Abstract: An articulating mechanism for remote manipulation of a surgical or diagnostic tool comprises an elongate shaft having a longitudinal axis and a plurality of axially aligned links located at the distal end of the shaft. The articulating mechanism also includes an actuating element connected to and configured to cause movement of the axially aligned links and a locking mechanism located proximal of the axially aligned links. The locking mechanism including a collar mechanism through which the actuating element extends and a locking member movable between first and second positions. The collar mechanism frictionally impedes motion of the actuating element when the locking member is in the first position and the collar mechanism allows translation of the actuating element when the locking member is in the second position.

Abstract: The present invention provides a catheter clamp assembly having a base and a slide cover. The base has a top, bottom and a body including a slide cover track. The body has internal walls defining a catheter opening extending from the bottom to the top. A catheter channel extends from the catheter opening to a sidewall opening. The slide cover includes a lower surface incorporating a prong to engage a wall defining the catheter opening and to secure a catheter in the catheter channel. The slide cover has a first location providing access to the catheter opening and a second location that clamps a catheter in the catheter channel. Moving the slide cover from its first location contacts a length of catheter extending through the catheter opening to position it in the catheter channel for securement when the slide cover reaches its second location.

Abstract: Apparatus and methods for inserting a medicament into a body cavity are described. The apparatus comprises an elongate tube with a plunger rod therein. The plunger rod has at least one projection which cooperatively interacts or engages with at least one discontinuity on the inside of the elongate tube so that proximal movement of the plunger rod with respect to the elongate tube expels the medicament into the body cavity.

Abstract: A venous access port assembly having a housing base with a discharge port, a septum, and a cap, with an interior reservoir. The housing base is provided with X-ray discernable indicia to identify an attribute of the assembly after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute. Such indicia can be depicted as cutouts through a disc of radiopaque material where the cutouts are in the form of alphabetical letters such as “CT”, or can be a set of discrete elements of radiopaque material, that are affixed along the bottom surface of the housing base or embedded within the thickness of the bottom housing wall.

Abstract: A safety device is described wherein drug delivery systems and methods involve associating unique keys to patients that prevent the interconnection between a drug delivery device and non-complimentary patient key. Medication in a drug delivery device intended for a patient may only be accessed via a particular unique key associated with the intravenous access device of that patient.

Abstract: An iontophoresis patch is equipped with a donor gel and a reference gel which are disposed to contact an external conductor, for example, the skin of a patient and thereby output current from a current-carrying device to the external conductor. The iontophoresis patch includes: a donor portion having the donor gel containing a medical agent to be penetrated into the external conductor; a reference portion having a reference gel, mounted with the current-carrying device on the surface on the side opposite to the reference gel, and disposed on the external conductor apart from the donor portion; and an electrode film for supplying current from the current-carrying device to the donor gel and the reference gel.

Abstract: Anchors for use with implantable medical leads include an elastic body containing one or more rigid bodies that have longitudinal free edges. The longitudinal free edges run from end to end to define full length slots. Partial length slots may also be included within the one or more rigid bodies. The full length and partial length slots allow for deflection of the rigid bodies against the body of an implantable medical lead to hold the anchor in place on the lead. The full length slots allow a blade to pass through and cut a slit in the elastic body which allows the anchor to be removed from the lead.

Abstract: In some examples, a lead identification system includes a first set of first lead indicators and a second set of second lead indicators. Each of the first lead indicators is configured to removably attach to at least one of a first therapy delivery element, a first epidural needle, or a first connector to uniquely identify at least one of the first therapy delivery element, the first epidural needle, or the first connector during implantation of the first therapy delivery element in the patient. Each of the second lead indicators is configured to removably attach to at least one of a second therapy delivery element, a second epidural needle, or a second connector to uniquely identify at least one of the second therapy delivery element, the second epidural needle, or the second connector during implantation of the second therapy delivery element in the patient.

Abstract: A lead anchor including a body having a first end and a second end opposite to the first end is disclosed. The body defines a lead lumen extending from the first to the second end and can receive a lead. The lead anchor also includes a fastening mechanism disposed in the body and in communication with the lead lumen. The fastening mechanism can fasten the received lead to the lead anchor when actuated by a user. The lead anchor also includes tabs(s) extending from the body and tags. Each tag includes an anchor attachment element and a cylindrical implantation element coupled to the anchor attachment element. The anchor attachment element is affixed to one of the tabs. The cylindrical implantation element anchors the lead anchor into patient tissue by insertion of the implantation element into the patient tissue using a needle insertion tool.

