Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion. The catheter further comprises at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.

Abstract: The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon. The implant may be configured to have a generally D-shaped configuration when initially implanted, but to assume a generally circular form when subjected to an outward force such as that provided by a dilation balloon.

Abstract: Devices, apparatus, and methods for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. In particular, a target and capture device is provided for guiding a cerclage traversal catheter system through a cerclage trajectory, particularly through a reentry site of the cerclage trajectory. The target and capture device provides the user with a target through which the cerclage traversal catheter system must be guided, particularly under imaging guidance, so as to properly traverse the cerclage trajectory at any desired location, particularly at a reentry site. The target and capture device can, further, ensnare and externalize the cerclage traversal catheter system.

Abstract: Devices and methods provide enhanced treatment of a cardiac valve annulus. Methods generally involve contacting an anchor delivery device with the valve annulus and releasing a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus. Anchors, which in some embodiments are super-elastic or shape memory self-securing anchors, are then drawn together to tighten the annulus. Devices generally include an elongate catheter having a housing at or near the distal end for releasably housing a plurality of coupled anchors. The housing may be flexible, may conform to a valve annulus, and in some embodiments may be coupled with an expandable member to enhance contact of the housing with annular tissue. In one embodiment, self-securing anchors lie approximately flat within the delivery device housing, allowing anchors with relatively large deployed shapes to be housed in and deployed from a relatively narrow delivery device.

Abstract: Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over the movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

Abstract: A medical implant porous scaffold structure having low modulus, wherein said structure is formed by multiple basic units superposed sequentially along the three-dimensional directions in three-dimensional space, each of the basic units is composed of a quadrangular prism or hexagonal prism having central interconnected pores encircled by four or six side walls, each of the side walls is composed by a “X-type” frame structure formed by two crossed ribs, and the central interconnected pores of the adjacent basic units arranged along the axis direction of the quadrangular prism or the hexagonal prism are interconnected to each other.

Abstract: An implant assembly comprising a bone augment and an articulating member. The bone augment includes a bone-engaging surface and a coupling surface. The articulating member is configured to couple with the bone augment.

Abstract: A separate nub component between the plate and an intervertebral fusion cage, wherein the nub is attached to the plate. The nub lessens the undesired pivotal movement of the plate. It is believed that when the nub fits snugly between the endplates of the adjacent vertebral bodies, it acts as a stop against the undesired pivotal movement of the plate.

Abstract: A patient-specific porous metal prosthesis and a method for manufacturing the same are provided. The orthopaedic prosthesis may be metallic to provide adequate strength and stability. Also, the orthopaedic prosthesis may be porous to promote bone ingrowth.

Abstract: A joint prosthesis includes first and second articulated corresponding joint components implantable within a body of a patient, wherein the corresponding joint components have corresponding surfaces that are relatively displaceable with respect to each other over a predefined functional range of motion of the corresponding joint components. The corresponding joint components each comprise one or more magnetic elements creating gradient magnetic fields having relatively strongest and weakest field areas over different portions of each of the corresponding surfaces, wherein the gradient magnetic fields are strongest in attraction at positions of the corresponding surfaces which align when the corresponding surfaces are at a boundary of the predefined functional range of motion, and deter joint dislocation by deterring relative movement of the corresponding surfaces beyond the boundary.

Abstract: An implant for a femoral head of a patient. The implant includes a shell implantable on the femoral head of the patient and correcting a defect of the femoral head. The shell is designed preoperatively to have a patient-specific first surface for articulation with the patient's acetabulum and a patient-specific periphery mateable with a periphery of the defect. The shell caps the defect and the first surface of the shell is continuous to a remaining healthy surface of the femoral head. The defect can be a bone defect, a cartilage defect or a combination thereof.

Abstract: This invention relates to orthopaedic implants having one or more regions of three dimensional lattice that substantially replicate the trabecular orientation within a healthy bone from the same anatomical location as the implant. A method for the manufacture of such orthopaedic implants is also disclosed using additive manufacturing techniques and patient-specific anatomical information.

