Patents Issued in August 1, 2017
  • Patent number: 9717818
    Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at one least substance including dimethicone and/or at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: August 1, 2017
    Assignee: Medline Industries, Inc.
    Inventors: Min Yao, Daniel B. Love, Amin Setoodeh, Debashish Chakravarthy
  • Patent number: 9717819
    Abstract: The present invention relates to a polyurea system, the use of such a polyurea system for sealing, linking, gluing, or covering of cellular tissue, and a dosing system having two chambers for a polyurea system such as this. The polyurea system comprises as components: A) an isocyanate-functioning prepolymer, which can be derived by reacting aliphatic isocyanates with polyoles, and B) an amino-functioning ester of aspartic acid. According to the invention, water and/or tertiary amine is added to the system, in order to increase the reacting speed of the prepolymer with the amino-functioning ester of aspartic acid while decreasing the setting time at the same time.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: August 1, 2017
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Hartmut Nefzger, Christoph Eggert
  • Patent number: 9717820
    Abstract: The present invention is directed to a hemostatic or tissue sealing material having (a) a peptide having a sequence SEQ ID NO: 1 or an amino acid analog sequence thereof, and (b) a scaffold for said peptide or amino acid analogue sequence. The scaffold is preferably hemostatic, such as a natural or genetically engineered absorbable polymer, a synthetic absorbable polymer, or combinations thereof. The natural or genetically engineered absorbable polymers can be selected from the group consisting of a protein, a polysaccharide, or combinations thereof.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: August 1, 2017
    Assignee: Ethicon, Inc.
    Inventors: Yi-Lan Wang, Guanghui Zhang
  • Patent number: 9717821
    Abstract: The present invention relates to novel formulations comprising a dry powder fibrin sealant comprised of a mixture of fibrinogen and/or thrombin, for use in the treatment of wounds or injuries, in particular for use as a topical hemostatic composition or for surgical intervention.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: August 1, 2017
    Assignee: Mallinckrodt Pharma IP Trading D.A.C.
    Inventors: Eliane Schutte, Linda Zuckerman, Richard Senderoff, Glen Martyn
  • Patent number: 9717822
    Abstract: Osteoinductive compositions and implants having increased biological activities, and methods for their production, are provided. The biological activities that may be increased include, but are not limited to, bone forming; bone healing; osteoinductive activity, osteogenic activity, chondrogenic activity, wound healing activity, neurogenic activity, contraction-inducing activity, mitosis-inducing activity, differentiation-inducing activity, chemotactic activity, angiogenic or vasculogenic activity, and exocytosis or endocytosis-inducing activity. In one embodiment, a method for producing an osteoinductive composition comprises providing partially demineralized bone, treating the partially demineralized bone to disrupt the collagen structure of the bone. In another embodiment, an implantable osteoinductive and osteoconductive composition comprises partially demineralized bone, wherein the collagen structure of the bone has been disrupted, and, optionally, a tissue-derived extract.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: August 1, 2017
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Keyvan Behnam, Guobao Wei, Nanette Forsyth
  • Patent number: 9717823
    Abstract: Compositions and methods for augmenting bone formation by administering isolated human mesenchymal stem cells (hMSCs) within a matrix provided. By adding calcium and/or phosphate ions to the matrix, one may foster greater bone regeneration.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: August 1, 2017
    Assignee: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Patent number: 9717824
    Abstract: A process for producing medical devices with functional surfaces, e.g., ceramic implants having bone-affine surfaces, and to medical devices produced in such a manner.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: August 1, 2017
    Assignee: CeramTec GmbH
    Inventor: Meinhard Kuntz
  • Patent number: 9717825
