Patents Issued in September 13, 2016
  • Patent number: 9440875
    Abstract: Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: September 13, 2016
    Assignee: Corning Incorporated
    Inventors: Adam James Ellison, Timothy James Kiczenski
  • Patent number: 9440876
    Abstract: An electron definable glass or an electron sensitive glass for microstructures is provided with microstructures and optical waveguides formed therein. The microstructures are formed by electron beam irradiation in selected areas in the electron definable glass followed by a high temperature heat treatment and chemical etching, whereas the optical waveguides are formed by irradiating the electron definable glass by an electron beam followed by a low temperature heat treatment.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: September 13, 2016
    Inventors: Lu Han, Andy Shih, Yi-Chi Shih, Ishiang Shih, Cindy X. Qiu
  • Patent number: 9440877
    Abstract: The present disclosure relates to fusion formable highly crystalline glass-ceramic articles whose composition lies within the SiO2—R2O3—Li2O/Na2O—TiO2 system and which contain a silicate crystalline phase comprised of lithium aluminosilicate (?-spodumene and/or ?-quartz solid solution) lithium metasilicate and/or lithium disilicate. Additionally, these silicate-crystal containing glass-ceramics can exhibit varying Na2O to Li2O molar ratio extending from the surface to the bulk of the glass article, particularly a decreasing Li2O concentration and an increasing Na2O concentration from surface to bulk. According to a second embodiment, disclosed herein is a method for forming a silicate crystalline phase-containing glass ceramic.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: September 13, 2016
    Assignee: Corning Incorporated
    Inventors: George Halsey Beall, Nicholas Francis Borrelli, Charlene Marie Smith, Steven Alvin Tietje
  • Patent number: 9440878
    Abstract: A down-drawable glass ceramic. The glass ceramic has a composition which yields a liquidus viscosity that enables formation of the parent glass by down-draw techniques such as fusion-draw and slot-draw methods. The resulting glass ceramic is white or translucent in appearance with high strength achieved through heat treatment of the fusion-formed glass.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: September 13, 2016
    Assignee: Corning Incorporated
    Inventors: George Halsey Beall, Heather Debra Boek, Alexandre Michel Mayolet, Mark Owen Weller
  • Patent number: 9440879
    Abstract: A graphene coated optic fiber is disclosed. An optic fiber core is encapsulated within a graphene capsule. An optic fiber having cladding layer encapsulated within a graphene capsule is also disclosed. The graphene capsule may comprise a single layer of graphene, bi-layer of graphene, or multiple layers of graphene. An optical circuit is disclosed that transmits ultraviolet light across an optic fiber encapsulated with graphene.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: September 13, 2016
    Inventor: Tyson York Winarski
  • Patent number: 9440880
    Abstract: A method of manufacturing a sealed structure with excellent hermeticity and a method of manufacturing a light-emitting device sealed with the sealed structure. In the methods of manufacturing a sealed structure and a light-emitting device using a glass frit layer, a first step of forming a buffer layer for preventing a crack generated in a substrate and the glass frit layer by laser light irradiation, a second step of forming the glass frit layer to overlap with the buffer layer over the substrate, and a third step of welding the substrates by irradiating the glass frit layer or the buffer layer with laser light are performed, whereby a sealed structure with high hermeticity and a reliable light-emitting device sealed with the sealed structure can be manufactured. By applying the method of manufacturing a light-emitting device especially to an organic EL element, a highly reliable light-emitting device can be obtained.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: September 13, 2016
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventor: Akihisa Shimomura
  • Patent number: 9440881
    Abstract: A method for designing and manufacturing micro reinforced concrete that produces a composite material that shares physical properties with both the reinforcing material and the concrete. Micro reinforced concrete is a two-part system that made of micro reinforcements, which are twisted steel fibers, and a concrete matrix. The micro reinforcements are added at a specified dose to an ordinary concrete matrix to create the micro reinforced concrete.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: September 13, 2016
