Abstract: Methods, systems, computer programs, circuits and workstations are configured to generate at least one two-dimensional color blood flow map that combines X and Y encoded primary and secondary peak data of 1-dimensional Inverse Fourier Transform images to visually indicate (i) anterior/posterior and right/left directional components of respective feeding arteries using defined colors and (ii) brightness to indicate an amount of blood flow associated with each voxel, with increased brightness associated with increased blood flow.

Abstract: The invention relates to a medical unit comprises a 3D radar array for the detection of positional or movement data of objects in an examination space and a processing unit for the evaluation of the detected data, with the processing unit being connected to the medical unit and to the 3D radar array, and with the evaluated data being used to control the medical unit or for post-processing data acquired by the medical diagnostic or therapeutic unit. The invention also relates to a method for improving examination or treatment workflows with the medical unit, comprising: detecting positional or movement data of objects in the examination space by the 3D radar array; generating control commands for the medical unit based on the detected data; and post-processing image or spectroscopy data received by the medical based on the detected data. The medical unit is a medical diagnostic or therapeutic unit.

Abstract: Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information.

Abstract: A catheter configured for use with a magnetic field-based localization system includes a distributed location sensor that includes a plurality of individual location sensing coils electrically connected in series. The distributed location sensor has an effective magnetic center based on the individual characteristics of each location sensing coil. The effective magnetic center can be located in a space occupied by another structure such as an irrigation fluid delivery tube. The plurality of individual location sensing coils are generally smaller, thereby easing placement, and collectively, when connected in series, output a relatively strong and noise-free signal.

Abstract: The present invention describes a method and apparatus for detecting and quantifying intrinsic positive end-expiratory pressure (PEEPi) of a respiratory patient breathing with the assistance of a ventilator. A processing device receives respiratory airway data from one or more sensors adapted to non-invasively monitor a respiratory patient, calculates from the respiratory airway data two or more parameters that are indicative of or quantify intrinsic positive end-expiratory pressure of the patient, and generates an indication intrinsic positive end-expiratory pressure (PEEPi).

Abstract: Methods and apparatuses for detecting when a subject gets up out of bed or out of chair by detecting changes in body flexion angle with respect to a threshold. Also described herein are systems for monitoring one or more subjects each wearing an angle-sensing unit.

Abstract: An audiologic test apparatus includes: a processing unit configured to conduct a first and second audiologic tests; a first probe connector for connecting a first probe for the first audiologic test; a second probe connector for connecting a second probe for the second audiologic test; and a pump module connected to a first fluid port of the first probe connector with a first fluid channel and to a second fluid port of the second probe connector with a second fluid channel, wherein the pump module in a first operating mode is in fluid communication with the first fluid port, and in a second operating mode is in fluid communication with the second fluid port, the pump module configured to modify pressure in the first fluid channel when in the first operating mode, and to modify pressure in the second fluid channel when in the second operating mode.

Abstract: A system and method are provided for capturing hearing characteristics from self-administered hearing tests, including loudness tolerance levels at different sound frequencies, as an individualized shaped auditory profile for automatically enhancing audio to complement and address as closely as possible an individual's hearing deficits experienced via a particular signal pathway, the signal pathway including the audio device used to administer the test, the sound environment, and the user's hearing capabilities. The user may self-administer a hearing test on a convenient personal apparatus, such as a smartphone. The shaped auditory profile may then be used to produce enhanced sound subsequently transmitted to the individual via the same signal pathway. In certain of its aspects, the invention is useful for any individual seeking an enhanced hearing experience, whether having hearing within normal range or hearing that is impaired.

Abstract: A biosensor system comprises a capillary substrate, conductive electrode, and a plurality of nanoparticles having an enzyme deposited thereon formed in a cavity at one end of the capillary substrate. The substrate may have an optional reinforcing layer (which may be conductive or non-conductive) and optional insulating layer thereon. A cannula having an optional conductive layer, insulating layer, and reference electrode may also form part of the system.