    Abstract: The present invention relates to a resorbable polymeric mesh implant, that is intended to be used in the reconstruction of soft tissue defects. The mesh implant has at least a first and a second material, wherein the second material is substantially degraded at a later point in time than the first material following the time of implantation. The mesh implant is adapted to have a predetermined modulus of elasticity that gradually is decreased until the mesh implant is completely degraded and subsequently resorbed. Due to the gradual decrease in the modulus of elasticity of the inventive mesh implant, the regenerating tissue may gradually take over the load applied to the tissue defect area. Interstices between individual filaments of multifilaments create a capillary effect for cells within the body.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: August 1, 2017
    Assignee: NOVUS SCIENTIFIC AB
    Inventors: Torbjörn Mathisen, Henrik Magnusson
  • Patent number: 9717826
    Abstract: A medical assembly is disclosed comprises a stent and a catheter having a balloon, wherein the coefficient of friction and/or the adhesion at the stent/balloon interface are reduced.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: August 1, 2017
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Stephen R. Dugan, Jessica R. Desnoyer, Stephen D. Pacetti, Bozena Maslanka
  • Patent number: 9717827
    Abstract: The present invention relates to biomaterials that interact with and regulate immune functions, as well as implantable materials and devices. In one embodiment, the present invention provides an implantable medical device comprising a biomaterial coated with one or more CD200 molecules. In another embodiment, the present invention provides a method of treating inflammation by administering a composition comprising one or more biomaterials that inhibit immune reactivity.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: August 1, 2017
    Assignee: The Regents of the University of California
    Inventors: Wendy Liu, Yoon Kyung Kim
  • Patent number: 9717828
    Abstract: The invention provides a vacuum tube attachment device for vacuum assisted wound dressings. The device is in the form of a patch that can be attached to the primary wound cover. The patch forms a substantially air-tight seal to the primary wound cover, and a vacuum tube is fixed to the patch such that the patch can be oriented on the wound cover to locate the tube near an opening in the cover to allow vacuum pressure to be communicated to the wound. The patch has an adhesive area around its perimeter for attaching the patch in a substantially air-tight seal to the wound cover at any convenient location on the cover. Several embodiments of the patch are described.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: August 1, 2017
    Assignee: Paul Hartmann AG
    Inventors: John Karpowicz, Christopher L. Radl, Kevin P. Klocek, John R. Boehringer
  • Patent number: 9717829
    Abstract: The present invention provides a device for wound treatment, comprising a chamber that includes an inner surface and defines a treatment space, the chamber being made of a flexible, impermeable material. The device further includes a plurality of structures configured to exert mechanical stress on a wound, the plurality of structures intruding from the inner surface of the chamber into the treatment space. The device further includes a tube having a first end connected to the chamber, the tube being in fluid communication with the treatment space so as to enable at least one selected from the group of applying negative pressure to the treatment space and applying a therapeutic agent.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: August 1, 2017
    Assignee: APPLIED TISSUE TECHNOLOGIES LLC
    Inventors: Elof Eriksson, W. Robert Allison, Christian Baker
  • Patent number: 9717830
    Abstract: A system and method of drawing blood from the heart of a patient. The system includes a blood pump, an outflow cannula, and a flexible cannula assembly. The flexible cannula assembly includes a cannula body, a tip, and first and second anchors. The cannula body includes a proximal end coupled to the inlet of the blood pump, a distal end including a first locking element coupled to the tip. The first anchor has a first plurality of arms and is coupled to the tip and adapted to engage the internal surface of the heart wall. The second anchor includes a second plurality of arms and a second locking element and is slidably positioned on the outer wall of the cannula body and adapted to engage the first locking element of the distal end of the cannula body to couple the second anchor to the external surface of the heart wall.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: August 1, 2017
    Assignee: CircuLite, Inc.