Abstract: An implant device used to replace and restore the function of the knee meniscus in a human. The compliant, yet resilient device is comprised of a biocompatible, non-degradable three-dimensional body comprised of at least a central body, a second structure, a third structure, and a coating. The device is concentrically aligned wherein the second structure is adjoined to the central body wherein the third structure is adjoined on the central body opposite of the second structure. The third structure further features a first and a second pulling element which is coupled to the central body and forms the outer periphery and major circumference of the device. The device is comprised of multiple components which provide tensile strength, compressive resilience, and attachment mechanisms for replacing the meniscus. Each structure is comprised of multiple surfaces which are further reinforced, separated, and connected by an individual plurality of vertical elements.

Abstract: An implant (30) for a mammalian bone joint (3) for spacing a first bone (2) of the joint from a second bone (1) of the joint while allowing translational movement of the second bone in relation to the first bone is described. The implant comprises (a) a distal part (31) configured for intramedullary engagement with an end of the second bone, (b) a proximal part (34) having a platform (15) configured for non-engaging abutment of an end of the first bone and translational movement thereon, and (c) an articulating coupling (10, 16) provided between the distal and proximal ends allowing controlled articulation of the first and second bones. The bone-abutting platform is shaped to conform to and translate upon the end of the first bone. A kit for assembly to form the implant of the invention, and the use of the implant to treat osteoarthritis in a bone joint, are also described.

Abstract: Embodiments of the present disclosure relate to devices and methods for treating one or more damaged, diseased, or traumatized portions of the spine, including intervertebral discs, to reduce or eliminate associated back pain. In one or more embodiments, the present disclosure relates to an expandable interbody spacer. The expandable interbody spacer may comprise a first jointed arm comprising a plurality of links pivotally coupled end to end. The expandable interbody spacer further may comprise a second jointed arm comprising a plurality of links pivotally coupled end to end. The first jointed arm and the second jointed arm may be interconnected at a proximal end of the expandable interbody spacer. The first jointed arm and the second jointed arm may be interconnected at a distal end of the expandable interbody spacer.

Abstract: A two part annulus repair rivet for repairing a defect in the annulus of an intervertebral disc includes a first part delivered through a port and adapted to be positioned at an internal surface of an annulus adjacent a defect and a second part adapted to be positioned on an external surface of the annulus adjacent the defect. The first and second parts are secured together, repairing the defect.

Abstract: A spinal interbody implant has a bone screw retention mechanism that prohibits bone screws from backing out after the bone screws are installed. A bone screw retention plate is received in a plate retention area of the implant to provide a barrier that keeps the installed bone screws from backing out of their bone screw pocket. The bone screw retention mechanism consists of a retention plate and a configured plate retention area in a face of the implant body. Retention plate fasteners may be used to retain the configured plate. In one form, the bone screw retention mechanism consists of a retention plate, a configured plate retention area in a face of the implant body, and a retention plate bolt. In another form, the bone screw retention mechanism consists of a retention plate, a configured plate retention area in a face of the implant body, and a retention plate bolt.

Abstract: An expandable fusion device may include a first endplate and a second endplate. The expandable fusion device may also include first and second ramps configured to mate with both the first and second endplates. An inserter instrument includes an outer shaft having a bore extending longitudinally therethrough and an inner shaft extending through the bore in the outer shaft. The outer shaft is configured to engage the first or second opening in the second ramp, and the inner shaft is configured to engage the corresponding first or second opening in the first ramp to control implant height and/or lordotic angle.

Abstract: An expandable implant includes a top support configured to engage a first portion of vertebral bone, a bottom support configured to engage a second portion of vertebral bone, and a control assembly coupled to the top support and the bottom support and configured to control relative movement between the top support and the bottom support. The control assembly includes a control member including a head and a body portion. The head includes a recess and the body portion includes at least one access port in fluid communication with the recess to enable delivery of fluid to an interior of the implant via the recess and at least one access port.

Abstract: An expandable implant includes a top support assembly defining an upper surface configured to engage a first portion of vertebral bone; a bottom support assembly defining a lower surface configured to engage a second portion of vertebral bone; and a control assembly coupled to the top support assembly and the bottom support assembly and configured to control relative movement between the top support assembly and the bottom support assembly between a collapsed position and an expanded position. In the collapsed position, the upper surface is generally parallel to the lower surface, and in the expanded position, a portion of the upper surface extends at an acute angle relative to a portion of the lower surface.

