Abstract: The present disclosure relates to compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of preparing compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of using the bone compositions, bone implants and variants thereof.

Abstract: The present invention can be used for actual implantation surgery without a scaffold. The present invention provides a synthetic tissue or complex which can be produced by culture and has a high level of differentiation ability. The present invention also provides a therapy and medicament for repairing and/or regenerating tissue using replacement and covering. By culturing cells under specific culture conditions such that medium contains an extracellular matrix synthesis promoting agent, the cells are organized and are easily detached from a culture dish. The present invention was achieved by finding such a phenomenon. In addition, the self contraction of the tissue can be regulated by culturing the tissue in a suspended manner. Therefore, it is possible to regulate the three-dimensional shape of the tissue.

Abstract: Methods of providing dose controlled application of bone graft materials are disclosed. In particular, methods for determining a target quantity of bone graft material for clinical application in order to ensure maximum clinical results are provided. These methods comprise determining the target weight of the material to be applied.

Abstract: A method for using 3D printing technology produces personalized biomimetic drug-eluting coronary stent and the product thereof. The process of manufacturing stent, based on coronary angiography imaging data, measures the diameter of diseased coronary and conducts 3D reconstruction. A personalized stent for each patient according to diameter, length, and morphological characteristics of target vessel that suited to the lesion is produced. The coronary stent is formed from biodegradable poly-L-lactic acid (PLLA) or other materials. The stent is modeled by 3D printing and then coated with polymers carrying antiproliferative drug to reduce restenosis (the polymers is a mixture of antiproliferative drug and PDLLA at a ratio of 1:1).

Abstract: A drug delivery device, method of making a drug delivery device, and method of using a drug delivery device are described. The drug delivery device may be used to treat a target area within a patient's vasculature and comprises a shell, agent, port, and an optional seal. The agent may be any number of compounds, including but not limited to a therapeutic, anti-cancer compound.

Abstract: Disclosed is a system for the collection, processing and reuse of amniotic fluid and placental aspirate at a C-section site. The system includes a canister positioned along the vacuum line through which the amniotic fluid and placental aspirate is suctioned. The canister has a coil whereby the heavier cellular components, including stem cells, platelets and growth factors, are separated coincident with the surgical procedure. The canister has a port whereby the heavier cellular material can be removed from the canister. The heavier cellular material can be then applied to the wound site of the cesarean section patient. The system disclosed allows for the processing of the amniotic fluid and placental aspirate to take place in the same room as the surgical procedure. A kit and method are also provided.

Abstract: A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance includes an impermeable flexible overlay for applying a reduced pressure to the covered portion of the wound. The wound treatment appliance may also include a vacuum system to supply reduced pressure to the wound in the area under the flexible overlay, a wound packing means to prevent overgrowth of the wound or to encourage growth of the wound tissue into an absorbable matrix including the wound packing means, a suction drain, a collection chamber to collect and store exudate from the wound, and/or a suction bulb which may be used to provide a source of reduced pressure to an impermeable overlay that covers all or a portion of the wound. Finally, methods are provided for using various embodiments of the wound treatment appliance.

Abstract: Systems and methods are presented for providing reduced pressure to and monitoring pressure at a plurality of tissue sites using a plurality of pressure management devices. The pressure management devices are associated with a plurality of sensing conduits that fluidly couple the pressure management devices and the plurality of tissue sites. Other systems, methods, and devices are disclosed.

Abstract: The disclosure herein provides system, methods, and devices for collection of fluids, for example, bodily fluid and other fluids. An aspiration and fluid collection device for collecting bodily fluid and other fluids comprises a cap which may be mounted on a compressible resilient body comprising a cavity for storage of collected bodily fluid and other fluids. The cap comprises an inlet port comprising a first one-way valve positioned to enable bodily fluid and other fluids to flow into the cavity through the inlet port, but not out of the cavity through the inlet port; and an outlet port comprising a gas permeable but liquid resistant membrane positioned to enable gas to be expelled from the cavity through the outlet port, but to resist bodily fluid and other fluids being expelled from the cavity through the outlet port. The outlet port further comprises a second one-way valve positioned to enable gas to be expelled from the cavity through the outlet port, but not into the cavity through the outlet port.