    Assignee: Polytorx, LLC
    Inventors: Luke Pinkerton, Joseph L. Stecher, Jeffrey Novak
  • Patent number: 9440882
    Abstract: A lightweight concrete containing polyethylene terephthalate in an amount of 20% by total volume. The concrete is enriched with hydrogen and is therefore highly effective at thermalizing neutrons. The concrete can be used independently or as a component of an advanced neutron radiation shielding system.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: September 13, 2016
    Assignee: JEFFERSON SCIENCE ASSOCIATES, LLC
    Inventors: Paul Daniel Brindza, Bert Clayton Metzger
  • Patent number: 9440883
    Abstract: Disclosed is a cementitious product, the product comprising a liquid medium, a hydraulic binding agent, a latex polymer and optionally one or more other components, wherein the direct tensile strength of the product as determined by ASTM C307 is at least 120% of a predicted direct tensile strength of the product per an equation selected from the group consisting of f?dt=0.06*f?c, f?dt=0.07*f?c, f?dt=0.08*f?c and f?dt=0.11*f?c, and wherein the the flexural strength of the product as determined by ASTM C348 is at least 150% of a predicted flexural strength of the product per an equation selected from the group consisting of f?r=0.1*f?c, f?r=0.17*f?c, f?r=9.5*((f?c)^0.5) and f?r=7.5*((f?c)^0.5).
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: September 13, 2016
    Inventor: Joshua V. Brien
  • Patent number: 9440884
    Abstract: An epoxy grout system comprises a first epoxy resin component comprising a novolac epoxy resin, a bisphenol F epoxy resin, and a non-reactive diluent, and a second epoxy curing agent component comprising an amidoamine. The epoxy grout system has excellent chemical resistance while maintaining good installation properties. Another epoxy grout system comprises a first epoxy resin component which is resistant to a mixture of oleic acid and water, a second epoxy resin component which is less resistant to a mixture of oleic acid and water than the first component, and a third amine-containing curing agent component operable to cure both the first and second epoxy resin components. Optionally, the curing agent component can be provided as a plurality of amine-containing curing agent components of respective colors, whereby a user can select a curing agent component of a desired color for use with either the first or second epoxy resin component.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: September 13, 2016
    Assignee: CUSTOM BUILDING PRODUCTS, INC.
    Inventor: Anthony D. Pham
  • Patent number: 9440885
    Abstract: A dielectric ceramic composition includes at least dielectric particles having a core-shell structure and segregation particles, a concentration of a rare earth compound in the segregation particle is twice or more than an average concentration of the rare earth compound in a shell part of the dielectric particle having the core-shell structure, an area occupied by the segregation particles is 0.1 to 1.1%, when a maximum particle size of the segregation particle is defined as rbmax, a minimum particle size of the segregation particle is defined as rbmin, and an average particle size of the dielectric particle having the core-shell structure is defined as ra, a relation of rbmax/ra?2.00 and rbmin/ra?0.25 is satisfied, and the segregation particles substantially do not include Mg.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: September 13, 2016
    Assignee: TDK CORPORATION
    Inventors: Nobuto Morigasaki, Takeru Yoshida, Tomohisa Fukuoka, Yuhta Matsunaga, Kazuhiro Komatsu
  • Patent number: 9440886
    Abstract: A solid sintered ceramic article may include a solid solution comprising Y2O3 at a concentration of approximately 30 molar % to approximately 60 molar %, Er2O3 at a concentration of approximately 20 molar % to approximately 60 molar %, and at least one of ZrO2, Gd2O3 or SiO2 at a concentration of approximately 0 molar % to approximately 30 molar %. Alternatively, the solid sintered ceramic article a solid solution comprising 40-100 mol % of Y2O3, 0-50 mol % of ZrO2, and 0-40 mol % of Al2O3.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: September 13, 2016
    Assignee: Applied Materials, Inc.
