Patents Issued in August 22, 2017
  • Patent number: 9738827
    Abstract: The present invention is directed to a method of preparing a carbon quantum dot. The carbon quantum dot can be prepared from a carbon precursor, such as a fullerene, and a complex metal hydride. The present invention also discloses a carbon quantum dot made by reacting a carbon precursor with a complex metal hydride and a polymer containing a carbon quantum dot made by reacting a carbon precursor with a complex metal hydride.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: August 22, 2017
    Assignee: Savannah River Nuclear Solutions, LLC
    Inventors: Ragaiy Zidan, Joseph A. Teprovich, Aaron L. Washington
  • Patent number: 9738828
    Abstract: An optical converter for producing colored or white light from blue excitation light is provided. The converter has good scattering properties to be able to produce nearly white light from the scattered blue light components and the scattered, converted yellow light components. The optical converter includes material including one or more of a YAG ceramic, a LuAG ceramic, and a magnesium-aluminum ceramic exhibiting strong scattering.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: August 22, 2017
    Assignee: SCHOTT AG
    Inventors: Volker Hagemann, Peter Nass, Yvonne Menke, Bernd Hoppe, Wolfram Beier, Rainer Liebald, Niko Schultz, Guenter Weidmann, Hauke Esemann
  • Patent number: 9738829
    Abstract: Phosphors include a CaAlSiN3 family crystal phase, wherein the CaAlSiN3 family crystal phase comprises at least one element selected from the group consisting of Mn, Ce, Pr, Nd, Sm, Eu, Tb, Dy, Ho, Er, Tm, and Yb.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: August 22, 2017
    Assignees: MITSUBISHI CHEMICAL CORPORATION, National Institute for Materials Science, Nichia Corporation, Citizen Electronics CO., Ltd.
    Inventors: Naoto Hirosaki, Kyota Ueda, Hajime Yamamoto
  • Patent number: 9738830
    Abstract: Geopolymers are one type of aluminosilicate materials formed through the polymerization of silicate and aluminate tetrahedrons. Geopolymer is used as a non-calcium-based stabilizer to mix with sulfate-rich soils. The stabilized soils were exposed to deionized water for 7 days until the volume of soil samples reached constant. Volumetric expansion of the sulfate-rich soil samples stabilized with metakaolin based geopolymer was 7 times lower than those stabilized with lime while the mechanical strength of stabilized soil samples were significantly improved.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: August 22, 2017
    Assignee: Worcester Polytechnic Institute
    Inventors: Mingjiang Tao, Mo Zhang
  • Patent number: 9738831
    Abstract: A liquid crystal composition is described, containing a chiral agent and achiral component T containing at least one compound 1 having an unsubstituted or methyl group-substituted dioxane ring and having at least one —COO— or —CF2O— as a connecting group, and exhibiting an optically isotropic liquid crystal phase.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: August 22, 2017
    Assignees: JNC CORPORATION, JNC PETROCHEMICAL CORPORATION
    Inventors: Shin-Ichi Yamamoto, Koki Sago, Yasuhiro Haseba
  • Patent number: 9738832
    Abstract: A flame retardant block copolymer is prepared from renewable content. In an exemplary synthetic method, a bio-derived flame retardant block copolymer is prepared by a ring opening polymerization of a biobased cyclic ester and a phosphorus-containing polymer. In some embodiments, the biobased cyclic ester is lactide. In some embodiments, the phosphorus-containing polymer is a hydroxyl-telechelic flame retardant biopolymer prepared by a polycondensation reaction of a biobased diol (e.g., isosorbide) and a phosphorus-containing monomer (e.g., phenylphosphonic dichloride). In other embodiments, the phosphorus-containing polymer is synthesized from a dioxaphospholane monomer.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: August 22, 2017
    Assignee: International Business Machines Corporation
    Inventors: Dylan J. Boday, Joseph Kuczynski, Timothy C. Mauldin
  • Patent number: 9738833
    Abstract: A two-stage reactor is disclosed for the conversion of solid particulate biomass material. The reactor is designed to maximize conversion of the solid biomass material, while limiting excess cracking of primary reaction products. The two-stage reactor comprises a first stage rector, in which solid biomass material is thermally pyrolyzed to primary reaction products. The primary reaction products are catalytically converted in a second stage reactor.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: August 22, 2017