    Inventor: Robert C. Farnan
  • Patent number: 9717831
    Abstract: In one embodiment, the present invention is a method of positioning in a mammalian heart of a patient a blood pump including an inflow cannula, a pump housing and an outflow cannula, the method including forming an incision in a low-pressure location on the heart wall; passing the outflow cannula of the blood pump through the incision and into a left ventricle of a heart; positioning a tip of a guidewire into an aorta, distal to an aortic valve; advancing the tip through the aortic valve and into the left ventricle; connecting the tip to the outflow cannula; pulling the blood pump with the guidewire to advance at least a portion of the outflow cannula through the aortic valve and into the aorta; securing the blood pump to the heart, the aorta, or both; disconnecting the tip from the blood pump; and removing the guidewire from the patient.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: August 1, 2017
    Assignee: HeartWare, Inc.
    Inventor: James Schuermann
  • Patent number: 9717832
    Abstract: An implantable blood pump includes an impeller rotatable about a rotational axis, having a body with a bottom surface at a downstream end and a central opening centered about the axis extending at least partially through the body from the bottom surface. A projecting element, e.g., a shaft, extends from below the bottom surface into or through the opening to support the impeller. The body can be configured to drive a primary downstream blood flow along an exterior of the body to beyond a peripheral edge of the bottom surface, and to provide a secondary downstream blood flow through the opening and along the bottom surface to beyond the peripheral edge, the secondary flow improving washing of a bearing surface.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: August 1, 2017
    Assignee: HeartWave, Inc.
    Inventors: Mustafa Ertan Taskin, Ellen Keysselitz, Wolfgang Kerkhoffs
  • Patent number: 9717833
    Abstract: An impeller includes a hub and a blade supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub. The impeller may be part of a pump for pumping fluids, such as blood, and may include a cannula having a proximal portion with a fixed diameter, and a distal portion with an expandable diameter. The impeller may reside in the expandable portion of the cannula. The cannula may have a compressed diameter which allows it to be inserted percutaneously into a patient. Once at a desired location, the expandable portion of the cannula may be expanded and the impeller expanded to the deployed configuration. A flexible drive shaft may extend through the cannula for rotationally driving the impeller within the patient.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: August 1, 2017
    Assignees: THE PENN STATE RESEARCH FOUNDATION, TC1 LLC
    Inventors: Mark W. McBride, David A. Boger, Robert L. Campbell, Gregory P. Dillon, Stephen A. Hambric, Robert F. Kunz, Boris Leschinsky, Thomas M. Mallison, James P. Runt, Justin M. Walsh
  • Patent number: 9717834
    Abstract: Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: August 1, 2017
    Assignee: DEKA Products Limited Partnership
    Inventors: Michael J. Wilt, Dirk A. van der Merwe, Todd A. Ballantyne, Kevin L. Grant, Jonathan P. Rosse, Catharine N. Flynn, Brian K. Yee
  • Patent number: 9717835
    Abstract: The present disclosure describes a blood oxygenator that includes a checkerboard layout of fluid (e.g., blood) and gas (e.g., oxygen) channels. When viewed as a cross-section through each of the channels of the oxygenator, the checkerboard configuration includes alternating gas and fluid channels in both the x-axis (e.g., in-plane) and in the y-axis (e.g., out-of-plane) directions. The oxygenator described herein reduces manufacturing complexity by using first, second, and third polymer layers that include asymmetrical channel designs. The channel designs include “open” gas channels, which are exposed to the ambient atmosphere. The oxygenator is placed within a pressure vessel to drive gas into each of the open gas channels, which in some implementations, negates the need for a gas manifold.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: August 1, 2017
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Jeffrey T. Borenstein, Ernest Kim, Joseph L. Charest, Alla Epshteyn, Abigail Spencer, James Truslow
  • Patent number: 9717836
    Abstract: Disclosed herein are methods, systems and devices to monitor vascular volume status utilizing at least one oximetry/photoplethysmography sensor. The methods, systems and devices provide an alternative to conventional vascular volume monitoring methods while enabling reliable, non-invasive, and automatic monitoring of vascular volume to avert patient hypotension. The methods, systems and devices may be employed in the context of both inpatient and outpatient facilities and may also be incorporated into conventional monitoring devices, techniques and equipment.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: August 1, 2017
    Assignee: University of Florida Research Foundation, Inc.
