry powder formulations for inhalation comprising carrier particles, by use of the apparatus described herein.

Abstract: Compliance calendars distributed in connection with prescription containers configured to improve compliance by a patient in taking a prescription medication, the compliance calendars configured to include a frequency reminder and one or more sequence reminders of the times to take the medicine during each frequency.

Abstract: The present disclosure describes a gastric jejunal tube having a gastric lumen and a jejunal lumen that run the length of the tube. The cross-sectional sizes of the lumens change from above to below the most distal gastric port. A method of making the gastric jejunal tube is also described.

Abstract: Provided are opaque materials exhibiting a good adhesive strength and a good color tone reproduction comparable with natural dental crowns as well as having a good operability. In addition, the opaque materials may exhibit a stain-resistance property in rebuilding-up a dental composition on the opaque materials in a cured form with a metal instrument. Further, the opaque materials may exhibit a good color tone reproduction comparable with natural dental crowns even if a dental membrane is thinly formed from the opaque metals. The dental membrane is formed from a first opaque layer and a second opaque layer, wherein the first opaque layer contains a filler of indefinite-shape particles and the second opaque layer contains a filler of spherical-shape particles, and wherein the first opaque layer is formed on a metal base and the second opaque layer is formed on the first opaque layer.

Abstract: The present invention relates to a solid composition comprising: a calcium silicate powder, a set accelerator in the form of a powder, a reinforcing filler in a solid form, a radio-opacifying agent in a solid form, at least one complementary ingredient selected from solid fibers or solid porous fillers, optionally a water-reducing agent in a solid form, and optionally solid pigments. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising in a first container a solid phase including the solid composition according to the invention, and in a second container an aqueous phase. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising a container, said container comprising at least two cells, the first cell comprising a solid phase including the solid composition of the invention and the second cell comprising an aqueous phase.

Abstract: A dental curable composition containing fluoroaluminosilicate glass particles (A), basic calcium phosphate particles (B1), acidic calcium phosphate particles (B2), a polyalkenic acid (C), tartaric acid (D), and water (E), wherein the dental curable composition contains 70 to 99 parts by weight of (A), 1 to 30 parts by weight in total of (B1) and (B2), 10 to 40 parts by weight of (C), 0.3 to 10 parts by weight of (D), and 10 to 90 parts by weight of (E) each relative to 100 parts by weight in total of (A), (B1), and (B2), and a Ca/P ratio of a sum of (B1) and (B2) is from 1.10 to 1.95. Accordingly, provided is a dental curable composition that is high in mechanical strength, particularly compressive strength, and excellent in remineralization capability.

Abstract: A dental adhesive composition has an adhesive component and an activator component. The adhesive composition has a volatile organic solvent component, one or more polymerizable (meth)acrylate compounds optionally containing fillers, and a polymerization photoinitiator. The adhesive component may also be a substantially homogeneous mixture of one or more polymerizable (meth)acrylate compounds and an effective amount of a photoinitiator, without a solvent. The activator component includes an aromatic sulfinate salt and an activator component solvent. A method for adhering a restorative to a dental surface includes preparing the surface for restoration; applying a mixture of an adhesive component and an activator component to the prepared cavity, thereby forming a coated cavity surface; and, applying a direct or indirect dental restorative to the coated cavity surface.

Abstract: A hygienic body wipe for an adult male. The body wipe comprises a non-woven fabric and a liquid composition that includes a body cleansing agent, a skin conditioning agent, a foaming agent, and water, and a pH of at least about 10.

Abstract: The invention provides the tools needed for a dental patient's caries risk assessment. Included is a complete turnkey system for caries risk assessment and treatment, including an ATP test and a plurality of rinses and educational and diagnostic materials. The system for the detection and treatment of the bacterial infection that causes dental caries in a patient comprises a disposable ATP Bioluminescence sampler to swab areas of the patient's mouth, a bioluminescent light meter which measures the amount of ATP present in the patient's mouth, a rapid culture test for the detection of Mutans streptococci and lactobacilli, a diagnostic testing component that includes a caries risk assessment questionnaire, a treatment component that includes a short term therapeutic oral rinse of at least two components, and a long term maintenance rinse.

Abstract: The invention relates to polyglycerol esters with a particular oligomer distribution of the polyglycerol present, and to their use in in particular cosmetic formulations as, for example, emulsifier.

Abstract: An aluminum salt composition comprising (a) an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, an OH:Al molar ratio of about 2:1 to about 2.6:1, exhibiting a Size Exclusion Chromatography (SEC) chromatogram having a SEC Peak 4 to Peak 3 intensity ratio of at least 7, and a Peak 4 intensity greater than a Peak 5 intensity in aqueous solution, and (b) at least one buffer chosen from an amino acid, glycine, and betaine, wherein a molar ratio of buffer to aluminum is about 0.1:1 to about 3:1.

Abstract: Disclosed herein are oral care compositions comprising a colorant blend comprising a triarylmethane green colorant and a naphthalene sulfonate yellow colorant in a weight ratio of from 2:1 to 1:2; and a substituted or unsubstituted phenyl alkene flavorant.

Abstract: A cleansing agent composition containing (A) a sulfonate-type surfactant and/or a sulfate-type anionic surfactant, and (B) a heterocyclic compound represented by the formula (1) wherein R1 and R2 are each independently a hydrogen atom, a methyl group, a hydroxymethyl group, or a hydroxyethyl group, shows high detergency and low irritativeness, can suppress rough skin after washing and drying, and can be preferably used for cosmetic agents.

