Abstract: Disclosed herein is a system and method for characterizing adventitial tissue. In one aspect, a system and method is disclosed that characterizes tissue types within the adventitial tissue including nerve bundles and blood vessels. In a further aspect, the adventitia is imaged and characterized to provide guidance for crossing lesions within an occluded vessel.

Abstract: An ultrasonic diagnostic apparatus disclosed herein comprises an ultrasonic probe which generates an ultrasonic beam, a volume data set collecting unit which collects a plurality of volume data sets corresponding to a plurality of three-dimensional scan ranges via the ultrasonic probe, the plurality of three-dimensional scan ranges partly overlapping one another, a region of interest setting unit which sets, in accordance with a user instruction, a region of interest on a first tomogram generated from particular one of the plurality of volume data sets, a tomogram generating unit which generates the first tomogram from the particular volume data set and also generates a second tomogram associated with a section including the region of interest from another volume data set corresponding to the three-dimensional scan range including the region of interest, and a display unit which displays the first tomogram and the second tomogram.

Abstract: A monitoring device (1) is provided for monitoring the presence of a skin piercing vascular access device, for example a needle (4), the monitoring device comprising: a mount having an ultrasonic transmitter and an ultrasonic receiver therein; attachment means (3) for attaching the mount to a patient adjacent a vascular access point such that, in use, a vascular access device (4) entering the patient at the vascular access point, passes underneath a sensing section of the base; control electronics to monitor the signal received at the receiver, and wherein when the vascular access device is underneath said sensing section, ultrasound produced by said transmitter passes through the patient skin and is reflected by the patients body tissues and by the vascular access device (4), and when the vascular access device (4) is not underneath said sensing section, ultrasound produced by said transmitter passes through the patients skin and is reflected by the patients body tissue only, and wherein the control electron

Abstract: Ultrasound devices and methods are described, including a repeatable ultrasound transducer probe having ultrasonic transducers and corresponding circuitry. The repeatable ultrasound transducer probe may be used individually or coupled with other instances of the repeatable ultrasound transducer probe to create a desired ultrasound device. The ultrasound devices may optionally be connected to various types of external devices to provide additional processing and image rendering functionality.

Abstract: An ultrasonic transducer device includes a base, a first electrode film, a piezoelectric film, a second electrode film and a first conductive film. The base has a plurality of vibrating film portions arranged in an array pattern. The first electrode film is disposed on each of the vibrating film portions. The piezoelectric film is disposed on the first electrode film. The second electrode film is disposed on the piezoelectric film. The first conductive film is connected to the first electrode film. The first conductive film has a film thickness larger than a film thickness of the first electrode film.

Abstract: To implement a single-chip ultrasonic imaging solution, on-chip signal processing may be employed in the receive signal path to reduce data bandwidth and an output data module may be used to move data for all received channels off-chip as a digital data stream. The digitization of received signals on-chip allows advanced digital signal processing to be performed on-chip, and thus permits the full integration of an entire ultrasonic imaging system on a single semiconductor substrate. The on-chip digitization of received signals also enables the on-chip integration of ultrasound processing and/or pre-processing to reduce the burden on off-chip computing. Data compression architectures are disclosed to facilitate the transfer of data off-chip as a digital data stream in accordance with the bandwidth requirements of standard commercially-available output interfaces.

Abstract: An information processing apparatus according to the present invention causes an alarm output means to output an alarm at a preset time, causes the alarm output means to stop outputting the alarm when a stop instruction is input by a user while the alarm is being output, and makes a transition to a standby state in which biological information wirelessly transmitted from a measurement instrument can be received in response to the stop of the alarm.

Abstract: The present invention relates to a urine specimen capture device comprising a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl.