Abstract: An all-solid, single-body unit for calibrating a pulse oximeter that uses probe light beams is provided. A bulk of the unit is substantially composed of a mixture of materials comprising one or more polymer materials that form a flexible solid medium for the bulk of the unit, one or more scattering materials for scattering the probe light beams, and one or more dye materials for attenuating the probe light beams. The flexible solid medium enables a pulsatile rhythmic train of action force received by the unit to be transmitted in the unit during calibrating the pulse oximeter for substantially emulating change of absorbance characteristics of the probe light beams due to pulsing arterial blood. The scattering materials and the dye materials are localized in the flexible solid medium, enabling the unit to be used in calibrating the pulse oximeter without a need for an additional device for further emulation.

Abstract: A blood-sampling tube with a first fluid-receiving chamber for receiving a fluid is described, where the first fluid-receiving chamber may be connected to at least one fluid channel that has a sensor device for measuring at least one biochemical function of the fluid passed through the fluid channel, where the measured biochemical function of the fluid may be read out from the sensor device via a data interface of the blood-sampling tube.

Abstract: A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

Abstract: A dosimeter system for determining radiation exposure including first and second units, where the first unit determines a first quantity indicating influence of a first radiation field, and transmitting the first quantity by the first detecting-unit to the second unit, where the second unit determines second quantity indicative of influence of a second radiation field on biological tissue, third detecting-unit determines a third quantity indicative of an influence of the second radiation field, where the third detecting-unit is of the same type as the first detecting-unit included by the first unit, and determining quantity for adjusting the first quantity on basis of the second quantity by the second detecting-unit and third quantity by the third detecting-unit, adjusting the first quantity so a fourth quantity indicative of an influence of the first radiation field on biological tissue based on the first quantity by the first detecting-unit and adjusting the first quantity.

Abstract: The catheter allows mapping and/or ablation of the area around two or more PV ostia at the same time, with a single placement of a distal section of the catheter having a 2D configuration resembling an infinity or lazy 8 symbol. The catheter has an elongated catheter body, a distal section having at least a flexible elongated member with shape memory, the member being configured to assume a 2D configuration resembling an infinity symbol, and at least one electrode mounted on the member. The 2D configuration resembles a first loop and a second loop, wherein the first and second loops are side-by-side, generally extending in a common plane.

Abstract: A delivery system and method for placing a medical implant, such as for diagnosing, monitoring and/or treating cardiovascular diseases. The delivery system includes a hollow catheter, an anchor coupled to the catheter, and an implant secured within the anchor. The anchor has a base portion with first and second longitudinal ends and a cage therebetween. The anchor further has flexible arms, flexible legs, features for securing the medical implant within the cage of the base portion, and a coupler portion connected to and spaced apart from the second longitudinal end of the base portion. Surfaces of the arms and legs are adapted to clamp the anchor to a wall. The system further includes a pusher wire adapted to cause the anchor to acquire a stowed configuration in which the legs axially extend from the base portion, permitting the anchor to be retrieved after its deployment.

Abstract: Systems, methods and non-transitory computer readable media for imaging. The system includes one or more radiation sources and detectors configured to transmit x-ray radiation towards a subject for imaging a dynamic process in a ROI of the subject and to acquire projection data corresponding to the ROI, respectively. The system also includes a computing device operatively coupled to one or more of the radiation sources and the detectors. The computing device is configured to provide control signals for performing one or more reference scans for acquiring reference data from a plurality of angular positions around the subject and for performing one or more tomosynthesis scans using one or more tomosynthesis trajectories for acquiring tomosynthesis data following the onset of the dynamic process. Additionally, the computing device is configured to reconstruct one or more images representative of the dynamic process using the reference data and/or the tomosynthesis data.

Abstract: An X-ray CT apparatus includes: an X-ray detector in which detecting elements that detect X-rays are arranged in a body-axis direction and a rotation direction; an acquiring unit that acquires signals of the X-rays detected by at least one group of detecting elements which includes a predetermined quantity of detecting elements and in which detecting elements are arranged in at least the rotation direction and that, when reading the signals detected by the detecting elements arranged in the rotation direction from the X-ray detector, sequentially reads the signals at times that vary among the detecting elements arranged in the rotation direction; a correction signal acquiring unit that, in accordance with the signal reading times, acquires correction signals used in a correcting process performed when an image is generated; and an image generating unit that generates the image by applying each correction signal to a corresponding one of the signals.