    Assignee: Inaeris Technologies, LLC
    Inventors: Michael Brady, Ronald Lee Cordle, Peter Loezos, Dennis Stamires
  • Patent number: 9738834
    Abstract: An alternative process and device for carrying out Fischer Tropsch (FT) syntheses is proposed, allowing the reactant entities that take part in the FT reaction to be activated and their contributions, whether by quantity or by proportion, to be adjusted. The process consists in making a particulate phase, optionally consisting of catalytic particles, flow through a reactor. While flowing through the reactor, the particulate phase is subjected at regular intervals to the action of a plasma obtained from a gas, such as hydrogen, thus enabling hydrogen activation for hydrogenation of carbon monoxide, or carbon monoxide activation in order to lengthen the carbon chains.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: August 22, 2017
    Inventor: Nicolas Gilbert Ugolin
  • Patent number: 9738835
    Abstract: The invention relates to a process for performing a Fischer Tropsch reaction in a reactor comprising at least two reactor tubes, a coolant chamber, and a gas distribution system below the coolant chamber, whereby at least two reactor tubes extend through the coolant chamber and one or more highly porous catalysts, said catalyst(s) having a size of at least 1 mm and comprising a porous body and a catalyst material, whereby the porous body has a porosity within the range of between 50 and 98 volume %.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: August 22, 2017
    Assignee: SHELL OIL COMPANY
    Inventor: Franciscus Johannes Maria Schrauwen
  • Patent number: 9738836
    Abstract: The liquid feed nozzle assemblies for a circulating fluid bed reactor comprise (i) a throttle body premixer to combine liquid feed with atomization steam to form a liquid feed/steam mixture comprising gas bubbles in liquid; (ii) a conduit connected to the premixer and to a discharge nozzle to convey a flow of the liquid/steam mixture created by the premixer to the nozzle body; (iii) a discharge nozzle connected to the flow conduit to shear the liquid feed/steam mixture to create liquid feed droplets of reduced size and (iv) a disperser at the outlet of the discharge nozzle to provide a spray jet of liquid feed having an increased surface area relative to a cylindrical jet. The nozzle assembles are particularly useful in fluid coking units using heavy oil feeds such a tar sands bitumen.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: August 22, 2017
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Kevin Reid, Jennifer McMillan, Konstantin Pougatch, Martha E. Salcudean
  • Patent number: 9738837
    Abstract: The present disclosure provides a process and system for removing at least a portion of organosulfur compounds from an oil sands produced gas and transferring the organosulfur compounds to a bitumen-based liquid. One example of the system includes an absorber to contact the gas with an amount of liquid hydrocarbon sufficient to absorb some of the organosulfur compounds, producing an organosulfur enriched liquid hydrocarbon. The system includes a separator that accepts the organosulfur enriched liquid hydrocarbon and an emulsion that includes water and the bitumen-based liquid. The separator separates produced water from a bitumen-based mixture of organosulfur enriched liquid hydrocarbon and bitumen-based liquid. The system adds an amount of additional liquid hydrocarbon to separate the produced water from the bitumen-based mixture when the amount of liquid hydrocarbon added is less than the amount of liquid hydrocarbon needed to separate the produced water from the bitumen-based mixture.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: August 22, 2017
    Assignee: Cenovus Energy, Inc.
    Inventors: Kelly M. Bell, Russell H. Wickes
  • Patent number: 9738838
    Abstract: Provided is an improved hydroprocessing process allowing one to realize superior isoselectivity. The process comprises contacting a feed comprised of normal hydrocarbons under hydroprocessing conditions with a catalyst comprising delaminated SSZ-70. The delaminated SSZ-70 has been found to provide unexpected improvements in the catalysis of hydroprocessing hydrocarbons. Delaminated SSZ-70 offers a zeolite layer with a single unit cell of thickness in one dimension, allowing an elimination of mass transfer in comparison with non-delaminated SSZ-70.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: August 22, 2017
    Assignee: Chevron U.S.A. Inc.