    Inventor: Richard J. Melker
  • Patent number: 9717837
    Abstract: A dialysis machine includes a dialyzer (1), a dialysate feed system (5) having a feed line (52), and a discharge system (6) having a discharge line (62). The machine further includes ultrafiltration control elements (UF) and back-filtration control elements (RF). The feed line is provided with a constriction (520) and with elements for measuring the pressure difference (523, 524) across the terminals of the constriction. The feed system further includes a ventricle bag (50), and pressurizer elements (70) for putting the ventricle bag (50) under pressure. The machine further includes an open/close system (C5, C5?) for opening/closing the discharge line (62) and the back-filtration control elements cause the discharge line (62) to close, and control the pressure applied to the ventricle bag (50), as a function of the pressure difference measured across the terminals of the constriction (520), so as to obtain a given flow rate of dialysate.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: August 1, 2017
    Assignee: PHYSIDIA
    Inventor: Eric Vincent
  • Patent number: 9717838
    Abstract: A method and system for collecting leukoreduced red blood cells employing a spinning membrane separator including a housing having an upper end region and a lower end region in an operating position with a red blood cell outlet in the upper end region of the housing and a whole blood inlet in the lower end region of the housing. The method and system provide for flowing additive solution into the whole blood inlet of the housing to prime the separator; flowing whole blood into the whole blood inlet of the housing; separating red blood cells from the whole blood; flowing separated red blood cells out of the red blood cell outlet of the housing; combining the separated red blood cells with additive solution: passing the separated red blood cells and additive solution combination through a leukoreduction filter; and collecting the filtered red blood cells and additive solution.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: August 1, 2017
    Assignee: Fenwal, Inc.
    Inventors: Benjamin Kusters, Christopher Wegener, Kyungyoon Min
  • Patent number: 9717839
    Abstract: An extracorporeal blood circulator includes a control unit and a speed manipulation section. A rotation display section displays a lower limit rotation setting value of a pump motor in accordance with a command of the control unit. The lower limit rotation speed setting value is a minimum rotation speed for preventing backflow of blood inside a circulation circuit A manually adjusted speed setting request from the manipulation section controls the pump speed, except that the controller enforces the lower limit speed setting unless receiving confirmation from a manipulator.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: August 1, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Tomoaki Hashimoto
  • Patent number: 9717840
    Abstract: One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Extracorporeal blood treatment systems draw blood at such a high rate that a loss of integrity in the blood circuit can be serious. There are a number of mechanisms for detecting and preventing leaks, but none is perfect. This tends to limit the use of such equipment in unsupervised settings, such as the home will be limited. Some leak detection schemes can be made sensitive enough to detect the barest of leaks, but when this is done, they result in too many false positives. The invention combines information from multiple inputs to enhance sensitivity in leak detection and reduce the problem of false positives.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: August 1, 2017
    Assignee: NXSTAGE MEDICAL, INC.
    Inventors: Jeffrey H. Burbank, James M. Brugger
  • Patent number: 9717841
    Abstract: The present invention relates to a method and apparatus for the isolation, modification and re-administration of a molecule or biomolecule, or a class of biomolecules, from the body fluid of a mammal via an extracorporeal closed circuit device. The device is able to capture and modify the biomolecule by the covalent or non-covalent attachment of a secondary molecule or protein, by cross-linking the captured molecule, or by altering the structure of the molecule (for example, by deglycosylation, peptide cleavage, or aggregation). The apparatus can be used to return the modified molecule or biomolecule to the mammalian subject. The device and methods may be utilized for the patient-specific diagnosis and/or treatment of a disease state which presents an associated molecule or protein in plasma or any other fluidized physiological system.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 1, 2017
    Inventor: Gary L. McNeil
  • Patent number: 9717842
    Abstract: Systems and methods for the washing and processing of biological fluid/biological cells are disclosed. The systems and methods utilize a disposable fluid circuit including a spinning membrane separation device to wash the biological cells.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: August 1, 2017
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Christopher Wegener
  • Patent number: 9717843
    Abstract: A system and method are provided for packaging and sterilizing analyte sensors. The packaging system provides a structure for securing the analyte sensors in a fixed position and fixed orientation within the package.
