Abstract: A fluid filtration system is shown. The fluid filtration system utilizes a one-piece or multiple piece containers having a plurality of radiation-transmissible media adapted to receive light, such as ultraviolet light, white light or other wavelength light. The radiation-transmissible media are situated in the container and at least one or a plurality of radiation sources, such as ultraviolet lamps, are situated in an array in proximity to the radiation-transmissible media. The radiation-transmissible media interrupts the flow and velocity of the fluid stream passing through the container to extend the duration of radiation for any contaminants and also provide enlarged surface areas for the contaminants to be received and ultimately exposed to the radiation. In one example, the radiation-transmissible media may be tubular or spherical sections that are hollow or solid and made of quartz.

Abstract: An air purifier including an air sterilizing unit, an air blowing unit arranged such that air flows in the air sterilizing unit; the air sterilizing unit comprising housing and an ultraviolet light emitting device which emits deep ultraviolet ray having wavelength of 200 to 350 nm; the housing comprising a sterilizing room; the sterilizing room comprising an air intake opening and an air outlet opening; and the ultraviolet light emitting device being arranged in the housing such that the deep ultraviolet ray is emitted toward inside of the sterilizing room, wherein (A) at least a part of an inner wall surface of the sterilizing room comprises an ultraviolet reflective material which may be covered with an ultraviolet ray transmitting material, and/or (B) one or more reflector plate is arranged in the sterilizing room.

Abstract: A sterilization apparatus for sterilizing air includes an outer housing having side walls extending between opposed bottom and top walls that, together, define an outer chamber. An inner housing is situated in the outer chamber and includes opposed top and bottom ends and having a wall structure that defines a sealed inner chamber extending therebetween. The wall structure includes at least one side wall that defines a transparent window. An inlet port is in communication with one end of the inner chamber and that directs unsterilized air into the inner chamber. An ultraviolet (“UV”) light source is positioned outwardly adjacent the window and configured to emit UV light through the window and into the inner chamber when energized so as to sterilize air in the inner chamber. An outlet port is in communication with another end of the inner chamber that directs sterilized air downstream from the inner chamber.

Abstract: According to an embodiment of the present invention, an apparatus for ionizing air includes a first reflector and a first target. The first reflector receives direct UV energy (from a UV emitter) and reflects it to form reflected UV energy. The first target has an inner face that also receives direct UV energy (from the UV emitter). The first target also has an outer face that receives the reflected UV energy from the first reflector. The faces of the first target are coated with a photo-catalytic coating. The first target may also have passages between the faces.

Abstract: An adhesive hydrogel dressing as well as methods of applying the dressing to a patient. The dressing generally comprises an adhesive hydrogel pad, a backing layer, and an adhesive layer on the backing layer facing the hydrogel pad. The adhesive layer and backing layer form a perimeter around the hydrogel pad and hold the hydrogel pad in place on an application surface. A release element is in contact with at least a portion of the edge of the hydrogel pad proximate the area that the hydrogel pad and release liner separate during liner removal.

Abstract: Paste containing at least one monomer for radical polymerization, at least one polymer that is soluble in said at least one monomer for radical polymerization, and at least one filling agent that is poorly soluble or insoluble in said at least one monomer for radical polymerization, wherein the filling agent is a particulate inorganic filling agent possessing a BET surface of at least 40 m2/g; kit comprising pastes A and B which, when mixed, form paste C, which pastes are useful for mechanical fixation of articular endoprostheses, for covering skull defects, for filling bone cavities, for femuroplasty, for vertebroplasty, for kyphoplasty, for the manufacture of spacers or for the production of carrier materials for local antibiotics therapy, as well as a form body produced from the pastes.

Abstract: A medical implant is for insertion into a bone. The medical implant may include a zone having a polymer material configured to transition from a solid condition to a softened condition when exposed to electromagnetic radiation, and be flowable into interspaces of the bone in the softened condition. The medical implant may include a light-conducting portion configured to conduct the electromagnetic radiation from a radiation source to the zone when the medical implant is inserted into the bone.

Abstract: The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition.