    Inventors: Jennifer Y. Sun, Biraja P. Kanungo
  • Patent number: 9440887
    Abstract: The present invention provides a silicon nitride sintered body comprising a silicon nitride crystalline particle and a grain boundary phase, the silicon nitride sintered body having an area ratio of the grain boundary phase per 100 ?m×100 ?m unit area of 15 to 35% when an arbitrary cross section thereof is photographed. Further, it is preferable that the area ratio of the grain boundary phase per 100 ?m×100 ?m unit area is 15 to 25%. Furthermore, the silicon nitride sintered body is suitable for a wear resistant member. Due to above structure, there can be provided a silicon nitride sintered body and a wear resistant member having a high processability (workability) and an excellent sliding property.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: September 13, 2016
    Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA MATERIALS CO., LTD.
    Inventors: Kai Funaki, Michiyasu Komatsu, Haruhiko Yamaguti, Katsuyuki Aoki
  • Patent number: 9440888
    Abstract: Fabricating a composite material part comprises the steps of making a consolidated fiber preform, the fibers of the preform being carbon or ceramic fibers that are coated in an interphase formed by at least one layer of pyrolytic carbon (PyC) or of boron-doped carbon (BC). Obtaining a partially densified consolidated fiber preform, where partial densification comprises forming a first matrix phase on the interphase, the first matrix phase comprising a plurality of layers of self-healing material alternating with one or more layers of PyC or of BC. Continuing densification by dispersing carbon and/or ceramic powder within the partially densified consolidated preform and by infiltrating molten silicon or a liquid composition formed for the most part of silicon.
    Type: Grant
    Filed: November 22, 2012
    Date of Patent: September 13, 2016
    Assignee: HERAKLES
    Inventors: Eric Bouillon, Eric Philippe, Andre Lafond, Franck Lamouroux
  • Patent number: 9440889
    Abstract: The invention relates to processes for reducing ammonia loss and odor from organic material or waste to the atmosphere. A plasma generator is applied to upgrade organic waste and manure with a mixture of acidic nitrates and nitrites. The present invention also relates to an acidic nitrate solution, suitable for reducing ammonia loss and odor from organic material or waste to the atmosphere, and a process for producing such an acidic nitrate solution. The invention further comprises plants for reducing ammonia loss and odor from organic material or waste to the atmosphere.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: September 13, 2016
    Assignee: N2 APPLIED AS
    Inventor: Rune Ingels
  • Patent number: 9440890
    Abstract: Reaction products and methods for making and using the same are provided. The reaction products particularly may include adducts of two or more reactants. The adducts particularly can incorporate a nitrification inhibitor, such as DCD. In particular embodiments, reaction products may be formed from the reaction of formaldehyde, DCD, urea, and an ammonia source. The adducts may be included in agricultural products, including fertilizer compositions and nitrification inhibitor systems. Fertilizer compositions including the adducts can be beneficial for reducing leaching of nitrification inhibitors applied to soil.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: September 13, 2016
    Assignee: KOCH AGRONOMIC SERVICES, LLC
    Inventors: Kurt D. Gabrielson, Mary L. Epling
  • Patent number: 9440891
    Abstract: The present invention is directed to methods of forming olefins, especially linear alpha olefins from fatty acids or anhydrides, each method comprising: contacting an amount of precursor carboxylic acid anhydride with a palladium catalyst comprising a bidentate bis-phosphine ligand in a reaction mixture so as to form an olefin in a product with the concomittant formation and removal of CO and water from the reaction mixture, either directly or indirectly, wherein the reaction mixture is maintained with a sub-stoichiometric excess of a sacrificial carboxylic acid anhydride, an organic acid, or both, said sub-stoichiometric excess being relative to the amount of the precursor carboxylic acid anhydride. The precursor carboxylic acid anhydride may be added to the reaction mixture directly or formed in situ by the reaction between at least one precursor carboxylic acid with a stoichiometric amount of the sacrificial acid anhydride.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: September 13, 2016
    Assignee: California Institute of Technology
    Inventors: Yiyang Liu, Brian M. Stoltz, Robert H. Grubbs, Alexey Fedorov, Kelly E. Kim
  • Patent number: 9440892
    Abstract: Methods, catalysts, and reactor systems for producing in high yield aromatic chemicals and liquid fuels from a mixture of oxygenates comprising di- and polyoxygenates are disclosed. Also disclosed are methods, catalysts, and reactor systems for producing aromatic chemicals and liquid fuels from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like; and methods, catalysts, and reactor systems for producing the mixture of oxygenates from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like. The disclosed catalysts for preparing the mixture of oxygenates comprise a Group VIII metal and a crystalline alumina support.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 13, 2016
    Assignee: Virent, Inc.
