Patents Issued in January 26, 2017
  • Publication number: 20170021056
    Abstract: Provided herein are compositions comprising aligned peptide amphiphile biomaterials, methods of generating such alignment, and their use in nerve repair applications. In particular, peptide amphiphile nanofibers are aligned using a screen extrusion method, and find use in the repair of peripheral nerve injuries.
    Type: Application
    Filed: July 20, 2016
    Publication date: January 26, 2017
    Inventors: Samuel I. Stupp, Mark T. McClendon, Reza Jarrahy, Akishige Hokugo
  • Publication number: 20170021057
    Abstract: Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and optionally including proteins. In one aspect, hyaluronic acid-based compositions described herein include zero-length cross-linked moieties and optionally at least one active agent. The present hyaluronic acid-based compositions have enhanced flow characteristics, hardness, and persistence compared to known hyaluronic acid-based compositions. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Inventors: Karina Heredia Guillen, Ahmet Tezel
  • Publication number: 20170021058
    Abstract: A composition including delipidated, decellularized adipose tissue and delipidated, decellularized fascial tissue is provided. The composition may further include exogenous tissuegenic cells, an exogenous growth-inductive substance, and/or a carrier. The composition is suitable for implantation into a living body in plastic surgery procedures, including reconstructive or cosmetic surgery procedures, wound care procedures or other procedures of regenerative medicine. A method of preparing an acellular soft tissue-derived matrix from adipose tissue and fascial tissue is also provided.
    Type: Application
    Filed: July 22, 2016
    Publication date: January 26, 2017
    Applicant: MUSCULOSKELETAL TRANSPLANT FOUNDATION
    Inventors: Yen-Chen Huang, Asia Ivery, Bryan Choi, Benjamin Schilling, Manh-Dan Ngo, Evangelia Chnari, Todd Nilsen
  • Publication number: 20170021059
    Abstract: A process for preparing decellularized isolated bone tissue samples, comprises the steps of a) providing an isolated bone tissue sample, b) treating said sample by immersions in: a solution comprising at least one chelating agent, a solution comprising at least one anionic detergent, a solution comprising at least one non-ionic detergent, a solution comprising at least one enzyme, a solution comprising at least one antibiotic. Decellularized bone tissue samples as obtainable by a process according to the invention can be used as grafts.
    Type: Application
    Filed: May 17, 2016
    Publication date: January 26, 2017
    Inventor: Ilyas Inci
  • Publication number: 20170021060
    Abstract: A method of making a shape memory polymer (SMP) tissue scaffold includes forming a salt template and adding a macromer solution to the salt template. The macromer solution may include a photoinitiator solution. The method includes drying the SMP scaffold and leaching salt from the SMP scaffold. A coating is then applied to the SMP scaffold. The coating may be applied either before or after heating the SMP scaffold.
    Type: Application
    Filed: July 24, 2016
    Publication date: January 26, 2017
    Inventors: Melissa A. Grunlan, Dawei Zhang, Cody A. Schoener, William B. Saunders
  • Publication number: 20170021061
    Abstract: Methods of post-loading ceramic particles with antimicrobial metal cations are disclosed. In certain embodiments, the post-loaded particles are zeolites, wherein the zeolites have been incorporated into a resin and the combination is used as an implantable device. In certain embodiments, the polymer is a thermoplastic polymer such as polyaryletheretherketone (PEEK). In certain embodiments, the source of antimicrobial activity includes ion-exchangeable cations contained in a zeolite. In certain embodiments, disclosed are methods of imparting antimicrobial activity to devices by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in the device.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Inventors: Joseph J. Crudden, Derrick Johns
  • Publication number: 20170021062
    Abstract: A method for producing an implant, such as an intraluminal endoprosthesis, the method including producing a melt with a material composition of iron, sulfur at a concentration of more than 0.2% by weight and not more than 1% by weight, and at least one element selected from the group consisting of calcium, manganese and magnesium; producing a slab by cooling the melt in a mold at a predetermined cooling rate to produce a semi-finished part; and post-processing the semi-finished part to form the desired shape of the implant body.