Abstract: Methods to produce micro-fiber webs containing fibers of 4-hydroxybutyrate or copolymers thereof with average diameters from 0.01 to 100 ?m, have been developed. The micro-fiber webs are produced by centrifugal spinning. These methods allow the micro-fiber webs to be produced without substantial loss of the polymer weight average molecular weight. Webs containing micro-fibers of poly-4-hydroxybutyrate or copolymer thereof, are made by centrifugal spinning. The micro-fibers have average diameters ranging from 0.01 to 100 ?m and contain crimped fibers with a higher elongation at break fibers when compared to fibers derived by melt-blown extrusion, dry spinning and electrospinning. The fibers of the micro-fiber webs have a high degree of orientation. These micro-fiber webs can be used for a variety of purposes including fabrication of medical devices.

Abstract: The present invention generally relates to nanoscale wires and tissue engineering. In various embodiments, cell scaffolds for growing cells or tissues can be formed that include nanoscale wires that can be connected to electronic circuits extending externally of the cell scaffold. The nanoscale wires may form an integral part of cells or tissues grown from the cell scaffold, and can even be determined or controlled, e.g., using various electronic circuits. This approach allows for the creation of fundamentally new types of functionalized cells and tissues, due to the high degree of electronic control offered by the nanoscale wires and electronic circuits. Accordingly, such cell scaffolds can be used to grow cells or tissues which can be determined and/or controlled at very high resolutions, due to the presence of the nanoscale wires, and such cell scaffolds will find use in a wide variety of novel applications, including applications in tissue engineering, prosthetics, pacemakers, implants, or the like.

Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.

Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.

Abstract: According to some embodiments of the invention, there is provided a method of producing a bone graft, comprising: providing a tooth, converting the tooth into a plurality of particles, and selecting from available particles a subset of particles. In some embodiments, the method is performed at a dental clinic. In some embodiments, the dental bone graft is an autograft produced by grinding a patient's tooth. According to some embodiments of the invention, there is provided an apparatus configured for connecting to a motor unit to produce a bone graft at a dental clinic, comprising: a housing encasing: a chamber sized to receive a tooth, a blade assembly positioned within the chamber and configured to pulverize the tooth, an accessible compartment in which a subset of tooth particles is collected, and one or more sieves positioned to sift particles that flow between the chamber and the accessible compartment.

Abstract: Medical devices that are resistant to biofilm development and methods of the manufacture of biofilm resistant medical devices are provided. One or more bacteriophages are tethered to the surface of a medical device or a hydrogei-type coating on the surface of the device by covalent bonding while maintaining bacteriophage infective or lytic activity. The presence of the bacteriophages on a medical device, such as an indwelling medical device, prevents biofilm formation or reduces existing biofilm formation on the surface of the device when in use. These devices address the long felt need for biofilm resistant devices that increase safety and reduce complications normally associated with prior indwelling or other medical devices.

Abstract: An implant comprises a structure that may be implanted into tissue and that has a first material property at normal body temperature. The first material property is variable at elevated temperatures above normal body temperature. The implant also has a plurality of particles dispersed in the structure that are adapted to convert incident radiation into heat energy when irradiated with electromagnetic radiation. The particles are in thermal contact with the structure such that exposure of the particles to incident radiation raises the temperature of the structure thereby changing the first material property relative to the first material property at normal body temperature.

Abstract: A surface treating agent comprising a copolymer including: a monomer (A) having a hydrophilic functional group of formula (1), a monomer (B) having a basic functional group of formula (3) or (5), and a monomer (C) having a reactive functional group of formula (7), wherein the copolymer has a molar ratio of the monomer (A)/the monomer (B)/and the monomer (C) between 87/10/3 and 98/1/1. In the formulas, the R groups and n are defined.

Abstract: A canister assembly for use with a medical suction or aspiration device having a ball float assembly defined in the lid. The lid accepts a replaceable filter cartridge containing a filter element. The ball float engages the replaceable filter cartridge when the canister is near full.

Abstract: The inventions disclosed herein relate to systems for securing medical devices to a blood vessel of a patient, including securing a vessel deforming component to a blood vessel. Certain embodiments relate to wraps configured to be secured around a blood vessel, including wraps configured to hold a vessel deformer adjacent a blood vessel, and further including, for example, a pulsatile balloon adjacent the aorta.