Abstract: An implantable electrical line including a lead, wherein the lead includes at least one helically wound electrical conductor. The at least one helically wound electrical conductor is surrounded by a fiber braid, which is formed by at least two fibers or fiber bundles, and wherein the at least two fibers or fiber bundles are interwoven and wound around the electrical conductor in opposite winding directions.

Abstract: A fixation member of an electrode assembly for an implantable medical device includes a tissue engaging portion extending along a circular path, between a piercing distal tip thereof and a fixed end of the member. The circular path extends around a longitudinal axis of the assembly. A helical structure of the assembly, which includes an electrode surface formed thereon and a piercing distal tip, also extends around the longitudinal axis and is located within a perimeter of the circular path. The tissue engaging portion of the fixation member extends from the distal tip thereof in a direction along the circular path that is the same as that in which the helical structure extends from the distal tip thereof. The electrode assembly may include a pair of the fixation members, wherein each tissue engaging portion may extend approximately one half turn along the circular path.

Abstract: An intracardiac capsule comprises a cylindrical body having an atraumatic rounded surface and a helical anchoring screw integral with the cylindrical body. The helical anchoring screw is able to penetrate tissue of a wall of the heart and is configured to provide temporary attachment, in rotation and in translation, of the capsule to an implantation site. The helical anchoring screw surrounds at least a portion of the length of the cylindrical body forming a contact region intended to come into contact with the wall of the cavity of the heart. Over the length of the contact region, the external diameter of the cylindrical body is less than the inner diameter of the helical anchoring screw, so as to leave a free gap there between. The helical anchoring screw is secured to the cylindrical body near the proximal end of the contact region, and extends freely to the opposite distal end.

Abstract: A multichannel clip device and methods of use that facilitate connection of multiple electrical components of a first device and a second device for testing and/or verification are provided herein. Such multichannel clip devices can include a spring-loaded clip having multiple electrical contacts for coupling with a contact portion of a first device and which are connected to a proximal connector through a flexible stimulation cable. The contacts can be included within a neurostimulation lead connector and the proximal connector adapted to couple with standard connectors on a clinician programmer, each contact being coupled to a corresponding contact of the proximal connector to define multiple separate channels.

Abstract: A method of training an individual includes receiving data indicative of a training suitability state of an individual upon a tiltable support platform, and commanding electrical stimulation of a spinal reflex pathway innervating a muscle in the individual, responsive to the data, and such that the muscle reflexively contracts to tilt the support platform. A value indicative of an amplitude of the reflexive contraction is electronically recorded.

Abstract: A hybrid method is provided for modulating upper airway function in a subject. The method includes applying first and second therapy signals to the subject to modulate at least one extrinsic laryngeal muscle and at least one intrinsic laryngeal muscle to synergistically control laryngeal motion and vocal fold movement, respectively.

Abstract: A medical lead is configured to be implanted into a patient's body and comprises a lead body, and an electrode coupled to the lead body. The electrode comprises a first section configured to contact the patient's body, and a second section capacitively coupled to the first section and configured to be electrically coupled to the patient's body.

Abstract: The system includes five components: (1) a sensor array, (2) a processor, (3) a transmitter, (4) a receiver-stimulator, and (5) an implantable electrode array. The olfactory implant system generates odor fingerprints by detecting odors with an array of chemical sensors and then transmitting variable spatio-temporal stimulation patterns for an electrode array with electrode stimulating points positioned at different locations in the olfactory cortex (e.g., stimulating the olfactory bulb). Different patterns of activity in the olfactory cortex are thereby generated which mimic the sense of smell in a subject. Once trained the system should be usable by a subject to detect or correctly identify one or more odors.

Abstract: An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body has a programmable signal generator that can generate the signals based on stored signal parameters without any intervention from a processor that controls the overall operation of the IPG. While the signal generator is generating the signals the processor can be in a standby mode to substantially save battery power.

