Patents Issued in August 31, 2017
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Publication number: 20170247616Abstract: An apparatus for raising and lowering a cutting tool within a decoking drum, a decoking system and a method of raising and lowering a decoking system cutting tool. Instead of using metallic ropes, chains, or a self-propelled gear-based approach, non-metallic belts are secured at respective ends to a crosshead and one or more counterweights to enable vertical movement of the crosshead that in turn permits vertical movement of the cutting tool throughout the height of the drum. A motorized pulley system controls the movement of the belt, and preferably avoids having the motor be carried by the crosshead. The belts on each pulley are preferably arranged as cooperative sets so that within each set, both primary load belts and secondary load belts are present.Type: ApplicationFiled: September 30, 2015Publication date: August 31, 2017Applicant: Flowserve Management CompanyInventors: Daniel O. Arzuaga, Hrishikesh Raghunath Gadre
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Publication number: 20170247617Abstract: Aromatic compounds are prepared from a feed stream comprising biomass or a mixture of biomass and synthetic polymer in a process, comprising: a) subjecting the feed stream to a pyrolysis treatment in the presence of a cracking catalyst to yield a vaporous fraction comprising hydrocarbons with olefinic unsaturation and oxygen containing organic compounds and coke-laden cracking catalyst; b) separating the vaporous fraction from the coke-laden cracking catalyst; c) contacting the vaporous fraction with a second, aromatization catalyst in a conversion treatment to yield a conversion product comprising aromatic compounds; and d) recovering aromatic compounds from the conversion product, wherein the cracking catalyst is a naturally occurring material, selected from the group consisting of inorganic salts, refractory oxides, minerals, industrial rock and mixtures thereof.Type: ApplicationFiled: September 25, 2014Publication date: August 31, 2017Inventors: Niels Jan SCHENK, Arnold BIESBROEK, André HEERES, Hero Jan HEERES
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Publication number: 20170247618Abstract: Provided is a thermal decomposition method that allows efficient thermal decomposition of an organic substance such as a plastic to produce gas and oil with high heating value and with which a large amount of the organic substance can be processed. The method includes mixing the organic substance with an organic substance decomposition catalyst, forming the mixture to produce a composite agglomerated material, and thermally decomposing the organic substance by placing the composite agglomerated material in a thermal decomposition furnace. The maximum catalytic effect can be obtained since the organic substance and the catalyst are close to each other in the composite agglomerated material. Since the catalyst has thermal conductivity higher than that of the organic substance, the temperature rising rate of the organic substance can be increased.Type: ApplicationFiled: July 30, 2015Publication date: August 31, 2017Applicant: JFE STEEL CORPORATIONInventors: Jun Ishii, Katsuhiko Takagi, Koichi Momono, Minoru Asanuma
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Publication number: 20170247619Abstract: The present disclosure provides a process for preparing a hydrocarbon fuel from waste rubber. The process involves admixing, in a reaction vessel, at least one fluid medium with the waste rubber to obtain a slurry; wherein the concentration of the waste rubber in the slurry ranges from 45% to 70%. A reactor is charged with the slurry and a predetermined amount of at least one catalyst composition to obtain a mixture, followed by introduction of hydrogen to the reactor to attain a predetermined pressure and heating the mixture at a predetermined temperature, to attain an autogenously generated pressure, and for a predetermined time period to obtain a reaction mass comprising the hydrocarbon fuel. This reaction mass comprising the hydrocarbon fuel is then cooled to obtain a cooled reaction mass. The hydrocarbon fuel is then separated from the cooled reaction mass.Type: ApplicationFiled: May 16, 2017Publication date: August 31, 2017Applicant: RELIANCE INDUSTRIES LIMITEDInventors: Kshudiram MANTRI, Mandan CHIDAMBARAM, Ramesh BHUJADE, Nagesh SHARMA, Raksh Vir JASRA
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Publication number: 20170247620Abstract: A process and plant for conversion of a feed hydrocarbon stream to liquid hydrocarbon products in a small scale GTL plant, comprising the use of a cryogenic air separation unit (ASU), optionally together with vacuum pressure swing adsorption (VPSA), an autothermal reformer (ATR) or catalytic partial oxidation (CPO), and pressure swing adsorption (PSA) unit to produce a synthesis gas for downstream Fischer-Tropsch (FT) synthesis for production of liquid hydrocarbons.Type: ApplicationFiled: May 17, 2017Publication date: August 31, 2017Inventor: Thomas Sandahl Christensen