Abstract: An excisional device for either handheld car stereotactic table use may comprise an outer sheath that may comprise a distal scoopula shape configured to penetrate and/or cut tissue independently or in concert with work element(s). The articulable work element(s) may comprise articulable beak(s) and may be configured to translate and/or rotate at a first rate and to cut tissue in a direction implied by placement of the scoopula shaped outer sheath. A first helical element or equivalent assembly may be configured to transport tissue cut by the work element(s) and/or scoopula, may be co-axially disposed relative to the work element(s) and may be operative to rotate at a second rotation rate that is different than the first rate. A proximal sheath may be co-axially disposed relative to the work element(s) and the first helical element, and may be configured to rotate and actuate the work element(s).

Abstract: A multi-functional medical device including a sheath having a proximal end, a distal end, and a lumen extending between the proximal end and the distal end. The medical device further includes an end-effector slidably disposed within the lumen. A portion of the end-effector may be configured to transition between a collapsed state while in the lumen and an expanded state while out of the lumen. Further, the end-effector may include a tool configured to dissect tissue, and a retracting member having a plurality of legs disposed about the tool.

Abstract: Methods, devices and systems are described for treating venous insufficiency in which the vein is compressed at least partially along a treatment zone. A system can be provided including an injection device, such as a glue gun, that is operably connected to a delivery catheter that can be advanced across a treatment zone in the vein. The delivery catheter can be used to deliver one, two, or more boluses of media (e.g., cyanoacrylate) to occlude the vein along different spaced-apart sections of the treatment zone. External compression can also be applied to the vein by a compression element, such as a hand or multifunctional ultrasound transducer, to occlude portions of the vein along the treatment zone prior to or during the introduction of the boluses of media.

Abstract: A surgical device of suturing vascular vessels is described, as well as methods for suturing tissue employing the surgical device. In one form the device includes a distal member that contains a suture and needle engaging fitting. A needle is advanced through tissue adjacent the puncture wound and into the needle engaging fitting to draw lengths of suture material which can then be used to close the puncture wound. In another form the device includes a needle advanceable through tissue and into a needle capture element within a distal end of the surgical device to draw lengths of suture material which can then be used to close various puncture wounds. In still another form the device includes at least one needle advanceable to draw lengths of suture material to close various puncture wounds. A foot is pivotal between a non-deployed and a deployed position.

Abstract: A tissue puncture locator device includes an anchor assembly and a sealing member. The anchor assembly includes an anchor portion, a tube portion, and a filling member. The anchor portion is positioned at a distal end of the tube portion and configured for placement through a vascular incision into a vessel. The anchor member has an unexpanded configuration that permits passage through the vascular incision and an expanded configuration that limits passage through the vascular incision. The filling member is retained in the tube portion and adapted for insertion from the tube portion into the anchor member to provide the expanded configuration, and adapted for retraction from the anchor member into the tube portion to provide the unexpanded configuration. The sealing member is configured for placement adjacent the vascular incision outside the vessel.

Abstract: An array of a plurality of shape memory material microposts have a proximal end configured to be secured to a substrate with a tissue penetrating distal end. The microposts further have a deployment state with the microposts in a substantially straightened configuration with a substantially smooth and continuous outer surface which is substantially parallel to adjacent microposts and an engaged state wherein at least a section of the microposts assume a configuration that is not substantially parallel to adjacent microposts or is not substantially straight with a substantially smooth and continuous outer surface so as to mechanically capture tissue adjacent thereto.

Abstract: A surgical retractor comprises a support comprising a first mating part comprising a shaft, which defines a longitudinal axis, extending therefrom. At least one tissue engaging member extends between a first end defining a first axis and a second end defining a second axis and having a tissue engaging surface disposed along the second axis. The first end comprises a second mating part comprising a wall that defines an elongated cavity disposed along the first axis and being configured to receive the shaft such that the first axis and the longitudinal axis are co-axial. The wall is engageable with the shaft to align the second mating part with the first mating part such that the second axis intersects the longitudinal axis. Methods of use are disclosed.