Abstract: A chewing gum for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as a blend of hydroxyapatite crystals and sodium fluoride. The chewing gum can contain at least 20% of ascorbic acid without compromising the integrity of tooth enamel because hydroxyapatite will repair any damage to the enamel.

Abstract: A method for forming a large particle complex comprising the steps of combining a hydrolyzed corn starch polymer, a starch/cellulose polymer, a hydrogenated phospholipid, and gum arabic in a cosmetically acceptable carrier to form a premix composition; heating said premix to about 85° C. for about 15 minutes; and cooling the composition to room temperature. The particle complex is useful as a component of a sprayable composition which provides volumizing, hair fixing, and conditioning as a leave-on treatment for human hair.

Abstract: The present invention relates to a personal care composition with a synthetic random copolymer having a net positive charge, a detersive surfactant; and an aqueous carrier.

Abstract: Personal care products for maintaining fingernail and toenail appearance. In particular, nail polish compositions that have a formulation that is both safer and more environmentally-friendly to use. The present nail polish compositions comprise anionic polyester resins such as sodio-sulfonated polyesters and sodio-sulfonated co-polyester-co-polysiloxane copolymers as base resin vehicles.

Abstract: Dispersions of an encapsulated material by a polymeric membrane in a medium are disclosed. Such dispersions are useful in topical compositions including cosmetics and sunscreens.

Abstract: The embodied invention generally pertains to compositions, and the methods of making and using said compositions for promoting hair growth, slowing hair loss, and for preventing or minimizing hair loss that are effective and able to treat multiple aspects of the problem in one product and additionally is comprised of natural oils and minerals which greatly reduce the toxicities and side effect issues associated with present products. The compositions or formulations of the present invention relate to a hair loss solution that solves the problems associated with the loss, and damage of hair by working from the root to the surface of the scalp and to the hair shaft by treating a plurality of the causes and/or triggers associated with hair loss, or the prevention of hair re-growth.

Abstract: Compositions for promoting hair growth can be formed using food related oils. The food related oils include meadowfoam seed oil, neem oil, sesame oil, camelina, flaxeed oil, and tamanu oil. The oil can be combined with lime peel essential oil and/or aloe vera to create various products. The products in an oil for treating the hair and scalp, a treatment for damaged hair and scalp, shampoo, conditioner, pomade and hair root stimulant. A method for making each product is described. In addition, a method for using each product is described.

Abstract: The invention provides a method of preparing a suspension of microbubbles for use in a carrier liquid, wherein the microbubbles have a gas core and a liquid shell, said liquid shell comprising magnetic nanoparticles, and wherein the microbubbles satisfy the following conditions: (i) the force due to buoyancy (FBW) of the microbubble in the carrier liquid is greater than the weight (W) of the microbubble; (ii) the magnetic force (FM) on the microbubble due to a magnetic field applied to the carrier liquid is greater than the combined weight (W) and force due to buoyancy (FBW) of the microbubble; (iii) said magnetic force (FM) on the microbubble is greater than the force due to viscous drag (FD) on the microbubble due to flow of the carrier liquid; and (iv) the scattering cross section (?scat) of the microbubble to ultrasound allows the microbubble to be detectable and rupturable on exposure to ultrasound.

Abstract: Regimen for the treatment of rosacea include the application of an anti-redness composition to at least a portion of the cleansed area of skin afflicted with rosacea. The regimen may include the application of one or more of a polymetal complex, a composition containing metronidazole, and/or a protective composition. Kits containing components useful in performing such regimens are also described.

Abstract: Disclosed herein are parenteral solutions containing 7-halo-1,2,3,4-tetrahydro-3-aryl-6-quinazoline sulfonamide in N,N-dimethylacetamide, polyethylene glycol and D5W useful in the treatment of hypertension, heart failure and renal disease leading to edematous states. Also disclosed are methods for preparing such solutions.

Abstract: A method (and the resulting product) of making a medical implant device for releasing self-contained drugs on a controlled basis wherein the method utilizes, at least in part, computer-controlled 3-D printing equipment to deposit via nozzles portions of one or more layers of the medical implant product. The implant has an outer impervious coating, an inner matrix core, an opening and an optional bonding layer.

Abstract: The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of an antimicrobial compound, e.g., Dapivirine, to a human. The intravaginal rings of the invention address previous stability issues by utilizing a platinum catalyst (e.g., in the form of a platinum-siloxane complex) for the cross-linking reaction. The vaginal rings surprisingly achieve relatively high and steady release rates in vivo with a matrix ring containing a relatively small loading dose. While the matrix rings of the present invention have in vivo the steady release rates associated with reservoir rings, they are easier and less expensive to manufacture. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, and methods of preparing platinum-catalyzed intravaginal rings.

Abstract: Compositions and methods for treating glaucoma are provided. In particular hydrophilic ester prodrugs and their use to reduce central corneal thickening is provided.

Abstract: The present invention relates to solubility improving preparation for enhancing the oral absorption of a poorly soluble drug, which is comprising (A) and (B); (A) a granulated substance which comprises (i) a poorly soluble drug having an acidic group in the molecule, (ii) an alkaline agent, (iii) a surfactant, and this granulated substance dose not substantially contain a disintegrator, (B) a disintegrator existing only in the external of the granulated substance.

Abstract: Methods for the safe administration of imidazole or imidazolium compounds, and conditions that may be treated by these methods, are described herein.

Abstract: Disclosed herein is a microemulsifying system consisting essentially of coconut oil and Polysorbate 80 in a specific weight ratio. Also disclosed herein are microemulsion preconcentrates and microemulsions that contain a lipophilic functional ingredient formulated with the microemulsifying system. Processes for preparing the microemulsion preconcentrates and microemulsions are also disclosed herein.