Abstract: A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning.

Abstract: The present invention involves a system and methods for assembling and implanting a vertebral body implant. The vertebral body implant includes, but is not necessarily limited to, an expandable core body and endplates that can be attached at both ends. Endplates of various shapes, sizes and angles are attachable to the expandable core so that a suitable vertebral body implant can be implanted between vertebrae.

Abstract: An interbody fusion implant fits between adjacent vertebrae for fixation during fusion thereof. Upper bores extend into a cephalid surface of the implant and preferably include threads therein. A guide tool is removably attachable to the implant which supports guide bores along centerlines aligned with the upper bores in the implant. A drill can pass along these guide bores to form holes in a vertebra adjacent the cephalid surface of the implant which is precisely aligned with the upper bores. A hybrid screw then passes through these holes in the vertebra adjacent the cephalid surface and threads into the upper bores to secure the implant to the adjacent cephalid vertebra. Bone screws can also be used to secure the implant to caudal vertebra by passing through bores passing through the implant, such that the implant is securely mechanically fastened to both cephalid and caudal vertebrae adjacent the implant.

Abstract: The present invention is directed to a deployment system for an endoluminal device. The deployment system includes a confining sheath placed around a compacted endoluminal device. A deployment line is provided in the system. As the deployment line is actuated, the sheath retracts from around the compacted endoluminal device. Once the sheath is retracted from around the compacted endoluminal device, the endoluminal device is operable to expand. Any remaining sheath material is removed from the implantation site along with the deployment line.

Abstract: A drainage stent delivery system including an elongate shaft of a medial device, a drainage catheter or stent, and an interference fit member for selectively coupling the drainage stent to the elongate shaft. The drainage stent is selectively coupled to a distal portion of the elongate shaft by an interference fit between the interference fit member and the drainage stent such that axial movement of the elongate shaft relative to the drainage stent moves the interference fit member from a first position in which the interference fit member is engaged with the drainage stent and forms an interference fit with the drainage stent to a second position in which the interference fit member is disengaged from the drainage stent.

Abstract: An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system. Methods of deploying the stent with the delivery system are also disclosed.

Abstract: The present disclosure relates to the field of weight loss. Specifically, the present disclosure relates to systems and methods for reducing daily caloric loads by limiting the delivery of long chain fatty acids into the bloodstream. More specifically, the present disclosure relates to systems and methods for reducing or restricting the flow of chylomicron lipids from the cysterna chyli through the thoracic duct into the bloodstream.

Abstract: An apparatus for gastric bypass is disclosed. The apparatus for gastric bypass includes a primary passage having an input and an output. The apparatus also includes a bypass conduit, coupled to the primary passage, having an input and an output, wherein the passage input is interspersed with the conduit input. The apparatus further has a primary regulator coupled to the primary passage and adjustable to control a primary flow profile from the input to the output of the primary passage. The apparatus also has a bypass regulator coupled to the bypass conduit and adjustable to control a bypass flow profile from the input to the output of the bypass conduit.

Abstract: A gastric tube for use in a bariatric surgical procedure includes an elongate tube and a movable component supported on an outer surface of the elongate tube. The elongate tube has a non-circular cross section along at least a portion of a length of the elongate tube. The movable component is movable between an unexpanded configuration and an expanded configuration. In the unexpanded configuration, the movable component is disposed in abutting engagement with the outer surface of the elongate tube. In the expanded configuration, the movable component bows outwardly from the outer surface of the elongate tube.

Abstract: A joint movement supporting protection device, comprising a joint protection body (1) matched with a joint in shape, and a fixing device (2) connected or contacted with the joint protection body (1) and tightly attaching the joint protection body (1) to a joint of a human body. A plurality of upper notches (11) extending downwards from top but not penetrating through bottom are formed in a portion, close to a joint movement area, of the joint protection body (1). Thus, the joint protection body (1) is divided into a plurality of joint pieces (12). A junction of the upper notch (11) and a lower edge of the joint protection body (1) serves as a rotation fulcrum (13) between adjacent joint pieces (12). When the joint bends to a limiting position, the two adjacent joint pieces (12) on two sides of the upper notch (11) contact.