    Type: Grant
    Filed: February 9, 2015
    Date of Patent: August 1, 2017
    Assignee: DexCom, Inc.
    Inventors: Minda McDorman Grucela, Jinsong Gao
  • Patent number: 9717844
    Abstract: A cabinet structure for an infusion system includes a platform, on which the system is mounted, and a shell surrounding an interior space, which contains at least a portion of the system. The shell preferably includes an opening that is sized and oriented to allow a lowering of a radioisotope generator, for the system, into the interior space, and a lifting of the generator out from the interior space. The shell may further include another opening, located at a higher elevation than the aforementioned opening, in order to provide access to a waste bottle of the infusion system.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: August 1, 2017
    Assignee: Bracco Diagnostics Inc.
    Inventors: Charles R. Quirico, Ernest Balestracci, Jacob S. Childs, Peter B. Madson, Daniel V. Clements, Janet L. Gelbach
  • Patent number: 9717845
    Abstract: A medical therapy system for delivering at least two therapies based on a geographic location of the medical therapy system is disclosed. The medical therapy system includes an infusion pump having a case that contains a processor, memory, a drive mechanism, a reservoir, a radio, and a sensor suite. The sensor suite includes a global positioning system (GPS) receiver to determine a location of the infusion pump. The processor receives the location of the infusion pump and executes first instructions stored in the memory. The processor executes second instructions stored in the memory only when the location of the infusion pump is within a safe zone defined around specified GPS coordinates.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: August 1, 2017
    Assignee: MEDTRONIC MINIMED, INC.
    Inventor: Emilian Istoc
  • Patent number: 9717846
    Abstract: Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: August 1, 2017
    Assignee: Medtronic, Inc.
    Inventors: Dennis M. Skelton, Jon P. Davis, Keith A. Miesel, Timothy J. Denison
  • Patent number: 9717847
    Abstract: Apparatus for delivering a quantity of fluid to bone marrow of a bone or providing access to remove fluids from a target site is provided. The apparatus may include a driver, a plunger operating and cartridge assembly mechanism, a cartridge assembly having a fluid reservoir and a bone penetrating needle.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: August 1, 2017
    Assignee: TELEFLEX MEDICAL DEVICES S.ÀR.L.
