Abstract: A process and kit for decontaminating crumb rubber or synthetic turf involves use of an antimicrobial agent for killing microorganisms embedded within or upon the crumb rubber or the synthetic turf, and/or subsequently using a non-pathogenic microbe to degrade organic materials in the crumb rubber or synthetic turf which degrades organic materials which may harbor odor causing organisms therefore preventing them from becoming established.

Abstract: A lighted air freshener assembly provides a fragranced odor and illumination as well as the ability to be hung from a support structure, such as a Christmas tree. The assembly includes a support base having a top wall, a bottom wall and a perimeter wall coupled to and extending between the top wall and the bottom wall. At least one light emitter is coupled to the support base. A scent device is coupled to the support base and includes a scented material for emitting a fragranced odor. A decorative casing is positionable over the scent device and is removably couplable to the support base.

Abstract: A controlled diffuser device can include a cover, a louver panel, a substrate member, and a base is disclosed. A cover and a base can be configured to affix to each other to sandwich a substrate member and a louver panel while enabling a substrate member and louver panel to slidably engage a base upper surface. A substrate member may comprise a material that changes in a physical dimension as it diffuses aromatic components. Because of static securement and slidable engagement configurations, a louver panel operatively shutters apertures of a cover to selectively moderate varying degrees of exposure of a substrate member as a substrate member changes in a physical dimension. Other embodiments may include a base configured to receive a substrate member and have a cover placed over top. As the substrate changed in physical dimension, the cover can be caused to move relative to the base.

Abstract: A sterilization apparatus for sterilizing air includes an outer housing having side walls extending between opposed bottom and top walls that, together, define an outer chamber. An inner housing is situated in the outer chamber and includes opposed top and bottom ends and having a wall structure that defines a sealed inner chamber extending therebetween. The wall structure includes at least one side wall that defines a transparent window. An inlet port is in communication with one end of the inner chamber and that directs unsterilized air into the inner chamber. An ultraviolet (“UV”) light source is positioned outwardly adjacent the window and configured to emit UV light through the window and into the inner chamber when energized so as to sterilize air in the inner chamber. An outlet port is in communication with another end of the inner chamber that directs sterilized air downstream from the inner chamber.

Abstract: A rod-shaped fluorescent UV light bulb affixed to a socket comprises an ultraviolet (UV) air sanitizing fixture for commercial aircraft, public transit, or heavy equipment. Electric power is provided by the vehicle electrical system. The fixture is installed by insertion into a small circular aperture which has been cut or drilled into the sheet metal of the air circulation ductwork of the vehicle, and securing the socket to the sheet metal.

Abstract: Several embodiments disclosed herein relate to compositions and methods for treating or repairing damage to ocular tissue. In particular, several embodiments relate to patches that interact, e.g., by way of an adhesive, with damaged retinal tissue to repair or mend a hole, tear or detachment of the retina from underlying ocular tissue. Still additional embodiments relate to self-assembling patches.

Abstract: This invention claims hot melt adhesive compositions that can be used to form elastic composites that are useful in disposable absorbent articles. The compositions have good elastic recovery and high peel adhesion at a viscosity of less than about 20,000 cps at 177° C. The low viscosity makes it possible to apply the adhesive at a high line speed and target application to only those areas requiring elastic performance.

Abstract: Ultra-low crosslinked microgels made of an ultra-low crosslinked polymer are provided. The microgels, also referred to as Platelet-like Particles (PLPs), preferably have <0.5% crosslinking densities. One or more of the polymers are conjugated with a fibrin-binding element or moiety, preferably H6, in an amount effective to confer to the microgel selective binding to fibrin under physiological conditions. The PLPs can recapitulate multiple key functions of platelets including binding, stabilizing and enhancing fibrin clot formation, responsiveness to injury cues, and induction of clot contraction. In a preferred embodiment, the microgel or PLP has little or no binding to soluble fibrinogen under physiological conditions compared to its binding to fibrin. The microgels or PLPs are prepared using crosslinker-free synthesis conditions, and can promote or induce clotting and clot contraction.

Abstract: Systems and methods for the treatment of pelvic and junctional hemorrhage are provided, which utilize in situ forming polymer gels and foams to apply pressure to sites of hemorrhage due to penetrating or blunt injury, among other things.

