Abstract: A method and apparatus for administering an active agent such as a medicine to a subject, uses an ocular implant such as a punctal plug, to which the active agent has been applied. The implant is installed at the eye of the subject for administering the active agent via tissues of the eye.

Abstract: A navigation apparatus for optically analyzing an inner structure of an optical element and processing that element includes a detection device and a processing device. The detection device has an aperture smaller than 0.25 and the processing device is disposed relative to the analyzed inner structure of the optical element. An apparatus for planning therapy for a human eye includes a dynamic wavefront measurement device for acquiring wavefront data, a diagnostic device for determining geometric parameters of the optical apparatus of the eye, a controller for consistent superposition of the wavefront and geometric data, and an additional controller for planning the most efficient therapeutic laser cutting paths.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: Eyewear is disclosed that can have multiple ventilation states providing different amounts of ventilation through the eyewear. The eyewear can include a lens and a frame. In some embodiments, the lens can be movable with respect to the frame to provide the multiple ventilation states. In some embodiments, the eyewear can include a gasket that removably attaches to the frame. In some embodiments, the gasket can be movable with respect to the frame to provide the multiple ventilation states.

Abstract: An improved hearing protection device intended to be inserted into an external auditory meatus of a user, having a housing structure, a passive tuning element, and a passive, nonlinear acoustic filter. The tuning element and the acoustic filter may be supported in series by the housing structure. The tuning element may be or include a diaphragm, a resonator, or both. The housing structure may support a diaphragm of the tuning element at its circumference, and may provide cavities on both sides of the diaphragm. In some embodiments electronic components are included in the hearing protection device to counteract insertion loss provided by the passive element, and restore natural hearing for low to moderate sound pressure levels, Communications devices may also be incorporated into the hearing protection device.

Abstract: The invention herein relates to a wound dressing product, combining a hydrophobic fabric, which is to be placed towards the wound, and is capable of binding unwanted microorganisms, and a moisture carrying matrix such as a gel or a foam. The product of the invention is ideal for treatment of drier wounds. It protects the wound and reduces the number of pathogenic microorganisms, without using antimicrobial substances and at the same time adds or traps moisture to the wound both supporting the hydrophobic functioning of the pad and healing in general by keeping the wound moist.

Abstract: In the absorbent article package, display element unit that has display elements exhibiting a pattern and/or a mark and non-display element unit that does not have display elements are provided on a package sheet that encloses the absorbent article. A window unit, which is configured to allow the absorbent article packages contained therein to be seen, is formed on one side of a container bag and is configured so that only the non-display element unit can be seen through the window. A container bag display unit that shows the display elements is provided on the one side where the container bag window is provided.

Abstract: A entry and exit assist system for a vehicle has a mounting slot formed within a door of the vehicle. A wheelchair has a set of wheels and a seat coupled to the set of wheels, wherein the set of wheels are one of detachable from or foldable under the wheelchair. A supporting connector is coupled to the wheelchair. The supporting connector slides into and engages the mounting slot holding the wheelchair above a ground area when the set of wheels are one of detached from or folded under the wheelchair. A seatback is slideably mounted on a track in the vehicle. Closing the door with the supporting connector engaging the mounting slot and holding the wheelchair above a ground area positions the wheelchair in the vehicle. The seatback provides back support for a user of the wheelchair.

Abstract: The present invention is directed to a wheeled lifting device that is configured for positioning between an extended configuration and a retracted configuration and adapted for attachment to a wheeled or non-wheeled device. In the extended configuration, the wheeled lifting device is configured to allow for multi-directional movement of the wheeled or non-wheeled device. The wheeled lifting device may include an extension mechanism and at least one multi-directional wheel, where the extension mechanism is configured to move the wheeled lifting device between the retracted configuration and the extended configuration. The extension mechanism can include a mechanical mechanism, a hydraulic mechanism or a pneumatic mechanism.

Abstract: A wheelchair includes a pivotable mechanism. The pivotable mechanism allows for a pivoting movement about an axis defined by an interface between adjacent components. These components may be (a) a seat member and a back member, (b) a seat member and a footrest, (c) a foot rest and a footplate support, (d) a baseplate and a footplate, or (e) a back member and a headrest.

Abstract: According to the present disclosure, a microclimate system includes a topper and an air box. The topper is configured to conduct air along a surface of the topper so that heat and moisture from a patient lying on the topper are drawn away from the surface. The air box includes a blower coupled to the topper to provide air to the topper to be conducted along the surface of the topper. The air box may also include an environmental sensor unit coupled configured to detect environmental information corresponding to the environment around the microclimate system.