    Inventors: Taylor Beck, Brian Blank, Casey Jones, Elizabeth Woods, Randy Cortright
  • Patent number: 9440893
    Abstract: In a process for producing para-xylene, benzene and/or toluene is alkylated with methanol in the presence of a catalyst under conditions including a temperature of at least 500° C. and an H2O partial pressure of at least 12 psia (83 kPaa). The catalyst comprises from 5 to 15 wt % ZSM-5, phosphorus or a compound thereof and a binder and has been steamed at a temperature of at least 900° C. The steamed catalyst has no more than two peaks in the 31P MAS NMR spectrum in the range of 0 to ?50 ppm.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: September 13, 2016
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Terry E. Helton, Robert G. Tinger, Lu Han, Andrea P. Wight
  • Patent number: 9440894
    Abstract: A process for upgrading residuum hydrocarbons is disclosed. The process may include: contacting a residuum hydrocarbon fraction and hydrogen with a first hydroconversion catalyst in a first ebullated bed hydroconversion reactor system; recovering a first effluent from the first ebullated bed hydroconversion reactor system; solvent deasphalting a vacuum residuum fraction to produce a deasphalted oil fraction and an asphalt fraction; contacting the deasphalted oil fraction and hydrogen with a second hydroconversion catalyst in a second hydroconversion reactor system; recovering a second effluent from the second hydroconversion reactor system; and fractionating the first effluent from the first ebullated bed hydroconversion reactor system and the second effluent from the second hydroconversion reactor system to recover one or more hydrocarbon fractions and the vacuum residuum fraction in a common fractionation system.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: September 13, 2016
    Assignee: Lummus Technology Inc.
    Inventors: Mario C. Baldassari, Ujjal K. Mukherjee, Ann-Marie Olsen, Marvin I. Greene
  • Patent number: 9440895
    Abstract: A system includes an amine gas processing controller that includes one or more tangible, non-transitory, machine-readable media collectively storing one or more sets of instructions and one or more processing devices configured to execute the one or more sets of instructions to operate a contactor to remove an acid gas from an untreated natural gas using an amine in a lean amine, output a treated natural gas, and output a rich amine stream, operate a regenerator to regenerate the amine in the rich amine stream, output the lean amine stream, and output the acid gas, transfer the rich amine stream from the contactor to the regenerator using an isobaric pressure exchanger (IPX), and transfer the lean amine stream from the regenerator to the contactor using the IPX.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: September 13, 2016
    Assignee: ENERGY RECOVERY, INC.