Abstract: Thus, the present invention provides a composition in powder form comprising highly dispersed silica particles, polymethylsiloxane particles, and at one or both of a cationic surfactant and an antimicrobial substance, wherein at least 25% by weight of the cationic surfactant is present in primary polymethylsiloxane particles carrying the cationic surfactant on their surface and/or in agglomerates of these primary particles, and/or at least 25% by weight, of the antimicrobial substance is present in primary highly dispersed silica particles carrying the antimicrobial substance on their surface and/or in agglomerates of these primary particles.

Abstract: Methods of making tissue fillers are provided. In certain embodiments, the tissue is flake-like and has regenerative properties.

Abstract: Provided are compositions and methods for a scaffold coated with a primer coating and a mineral coating. Also provided is a composition for a scaffold having a mineral coating similar to bone. Also provided is a method for mineral coating a scaffold so as to promote mineral coating of the scaffold with a plate-like nanostructure and a carbonate-substituted, calcium-deficient hydroxyapatite phase.

Abstract: Certain embodiments include materials that carry oxygen and emit molecular oxygen upon heating. The approach reported here uses thermal decomposition of organic endoperoxide compounds to produce singlet oxygen. In certain aspects the oxygen carrier comprises an organic compound either alone or contained in a polymeric carrier or other carrier material that is used to form a coating, layer, or bulk substance that can be a solid, a gel or a fluid. The oxygen-carrier is most conveniently prepared by oxidation of a precursor compound, the structure of which determines its thermal stability and thus how rapidly oxygen is released at any given temperature.

Abstract: A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.

Abstract: The present invention relates to a process for obtaining a compound of cellular spraying for fibroblasts and human keratinocytes and its use as regenerative agent of cutaneous lesions, mainly in diabetic ulcers, first, second, and third grade burns, and a substitute for the use of flaps techniques. The process for obtaining a compound of cellular spraying for fibroblasts and human keratinocytes includes the steps of separating the dermis and epidermis layers, incubation of the epidermis layer, disintegration of dermis layer and proliferation of fibroblasts, disintegration of the epidermis layer, proliferation of keratinocytes in suspension, preparation of the cross-linking reaction agent solution of the cellular spraying solution, and preparation of cellular spraying solution. The compound for cellular spraying of fibroblasts and human keratinocytes increases the application efficiency and ease of it, in order to be an economic alternative, fast, and easy to use.

Abstract: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.

Abstract: An implantable device and methods of inhibiting corrosion on a magnesium-based implantable device are described. The implantable device comprising a body having an external surface. The body or one or more structural members thereof is formed at least in part by metallic magnesium or an alloy thereof. The implantable device comprises a biocorrosion-inhibiting film on at least a portion of the external surface, wherein the biocorrosion-inhibiting film comprises a metal.

Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.

Abstract: Provided herein is a device comprising a stent and a coating on the stent; wherein the coating comprises at least one polymer and at least one active agent; wherein at least part of the active agent is in crystalline form.

Abstract: Air drained from a patient's body can be measured after a surgical operation or trauma. The volume of air drained from the body can be determined from the weight of a vessel that has receive effluent drained the body and the volume of air that has escaped from the vessel. The effluent can include any one or a combination of air and liquid.

Abstract: Provided is a suction device that can suppress sound and vibration during use. A suction device includes a flow-passage forming section (1) having a suction port (20) from which fluid is sucked, a discharge port (29) from which the fluid is discharged, and a flow passage (2) which is sealed from an outside except at the suction port (20) and the discharge port (29) and through which the fluid flows, and a piezoelectric driving part (33) that generates a flow of the fluid in the flow passage (2). The piezoelectric driving part (33) includes a diaphragm (37) and a piezoelectric element (34) as a moving part that transmits driving force to the fluid. The moving part is entirely disposed inside the flow passage (2).

Abstract: Manifold structures, systems, and methods are disclosed that include using longitudinal members and one or more shaped projections to cause microstrain at a tissue site. In one instance a manifold structure includes a plurality of spaced longitudinal members and at least one shaped projection coupled to at least one of the plurality of longitudinal members for creating a microstrain at a tissue site. The at least one shaped projection includes a columnar member having a distal end and includes an enlarged member positioned at the distal end of the columnar member. The columnar member has a first outer diameter (D1) and the enlarged member has a second outer diameter (D2). The second outer diameter of the enlarged member is greater than the first outer diameter of the columnar member (D2>D1). Other systems, methods, and structures are presented.

Abstract: An electrical arrangement with an implantable cable element may be provided which comprises a strain relief element which is arranged centrically in the cross section, as well as a group of conductors insulated to one another, said group being stranded around the strain relief element, and a common shielding element surrounding the electrical conductors, as well as a fluid-tight cable sheath. The implantable cable element may have a symmetrical construction.