Abstract: An implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle is disclosed. The device includes at least one pump device having a pump. The pump includes: a piston adapted for reciprocating movement, an operating device for operating the piston, and a heart contacting organ. The movement of the piston assists the pump function of the heart through the heart contacting organ.

Abstract: The invention provides systems and methods for exchanging gas in an oxygenator device, and methods for preparing and using such oxygenator devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient.

Abstract: A kit for reagents for use in an acoustic apparatus includes a first fluid that is a lysis fluid, a second fluid having an acoustic contrast that is greater than that of the first fluid, and a reagent for labeling a particle.

Abstract: One embodiment provides a method of using contextual lighting to assist a user of a medical fluid injection system. In this embodiment, the method includes providing a lighted display in proximity to a component of the injection system during setup of the medical fluid injection system. If the user has properly performed a setup function that is associated with the component of the injection system, the method further comprises providing a first visual indication on the lighted display. If the user has not properly performed the setup function that is associated with the component of the injection system, the method further comprises providing a second visual indication on the lighted display.

Abstract: Some embodiments of an infusion pump system may be configured to provide a desired level of resistance to liquid ingress to the pump casing while contemporaneously providing air transmissibility for equalization of air pressure differentials between the interior and exterior of the pump casing. Further, some embodiments can detect when moisture inside a casing of the infusion pump system is greater than or equal to a threshold level and can initiate one or more patient safety countermeasures.

Abstract: A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.

Abstract: An infusion pump system is disclosed. The system includes a syringe having a plunger within the syringe barrel, the syringe having an exit end, at least one temperature determination device adjacent to the syringe, at least one device to determine the distance the plunger has moved with respect to the syringe barrel, and a pump processor in communication with the at least one temperature determination device and the at least one optical sensor, wherein when the controller determines a change in temperature and a corresponding plunger movement, the controller increases or decreases a preprogrammed basal rate of the infusion pump by a predetermined amount for a predetermined time.

Abstract: A medical infusion device including a chamber characterized by an upper body joined to a lower body by a reversibly collapsible sidewall, affixed to the upper body is a downward extending needle, wherein the upper body has two channels, the first channel fluidly coupled to the needle and the second channel fluidly coupled to the interior of the chamber. The chamber has a collapsed state and an expanded state where chamber is configured to transition from the collapsed state to the expanded state by introducing fluid into the interior of the chamber.

Abstract: Systems, devices and methods are presented in the subject disclosure for recommending an insulin dose adapted for use with an insulin delivery device. In some embodiments, the method may include receiving blood glucose (BG) data, determining one or more insulin sensitivity (IS) values associated with the BG data, and determining an insulin dose based on the determined one or more IS values. A system for carrying out such a method is also presented.

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

Abstract: The present invention relates to a manual injection pen (1) suitable for injecting a liquid medication via a non-electrical drive mechanism (33). The injection pen (1) is provided with a plurality of sensors (50,70,200) that senses when a user is taking a specific action with the device. Further the injection pen (1) is provided with a sound generator (10) that generates a particular sound corresponding to the specific action taken by the user. In this way a characteristic sound signal can be provided for each specific action.

Abstract: The present invention relates to a medicament delivery device comprising an elongated housing (10, 10?) having opposite distal and proximal ends, a medicament container (18; 18?) arranged inside said housing, a medicament delivery member (16; 16?) attachable to said medicament container; a plunger rod (22; 22?) arranged to act on a stopper (20; 20?) inside said medicament container; driving means arranged to interact with said plunger rod; wherein said device further comprises an operation member (38; 38?) transversally protruding through an elongated opening (39; 39?) on the longitudinal surface of the elongated housing and interactively connected to the driving means for both setting and actuating the delivery of a dose of medicament.

Abstract: According to the invention, a back-end device of an auto-injector adapted to be attached to a packaged syringe comprises a plunger arranged to abut against a stopper of the packaged syringe to translate an injection needle of the packaged syringe in a proximal direction and to expel a dose of a medicament contained in the packaged syringe through the injection needle, a drive means capable of, upon release, driving the plunger in the proximal direction towards a proximal position, a rotary sleeve with a cam surface adapted to be engaged by a plunger follower formed to the plunger, a torsion spring arranged to exert a torque upon the rotary sleeve and a release element capable of, upon manual actuation, releasing the engagement of the plunger follower with the cam surface. The plunger follower is arranged to engage the cam surface to prevent the rotary sleeve from rotating with respect to the chassis in an initial state.