    Inventors: James Lee Arluck, Jeremy Grant Martin, Prem Krish, John Sienkiewicz
  • Patent number: 9440896
    Abstract: Disclosed is a process for producing hexafluoro-2-butyne comprising, reacting HCFC-336 with an aqueous solution of an alkali metal hydroxide in the presence of a quaternary alkylammonium salt which comprises at least one alkyl group of at least 8 carbons, and recovering the hexafluoro-2-butyne, wherein the conversion of dichloro-1,1,1,4,4,4-hexafluorobutane is at least 50% per hour. Also disclosed is a process for producing hexafluoro-2-butyne comprising, reacting HCFC-336 with an aqueous solution of an alkali metal hydroxide in the presence of a quaternary alkylammonium salt having alkyl groups of from four to ten carbon atoms, and mixtures thereof, and a non-ionic surfactant, and recovering the hexafluoro-2-butyne, and wherein the conversion of dichloro-1,1,1,4,4,4-hexafluorobutane to hexafluoro-2-butyne is at least 20% per hour.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: September 13, 2016
    Assignee: THE CHEMOURS COMPANY FC, LLC
    Inventors: Sheng Peng, Mario Joseph Nappa
  • Patent number: 9440897
    Abstract: The invention provides a process for the preparation of monoethylene glycol from sucrose comprising the steps of: i) hydrolyzing sucrose to form a reaction product stream comprising glucose and fructose; ii) separating the reaction product stream comprising glucose and fructose into a fructose or fructose derivative rich stream and a glucose rich stream; and iii) contacting the glucose rich stream with hydrogen in a reactor in the presence of a solvent and a catalyst system with catalytic hydrogenation abilities to produce a product stream comprising monoethylene glycol.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: September 13, 2016
    Assignee: SHELL OIL COMPANY
    Inventors: Jean Paul Andre Marie Joseph Gishlain Lange, Pieter Huizenga
  • Patent number: 9440898
    Abstract: In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: September 13, 2016
    Assignee: PIONEER ENERGY
    Inventors: John T. Henri, Jan Zygmunt, Mark Berggren, Robert Zubrin
  • Patent number: 9440899
    Abstract: A method of separating a secondary alcohol compound from a primary alcohol compound using selective acylation is provided.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: September 13, 2016
    Assignee: Rohm and Haas Electronic Materials LLC
    Inventors: Christopher D. Gilmore, Chi-Wan Lee, Peter Trefonas, III, William Williams, III, Qiuzhe Xie
  • Patent number: 9440900
    Abstract: A production method of ?,?-difluoroacetaldehyde according to the present invention includes reaction of an ?,?-difluoroacetic acid ester with hydrogen gas (H2) in the presence of a ruthenium catalyst. It is possible to selectively obtain ?,?-difluoroacetaldehyde as a partially reduced product of the hydrogenation reaction by the adoption of specific reaction conditions (in particular, reaction solvent and reaction temperature). This hydrogenation process can be alternative to the industrially unpractical hydride reduction process.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: September 13, 2016
    Assignee: Central Glass Company, Limited
    Inventors: Takashi Ootsuka, Mari Imamura, Akihiro Ishii, Koji Ueda, Shunsuke Mimura
  • Patent number: 9440901
    Abstract: Provided is a production method of Form I crystal of reduced coenzyme Q10 or a crystalline solid thereof, which is substantially free of Form II crystal, including a step of holding a solution containing reduced coenzyme Q10 at a temperature exceeding 47° C. for at least 60 minutes, and a step of crystallization thereafter.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: September 13, 2016
    Assignee: KANEKA CORPORATION
    Inventors: Hideo Kawachi, Shiro Kitamura, Yasuyoshi Ueda
  • Patent number: 9440902
    Abstract: To provide a production method for suppressing the reduction in production rate of a carbonyl compound due to transferring a noble metal component into liquid phase. A method for producing a carbonyl compound, including: a reaction step of reacting a carbonylation raw material with CO in liquid phase including a solid catalyst having noble metal complex on a resin carrier containing quaternized nitrogen to produce a carbonyl compound; a distillation step of distilling a reaction product liquid to recover gas phase distillate including the carbonyl compound; and a circulation step of circulating a bottom product from the distillation to reaction step. After part of the bottom product contacts with an acidic cation-exchange resin to remove nitrogen compound, liquid having higher moisture concentration than the bottom product contacts with the resin to extract noble metal complex captured by oligomer adsorbing the resin, and the complex is returned to the reaction step.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: September 13, 2016
    Assignee: CHIYODA CORPORATION
    Inventors: Zhixiong You, Yoichi Umehara, Tetsuro Matsumura, Takeshi Minami
  • Patent number: 9440903
    Abstract: The present disclosure relates to a single shell open interstage reactor (“SSOI”). The SSOI comprises a first reaction stage, an interstage heat exchanger, an open interstage region, and a second reaction stage. The SSOI may be configured for upflow or downflow operation. Further, the open interstage region of the SSOI may comprise a supplemental oxidant feed. When the open interstage region comprises a supplemental oxidant feed, the SSOI may further comprise a supplemental oxidant mixing assembly. Processes for producing acrylic acid through the oxidation of propylene are also disclosed.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: September 13, 2016
    Assignee: Arkema Inc.