Abstract: A reduced pressure treatment system includes a control unit having a control system and a reduced pressure source. The reduced pressure treatment system further includes a manifold unit in fluid communication with the reduced pressure source and a component module to augment treatment. The component module is configured to communicate with the control system of the control unit, and the component module includes a first mounting region configured to be coupled to a complimentary mounting region of the control unit. The component module further includes a second mounting region identical to the complimentary mounting region of the control unit to allow a second component module to be coupled to the first component module.

Abstract: The invention relates to a breast pump kit comprising a breast pump collection system which is to be replaceable and detachable connected to an electrical driving unit during use. The breast pump collection system comprises a breast shield for placing on a breast of a user, a pump unit, and tubing connecting the breast shield to the pump unit. The pump unit comprises a compartment of a variable volume in fluid connection to the exterior only via the tubing. The pump unit is configured to be detachable combined to the driving unit such that a driving motion of the driving unit acts to alternatingly expand and contract the compartment of the pump unit. In this way the pump unit creates alternating suction and pressure in the breast shield and at the breast of the user when in use. The invention further relates to a breast pump collection system for use in such breast pump kit.

Abstract: The present disclosure provides advantageous breastfeeding devices and/or assemblies. More particularly, the present disclosure provides advantageous vacuum assisted breastfeeding devices/assemblies, and related methods of use. The present disclosure provides assemblies/devices to assist mothers in breastfeeding infants. The advantageous assemblies/devices of the present disclosure can provide feeding assistance and improved breastfeeding rates to infants (e.g., premature infants) while they are being held close to the mother and feeding. Premature infants, and full-term infants with developmental delays, transient breastfeeding problems, and or cleft lip and palate can get several benefits from the assemblies/devices of the present disclosure.

Abstract: A total artificial heart for a mammalian cardiovascular system is provided. The total artificial heart has a pump casing including an outer housing and an integral hollow support shaft extending therethrough. The casing defines a first flow path within the outer housing about an exterior of the hollow support shaft and a separate second flow path extending within the hollow support shaft. An annular impeller is housed within the outer housing of the casing for rotation about the hollow support shaft to provide a centrifugal flow pump in the first flow path, and an axial flow impeller is housed within the hollow support shaft of the casing for forming an axial flow pump in the second flow path.

Abstract: The invention relates to a flexible catheter (1) with a drive shaft (2), with a sleeve (6) surrounding the drive shaft (2) and with a sheath (7) surrounding the drive shaft (2) and the sleeve (6), wherein the drive shaft, the sleeve (6) and the sheath (7) are pliable, wherein the drive shaft (2) at a proximal end of the drive shaft (2) comprises a coupling element (5) for connecting the drive shaft (2) to a drive motor (18), wherein the drive shaft (2) at least regionally consist of a alloy which contains at least 10% by weight of chromium, nickel and cobalt in each case. The invention moreover relates to a blood pump arrangement with such a catheter.

Abstract: A syringe adapter for holding various sizes of syringes. A syringe includes a tip, a barrel, a plunger, a flange, and a syringe axis extending from the tip to the plunger. An example syringe holder attaches to a fluid delivery system and includes a syringe clamp. The syringe holder holds a syringe stationary in the syringe clamp. The syringe clamp is offset from the fluid delivery system such that the syringe, or connections to the syringe, does not interfere with other components of the fluid delivery system. The syringe holder may include a support bar, which the syringe clamp can slide along. Alternatively, the syringe clamp may be rotatable.