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Publication number: 20170247621Abstract: Disclosed is a process for the regeneration of an adsorber (A1). The adsorber (A1) is regenerated by contact with a gaseous stream (S2) and the outflow of the adsorber (A1) comprising condensate of stream (S2) and organic composition (OC1) collected in a device. After regeneration of the adsorber (A1) the stream (S2) in the adsorber (A1) is replaced completely or at least partially by the content of the device. Then the adsorber (A1) is fed with organic composition comprising at least one olefin, at least one alkane and at least one compound containing oxygen and/or sulfur.Type: ApplicationFiled: October 9, 2014Publication date: August 31, 2017Applicant: BASF SEInventors: Hans-Guenter WAGNER, Christoph BAYER, Lothar KARRER, Sven CRONE, Markus EGGERSMANN, Kam Wing WONG, Patrik PIETZ, Heinz RUETTER
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Publication number: 20170247622Abstract: Embodiments provide a method of compound removal from a fluid. The method includes contacting one or more metal organic framework (MOF) compositions with a fluid and sorbing one or more compounds, such as CO2, H2S and condensable hydrocarbons. One or more of CO2, H2S and condensable hydrocarbons can be sorbed simultaneously or in series. The metal organic framework can be an M-soc-MOF.Type: ApplicationFiled: August 25, 2015Publication date: August 31, 2017Inventors: Mohamed EDDAOUDI, Youssef BELMABKHOUT
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Publication number: 20170247623Abstract: A process of making a fuel product from spent grain from a beer brewing process. In the brewing process, the grain is pulverized to a particle size whose mean particle size is approximately 0.25 mm to 0.6 mm with less than 1% greater than 2 mm. After the brewing sugars are extracted from the grain, the spent grain is pressed against a filter to reduce moisture below sixty-five percent (65%), and then the grain is dried to further reduce its moisture to less than ten percent (10%). The dried spent grain, after the aforementioned processing, is fed into a combustion chamber for a steam boiler that is used for beer brewing, and the spent grain is separated during combustion by agitation such as spraying of the grain in the combustion chamber.Type: ApplicationFiled: October 28, 2015Publication date: August 31, 2017Applicant: AKBEV GROUP, LLCInventors: Geoffrey L. Larson, Brandon Michael Smith, Curtis Holmes, David D. Wilson
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Publication number: 20170247624Abstract: A composition of fuel additives includes at least a first additive having a partial ester derivative of polyols and a second additive having a quaternary ammonium salt. The first additive includes at least 50% by mass of a compound A selected from the partial esters of polyols and saturated or unsaturated, linear or branched, cyclic or acyclic C4 to C36 monocarboxylic aliphatic hydrocarbarbons, the partial esters being able to be used alone or in a mixture. The disclosure also relates to a diesel fuel including such a composition and the use of the fuel for limiting the deposits in a diesel engine. In particular, the disclosure relates to the use of the fuel containing the composition of additives of the present disclosure in direct-injection diesel engines.Type: ApplicationFiled: February 17, 2015Publication date: August 31, 2017Applicant: TOTAL MARKETING SERVICESInventors: Géraldine PAPIN, Thomas DUBOIS, Julien GUEIT
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Publication number: 20170247625Abstract: [Technical Problem] An object is to provide a sliding system which can achieve both the reduced friction and the enhanced wear resistance by means of a novel combination of a sliding film and a lubricant oil. [Solution to Problem] The sliding system of the present invention comprises: a pair of sliding members having sliding surfaces that can relatively move while facing each other; and a lubricant oil interposed between the sliding surfaces facing each other. At least one of the sliding surfaces comprises a coating surface of a crystalline chromium carbide film. The lubricant oil contains an oil-soluble molybdenum compound that has a chemical structure of a trinuclear of Mo. When the chromium carbide film as a whole is 100 at %, the chromium carbide film contains 40-75 at % of Cr.Type: ApplicationFiled: January 27, 2017Publication date: August 31, 2017Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hiroyuki MORI, Mamoru TOHYAMA, Masaru OKUYAMA, Keiji HAYASHI, Naoya IKEDA
