Abstract: Apparatus is described for determining the optical quality of an optical element, the optical element having proximal and distal end portions. The apparatus also includes at least one non-polarizing beam splitter; at least one polarizing beam splitter; at least a first detector operatively associated with the at least one non-polarizing beam splitter; at least a second detector operatively associated with the at least one polarizing beam splitter.

Abstract: A optical microscopy vapor-condensation-assisted device comprises an air blowing device, a vapor producing device and a guide pipe connected with each other in seal. One end of the vapor producing device is connected to the air blowing device, another end of the vapor producing device is connected to the guide pipe. The vapor producing device produces vapor. The air blowing device blows air through the vapor producing device into the guide pipe.

Abstract: A device for optical coherence tomography (OCT) is provided. The device includes a light source for generating a sample beam incident on a matter and a reference beam for creating interference with the sample beam; a spatial light modulator enabling a plurality of ramp patterns for controlling an incident angle of the sample beam; and a diffraction grating for transmitting only a first diffraction component of the reference beam; whereby an image of the matter within a medium is captured by generating an interference image formed by the interference between the sample beam and the reference beam.

Abstract: A lighting device with expanded detection range includes a housing, which receives a seat to which a detector is mounted and has a circumference along which LEDs are mounted to mount therein, a lens being fit to an opening formed in a top of the housing corresponding to the seat so that a distal end of the lens is exposed outside the housing; a light shielding hood having a top end extending to the housing and connected to the lens and a bottom fixed to the seat to block entry of external lighting; and a reflector assembly including a reflector that condenses a signal source arranged on a top thereof and having inside and outside reflection surfaces and further including a fixing sleeve fixed to a bottom thereof to couple with the detector.

Abstract: The present invention relates to a kit comprising a DNA-dependant DNA polymerase and at least one natural deoxynucleoside and to a kit comprising a DNA-dependent DNA polymerase and a detection system comprising a DNA template molecule, a DNA primer molecule, and a fluorescent moiety capable of being displaced from, or bound to, dsDNA synthesized by said DNA-dependent polymerase.

Abstract: A fluorescent light detection device includes: an excitation light source; an excitation light fiber; a fluorescent light fiber; a detector configured to receive the fluorescent light emitted from the fluorescent light fiber; a retention member configured to retain the fibers so that an emitting end face of the excitation light fiber and an incident end face of the fluorescent light fiber are located at close proximity; an excitation light selection filter provided in contact with the emitting end face; and a fluorescent light selection filter provided in contact with the incident end face. The excitation light emitted from the emitting end face irradiates a test object via the excitation light selection filter and the fluorescent light produced by the test object is incident on the incident end face via the fluorescent light selection filter.

Abstract: The present invention relates to enrichment and/or identification of fetal cells of a maternal blood sample using fetal cell specific ligands and/or fetal cell specific hybridization probes wherein the ligand or probes are directed to an endothelial/mesenchymal marker, e.g. CD105, CD146 or CD141, in a first round of enrichment and the ligand or probes, in a second round of enrichment, are directed to an epithelial marker, e.g. a cytokeratin, such as CK7, CK8, CK18 or CK19. Enriched or identified fetal cells may be subjected to steps of detection or diagnosis, wherefore the present invention enables non-invasive 5 prenatal diagnostics.

Abstract: Chlorophyll fluorescence may be studied in response to a variety of environmental cues or conditions by growing phototrophic organisms under actinic illumination. Such illumination may be punctuated or disrupted to gain information about the photosynthetic properties or performance of the phototrophic organism. Instruments or devices for carrying out the method are also described.

Abstract: The present invention generally relates to emissive materials, devices, and related methods. In some cases, the present invention provides sensors and methods for the determination of analytes, wherein the analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material upon exposure to an analyte. The analyte and the emissive material may interact via a chemical reaction, such as an oxidative addition reaction, or other chemical, biochemical or biological interaction (e.g., recognition), to form a new emissive species. In some cases, the present invention may be useful in the detection of a wide variety of analytes, such as toxins, chemical warfare agents, and explosives. The present invention also provides emissive compounds, and related methods, including metal complexes that are capable of interacting with an analyte to produce a change in the emission of the compound.