Abstract: Aspects of the present disclosure provide systems, devices, and methods for delivering substances such as fluids, solutions, medications, and drugs to patients using infusion devices having a set of advanced features. These advanced features include aspects related to the programming of infusion devices, the configuration of infusion sequences performed by the infusion devices, and the interconnection of multiple infusion devices for interoperation during an infusion having a sequence of infusion steps.

Abstract: A belt clip assembly is disclosed. The belt clip assembly includes a device retainer having a first retainer defined to retain a clip pin. The belt clip assembly further includes a clip coupled to the device retainer via the clip pin and the clip includes a detent and the clip is further defined to retain a tab pin. A tab is coupled to the clip via the tab pin, the tab being rotatable about the tab pin. Wherein the device retainer is initially rotatable about the clip pin independent of rotation of the tab about the tab pin. Additionally, the rotation of the device retainer about the clip pin results in a finite displacement of the device retainer.

Abstract: The present invention relates to an injection device for endoscopy, and provides: a feature of inserting a needle for endoscopy into a tissue, in a state of holding a body tissue, which is a region to receive an injection, and then injecting an injection solution thereinto; and a feature enabling stanching of the bleeding region if bleeding occurs. That is, tissue is held by holding forceps and a needle is inserted thereinto, corresponding to a series of operations from a state in which the needle is accommodated between the holding forceps for holding the tissue, and then an injection solution is injected into the tissue through the needle. In addition, a bleeding region is stanched by the heat transferred to the holding forceps without using a separate hemostat if bleeding occurs during the operation.

Abstract: Provided is a precision variable flow rate infusion system and method for delivering a liquid from a reservoir having an initial potential outflow rate to a patient. The system includes at least a first flexible flow rate tubing having a pre-defined flow rate selected at a maximum dosage flow rate for the liquid from the reservoir, the pre-defined flow rate being less than the initial potential outflow rate of the reservoir. Also provided is an adjustable flow rate controller having an inlet and an outlet, at least one internal fluid pathway there between and a fluid pathway modifier structured and arranged to modify the internal fluid pathway from the inlet to the outlet from a closed pathway to a maximum flow pathway with a plurality of different flow rate pathways there between.

Abstract: An endovascular microvalve device for use in a vessel during a therapy procedure includes an outer catheter, an inner catheter displaceable within the outer catheter, and a filter valve coupled to the distal ends of the inner and outer catheters. The valve is constructed of a braid of elongate first filaments coupled together at their proximal ends in a manner that the first filaments are movable relative to each other along their lengths. A filter is provided to the braid formed by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments. The lumen of the inner catheter delivers a therapeutic agent beyond the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ.

Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

Abstract: The present invention relates to a compensation device for setting a flow rate of an infusion solution, a device for automatically controlling the flow rate of the infusion solution, and a method for controlling an optimal target flow rate using a flow rate coefficient of a flow rate controller, the compensation device adjusting a display scale of an infusion solution flow rate controller corresponding to a target flow rate on the basis of a one-time actually measured flow rate in setting the target flow rate by controlling an infusion solution flow rate controller of an infusion solution.

Abstract: An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.

Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

Abstract: The invention provides a drug delivery device adapted to receive a cartridge, the cartridge being adapted to receive a needle assembly. The drug delivery device comprises a front-loaded cartridge holder adapted to receive and hold a cartridge in a mounted state and being actuatable between an open loading state and a closed operational state. The drug delivery device is further provided with blocking means configured to prevent the cartridge holder from being actuated between the closed and the open state when a cartridge with a mounted needle assembly is held in a mounted position.

Abstract: Embodiments disclosed herein relate to systems and methods for transferring fluids. A fluid pathway can extend between a first fluid container and a second fluid container. An air chamber can be in fluid communication with the fluid pathway between the first fluid container and the second fluid container. During normal operating pressures, air can be maintained in the air chamber. During low pressure conditions (e.g., caused by a malfunction), the air in the air chamber can expand to a sensing location (e.g., in the fluid pathway). An air sensor can detect the presence of the air at the sensing location, and can provide an indication of a possible low pressure condition.