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Publication number: 20170247626Abstract: A lubricating oil including a lubricating oil base stock as a major component; and a mixture of (i) one or more protected lubricating oil additives having a first performance function, and (ii) one or more unprotected lubricating oil additives having a second performance function, as a minor component. The first performance function and the second performance function are the same. The one or more protected lubricating oil additives are inactive with respect to their performance function. The one or more protected lubricating oil additives are converted into one or more unprotected lubricating oil additives in the lubricating oil in-service in an engine or other mechanical component. A method for controlled release of one or more lubricating oil additives into a lubricating oil. A method for improving oxidative stability of a lubricating oil and extending performance life of one or more lubricating oil additives.Type: ApplicationFiled: February 7, 2017Publication date: August 31, 2017Inventors: Man Kit Ng, Anne Marie Shough, Hong Cheng, Joseph R. Pellettiere, Peter Calcavecchio, Shane Deighton
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Publication number: 20170247627Abstract: A lubricating oil composition and method of operating a boosted internal combustion engine. The lubricating oil composition is formulated to be resistant to turbocharger deposit formation in the boosted internal combustion engine, as shown by its ability to ensure a TCO Temperature Increase of less than 9.0% as measured using the 2015 version of the General Motors dexos1® Turbocharger Coking Test. The lubricating oil composition may also have a low NOACK volatility, as measured by the method of ASTM D-5800 at 250° C.Type: ApplicationFiled: January 18, 2017Publication date: August 31, 2017Applicant: Afton Chemical CorporationInventors: Kongsheng Yang, Kristin Fletcher, William Y. Lam, Jeremy Styer
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Publication number: 20170247628Abstract: The invention provides a method of lubricating a 2-stroke marine diesel cylinder liner with a lubricating composition having a total base number of 10 to 25 mg KOH/g. The invention further provides a lubricating composition for lubricating the 2-stroke marine diesel cylinder liner.Type: ApplicationFiled: October 30, 2015Publication date: August 31, 2017Applicant: The Lubrizol CorporationInventors: Stephen J. Cook, Natasha K. Horn, Shaun P. Carney, Mark C. Davies, David M. Hobson
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Publication number: 20170247629Abstract: A lubricating oil including a lubricating oil base stock as a major component, and one or more lubricating oil additives having at least one protected active group, as a minor component. The one or more lubricating oil additives having at least one protected active group are converted into one or more lubricating oil additives having at least one unprotected active group in the lubricating oil in-service in an engine or other mechanical component. Compositions including one or more lubricating oil additives having at least one protected active group. A method for improving solubility of one or more lubricating oil additives in a lubricating oil. A method for improving oxidative stability of a lubricating oil and extending performance life of one or more lubricating oil additives. A method for improving friction control in an engine or other mechanical component lubricated with a lubricating oil.Type: ApplicationFiled: February 7, 2017Publication date: August 31, 2017Inventors: Man Kit Ng, Anne Marie Shough, Hong Cheng, Joseph R. Pellettiere, Peter Calcavecchio, Shane Deighton
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Publication number: 20170247630Abstract: A lubricating oil composition of the invention contains: a base oil; at least one of acid phosphate represented by formulae (1) and (2) below; and an antioxidant. In the above formulae: R1, R2 and R3 are alkyl groups; and at least one of R1 and R2 has 20 to 30 carbon atoms while R3 has 20 to 30 carbon atoms.Type: ApplicationFiled: May 22, 2015Publication date: August 31, 2017Applicant: IDEMITSU KOSAN CO., LTD.Inventor: Shuichi SAKANOUE
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Publication number: 20170247631Abstract: A self-lubricating composite material is disclosed. The self-lubricating composite material can include discontinuous polymer fiber segments dispersed within a woven matrix of semi-continuous thermoplastic fiber. The woven matrix can be embedded within a thermosetting resin. Also disclosed are methods of manufacturing the self-lubricating composite material.Type: ApplicationFiled: September 4, 2015Publication date: August 31, 2017Inventors: Michael KIM, Jon LAICOVSKY, Kashta RENNIE, Heitor SARRO, Andreas TRENKLER