Abstract: An axial-flow blood pump includes a housing having an inlet and an outlet opposite therefrom. An impeller located within the housing is suspended during operation by magnetic forces between magnets or magnetized regions of the impeller and a motor stator surrounding the housing, and hydrodynamic thrust forces generated by a flow of blood between the housing and a plurality of hydrodynamic thrust bearing surfaces located on the impeller. A volute may be in fluid-tight connection with the outlet of the housing for receiving blood in the axial direction and directing blood in a direction normal to the axial direction. The volute has a flow-improving member extending axially from the volute and into the housing in a coaxial direction of the housing.

Abstract: One embodiment of the invention provides a variable pitch impeller for a blood pump. The variable pitch impeller includes: a flexible polymer defining a plurality of blades extending from a first end to a second end, the blades having a resting non-zero pitch; an external shaft coupled to a first end of the flexible polymer; and an internal shaft received within the external shaft and coupled to the second end of the flexible polymer. The internal shaft and the external shaft are rotatable with respect to each other to achieve a blade pitch between about 0.0001° and about 2,880°.

Abstract: A housing for a dialysis machine, with a wall, an opening which is provided in the wall, and a door by means of which the opening can be closed. The door or an additional wall has an installation space for a device component, which can be closed by means of an additional door.

Abstract: A device with a blood pump, at least two points of access to the abdominal wall and tubes connecting the blood pump and points of access to the abdominal wall, which is known as a peritoneal dialysis system, is equipped with a CO2 removal arrangement, in order to use it tor blood oxygenation and/or CO2 removal.

Abstract: Systems and methods of disinfection of catheter connections are provided. A transfer catheter connector can include a UV-transparent window at its distal end and a sealing plunger proximal to the UV-transparent window. A solution set connector can be inserted inside a portion of the transfer catheter connector to connect a solution set and transfer catheter. The solution set connector comprises a lumen covered by a leading membrane surface; a sealing surface configured to sealingly engage the window surface, and a piercing member configured to pierce the membrane surface. The sealing plunger, membrane surface, and window define a disinfection zone. The connectors can be connected in a disinfection position configuration in which flow is not permitted between the catheters and the connectors are irradiated with UV light. After disinfection, the connectors are advanced to a flow position in which the piercing member pierces the membrane surface, enabling flow between the catheters.

Abstract: A medical device includes a mechanism configured to perform a first medical operation, a scanner and a processing circuit. The scanner is configured to scan data displayed on a computer screen by a second medical device separate from the medical device. The processing circuit is configured to receive the scanned data from the scanner. The scanned data comprises an indication that a second medical operation was performed by the second medical device. The processing circuit is configured to proceed with the first medical operation based on the indication that the second medical operation was performed by the second medical device.

Abstract: A miniaturized, integrated, microfluidic device pulls materials bound to magnetic particles from one laminar flow path to another by applying a local magnetic field gradient. The device removes microbial and mammalian cells from flowing biological fluids without any wash steps. A microfabricated high-gradient magnetic field concentrator (HGMC) is integrated at one side of a microfluidic channel. When magnetic particles are introduced into one flow path, they remain limited to that flow path. When the HGMC is magnetized, the magnetic beads are pulled from the initial flow path into the collection stream, thereby cleansing the fluid. The microdevice allows large numbers of beads and materials to be sorted simultaneously, has no capacity limit, does not lose separation efficiency as particles are removed, and is useful for cell separations from blood and other biological fluids. This on-chip separator allows cell separations to be performed in the field outside of hospitals and laboratories.

Abstract: One disclosed embodiment comprises a method for treating lesions in the carotid artery of a mammalian body. The method comprises transcervical access and blocking of blood flow through the common carotid artery (with or without blocking of blood flow through the external carotid artery), shunting blood from the internal carotid artery and treating the lesion in the carotid artery.

Abstract: Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

Abstract: A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump, the arterial line including an arterial needle; a venous line including a venous needle; and a blood leak detection device including (i) at least one electrical component, (ii) a member configured to secure the at least one electrical component onto a patient's arm adjacent to patient access of at least one of the arterial and venous needles, the at least one electrical component capable of sensing the presence of a blood leak, and (iii) a controller in operable communication with the at least one electrical component, the controller programmed to allow for an amount of expected blood seepage and to cause an alarm if blood greater than the amount of expected blood seepage is sensed by the at least one electrical component.

