Abstract: Meniscal repair devices, systems, and methods are provided.

Abstract: Embodiments of the invention describe methods of implanting and setting an adjustable suture structure capable of maximizing and controlling the available range of motion in a defective joint. The adjustable suture structure can augment a joint repair following surgery or be used as a standalone construct. One embodiment involves completion of a standard ligament repair, followed by the implant of anchors to secure sutures between bone locations proximal to the native origin of the repaired ligaments. Each of the sutures is implanted with at least some slack. Once the sutures are secured, the first suture is alternatively tensioned and moved through a range of motion, followed by the same process in a second suture. The steps are performed iteratively until the range of motion is controlled or limited sufficiently to protect the repaired ligaments.

Abstract: An article of manufacture in the form of an incursion repair material arranged to establish a watertight seal about an incursion such as a durotomy and secured in place by a securing mechanism. The incursion material may be graft material and/or a flange of selectable shape and size and made of a material suitable to remain in position on the incursion. The incursion repair material is used in a surgical procedure to seal the incursion. The material may be secured in place with one or more sutures only. It may also be secured in place with devices anchored in underlying substrate, such as bone or scar tissue.

Abstract: An illustrative example suture securing assembly includes an inserter, a rigid member and a second member. The inserter includes a distal end, a proximal end, and a longitudinal axis between the distal end and the proximal end. The inserter includes a handle near the proximal end and a rotatable portion near the handle. The rigid member includes an eyelet oriented to thread suture across the longitudinal axis. The rigid member is situated near the distal end of the inserter. The rigid member is configured to be placed in bone. The second member is situated near the distal end of the inserter and is configured to be rotated by the rotatable portion of the inserter to rotationally advance the second member in a distal direction toward the eyelet into a suture securing position where the second member holds suture in place.

Abstract: Surgical constructs and methods are provided for securing soft tissue to bone. One exemplary embodiment of a construct is formed from a suture filament and includes two terminal ends of filament and an intermediate portion disposed along at least a portion of a length extending between the terminal ends. The construct can have a first terminal end that is the first terminal end of the filament, and a second terminal end that includes a loop. The loop can be formed by disposing the second terminal end of the filament within a volume of a portion of the intermediate portion of the filament. In some disclosed methods, both terminal ends of the filament can be passed through tissue when performing soft tissue repairs. Various other embodiments of constructs and methods are provided, including constructs having two or more filaments associated with an anchor and methods of using such constructs.

Abstract: Meniscal repair devices, systems, and methods are provided.

Abstract: Suturing devices and systems used to close openings into a biological structure. The suturing device can comprise an elongate member having a proximal end, a distal end, one or more arms, and one or more needles. One or more sheaths may be used with the device to maintain or substantially maintain haemostasis while the device is used and while a procedure is performed in the biological structure.

Abstract: A knot for suturing includes a temporary knot for suturing a wound, in which the temporary knot has a first loop extending form a start part and wound clockwise, a ring part extending from the first loop and formed at different position from the first loop, a second loop extending from the ring part and wound counterclockwise at the same position as the first loop, and a spare part extending from the second loop to be pulled by a suturing needle. A suturing device includes a suturing needle formed in a hook shape at a front end of a suturing body formed in a plate shape to pierce a wound and a knot supply unit disposed on the suturing body and holding and supplying knots for suturing toward the suturing needle so that the suturing needle stitches the wound.

Abstract: Shape memory tissue engagement elements (15) are created using shape memory alloys or shape memory (SM) composite sheets (33, 36) with one or more SM material sheets (20, 32). Arrays of the tissue engagement elements may then be inserted or molded into flexible base materials forming pads for tissue engagement. In certain embodiments, the composite sheets incorporate two SM material layers (20, 32) having differing transition temperatures to allow activation of one layer for tissue engagement and activation of the second layer for tissue release. In exemplary embodiments, insertion of interconnected tissue engagement elements (46) into a base layer (19) with slots (48) provides a completed pad array. In alternative exemplary embodiments, vacuum forming of composite sheets (51) with cutting of corrugated sides (53) to form tissue engagement elements allow production of complete arrays of tissue engagement elements. Overmolding the arrays with a flexible base material (19) provides a completed pad.