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Publication number: 20170247632Abstract: An environmentally-improved motor oil blend and related methods for properly lubricating components of an engine and favorably modifying a plastic response of components of the engine, the blend being free of zinc di-alkyl-di-thiophosphates (ZDDP) and free of zinc di-thiophosphate (ZDTP), comprising: a motor oil selected from the motor oil group consisting of Group I, Group II, Group III, Group IV, and Group V motor oils; a motor oil additive comprising alpha-olefins and hydroisomerized hydro-treated severe hydrocracked base oil; ZDDP omitted from the chemical constituents of the motor oil; and ZDTP omitted from the chemical constituents of the motor oil.Type: ApplicationFiled: January 28, 2016Publication date: August 31, 2017Applicant: BestLine International Research, Inc.Inventor: Ronald J. Sloan
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Publication number: 20170247633Abstract: Disclosed herein is a method of using a water-based coolant for quenching or cutting a metal material. The water-based coolant is formed of: water; at least one inorganic acid salt selected from the group consisting of a carbonate, a hydrogen carbonate, a sesquicarbonate, a phosphate, a borate, a molybdate and a tungstate; a metal corrosion inhibitor; and optionally at least one of a bactericide, a water-soluble rust inhibitor, an antioxidant and a detergent dispersant.Type: ApplicationFiled: May 12, 2017Publication date: August 31, 2017Applicant: IDEMITSU KOSAN CO., LTD.Inventors: Mayu HASEGAWA, Masahisa GOTO, Katsumi ICHITANI, Kenro NOGUCHI
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Publication number: 20170247634Abstract: Wax compositions are provided with improved properties for candles and candle jars. The candle wax composition includes a major amount of a foots oil and minor amount of a 600N slack wax. In one form, the foots oil is a 150N foots oil that is included in the composition at from 70 to 80 weight % of the composition and the 600N slack wax is included in the composition at from 20 to 30 wt % of the composition. The candle wax composition provides substantially no oil bleed and a smooth surface appearance with improved burning properties in terms of soot production, wax consumption, melt pool depth and flame height.Type: ApplicationFiled: February 27, 2017Publication date: August 31, 2017Inventors: Elizabeth A. Turner, Federica Portoghese, Alan G. Blahey
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Publication number: 20170247635Abstract: Mixtures comprising a mixture of compounds (A), said mixture comprising a mixture of compounds according to the general formula (I) wherein R1 is C1-C4-alkyl, linear or branched, or hydrogen, R 2 is —CH2CH2R1, each G1 is glucose or xylose, wherein in the range of from 70 to 95% mole-% are glucose and from 5 to 30 mole-% are xylose, the average of x is in the range of from 1.1 to 4.Type: ApplicationFiled: August 12, 2015Publication date: August 31, 2017Applicant: BASF SEInventors: Frederic BAUER, Rainer ESKUCHEN
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Publication number: 20170247636Abstract: The present invention provides an aqueous liquid non-phosphate built domestic laundry whitening and brightening composition comprising charged surfactant, uncharged alkoxylated polyarylphenol and perfume.Type: ApplicationFiled: June 22, 2015Publication date: August 31, 2017Applicant: Conopco, Inc., d/b/a UNILEVERInventor: Stephen Norman BATCHELOR
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Publication number: 20170247637Abstract: The present invention relates to treatment compositions containing polymer systems that provide stability and benefit agent deposition as well as methods of making and using same. Such treatment compositions may be used for example as through the wash and/or through the rinse fabric enhancers as well as unit dose treatment compositions.Type: ApplicationFiled: May 5, 2017Publication date: August 31, 2017Inventors: Robert Richard DYKSTRA, Mark Robert SIVIK, Travis Kyle HODGDON, Stephanie Ann URBIN, Alessandro (NMN) CORONA, III, Jocelyn Michelle MCCULLOUGH, Denise Malcuit BELANGER, Kristi Lynn FLITER, Richard Timothy HARTSHORN, Nicholas David VETTER, Tessa XUAN, Reinhold Joseph LEYRER, Gledison FONSECA, Volodymyr BOYKO, Aaron FLORES-FIGUEROA
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Publication number: 20170247638Abstract: The present disclosure provides improved dye transfer inhibition in the washing of textiles by the use of urea derivatives comprising sulfonic or carboxylic acid groups.Type: ApplicationFiled: October 20, 2014Publication date: August 31, 2017Applicant: Henkel AG & Co. KGaAInventors: Mareile Job, Rainer Jeschke, Christoph Lohr, Anthony Lawrence