    Inventors: Larry J. Miller, David S. Bolleter, Charles M. Schwimmer, Robert A. Wilk
  • Patent number: 9717848
    Abstract: A medical therapy system to deliver a pre-bolus volume of medicant is disclosed. The medical therapy system includes an infusion pump that has a case containing a processor, memory, a drive mechanism, a reservoir, communication hardware and a sensor system. The infusion pump further includes a global positioning system (GPS) receiver to determine GPS coordinates of the infusion pump. The GPS receiver is coupled to the processor that executes stored program instructions to provide notification for confirmation to deliver a pre-bolus volume from the reservoir when the GPS coordinates of the infusion pump are within a specified proximity of GPS coordinates of a saved location.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: August 1, 2017
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Eric P. Geismar, Francine R. Kaufman
  • Patent number: 9717849
    Abstract: Some embodiments of an infusion pump system may include an occlusion sensor that can be used to detect when an occlusion exists in the fluid path between the medicine reservoir and the infusion site on the user's skin. Such an occlusion may occur, for example, when the fluid flow line (e.g., a cannula, infusion set tubing, or the like) is kinked. If the medicine dispensation path to the user is occluded, the user may receive no dosage or a lower dosage of the medicine. As such, the occlusion sensor can be used to indicate when the fluid is flowing or not flowing, thereby permitting the infusion pump system to communicate an alarm to the user if an occlusion exists.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: August 1, 2017
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Amit Mhatre, Jian Yao Wu, Mitchell Wenger, Steven A. Friedman
  • Patent number: 9717850
    Abstract: A device (100) for delivering a medicament into a patient's body by injection into or through the patient's skin, including: a main body having a bottom enclosure (104) that has a top surface including a button guide latch (268); a reservoir (160) disposed within the main body for containing the medicament; an injection needle (152) for penetrating the skin of the patient, the needle (152) having a lumen and communicating with the reservoir (160) when the device (100) is activated; a pressurizing system (140, 144) for pressurizing the reservoir (160) when the device (100) is activated; and an activator button (128) movably disposed on the main body and movable from a pre-activated position to an activated position. The activator button (128) includes an activation arm (228). When the activator button (128) moves from the pre-activated position to the activated position, an end of the activation arm (228) engages with the button guide latch (268) and prevents return movement of the activator button (128).
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: August 1, 2017
    Assignee: Becton, Dickinson and Company
    Inventor: Ralph Sonderegger
  • Patent number: 9717851
    Abstract: An autoinjector having a lower body receiving a tank containing fluid product and a piston and a needle. The autoinjector including a central body fastened to the lower body and an actuating sleeve provided with a contact end that contacts the body of the user, the actuating sleeve moveable between a projected position and an actuation position. The actuating sleeve is in a projected position prior to and after actuation of the autoinjector, an injection mechanism is provided to inject the fluid product through the needle when the needle is in an injection position in which it is inserted in the body of the user. The autoinjector includes a tank movement device to move the needle towards the injection position, the tank movement device triggering the injection mechanism only after the needle has reached its injection position.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: August 1, 2017
    Assignee: APTAR FRANCE SAS
    Inventors: David Fabien, Antoine Mansencal, Matthieu Walter
  • Patent number: 9717852
    Abstract: A cartridge holder for a drug delivery device is presented having snap fastening connection means to fasten the cartridge holder to a housing of the drug delivery device, wherein the fastening connection means are provided with at least on basically rectangular window for receiving a locking element of said housing. The invention is further directed to a pen-type injector equipped with a respective snap fastening connection for the cartridge holder.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: August 1, 2017
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventor: Robin Einwachter
  • Patent number: 9717853
    Abstract: A cylinder-piston unit of a needle-free injector, with at least one cylinder accommodating an injection solution, at least one piston, and an adhesive coating arranged in the area of the free end face of the cylinder. The cylinder has a bottom portion, on which a discharge tube is arranged. An adhesive disc, which is displaceable in the direction of the center line of the cylinder-piston unit between an installation position and an application position, is arranged on the discharge tube and/or on the bottom portion. The adhesive disc has an adhesive coating on each of the two end faces. In the installation position, the discharge tube can be sealed off in the adhesive disc. In the application position, the front edge of the discharge nozzle lies in the plane of the front adhesive coating or protrudes beyond this plane by at least 0.5 mm.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: August 1, 2017
    Assignee: LTS LOHMANN THERAPIE-SYSTEME AG
    Inventor: Rudolf Matusch
  • Patent number: 9717854
    Abstract: An adapter for a syringe includes a base portion having an insertion hole and a flange portion extending laterally outwardly from the base portion. A longitudinal axis of the flange portion extends from a first distal end to an opposing second distal end. A first distance measured from a geometric center of the insertion hole to the first distal end of the flange portion is less than a second distance measured from the geometric center of the insertion hole to the second distal end. The first distance defines a first section of the flange portion and the second distance defines a second section of the flange portion. The first section has a cross-sectional shape that is one of at least slightly concave and at least slightly convex and the second section has a cross-sectional shape that is the other of at least slightly convex and at least slightly concave.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: August 1, 2017
    Assignee: West Pharmaceutical Services, Inc.