    Type: Application
    Filed: October 3, 2016
    Publication date: January 26, 2017
    Inventor: Ullrich Bayer
  • Publication number: 20170021063
    Abstract: An air-permeable guard adapted to attach to a covering, the air permeable guard comprising a plurality of layers attached together to create one or more compartments. The guard further comprises at least one agent stored in the one or more compartments wherein the at least one agent may be a counteracting agent, a masking agent or a disinfectant agent. The masking agent may be coffee, oil and self encapsulated oil beadlet. The counteracting agent may be activated charcoal, sodium bicarbonate, zeolite, diatomaceous earth, silica gel and bentonite clay. The disinfectant agent may be a water based coating containing a cationic siloxane. In another embodiment of the invention the compartments may store the agents in a portion of the guard that is adapted to come in contact with the wearer's nostrils.
    Type: Application
    Filed: June 30, 2016
    Publication date: January 26, 2017
    Inventors: MARIE ANGELA BONTIGAO, DAVID EMERY
  • Publication number: 20170021064
    Abstract: A device and a method of manufacturing an implantable medical device, such as a stent, are described herein. The device includes a metallic region composed of a bioerodable metal and a polymer region composed of a biodegradable polymer contacting the metallic region. The metallic region may erode at a different rate when exposed to bodily fluids than the polymer region when exposed to bodily fluids. In certain embodiments, the polymer region is an outer layer and the metallic region is an inner layer of the device.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Inventors: David C. Gale, Bin Huang, John M. Capek, Dehnad Houdin
  • Publication number: 20170021065
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n-X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Application
    Filed: July 18, 2016
    Publication date: January 26, 2017
    Inventors: Ronald E. Betts, John Dang Nguyen
  • Publication number: 20170021066
    Abstract: A harvesting cannula, including a plurality of ports configured and positioned to improve performance as compared to existing harvesting devices, according to various embodiments, is described herein.
    Type: Application
    Filed: February 26, 2016
    Publication date: January 26, 2017
    Inventor: Marcos Sforza
  • Publication number: 20170021067
    Abstract: A device for removing fluid from a body, the device comprising an array of microneedles and a housing; the array of microneedles being disposed within the housing and the housing defining a chamber. The microneedles are moveable between a disengaged position and an engaged position where, in use in the engaged position, the microneedles penetrate the surface of a body. The chamber is adapted to surround the surface of the body through which the microneedles penetrate when in the engaged position. The chamber is configured for connection to a vacuum device such that negative pressure can be applied to the chamber.
    Type: Application
    Filed: January 23, 2015
    Publication date: January 26, 2017
    Inventors: Simon Todd, Ian Middleton
  • Publication number: 20170021068
    Abstract: Systems, methods, and apparatus are provided for containing and measuring a fluid in a reservoir. A sensing reservoir comprises a reservoir comprising an opening and a wall, the opening configured to allow passage of the fluid in and out of the reservoir, and the wall defining a chamber configured to contain the fluid. The sensing reservoir further comprises a fluid sensing unit coupled to the sensing reservoir, the fluid sensing unit configured to generate measurement data indicative of a volume of the fluid contained in the reservoir.
    Type: Application
    Filed: April 8, 2016
    Publication date: January 26, 2017
    Inventors: Nathaniel Gaskin, Jeffery B. Alvarez, Janica B. Alvarez
  • Publication number: 20170021069
    Abstract: Blood pump devices having improved rotor design are provided herein. Such blood pump devices include rotors having cantilevered support through a sealed mechanical bearing disposed outside a blood flow path of the device so as to avoid thrombus formation caused by blood contact with the bearing. The bearing means can be rotatably coupled with a proximal portion of the rotor shaft extending outside the fluid path, while a stator drives rotation of the rotor shaft so that one or more rotor blades on a distal portion of the rotor force blood flow through the device. The bearing means may include one or more radial bearings on a proximal portion of the rotor shaft that are isolated from the blood flow path by one or more rotary seals.