Abstract: The present invention relates to a device for creating a working space within a human or animal body. The device comprises an outer wall which is configurable to adopt a non-expanded condition and an expanded condition. When the outer wall is in said expanded condition it defines a hollow body having an inner cavity in communication with an orifice for location adjacent a working site within the body such that, in use, said working site can be visualized and/or accessed via said inner cavity and said orifice.

Abstract: Medical devices having more than one degradation zone or degradation mechanism are used for orthopedic repair devices and soft tissue fixation devices.

Abstract: A delivery device for inserting a plurality of T-fastener-equipped sutures into a body of a patient in a spaced-apart configuration for the purpose of securing the stomach wall against the abdominal wall, also known as gastropexy, is disclosed. The suture delivery device is configured to deliver multiple sutures using a single needle and without need for reloading, saving time and effort for the clinician and simplifying the suture placement process. In one embodiment, a T-fastener-equipped suture delivery device comprises a housing, a hollow needle extending from the housing, and a plurality of T-fastener-equipped sutures at least partially disposed within one of the needle and the housing. An ejection assembly for successively ejecting the T-fasteners from a distal end of the needle without reloading the delivery device is also included in the housing.

Abstract: In accordance with the present invention there is provided apparatuses and methods for using a medical instrument including a sizing and positioning adapter. The apparatus comprises an adapter for a medical instrument, the adapt having a body having a shim portion and an instrument holding portion adjacent the shim portion, wherein the shim portion provides an enlarged peripheral surface adjacent the medical instrument such that when the medical instrument is held in the instrument holding portion and the medical instrument and body are inserted through an opening in a patient tissue, at least a portion of the enlarged peripheral surface is in contact with at least a portion of the periphery of the opening in the patient tissue.

Abstract: A system and method are disclosed for the securement of tissue and in particular for placement of a tongue base suspension fiber for the treatment of obstructive sleep apnea. The system incorporates disposable connectors with releasable needles to facilitate the placement of fibers with minimal increase in suture site dilation or trauma.

Abstract: Described herein are systems and methods for securing sutures that obviate the need for tying knots. Instead of tying two ends of a suture or two sutures together with a knot, two or more suture portions can be fused or cauterized together using heat. A device can be applied to adjacent suture portions that heats the suture portions and causes the suture portions to fuse together, effectively securing the suture portions together without a knot.

Abstract: A knotless suture fastener installation system for securing medical devices such as cardiac implants. The knotless suture fasteners may be spring-biased so as to grip onto sutures passed therethrough. The system includes a fastener deployment tool with a proximal handle and a distal shaft to which a fastener cartridge attaches. A plurality of disposable cartridges are sequentially attached to the end of the deployment tool and used to secure the medical implant one fastener at a time. The deployment tool may also cut the sutures being fastened.

Abstract: A mechanical system for rotatably, sequentially securing opposing sides of a tissue wound with a fastener. An applicator apparatus is capable of imparting rotatable motion to a falcate tissue penetrator that sequentially pierces and carries a fastener into a first side and a second side of the tissue wound. The first side and second side of tissue can be simultaneously captured and positioned with respect to a tissue definition member or alternatively, the first tissue side and second tissue side can be individually, sequentially captured and positioned relative to the tissue definition member. The applicator apparatus can comprise a single fastener for small tissue wounds or resections or alternatively, the applicator can comprise a plurality of staged fasteners for use in closing a larger wounds or wounds with increased tension.

Abstract: A fastener cartridge can comprise a cartridge body comprising fastener cavities, fasteners at least partially stored within the cartridge body, and a layer positioned over the cartridge body. The cartridge body can include a proximal end and a distal end. Similarly, the layer can include a proximal end and a distal end. The distal end of the layer can extend distally with respect to the distal end of the cartridge body. Furthermore, the layer can include a distal portion which extends distally with respect to the fastener cavities defined in the cartridge body. This distal portion can be positioned against the tissue being fastened and can flexibly support the tissue after the layer has been implanted against the tissue. The layer may include a proximal portion which extends proximally with respect to the fastener cavities which can flexibly support the tissue after the layer has been implanted.