Abstract: A method for the colorimetric detection of two compounds in a bulk sample comprises the steps of forming an aqueous solution of the bulk sample, inserting a single dip strip having a pair of test regions each having separate colorimetric indicator reagents for a different one of the two compounds to be tested for into the solution and then removing the dip strip from the solution, and observing the test regions for color changes denoting the presence of the two compounds. The methodology is especially adapted for the colorimetric detection of nitrates and chlorates, two components commonly associated with explosives and particularly homemade explosives.

Abstract: Systems and methods for imaging a plurality of blood fluid samples or other types of samples include processing at least a portion of a sample to enhance imageability of certain particles in that portion and subsequently imaging the sample portion. In some instances, processing and imaging of various samples may be staged in a manner to optimize throughput of the system or method.

Abstract: An optical module for surface inspection includes a first light source unit that illuminates a substrate with first light produced by a first light source and a first beam splitter that changes the path of the first light, a second light source unit that illuminates the substrate with second light polarized in a first direction, a direction of polarization changing unit that illuminates the substrate with the third light polarized in a second direction perpendicular to the first direction, and a detection unit that detects fourth light which is a product of the first light reflecting from the substrate, fifth light which is a product of the second light scattered from the substrate, and sixth light which is a product of the third light scattered from the substrate. The third light is produced by changing the direction of polarization of the second light reflected from the inspected substrate.

Abstract: A blade inspection apparatus inspects a plurality of blades periodically disposed on a periphery of a rotating shaft of a rotor of an engine and rotated on the rotating shaft. The blade inspection apparatus has a borescope having an insertion portion in which an observation optical system is provided, fixtures attached to one of a plurality of external access ports provided on the engine and fixing the borescope, and dedicated for each of the external access ports, and an identification information output portion for outputting identification information for identifying the external access port to which the fixtures are attached.

Abstract: An automatic optical inspection method for periodic patterns includes defining regular control points in a periodic pattern, forming aligned images surrounded by the control points, obtaining a median image and a deviation image from the aligned images and defining upper- and lower-limit images to form an adaptive model, using the adaptive model to compare each point of all aligned images, defining the point of the aligned image having a gray-scale pixel greater than the upper-limit image or the smaller than the lower-limit image as a defect area. The optical inspection method is applicable for the defect detection of various periodic patterns and users simply need to manually select a first reference point to a fifth reference point from the control points and further select a rectangular range of one of the control points to create an edge image to detect a defect of the periodic pattern.

Abstract: A method to detect a gas absorption line that includes alternately transmitting and sweeping two radio frequency (RF) signals through an absorption cell, wherein the two RF signals are transmitted at different frequencies separated by a range and are swept across a span of frequencies in a microwave and millimeter wave regions of a frequency spectrum. Receiving the RF signals by a receiver and analyzing the received signals by a closed loop system for relative absorption by a gas due to an absorption line of the gas in the span of the swept frequencies. Detecting the absorption line of the gas when the two RF signals straddle the gas absorption line and the relative absorption by the two RF signals is equal.

Abstract: A device designed to be used for neutron imaging, immersed in a medium containing specimens to be analyzed, comprises a first converter comprising a first material capable of converting thermal neutron radiation into remnant beta radiation and a second converter comprising a second material capable of converting a remnant beta radiation into light radiation, the second converter being in contact with the first converter. A method is also provided for neutron imaging immersed in a medium and using the device.

Abstract: The present application discloses methods and systems for scanning an object. The scanning system provides a first detector region having a thickness of at least 2 mm and a second detector region having a thickness of at least 5 mm. The second detector region is arranged to receive radiation that has passed through the first detector region. The method includes irradiating the object with radiation having having a peak energy of at least 1 MeV, and detecting the first profile radiation after it has interacted with or passed through the object in order to provide information relating to the object.

Abstract: A device for thermal analysis. This device includes at least one thermoanalytical measurement device and at least one infrared spectrometer, wherein the infrared spectrometer is fully integrated into the thermoanalytical measurement device. The thermoanalytical measurement device and the at least one infrared spectrometer are connected to one another by a lift-swivel unit. The at least one infrared spectrometer is disposed above the thermoanalytical measurement device.