Abstract: A lifting column includes first and second lifting column components, one slidably receivable in the other, each having mutually facing guide surfaces. The first lifting column component has first and second openings in its guide surface, and first and second guide components mounted in these openings. Each of the guide components includes an attachment structure that projects into one of the first and second openings and a substantially planar guide section connected to the attachment structure that overlies a guide surface of the first lifting component and that is configured to abut on the guide surface of the second lifting column component. The first and second guide components are configured such that they are in contact with each other when the attachment structures are mounted the openings.

Abstract: A number of patient beds are disclosed. Various caregiver control panels and patient control panels for controlling features and functions of a patient bed are also disclosed. For example, a cart with caregiver control inputs, including hand inputs on a graphical user interface (GUI) and foot inputs, is disclosed. Patient positioning and transfer devices are also disclosed. Various types of in-bed physical therapy devices are also disclosed.

Abstract: A transporter table system for rollably transporting a patient between two support surfaces comprising a transporter table and a surgical table, wherein each table includes a table top, having a plate surface mounted atop with an array of openings, a plurality of rocker arms freely vertically movable within the table top, and an array of rollers rotatably mounted atop the plurality of rocker arms. The transporter system further comprises a locking mechanism for securing the transporter table to the surgical table during use and at least one motor within each of the tables for the purpose of adjusting the height and tilt of plurality of rocker arms and associated table tops.

Abstract: A lift apparatus for lifting a patient comprises a sling bar (60) adapted to have a sling (110) secured thereto, a controller (138) and a status indicator (160) responsive to the controller for indicating the status of at least one parameter associated with the lift apparatus. The associated parameters comprise height, speed, sling securement state, sling compatibility, and fault state.

Abstract: A grossing station for use with performing autopsy, necropsy or pathology procedures comprises a table and an overhead hood connected to a top surface of the table. The grossing station further comprises a blower and ventilation system arranged in the table to move air across the table from a front to rear direction. The grossing station also comprises a trough arranged in an upper surface of the table, wherein the trough receives a plurality of interchangeable grid plates or sinks therein. The grossing station also comprises a first and second panel arranged at the side of the hood in order to create a fume hood for use by the user of the grossing station.

Abstract: A casket comprises a casket shell adapted to receive a deceased, a casket lid closeable on the shell, a casket ornament, and an attachment mechanism. The attachment mechanism has a first portion mounted to a corner of the shell and a second portion mounted to the casket ornament. The first and second portions resiliently cooperate to operably removably attach the casket ornament to the casket shell corner.

Abstract: A spinal therapy apparatus including at least one gripping member whose direction deviates from the transverse direction relative to the spinal column, so that the angle between the gripping member and the midline of the spinal column is less than 90°. A gripping member unit includes preferably two gripping members the angle between the ridges of the gripping members being less than 180°. There is a gap or groove between the gripping members. The gripping member unit also includes a support part, the support part being padded, preferably including two parts and in an inclined position relative to the floor. There is a groove between the gripping member and the support part. The spinal therapy apparatus may also incorporate at least one support handle, which the user can use to move the required part of the spinal column to the ridges of the gripping members.

Abstract: Devices for recognizing and responding to Strabismus and Autism are provided herein. Eye-tracking and software analysis are used to identify adverse visual characteristics of both in real time and compelling visual feedback is used to stimulate correction as those events occur.

Abstract: A deep tissue massage device that includes a compliant cylinder formed of compressible material, the cylinder having an external surface with at least one external ridge pattern formed on the exterior surface of the cylinder. The at least one ridge pattern includes a single ridge circumferentially formed on the exterior surface of the cylinder that has a V-shaped branch portion that extends from one end of the single ridge and joins together at a second end of the single ridge to form two opposing Y-shaped ridges.

Abstract: Embodiments of the invention include methods and devices for increasing blood flow and controlling the temperature of a mammal. The device generally includes collapsible and pliant body elements, capable of expanding from a first volume into an expanded second volume which can then be reduced from the expanded second volume into a pressurized third volume. One or more thermal exchange units can be positioned in the one or more collapsible and pliant body elements. Accordingly, the temperature of the extremity of a mammal can be regulated by providing heating or cooling to the one or more thermal exchange units.