Abstract: Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator are disclosed. A representative system includes a signal generator and a computer-readable medium that, for first and second signals, increases and decreases an amplitude of the signal over multiple steps from a baseline amplitude at which the patient has a baseline response. At individual step increases and decreases, the system receives a pain score based on the patient's response. The instructions compare the pain scores for the two signals and determine one of the signals for additional therapy to the patient, based on the pain scores and an expected energy consumption of the signals.

Abstract: The present disclosure relates to a method for determining stimulation parameters for a neuroprosthetic device performed by a processor of the device. Based on (i) a desired spatial pattern of neural activity, the processor determines stimulation parameters for an array of electrodes of the neuroprosthetic device. The processor determines the stimulation parameters such that a difference between (i) the desired spatial pattern of neural activity and (ii) an estimated spatial pattern of neural activity is optimised. The estimated spatial pattern of neural activity is an estimate of a response of a target neural tissue to being stimulated by the neuroprosthetic device based on the stimulation parameters. This method allows higher resolution stimulation and allows electrode arrays with higher electrode density to be usefully employed.

Abstract: A system and method using a plurality of electrodes. An immediate electrode configuration is defined, electrical energy is conveyed to the electrodes in accordance with the immediate electrode configuration, a final electrode configuration is defined, a series of intermediate electrode configurations is defined using a heuristic set of rules based on the immediate electrode configuration and the final electrode configuration, electrical energy is conveyed to the electrodes in accordance with the series of intermediate electrode configurations, and electrical energy is conveyed to the electrodes in accordance with the subsequent electrode configuration.

Abstract: An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body includes an electrode driver for each electrode, which adjusts the amplitude of the timing signals and output an output current corresponding to the adjusted signals for transmission to the associated electrode so as to enable independent amplitude control of the stimulation signals for each stimulation pattern channel.

Abstract: An implantable cardiac therapy device having a heart assist pump, a stimulation unit, and a control unit. The heart assist pump is designed to be connected to a ventricle of a heart and an associated artery, and is designed to pump blood from a particular ventricle into an associated artery, thereby supporting the particular ventricle. The stimulation unit is designed to electrically stimulate a heart contraction, and the control unit is designed to control the heart assist pump and the stimulation unit in such a way that the stimulation unit induces synchronized motions of cardiac contraction while the heart assist pump operates in a ventricle-supporting manner.

Abstract: A system for treating soft tissue of a patient. The system includes a treatment head and a computer portion. The treatment head includes a probe and an electrode operably coupled to the probe. The probe and electrode are configured to respectively deliver a mechanical force impulse and an electrical stimulation to the soft tissue when placed in operable contact with the soft tissue. The computer portion includes a CPU and is configured to coordinate the delivery of the mechanical force impulse and electrical stimulation relative to each other. The system is configured to sense a shockwave in the soft tissue of the patient, the shockwave resulting from the mechanical force impulse delivered to the soft tissue via the probe. The system is also configured to analyze a characteristic of the sensed shockwave and configure the electrical stimulation to be delivered to the soft tissue via the electrode based on the characteristic analysis of the sensed shockwave.

Abstract: An example of a method embodiment may include receiving a user programmable neural stimulation (NS) dose for an intermittent neural stimulation (INS) therapy, and delivering the INS therapy with the user programmable NS dose to an autonomic neural target of a patient. Delivering the INS therapy may include delivering NS bursts, and delivering the NS bursts may include delivering a number of NS pulses per cardiac cycle during a portion of the cardiac cycles and not delivering NS pulses during a remaining portion of the cardiac cycles. The method may further include sensing cardiac events within the cardiac cycles, and controlling delivery of the user programmable NS dose of INS therapy using the sensed cardiac events to time delivery of the number of NS pulses per cardiac cycle to provide the user programmable NS dose. The user programmable NS dose may determine the number of NS pulses per cardiac cycle.

Abstract: Methods and apparatuses for amplitude modulation of all or a portion of an ensemble waveform to modify a user's cognitive state by transdermal electrical stimulation (TES). An ensemble current waveform may include a sequence of component biphasic current waveforms in which one or more parameters (such as frequency, current amplitude, percent duty cycle, and percent charge imbalance) vary between sequential component waveforms. These ensemble waveforms may be specifically configured to evoke a particular cognitive state when applied by TES. In particular, described herein are methods for applying amplitude modulation to all or a sub-set of the component waveforms in the ensemble waveform which may dramatically enhance the efficiency and effectiveness of the TES. Also described herein are methods and apparatuses for applying amplitude modulation to all or a portion of an ensemble waveform without truncating pulses of the component waveforms forming the ensemble waveform.