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Publication number: 20170247639Abstract: The present invention provides anti-fogging agents and cleaners that provide long-lasting prevention of fogging of glass, plastic, or other hard surfaces. The present invention relates to an anti-fogging agent or cleaner which contains: (A) a fluorinated amphoteric or anionic surfactant; and (B) a fluorinated nonionic surfactant. The present invention also relates to an eyeglass cleaner including a non-woven fabric impregnated with the anti-fogging agent or cleaner.Type: ApplicationFiled: September 17, 2015Publication date: August 31, 2017Inventors: Takahisa GOUDA, Yoshinao IWASAWA
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Publication number: 20170247640Abstract: This invention relates to non aqueous non-volatile alkylated siloxane compositions having low VOC and vapor pressure of about 31 millimeters of mercury at 20° C. consisting essentially of a mixture of a linear or open-chain methyl alkylated siloxane having two silicon atoms and a siloxane having three silicon atoms alkylated with methyl groups.Type: ApplicationFiled: February 25, 2016Publication date: August 31, 2017Applicant: United States of America as represented by the Secretary of the NavyInventor: El Sayad Arafat
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Publication number: 20170247641Abstract: A non-Newtonian concentrate composition includes a sensitizer or irritant, a surfactant, an anti-mist component and optionally a stability component. Example sensitizers and irritants include, but are not limited to, acids, quaternary compounds, and amines, and example anti-mist components include, but are not limited to, polyethylene oxide and polyacrylamide.Type: ApplicationFiled: May 15, 2017Publication date: August 31, 2017Inventors: Charles A. Hodge, Christopher M. McGuirk, Mark D. Levitt, Dale Larson, Elizabeth R. Kiesel, Amanda R. Blattner
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Publication number: 20170247642Abstract: Detergent compositions and methods of preparing and using the detergent compositions are disclosed. The detergent compositions comprise a polymer system comprising at least one polycarboxylic acid polymer, copolymer, or terpolymer, an alkalinity source comprising an alkali metal carbonate, a nonionic surfactant and water. The detergent compositions are suitable at alkaline pH and reduce or prevent scale formation, improve soil dispersion, and provide effective detergency.Type: ApplicationFiled: May 15, 2017Publication date: August 31, 2017Inventors: DAVID DOTZAUER, TIMOTHY MEIER, CARTER M. SILVERNAIL, JOHN MANSERGH
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Publication number: 20170247643Abstract: A cleaning agent for hard surfaces and methods for cleaning are provided herein. In one embodiment, the cleaning agent includes at least one first amylase, wherein the first amylase is an ?-amylase from Bacillus sp. No. 707 or a functional fragment or a variant thereof. The cleaning agent further includes at least one second amylase, wherein the second amylase is an AA560 ?-amylase from Bacillus sp. or a functional fragment or a variant thereof. In another embodiment, the method includes dispensing the cleaning agent into the interior of an automatic dishwasher while a dishwashing program is being executed, before the main washing cycle begins, or in the course of the main washing cycle.Type: ApplicationFiled: June 18, 2015Publication date: August 31, 2017Applicant: Henkel AG & Co. KGaAInventors: Thomas Eiting, Nina Mussmann, Thorsten Bastigkeit, Inga Kerstin Vockenroth, Noelle Wrubbel, Thomas Weber, Silke Menke
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Publication number: 20170247644Abstract: The present invention relates to novel sulfoperoxycarboxylic acid compounds, and methods for making and using them. The sulfoperoxycarboxylic compounds of the invention are storage stable, water soluble and have low to no odor. Further, the compounds of the present invention can be formed from non-petroleum based renewable materials. The compounds of the present invention can be used as antimicrobials, and bleaching agents. The compounds of the present invention are also suitable for use as coupling agents.Type: ApplicationFiled: May 11, 2017Publication date: August 31, 2017Inventors: Junzhong Li, Richard K. Staub, David D. McSherry, Keith G. Lascotte, Steven J. Lange, Frank Everts
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Publication number: 20170247645Abstract: The invention relates to fragrance mixtures comprising at least one 60 wt.-% fragrance molecules which are characterized such that they are oriented along a virtual axis X, Y and Z, having a dimension of X>5 angstrom, Y>3 angstrom and angstrom.Type: ApplicationFiled: September 4, 2015Publication date: August 31, 2017Inventors: Torsten Kulke, Sven Siegel, Patrick Ott, Anja Finke