Abstract: A compression device for the foot comprising: a wrap adapted to surround the foot, the wrap comprising at least two bladders which when inflated conform to the shape of the foot to provide compression, the bladders being positioned on the wrap so that a first bladder focuses compression on the heel of the foot and a second bladder focuses compression on the arch of the foot; a channel attached to each bladder for independently delivering fluid to each bladder; and a controller attached to the channels that generates and independently controls the flow of fluid to the bladders.

Abstract: A massage roller has a central spinal recess portion, a circular wall portion on each side of the spinal recess portion, and an outer portion extending outwardly from each of the circular wall portions, the outer portion having a first diameter at or near the circular wall portion, and a second diameter remote from the circular wall portion, the second diameter being larger than the first diameter.

Abstract: Methods, apparatus and compositions are disclosed for collection and transport of biological samples for testing and/or evaluation by a clinical laboratory. In particular, the disclosure relates to the self-collection of such samples by subjects providing the samples. Self-collection is necessary in some situations e.g. where a subject's religion prohibits being touched by a non-family member and subjects at great distance from medical facilities.

Abstract: A packaging system includes a vial with a rim about an upper open end, and a neck between a lower closed end and the rim. The vial contains a pharmaceutical product. A valve is disposed over the open end, and a crimp ring is disposed over the valve with an opening defining an access port. A detachable cap is disposed over the access port. A single tubular label is disposed about the vial, and extends only from a first edge aligned with the closed end to a second edge at the cap. The label has first and second sections separated by a single circumferential perforated boundary aligned with the neck. The first section is backed with an adhesive and attached to the outer vial surface, and extends between the closed end and the boundary. The second section extends at least between the boundary and the cap.

Abstract: A container usable for lyophilization, storage, and reconstitution of medication having only two parts, one of which is a plug component having a flow path terminating in a side outlet port and a second of which is a barrel component. The barrel component has a spiral mixing channel near its distal end in which powder medication is stored and upon reconstitution, yields a gradient concentration. The inner wall of the barrel includes a longitudinal diluent groove. To connect the plug outlet port with the longitudinal diluent groove, the plug or barrel has a 360° distribution groove encircling the plug and connecting to the plug outlet port. Regardless of what rotational orientation the plug has to the barrel, the diluent will always reach the mixing channel.

Abstract: Embodiments generally relate to a pill box adapted for dispensing medication. In one embodiment, the pill box includes a base member, a carousel coupled to the base member and configured to rotate about the base member, one or more compartments, each compartment formed within the carousel and configured to store a single dose of medication with a lid configured to enclose the base and the carousel. The pill box ratchet advancement mechanism includes a resilient member and a stop member configured to facilitate motion of the carousel in a first direction and to restrict motion in a second direction, and a locking component configured to permit a pre-determined displacement of the carousel in the first direction and to limit further displacement in the first direction by locking the carousel.

Abstract: The invention provides an elastomeric expandable container 10 having a first opening 12 adapted to enable the introduction of a comestible fluid 16 under pressure to inflate the same, and a second opening 20 provided in a nipple-like projection 22 extending from said container 10 and adapted for nursing babies, said second opening 20 being closed by valve means 24, and said valve means 24 being opened and closed by the natural nursing actions of the baby to enable fluid 16 to flow under pressure of the inflated container 10 through said nipple 22 and out of the opening 20 thereof.

Abstract: In accordance with the present invention, a variably ergonomic bottle extension system to increase a bottles feeding range comprising a baby bottle (2) having a first articular surface to pivotably conjoin with an elongated extension rod (12) having a second articular surface, wherein conjoining the surfaces creates a joint, so that the bottle (2) can pivot along one or more axes. Whereby conjoining the bottles (2) articular surface with the extension rod's (12) articular surface pivotably extends the bottles feeding range and furthermore, pivotably accommodates a number of feeding positions. Whereby a caretaker can, while cradling an infant, grip the extension rod (12) with their cradling arm or other arm and use the bottle's (2) extended feeding range to feed an infant with their cradling arm or other arm. Whereupon, if a caretaker uses their cradle arm to feed, they can unencumber their other arm for other purposes.