Abstract: Disclosed herein is a needle for being connected to a suture, including: a body having a tip portion disposed at one end portion thereof and a rear end portion disposed at the other end portion thereof; and a suture connection part formed in a side surface portion of the body, wherein the suture connection part includes a reception path extended toward a lengthwise axial portion of the body and receiving a portion of the suture therein, and a closure member constituting a portion of the body and deformed by external force after a portion of the suture is received in the reception path, thereby closing a portion of the reception path.

Abstract: A mounting member for a surgical stapler is fabricated from a plastic. The mounting member has a proximal end portion and a distal end portion. The proximal end portion has a pair of vertical projections configured to be coupled to a proximal body portion of a loading unit of a surgical stapler. The distal end portion includes a pair of walls extending distally from the proximal end portion. Each wall has a boss and a strut. The boss defines a transverse bore therethrough configured to be rotatably coupled to a cartridge assembly of the loading unit. The strut extends from the proximal end portion to the boss.

Abstract: A mechanical system for bilaterally securing skin tissue preferably utilizes a tissue manipulator apparatus to approximate a portion of an interior surface of each of two pieces of living dermis tissue along a vertical interface below an exterior surface without overlapping either interior surface across the vertical interface. An applicator apparatus includes a driving head portion positioned in the vertical interface and at least partially below the exterior surface and a handle portion positioned at least partially above the exterior surface. The applicator apparatus bilaterally drives at least one portion of the fastener through each piece of the living dermis tissue behind the interior surface of that piece of tissue such that the fastener is positioned below the exterior surface and a portion of the fastener is positioned generally transverse to the vertical interface.

Abstract: A laparoscopic clip applier can have a geared clip feed mechanism and a direct jaw clamping mechanism to provide smooth operation over a clip application stroke of a movable handle. The geared clip feed mechanism can include an idler gear and two drive gear racks to advance a feed slider feeding a clip to a jaw assembly. The two drive gear racks can be positioned to provide different gearing during clip feed and firing portions of the clip application stroke, allowing efficient packaging of the clip feed mechanism. A spring can rapidly withdraw the feed slider once the clip has been fed and before clamping begins. The movable handle can have a direct connection to a clamping slider to enhance user feedback during clamping of the clip. After clamping the clip, the movable handle can also assist in returning the clamping slider to an initial position for firing another clip.

Abstract: Systems and methods introduce and prosthesis into a blood vessel or hollow body organ by intra-vascular access. The prosthesis is secured in place by fasteners which are implanted by an applier that is also deployed by intra-vascular access. The applier is configured to permit controlled, selective release of the fastener in a step that is independent of the step of implantation.

Abstract: An apparatus includes a body assembly, a shaft extending distally from the body assembly, an end effector attached to the shaft, and a cartridge. The end effector includes a jaw and an anvil pivotable relative to the jaw. The cartridge includes a deck, a plurality of staples, a compressible buttress, a peripheral member, and a pinching surface. The deck has an upper surface facing toward the anvil. The staples are located within openings formed through the deck. Each staple has a pair of legs extending above the upper surface of the deck. The buttress is located on the upper surface of the deck. Portions of the legs of the staples are disposed the buttress. The peripheral member extends above the upper surface of the deck, laterally adjacent to the buttress. The pinching surface is located at a height extending above a height of the legs of the plurality of staples.

Abstract: A surgical instrument includes a body assembly, a shaft assembly, and an end effector. The end effector has first and second jaws that are configured to receive a tissue therebetween. The end effector also includes a staple cartridge including a plurality of staples and a hydraulic expandable member that is configured to receive a fluid and thereby expand from a contracted state to an expanded state. The hydraulic expandable member is further configured to direct at least one of the plurality of staples toward an anvil of the first jaw for forcing the at least one of the staples against the anvil and forming the at least one of the staples within the tissue.