    Inventors: Bi-Zeng Zhan, Stacey Ian Zones, Christopher M. Lew
  • Patent number: 9738839
    Abstract: This invention relates to the conversion or hydrotreatment of petroleum or coal derived liquids in a novel ebullated-bed reactor system. The novel processing scheme results in a much simpler and less costly (investment and annual operating) ebullated-bed reaction system through the elimination of the high pressure, high temperature separator, hydrogen purification plant, and recycle gas compressor as well as a smaller hydrogen make-up compressor all resulting in substantial operational and construction efficiency.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: August 22, 2017
    Assignees: IFP ENERGIES NOUVELLES, AXENS
    Inventor: James J. Colyar
  • Patent number: 9738840
    Abstract: A method of processing raw oil sands material that includes bitumen. The method includes, in a predistillation process, heating the raw oil sands material to between approximately 535° C. and at least approximately 600° C. to at least partially vaporize the bitumen, to provide atmospheric gas oil and vacuum gas oil from the bitumen, and to provide coked oil sands material that includes carbon-heavy hydrocarbons and sand. The coked oil sands material is heated to approximately 900° C., to produce a dry barren hot oil sands material and syngas including hydrogen and carbon monoxide gases. Heat energy is transferred from at least a portion of the barren hot oil sands material to the raw oil sands material.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: August 22, 2017
    Assignee: Lakes Environmental Research Inc.
    Inventors: Jesse Thé, Roydon Andrew Fraser, Mohammad Hossein Ordouei
  • Patent number: 9738841
    Abstract: A gasified gas production system of the present disclosure includes a gasification furnace which produces a gasified gas by gasifying a gasification raw material, a flow passage through which the gasified gas produced in the gasification furnace flows, a catalyst-holding unit which holds a catalyst which promotes reforming of tar included in the gasified gas inside the flow passage, and an oxidation agent supply unit which supplies an oxidation agent with a temperature of 200° C. to 900° C. to the catalyst.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: August 22, 2017
    Assignee: IHI Corporation
    Inventor: Hiroaki Ohara
  • Patent number: 9738842
    Abstract: There is described a process and an apparatus for purifying a mixture and related products. In particular, there is described a process and an apparatus for purifying a mixture comprising fats, oils and greases as are typically found in sewer waste. The process involves heating, acidifying and separating the mixture. The apparatus used includes a heating and separation device for separating into a solid fraction, an organic liquid fraction and an aqueous liquid fraction. Apparatus such as a three phase separation unit and a rotary vacuum filter may also be used.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: August 22, 2017
    Assignee: Argent Energy (UK) Limited
    Inventor: Michael Scott
  • Patent number: 9738843
    Abstract: A method for making high density fuels including, heating a renewable plant oil, triglyceride, or fatty acid with at least one first acid catalyst to generate a first mixture of alkyladamantanes, increasing reaction time or adding at least one second catalysts to a first mixture of alkyladamantanes to produce a second alkyladamantane mixture, separating methyl, ethyl, propyl, and/or butyl adamantanes from a second alkyladamantane mixture to produce a third adamantane mixture to produce fuels.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: August 22, 2017
    Assignee: The United States of America as Represented by the Secretary of the Navy
    Inventor: Benjamin G. Harvey
  • Patent number: 9738844
    Abstract: A method of manufacturing a molded solid fuel including: a pulverization for pulverizing low-grade coal; a mixing for obtaining a slurry by mixing the pulverized low-grade coal and a solvent oil; a dehydration for obtaining a dehydrated slurry by heating and dehydrating the slurry; a solid-liquid separation for obtaining a cake by separating the solvent oil from the dehydrated slurry; a drying for obtaining powdery modified coal by heating the cake and further separating the solvent oil from the cake; and a molding for pressurizing and molding the powdery modified coal by using a molding machine, without the addition/mixture of a binder. In the molding, a coolant is sprayed onto the surface of the molding machine, and the surface temperature of the molding machine is kept equal to or below 100° C.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: August 22, 2017
    Assignee: Kobe Steel, Ltd.