Abstract: An apparatus configured to be placed about an implantable medical device having a face with a geometric center offset from a center of a recharge coil of the device includes first and second opposing major exterior surfaces, and a continuous exterior side surface joining the first and second opposing major exterior surfaces. A cavity is defined between, and an opening is formed by, the first and second major surfaces and the continuous side surface. The opening is in communication with the cavity and is configured to allow the device to access the cavity. An asymmetric region, adjacent to the cavity, is formed between a portion of the first and second major surfaces and the continuous side surface. The asymmetric region is configured to shift the geometric center of the combined apparatus and device, when the device is received in the cavity, towards the center of the recharge coil.

Abstract: A photovoltaic device including a CIGS photovoltaic module having a so-called top surface, intended to be exposed to light radiation; and a light emitting diode emitting light at a wavelength of less than 600 nm and transparent to radiation in the near infrared, attached to the top surface of the photovoltaic module. A photovoltaic generation system having: at least one such photovoltaic device; a system of switches to selectively connect the photovoltaic module to the light emitting diode or to a terminal supplying an external load; and a control circuit for controlling the system of switches. An electrical system having: such a photovoltaic generation system; a battery connected to the supply terminal; and at least one electronic circuit connected to the battery in order to be powered. An implantable medical device having such an electronic system.

Abstract: A notebook, laptop computer or tablet computer having an automated external defibrillator (AED) capability, and methods of utilizing the notebook, laptop computer or tablet computer defibrillator to treat victims of sudden cardiac arrest. Kits and methods for converting, adapting or retrofitting a common notebook, laptop computer and tablet computer to enable each to be used as an AED to treat victims of sudden cardiac arrest. A kit including an adjustable case for receiving, encompassing, adapting and converting a common notebook, laptop computer or tablet computer to enable each to be used as an AED. A kit including a slave automated external defibrillator (AED) that is joined to a common notebook, laptop computer or tablet computer to adapt, convert and enable each to be used as an AED.

Abstract: A method is disclosed of providing photo-chrono-therapy to a wound site in a human or animal subject, the method including: determining or receiving subject circadian and/or ultradian cycle information indicative of a biological rhythm(s) of the subject; and based on the subject cycle information, delivering a photo-chrono-dose of infrared treatment light to the wound site with wavelengths within at least one infrared wavelength range and having a dosimetry configured to promote healing at the wound site.

Abstract: An optical therapeutic apparatus includes an ear shield for covering a wearer's ear, which has a plurality of acupuncture points; a hanging member including a connection portion connected to the ear shield; and a plurality of light emitters disposed within an interior portion of the ear shield in array manner to face the plurality of acupuncture points respectively. The plurality of light emitters includes a plurality of acupoint-stimulation elements, each corresponding to a respective one of the acupuncture points, at least two sets of the acupoint-stimulation elements are capable of emitting stimulation light beams at different time intervals.

Abstract: Provided herein are silk fibroin-based photothermal elements and uses thereof. The silk fibroin-based photothermal elements comprise a plurality of plasmonic nanoparticle distributed in a silk fibroin matrix, and can generate heat when the plasmonic nanoparticles are exposed to electromagnetic radiation. The silk fibroin-based photothermal elements can be adapted to be conformable and biodegradable, and can further be integrated with various electronic components, such as a thermo-electric device for conversion of heat into electricity. The invention is useful for various in vivo applications, such as photothermal therapy, controlled drug-delivery devices or wireless powering of implanted micro-devices.

Abstract: A radiation beam, for example a therapeutic radiation beam such as an IMRT or VMAT X-ray beam is monitored using a Monolithic Active Pixel Sensor (MAPS) detector. Photons of the radiation beam can interact with the MAPS detector, and the radiation beam configuration can be estimated from the determined positions of the interactions. The detector is made sufficiently thin that it interacts only very weakly with the X-ray photons. For example, less than 1 in 103 of the X-ray photons might interact with the detector. Hence, the disturbance to the X-ray beam is negligible.