Abstract: Disclosed is a method for determining when to replace a guard bed material used to remove one or more catalyst poisons from a feed based on a parameter change in a process. A guard bed having a guard bed material is in fluid communication with a catalyst bed having a catalyst. At least three monitors are positioned in said guard bed or said catalyst bed and at least one parameter of the guard bed or catalyst bed is monitored. A feed component comprising one or more catalyst poisons is supplied to said guard bed or said catalyst bed. The feed is contacted with said guard bed material or said catalyst to remove at least a portion of a catalyst poison and to form a product which produces an increase or a decrease in said parameter. The monitored parameters are compared to determine when to replace the guard bed material.

Abstract: A hard, transparent coating for a substrate and associated method for coating is disclosed. The coating includes alternating layers of a soft coating and a hard coating. The coating further includes a sensor. The electrical resistivity of the sensor may be measured to determine if the coating has been degraded. The coating may further include a hydrophobic outer layer.

Abstract: A method and apparatus qualifies a conductor for service and determines imbalance resistance of a conductor. The method and apparatus comprises feeding signals from a controller to termination ends of at least three wires of a conductor. In the controller a resistance difference is determined between first and second wires of the conductor using a measured resistance of one of the three conductor wires as a reference value. The conductor is qualified for services when the resistance difference between the first and second wires is below a threshold.

Abstract: A humidity determining device 20 includes first and second humidity determining sensors 17, 18 and a control unit 21. When the first and second humidity determining sensors 17, 18 react with a chemical substance, the humidity determining performance of the first humidity determining sensor 17 and the humidity determining performance of the second humidity determining sensor 18 change with time at different amounts of change. The control unit 21 computes a difference value between a first humidity value and a second humidity value determined by the first and second humidity determining sensors 17, 18. When the difference value is greater than a predetermined reference value, the control unit 21 outputs an anomaly signal indicating that the humidity determining performance of at least one of the first or second humidity determining sensors 17, 18 has been reduced.

Abstract: The present invention is a nanotechnology-based personal sensor device composed of molecularly imprinted polymers that are interrogated using radio frequency identification (RFID) technology for use in simultaneously monitoring airborne contaminants, e.g., of second-hand cigarette smoke.

Abstract: A method of using a sensor element includes: exposing a sensor element to an unknown analyte vapor; measuring a capacitance of the sensor element to obtain a measured capacitance; obtaining a true capacitance of the sensor element; exposing the semi-reflective conductive electrode to incident light and observing reflected light in order to measure a spectral change between the incident light and the reflected light; comparing the true capacitance and the measured spectral change, or at least one derivative thereof, to a reference library, the reference library comprising reference correlations between spectral change and true capacitance, or at least one derivative thereof, for a plurality of reference analyte vapors; and determining at least one of the chemical class or identity of the analyte vapor.

Abstract: A MEMS biochemical sensor configured to sense a target molecule, such as a DNA molecule, a protein molecule, and a viruses molecule. The biochemical sensor may include a cell and a readout module. The cell is configured to be coupled to a probe molecule, to retain a pre-sensing charge before the probe molecule is exposed to the target molecule, and to retain a sensing charge after the probe molecule is exposed to the target molecule. The readout module is coupled to the cell and configured to generate a measurement signal based on the pre-sensing charge and the sensing charge.

Abstract: A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution.

Abstract: An exhaust sensor comprises a sensing electrode and a reference electrode each in contact with an electrolyte. At least one of the sensing electrode and the reference electrode are formed by depositing an electrode precursor material on an electrolyte precursor material and sintering the combination at a sufficient temperature for a sufficient time to achieve densification of the electrolyte, wherein the electrode precursor material comprises an alkali salt. Electrode patterns having enhanced perimeter ratios are also disclosed. The resulting exhaust sensor is capable of providing a usable output at a reduced operating temperature.

Abstract: In order to compensate for variation in output of sensor elements 10, there is provided a compensating resistor 220 that has a resistance value reflected by correction information. The resistor 220 is connected in parallel with a VS cell 245 through paired electrode leads 236 and 237 and paired electrode pads 232 and 233. The paired electrode leads 236 and 237 are placed at a position electrically isolated from solid electrolyte substrates 120 and 140.