    Inventors: Yoichi Takahashi, Takuo Shigehisa, Tsuyoshi Adachi
  • Patent number: 9738845
    Abstract: A combustible pellet drying system includes a valveless pulse combustor and a drying column. The drying column includes a first drying region and optionally a second drying region. The first drying region receives heated drying gas from the pulse combustor to dry a quantity of moist pellets flowing downwardly through the drying column. Moisture-laden exhaust gas from the first drying region is processed by a condenser to remove water and recover thermal energy therefrom, and to produce a cooled dried exhaust gas which may be reheated by passing through a jacket around the pulse combustor. The reheated dry gas is introduced into the second drying region to further dry the pellets. The second drying region is preferably a downwardly expanding cone configuration. The drying column includes a plurality of temperature sensors. Adjacent temperature sensors may be used to determine a level of pellets within the drying column. The combustible pellets are preferably coal pellets.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: August 22, 2017
    Assignee: OMNIS THERMAL TECHNOLOGIES, LLC
    Inventor: David S. Gibbel
  • Patent number: 9738846
    Abstract: Provided are: a solid lubricant having a low friction coefficient and excellent abrasion resistance; and a sliding member having this solid lubricant embedded therein. The solid lubricant (4) has a sea-island structure, comprising: a sea phase as a continuous phase, containing a hydrocarbon-based wax and a polyethylene resin; and an island phase as a dispersion phase, containing a low-molecular weight tetrafluoroethylene resin, a higher fatty acid salt, a phosphate of basic nitrogen-containing compound, and zinc stannate. A high-molecular weight tetrafluoroethylene resin is contained in this continuous-phase sea phase in a fibrous and mesh state. The hydrocarbon-based wax content is 30-60 vol %, the polyethylene resin content is 3-10 vol %, the low-molecular weight tetrafluoroethylene resin content is 10-30% vol %, the higher fatty acid salt content is 20-40% vol %, the basic nitrogen-containing compound phosphate content is 0.5-5 vol %, the zinc stannate content is 0.
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: August 22, 2017
    Assignee: OILES CORPORATION
    Inventors: Yoshiaki Yamamoto, Kentaro Okubo
  • Patent number: 9738847
    Abstract: Provided herein are compositions containing at least one estolide compound and at least one ene and/or Diels Alder compound. In certain embodiments, the addition of at least one ene and/or Diels Alder compound to an estolide-containing composition may improve the cold temperature, viscometric, and/or anti-wear properties of the composition.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: August 22, 2017
    Assignee: Biosynthetic Technologies, LLC
    Inventors: Jakob Bredsguard, Travis Thompson, Jeremy Forest
  • Patent number: 9738848
    Abstract: The present invention relates to a multifunctional lubricant composition which serves as a base oil for lubrication or as an additive for lubrication, including, with respect to 100 parts by mass of phosphorus compound (A) having a specific structure specified in the Description, 26 parts by mass to 43 parts by mass of phosphorus compound (B) having a specific structure specified in the Description, 0 parts by mass to 1.3 parts by mass of phosphorus compound (C) having a specific structure specified in the Description, and a total of 0 parts by mass to 1.3 parts by mass of triphenyl phosphate and tricresyl phosphate.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: August 22, 2017
    Assignee: ADEKA CORPORATION
    Inventors: Masahiro Takata, Kenji Yamamoto, Shoji Matsuda
  • Patent number: 9738849
    Abstract: The invention provides a lubricating composition containing (a) an oil of lubricating viscosity, (b) a phosphite having at least one hydrocarbyl group that has 4 or more carbon atoms, and (c) a compound derived from a hydroxy-carboxylic acid. The invention further relates to the use of the lubricating composition in an internal combustion engine.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: August 22, 2017
    Assignee: The Lubrizol Corporation
    Inventors: William R. S. Barton, Mark C. Davies, Michael R. Sutton, Matthew D. Gieselman, Patrick E. Mosier
  • Patent number: 9738850
    Abstract: Provided is a method for recovering oil from corn in an ethanol production process. The method comprises applying an alkoxylated glycerine ester of formula (I) to a corn-based product obtained from an ethanol production process.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: August 22, 2017
    Assignee: Ivanhoe Industries
    Inventor: Robert Wiese
  • Patent number: 9738851
    Abstract: The present invention provides a method for extracting lipids from microorganisms without using organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microorganisms by lysing cells and removing water soluble compound and/or materials by washing the lysed cell mixtures with aqueous washing solutions until a substantially non-emulsified lipid is obtained.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: August 22, 2017
    Assignee: DSM IP Assets B.V.
