Abstract: A nasal cavity insertion device is provided that includes a tubular main body part, at least one elastically deforming part disposed on the outer peripheral surface of the tubular main body part, and a water soluble holding part. The water soluble holding part holds the elastically deforming part in a diameter-reduced state.

Abstract: A device for receipt in a user's mouth includes a tongue engagement element having a front region, a rear region, and side regions that define an opening for receiving a user's tongue, means for retaining the user's tongue in a forward position, and means for changing the size of the opening. The tongue engagement element is shaped such that when placed in a user's mouth, the rear region extends over the user's tongue and the front region extends under the user's tongue. A method of securing a tongue engagement element in a user's mouth includes moving an expanded tongue engagement element under a front region of a tongue and over a rear region of the tongue, and allowing the tongue engagement element to return toward a non-expanded state. The tongue engagement element acts to resist rearward motion of the tongue.

Abstract: An intrauterine device for applying force to a wall of a uterus to promote contraception without blocking the fallopian tubes may include an elongate member formed of a resilient material and having a default expanded configuration and a spring portion disposed approximately at a midpoint between two ends of the elongate member. The IUD may also include two tissue contact members, one tissue contact member disposed at one of the two ends of the elongate member and the other tissue contact member disposed at the other end. The tissue contact members may generate a laterally directed force against the wall of the uterus when the intrauterine device assumes its default expanded configuration.

Abstract: In some embodiments, an implant delivery device can include a housing defining a housing passageway. A distal end of the housing can flexibly couple to a head that can define a head passageway. Collectively, the housing passageway and the head passageway can define an insertion passageway such that, at least a portion of the insertion passageway is nonlinear. The implant delivery device can include at least one insertion member having a distal end configured to be removably coupled to an implant. The insertion member can be disposed within the housing such that, at least a portion of a proximal end of the insertion member is housed within the housing. The insertion member can be configured to bend, pivot, and/or rotate and move within a portion of the insertion passageway to convey the implant to a target tissue.

Abstract: A method and device for treating neurological disorders involving the application of noninvasive, regional brain thermal stimulation to a region of a patient's head associated with a subject neurological disorder. The brain thermal stimulation method and device alters the brain function in the region of the brain underlying the region of the patient's head to which the brain cooling is applied. The method can also include the steps of adjusting the temperature and timing of the thermal stimulation process to optimize the impact on the subject disorder. The brain thermal stimulation device is comprised of a localized means for cooling or warming a desired region of a patient's brain.

Abstract: A system for altering or maintaining temperatures of objects having a heating/cooling unit having at least one primary fluid line for circulating a heating fluid, a cooling fluid or both through at least one pad in fluid communication with the heating/cooling unit. The heating/cooling unit may accommodate any number of primary fluid lines to correspond to the number of pads utilized or the heating/cooling unit may include at least one flow divider manifold in fluid communication with a primary fluid supply line for channeling a fluid through a plurality of pads.

Abstract: A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device may comprise a penetrable barrier to inject therapeutic agent into the device when implanted in the patient.

Abstract: Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle. Methods for making and using the implants to reduce ocular hypertension and intraocular pressure in a patient are described.

Abstract: The present invention pertains to a cassette capture mechanism for uniting a cassette with a console to prevent jamming or damage to the console and/or cassette. The cassette capture mechanism comprises a cassette receptacle, an axial translation linkage, a first sensor apparatus, and a second sensor apparatus. The cassette receptacle is configured to couple with a cassette having a positioning surface. The axial translation linkage is configured to couple the cassette with the cassette receptacle. The first sensor apparatus is configured to detect alignment of the cassette in a horizontal plane with respect to the cassette receptacle when the cassette is initially coupled with the cassette receptacle; and the second sensor apparatus is configured to detect activation of the first sensor apparatus and detect alignment of the cassette in a vertical plane with respect to the cassette receptacle.

Abstract: A method and apparatus for performing a surgical procedure is provided. The surgical procedure may be a phacoemulsification procedure but other procedures may employ the techniques disclosed. The design includes sensing, within the surgical site, for a material change in fluid flow relative to a predetermined threshold. Upon sensing the fluid flow materially differs from the predetermined threshold, the design temporarily increases aspiration vacuum pressure to the surgical site above a predetermined upper threshold toward a maximum vacuum level. The design applies electrically generated disruptive energy, including but not limited to laser and/or relatively low power ultrasonic energy, to the surgical site from a first point in time measured from when aspiration vacuum pressure is above the predetermined upper threshold to a second point in time where pressure falls below a predetermined lower threshold.