Abstract: Embodiments of the present disclosure relate to substance detection technology, and to signal extraction circuits and methods for ion mobility tubes, and ion mobility detectors, which can solve the problem with the conventional technologies that it is difficult to design and manufacture the leadout circuit for the pulsed voltage on the Faraday plates. A signal extraction circuit for an ion mobility tube includes an DC-blocking module configured to remove a DC voltage contained in a voltage extracted, by a signal leadin terminal, from the Faraday plate, and to output, by a signal leadout terminal, a pulsed voltage contained in the voltage extracted from the Faraday plate. An ion mobility detector includes the signal extraction circuit for an ion mobility tube according to the present invention.

Abstract: An ion mobility analyzer, combination device thereof, and ion mobility analysis method. The ion mobility analyzer comprises an electrode system that surrounds the analytical space and a power device that attaches to the electrode system an ion mobility electric potential field that moves along one space axis. During the process of analyzing mobility of ions to be measured, by always placing the ions to be measured in the moving ion mobility electric potential field, and keeping the movement direction of the ion mobility electric potential field consistent with the direction of the electric field on the ions to be measured within the ion mobility electric potential field, theoretically a mobility path of an infinite length can be formed so as to distinguish ions having mobility or ion cross sections that have very small differences.

Abstract: A sensor array comprising a series connection of parallel GMR sensor stripes provides a sensitive mechanism for detecting the presence of magnetized particles bonded to biological molecules that are affixed to a substrate. The adverse effect of hysteresis on the maintenance of a stable bias point for the magnetic moment of the sensor free layer is eliminated by a combination of biasing the sensor along its longitudinal direction rather than the usual transverse direction and by using the overcoat stress and magnetostriction of magnetic layers to create a compensatory transverse magnetic anisotropy. By making the spaces between the stripes narrower than the dimension of the magnetized particle and by making the width of the stripes equal to the dimension of the particle, the sensitivity of the sensor array is enhanced.

Abstract: A rolling search unit including an ultrasonic device and a heat exchanger mounted within a fluid-filled tire may be utilized to perform ultrasonic testing on an underlying railroad rail. The ultrasonic device may transmit or receive ultrasonic beams into or from the railroad rail, and the heat exchanger may be utilized to maintain the temperature of the fluid within the tire at a preferred level or within a preferred range. In such a manner, the results of testing obtained using the rolling search unit may be standardized regardless of the ambient temperature in the environment where the testing is being performed, and regardless of any heat gained or lost by the rolling search unit during operation.

Abstract: Ultrasonic bolt inspection apparatus and methods facilitate in situ as well as bench non-destructive evaluation (NDE) inspection of fastening bolt distal ends and their mating nuts. The apparatus is coupled to an exposed end of a fastener bolt head, its exposed thread tip or to a mating nut. The apparatus retains a phased array ultrasonic probe that generates inspection scan data and a rotational position encoder that generates rotational position data. The probe is coupled to an ultrasonic inspection system analyzer, which converts scan data into inspection data that characterizes possible defects in the inspected bolt. A system controller is coupled to the analyzer and the rotational position encoder, correlating rotation position data and inspection data, in order to identify location and characteristics of possible defects in the inspected bolt end.

Abstract: A fabrication process for producing, annealing, and conjugating nucleic acid molecules is implemented, under the direction of one or more computer programs, on two or more instruments, for carrying out the process. The process can include: (a) synthesizing, on a solid support and in a plurality of reactions, at least one of a nucleic acid and a peptide nucleic acid, and cleaving the synthesized biomolecule product from the support, providing a sample of synthesized biomolecule product from each reaction of the plurality; (b) measuring, for each sample, the volume of the sample and/or the concentration of the product; (c) subjecting the product from each reaction to chromatography under conditions suitable for achieving single-base-resolution for the product, the conditions being a function of the volume and/or concentration measured in (b); and then (d) collecting and pooling, from the chromatography of (c) for each sample, peaks that correspond to the product.