    Inventors: Michael S. DeCourcy, John L. Steinbach, Nicolas Dupont, Roger L. Roundy
  • Patent number: 9440904
    Abstract: Provided is a method capable of producing acrolein and/or acrylic acid, or methacrolein and/or methacrylic acid, stably in a high yield over a long period of time advantageously even in a high-load reaction, and the method is a method in which when preparing two or more kinds of catalysts having different formulations and stacking two or more layers in the axial direction of the tube, the catalysts are filled in such a manner that not only the component amount of bismuth relative to molybdenum decreases from the gas inlet side toward the gas outlet side, but also the component amount of iron relative to molybdenum increases from the gas inlet side toward the gas outlet side.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: September 13, 2016
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yuuta Nakazawa, Tatsuhiko Kurakami, Kazuo Shiraishi
  • Patent number: 9440905
    Abstract: The disclosure provides anionic Gemini surfactants comprising at least two carbonyl moieties and at least two aliphatic moieties. In some aspects, at least two of the aliphatic moieties comprise at least seven carbon atoms and at least one pair of conjugated carbon-to-carbon double bonds. The anionic Gemini surfactants are polymerizable and may be used to prepare triply periodic multiply continuous lyotropic phase and polymers thereof that substantially retain triply periodic multiply continuous lyotropic phase structure.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: September 13, 2016
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Mahesh Kalyana Mahanthappa, Gregory Paul Sorenson
  • Patent number: 9440906
    Abstract: The present invention relates to a novel crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the invention relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning calorimetry (DSC).
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: September 13, 2016
    Assignee: LEO Laboratories Limited
    Inventor: Steven Martin Ogbourne
  • Patent number: 9440907
    Abstract: Provided is a method for producing a 2-alkenylamine compound efficiently and at low cost, using a primary or secondary amine compound and a 2-alkenyl compound as the starting materials therefor. The 2-alkenylamine compound is produced by adding Bronsted acid when 2-alkenylating by reacting the primary or secondary amine compound with the 2-alkenyl compound, and 2-alkenylating in the presence of a catalyst comprising a complexing agent and a transition metal precursor stabilized by a monovalent anionic five-membered conjugated diene.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: September 13, 2016
    Assignees: SHOWA DENKO K.K., NATIONAL UINVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Yoshitaka Ishibashi, Naoya Fukumoto, Masato Kitamura
  • Patent number: 9440908
    Abstract: The present invention relates to a process for preparing N-(5-chloro-2-isopropylbenzyl)cyclopropanamine by hydrogenation of N-[(5-chloro-2-isopropylphenyl)methylene]cyclopropanamine over specific platinum catalysts.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: September 13, 2016
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Thomas Himmler, Sandra Lehmann, Thomas Norbert Muller, Mathias Riedrich, Lars Rodefeld, Frank Volz, Sascha Von Morgenstern
  • Patent number: 9440909
    Abstract: Methods for making sulfide scavenging compositions are provided. The method comprises reacting at least one secondary amine with at least one aldehyde and solvent in the presence of a catalyst to form a reaction composition, wherein a reaction temperature is less than or equal to 90° C. Sulfide scavengers using the above method are also disclosed. Methods for removing sulfides from fluid streams are also provided. The methods include adding the above sulfide scavengers to fluid streams.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: September 13, 2016
    Assignee: General Electric Company
    Inventor: Gregory Kaplan
  • Patent number: 9440910