    Inventors: Craig M. Ruecker, Swithwin Patrick Adu-peasah, Brian S. Engelhardt, George T Veeder, III
  • Patent number: 9738852
    Abstract: A method of separating oil from a composition containing an oil and water emulsion, by adding a separation additive which is a fatty ester of alkoxylated glycerol, and performing at least one oil separation step. The method is particularly suitable for separating corn oil from stillage produced in a corn ethanol mill.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: August 22, 2017
    Assignee: Croda, Inc.
    Inventors: Min Ma Wang, Craig Michael Sungail, Xin Chen
  • Patent number: 9738853
    Abstract: Methods for making specialty chemical products and chemical intermediates using hydroformylation are generally disclosed. Further, compositions and compounds formed using such methods are also disclosed. In some embodiments, methods are disclosed for refining a renewably sourced material, such as a natural oil, to form compositions, which can be further reacted employing the methods disclosed herein to form certain specialty chemical products or chemical intermediates.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: August 22, 2017
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Thomas E. Snead, Demond L. Gildon, Steven A. Cohen, Leslie V. Beltran, Robin Weitkamp
  • Patent number: 9738854
    Abstract: The present invention pertains to the use of 3-(cyclohex-1-en-1-yl)propionates in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet waters, fabric care products, personal products, and the like, and in counteracting malodors.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: August 22, 2017
    Inventors: Anthony T. Levorse, Jr., Nicole L. Giffin
  • Patent number: 9738855
    Abstract: The disclosed apparatus, systems and methods relate to the conversion of high free fatty acid (“HFFA”) containing oils defined as oils containing 20-100% free fatty acids (“FFA”) and low free fatty acid (“LFFA”) containing oils defined as oils containing 1-20% free fatty acids (FFA) into oil with less than about 0.5-1% FFA. If the feedstock is HFFA oil, the process includes a combination of partial glycerolysis of HFFA oils to produce LFFA oils and subsequent stripping of LFFA oils to produce NFFA oils via steam distillation. If the feedstock is LFFA oil, the process includes stripping of LFFA oils to produce NFFA oils via steam distillation and subjecting FFA to partial glycerolysis to convert FFA to oil.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: August 22, 2017
    Assignee: Tehnochem
    Inventor: Sanjeev Agarwal
  • Patent number: 9738856
    Abstract: The disclosure relates to a silica-based structurant and methods of making such a structurant. According to one embodiment, the structurant may include 55 wt % to 90 wt % of a silica having a [Na2O]/[SiO2] molar ratio of from 0.02 to 0.14 and at least 15 wt % of an adjunct salt. The structurant may have a hydrated particle size distribution such that no more than 30 wt % of the structurant has a hydrated particle size greater than 45 micrometers according to the Structurant Residue Test. The structurant may also have a tapped bulk density of from 200 g/L to 300 g/L. Methods of making the structurant include combining starting materials with a non-stoichiometric amount of acid, then drying the reaction mixture without first washing any silica-based particles to produce a silica-based structurant with adjunct salt.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: August 22, 2017
    Assignee: PABEN PROYECTOS ESTRATEGICOS, S.A. DE C.V.