Abstract: A device for treatment of an ocular pathology characterized in that it comprises at least one eye ring (1) wherein the proximal end of said eye ring (1) is suitable to be applied onto the globe and a generator (2,17) to generate ultrasound beam fixed on the distal end of the eye ring (1), the generator to generate ultrasound beam presenting a concave segment shape conformed along a single curvature corresponding to a single direction wherein the concavity is designed to be tuned towards the eyeglobe.

Abstract: The present invention relates to a nail polish composition, comprising at least one high gloss film forming agent chosen from an esterified styrene maleic anhydride copolymer, a non-esterified styrene maleic anhydride copolymer and mixtures thereof, at least one co-film forming agent chosen from an epoxy resin, optionally, at least one plasticizer, at least one solvent, and optionally, at least one colorant, wherein the composition does not require use of nitrocellulose and can be used to makeup or protect nails. Such compositions impart high gloss, good adhesion and long wear properties.

Abstract: The invention provides methods for encapsulating nanometric particles inside of micro-sized crystals. An exemplary embodiment involves crystallizing a solution including nanometric particles, a micelle-forming material, a nonpolar dispersant for the micelle-forming material and a crystal-forming material to form crystal-encapsulated nanometric particles. Also provided are compositions or materials which include or are formed using the crystal encapsulated nanoparticles, such compositions and materials can include propellants, cosmetics, composite structures, energetics, and pharmaceutical compositions/materials.

Abstract: An assisted-rescue and personal evacuation system preferably includes a deployment bag, an equipment tether, a stop tether, a flexible anchor strap, a descender system, at least two carabiners and a rescue hitch system. The deployment bag includes a bag portion, an end flap, a rope protector and a pair of snap hooks. The equipment tether includes a tether strap and a tether loop. The tether loop is used to retain all of the rescue components. The stop tether preferably includes a stop body, a first stop carabiner and a second stop carabiner. The descender system preferably includes a rescue rope, a descender unit, a rope carabiner and a descender carabiner. The rescue rope is inserted through the descender unit. The rescue hitch system includes a hitch strap, a micro rope grab and a hitch carabiner. A micro haul device provides a 6:1 mechanical advantage for self or assisted rescue.

Abstract: A handheld forcible entry device includes a tubular housing. An input drive shaft is rotationally assembled to the housing, wherein the input shaft rotates about an axis perpendicular to a longitudinal axis of the housing. A helical pressure applicating lead screw is rotationally assembled to the housing, wherein the lead screw rotates about an axis parallel to the housing longitudinal axis. The input shaft and lead screw are rotationally synchronized by a bevel gear set. A pressure applicator is threadably engaged with a helical threaded segment integrated in the lead screw. Rotation of the threading advances or retracts the pressure applicator from a stationary wedge plate. The separation of the pressure applicator and the stationary wedge plate separates a locked member from the associated frame, thus forcibly opening the locked member. The input shaft can be operated using a manually applied rotation or power applied rotation.

Abstract: The invention relates to a spreader tip (32) for replaceable attachment to two pincer-like co-operating spreader arms (4) of a rescue tool (1). Mounted on a working face (35) of the spreader tip (32) is at least one insert element (39) which protrudes from and has different material properties in comparison with the spreader tip (32).

Abstract: A container for storing oxygen under pressure is disclosed that includes a chamber adapted to be worn around a user's waist and adapted for supplying oxygen to the user; the chamber defining a volume to contain oxygen under pressure; wherein the chamber is defined by a central portion extending between opposite side portions; wherein each of the opposite side portions has a height greater than a maximum height of the central portion that further defines a void between the side portions and above the central portion; and wherein the chamber is further defined by an exterior surface of the chamber adjacent the user.

Abstract: Speech enhancement apparatus and respirator masks including speech enhancement apparatus, as well as methods of enhancing speech transmission for the wearer of a respirator mask are described herein. In one or more embodiments, the speech enhancement apparatus and methods described herein detect acoustic energy within a first frequency range in the clean air envelope of a respirator mask and deliver compensating acoustic energy outside of the clean air envelope using a speaker. The compensating acoustic energy is, in one or more embodiments, delivered in one or more predetermined attenuated frequency ranges that cover less than all of the detected first frequency range. In one or more embodiments, the compensating acoustic energy may be delivered with an attenuated amplitude profile that uniform or that is non-uniform over the one or more attenuated frequency ranges.