    Type: Application
    Filed: July 21, 2016
    Publication date: January 26, 2017
    Inventor: William V. Hodges
  • Publication number: 20170021070
    Abstract: A pressure differential across a blood pump and/or a flow rate of blood pumped by the blood pump is estimated based at least in part on impeller thrust load. A blood pump for a circulation assist system includes a housing forming a blood flow channel, an impeller, one or more support members coupled to the housing, a sensor, and a controller operatively coupled with the sensor. At least one of the one or more support members react a thrust load applied to the impeller by blood impelled through the blood flow channel by the impeller. The sensor generates output indicative of the magnitude of the thrust load. The controller is configured to process the sensor output to estimate at least one of a pressure differential across the blood pump and a flow rate of blood pumped by the blood pump.
    Type: Application
    Filed: July 18, 2016
    Publication date: January 26, 2017
    Inventor: Ethan Falk Petersen
  • Publication number: 20170021071
    Abstract: Methods for estimating flow rate in a blood circulation assist system employ impeller eccentricity. A method includes magnetically rotating an impeller within a blood flow channel of a blood pump. The impeller is levitated within the blood flow channel transverse to the impeller axis of rotation. A rotational speed for the impeller is determined. At least one impeller transverse position parameter is determined. The at least one impeller transverse position parameter is based on at least one of (1) an amount of a bearing current that is used to levitate the impeller transverse to the impeller axis of rotation, and (2) a position of the impeller within the blood flow channel transverse to the impeller axis of rotation. A flow rate of blood pumped by the blood pump is estimated based on the impeller rotational speed and the at least one impeller transverse position parameter.
    Type: Application
    Filed: July 19, 2016
    Publication date: January 26, 2017
    Inventor: Christopher J. Cotter
  • Publication number: 20170021072
    Abstract: A blood clot removal device for removing blood clots from the vascular system of a patient is implantable in the patient's body. The blood clot removal device comprises a blood flow passageway to be connected to the patient's vascular system to allow circulation of the patient's blood through the blood flow passageway, a filter provided in the blood flow passageway for collecting blood clots occurring in the blood flowing through the blood flow passageway, and a cleaning device for moving blood clots collected by the filter out of the blood flow passageway. By means of such blood clot removal device, the risk of blood clots reaching sensitive areas of the patient's body, such as the brain, is reduced.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Inventor: Peter Forsell
  • Publication number: 20170021073
    Abstract: An implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle is provided. The device comprises at least one pump device having a pump. The pump comprising: a piston adapted for reciprocating movement, an operating device for operating the piston, a heart contacting organ. The movement of the piston assists the pump function of the heart through said heart contacting organ.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Inventor: Peter Forsell
  • Publication number: 20170021074
    Abstract: The invention relates to an implantable pump system for delivering blood within the body of a patient, with a blood pump which delivers a fluid in an axial direction and comprises a rotatingly drivable rotor as well as a pump casing surrounding the rotor, as well as a support tube, in which the pump casing is arranged and held, wherein an annular gap is formed between the support tube and the pump casing. An almost physiological blood flow is rendered possible in this manner, by way of the combination of a flow through the pump casing on the one hand, and the annular gap on the other hand.
    Type: Application
    Filed: July 20, 2016
    Publication date: January 26, 2017
    Inventors: Ulrich Tim Opfermann, Andreas Arndt, Volkmar Falk
  • Publication number: 20170021075
    Abstract: A hemodiafiltration system in accordance with an embodiment of the described system at least two dialyzers for hemodiafiltration, at least one dialysate supply, a sterility filter for generating a sterile substitution fluid, and a control unit which controls fluid (e.g., dialysate, substitution fluid, and blood) inputs and outputs to and from each of the at least two dialyzers, the at least one sterility filter, and the dialysis machine. The hemodiafiltration system described herein is capable of executing blood processing with enhanced clearance of small, middle, and large molecules using features that include independently supplying dialysate to multiple dialyzers.
    Type: Application
    Filed: July 21, 2015
    Publication date: January 26, 2017
    Inventors: Matthew Doyle, Eric Hoffstetter
  • Publication number: 20170021076
    Abstract: The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 26, 2017
    Applicant: Medtronic, Inc.