Abstract: One aspect of the invention provides a flow sensing apparatus including: a fluid channel that allows a fluid to flow in a first direction; a first temperature sensor arranged at a first position along the fluid channel; a second temperature sensor arranged at a second position along the fluid channel and separated from the first sensor by a predetermined distance along the fluid channel; a heating element arranged between the first and second thermoelectric sensors, the heating element being substantially equally spaced from the first and second thermoelectric sensors; a heating element temperature sensor for sensing a temperature of the heating element; and a control device configured to maintain the heating element at a substantially uniform temperature.

Abstract: Segments into which time is divided are set at a point where predicted elution time ranges of compounds in a compound table do not overlap. One or more compounds are allotted to each segment. Subsequently, the dwell time per ion is calculated in each segment, based on the number of assigned compounds, loop time and the like. If the dwell time is shorter than the lower limit value (No in S6), the one segment is forcedly subdivided such that each subdivision include a predetermined number of compounds (S7). A compound having an elution time range trespassing the new segment boundary is allotted as a measurement target to both segments across the boundary (S8). If the dwell time is of at least the lower limit in every segment regenerated by the subdivision (Yes in S9), the process for this segment is finished. Such subdivision and compound reassignment in every segment can automatically create a parameter table for a measurement method capable of achieving high quantitativeness.

Abstract: According to various embodiments, package evaluation systems and methods are provided for evaluating the sustainability of packaging used in the shipment of goods. In particular, the package evaluation systems and methods are configured for performing package evaluations and managing and providing access to data resulting from package evaluations. The package evaluations are designed to assess, among other things, the ability of sample packages to prevent damage to their contents, the volumetric efficiency of sample packages, and the sustainability of the materials used to construct sample packages. In addition, the systems and methods are further configured for assigning a certification to an entity associated with the evaluated packages based on the results of the evaluation.

Abstract: A method and apparatus for generating carbon monoxide and in particular a device for testing carbon monoxide detectors which utilizes the method and apparatus for generating carbon monoxide. A layer of Activated Carbon Cloth is heated so that it produces small quantities of carbon monoxide. The Activated Carbon Cloth may be provided in a removable cassette.

Abstract: The present invention relates to an apparatus and method of preparing a reference solution of a gaseous substance necessary for calibration of various measuring instruments used in measurement of the gaseous substance, such as radon (Rn-220) or a volatile substance, contained in seawater, subsurface water, surface water or the like. An apparatus of preparing a reference solution according to the present invention includes a gas component detector having two ports and configured to measure a concentration of a predetermined gaseous substance; a gas vessel having two ports and configured to accommodate the predetermined gaseous substance; a reference solution preparation vessel having two ports and configured to accommodate a predetermined liquid substance; pipe lines connecting the ports of the gas component detector, the gas vessel and the reference solution preparation vessel; and valves installed on the pipe lines.

Abstract: The present invention is directed to a processor-based analysis system and method. The technology includes a water analysis computer program, which may be an app for a smart device. Beneficially, an interactive visual display device is in communication with a sensing device. Advantageously, test parameter algorithms may be updated, and use of an auxiliary product with an intended test may be validated. Benefits further include improved accuracy of test results, user customization, and storage, management and output of associated data.

Abstract: The invention relates to methods for determining the source of hydrocarbons presented in the pores of a host rock or found in contaminated groundwater. The method includes the steps of (a) determining a first isotopic composition of boron and/or lithium in one or more components within a potential source rock sample, such as kerogen, clay, or water; (b) determining a second isotopic composition of boron and/or lithium in the hydrocarbons found within the pores of a host rock sample or in contaminated groundwater; and (c) comparing the first and second isotopic compositions to determine whether the potential source rock is the source of the hydrocarbons within the pores of the host rock or in contaminated groundwater.

Abstract: Apparatus for physically analyzing soil includes a sample changer for receiving at least two soil-sample holders, and having an element for placing each sample holder and sample thereof in a measurement area, in turns, according to a cycle repeated over time, the apparatus including: elements for measuring the size of the samples; elements for measuring the potential of the samples containing water; and elements for measuring the weight of the samples, wherein all of the measuring elements are grouped together in the measurement area so as to be simultaneously used implemented for a given sample when the latter is placed in the measurement area. The shrinkage curve and water potential curve, obtained from the measurements, represent the change, over time, in the status of the water and structure of the soil sample during the drying thereof, and can be used to determine the hydrostructural characteristics of the soil.