    Inventor: Enrique Hernandez
  • Patent number: 9738857
    Abstract: The present disclosure relates to compositions and methods for cleaning medical and dental instruments. The disclosed compositions are preferably non-foaming or generate low foam to allow visual inspection of the cleaning process as well as safe handling of the instruments. The disclosed compositions preferably employ select proteases, a carbonate and a nonionic surfactant.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: August 22, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Nathan R. Ortmann, Katherine Vetter, Thomas R. Mohs, Anthony W. Erickson
  • Patent number: 9738858
    Abstract: The current invention is directed towards mixtures of compounds, comprising (A) in the range of from 93 to 97% by weight compound of general formula (I) (B) in the range of from 3 to 6.5% by weight compound of general formula (II) (C) in the range of from 0.2 to 0.5% by weight compound of general formula (III) wherein the integers are defined as follows: R1 is —(CH2)nCH3, R2 is —(CH2)n+2CH3, R3 is —(CH2)n+1CH(CH3)2, R4 is —(CH2)n?1CH(CH3)2 G1 selected from monosaccharides with 4 to 6 carbon atoms, x in the range of from 1.1 to 10, n is a number in the range of from 1 to 4.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: August 22, 2017
    Assignee: BASF SE
    Inventors: Frederic Bauer, Rainer Eskuchen, Juergen Tropsch
  • Patent number: 9738859
    Abstract: The present invention relates to water-dispersable microcapsules comprising an oil phase, e.g. a perfume, containing a photolabile ?-ketoacid or ?-ketoester capable of generating a gas upon exposure to light. The gas is able to cause an extension or the breaking of the microcapsule allowing the release of the oil phase and thus increasing the long-lastingness of the odor perception. The present invention concerns also the use of said microcapsules in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's microcapsules to provide a prolonged release of fragrant molecules.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: August 22, 2017
    Assignee: Firmenich SA
    Inventors: Andreas Herrmann, Damien Berthier, Nicolas Paret, Alain Trachsel
  • Patent number: 9738860
    Abstract: Methods and materials for making complex, living, vascularized tissues for organ and tissue replacement, especially complex and/or thick, structures, such as liver tissue is provided. Tissue lamina is made in a system comprising an apparatus having (a) a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, wherein the first and second molds or polymer scaffolds have means defining microchannels positioned toward the semi-permeable membrane, wherein the first and second molds or polymer scaffolds are fastened together; and (b) animal cells. Methods for producing complex, three-dimensional tissues or organs from tissue lamina are also provided.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: August 22, 2017
    Assignees: The General Hospital Corporation, The Charles Stark Draper Laboratory, Inc.
    Inventors: Joseph P. Vacanti, Young-Moon M. Shin, Jennifer Ogilvie, Alexander Sevy, Tomoyuki Maemura, Osamu Ishii, Mohammad R. Kaazempur-Mofrad, Jeffrey T. Borenstein, Kevin R. King, Chiao-Chun Wang, Eli Weinberg
  • Patent number: 9738861
    Abstract: A culture system has a culture bag for suspending and culturing pluripotent stem cells in a culture medium; a waste liquid container for storing used culture medium that is connected to the culture bag; a fresh medium container for storing a fresh culture medium that is connected to the culture bag; three-way stopcocks for switching flow channels from the culture bag to the waste liquid container or the fresh culture medium container, etc.; a trap portion for trapping the pluripotent stem cells in the culture medium in the flow toward the waste liquid container side; and a filter portion for subculturing that is formed in fourth and fifth flow channels in parallel to a first flow channel. The first flow channel connects the trap part to the culture bag, and has a mesh by which a cell mass of the pluripotent stem cells can be divided. A pump is used to pump the liquid in the individual flow channels.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: August 22, 2017
    Assignees: KYOTO UNIVERSITY, Nipro Corporation
    Inventors: Norio Nakatsuji, Yoshihiro Yoshikawa, Masakatsu Takeuchi, Daiki Tateyama
  • Patent number: 9738862
    Abstract: A bioreactor apparatus includes a vessel establishing an interior space environmentally separable from an exterior space outside of the vessel, an agitation system including mixing means arranged in the interior space and drive means adapted to rotate the mixing means. The drive means includes a drive motor that is arranged in the interior space.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: August 22, 2017
    Assignee: LUONNONVARAKESKUS
    Inventors: Yrjo Virtanen, Vesa Joutsjoki
  • Patent number: 9738863
    Abstract: The present invention relates to a bioreactor including at least one reactor vessel in form of a plastic bag, a tray (4) for holding said at least one bag, a rocking device for limited rocking motions of the tray (4) around a rocking axis (2). According to the invention the bioreactor comprises a device (6,7,8,9) for enabling swinging of the tray (4) around a second axis (7) parallel to and distanced from the rocking axis (2).