Abstract: A surgical instrument includes a body, a shaft assembly, and an end effector. The end effector a first jaw, a second jaw, and a staple cartridge. The first jaw has an anvil that is configured to form a plurality of staples. The first jaw is movable relative to the second jaw from an open configuration toward a closed configuration for capturing the tissue therebetween and forming the staples therein. The staple cartridge includes a plurality of staples, a body, and a deck. The body is received by the second jaw. The deck has a plurality of staple pockets such that the plurality of staples are configured to pass through staple pockets. The deck is configured to selectively move relative to the body from a first position to a second position for adjusting a height of the deck relative to the anvil while the body is received in the second jaw.

Abstract: An apparatus includes a body assembly, a shaft, an end effector, and a cartridge. The end effector includes a jaw, a pivotable anvil, and a knife member. The cartridge includes a deck, a buttress assembly, and a folding sled. A first portion of the buttress assembly is positioned on top of the deck. A second portion of the buttress assembly is positioned within the longitudinal channel. The folding sled is configured to translate within the longitudinal channel to move the second portion of the buttress assembly to a position that is above the deck in response to actuation of the knife member. The second portion of the buttress assembly is thereby secured against edges of tissue severed by the knife member.

Abstract: A device includes a first end portion, a second end portion, an intermediate portion, and a graft material. The first end portion has a first end diameter. The second end portion has a second end diameter smaller than the first end diameter. The first end portion comprises a first material. The second end portion comprises a second material different than the first material. The intermediate portion is between the first end portion and the second end portion. The intermediate portion tapers between the first end portion and the second end portion. The graft material is coupled to at least the intermediate portion.

Abstract: The invention relates to a perivascular ring having an inner diameter adjustable by inflation/deflation and adapted to be implanted and closed about a vessel for controlling the inner diameter of said vessel and thus the flow and/or pressure of a fluid flowing in said vessel. The ring of the invention is capable of regulating blood flow to the liver, in particular after an hepatectomy or hepatic transplant, and to substantially improve the survival chances of the patient. The ring according the invention has an adjustable inner diameter (Øi) for implantation and locking about a vessel.

Abstract: A surgical clip device is provided for closing vessels, for example in neurosurgery. The surgical clip device is provided with at least two electrically conductive clip parts that are electrically isolated from each other and are arranged at a predetermined distance opposite each other. Each of the two clip parts may be held with a first free end thereof on an electrically isolating holding part in one of a U-shaped or a V-shaped configuration.

Abstract: Provided herein is a mechanical device including a rotating spool assembly and a disposable valve assembly. The rotating spool assembly includes a hub, an arm, and a spool inserted through an opening in the arm. The rotating spool assembly can be sterilized after each use. The disposable valve assembly includes a mating stem member, a sealing member, and a flushing port member. The disposable valve assembly can be disposed of after every use. A loading member is also provided including a wire that can be formed from metal drawn out into a thin flexible thread. The loading member can be pre-formed in a helix to form coils in the wire. A release cord is provided including a braided cord with two single filaments and a plurality of beads formed along a length of the single filaments at a distal end of the braided cord.

Abstract: A vasculature occlusion device detachment system including a wound coil heating element of a predetermined resistivity. A coil securing suture terminates in a proximal bead retained within the wound coil heating element while the distal end of the coil securing suture extends beyond the distal end of the wound coil heating element and is attached to the proximal end of the vasculature occlusion device. The coil securing suture is independently rotatable of the wound coil heating element 360 degrees about a longitudinal axis extending therethrough the wound coil heating element. A power source applies electrical current to the wound coil heating element via an electrically conductive corewire and separate insulated electrically conductive wire to increase its resistance and, as a result of the heat produced, sever the coil securing suture.

Abstract: An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert.