Abstract: A system and a method for determining the relative value of a naphtha stream is provided, by conducting analysis on the crude oil sample, after which modules or steps are performed to estimate the total liquid yields, estimate raw product yields, normalize raw product yields, determine the value of each fraction based on predetermined values, and calculate the total value of the naphtha stream. The method is repeated on samples from different crude oils in order to provide relative values for comparison purposes at a predetermined RON.

Abstract: A method for the production and/or processing of a web-shaped material, particularly paper, with at least one measuring system which records m measurement values yik per measurement position over at least a portion of the width s of the web-shaped material at n different measurement positions within a fixed time interval ?t. The method is characterized in that the method includes determining a rational quality number Q, the value of which for a quality of the web-shaped material that is considered acceptable lies within an acceptance range which is to be empirically determined for the production process and which has a lower limit U and an upper limit O, where U and O are in each case rational numbers.

Abstract: A multi-function testing apparatus contains a test cell, a piston positioned within the test cell and an adjustable piston depth-setting rod. The testing apparatus may be used to assess carbon dioxide resistance and hydraulic bonding strength of a set cement as well as to evaluate the self-healing capabilities of a set cement. Testing on the set cement may be conducted at simulated downhole conditions.

Abstract: A sensing device includes a shell comprising an elastomeric material, the shell including a first portion having a first end and a second portion having a second end. The shell may be egg-shaped. The first portion includes a conducting disc and a plate that includes a temperature sensor, a location sensor, and a micro-fiber composite sensor. The first portion also includes an antenna and a first electrode extending through a first hole in the first portion of the shell. The second portion includes a quantity of a metallic substance embedded on the inside surface of an end of the second portion, and a second electrode extending through a second hole in the second portion of the shell. The sensing device may be inserted into a concrete mixture, obtain measurements relating to the concrete mixture, and transmit data to a database.

Abstract: A cell grabber has a unitary structure including a transparent grabber head at a terminus thereof and an elongated mounting portion extending therefrom for attachment to a force transducer. The grabber head has a planar or concave bonding surface which is coated with an adhesive film to secure the specimen, especially single cells, for tensile measurements. The cell grabber may be used in connection with auxotonic, isometric or isotonic force measurement systems.

Abstract: Methods, systems, and compounds for detecting modified nucleic acid bases are disclosed and described. The methods provide for detecting a nucleic acid lesion and can include directing a nucleic acid adduct into a channel, wherein the nucleic acid adduct includes a nucleic acid having a lesion and a current modulating compound coupled to the nucleic acid at the lesion (110), and measuring a change in current through the channel in response to the current modulating compound to detect the lesion (112). The method can optionally include forming the nucleic acid adduct. Also provided is a method for identifying the number of repeat nucleotides in at least a portion of a nucleic acid strand, a method of assigning a registration marker within a nucleic acid, and a method of obtaining sequence information from a nucleic acid comprising assigning a registration marker on the nucleic acid.

Abstract: The present invention provides a method for determining at least one evaluation parameter of a blood sample, comprising the following steps: providing (S4) at least one blood gas parameter; providing (S5) at least one hemostasis parameter; and determining (S6 . . . S10?) the at least one evaluation parameter as a function of the blood gas parameter and/or the hemostasis parameter.

Abstract: Activated clotting time (ACT) tests detect blood clotting time based on the viscosity changes of a test sample, using a ferromagnetic washer lifted to the top of a test chamber and then dropped from the top via gravity; a drop time greater than a preset threshold value indicates clotting of the test sample. Blood samples which have high levels of heparin usually produce very weak clots that may easily be destroyed by the lifting movement of the washer. But if the clot threshold is set low to detect the weak clots, false detections occur during early testing cycles when activators are not fully suspended during the mixing cycle. Improved algorithms for lifting the washer and adjusting over time enable accurate detection of weak clots.