Abstract: A mammography or tomosynthesis apparatus, comprising a mechanism configured to move a paddle, relative to a detector platform fixed to a main body of the apparatus, to compress a patient's breast against the detector platform to form a surface. The mechanism comprises a post that is mobile relative to the detector platform and/or to the body and configured so that maximum extension of the post relative to the surface follows the movements of the paddle relative to the detector platform.

Abstract: Certain embodiments of the present invention provide for a system and method for assessing the accuracy of a surgical navigation system. The method may include acquiring an X-ray image that captures a surgical instrument. The method may also include segmenting the surgical instrument in the X-ray image. In an embodiment, the segmenting may be performed using edge detection or pattern recognition. The distance between the predicted location of the surgical instrument tip and the actual location of the surgical instrument tip may be computed. The distance between the predicted location of the surgical instrument tip and the actual location of the surgical instrument tip may be compared with a threshold value. If the distance between the predicted location of the surgical instrument tip and the actual location of the surgical instrument tip is greater than the threshold value, the user may be alerted.

Abstract: An apparatus for tracking movement of a foreign object within a subject has an X-ray fluoroscopic system with an X-ray detector and an ultrasound system that has a probe with a position sensor. A display is configured to display a static X-ray image acquired by the X-ray fluoroscopic system and a real-time ultrasound image acquired by the ultrasound system. The X-ray image and the ultrasound image each display at least a portion of the foreign object and at least a portion of surrounding area. A tracking module is configured to track movement of the foreign object within the ultrasound image and the display is further configured to display an indication of the movement of the foreign object on the X-ray image.

Abstract: An imaging system comprises: a plurality of pixels each for converting light, converted from radiation by a conversion unit, into an electrical signal; an extracting unit that extracts, based on an image formed based on output signals from the pixels, a pixel with noise generated by the radiation that has transmitted through the conversion unit to arrive at the pixels; and a correcting unit that performs correction to remove the noise with respect to an output signal from the extracted pixel, wherein the extracting unit extracts the pixel with the noise by performing division between first and second images, the first image being formed based on the output signals from the pixels in accordance with the radiation to the conversion unit during a first period, the second image being formed based on these output signals in accordance with that radiation during a second period after the first period.

Abstract: First and second equipment units are connected to a coupling unit configured with angle and/or position sensors in order to determine thereby, for example, a relative position of a first equipment unit in relation to a second equipment unit. In this manner alignment of the first and second equipment units is expedited.

Abstract: A jig for calibrating an image-guided radiotherapy apparatus is disclosed. The jig includes a ball bearing and a three-axis positioner. Once the ball bearing has been moved to the calculated radiation isocenter of the apparatus, other calibration procedures can be performed by directing light onto the jig.

Abstract: An intravascular measurement device can be used to characterize a stenotic lesion in the body of a patient. In some examples, the intravascular measurement device is inserted into the patient and used to measure a physical dimension (e.g., diameter, cross-sectional area) of a blood vessel having the stenotic lesion during non-hyperemic blood flow. Thereafter, a pharmacologic vasodilator drug is introduced into the body of the patient so as to cause the patient to exhibit hyperemic blood flow rates. The intravascular measurement device may then be used to again measure the physical dimension of the blood vessel having the stenotic lesion, this time during hyperemic blood flow. A comparison between the physical dimension of the blood vessel during non-hyperemic and hyperemic blood flow can be used to characterize the stenotic lesion.

Abstract: According to one embodiment, an internal storage unit stores auxiliary diagnostic indication concerning each of examination items in association with a display position of the auxiliary diagnostic indication in a display area where an ultrasonic image is displayed. An image generation unit generates an ultrasonic image concerning an examination item of a scan target based on an echo signal from an ultrasonic probe. A monitor has a display area. A display control unit controls the monitor so as to display specific auxiliary diagnostic indication, of auxiliary diagnostic indication stored in the storage unit, which is associated with an examination item of the scan target, at a specific display position associated with the specific auxiliary diagnostic indication.