Abstract: Methods and devices for orally administering fluids and medical instrumentation to individuals for the promotion of health are disclosed. An apparatus is described comprising a pacifier configured to hold fluid and configured for sucking. In some embodiments, the apparatus includes a balloon positioned within a cavity of the pacifier. The balloon is configured to facilitate expulsion of the fluid from the cavity and to limit a user's ingestion of air. In other embodiments, the apparatus includes a cartridge or ampoule configured to store a fluid and expel the fluid through the pacifier. Systems are disclosed which include the pacifier apparatus, a known quantity of fluid or powder, and sterile packaging. Other systems are disclosed whereby various attachments, both medical and non-medical, couple to the apparatus. Methods of using and methods of manufacturing are also disclosed.

Abstract: A dental adhesive composition is described comprising a photocurable ionomer, radiopaque metal oxide nanoparticles, a phosphorous-containing acidic monomer, other polymerizable resin components, and a polar solvent. In a favored embodiment, the adhesive composition comprises a photocurable ionomer in an amount up to 15 wt-%; 5 wt-% to 30 wt-% of radiopaque metal oxide nanoparticles that comprise a basic surface (such as zirconia) wherein the nanoparticles comprise an organosilane surface treatment; a phosphorous-containing acidic monomer in an amount up to 10 wt-%; and 10 wt-% to 50 wt-% of solvent comprising water and at least one alcohol, ketone, or mixture thereof.

Abstract: Denture adhesive compositions having good hold and improved taste containing a salt of a copolymer of alkyl vinyl ether-maleic acid or anhydride. Compositions containing from about 25% to about 45%, by weight of the composition, of a salt of a copolymer of alkyl vinyl ether-maleic acid or anhydride containing a cationic salt function containing: i) from about 60% to about 72% cations selected from calcium, strontium, magnesium, or combinations thereof; ii) from 0% to about 10% sodium cations; iii) less than 1% zinc cations; and iv) from about 25% to about 40% of a free acid component; and further containing from about 15% to about 25%, by weight of the composition of a carboxymethyl cellulose having a molecular weight of from about 200,000 to about 1,000,000 daltons; and a carrier. Methods of improving the adhesion of dentures to the oral cavity by applying such compositions to dentures, the oral cavity, or both, and thereafter securing the denture to the ridge or palate of the oral cavity.

Abstract: Addition-fragmentation oligomers of the general formula Z—By-A-(B-A)x-B-A-By—Z, where the A monomers units are derived from a diester or diacid, the B monomer units are derived from a difunctional monomer having functional groups co-reactive and at least one of the A or B monomers comprise a 1-methylene-3,3-dimethylpropyl group.

Abstract: A hair care composition comprising: a crosslinking component comprising an inorganic fluoride; and a conditioning component, wherein the composition has a ratio of crosslinking component to conditioning component in the range of about 10:90 to about 95:5.

Abstract: The invention relates to a composition for dyeing human keratin fibers such as the hair, in foam form, comprising at least one alkaline agent, at least one oxidizing agent, at least one oxidation dye precursor and at least one polycondensate of ethylene oxide and of propylene oxide of structure (I) below: H—(O—CH2—CH2)a(O—CH(CH3)—CH2)b—(O—CH2—CH2)a?—OH, in which a, a? range from 2 to 150, and b ranges from 1 to 100. The invention also relates to a process for dyeing human keratin fibers using this composition. A subject of the invention is also a device for dyeing keratin fibers, comprising the composition of the invention in liquid form and a foam dispenser for delivering the composition in the form of a foam.

Abstract: A cosmetic active principle produced by the hydrolysis of Eucheuma cottonii and including linear galactans, as well as to the use thereof for promoting the protection of the telosome and telomeres of skin cells and thereby preventing and/or controlling skin aging. Also, the cosmetic compositions including the active principle and a cosmetic skincare method.

Abstract: An agent for coloring and/or lightening keratinic fibers, in particular human hair, includes: (a) ammonia in a quantity of 0.40 to 3.0 wt.-%, preferably of 0.50 to 2.4 wt.-%, more preferably of 0.60 to 2.0 wt.-% and especially preferred of 0.62 to 1.75 wt.-%, based on the weight of the agent, (b) one or more alkanolamines from the group of monoethanolamine, 2-amino-2-methylpropanol, and triethanolamine, (c) one or more ethoxylated fatty alcohols having a degree of ethoxylation from 80 to 120, (d) cetyl alcohol and stearyl alcohol in a total quantity of 4 to 8 wt-%, based on the weight of the agent, (e) one or more ethoxylated fatty alcohols having a degree of ethoxylation of 30.