Abstract: Provided is a cutting instrument including: an elongated member including a tubular portion 105 and a shaft-like portion 101 inserted m the tubular portion 105; a blade 201 including two edges, the blade 201 being provided at an end of the elongated member and being pivotable between a housed position and a projected position; and a motion mechanism that converts a relative movement of the tubular portion 105 and the shaft-like portion 101 resulting from an operation of an operation portion 102 to 104 into pivoting of the blade between the housed position and the projected position, wherein the cutting instrument moves toward the operation portion while rotating in its entirety with the two edges of the blade 201 projected on opposite sides of the tubular portion 105, thereby drilling a hole with a diameter larger than an outer diameter of the tubular portion 105.

Abstract: Embodiments of apparatuses and methods for microfracture (e.g., forming a plurality of microfractures in a bone to encourage cartilage regeneration).

Abstract: A surgical method and tool for expanding an initial osteotomy (42) to receive a bone implant (44). An osteotome (22) having a tapered working end (28) is inserted into the initial osteotomy (42). The initial osteotomy (42) is enlarged by simultaneously rotating and pushing the working end (28) of the tapered osteotome (22) into the osteotomy (42). When rotated in one direction the burnishing edges (40) concentrate the pushing and rotational force in outward normal and tangential component forces against the interior surface of the osteotomy (42) to incrementally expand the osteotomy (42) with little to no removal of bone material (46). When rotated in the opposite direction the burnishing edges cut the interior surface of the osteotomy. Progressively larger tapered osteotomes (22) are used until an osteotomy (42) of predetermined size is achieved.

Abstract: An orthopaedic reamer connector includes a holder section shaped to allow for connection of an orthopaedic reamer, the holder section including a connection surface and two pairs of holders associated with the connection surface, each of the two pairs of holders having a first holder and a second holder that forms an acute angle relative to the first holder, the first holders being opposed to each other by about 180 degrees and the second holders being opposed to each other by about 180 degrees; and a stop section mechanically interlocked with the holder section so as to prevent relative rotation therebetween and including a pair of stops associated with each of the two pairs of holders, each of the pair of stops having a first stop associated with the first holder and a second stop associated with the second holder.

Abstract: A cleaning module for cleaning bone stock used in surgical procedures. The cleaning module includes a shell. The shell defines a void space to receive the bone stock. A cutter is rotating mounted in the void space. A shaving tube, also able to rotate, is coaxially disposed about the cutter. The cutter and shaving tube have complementary edges. A drive assembly rotates the cutter and shaving tube at different speeds, at different times or in different directions relative to the cutter. As a result of the rotation of the cutter and shaving tube soft tissue adhering to the bone stock is cut away from the bone stock by the relative rotating of the cutting edges of the cutter and shaving tube.

Abstract: Systems and methods for joint preparation and fusion are disclosed. The system includes a cutting device having a handle, and rigid blade member. The blade member may include cutting edges on first and second sides, and may be curved in one or more planes. The blade member may be deployed to project outside of an outer tube, and the cutting device may be rotated to create a circular cavity. In a method of use, a cannula provides access to a procedure site such as a joint. A pathway to the joint is created, and the cutting device is inserted and deployed to undercut a cavity in the joint. A fusion device may be implanted across the joint to provide compression and fuse the joint. The system may also include instrumentation for creating access to a joint, bone graft insertion and implant insertion.

Abstract: Mechanical thrombectomy apparatuses (devices, systems, etc.) and methods for positioning them within a vessel and using them to remove a thrombus, e.g., clot, from within a vessel. In particular, described herein are methods of advancing an inverting tractor thrombectomy apparatus having a tractor comprising a flexible tube of material that inverts over itself as it rolls over a distal end opening of an elongate inversion support by extending the tractor region and/or a puller coupled to the tractor distally beyond the end of the catheter. Also described herein are power-driven mechanical thrombectomy apparatuses.