Abstract: A method and system for biasing a cartridge in a drug delivery device. An element for biasing a cartridge in a cartridge housing of a drug delivery device is provided. This non-plastic element does not comprise a coil spring. A self retained element for providing a spring bias to a cartridge in a cartridge holder of a drug delivery device comprises a first member having a shape that allows passage of a spindle of the drug delivery device. A portion of the first member is self retained by an internal surface of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge holder. This cartridge could be a removable cartridge.

Abstract: The present invention relates to a needleless drug-injecting system and a drug-injecting method thereof, wherein the needleless drug-injecting system comprises a controlling device and a needleless drug-injecting device. By using the needleless drug-injecting system and the drug-injecting method, a user is able to individually set a variety of parameters comprising usage dose of liquid medicine, shot pressure of liquid medicine, air flow rate, single-shot quantity of liquid medicine, continuous shot frequency of liquid medicine, and a continuous shot spacing time according to different liquid medicine. Thus, after setting the parameters, the liquid medicine can be injected into the dermis layer of the face skin of a human when the user using this needleless drug-injecting system to inject any one liquid medicine to the human face, therefore the liquid medicine would be absorbed by the face skin without hurting the human face.

Abstract: A drive mechanism for a medication delivery device is proposed, the drive mechanism comprising a housing having a proximal end and a distal end, a rotation member which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing.

Abstract: Syringe devices and accessories for providing feedback to a user are disclosed.

Abstract: An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating.

Abstract: A protective cover (4) to be used with disposable injection needles (1), such as those used for injection of insulin, which injection needles comprise a base (3) and a needle (2) fastened in the base, said protective cover comprising a hood (9) pivotably fastened on the base, said hood (9) being arranged to be pivotable, with the one and the same hand that holds a syringe on which the injection needle is arranged, between an inactive position at the side of the needle (2) of the injection needle and an active position in front of the needle (2) seen in the longitudinal direction of the needle.

Abstract: A device and method for protecting against needle sticks, including a needle protection sleeve for being coupled to an administering device to cover a needle associated with the administering device, wherein the sleeve can be moved against the force of a spring from an extended position to a retracted position and by the force of the spring from the retracted position to the extended position, the spring being carried on the needle protection sleeve.

Abstract: The present invention relates to a protection device (1) intended to at least partially cover the needle (2) of an injection device, comprising: a support (3) of the protection device (1), a sleeve (4) movable axially in translation with respect to the support (3), an arrangement (14) for returning the sleeve (4) from an injection position to a protection position, an axial guidance arrangement (29, 30) for preventing the sleeve (4) from pivoting with respect to the support (3), one peg (6) directly and at least elastically, coupled longitudinally to the support (3) or the sleeve (4) and housed in a passageway (10) defining a first section (11) and a second section (12) followed by the peg (6) from a storage position to the injection position and then to the protection position, and a safety arrangement (21; 36, 34, 35) part of which being elastically deformable, arranged in a way as to prevent the peg from returning from the second section to the first section.

Abstract: An intravenous pump system includes an intravenous pump having an air bubble detector, a separate air trap module and a patient line. The air trap module is connectable to a set interface upon which the pump can operate. The air trap module includes an air chamber capable of receiving fluids and air, a plurality of valves controlling the flow of the fluids and air, and an air vent. The patient line is connectable to the air trap module and to a patient. The air trap module includes an actuator to control the state of the valves to enable, at least during a venting mode, the pump to push air out of the air chamber via the vent without disconnecting the patient from the patient line.

Abstract: An injection device including a carrier housing in which an injection unit having at least one injection liquid container that can be pressed out can be inserted, and an actuating device which can be driven along an injection direction (R) to activate the injection unit. The actuating device includes a piercing carriage a receptacle for the injection unit, and an injection carriage which can be displaced relative to the piercing carriage. The injection carriage has an actuating plunger for acting on a plunger of the injection unit. The piercing carriage and the injection carriage can be actuated by a force application means at least in order to carry out a piercing stroke and an injection stroke, and a piercing depth (tE) of the injection unit can be set. For this purpose, the receptacle is mounted on the piercing carriage adjustably in the injection direction (R).