Abstract: The present invention provides a cosmetic exhibiting superior feeling to the touch and a superior uniformity using a novel organopolysiloxane. The cosmetic contains a liquid organopolysiloxane having fluidity at 25° C. and having a crosslinked three-dimensional network structure. The aforementioned liquid organopolysiloxane has a loss factor, tan ?, at a shear frequency of 10 Hz, which is 1 or more.

Abstract: The present invention relates to a make-up cosmetic composition containing MQ silicone resin and propyl silsesquioxane resin, and, more specifically, relates to a make-up cosmetic composition which contains MQ silicone resin and propyl silsesquioxane resin, gives an outstanding moisturizing impression and is free from any pulling phenomenon.

Abstract: The present invention provides a topical formulation and method of use where the formulation comprises macqui berry or a macqui berry extract containing anthocyanins having a very high oxygen radical absorbance capacity (ORAC). The formulation provides the macqui berry in a stabilized form which includes a glucuronide or glycuronide, a photostabilizing agent, encapsulation, or light- and/or air-blocking packaging.

Abstract: Disclosed is a method of topically applying Myriophyllum spicatum extract to skin, the method comprising topically applying a composition comprising Myriophyllum spicatum extract to skin.

Abstract: Disclosed is a composition and methods for its use to reduce the appearance of cellulite and improve skin texture comprising a combination of one or more of Rubus fruticosus extract, Argania spinosa kernel oil, Coleus barbatus extract, glycolic acid, and a mixture of caffeine, escin, and algae extract.

Abstract: Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Abstract: The present invention provides an inhalation-type pharmaceutical composition for Alzheimer's disease and preparation method thereof, comprising a first gas and an atomized medicine. The first gas comprises hydrogen. The gas volume concentration of hydrogen in the inhalation-type pharmaceutical composition is between 2 to 96%. The atomized medicine is selected from a group comprising rivastigmine hydrogen tartrate, donepezil hydrochloride, galantamine hydrobromide, memantine hydrochloride, and any combination thereof. The inhalation-type pharmaceutical composition of the present invention can provide the convenience of taking medicine and removing harmful radicals in the body of the patient through the use of hydrogen while also increases the absorption effect of the medicine for the patient by using an atomized medicine. At the same time, because the use of the small amount of the vaporized pharmaceutical liquid can indirectly reduce the side effects on the user.

Abstract: The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising a phosphodiesterase type 5 inhibitor and/or a salt thereof, and optionally, a hostile biophysical environment and/or a nitric oxide donor. In some cases, the composition may be stabilized using a combination of a stabilization polymer (such as xanthan gum, KELTROL® BT and/or KELTROL® RD), propylene glycol, and a polysorbate surfactant such as Polysorbate 20, which combination unexpectedly provides temperature stability to the composition, e.g., at elevated temperatures such as at least 40° C. (at least about 104° F.), as compared to compositions lacking one or more of these.

Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; in an orally acceptable gel base, the gel base providing controlled release of the mixture of analgesic oils following application to a tooth; together with methods of making and using the same.

Abstract: A rapidly dispersing dosage form is described. The dosage form releases its active ingredients within a period of less than about ninety seconds. These dosage forms exhibit a three-dimensional shape that is retained for adequate storage but is readily dispersed in the presence of excess moisture. Also disclosed are methods of administration of a medicament and a process for the preparation of rapidly dispersing dosage forms.

Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.

Abstract: Kits and compositions for producing an alginate gel are disclosed. The kits and compositions comprise soluble alginate and insoluble alginate/gelling ion particles. Methods for dispensing a self-gelling alginate dispersion are disclosed. The methods comprise forming a dispersion of insoluble alginate/gelling ion particles in a solution containing soluble alginate, and dispensing the dispersion whereby the dispersion forms an alginate gel matrix. The methods may include dispensing the dispersion into the body of an individual. An alginate gel having a thickness of greater than 5 mm and a homogenous alginate matrix network and homogenous alginate gels free of one or more of: sulfates citrates, phosphates, lactatates, EDTA or lipids are disclosed. Implantable devices comprising a homogenous alginate gel coating are disclosed. Methods of improving the viability of pancreatic islets, or other cellular aggregates or tissue, following isolation and during storage and transport are disclosed.

Abstract: The invention relates to a delayed release pharmaceutical composition of mesalamine comprising: a) granules comprising mesalamine or pharmaceutically acceptable salts thereof and a hydrophilic polymer; b) extragranular excipients; wherein the pharmaceutical composition is further coated with a single layer of polymer.