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: August 22, 2017
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Andreas Andersson, Johan L. Carlsson, Christian Elnegard, Henrik K. Eriksson, Thomas Falkman, Patric Fricking, Linnea Pauler, Claes Petterson
  • Patent number: 9738864
    Abstract: A device (10) for detecting the presence of at least one microorganism in the contents (101, 201) of a container (100, 200) comprising a wall with a translucent zone, said detection device (10) comprising: a) at least one light source (11), such as a light-emitting diode (LED), capable of illuminating the contents of the container (100, 200) by emitting an excitation light beam through the translucent zone of the container (100, 200); b) at least one detection means (12, 13, 14, 15), such as a photodiode, for detecting at least one reaction light beam emitted in response to the illumination of the contents (101, 201) of the container (100, 200); said at least one light source (11) and said at least one detection means (12, 13, 14, 15) being equipped with at least one connection means (105, 205), to connect said at least one light source (11) and said at least one detection means (12, 13, 14, 15) to the wall of the container (100, 200), in the translucent zone, said at least one detection means (12, 13, 14
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: August 22, 2017
    Assignee: Biomerieux
    Inventors: Bruno Colin, Corinne De La Foata, Jacques Dachaud, Fabienne Made
  • Patent number: 9738865
    Abstract: This invention provides a simple fermentation apparatus which is able to work in a standard pressure. Moreover, it can continuously produce liquid fermentation products automatically in a large amount without filtering. The fermentation apparatus is able to be configured in large farms. The use of it has become simple and convenient.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: August 22, 2017
    Assignee: ADVANCED GREEN BIOTECHNOLOGY INC.
    Inventor: Chien-Yi Liu
  • Patent number: 9738866
    Abstract: Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: August 22, 2017
    Assignee: FloDesign Sonics, Inc.
    Inventors: Bart Lipkens, Erik Miller, Benjamin Ross-Johnsrud, Walter M. Presz, Jr., Kedar Chitale, Thomas J. Kennedy, III, Lauren Winiarski
  • Patent number: 9738867
    Abstract: A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: August 22, 2017
    Assignee: FloDesign Sonics, Inc.
    Inventors: Bart Lipkens, Louis Masi, Stanley Kowalski, III, Walter M. Presz, Jr., Jason Dionne, Brian Dutra, Ari Mercado, Thomas J. Kennedy, III, Arthur Martin
  • Patent number: 9738868
    Abstract: In the present invention, a photobioreactor and process for producing and harvesting microalgae involves a vessel for cultivating microalgae that is at least partially transparent to admit light into the vessel. At least a portion of the transparent part of the vessel is coated with a transparent conductive oxide (TCO) layer. The TCO layer is transparent to visible light necessary for algae growth, but is opaque to infrared light thereby reducing thermal heating load in the photobioreactor. The TCO layer also acts as an electrode, which when combined with a counter-electrode can provide a potential difference across at least a portion of the interior of the vessel between the TCO layer and the counter-electrode. The electrode arrangement can be utilized in an electrochemical process (e.g. electrodeposition and/or electroflotation) to dewater and harvest the microalgae in the same apparatus as the microalgae was cultivated.