Abstract: Device containing sclerosant liquid for use in the treatment of blood vessels having an aerosol valve housing containing gas-entry ports. The aerosol valve housing is mounted on a canister having an expandable inner container in which the sclerosant fluid is contained. The expandable inner container is affixed to the outer opening of the canister or to the aerosol valve housing above the valve gas-entry ports so that gas taken from the interior of the expandable inner container can mix with the sclerosant liquid to create a micro foam, such that introduction of pressurized gas through the aerosol valve causes the expandable inner container to inflate to accommodate the pressurized gas.

Abstract: An inhaler for delivering a preferably powdered formulation from a blister strip having a plurality of blister pouches. In order to achieve a compact simple construction for the inhaler and an easy action for the blister strip, the carrier extends over a circumferential angle of the inhaler of less than 360°. In particular, the carrier is guided between two deflectors with an at least substantially constant curvature, and preferably, exclusively along an outer wall of the inhaler. A conveying device of the inhaler has four drive wheels of the same diameter which are arranged on a common radius and are driven by common drive means in the same direction of rotation.

Abstract: A respiratory mask assembly for delivering breathable gas to a patient includes a frame having a main body and a side frame member provided on each lateral side of the main body. Each side frame member includes an integrally formed first connector portion. A headgear assembly is removably attachable to the frame. The headgear assembly has a second connector portion adapted to be removably coupled with the first connector portion provided on the frame. The second connector portion is manually movable to a releasing position to detach the headgear assembly from the frame. The headgear assembly is rotationally adjustable with respect to the frame.

Abstract: Ventilator associated pneumonia (VAP) may be prevented in a patient, or its occurrence reduced in a population of patients, by using an anti-VAP device or an anti-VAP material such as an anti-VAP mouthpiece that absorbs secretions. By reducing the problem of bacterial-containing secretions that otherwise build up in the airway of, and elsewhere in, the intubated patient, VAP can be prevented from occurring in intubated patients, such as patients intubated with an endotracheal tube (ETT) or a nasogastric tube. Anti-VAP mouthpieces also are useable in non-intubated patients to maintain oral hygiene.

Abstract: A tracheal tube arrangement includes at least one neck strap including, a deformable material. The tracheal tube arrangement further includes at least one reinforcing member integrated into the neck strap. The reinforcing member includes a first opening for receiving a tie. The reinforcing member further includes at least one reinforcement opening for receiving a portion of the deformable material for bonding the reinforcing member to the neck strap. A method of providing a tracheal tube arrangement that has at least one neck strap is also provided.

Abstract: An apparatus and method for resuscitating a patient suffering from cardiac arrest or another condition in which normal circulation has been interrupted. A ventilator is used for delivering a gas mixture to the patient. The ventilator is configured to adjust the partial pressure of CO2 to one or more partial pressures high enough to slow expiration of CO2 from the patient's lungs and thereby maintain a reduced pH in the patient's tissues for a period of time following return of spontaneous circulation.

Abstract: The present invention includes a device and method for relaxing and promoting healing to an individual by synchronization of kinesthetic and aural whole tone sounds.

Abstract: An elongate medical device having an axis comprises an inner liner, a jacket radially outward of the liner, a braid comprising metal embedded in the jacket, a sensor, and at least one wire electrically connected to said sensor. The at least one wire is one of: embedded in the jacket and optionally disposed helically around the braid; extending longitudinally within a tube which extends generally parallel to the device axis and wherein the tube is embedded in the jacket; and disposed within a lumen, wherein the lumen extends longitudinally within the jacket.

Abstract: The apparatus of one embodiment of the present invention is comprised of a flexible sheath instrument, a flexible guide instrument, and a tool. The flexible sheath instrument comprises a first instrument base removably coupleable to an instrument driver and defines a sheath instrument working lumen. The flexible guide instrument comprises a second instrument base removably coupleable to the instrument driver and is threaded through the sheath instrument working lumen. The guide instrument also defines a guide instrument working lumen. The tool is threaded through the guide instrument working lumen. For this embodiment of the apparatus, the sheath instrument and guide instrument are independently controllable relative to each other.