    Inventors: David B. LURA, Christopher M. HOBOT, Martin T. GERBER, Thomas E. MEYER
  • Publication number: 20170021077
    Abstract: Disclosed is a hollow molded article which has an opening portion communicating with a flow channel and which can be manufactured simply. The hollow molded article includes a panel and flow channels. The panel includes a first resin sheet and a second resin sheet partly welded with the first resin sheet. The flow channels are disposed between the first resin sheet and the second resin sheet, and include connection portions for external connection which are disposed on a peripheral edge of the panel. The connection portions are formed by the first resin sheet and the second resin sheet.
    Type: Application
    Filed: April 7, 2015
    Publication date: January 26, 2017
    Applicant: Kyoraku Co., Ltd.
    Inventors: Daisuke YAMAZAKI, Ryosuke OKI, Tomohiro TANIGUCHI
  • Publication number: 20170021078
    Abstract: The present invention relates to a combination of a container comprising a connecting portion and of a fluid preparation device, in particular a dialysis machine, which fluid preparation device is suitable for mounting and connecting the connecting portion of the container, wherein the fluid preparation device comprises at least one line which is in fluid communication with the interior of the container at least in the connected position of the container, the container being filled with a first medium, wherein the combination and preferably container comprises a reservoir containing a second medium, wherein the fluid preparation device comprises means for opening the reservoir so that the first and second medium are mixed with each other.
    Type: Application
    Filed: December 16, 2014
    Publication date: January 26, 2017
    Applicant: Fresenius Medical Care Deutschland GmbH
    Inventors: Winfried BREHM, Philippe LAFFAY, Benoit LUAIRE
  • Publication number: 20170021079
    Abstract: The invention relates to an infusate caddy for carrying, organizing, and operating infusate containers containing solutes for preparing dialysate and related fluids for use in dialysis. The infusate containers can be seated in the infusate caddy, and the infusate containers removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed, from the dialysis machine.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 26, 2017
    Applicant: Medtronic, Inc.
    Inventor: Medtronic, Inc.
  • Publication number: 20170021080
    Abstract: Extracorporeal life support (ECLS) systems, devices and methods wherein a portable ECLS device is used to deliver cardiovascular support to a humans or animal patient (or harvested organ(s)) during pre-hospital or inter-hospital transport.
    Type: Application
    Filed: July 23, 2015
    Publication date: January 26, 2017
    Inventors: Michael Bonczar, Thomas Bauer, Jeremy Thomas Dabrowiak, Werner Hestner
  • Publication number: 20170021081
    Abstract: A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.
    Type: Application
    Filed: January 28, 2016
    Publication date: January 26, 2017
    Inventors: Barry N. Gellman, Andrew Koert, Zhongjun Wu, Juntao Zhang, Bartley P. Griffith
  • Publication number: 20170021082
    Abstract: The present invention relates generally to a pulmonary assist device comprising a housing having tapered inlets and outlets to distribute blood evenly over a fiber bundle. The fiber bundle has a relatively low packing density to prevent the formation of clots. The invention is adapted to be used with a pump or without a pump, in which the heart supplies the necessary blood flow. Moreover, the device can be used as a single module or as multiple modules arranged in parallel.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Keith E. Cook, David Skoog
  • Publication number: 20170021083
    Abstract: A therapeutic apheresis system including a tube set and a panel is presented. The tube set includes an in-line pressure sensor in fluid connection with tubing. The panel includes apertures that are aligned with electrical connectors through which a rigid plug portion of an in-line pressure sensors extends and makes electrical connection with at least one electrical connector.
    Type: Application
    Filed: February 25, 2015
    Publication date: January 26, 2017
    Inventors: Paul Gray, Michael Collinson
  • Publication number: 20170021084
    Abstract: The invention relates to a medico-technical measuring device (1) for measuring a property of a fluid—in particular, for pressure measurement—comprising a line (20) extending along a central longitudinal axis (M) and configured to guide a fluid—in particular, blood—within a longitudinal cavity (24) delimited by a wall (22), and a sensor unit (30) having a sensor (32), which sensor unit is configured to measure a property of the fluid guided in the longitudinal cavity (24). The line (20) is provided with a radial cavity (26) inserted in the wall (22) in a radial direction, in which the sensor unit (30) is at least partially arranged, and which is integrated in the wall (22) such that the sensor (32) is in communication with the fluid. In this way, a measuring device can be provided that allows simple handling—in particular, in combination with a comparatively precise measurement—especially, pressure measurement.