    Inventors: Christopher Evans, Brian Costello, Christopher Gieda
  • Patent number: 9717855
    Abstract: An adapter for use with a drug delivery device having a reservoir for containing a product, the reservoir having a distally projecting end-piece defining a passageway for the transfer of the product from the reservoir, includes a collar engageable with the end-piece, an adaptor securing member limiting translational movement of the collar with respect to the end-piece once the collar is engaged with the end-piece, at least one adaptor anti-rotation member limiting the rotation of the collar with respect to the end-piece once the collar is engaged with the end-piece, at least one deactivating member neutralizing the adaptor anti-rotation member in response to a turning torque equal or greater than a predetermined value applied to the collar when the collar is engaged with the end-piece, thereby allowing the rotation of the collar with respect to the end-piece.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: August 1, 2017
    Assignee: Becton Dickinson France
    Inventors: Michel Bosshardt, Benoit Guillard
  • Patent number: 9717856
    Abstract: An injection apparatus includes a counter wheel that is incremented by the dose delivery mechanism each time the device is fired. The apparatus includes a final dose disabling mechanism that prevents further usage once the final dose has been delivered. An anti-tamper feature is provided to prevent inadvertent or premature initialisation of the apparatus.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: August 1, 2017
    Assignee: OWEN MUMFORD LIMITED
    Inventors: Clive Nicholls, Robert Michael Wozencroft, Jeremy Marshall
  • Patent number: 9717857
    Abstract: The invention relates to a medical injection device comprising a container body (1) and a stopper (2) in gliding engagement within the container body (1) for expelling a fluid (3) through an opening of said container body (1), wherein: —at least the distal portion (20) of the stopper (2) that is in contact with the fluid (3) is made of a thermoplastic polyolefin, —the stopper (2) further comprises at least one O-ring (4, 4?) maintained in at least one peripheral groove (210, 210?), —said O-ring (4, 4?) is made of a butyl-type rubber; and —the cross-section of said peripheral groove (210, 210?) is designed so as to compress both axially and radially the O-ring (4) when said O-ring (4) is engaged in the peripheral groove (210) between the stopper (2) and the inner wall (10) of the container body (1).
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: August 1, 2017
    Assignee: Becton Dickinson France
    Inventor: Romain Lanier
  • Patent number: 9717858
    Abstract: A gasket for prefilled syringe according to the present invention is a gasket for prefilled syringe that includes a fluid contacting portion, a sliding portion with a circumferential surface, a film layer made of a fluororesin coated on the fluid contacting portion and sliding portion and further, and a coating layer including trimethylsiloxysilicate laminated on the film layer covering the sliding portion.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: August 1, 2017
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Seiji Hara, Hiroaki Nakano, Hiroyuki Kaneko, Yasuhiko Kondo
  • Patent number: 9717859
    Abstract: A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.