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Abstract: A permeation apparatus comprises an aspiration tube; an injection tube; and a water-absorbing cover member for covering at least a distal end of the injection tube and a vicinity of the distal end. The aspiration tube is configured to aspirate a fluid flowing from the water-absorbing cover member into the aspiration tube.

Abstract: The present relates to a filter needle coupled between a fixation member having a needle for injecting a medical fluid after filtering foreign substances contained in the medical fluid and a disposable syringe, the filter needle includes an outer housing having a front end portion to which the fixation member is coupled and a rear end portion to which the disposable syringe is coupled and a filtering unit which is disposed inside the outer housing, and in which a medical fluid supplied from the fixation member to the disposable syringe is passed through as is, while a medical fluid supplied from the disposable syringe to the fixation member is filtered.

Abstract: The disclosure refers to a skin piercing tool for locally piercing human or animal skin, comprising a proximal tool section; a distal tool section, in which a piercing tip is arranged; one or more needles, in which a needle shaft is provided in the area of the proximal tool sections and a needle tip is provided in the area of the distal tool section as part of the piercing tip; and a supply reservoir that extends as an open reservoir between opposing needle sections of the one or more needles and extends toward the proximal tool section behind the piercing tip, wherein the supply reservoir is in fluid communication with the piercing tip.

Abstract: A dosage inhaler includes an active liquid container, which contains a liquid having an active ingredient dissolved therein, and an atomizer by which the liquid is transformed into an aerosol and can be introduced into an aerosol dome, in which there is a baffle plate and to which an inlet tube and an outlet tube are attached, and an electronic control. The atomizer can be intermittently operated by a user and the user command readout is visible to the user. The generation of the amount of aerosol inside, and below, the aerosol dome is able to be separated in time from its eventual inhalation by the user.

Abstract: A mobile dressing for delivering pressurized therapy gas to a wound. The dressing may include an inflatable structure for creating a sealed cavity around the wound. The inflatable structure further may include a dimple and an aperture within the dimple. A first lumen may be fluidly connected to the aperture for delivering pressurized therapy gas to the dimple. A second lumen may be fluidly connected to the opening for delivering pressurized gas to the inflatable structure. A first pump may include a first intake port fluidly connected to a first reservoir of therapy gas, as well as a first discharge port fluidly connected to the first lumen for supplying therapy gas at an increased pressure. A second pump may pressurize air for inflating the inflatable structure and creating a sealed cavity over the wound. Pressurized therapy gas may be administered to the wound in the sealed cavity.

Abstract: Systems and methods are described for monitoring usage of a medicament dispenser—particularly an inhaled medicament dispenser. While operating in a low-power mode, a first sensor is monitored for a signal indicative of handling of the medicament dispenser by a user. In response to detecting such handling, the device exits the low-power mode and begins to monitor a second sensor for a signal indicative of dispensing of the medicament. The usage monitoring device can be embodied as an attachment configured to be selectively coupled to one of a variety of different inhalers including, for example, a Diskus-type inhaler and a Respimat-type inhaler.

Abstract: Described herein are interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The devices can be used in a wired or wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system, to evaluate the performance of the inhalation system and/or to detect the characteristics profile of a dry powder formulation emitted from the inhalation system in use.

Abstract: A device for delivering medications with hydroflouroalkane propellant driven metered-dose inhalers (MDIs). The device includes a collapsible bag to which is attached a bidirectional mouthpiece and an adaptor that receives the MDI. The mouthpiece contains a reed that functions as an audible signal and a screen to prevent inhalation of unwanted particles. When the MDI is triggered it discharges the medication into the collapsible bag which is then inhaled by the user through the mouthpiece. This collapses the bag. The reed emits an audible sound if the user inhales above a predetermined flow rate to maximize medication delivery and ensure dose-to-dose consistency.