    Type: Application
    Filed: May 15, 2015
    Publication date: January 26, 2017
    Inventors: Andreas Maurer, Sven Filipon, Matthias Beurer
  • Publication number: 20170021085
    Abstract: The application is directed to an extracorporeal blood processing system capable of using dialysate to prime the system. A plastic molded compact manifold supports molded blood and dialysate fluidic pathways along with relevant sensors, valves and pumps. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. A two-way valve in the manifold is used to direct the dialysate flow through the blood circuit to prime the circuit for use in treatment.
    Type: Application
    Filed: February 16, 2016
    Publication date: January 26, 2017
    Inventors: Barry Neil Fulkerson, Martin Hering, Frank Isackson
  • Publication number: 20170021086
    Abstract: The invention relates to devices, systems, and methods for priming, disinfecting, and preparing dialysate and related fluids for use in dialysis. The dialysate and related fluids can be prepared from solutes obtained from infusate containers seated in an infusate caddy. The infusate caddy can be removably positioned in a receiving compartment of a dialysis machine. Similarly, the infusate containers containing the necessary solutes for preparing the dialysate and related fluids can also be removably positioned in the infusate caddy.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 26, 2017
    Applicant: Medtronic, Inc.
    Inventors: David B. LURA, Christopher M. HOBOT, Martin T. GERBER, Thomas E. MEYER
  • Publication number: 20170021087
    Abstract: A medical blood access system used for hemodialysis treatment to enable blood withdrawal for processing of blood by an external apparatus and return the same blood to a patient, comprising an interfacial fluid conduit between the machine and patient's blood supply which is repeatedly connectable along a guided pathway passing through epidermis and subcutaneous tissue via a naturally formed tissue tract to enter blood space, providing improved patient safely, convenience, effective prophylaxis, without bleeding or tissue trauma or pain, and is executable by the patient to precisely connect and disconnect with minimal disfigurement or life restrictions, and is useable on virtually all patients soon after placement and is robust and safe to high blood flow.
    Type: Application
    Filed: February 25, 2016
    Publication date: January 26, 2017
    Inventors: Frank Prosl, Hans-Dietrich Polaschegg
  • Publication number: 20170021088
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The manifold includes diaphragms adapted to minimize the dead space between the dialysis machine pins and improve responsivity. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface and a heater in thermal communication with the container. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Application
    Filed: February 29, 2016
    Publication date: January 26, 2017
    Inventors: Barry Neil Fulkerson, Alec Huang, Brian Thomas Kelly
  • Publication number: 20170021089
    Abstract: A cannula ingress system may include a tip stabilization mechanism having a tip stabilization mechanism distal end and a tip stabilization mechanism proximal end, a fixation mechanism, a hypodermic tube having a hypodermic tube distal end and a hypodermic tube proximal end, and a tip having a tip distal end and a tip proximal end. The tip may be disposed within the hypodermic tube wherein the tip distal end extends from the hypodermic tube distal end. The fixation mechanism may be disposed within a fixation mechanism channel of the tip stabilization mechanism. The tip stabilization mechanism may be disposed over the tip and the hypodermic tube distal end.
    Type: Application
    Filed: August 6, 2015
    Publication date: January 26, 2017
    Inventors: Gregg D. Scheller, Steven G. Scheller, Bradley S. Niehoff
  • Publication number: 20170021090
    Abstract: A medical infusion device including a chamber characterized by an upper body joined to a lower body via a reversibly collapsible sidewall. The upper body has a first channel fluidly coupled to a needle and a second channel fluidly coupled to an interior of the chamber.
    Type: Application
    Filed: October 3, 2016
    Publication date: January 26, 2017
    Inventors: David Stroup, Arthur Deptala, Jonas Cochran
  • Publication number: 20170021091
    Abstract: Systems and devices for maintaining a consistent input fluid height as fluid is consumed during infusion pump testing including a first hook disposed on an end of a first balancer arm; a second hook disposed on an end of a second balancer arm; and an aperture disposed in a connecting member; where the aperture is configured to be a pivot point for the device; and where the device is rotatable between a deployed position and a stored position.