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Publication number: 20170247646Abstract: Liquid detergent compositions can be stably structured using amides of an aliphatic polyamine with two, three or four molecules of fully saturated hydroxyl alkyl acids, even in the presence of hydrolysing detergent ingredients such as lipase enzyme.Type: ApplicationFiled: February 23, 2017Publication date: August 31, 2017Inventors: Liesbet Maria Cornelia DETROCH, Susana FERNANDEZ-PRIETO, Vincenzo GUIDA, Michael KLOSTERMANN, Hans-Jürgen KÖHLE, Bruno Jean-Pierre MATTHYS, Johan SMETS, Gonglu TIAN
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Publication number: 20170247647Abstract: A flavor nanoemulsion. The nanoemulsion contains a plurality of oil droplets, an aqueous phase, and a surfactant system including a polyethoxylated sorbitan fatty acid ester and a lecithin. Also disclosed is a liquid beverage or a liquid beverage concentrate containing the nanoemulsion and a method of preparing the same.Type: ApplicationFiled: October 20, 2015Publication date: August 31, 2017Inventors: Daniel Kaiping LEE, Chii-Fen Wang, Ying YANG, Daniel VACCARI
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Publication number: 20170247648Abstract: Autotrophic algal growth in high incident light situations may be conducted in a reactor with circulation of algal reaction medium between light and dark zones with very short residence time in the light zone to maintain algal growth in the reactor in a linear growth regime in which the rate of algal biomass production is proportional to the incident photosynthetic photon flux density. Process monitoring and control may permit quick processing in a single step even in open pond systems. Dissolved nitrogen levels in product may be monitored and nitrogen nutrient input may be restricted to reduce dissolved nitrogen in effluent and to increase lipid yield without a separate nitrogen starvation step.Type: ApplicationFiled: October 14, 2014Publication date: August 31, 2017Inventor: Alexandra D. Holland
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Publication number: 20170247649Abstract: An enzymatic processing plant for continuous flow-based enzymatic processing of organic molecules, comprises an enzymatic processing area, wherein the enzymatic processing area comprises a turbulence-generating pipe with a repeatedly changing centre-line and/or a repeatedly changing cross-section, for generating turbulence to mix a reaction mixture and prevent sedimentation of particles as the reaction mixture is flowing through the turbulence-generating pipe, and wherein the enzymatic processing plant and the enzymatic processing area are arranged such that the reaction mixture is subjected to turbulence within the enzymatic processing area for a reaction time of 15 minutes or more.Type: ApplicationFiled: September 14, 2015Publication date: August 31, 2017Inventors: Olav Asle DJUPEVÅG, Torstein FRANTZEN
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Publication number: 20170247650Abstract: The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.Type: ApplicationFiled: May 12, 2017Publication date: August 31, 2017Applicant: FULL SPECTRUM LABORATORIES LIMITEDInventors: Richard PEET, Malcolm J. KAVARANA, Robert WINNICKI, Marc DONSKY, Mingyang SUN
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Publication number: 20170247651Abstract: Bioreactors are provided that include a vessel and a jet mixer disposed in the vessel. Methods that utilize the bioreactors are provided, involving placing a microorganism or cells and a fluid medium in the bioreactor.Type: ApplicationFiled: May 11, 2017Publication date: August 31, 2017Inventors: Marshall Medoff, Thomas Craig Masterman
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Publication number: 20170247652Abstract: Devices and methods for isolating and characterizing microbial cells from an environment are provided. The devices integrate sub-micron constrictions in a nanofluidic device with a standard microtiter plate format to facilitate the high throughput isolation, culturing, analysis, and screening of bacteria and other microbial cells in natural and man-made environments, particularly environments containing microbes adhered on particulate matter.Type: ApplicationFiled: October 20, 2015Publication date: August 31, 2017Inventors: Edgar D. GOLUCH, Nil TANDOGAN
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Publication number: 20170247653Abstract: The invention relates to compositions containing Bacillus sp., optionally with magnetite, useful in methods for collecting algae. The invention also relates to methods for collecting algae by contacting algae and bare maghemite and compositions thereof.Type: ApplicationFiled: March 8, 2017Publication date: August 31, 2017Inventors: Ryan J. POWELL, Russell T. Hill