Abstract: A method and an apparatus for detecting hemolysis or for determining a correction factor for correcting the influence of hemolysis on the hematocrit measurement, and an extracorporeal blood treatment apparatus with a device for detecting hemolysis. The invention is based on the implementation of two different optical measuring methods for determining hematocrit, wherein the hemolysis or the correction factor is established on the basis of the hematocrit values as detected by the two measuring methods. It has been found that the hematocrit values detected by the different measuring methods show that they are influenced with different intensity by the increasing concentrations of free hemoglobin in plasma consequent to hemolysis. A preferred embodiment envisions a reflection measurement as a first measuring method and a transmission measurement as a second measuring method.

Abstract: The present invention relates to an injection device for injecting a pharmaceutical liquid drug containing a preservative. The injection device comprises a housing (1) supporting a cartridge (20) having an interior chamber (21) holding the pharmaceutical preservative containing liquid drug to be injected, and a needle cannula (10) having a front part (11) and a back part (12), which back part (12) is adapted to be in liquid communication with the interior chamber (21) of the cartridge (20). The injection device is further provided with a telescopic needle covering shield (30) which distally is provided with a reservoir (31) which holds a liquid containing the same preservatives as in the pharmaceutical preservative containing liquid drug contained in the interior chamber of the cartridge. The telescopic needle covering shield (30) is telescopic movable in relation to the needle cannula (10) by a first resilient member between a first position and a second position.

Abstract: A packaging device for packaging a fluid dispenser (200), said dispenser comprising at least one reservoir (210) containing fluid, and a dispenser unit (220) that is actuated manually so as to dispense said fluid, said packaging device comprising a casing (100) that is provided with a base body (110) and with a cover (120) that is separable from said base body (110), starting from a closed position in which said dispenser (200) is packaged in said casing (100) and going to an open position in which said dispenser (200) may be removed from said casing (100), said casing (100) including at least one projection (130) that is adapted to co-operate with said dispenser (200) at least in the closed position of the cover (120), so as to block said dispenser unit (220) and prevent it from being actuated.

Abstract: A directional sheath for use in angiography, thrombectomy and/or chemotherapy procedures. The sheath includes a distal end and proximal end, defines aperture(s) between the ends, and includes an occlusion balloon adjacent the distal end. An inflation lumen is in fluid communication with the balloon, so the balloon can be inflated to occlude a blood vessel. The sheath can include a dilator. In one method, the sheath is inserted in a blood vessel, and the balloon is inflated to occlude it. A substance is introduced through the sheath, while the distal end remains occluded by a dilator distal end. The substance passes a dilator intermediate portion and exits the sheath through the apertures, whereby the substance is introduced retrograde in the blood vessel. In another method, the sheath is introduced into a vessel having a thrombus, the balloon is inflated to occlude it, and the thrombus is pulled into the sheath.

Abstract: A connector retains a medicine reservoir in a housing. The connector snaps onto the reservoir, the connector and reservoir are inserted into an aperture in the housing, and the connector snaps into the aperture in the housing. The connector may have a tubing and needle fixed in it to insert into the reservoir. The connector does not require a particular orientation when snapped into the housing and some embodiments may rotate freely. When snapped into the housing, the connector provides an auditory cue. For removal of the connector and reservoir, the exposed portion of the connector is compressed from the side. The configuration of the connector solves several problems associated with threaded connectors or other similar connectors.

Abstract: This invention relates to an injection device for delivering a medicament to the human or animal body, in particular, but not exclusively, to a device having a replaceable medicament cartridge, including an auto-injector, wherein the injector device comprises: a housing; a piston rod for driving a bung of a medicament container; a drive mechanism including a motor for providing an output drive to the piston rod for delivering the medicament; and control means for controlling operation of the device.

Abstract: The present invention concerns a medical pump comprising: a. A hard housing comprising a top (24) and bottom (1) hard shells, within which a rigid wall (3) and a movable membrane (2) create three distinct chambers; wherein i. said movable membrane tightly separates said second (29) and third (22) chambers ii. said first and third chambers have a watertight interface iii. said second chamber (29) is designed to contain a fluid iv. said first chamber (23) comprises a first venting mean (20) which is arranged to provide a fluidic communication between said first chamber (23) and the external environment; v. said third chamber (22) comprises a second venting mean which is arranged to provide a fluidic communication between said third chamber (22) and the external environment b. A pumping element (4) located in the first chamber (23) c. A least one pressure sensor which measure the pressure gradient between the first chamber (23) and the second chamber (29) d. A fluid pathway which permits: i.