    Type: Grant
    Filed: July 4, 2012
    Date of Patent: August 22, 2017
    Assignee: National Research Council of Canada
    Inventor: Farid Bensebaa
  • Patent number: 9738869
    Abstract: Described is a method for the culture of microalgae, comprising: providing a consortium of at least two living species of microalgae; culturing under illumination the consortium in a controllable bioreactor and under non-sterile aqueous culture conditions; and controlling the culture conditions for affecting at least one of the following output: (i) flocculation and/or settling of said consortium of microalgae; and (ii) adhesion of the microalgae to surfaces of the bioreactor; wherein said culture conditions are controlled to promote (i) and/or to minimize (ii), without adversely affecting growth of the consortium of microalgae. It is also possible to control the culture conditions for affecting iii) the protein, carbohydrate, and/or fat content of the said microalgae consortium. A system for carrying out the method is also described.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: August 22, 2017
    Assignees: CENTRE DE RECHERCHE INDUSTRIELLE DU QUEBEC, INSTITUT NATIONAL D'OPTIQUE
    Inventors: Yann Le Bihan, Marc Daigle, Paul Grenier, Marc Levesque
  • Patent number: 9738870
    Abstract: A method for treating a skin disorder, e.g., acne, e.g. acne vulgaris, in a subject is provided. The method comprises administering, e.g., applying, e.g., topically administering, ammonia oxidizing bacteria, e.g., a preparation comprising ammonia oxidizing bacteria, to a surface of the subject. Preparations comprising ammonia oxidizing bacteria for treating such skin disorder, e.g., acne, e.g. acne vulgaris in a subject are also provided.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: August 22, 2017
    Assignee: AOBIOME LLC
    Inventors: David R. Whitlock, Spiros Jamas, Larry Weiss
  • Patent number: 9738871
    Abstract: A method of extracting organelles from cells includes following process. A plurality of cells and a solution are mixed uniformly to obtain a mixture. The mixture is loaded into a container. The container is placed in a milling device comprising a miller and a mechanical power source connected to the miller. The miller is immersed into the mixture within the container. The mixture is milled by the miller to obtain a homogenized mixture, wherein a milling parameter is provided to the milling device, and the mechanical power source drives the miller according to the milling parameter. The homogenized mixture is centrifuged to obtain a supernatant. The supernatant is centrifuged to obtain a precipitate with a plurality of organelles. In the process that the mixture is milled by the miller, at least a part of the miller is kept in the mixture.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: August 22, 2017
    Assignee: TAIWAN MITOCHONDRION APPLIED TECHNOLOGY CO., LTD.
    Inventors: Chia-Wen Lin, Hsin-Ting Tsai, Han-Chung Cheng
  • Patent number: 9738872
    Abstract: An isolated population of cells comprising non-GVHD inducing anti-third party cells having a central memory T-lymphocyte (Tcm) phenotype is provided. The cells being tolerance-inducing cells and capable of homing to the lymph nodes following transplantation. Methods of generating same, use of same and methods of treatment are also provided.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: August 22, 2017
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yair Reisner, Eran Ophir, Yaki Eidelstein, Esther Bachar-Lustig
  • Patent number: 9738873
    Abstract: The nuclear reprogramming of somatic cells with mRNA encoding reprogramming factors is shown to be greatly accelerated by activation of innate immune responses in the somatic cell. Methods of activating innate immunity include activation of PKR, of toll-like receptors, e.g. TLR3, etc. In some embodiments the mRNA provides the activator of innate immunity.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: August 22, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: John P. Cooke, Eduard Yakubov
  • Patent number: 9738874
    Abstract: The present invention relates to isolated polypeptides having laccase activity and polynucleotides encoding the polypeptides and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: August 22, 2017
    Assignee: Novozymes Inc.
    Inventors: Ye Liu, Lan Tang, Junxin Duan, Yu Zhang
  • Patent number: 9738875
    Abstract: The invention relates to a genetically engineered bacterium comprising an energy-generating fermentation pathway and methods related thereto. In particular, the invention provides a bacterium comprising a phosphate butyryltransferase (Ptb) and a butyrate kinase (Buk) (Ptb-Buk) that act on non-native substrates to produce a wide variety of products and intermediates. In certain embodiments, the invention relates to the introduction of Ptb-Buk into a C1-fixing microoorgansim capable of producing products from a gaseous substrate.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: August 22, 2017
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Rasmus Overgaard Jensen, James Bruce Yarnton Haycock Behrendorff, Ryan Edward Hill
  • Patent number: 9738876
    Abstract: Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: August 22, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith A. Bauer, Ellen Fiss, David Harrow Gelfand, Edward S. Smith, Shawn Suko, Thomas W. Myers