Abstract: The invention refers to a tube configured as an implant for insertion at least at one location into the exposed Schlemm's canal of an eye and which, for example, has been mechanically dilated. The elongated tube insertable into the Schlemm's canal includes a plurality openings that are arranged at the tube in axial direction distanced from each other by ring parts and that are in communication with the trabecular tissue the interior space of the tube and the aqueous humor veins of the episcleral vein system and further includes openings oriented in axial direction at a circular arc shaped segment corresponding to the cross section profile of the tube. To realize the natural trabecular aqueous humor drainage, the tube are inserted into the Schlemm's canal that either the openings in the segment are in communication with the aqueous humor veins or that segment with the openings are associated with the trabecular tissue.

Abstract: Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm's canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm's canal.

Abstract: A microfluidic valve for implantation in an eye of a patient is disclosed. The valve may include a chamber formed between a substrate and a flexible membrane. The valve may also include a boss disposed in the chamber and having a top edge in selective contact with the flexible membrane. The top edge includes a relief portion and a non-relief portion, with the relief portion being structurally arranged so that a pressure required to separate the membrane from the relief portion is less than a pressure required to separate the membrane from the non-relief portion. The valve also may include an inlet extending through the boss and the substrate through which fluid enters the chamber and an outlet configured to allow fluid to exit the chamber. Methods for priming a microfluidic valve are also disclosed.

Abstract: Systems and techniques for laser surgery based on imaging a target tissue by nonlinear scanning are presented. In one implementation, a method for guiding an eye surgery can include the steps of: positioning an eye in relation to an imaging system; creating first scan data by determining a depth of an eye target region at a first set of points along a first arc; creating second scan data by determining a depth of the eye target region at a second set of points along a second arc; determining target region parameters based on the first and second scan data; and adjusting one or more surgical position parameters according to the determined target region parameters.

Abstract: A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss.

Abstract: Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.

Abstract: Dressings, systems, and methods for treating a tissue site on a patient involve allowing liquids from the tissue site or a priming fluid to evaporate and exit the dressing through a liquid-impermeable, vapor-permeable membrane. The dressing is able to process more liquids than would otherwise be possible without evaporation and potentially to create reduced pressure. Other dressings, systems, and methods are disclosed.

Abstract: A reduced pressure treatment appliance is provided for treating a wound on the body of a patient. In some embodiments, the appliance comprises an overlay, which is further comprised of cup members that may be detached or cut away from the overlay so that the overlay can be adjusted in size and shape. Also, in some embodiments, the overlay is further comprised of a pressure venting valve to maintain a predetermined level of reduced pressure at the site of the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the site of the wound in the volume under the overlay. In yet other embodiments, the treatment appliance also includes wound packing means to prevent overgrowth of the wound or to encourage growth of wound tissue into an absorbable matrix comprising the wound packing means. In still other embodiments, a suction bulb may be used to provide a source of reduced pressure to an overlay that covers the wound.

Abstract: An apparatus for stimulating healing of a wound, includes a porous pad adapted to contact a surface of the wound on an affected part of a body. An envelope for receiving the porous pad and the affected part of the body is provided, and the envelope includes a re-sealable opening that permits the wound to be inspected. A connector is fluidly connected to an interior of the envelope and to a source of negative pressure.

Abstract: Apparatus and method for producing absorbent structures with absorbent layers with channel(s) without absorbent material, using a first moving endless surface with specific raised strip(s) and a second moving endless surface with specific mating strip(s).

Abstract: Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a predetermined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device.

Abstract: There is provided a manufacturing method for a sheet-like member associated with an absorbent article, the sheet-like member having a folded-up section which is temporarily-secured in a folded-up state. The method includes: forming the folded-up section by folding up a continuous sheet in a width direction of the continuous sheet, the continuous sheet continuing along a transporting direction, creasing the folded-up section in a folded-up state by pressing continuously the folded-up section along a direction of a fold line of the folded-up section, temporarily-securing the folded-up section in a folded-up state by pressing the folded-up section with a plurality of protrusions that are included in a pressing member, producing the sheet-like member by dividing the continuous sheet with a predetermined pitch in the transporting direction, the continuous sheet having been creased and temporarily-secured, and conveying the produced sheet-like member.