Abstract: A shoulder orthosis includes a shoulder therapy device adapted to provide treatment to a shoulder joint of a person, and a flexion/extension device. The flexion/extension device positions the shoulder joint in at least one of greater than 0 degrees of flexion and greater than 0 degrees of extension concurrently with the shoulder therapy device providing the treatment to the shoulder joint. In one example, the shoulder therapy device may be an abduction/adduction device and/or an internal/external rotation device.

Abstract: Systems and methods are provided for supporting an arm of a user using a harness configured to be worn on a body of a user; and an arm support coupled to the harness configured to support an arm of the user, the arm support configured to accommodate movement of the arm while following the movement without substantially interfering with the movement of the user's arm. One or more compensation elements may be coupled to the arm support to apply an offset force to at least partially offset a gravitational force acting on the arm as the user moves and the arm support follows the movement of the user's arm, the one or more compensation elements providing a force profile that varies the offset force based on an orientation of the arm support.

Abstract: A reinforced support strap and method of application on a joint provides lateral and medial support to a joint and limbs. The support strap comprises, in some embodiments, a resilient body portion having a generally elongated V-shape that encapsulates the joint and is manipulated through rotation or axial movement along the joint and limbs for an enhanced fit. The body portion comprises a base end, an open end, and a pair of termini. The body portion further includes a mount surface that overlays the joint, and an exterior surface. The mount surface adheres to the joint through the use of a fastening mechanism. A reinforcement member, having less resilience than the body portion, may integrates into the body portion through stitching, to provide enhanced stability.

Abstract: A knee brace with a connection mechanism that enables quick and easy secure attachment and detachment of a plastic cuff shell to struts of the brace without the need for separate fasteners and the tools required for them via the use of a novel snap connector which will connect by a simple plug in motion, and which is configured to firmly hold the connected strut and prevent it from rotating relative to the cuff shell once connected while also enabling a quick and easy tool-free disconnection of the strut for exchanging of one cuff for another. The thigh and tibia shells can be interchange without removing any screws, rivets or traditional connectors providing a modular construction with the ability to mix and match different size thigh and calf shells, making it possible for a customer to order the product in kit form, or as separate components thereby enabling easy customization.

Abstract: A conformable body interface includes a body scaffold comprising a three-dimensional lattice which can be removably placed over a three-dimensional soft-tissue surface, such as a knee, elbow, spine, ankle, wrist, hip, or neck. One or more sensors are located at one or more locations on the body scaffold, and the one or more locations are selected to position the sensor near a target region on the body surface when the body scaffold is placed over the three-dimensional body surface. Typically, the sensors are positioned near a body joint to detect motion of the body joint.

Abstract: A particle filled neck brace is used for immobilizing the neck and chin of a patient and includes a vacuum pump disposed on the neck brace, which pump is communicated to the interior of the neck brace. After the neck brace is secured around the neck and chin of the patient, the vacuum pump is manipulated to remove air from the neck brace to form a rigid mold about the patient's neck and chin. The vacuum pump has a one way directional valve so that the neck brace remains in a rigid configuration for as long as the neck brace is applied to the patient. The neck brace also specifically forms a rigid mold over the patient's chin so as to immobilize the patient as well as to provide a comfortable fit without inducing further distracting the patient or restricting the patient's venous return blood flow.

Abstract: A vacuum therapy apparatus includes a vacuum chamber configured to receive an organ to be treated, a vacuum pump coupled to the vacuum chamber and configured to draw air from the vacuum chamber so that blood is drawn into the organ, a controller configured to cause the vacuum pump to undergo an operating cycle in which the organ is changed from a flaccid to an erectile state and then back to an flaccid state, causing tissues of the organ to expand and contract, and a memory provided on a detachable part of the apparatus and configured to store information regarding at least one operating cycle under which the apparatus has operated.

Abstract: Disclosed is an ostomy wafer comprising a central peristomal area surrounding a stoma receiving hole, from which a plurality of petals are extending radially, the petals being interconnected via bridges with a apex pointing away from the central area. The wafer is suitable for application to especially demanding skin surface conditions, such as in ostomists suffering from hernia.