Abstract: A surgical stapling instrument comprising a handle assembly having a proximal end, an elongated body portion extending distally from the handle assembly, a head portion disposed adjacent a distal portion of the elongated body portion and including an anvil assembly and a shell assembly. The shell assembly includes a shell and a staple guide housing a plurality of staples. A flexible engagement structure attaches the staple guide to the shell.

Abstract: A surgical stapling assembly can include a staple cartridge, an anvil, and a firing system configured to eject staples from the staple cartridge. The firing system can include a firing member configured to relatively position the anvil and the staple cartridge. The staple cartridge can include a first deck portion, a second deco portion, and a wall defined between the first deck portion and the second deck portion.

Abstract: A staple cartridge includes a plurality of staples, wherein each said staple comprises a base and a deformable leg extending from said base. The staple cartridge further includes a first region comprising a first density, a second region, and a third region comprising a density greater than said first density, wherein said third region is separable into a plurality of pieces.

Abstract: A staple cartridge for use with a surgical stapler can comprise a cartridge deck and a plurality of staples at least partially positioned within the cartridge deck. In various embodiments, the staples can be supported by a support jaw of the surgical stapler and can comprise legs which can extend upwardly through apertures defined in the cartridge deck. In use, the cartridge deck can be pushed downwardly relative to the staples into a well defined in the support jaw.

Abstract: A surgical stapling device is disclosed for the treatment of internal hemorrhoids. The surgical stapling device includes a handle portion, an elongated body portion and a head portion including an anvil assembly and a shell assembly. The head portion includes an anvil assembly including a tiltable anvil which will tilt automatically after the device has been fired and unapproximated. The tiltable anvil provides a reduced anvil profile to reduce trauma during removal of the device after the anastomoses procedure has been performed. The anvil assembly of the stapling device may include an approximation mechanism having an anvil retainer including an elongated distal extension dimensioned to be telescopingly received within a longitudinal bore of an anvil center rod of the anvil assembly. The elongated distal extension is of a length to provide telescopic engagement with the anvil center rod without obstructing visualization of the surgical site.

Abstract: A stapler is provided. The stapler includes a handle assembly and a shaft extending distally from the handle assembly. A tool assembly is configured to selectively couple to the shaft and includes a cartridge assembly and an anvil assembly. The cartridge assembly includes a staple guide defining a tissue contacting surface. A resilient member operably positioned within the cartridge assembly is configured to bias the staple guide distally to provide a predetermined compressive force against tissue when the cartridge assembly and anvil are approximated toward one another.

Abstract: A lung volume reduction system includes a percutaneously, laparoscopically or thorocospically insertable delivery element comprising a control end which remains outside the body and an insertion end which, when in an operative position, is adjacent to an external surface of a target portion of a lung and a constriction element deployable from the distal end of the delivery element to apply compressive force to an external surface of the target portion of the lung to constrict at least one airway therein and collapse the target portion of the lung.

Abstract: A medical device implant for the left atrial appendage of a patient's heart, to prevent strokes. The device includes a cap that overlies the opening of the LAA connected to a bulb in the LAA. Dis-continuous segmented sails attached to the cap promote tissue growth over the device.

Abstract: The present invention relates generally to an emergency tourniquet for rapidly and easily reducing or stopping blood flow to an injured limb. The tourniquet utilizes a closed loop system that is formed by passing a portion of a twistable strap, which comprises the loop, through a side opening in a buckle and cinching the strap tightly above an injury and thereafter twisting the strap. Otherwise, a loop may be formed and the injured limb passed through the loop prior to tightening it about the injured limb. The buckle includes an elongated opening that accepts an end or edge of the twistable strap. A free end of the twistable strap passes into a J-hook opening and is secured therein. The strap is then twisted and a notch in the buckle is hooked on an edge of the twistable strap. Bulbous regions are provided on either end of the buckle. A base plate may also be included for further securing the buckle in place to maintain the tourniquet in place until it can be removed by a competent medical professional.