Abstract: To provide an absorbent article that can further reduce leakage of body fluid from an end portion in a longitudinal direction. An elongated shaped absorbent article includes: a top sheet that has a skin contacting surface; a back sheet; and an absorbent core that is disposed between the top sheet and the back sheet, in which a compressed groove is formed on the skin contacting surface; the skin contacting surface has an excretory contact region, a front region, and a rear region; the compressed groove has a pair of first central grooves and a first circular groove that is provided in at least any one of the front region and the rear region; and the first circular groove is arranged at a position overlapping a vertical center line.

Abstract: Breathable, thermoplastic films, laminates, and methods of making films having a basis weight less than or equal to 15 gsm and a water vapor transmission rate of at least about 500 grams H2O/24-hour/m2, wherein the film has a ratio of the MD load at break to the CD load at break of less than about 10, and at least one of a machine-direction notched Elmendorf tear strength of at least about 5 g or a machine-direction notched trapezoidal tear strength of at least about 15 g.

Abstract: The present invention addresses the problem of, in an absorbent article, maintaining at a certain level or lower the difference between the dry flexural rigidity and wet flexural rigidity [(dry flexural rigidity)?(wet flexural rigidity)] at a bonding part. To solve this problem, provided is a sanitary napkin which comprises a top sheet, a back sheet, an absorbent body that is interposed between the top sheet and the back sheet and a compressed part that unites the top sheet and the absorbent body in the thickness direction, wherein: the absorbent body contains a cellulose-based water absorbing fiber and a thermoplastic resin fiber, said thermoplastic resin fiber containing as a monomer component an unsaturated carboxylic acid, an unsaturated carboxylic acid anhydride or a mixture thereof; and the difference between the dry Gurley stiffness and wet Gurley stiffness of the compressed part is maintained at 2.5 mN/12.5 mm or lower.

Abstract: The present invention is method for forming a sandwich structure having a pattern of particulate material enveloped between a carrier material and a cover material. The method allows accurate forming of pre-determined pattern at high production speed. Such a method is particularly useful in the manufacture of disposable absorbent articles, such as baby diapers.

Abstract: Absorbent articles that include elastics in multiple layers are disclosed herein.

Abstract: A composite web comprising a nonwoven layer, wherein the composite web can be incorporated into an absorbent article. A volume of ink is applied to the composite web such that when the composite web is incorporated into the absorbent article, a visual signal is produced. Methods of printing on the composite web are also provided.

Abstract: The present disclosure relates to a substrate that includes one or more human milk oligosaccharides. A disposable absorbent article may include the substrate having one or more human milk oligosaccharides.

Abstract: A novel pressure-sensitive adhesive tape package easy to open and easy in application of an adhesive tape is disclosed. The pressure-sensitive adhesive tape package 10 according to the present invention includes an adhesive tape 14 that accommodates a support 18 and an adhesive agent layer 12 provided on one surface of the support 18, and a release sheet 16 releasably attached to the adhesive agent layer 12. Moreover, the release sheet 16 is folded with the adhesive tape 14, and the adhesive tape 14 is sealed inside of the folded release sheet 16. A plurality of temporary attach portions 50 to 54 spaced from each other is provided in a half of the adhesive agent layer 12 in the adhesive tape 14 to securely expose the half when the release sheet 16 is opened.

Abstract: A system for supporting, lifting, moving, mobilizing, ambulating, and physically rehabilitating a user such as patients in hospitals comprises a chair 100, a frame 200, and a lifting garment 300. The chair 100 has a seat 102 having a front portion 104 and a rear portion 106 and is so constructed that as the seat 102 moves towards a standing position, the rear portion 106 of the seat 102 remains substantially horizontally so a user does not slide out of the seat. The frame 200 is constructed so that the user can enter the frame 200 from either the front side 202 or the rear side 204. The lifting garment 300 is made of a fabric that contracts normal to a direction in which it is pulled for ease in raising a patient in or out of a bed, a chair, or a toilet, to or from a standing position.

Abstract: A combined siderail/over-bed table unit 42 for a bed 20 has a table position in which at least part 62 of the unit overlies a mattress region 48 of the bed thereby serving as an over-bed table and also has a siderail position allowing the unit to serve as a siderail.

Abstract: A patient support apparatus, such as a hospital bed, communicates with an electronic medical record (EMR) system in healthcare facility. The hospital bed includes a patient support structure to support a patient, a graphical user interface coupled to the patient support structure, and control circuitry coupled to the graphical user interface. The graphical user interface displays at least one input that may be used by a caregiver to chart data into an electronic medical record (EMR) of a patient supported by the patient support structure.