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Publication number: 20170247654Abstract: Disclosed is a method for culture of microalgae, advantageously of the genus Crypthecodinium having a gene coding for the small 18s ribosomal RNA subunit having a genetic similarity of at least 96% with the same gene of the strain of the species Crypthecodinium cohnii deposited in the CCAP (Culture Collection of Algae and Protozoa) under number CCAP 1104/3 in a defined chemical medium.Type: ApplicationFiled: August 26, 2015Publication date: August 31, 2017Inventors: Pierre CALLEJA, Cyril ROLS, Julien PAGLIARDINI, Brice BOURDENX
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Publication number: 20170247655Abstract: The present invention pertains to methods of preventing and eliminating trisulfide bonds in proteins such as antibodies. In one embodiment, trisulfide bonds in proteins are converted to disulfide bonds as part of chromatographic purification procedures. In another embodiment, the formation of trisulfide bonds in proteins is inhibited by implementation of methods described herein during the cell culture production of such proteins. In another embodiment, monoclonal antibodies are produced by the methods described herein.Type: ApplicationFiled: February 6, 2017Publication date: August 31, 2017Inventors: Rashmi Rohit KSHIRSAGAR, Alan Gilbert
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Publication number: 20170247656Abstract: Methods for using vibration to harvest cells grown in 3D culture are provided. The methods entail the application of force cells attached to a 3D matrix of sufficient amplitude, frequency, and duration to detach cells from the matrix and to flush the detached cells out of the matrix material. An apparatus for performing the methods of the invention as provided.Type: ApplicationFiled: May 15, 2017Publication date: August 31, 2017Inventors: Harel Kasuto, Nirit Drori-carmi, Barak Zohar
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Publication number: 20170247657Abstract: The present invention provides a method for generation of a cell composition of mesencephalic dopaminergic progenitor cells from a starting cell composition comprising pluripotent and/or multipotent stem cells, the method comprising the steps of a) differentiating said pluripotent and/or multipotent stem cells into mesencephalic dopaminergic progenitor cells, thereby generating a cell population comprising mesencephalic dopaminergic progenitor cells and other cells, b) dissociating the differentiated cells of step a) into a single cell suspension, and c) enriching said mesencephalic dopaminergic progenitor cells by using an antigen binding molecule specific for the CD47 antigen for positive selection of said mesencephalic dopaminergic progenitor cells in said single cell suspension. Said method may be performed in a closed cell sample processing system and may be performed in an automated manner.Type: ApplicationFiled: February 26, 2016Publication date: August 31, 2017Inventors: Andreas BOSIO, Sebastian Knobel, Daniela Lehnen, Serena Barral
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Publication number: 20170247658Abstract: A sheet-shaped cell culture is disclosed that includes myocardial cells derived from pluripotent stem cells and has excellent functional properties. A sheet-shaped cell culture obtained by culturing a cell population that includes myocardial cells derived from pluripotent stem cells, wherein the proportion of the number of the myocardial cells derived from pluripotent stem cells to the total number of cells in the cell population is 50% to 70%; a method of producing the sheet-shaped cell culture; a composition including the sheet-shaped cell culture; and a method of treating a disease using the sheet-shaped cell culture or the composition.Type: ApplicationFiled: May 12, 2017Publication date: August 31, 2017Applicants: TERUMO KABUSHIKI KAISHA, OSAKA UNIVERSITYInventors: Hiroko ISEOKA, Yoshiki SAWA, Shigeru MIYAGAWA, Satsuki FUKUSHIMA
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Publication number: 20170247659Abstract: A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.Type: ApplicationFiled: May 9, 2017Publication date: August 31, 2017Applicant: Vivex Biomedical, Inc.Inventors: Timothy Ganey, Wendy W. Weston, Miguel Quevedo, Stuart Oglesby, Gaetan Jean-Robert Delcroix, Paul C. Schiller, Gianluca D'Ippolito
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Publication number: 20170247660Abstract: The present application provides progenitor cells and a preparing method thereof. The preparing method comprises obtaining a tissue sample containing myometrium from uterus, treating the tissue sample with collagenase, and culturing the treated tissue sample to obtain the progenitor cells, wherein the progenitor cell is multipotent and immunomodulatory. The present application also provides a method for treating a degenerative disease, an ischemic disease or a disease caused by abnormal immune response comprising administering the progenitor cells to a patient subjecting the disease.Type: ApplicationFiled: September 16, 2015Publication date: August 31, 2017Applicant: National Health Research InstitutesInventors: Lin-Ju YEN, Ko-Jiunn LIU, Men-Luh YEN