Abstract: An ultrasonic transducer element unit includes a substrate, a first ultrasonic transducer element, and a projecting portion. The substrate includes openings being arranged in an array pattern and a main surface. The first ultrasonic transducer element is configured at a first opening of the openings on the main surface of the substrate and has a first height in a vertical direction from the main surface. The projecting portion is configured not to overlap with the first ultrasonic transducer element in a planar view in a thickness direction of the substrate on the main surface and having a second height which is greater than the first height in the vertical direction.

Abstract: A medical imaging data processing apparatus comprising a data receiving unit for receiving imaging data, a rendering unit for rendering images from the imaging data according to one or more rendering parameters and a selection unit configured to output a plurality of images rendered by the rendering unit. At least one of the plurality of output images is rendered using one or more rendering parameter having a value that is different to the value used to render one or more of the other rendered images. The output images are selectable to select the value of one or more rendering parameters associated with the selected image.

Abstract: Information associated with shear calculation is also displayed in ultrasound shear wave imaging. More information than just a shear wave image is provided for diagnosis. Information about the quality or variables used to determine shear is also displayed. This additional information may assist the user in determining whether the shear information indicates tissue characteristics or unreliable shear calculation.

Abstract: Sensor coupled to the ultrasound probe provides position information related to an ultrasound imaging position in the object. A processor performs first registration between the medical image and the ultrasound image based on the anatomical feature in the ultrasound image and a medical image of the object acquired by imaging modality different from the ultrasound apparatus, obtains first registration information which provides a relationship between a coordinate system of the medical image and a coordinate system of the ultrasound image based on the first registration, performs second registration between the sensor and the medical image based on the position information and the first registration information, and obtains second registration information based on the second registration. A display may display a portion of the medical image corresponding to the ultrasound imaging position based on the second registration information.

Abstract: A container assembly including a shield disposed at least partially within a receiving cavity of a receptacle of a lid is disclosed. The shield provides a physical barrier that at least partially covers and blocks an entrance to the receiving cavity to prevent a patient and/or healthcare worker from needle stick injuries. In one embodiment, the shield is adapted to receive a stopper of a collection tube, and the shield is transitionable between a locked position in which the shield is restrained within an open end of the receptacle, and an unlocked position in which the shield is movable within the receiving cavity of the receptacle.

Abstract: A biopsy device comprises a body, a needle, and a cutter actuation mechanism. The needle extends distally from the body. The cutter actuation mechanism rotates and translates the cutter relative to the body and relative to the needle. The cutter has an overmold presenting a lead screw and a hex portion. The cutter actuation mechanism comprises a first gear disposed about the hex portion of the overmold and a second gear engaged with the lead screw of the overmold by a nut that is integral with the second gear. The cutter actuation mechanism is operable to simultaneously rotate the first gear relative to the body at a first rotational speed and the second gear relative to the body at a second rotational speed. With the lead screw and the nut rotating at different rotational speeds, the lead screw rotates relative to the nut at a third rotational speed.

Abstract: A biopsy device includes a body, a probe cannula, a cutter, a vacuum source, a tissue sample holder, and a flexible tube. The probe cannula extends distally from the body and defines an internal passage with a side aperture. The cutter is translatable relative to the probe cannula to sever a tissue sample received in the probe cannula. The vacuum source is in communication with the cutter. The tissue sample holder includes a vacuum port on the exterior surface to communicate with the vacuum source and a removable portion to hold solid tissue samples. The removable portion is selectively removable from the tissue sample holder and includes a straining member to separate fluids from solids. The flexible tube couples the tissue sample holder with the body such that the tissue sample holder is flexibly spaced away from the body.