Abstract: Inadvertent activation of a portable medical device such as an ambulatory infusion pump can be reduced by locking a touchscreen of the device when it is indicated that an uninterrupted operation is to be performed. When a processor receives a device operation input from the touchscreen that indicates an uninterrupted operation is to be performed on the portable device, the touchscreen is automatically locked such that touch input at the touchscreen is not processed by the processor to navigate between or among menu screens or set pump parameters. Following completion of the uninterrupted operation, the touchscreen can be unlocked. In one embodiment, the touchscreen can be unlocked by selection of an unlock icon on the touchscreen.

Abstract: An autoinjector system for injecting a fluid medicament into a patient includes a re-usable autoinjector, and a disposable cassette loaded with a hypodermic syringe pre-filled with a fluid medicament. The autoinjector includes a first motor for injecting a needle of the hypodermic syringe into the patient and a second motor for expelling the fluid medicament from the syringe.

Abstract: Disclosed herein is a valve assembly comprising a male luer end portion and a female luer end portion and a passage for the transfer of fluids extending between the male and female luer end portions, valve means movable between a first position, in which the passage is closed, and a second position, in which the passage is open, biasing means for biasing the valve means toward the first position, and actuating means extending into the male luer end portion and coupled to the valve means to actuate the valve means when a female luer end portion of a medical accessory is engaged with the male luer end portion.

Abstract: A syringe assembly for dispensing medicine from a cartridge having a diaphragm and a piston opposite the diaphragm. The assembly includes a barrel having a hollow interior, an open proximal end, a closed distal end, and an outlet. The assembly also includes a cartridge receiver slidably receivable in the hollow interior of the barrel. The receiver includes an interior space for receiving the cartridge, an access needle extending into the interior space for puncturing the diaphragm of the cartridge. The access needle directs fluid to the barrel outlet. The cartridge receiver includes a plunger rod movable into the interior space of the cartridge receiver for engaging the piston of the cartridge to selectively force medicine in the cartridge through the access needle.

Abstract: A drug injection device is disclosed. A drug injection device, according to the present invention, comprises: a plunger which is connected to an ampoule filled with an injectable solution and applies pressure to the injectable solution in the ampoule; a manual plunger handle which is connected to one side of the plunger and manually applies pressure to the plunger; and an automatic plunger pressurizing unit which is selectively connected to the plunger in a position adjacent to same and automatically applies pressure to same by means of power.

Abstract: A syringe for use in pressurized injection of a fluid is provided herein. The syringe includes a syringe barrel comprising a polymeric material having undergone expansion by stretch blow molding and by compression molding of an inner diameter of the barrel with a core member. In certain configurations of the syringe barrel, the stretch blow molding is provided through a nozzle of the syringe. Similarly, according to a further embodiment, a syringe for use in pressurized injection of a fluid is provided. The syringe includes a syringe barrel comprising a polymeric material having undergone expansion by stretch blow molding and by shrinking an inner diameter of the syringe barrel about a core member.

Abstract: An assembly (100) for a drug delivery device is presented. The assembly comprises a housing (10) with a main axis (X), a dose setting member (2) being rotatable with respect to the housing (10) for setting a dose of a drug, an activation member (1) being axially movable with respect to the housing (10) for dispensing the dose from the drug delivery device, and a rotation member (5) being arranged between the activation member (1) and the dose setting member (2). The assembly (100) is configured such that the rotation member (5) is rotatable with respect to the dose setting member (2) and the activation member (1), wherein the outer surface (21) of the assembly (100) comprises the outer surface (22) of the rotation member (5).

Abstract: A drive assembly (180) for a drug delivery device (101) is provided, the drive assembly (180) comprising a spring member (127), a piston rod (102) and a piston rod nut (126) being engaged with the piston rod (102). The piston rod nut (126) is configured to rotate and axially move during a setting of a dose, wherein the spring member (127) is compressed when the piston rod nut (126) is moved during the setting of a dose, and wherein the piston rod nut (126) is rotationally fixed during a dispense of a dose.

Abstract: A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.

Abstract: An assembly (100) for a drug delivery device is presented. The assembly comprising a housing, a clicker member (2) and a clutch member (1) comprising a rotatable clutch feature (20). The assembly further comprises a counter clicker (8) which is configured to interact with the clicker member (2) to form a clicker mechanism, and a spring element (3) arranged between the clicker member (2) and the clutch member (1), the spring element (3) being arranged to move the clutch member (1) towards the first position and away from the clicker member (2) away from each other.