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Publication number: 20170247661Abstract: A particle filtering device which shortens the separation time of particles and increases the separation efficiency are provided. The particle filtering device comprises: a filtration membrane which separates a particle by filtering a sample; a first body connected to an inlet side of the filtration membrane, which supplies the sample to the inlet side of the filtration membrane; and a second body connected to an outlet side of the filtration membrane, which accommodates a permeate whose particle is separated through the filtration membrane, wherein the particle filtering device has a structure in which the permeate is accommodated in advance between the second body and the outlet side of the filtration membrane.Type: ApplicationFiled: April 30, 2015Publication date: August 31, 2017Inventors: Yoon-Kyoung CHO, Tae-Hyeong KIM
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Publication number: 20170247662Abstract: Provided are a cancer cell-trapping metal filter which has a high opening ratio, a cancer cell-trapping metal filter sheet, a cancer cell-trapping device using the cancer cell-trapping filter, and manufacturing methods therefor. According to a cancer cell-trapping metal filter 1, openings of connected through-holes 12 that are formed in a metal sheet 11 have a wave shape, and thus it is possible to extract a CTC from other components by utilizing a hole diameter on a short-side side of the openings, and it is possible to make the connected through-holes be closer to each other due to the wave shape while maintaining a CTC trapping ability. Accordingly, it is possible to further improve the opening ratio in the cancer cell-trapping metal filter 1.Type: ApplicationFiled: March 22, 2017Publication date: August 31, 2017Inventors: Hisashige KANBARA, Yoshihito KIKUHARA, Takahiro SUZUKI
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Publication number: 20170247663Abstract: The present invention is directed generally to eukaryotic host cells comprising artificial endosymbionts and methods of introducing artificial endosymbionts into eukaryotic host cells. The invention provides artificial endosymbionts that introduce a phenotype to host cells that is maintained in daughter cells. The invention additionally provides eukaryotic host cells containing magnetotactic bacteria.Type: ApplicationFiled: May 13, 2017Publication date: August 31, 2017Applicant: Bell Biosystems, Inc.Inventors: Caleb B. Bell, III, Alexey Bazarov
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Publication number: 20170247664Abstract: Compositions and methods are provided for preparation of concentrated stock solutions of AAV virions without aggregation. Formulations for AAV preparation and storage are high ionic strength solutions (e.g. ?˜500 mM) that are nonetheless isotonic with the intended target tissue. This combination of high ionic strength and modest osmolarity is achieved using salts of high valency, such as sodium citrate. AAV stock solutions up to 6.4×1013 vg/mL are possible using the formulations of the invention, with no aggregation being observed even after ten freeze-thaw cycles. The surfactant Pluronic® F68 may be added at 0.001% to prevent losses of virions to surfaces during handling. Virion preparations can also be treated with nucleases to eliminate small nucleic acid strands on virions surfaces that exacerbate aggregation.Type: ApplicationFiled: October 6, 2016Publication date: August 31, 2017Applicant: Genzyme CorporationInventors: John Fraser WRIGHT, Guang QU
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Publication number: 20170247665Abstract: Disclosed is a novel vaccine formulation for prevention against Bluetongue virus infection in domestic and wild ruminants, cattle, goats, sheep, pigs, and any other mammals for commercial use. The antigen present in the vaccine is an inactivated antigen comprising 5 different serotypes of Bluetongue virus, thereby making a pentavalent vaccine formulation against Bluetongue virus infections. Also disclosed are method of adaptation of Bluetongue virus in suspension culture upto 2000 liters industrial size bioreactors, and inactivation techniques for preparation of the given vaccine formulation with the presence of suitable adjuvants and preservatives.Type: ApplicationFiled: August 21, 2015Publication date: August 31, 2017Inventors: Tapas BHATTACHARYA, Shree Naravan SINGH