    Type: Application
    Filed: February 9, 2016
    Publication date: January 26, 2017
    Inventors: Gregory Randolph Alkire, Karl A. Ruiter
  • Publication number: 20170021092
    Abstract: The invention provides a medical intravenous support apparatus that facilitates patient mobility while reducing the likelihood of an accidental fall. The design incorporates improved features for bag support, tube management, cord management, patient steadiness, user-friendly braking, and electric power supply.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 26, 2017
    Inventor: Steven Mellard
  • Publication number: 20170021093
    Abstract: A medical device with a self-sustaining power source is disclosed herein. The medical device includes a pump and at least one mechanical activation mechanism for engaging the pump to cause a dose event. An energy generator coupled to the activation mechanism generates energy each time the activation mechanism is actuated. The generated energy is supplied to a dose counter of the infusion device.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 26, 2017
    Inventors: David ELDER, Malcolm D. HAMER
  • Publication number: 20170021094
    Abstract: An infusion pump system is disclosed. The system includes a syringe having a plunger within the syringe barrel, the syringe having an exit end, at least one temperature determination device adjacent to the syringe, at least one device to determine the distance the plunger has moved with respect to the syringe barrel, and a pump processor in communication with the at least one temperature determination device and the at least one optical sensor, wherein when the controller determines a change in temperature and a corresponding plunger movement, the controller increases or decreases a preprogrammed basal rate of the infusion pump by a predetermined amount for a predetermined time.
    Type: Application
    Filed: October 3, 2016
    Publication date: January 26, 2017
    Inventors: Dean Kamen, John M. Kerwin, Gregory R. Lanier, Larry B. Gray
  • Publication number: 20170021095
    Abstract: A medical infusion system including an illuminating infusion line, wherein the illuminating infusion line has at least one inline component, the inline component causing an interruption in a light transmission channel of the illuminating infusion line; and a first and second source of illumination residing on either side of the inline component.
    Type: Application
    Filed: March 11, 2016
    Publication date: January 26, 2017
    Inventor: Hans Utz
  • Publication number: 20170021096
    Abstract: An insulin infusion device (1A) is disclosed. The device includes a body (3A), cannula (70) housed in the body (1A), a cannula insertion device (10, 20, 23) and a cannula retraction device (20, 23, 30). When the cannula insertion device is activated, the cannula (70) extends at least partly out of the body (1A) and into an infusion site and when the cannula retraction device is activated after the cannula insertion device has been activated, the cannula (70) retracts into the body (1A).
    Type: Application
    Filed: April 23, 2015
    Publication date: January 26, 2017
    Applicant: Becton, Dickinson and Company
    Inventors: Russell Cole, Michael Creighton, Shuichi Amano, Gary Reuther, Arthur Klotz, Alyssa Jackson
  • Publication number: 20170021097
    Abstract: A medical device, such as a Huber-type device, includes a structure that enhances operator safety by reducing the likelihood that a needle will accidentally injure an operator. In one embodiment, the device includes a collapsible structure that can move from a use position to a non-use position. The device includes first and second wing portions and a channel for covering the needle as it is extracted from the patient. The structure enables the operator to leverage applied pressure for a smooth removal of the needle into the device for safe disposal.
    Type: Application
    Filed: October 5, 2016
    Publication date: January 26, 2017
    Inventor: Alan Reid
  • Publication number: 20170021098
    Abstract: Systems and methods for automatic flow termination for fluid delivery, including a housing configured for coupling a fluid delivery tube to a needle configured for subcutaneous delivery of fluid within a tissue of a patient and a spring-loaded activation mechanism having a first orientation corresponding to a condition where the housing is disposed substantially adjacent to the tissue and the needle lodged within the tissue and a second orientation corresponding to a condition where the housing is disposed away from the tissue or the needle being dislodged from the tissue. A flow termination mechanism is coupled to the activation mechanism and having an open configuration allowing flow from the fluid delivery tube to the needle when the activation mechanism is in the first orientation and a closed configuration substantially terminating flow from the fluid delivery tube to the needle when the activation mechanism is in the second orientation.