Abstract: Disclosed are methods and devices for obtaining patent hemostasis of the radial artery by compressing the uninstrumented ulnar artery to increase radial artery flow. The device comprises a band having an inflatable bladder for applying blunt pressure to the ulnar artery. The method comprises applying a pressure to the homolateral ulnar artery and applying a pressure to the radial artery at the access site to obtain hemostasis at the access site.

Abstract: A reamer assembly, comprising a modular drill tip having a cutting edge proximate a first end, a pair of flexible arms extending from and proximate to a second end and a first through-hole positioned between the first and second ends along a longitudinal axis, wherein the first through-hole is configured to receive a guide wire during a reaming process; and a reamer shaft having a receiving end that is configured to receive and releasably hold in axial alignment thereto the pair of flexible arms, the reamer shaft having a second through-hole that is configured to receive the guide wire during the reaming process, wherein the first and second through-holes together create a common through-hole that is positioned along the longitudinal axis.

Abstract: Methods and apparatus for treating disc herniation provide a conformable device which assumes a first shape associated with insertion and a second shape or expanded shape to occlude the defect which typically follows partial discectomy. The device may take different forms according to the invention, including patches size to cover the defect or plugs adapted to fill the defect. In a preferred embodiment, however, the device is a gel or other liquid or semi-liquid which solidifies to occlude the defect from within the body of the disc itself. In another preferred embodiment, a mesh screen is collapsed into an elongated form for the purposes of insertion, thereby minimizing the size of the requisite incision while avoiding delicate surrounding nerves.

Abstract: A method of trialing an intervertebral disc space, including the steps of creating the disc space, inserting a trial into the disc space, wherein the trial has i) a distal head having an upper surface and a lower surface connected by a pair of side walls, the side walls defining planes, and ii) a proximal rod, so that the head and rod form an obtuse angle and the rod extends through at least one of the planes defined by the side walls of the head.

Abstract: A targeting device for guiding a drill arrangement for forming an arc-shaped bore in an assembly of adjacent bones or bone fragments, comprises a support frame, a pivoting device mounted to the support frame and arranged to receive the drill arrangement and to allow a pivoting movement of the drill arrangement along an arc-shaped path having a predetermined radius of curvature rc around a pivot axis. The support frame is provided with at least three fixation devices each configured to fix a bone or bone fragment of the bone assembly to define a fixed position in space of the bone assembly with respect to the pivoting device when the bone assembly is installed on the support frame.

Abstract: A surgical device for guiding a key wire during a shoulder arthroplasty procedure, including a guide for guiding a key wire during the process of drilling into a scapula, and a clamp configured to engage with the scapula neck such that a key wire located in the guide is located in a predetermined geometrical relationship with the scapula neck.

Abstract: A hand-held gripping device that allows one of a surgeon, a dentist, and an orthodontist to reach interior portions of a person's anatomy, includes a gripping portion having a pair of jaws movable relative to each other between fully clamped and fully opened positions thereof, a handle portion spaced apart from the jaw portion by a bendable central portion that has a hollow, bendable corrugated with at least one cord extending therethrough.