Abstract: Methods and devices are provided for performing minimally invasive surgical procedures. In one embodiment, a surgical device is provided that include an elongate shaft having a distal portion configured to be movable between a first configuration in which the distal portion of the shaft is substantially straight or linear and a second configuration in which the distal portion of the shaft is articulated at a compound angle. The shaft's distal portion can include two articulation joints to facilitate formation of the compound angle.

Abstract: A stabilizer for use with a trackable surgical instrument can include a first member, a second member and a retaining member. The first member can have a first annular body portion and a first pair of legs extending therefrom. The first annular body portion can include a plurality of locating slots for engaging a selectively positionable portion of a surgical instrument. The second member can have a second annular body portion and a second pair of legs extending therefrom. The second annular body can engage a drive device of the surgical instrument. The first pair of legs can be telescopically coupled with and adjustable relative to the second pair of legs such that the first member can be axially adjustable relative to the second member. The retaining member can cooperate with at least one leg to retain the first member adjustably coupled to the second member.

Abstract: A hemostatic device includes an injection tube having at least one distal tube opening configured to discharge a first fluid to facilitate sealing the puncture. A guide is adjacent a distal end of the injection tube. The guide includes a cone-shaped portion having an apex oriented towards a distal end of the hemostatic device.

Abstract: A deployment device for bringing a sealing plug into position within a puncture tract or incision, and bringing an anchor into position adjacent a tissue puncture, is provided. The deployment device is designed to facilitate easier positioning of the sealing plug, wherein a separate tamping tool is not required. The sealing plug is held in place on the shaft of the anchor by a structure, for example, a knob or boss. The anchor, anchor shaft, and sealing plug may be made of various biocompatible resorbable materials such that the anchor may resorb very quickly, leaving the tissue or artery lumen clear, and the sealing plug may resorb more slowly, to assist in maintaining hemostasis. The deployment device may include a bypass device which maintains the anchor in either an extended or bent configuration. Further, the anchor may include at least one rib, to provide support to the anchor.

Abstract: The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site.

Abstract: A tissue support device is provided for managing access through tissue. The tissue support device engages the tissue proximate an opening in the tissue and biases the tissue support device to bring the engaged tissue together.

Abstract: Surgical instruments for dissection and retraction, providing suction to remove fluids, smoke and debris at the site of a surgical procedure. A surgical dissector/retractor having a handle and head with a suction channel passing within the dissector/retractor. The dissector/retractor includes a smooth leading edge and a suction port on a top surface of the head.

Abstract: An apparatus can include a first flexible member having first and second ends and a first body extending therebetween that defines a first passage portion. A second flexible member can include first and second ends and a second body extending therebetween that defines a second passage portion. The first end of the first flexible member can pass into and through the second passage portion in a first direction such that the first end extends outside of the second passage portion. The first end of the second flexible member can pass into and through the first passage portion in a second direction such that the first end of the second flexible member extends outside of the first passage portion to form a self-locking adjustable flexible member construct. Applying tension to the first ends can draw the passage portions and corresponding second ends toward each other.

Abstract: A stitching assembly including upper and lower cradles, upper and lower needles, and first and second sutures supported by the upper and lower needles respectively. The cradles moves along a curved path in relation to the carriages between advanced and retracted positions. When each cradle is moved from the retracted position towards the advanced position a stitch loop is formed when the respective needle is retracted. This process is repeated alternating between the first and second cradles with the upper and lower needles passing through the previous stitch loop formed by the other needle before passing through the tissue.

Abstract: A wound closure device for promoting hemostasis includes a polyhedral body comprising a proximal body end portion and a distal body end portion, including a suture channel horizontally extending through the proximal and distal body end portions, the suture channel containing proximal and distal suture channel openings. An actuator system includes a suture engagement member configured to selectively facilitate axial movement or release of one or more sutures through the channel in an open configuration, and to facilitate securement of suture(s) in the channel in a locked configuration. The proximal body end portion includes a face configured to contact a body surface, anchoring the body to the body surface when suture(s) are secured under tension by the engagement member in the locked position. Once the sutures are secured, the device lends itself to hands-free anchoring until hemostasis is achieved. The device and sutures may then be removed that same day, shortly thereafter.