Abstract: A breathing assistance apparatus user interface is described that presents operational modes, warnings, user instructions, fault conditions, status, menu options, hidden options, screens, panels and the like.

Abstract: This disclosure describes systems and methods for managing a move of a patient being monitored or treated by a medical system, such as a medical ventilator. The disclosure describes a novel approach for preventing a patient from being moved from a first location to second different location that is connected to a monitoring and/or treatment system, before all of the necessary hoses have been disconnected from the patient. Further, the disclosure describes a novel approach of ensuring that all of the necessary hoses are reconnected to a patient being monitored or treated by a monitoring and/or treatment system after being moved from the first location to the second different location.

Abstract: Automated methods provide hypopnea detection for determining a hypopnea event and/or a severity of a hypopnea event. In some embodiments, a calculated short-term variance of a measured respiratory flow signal are compared to first and second proportions of a calculated long-term variance of the measured flow signal. A detection of the hypopnea may be indicated if the first measure falls below and does not exceed a range of the first and second proportions during a first time period. In some embodiments, a hypopnea severity measure is determined by automated measuring of an area bounded by first and second crossings of a short-term measure of ventilation and a proportion of a long-term measure. The detection methodologies may be implemented for data analysis by a specific purpose computer, a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected hypopneas.

Abstract: A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths.

Abstract: Systems, devices and methods for selectively blocking respiratory air flow to portions of a lung are disclosed. For example, one bronchus of a lung may be sealed off while another bronchus remains open to air flow. An endobronchial blocker may comprise an at least substantially transparent elongate member configured to facilitate real-time monitoring of the position of an inflatable member of the endobronchial blocker throughout a surgical procedure using a visualization or imaging device inserted within a main lumen of the endobronchial blocker.

Abstract: A protective cover for use with a tracheostomy tube inserted into a patient's trachea comprises a middle portion including an opening for a tracheostomy tube to pass through, a first strap portion extending from the middle portion in a first direction, and a second strap portion extending from the middle portion in a second direction opposite to the first strap portion. The cover's middle portion and strap portions cover and substantially prevent secretions from reaching underlying equipment such as a trach tie and a neck plate used to secure the tracheostomy tube to the patient, while allowing the tracheostomy tube to be used for breathing.

Abstract: An airway device is provided for opening a patient's airway. In an embodiment, the airway device provides dual tubes which allow the patient to breathe on his/her own, to be ventilated, or to be intubated. The airway device includes a camera which provides constant visualization of the patient's tissues during insertion of the airway device and during the entire medical procedure. in some embodiments, the airway device includes an endotracheal tube. A transmission lumen monitors heart and breath sounds. Information from the camera and the transmission lumen is relayed to a microprocessor to allow for monitoring which may be remote.

Abstract: A breathing protector to be fitted in a tracheostoma is disclosed. The breathing protector comprises a housing with a distal part and a proximal part, a first opening at a distal end of the distal part, and a second opening at the proximal end of the breathing protector. A valve flap is arranged at the first opening to closingly engage with a valve seat circumferentially of the first opening. The valve flap and the valve seat create a main valve being in an open position during inhalation and in a closed position during normal vegetative exhalation through the breathing protector. A spring member spring biasing the distal part in relation to the proximal part is comprised in the breathing protector to create a relief valve, being in a closed position during normal vegetative exhalation and transiting into an open position when the pressure in the trachea and thus the breathing protector exceeds a threshold value corresponding to a discomforting high pressure in the trachea.

Abstract: Tracheal tube systems may include first and second tubes and an inflatable balloon. The first tube may be flexible and hollow and have first and second open ends. The inflatable balloon may be affixed to and circumferentially surround a portion of the first tube. The inflatable balloon may include an indentation sized and positioned to accommodate a portion of a second tube positioned therein, when the inflatable balloon is inflated. The second tube may be hollow and have a multiplicity of holes along a sidewall not in contact with the balloon. The second tube may be configured to be coupled to a suction device that creates a negative pressure in the second tube. When the tracheal tube system is inserted in a patient's trachea, the negative pressure in the second tube may act to remove, or suction out, fluids and other matter from the trachea.