Abstract: A knee rehabilitation device is provided which can be used in various stages of knee rehabilitation to facilitate a full range of knee motion and promote joint flexibility following a knee impairment. The device, which can be used by a patient with or without the aid of medical personnel, is simple to use, compact, and is highly adjustable to accommodate different therapy regimens, and different leg sizes. To achieve maximum stretch of affected tissues of a pathologic joint, the device can be used without the need of lower extremity muscle involvement. A first embodiment device is machined or cast from a lightweight structural metal, such as titanium, aluminum or magnesium. The device includes a handle of adjustable length that is rotatably coupled to a parallel-beam leg support. The leg support provides attachment points for multiple adjustable bands that bridge the gap between the parallel beams.

Abstract: Wireless sensor network motes and radar & sensor-based systems receive sensed data, compare it to a predetermined standard and generate a signal to deploy a corresponding response.

Abstract: Unified vision testing and/or training kiosk may utilize display devices and input devices to administer a number of visual testing and/or training tasks to an individual. One or more display devices may provide desired resolution, geometry, and/or touch sensitivity. One or more input devices may receive inputs of different types from different positions relative to a display device. Methods of visual testing and/or training may utilize the one or more display devices, one or more input devices, and/or other types of equipment to evaluate and/or improve the visual abilities of an individual.

Abstract: A sexual novelty is configured to pleasure a user by simulating sexual intercourse. The sexual novelty includes a bladder which can be partially filled with air to create a pressure within the bladder. A plurality of cavities are on the bladder and sufficiently sized to accommodate a user's penis. A pump is attached to the bladder which can provide slight increases in the pressure within the bladder in order to create different levels of pressure. The penis can move in and out of a cavity to simulate sexual intercourse while the pump can be used to change the pressure during simulated sexual intercourse.

Abstract: A system and method of treating hyperactivity of an eyelid closing muscle in a subject includes providing a stimulation system in the subject with the hyperactivity of the eyelid closing muscle, sensing an activity of the eyelid closing muscle, and selectively stimulating eyelid opening muscle(s) or innervating nerves, eyelid opening reflexes, or eyelid opening reflexes in non-muscular tissue, using the stimulation system, without substantially activating the eyelid closing muscle. The system and method evokes eyelid movement in the subject.

Abstract: Devices and methods for attaching a belt cartridge to a belt drive platform. A clip attached to the belt is inserted into a slot in the drive spool of the belt drive platform. The cover plate of the belt cartridge fits into a channel beam in the housing of the belt drive platform, thereby securing the cartridge to the housing. Belt guards, for protecting the cartridge, belt drive platform, patient and rescuer, are rotatably attached to the cover plate and are secured around spindles disposed on the sides of the housing.

Abstract: An integrated columnar structure is connected to hot and cold water supplies. On the structure is separately mounted on eyewash and faucet. In an alternative embodiment a water bubbler can be substituted for the eyewash. Water passageways within the columnar structure separately supply the appropriate temperature water to the faucet and eyewash/bubbler. Valving mounted on the columnar structure, preferably with an angle oriented at an acute angle to the axis of the column, controls the temperature of water supplied to the faucet. Cold, or slightly tempered, water is supplied to the eyewash.

Abstract: An automated system and associated method for storing items comprises a cabinet having at least one refrigerated drawer using a temperature control device and a non-temperature controlled drawer. The drawer design is such that temperature gradients throughout the drawer are minimized. Faraday cages are provided about each drawer to support separate RFID readers to monitor the items in each drawer. The temperature-controlled drawer is insulated so that adjacent non-temperature controlled drawers are not significantly affected by the temperature of the temperature-controlled drawer and they may exist at room temperature. An automatic RFID data detection system determines the temperature requirements of medical items in the temperature-controlled drawer and controls the temperature control device to maintain the required temperature. A temperature logging system for the temperature controlled drawer is provided.

Abstract: A dialysis bag is provided, including a first layer of film and a second layer of film each having a closed end and an opposite outlet end, the layers sealed together about corresponding peripheral edges to define a bag chamber. An outlet assembly is sealingly disposed at the corresponding outlet ends and has a tubular administrative outlet with an inlet and is in fluid communication with the bag chamber. A dimple is formed in at least one of the layers adjacent to the inlet for preventing occlusion as a fluid level decreases in the bag.