    Type: Grant
    Filed: July 23, 2016
    Date of Patent: August 1, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Harms, Steffen Raab, Dominic George Webber, James Robert Howarth, Trevor John Beckett, Geoffrey Philip Gray, John David Cross
  • Patent number: 9717860
    Abstract: An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: August 1, 2017
    Inventors: Michel Bruehwiler, Cole Constantineau, Ryan Schoonmaker, James Bates, Robert Banik, Margaret Taylor
  • Patent number: 9717861
    Abstract: A syringe (211) includes a syringe body (217) for receiving and administering a medicament. A needle (215) is received by the syringe body (217). A needle adjusting member (221) is movably disposed on the syringe body (217) between first and second positions. When the needle adjusting member (221) is in the first position, the needle (215) has a first length adapted to draw medicament into the syringe body (217). When the needle adjusting member (221) is in the second position, the needle (215) has a second length for injecting the medicament.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: August 1, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Robert Banik, James Bates
  • Patent number: 9717862
    Abstract: The present invention relates in one aspect to an infusion fluid warmer which comprises a casing shell having an upper wall structure and a lower, opposing, wall structure. The casing shell encloses a fluid channel or passage extending through the casing shell in-between the upper and lower wall structures and fluid inlet and outlet ports coupled to opposite ends of the fluid channel or passage to allow a flow of infusion fluid through the casing shell. A housing shell is formed in a thermally conducting and electrically insulating material and a heating element is bonded to the housing shell and thermally coupled thereto. The fluid channel or passage extends through the housing shell or extends around the housing shell such that heat energy is transferred to the infusion fluid by direct physical contact with housing shell material.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: August 1, 2017
    Assignee: Mequ ApS
    Inventor: Ulrik Krogh Andersen
  • Patent number: 9717863
    Abstract: The invention is related to an apparatus comprising a dispense interface comprising a lockout element for use with a drug delivery device, the lockout element comprising at least one spring component removeably maintained in a respective first position such that when the dispense interface is first attached and then removed from said drug delivery device, each spring component moves into a respective second position, which respective second position is configured to prevent said dispense interface from being reattached to a drug delivery device.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: August 1, 2017
    Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
  • Patent number: 9717864
    Abstract: A dispense interface for use with a drug delivery device with an inner body and with a lockout element. The lockout element is coupled to the inner body movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device. In the locked condition, the dispense interface is not-attachable to the drug delivery device. The lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: August 1, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
  • Patent number: 9717865
    Abstract: The present invention relates to a fluid delivery system that comprises a fluid container having a chamber structured to hold a fluid therein and a delivery device operable to control delivery of a fluid from the chamber of the fluid container. The fluid container includes a geometric mating member extending from an outer surface thereof. The delivery device includes a geometric mating receptacle structured to mate with at least a portion of the geometric mating member of the fluid container to verify compatibility of the fluid container with the delivery device. Alternatively or additionally, the fluid container may include a first data fixture component and the delivery device may include a second data fixture component that cooperates with the first data fixture component of the fluid container to verify compatibility of the fluid container with the delivery device.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 1, 2017
    Assignee: ADMETSYS CORPORATION
    Inventors: Jeffrey W. Valk, Timothy W. Valk
  • Patent number: 9717866
    Abstract: An improved inhalation device is provided for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device includes a staple assembly comprising a plunger and staple that are securely and robustly coupled to one another. Embodiments of the inhalation device have a cap that prevents or reduces the amount of dust and grime entering into the device. The cap is additionally configured to prevent or reduce inadvertent and unintentional operation of the device. The body portion and first casing portion of certain embodiments of the inhalation device are sealably coupled, restricting or reducing undesirable flow pathways that have an adverse effect on the operation of the device.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: August 1, 2017
    Assignee: Civitas Therapeutics, Inc.
    Inventors: Colleen Ellwanger, Brian Noble, Chuck Ganem, Jake Ganem, Kevin Stapleton
  • Patent number: 9717867
    Abstract: In a first aspect, the invention relates to a method for operating an aerosol inhalation device (10), comprising the steps of transporting a certain amount of an aerosol to a desired location outside said device (10) and vibrating the transported aerosol when it has reached said desired location. In a second aspect, the invention relates to an aerosol inhalation device (10) comprising a pump (1) for flowing a certain amount of an aerosol to a desired location outside the device (10), a vibrator (2) for vibrating the transported aerosol in a vibration mode and a control configured to actuate the vibrator (2) for vibrating the flowed aerosol only when it has reached said desired location.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: August 1, 2017
    Assignees: PARI GmbH Spezialisten für effektive Inhalation, PARI Pharma GmbH
    Inventors: Martin Luber, Andreas Boehm, Uwe Schuschnig, Axel Krüner