Abstract: A specimen retrieval device is provided. The specimen retrieval device includes a housing that includes an outer shaft extending distally therefrom. An inner shaft is disposed within the outer shaft and includes a spring including two or more members. One or both of the members includes a support member interface member. A pouch is releasably couplable to the members and includes a cinch having a proximal end that is passable through the outer shaft for grasping by a user. The pouch includes a pair of openings that lead to a sleeve that is provided on the pouch. Each of the openings is configured to receive a respective one of the members so as to allow the support member interface member on the member(s) to engage a corresponding pocket on the pouch.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: An instrument for differentially dissecting complex tissue is disclosed, comprising a handle, a central longitudinal axis, and an elongate member, with a differential dissecting member (DDM) configured to be rotatably attached to a distal end. The DDM comprises at least one tissue engaging surface, a first torque-point disposed to a first side of an axis of rotation, and a mechanism configured to rotate the DDM around the axis of rotation, causing the tissue engaging surface to move in at least one direction against the complex tissue. The mechanism comprises at least one force-transmitting member attached to the first torque-point member and to a motive source configured to oscillate the DDM. The tissue engaging surface is configured to selectively engage the complex tissue such that it disrupts at least one soft tissue in the complex tissue, but does not disrupt firm tissue in the complex tissue.

Abstract: There is provided a method of treating gastroesophageal reflux disease, which includes dissecting one of a mucosal layer and a submucosal layer of at least one of an esophagogastric junction and a stomach in a range less than an entire circumference of a circumferential direction so that moderate stenosis occurs due to cicatrization in an area in which one of the mucosal layer and the submucosal layer is dissected.

Abstract: A surgical grooved director including a fixed or removable handle with a tubular member having a lumen extending therethrough with an aperture at its proximal end and a blunt dissecting distal tip. An access window is formed through the wall of the tubular member in a distal portion of the instrument and is in communication with the lumen. An integral side rail is integrally mounted on the tubular member and defines a linear groove adapted to receive and allow slideable movement of a knife.

Abstract: In an ultrasonic probe, an insulation layer portion is formed on an outer surface of a probe main body portion. A first electrode portion provided on an outer surface of the insulation layer portion so that at least part of the first electrode portion is exposed to an outside in a treatment section, and at least part of a second electrode portion is exposed to the outside in the treatment section. The second electrode portion is electrically insulated from the first electrode portion by the insulation layer portion. The probe main body portion vibrates integrally with the insulation layer portion, the first electrode portion and the second electrode portion.

Abstract: A fluid ejection device includes: a fluid chamber; a volume varying unit configured to vary the volume of the fluid chamber; a fluid supplying unit configured to supply fluid to the fluid chamber at a predetermined pressure; and an ejection command switching unit configured to switch a fluid ejection between a pulsed flow ejection which ejects the fluid in a pulsed manner by activating the volume varying unit and varying the volume of the fluid chamber and a continuous flow ejection which ejects the fluid with a fluid supply pressure from the fluid supplying unit higher than that in the case of the pulsed flow ejection in a state in which the volume varying unit is stopped.

Abstract: A microsurgical instrument has a pair of operative surgical surfaces that are moved relative to each other in shearing or grasping procedures performed by the instrument. The instrument has a handle containing an elongate center rod with a ring mounted for reciprocating movement on the rod. A tube is secured to the ring and a shaft extends through the tube and is secured to the rod. The handle also includes a plurality of resilient arms that extend along the length of the rod and engage against a sliding surface of the ring on the rod. The plurality of actuator arms are alternatively manually compressed radially inwardly by the surgeon's hand and released by the surgeon's hand to allow the arms to flex radially inwardly and outwardly. The inward and outward movement of the plurality of arms reciprocates the ring on the handle rod and causes the tube and shaft to move axially relative to each other.

Abstract: Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.

Abstract: A head assembly (200) for a power operated dermatome (100) including a frame body or housing (202) supporting a gear train (520), a blade housing assembly (400), an annular rotary knife blade (300) supported for rotation about an axis of rotation (R) by the blade housing assembly (400). The rotary knife blade (300) includes an inner wall (365) defining an interior region (301) and has a cutting edge (360) at one end (368) defining a cutting plane (CP). The head assembly (200) further includes a depth gauge assembly (600) including a depth gauge support (602) and a depth gauge (620) including a depth gauge plate (622) supported by the depth gauge support (602) for axial movement along the axis of rotation (R), the depth gauge plate (622) extending into the interior region (301) and the depth gauge support (602) attached to and extending from the frame body (202).