    Abstract: The present invention relates to the new impurities of Fesoterodine, Fesoterodine symmetric dimer impurity and asymmetric dimer impurity, process for preparing and isolating thereof. The invention also deals with analytical standards and analytical methods used for the control of the production process and final quality of Fesoterodine.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: September 13, 2016
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Venkatraman Jayaraman, Sundara Kalyana Balaji, Samir Patel, Thakor Indrajit, Viral Parekh, Mahesh Ladani, Chetan Patil, Ronak Patel, Darshan Parmar
  • Patent number: 9440911
    Abstract: The invention relates to a hydrophilically modified multifunctional amine AC which has more than one primary amino group per molecule, and at least one group per molecule derived from the reaction of an epoxide group with a reactive group selected from the group consisting of secondary amino groups >NH, hydroxyl groups —OH, mercaptan groups —SH, amide groups —CO—NHR, where R can be hydrogen or an alkyl group having from one to twelve carbon atoms, hydroxyester groups, and acid particularly carboxyl groups —COOH, sulphonic acid groups —SO3H, and phosphonic acid groups —PO3H2, and preferably, also moieties which are compatible with an epoxy resin, as well as a process for its preparation, and a method of use thereof.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: September 13, 2016
    Assignee: ALLNEX AUSTRIA GMBH
    Inventors: Florian Lunzer, Rudolf Schipfer, Günther Monschein, Ursula Meisner, Albine Kernbichler
  • Patent number: 9440912
    Abstract: Disclosed is a process for isomerizing cis-2-pentenenitrile to 3-pentenenitrile in the presence of a non-aluminum metal oxide catalyst, wherein: (a) the metal in the catalyst has an oxidation state in the range from +1 to +4; (b) the metal has a cation radius in the range from 0.35 to 1.0 ?; (c) the metal of the catalyst has a polarizing power, C/r, is in the range from 2 to >8, wherein C is the charge of the metal and r is the ionic radius in ?; (d) the bond network of the catalyst has a % ionicity of >20; (e) the metal oxide has an acidity strength in the range from strong to very weak; and (f) the metal oxide has a basicity (nucleophilicity) strength of weak to strong.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 13, 2016
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Sudhir N. V. K. Aki, William J. Tenn, III, Thomas E. Vos
  • Patent number: 9440913
    Abstract: Novel compounds below are useful for preventing or treating diseases caused by protozoans. At least one of a compound represented by Formula (I) (wherein, X represents a hydrogen atom or a halogen atom; R1 represents a hydrogen atom; R2 represents a hydrogen atom or a C1-7 alkyl group; R3 represents —CHO, —C(?O)R5, —COOR5 (wherein R5 represents a C1-7 alkyl group), —CH2OH or —COOH; and R4 represents a C1-16 alkyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), a C2-16 alkenyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), or a C2-16 alkynyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s)), an optical isomer thereof, and a pharmaceutically acceptable salt is used.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: September 13, 2016
    Assignee: NAI INC.
    Inventors: Hiroyuki Saimoto, Kiyoshi Kita, Yoshisada Yabu, Masaichi Yamamoto
  • Patent number: 9440914
    Abstract: Methods of treating an astrocytoma with agents effective to inhibit microglia function are provided, as well as methods of enhancing the efficacy of brain tumor radiation therapy on an astrocytoma in a subject. Also provided are methods of treating other solid tumor types, and tumor cell invasion, with guanylhydrazone compounds.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 13, 2016
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Yousef Al-Abed, Marc Symons
  • Patent number: 9440915
    Abstract: Disclosed is a method for preparing methanedisulfonic acid, comprising an acidification, wherein the acidification comprises that methanedisulfonate reacts with an acidifier to form a mixture containing methanedisulfonic acid. The disclosure has high yield, low cost, and the process are environmental friendly.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: September 13, 2016
    Assignee: HUNAN ASTAR BIO-CHEMICAL TECHNOLOGY CO., LTD.