Abstract: A method of opening an airway of a patient by a medical professional in a medical procedure using an airway device is provided. The airway device includes a ventilating tube and an intubating tube, and a camera lumen attached to one of the tubes. A camera is inserted into the camera lumen, and the camera provides visual information to the medical professional about the tissues of the patient during the medical procedure. The airway device is inserted into the throat of the patient and positioned proximally of the vocal folds under visual monitoring by use of the camera. The camera provides constant visualization of the patient's tissues during insertion of the airway device and during the entire medical procedure.

Abstract: Featured herein is a surgical airway device (10) that is constructed and arranged to be placed into the mouth of a patient to maintain a surgical airway in the patient. Also featured is a method of using such a surgical airway device (10). The surgical airway device (10) has a flange (20) that is constructed and arranged to be located outside of the mouth, an inner tube (21) that defines a working channel (22) defining an anterior opening in the flange (20) and located proximate the lips, and a posterior end (26) located in the back of the mouth. There is an outer tube (70) that is generally coaxial with, spaced from and fully or partially surrounds the inner tube (21), wherein a coaxial gap (80) is located between at least part of the outer tube (70) and the inner tube (21). There is a first lumen (30) that is in fluid communication with the working channel (22) and a second lumen (40) that is in fluid communication with the coaxial gap (80).

Abstract: Breathing assistance apparatus for treating sleep apnoea are described. More specifically, nasal interface for the supply of respiratory gases, but most particularly positive pressure gases are described. The nasal interfaces may include various forms of nasal pillows or nasal plugs. Associated elements such as manifolds or housings to hold or secure the pillows or plugs, or headgear are also disclosed.

Abstract: An expandable tubing system for delivering gases delivers various gases to patients. The system includes at least one expandable tube and a nasal cannula. The expandable tube includes a main tube which delivers gases from a gas supply to the nasal cannula or another device. The at least one expandable tube each include a first coupler, a second coupler, an inner tube, and an outer cover. The first coupler and the second coupler allow the inner tube to be connected in between two devices. The inner tube expands when filled with gases and retracts when emptied. The outer cover encircles and protects the inner tube. The nasal cannula includes a cannula coupler, a cannula tube, and a nosepiece. The cannula coupler connects the nasal cannula to the main tube. The cannula tube is transports gases from the cannula coupler to the nosepiece, which directs gases into the patient's nose.

Abstract: A manufactured component, such as headgear or a headgear strap, for a patient interface for delivery of a supply of pressurised air or breathable gas to an entrance of a patient's airways may include a textile portion having a first material with a first melting point. It may also include a plastic portion over-moulded to the textile portion. The plastic portion may be formed of a second material having a second melting point. The melting points may be different such that the second melting point is chosen to be less than the first melting point of the first material. The component may be moulded in a multi-step process that moulds separate portions of the plastic portion and the textile portion at different times. The resulting plastic portion may then have a mechanical bond with the textile and may do so without significant chemical bonding between the plastic portion and the textile.

Abstract: The present invention relates to oxygen sensors for medical ventilators. A medical ventilator includes a patient circuit delivering inspiratory airflow to a patient and returning expiratory airflow from the patient back to the ventilator. A manifold includes an air flow path into the patient circuit, and a port with an opening for an oxygen sensor. When mated to the port, the oxygen sensor samples the air in the air flow path and detects the amount of oxygen in the air. When the oxygen sensor is inserted into the port, a valve is biased open, to allow airflow through the opening into the oxygen sensor during ventilation. When the oxygen sensor is removed from the port, the valve biases into a closed position covering the opening, to prevent leaks. The ventilator can then continue to operate without the oxygen sensor in place.