    Type: Application
    Filed: October 5, 2016
    Publication date: January 26, 2017
    Applicant: Hemotek Medical Incorporated
    Inventors: Patrick ROUSCHE, Peter TEK, Charles VENTURA, Richard A. SCRIBNER
  • Publication number: 20170021099
    Abstract: The present disclosure describes embodiments of a patient monitoring system and methods that include the measure and display of hemoglobin statistics. In an embodiment, total hemoglobin trending is displayed over a period of time. Statistics can include frequency domain analysis, which may be unique for each patient monitored. The total hemoglobin trending and/or statistics can further be used to help control the treatment of a patient, such as being used to control IV administration.
    Type: Application
    Filed: June 16, 2016
    Publication date: January 26, 2017
    Inventors: Ammar Al-Ali, Massi Joe E. Kiani, Michael O'Reilly
  • Publication number: 20170021100
    Abstract: A system and method for providing closed loop infusion formulation delivery which accurately calculates a delivery amount based on a sensed biological state by adjusting an algorithm's programmable control parameters. The algorithm calculates a delivery amount having proportional, derivative, and basal rate components. The control parameters may be adjusted in real time to compensate for changes in a sensed biological state that may result from daily events. Safety limits on the delivery amount may be included in the algorithm. The algorithm may be executed by a computing element within a process controller for controlling closed loop infusion formulation delivery. The biological state is sensed by a sensing device which provides a signal to the controller. The controller calculates an infusion formulation delivery amount based on the signal and sends commands to an infusion formulation delivery device which delivers an amount of infusion formulation determined by the commands.
    Type: Application
    Filed: September 30, 2016
    Publication date: January 26, 2017
    Inventors: Timothy J. Starkweather, Ronald J. Lebel, Rajiv Shah, Michael E. Miller
  • Publication number: 20170021101
    Abstract: Some embodiments of a wearable infusion pump system can include a pump device having a drive system to dispense a medicine to a user, an activity sensor that detects a possible change in an activity level of the user, and a controller to activate the drive system to dispense the medicine to the user. The controller device can query the user to indicate whether a detected activity level of the user represents an actual change in the activity level of the user. The controller device can alter the medicine dispensing schedule based on the user indicated changes in activity level.
    Type: Application
    Filed: October 5, 2016
    Publication date: January 26, 2017
    Inventors: Mark C. Estes, Deb Ruppert
  • Publication number: 20170021102
    Abstract: A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Inventor: Oscar Alexandersson
  • Publication number: 20170021103
    Abstract: An autoinjector includes a case adapted to hold a medicament container having a needle telescopically coupled to the case and movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The autoinjector includes a plunger rotationally and slidably disposed in the case rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case engages the plunger to rotate the plunger from the first rotational position to the second rotational position when the needle shroud translates from the first extended position to the retracted position. The autoinjector includes a cap removably coupled to the case includes at least one compliant case beam adapted to releasably engage at least one aperture in the case.
    Type: Application
    Filed: March 27, 2015
    Publication date: January 26, 2017
    Inventors: Carsten Mosebach, Thomas Kemp
  • Publication number: 20170021104
    Abstract: A medication administration device is provided. The device has a flexible tube having an administration end, an activation end and a lumen between the ends. An administration assembly is attached to the administration end. An activation assembly is attached to the activation end. A syringe is disposed within the lumen. The syringe contains the medication and has a first end and an opposite second end. A plunger is disposed within the lumen and operatively connected to the first end of the syringe. A rupturable seal is provided to the second end of the syringe, which end is approximate to the administration end. The activation assembly activates the plunger to break the rupturable seal to establish a fluid communication between the second end of the syringe and the administration assembly. Accordingly, transportation of the medication from the syringe to the medication administration assembly through the medication administration end is allowed.
    Type: Application
    Filed: October 1, 2016
    Publication date: January 26, 2017
    Inventor: Jessica Walsh
  • Publication number: 20170021105
    Abstract: A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Inventor: Oscar Alexandersson