    Inventor: Zongming Yi
  • Patent number: 9440916
    Abstract: The present invention is directed to a method of treating an inflammatory skin disease or disorder, such as dermatitis, psoriasis, acne, or rosacea. The method comprises administering to the subject 3, 4-bis-benzylsulfonylbutyronitrile in an amount effective to reduce or eliminate the symptoms of the inflammatory skin disease or disorder. Topical administration and oral administration are preferred route of administration.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: September 13, 2016
    Assignee: OLATEC THERAPEUTICS LLC
    Inventors: Joseph P. St. Laurent, Gerald S. Jones, David M. Bresse, Scott A. Goodrich
  • Patent number: 9440917
    Abstract: A process is described for preparing 4-haloalkyl-3-mercapto-substituted 2-hydroxybenzoic acid derivatives of the general formula (I) by reaction of 4-thio-substituted ?-keto esters of the formula (II) with alkoxyvinyl haloalkyl ketones of the formula (III) in the presence of a base. In the above formulae, X, R1, R2 and R3 are each hydrogen, halogen, alkyl, alkoxy and cycloalkyl.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: September 13, 2016
    Assignee: Bayer Cropscience AG
    Inventors: Mark James Ford, Gunter Karig
  • Patent number: 9440918
    Abstract: A method for purifying (S)-oxiracetam is disclosed. Crude (S)-oxiracetam with the purity of 89% is dissolved in water; the solution is allowed to stand for 1 to 3 days at 0° C. to 18° C.; a colorless transparent crystal is precipitated; the solution is filtered and top-washed with cold water to 0° C. to 5° C.; and the product is dried in vacuum to obtain high-purity (S)-oxiracetam.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: September 13, 2016
    Assignee: CHONGQING RUNZE PHARMACEUTICAL CO., LTD.
    Inventors: Lei Ye, Zuyuan Rong
  • Patent number: 9440919
    Abstract: Disclosed herein are compositions and methods of treating osteoporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I) or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: September 13, 2016
    Assignees: Cayman Chemical Company, Inc., Myometrics, LLC
    Inventors: Stephen Douglas Barrett, Fred Lawrence Ciske, Joseph Michael Colombo, Gregory William Endres, Bradlee David Germain, Andriy Kornilov, James Bernard Kramer, Adam Uzieblo, Thomas Allen Owen, James Paul O'Malley
  • Patent number: 9440920
    Abstract: Described herein are antimicrobial compounds identified via a high-throughput screen to identify compounds that produce anucleate cells in E. coli after cell division occurs. Compound 1 (5-nonyloxytryptamine) and its analogs are small molecule inhibitors of the nucleoid occlusion system and/or proteins that are responsible for maintaining the structure of the chromosome. The antimicrobial compounds are useful to treat bacterial infections as well as to inhibit bacterial growth.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: September 13, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Douglas Benjamin Weibel, Katherine Ann Hurley, Katherine Cassidy Faulkner
  • Patent number: 9440921
    Abstract: 3-n-Butyl-1-isoindolinone and use thereof for preventing or treating cerebral infarction. The compound is prepared by: 1) employing phthalimide as a starting reactant, contacting a nucleophilic Grignard reagent with the original reactant to add an alkyl group to a carbonyl carbon of an amide bond of the original reactant, thus yielding an intermediate; and 2) removing an oxygen atom connected to a third carbon atom of the intermediate in the presence of boron trifluoride diethyl etherate as a catalyst and triethylsilane as a reductant.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: September 13, 2016
    Assignees: SUN YAT-SEN UNIVERSITY
    Inventors: Chunshun Zhao, Wenkai Xu
  • Patent number: 9440922
    Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: September 13, 2016
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazutomo Kinoshita, Kohsuke Asoh, Noriyuki Furuichi, Toshiya Ito, Hatsuo Kawada, Nobuya Ishii, Hiroshi Sakamoto, WooSang Hong, MinJeong Park, Yoshiyuki Ono, Yasuharu Kato, Kenji Morikami, Takashi Emura, Nobuhiro Oikawa
  • Patent number: 9440923
    Abstract: 4,5,6-Trichloropicolinic acid is prepared by selectively dechlorinating 3,4,5,6-tetrachloropicolinic acid with zinc and a catalyst prepared from a nickel compound and a bidentate ligand in a polar solvent.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: September 13, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Matthew L. Grandbois, David S. Laitar, James M. Renga, Gregory T. Whiteker
  • Patent number: 9440924
    Abstract: The present invention relates to a novel solvate of ivabradine hydrochloride, a process of its preparation and its use for the preparation of specific polymorphic forms of ivabradine hydrochloride.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: September 13, 2016
    Assignee: SANDOZ AG
    Inventors: Josef Wieser, Ulrich Griesser, Michael Enders, Volker Kahlenberg