Abstract: An ostomy appliance (10) including first and second walls (12, 14) connected to each other at or near their peripheries, the first wall having a stoma-receiving opening (16), and a waste collecting cavity defined between the first and second walls, wherein the second wall includes an outlet (20) which communicates with the cavity, and wherein the appliance includes a blocking member (50) moveable between a first position in which the outlet is blocked or substantially blocked and a second position in which the outlet is unblocked or substantially unblocked.

Abstract: A urinal includes a urinal body, a urine receiving reservoir and a spout extending therefrom for receiving urine. A supplemental urinal spout is provided and comprises both an inlet portion and a retention portion, the supplemental urinal spout being attachable to the spout of the urinal to form a leak prevention seal. Opposing tabs are provided to aid in attaching the spout to the urinal. The supplemental urinal spout comprises a funnel-shaped element that is integrally formed with a cylindrical sidewall. The urinal body is preferably made of a plastic material and the supplemental urinal spout is made from a low durometer elastomeric material. The urinal and the supplemental urinal spout may be disposable.

Abstract: The present invention relates to a control and command method for a device for thermal stimulation of animal or human tissue (1), said method being characterised in that it includes: determining a neutral temperature applied to the tissue (1), thermally adjusting the neutral temperature by activating a control loop, determining a cold or hot thermal stimulation temperature to be applied to the tissue (1), in alternation with the neutral temperature; determining a duration and a frequency of the thermal stimulations; in the case of an instruction to initiate the stimulation temperature by activating a control loop and by deactivating the control loop on the neutral temperature; and synchronising a physiological recording with the thermal stimulation.

Abstract: The present invention relates to a transportable therapy device for the therapeutic treatment of at least one person, in particular of a painful condition of at least one limb of the person, comprising a box-like housing which encloses at least one cold chamber which is only accessible from outside via at least one opening, the at least one opening being formed and arranged in the housing in such a way to introduce a limb, which is to be treated, into the cold chamber, comprising at least one cooling means which is thermally coupled in such a way to the cold chamber to cool the cold chamber and is configured in such a way to generate in the cold chamber a predetermined temperature for the therapeutic treatment of the limb which has been introduced, in particular for the therapeutic treatment of a painful condition of the limb which has been introduced.

Abstract: A medical cooling device for reducing the body core temperature of a patient and a method for operating the same are provided. The cooling process provided by the medical cooling device is based on the state or degree of shivering of the patient.

Abstract: A medical cooling device and a method for operating the same are provided.

Abstract: An apparatus and method for treating a head injury including head gear and at least one cooling medium. The cooling medium has a prolonged cooling effect to aid injured persons recovery and health after sustaining a head injury. The apparatus and method is also contemplated for use with headaches, migraines, heat and/or sun stroke, as well as persons that have suffered a stroke.

Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.

Abstract: An eyedropper is provided for administering a predetermined volume of liquid onto the surface of an eye. The eyedropper includes a body having a nozzle in fluid communication with the internal cavity of the reservoir body. Projecting from an inner surface of the reservoir body are a first projecting portion having a first contact surface and a second projecting portion having a second contact surface. The first contact surface and the second contact surface are disposed opposite from one another and are spaced apart from one another. In use, the first and second contact surfaces limit the displacement volume of the internal cavity when the eyedropper is squeezed thereby limiting the volume of liquid expelled from the nozzle.

Abstract: One embodiment is directed to a method for interfacing an ophthalmic intervention system with an eye of a patient, comprising: placing a patient interface assembly comprising a housing, an optical lens coupled to the housing, and an eye engagement assembly coupled to the housing, the eye engagement assembly comprising an inner seal and an outer seal, into contact with the eye of the patient by sealably engaging the eye with the inner and outer seals in a vacuum zone defined between the inner and outer seals; applying a vacuum load between the inner and outer seals to engage the eye using the vacuum load; and physically limiting an amount of distension of the eye in the vacuum zone.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: A treatment method is provided that includes an introduction step of introducing a transparent stent into a vitreous body of an eyeball, an expansion step of causing the stent to expansively deform inside the vitreous body to bring a retina into contact with a retinal pigment epithelium, and a placement step of placing the stent in the vitreous body with the stent keeping the retina in contact with the retinal pigment epithelium.