Abstract: A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end of an exhaust needle. The exhaust needle has an outlet end within the connector which releases displaced fluid into an absorbent mass which sequesters the fluid to prevent leakage.

Abstract: A portable device for mixing a dilute disinfectant solution comprising a first reservoir comprising a predetermined amount of said disinfectant solution, a chamber which is connected to said first reservoir and which holds a predetermined amount of dilutant, and means for discharging said predetermined amount of said disinfectant solution from said first reservoir into said chamber to be mixed with said predetermined amount of dilutant in said chamber wherein said device provides the dilute disinfectant solution at a fixed dilution determined by the ratio of the predetermined amount of said disinfectant solution to the predetermined amount of dilutant.

Abstract: The present invention relates to a medical device connector for connecting a piercing device (3), with a vial (2) comprising a base member. A plurality of grip members (50), each grip member (50) comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion (61) adapted to temporarily or permanently lock the medical device connector (1) to the vial (2). The base member (30) further comprises a plurality of flanges (40), wherein the proximal ends (P) of the grip members (50) are arranged to the flanges (41, 40). The flanges (40) extend substantially out from the periphery of the base member (30) in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges (40) of the base member (30) forms at least one grip portion.

Abstract: Provided are methods, systems and apparatuses for producing delivery devices, for example, for oral intake of an agent. In the broadest aspect, the method can include assembling one or more layers including one or more materials with an agent or an agent-releasing formulation to form an integrated, for example a laminated, device; folding the integrated delivery device to form a folded integrated delivery device; and at least partially enclosing the fold delivery device to a form suitable for oral delivery. The integrated device can include a first external layer of a first material; a frame of a second material mounted on the first external layer; an agent-releasing formulation housed within the frame; and a second external layer of the first material mounted on the frame.

Abstract: A smart medicine container is provided to secure accesses to a bulk supply of pills stored therein and pills dispensed therein. The medicine container comprises a control unit, a memory, a communication interface unit, a pill-supply housing configured to store a bulk supply of pills, a pill-supply locking means configured to lock access to the pill-supply housing, a dispensing assembly configured to dispense pills from among the bulk supply of pills, and a dispensed-pill housing configured to receive and store dispensed pills, a dispensed-pill locking means configured to lock access to the dispensed-pill housing. The control unit is programmed to irreversibly cause the pill-supply locking means to lock access to the pill-supply housing and irreversibly cause the dispensed-pill locking means to lock access to the dispensed-pill housing when receiving information indicating that the bulk supply of pills should permanently discontinue to be taken by a patient.

Abstract: The current disclosure is directed to a container with a dispensing schedule. In one implementation, the container with a dispensing schedule comprises a bottle with a threaded neck and a complementarily threaded cap having a cylindrical rim and an internal schedule display. An indication on or within the internal schedule display is displayed through an aperture in the cap rim. Features included in the cap and schedule display interoperate to ensure that the displayed indication is advanced when the cap is removed from, and subsequently threaded onto, the bottle container. The displayed indication is relatively large and clear, to facilitate viewing by vision-impaired users, and the indication-advancement mechanism is robust and reliable. In addition, the cap and internal schedule display include features that allow the displayed indication to be set to a particular indication.

Abstract: An article dispensing apparatus includes a carousel and a dispensing face including a dispensing orifice through which the articles are dispensed. The carousel includes plural holding sections for holding the articles to be dispensed and is rotationally movable. A controller controls an actuating unit to apply a force to the carousel to cause the carousel to move rotationally relative to the dispensing face when an instruction to dispense an article is received. When the carousel is moved relatively to the dispensing face so that one of its holding sections having an article therein is aligned with the dispensing orifice, the article is allowed to be dispensed through the dispensing orifice. A detector can detect when an article is within one of the holding sections aligned with the dispensing orifice and when the article is no longer within the one of the holding sections aligned with the dispensing orifice.

Abstract: A silicone baby bottle which is made of silicone which does not generate environmental hormones is disclosed. The silicone baby bottle allows an infant or young child to be safely fed. The silicon baby bottle includes a body part, a nipple, and a coupling member composed of a first coupling ring and a second coupling ring which are screwed with each other to be coupled. The body part and nipple are made of silicone which is a soft material and the coupling member is made of a rigid material so that a coupled structure of the body part and nipple can be tightly sealed. Since only the body part and nipple made of silicone are allowed to come into contact with infant formula and infant's mouth, the infant is not exposed to environmental hormones attributable to synthetic resin.