Abstract: An osteosynthesis clip for the cicatrization of bone tissue fragments and an insertion tool for inserting the clip are provided. The clip includes at least two engagement legs extending approximately parallel to one another and including respective distal bridging tips and respective proximal insertion tips to be inserted into the bone tissue fragments; and a connecting bridge coupled to the distal bridging tips of the two engagement legs, the connecting bridge including at least two elongated sections extending along side one another, the elongated sections extending along a non-linear trajectory to form a non-linear deformable region, such as a depression or a dome.

Abstract: The present invention concerns a flexible stapling device (1). More particularly, this invention concerns a flexible endovascular stapling device (1) for an intravascular procedure such as patent foramen ovate closure, which is designed to avoid open heart surgery by permitting the closure of the defect utilizing a stapling means (26) which is positioned by using a flexible shaft/guidewire system.

Abstract: In various forms, a sensor-straightened end effector is disclosed. The sensor-straightened end effector may comprise an end effector coupled to a shaft at an articulation point. The end effector may be articulable at an angle with respect to the shaft. A sensor may be disposed on the sensor-straightened end effector, such as on the shaft or on the end effector. The sensor is configured to detect a gross proximal movement. When detecting a gross proximal movement, the sensor may generate a signal to control a motor to begin a straightening process to straighten the end effector with respect to the shaft.

Abstract: A surgical instrument comprising a handle assembly, and actuation member, an elongated body portion, and a locking mechanism is disclosed. The locking mechanism is disposed in mechanical cooperation with the actuation member, and is configured to substantially prevent at least a partial movement of the actuation member when the elongated body portion is not engaged with a loading unit. The locking mechanism comprises a link, a bushing, and a connecting member. The link is configured for mechanical engagement with a portion of a loading unit. At least a portion of the busing is disposed proximally of at least a portion of the link. At least a portion of the connecting member is disposed proximally of at least a portion of the bushing. Engagement between a loading unit and the elongated body portion causes proximal movement of the link, the bushing, and the connecting member.

Abstract: To economically manufacture a surgical clip applicator for U-shaped or V-shaped clips, which allows secure closure of the clips when applied to tissue structures, in particular, also in the case of double-shank or multiple clips, it is proposed that the applicator comprise a handle portion, a shaft adjoining the handle portion, a clip applying tool arranged at the free end of the shaft, and a clip magazine, the applying tool comprising a mouthpiece with tool jaws for holding a clip during the application and a closing device for transferring the tool jaws from an open, idle position to a closed position, and the mouthpiece being made of a plastic material and being held separately from the closing device on the clip applicator.

Abstract: A shunt rivet for implementation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease.

Abstract: An intraluminal apparatus including a catheter and device is positionable at a junction of afferent and efferent vessels of a bifurcation having an aneurysm. After positioning the device to substantially conform the device to the shape of the junction, the device acts as a scaffolding to inhibit herniation of objects out of the aneurysm and the device permits perfusion to the efferent vessels. Positioning the device may include deployment and optional release from a catheter. Embolic material may be inserted in the aneurysm before or after positioning the device. The device may have a proximal end, a distal end, and a plurality of filaments extending between and coupled at the proximal end and the distal end. The device may include a central filament configured to reshape the device. The distal end of the device may include a covering. The device may be football shaped, pumpkin shaped, or acorn shaped.

Abstract: A delivery system for an occlusion balloon includes a delivery catheter and a balloon releasably detached thereto. The balloon can include a base portion that is threaded onto the end of the delivery catheter. The balloon can include a one-way valve or septum in the base portion, through which a filling needle is inserted into a cavity of the balloon. The balloon can be filled with a fluid to expand the balloon and fix the balloon within the patient's body. The balloon can be filled with a hardening material to assist in fixing the balloon in place and occluding the blood vessel. The balloon can include anchoring structure on its outer surface to assist in the fixing the location of the balloon. The delivery device and needle can be detached and withdrawn from the balloon, allowing the septum to close and seal the balloon, leaving the balloon fixed within the body vessel.