Abstract: A respiratory mask body defining a first chamber and a second chamber is provided. In an exemplary embodiment, the mask body includes one or more inlet ports adapted to receive one or more breathing air source components in communication with the first chamber and a fluid intake communication component allows communication of air from the first chamber to the second chamber during inhalation by a wearer.

Abstract: An entry/exit gate assembly for a shuttle based fall protection system is provided. The entry/exit gate assembly includes a rail, a gate and a gate manipulation member. The rail has at least one entry/exit cutaway section. The gate is slidably engaged with the rail and the gate manipulation member coupled to selectively lock the gate in a static position in relation with the rail to block access to the at least one entry/exit cutaway section.

Abstract: Methods and/or apparatuses having a conduit with at least one length of conductive metal wire therein along with a length of non-conductive wire therein. The length of non-conductive wire includes a heat-expandable firestop insulator material. Upon reaching a pre-defined temperature corresponding to that of a fire, the non-conductive wire expands to fill a length of the conduit. Alternatively, the firestop insulator material may be disposed in the void within the conduit that exists outside of the conductors. The expansion of the material prevents the spread of fire along the length of the conduit.

Abstract: An automatic stovetop fire suppressor providing a gradual release of a fire suppressing agent in a desired distribution pattern and method of gradual and spatial agent release are provided herein. A plastic cone shaped lid seals on the bottom of a can and forms a closed container. The closed container is filled with a fire suppressing agent. An initiator charge breaks a designed breaking point of a reduced horizontal cross sectional area when fuse activated. The bottom lid drops down exposing a radial opening. Fire suppressing agent flows out of the radial opening, suppressing a stovetop fire with minimal or no splashing of cooking oil. An initiator housing is affixed to a top wall of the can and serves as the welding point for securing the plastic lid. A travel limiting member attached to the bottom lid catches on a shoulder of the initiator housing to limit the radial opening height.

Abstract: A data center includes a plurality of racks on a floor and one or more fire suppression systems coupled to at least some of the racks. The fire suppression systems include reservoirs mounted on the racks, a fire suppression material in the reservoir, and one or more material dispensing devices coupled to the reservoir. The material dispensing devices may dispense fire suppression material onto or into the racks in response to a fire condition.

Abstract: The invention provides a novel bentonite-fiberglass fire blanket, comprising: bentonite and fiberglass and an optional mesh fabric, such as cheesecloth.

Abstract: A sprinkler head removal is disclosed. The sprinkler head remover comprises a tip portion having a width, a shaft having a first end and a second end; and, a handle having a first end and a second end. The tip portion releaseably connects to a sprinkler socket of a sprinkler head. The tip portion attaches to the first end of the shaft. The handle attaches to the second end of the shaft. The width of the tip portion varies according to an internal diameter of the sprinkler socket.

Abstract: A fitness device for fully suspending a user in air includes at least four holds, at least four strap segments, and at least one attachment member. Each hold is configured to allow a user to interface with a hand or a foot. The four holds are configured to allow a single user to concurrently interface the four holds with a separate hand or foot. At least one strap segment is adjustable in length between the corresponding hold and a suspension point. The strap segments are configured to move independently of each other strap segment. The at least one attachment member is configured to attach to a corresponding mounting support structure to enable a user to fully suspend the user's body from a ground surface by contact with the holds.

Abstract: An exercise machine support system for providing increased versatility including inclination or declination of an exercise surface, a reduction in the overall length and width of the exercise machine, and an enhanced user interface which reduces the risk of injury. The exercise machine support system generally includes a cantilevered exercise machine which is adapted to have a variable angle of incline or decline with respect to a horizontal ground surface. The exercise machine will generally include a base and a support which extends between the base and the exercise machine. The upper end of the support is connected to the exercise machine by a first pivot such that the exercise machine pivots about the support. An adjustment device may be utilized to pivot the exercise machine and thus adjust its angle of incline. Various types of adjustment devices are disclosed, including an actuator, ratchet-and-pawl, gears, and cam.