Abstract: A percutaneous nephrolithotomy (PCNL) needle may include a cannula including a shaft and a cannula hub coupled to a proximal end of the cannula shaft. A depth guide may be disposed on an outer surface of the cannula shaft. A stylet may be disposable within the cannula lumen and may include a tapered point at a distal end of the stylet and a stylet hub coupled to a proximal end of the stylet that is configured to be releasably securable to the cannula hub. An adjustable depth stop may be releasably securable to the cannula shaft at a desired position relative to the depth guide, the adjustable depth guide capable of being manipulated between an adjustment configuration in which the adjustable depth guide is moveable relative to the cannula shaft and a secured configuration in which the adjustable depth guide is secured relative to the cannula shaft.

Abstract: In accordance with some configurations, systems and methods for guided removal from an in vivo subject are provided. In some configurations, a method for removing an object is provided. The method comprising, guiding a flexible tube through an in vivo subject's ureter, wherein the flexible tube comprises at least a first passageway and a second passageway. Positioning a distal end of the first passageway adjacent to the object. Infusing saline solution through the second passageway while suction is off. Removing the object through the first passageway with at least a portion of the saline solution.

Abstract: Mechanical thrombectomy apparatuses including an inverting, rolling conveyor region (“tractor”) at the distal end that are configured to grab and remove thrombus material. In particular, described herein are mechanical thrombectomy apparatuses that are adapted to prevent premature deployment of the tractor, e.g., by including a tractor hold (e.g., a housing, a lock, a clamp, etc.) or the like to secure the outer end of the tractor against and/or relative to the elongate inversion support.

Abstract: The present invention relates to an extraction device (10) for extracting foreign bodies from a patient, comprising a flexible extractor (11), a stiffening device (12) and connection means (13) for connecting the flexible extractor (11) to said stiffening device (12).

Abstract: Devices including, but not limited to, a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member.

Abstract: A stone retrieval device includes a sheath and a stone retrieval basket that includes a distal region with a plurality of basket wires and a proximal region with one or more core wires. The stone retrieval basket is contained within the sheath and is movable out a distal opening of the sheath to cause the plurality of basket wires to open into a basket shape. The stone retrieval device further includes a lock mechanism that locks the position of the stone retrieval basket with respect to the position of the sheath and a basket force controller that includes a first and a second control stage. The first control stage includes a sensor for measuring force on the stone retrieval basket when the lock mechanism is in an unlocked position, and the second control stage includes a sensor for measuring force when the lock mechanism is in a locked position.

Abstract: Described here are devices and methods for forming shock waves. The devices may comprise an axially extending elongate member. A first electrode pair may comprise a first electrode and a second electrode. The first electrode pair may be provided on the elongate member and positioned within a conductive fluid. A controller may be coupled to the first electrode pair. The controller may be configured to deliver a series of individual pulses to the first electrode pair, where each pulse creates a shock wave. The controller may cause current to flow through the electrode pair in a first direction for some of the pulses in the series and in a second direction opposite the first direction for the remaining pulses in the series.

Abstract: Mechanical thrombectomy systems including an elongate catheter configured as an elongate inversion support, a flexible tractor configured to roll and invert over the distal end of the elongate inversion support, and a clot engaging member on the distal end of an elongate manipulator are described herein. These systems may capture a clot using the clot engaging member and draw the clot and clot engaging member and roll the flexible tractor into the catheter to remove the clot and clot engaging member from a vessel.

Abstract: Mechanical thrombectomy apparatuses that may be configured to prevent or reduce jamming (e.g., “anti-jamming” thrombectomy devices), grab clot, and/or macerate the thrombus, e.g., clot, being removed. These mechanical thrombectomy apparatuses may include a tractor comprising a flexible tube of material that inverts as it rolls over itself while being drawn into a catheter in a conveyor-like motion. In particular, described herein are mechanical thrombectomy apparatuses having tractors selectably extendable projections that may aid in grabbing and/or macerating a clot. Also described herein are seesawing tractors for mechanical thrombectomy apparatuses.

Abstract: A thrombectomy device including a delivery catheter; a tapered dilator catheter configured to be movably disposed within the delivery catheter; and an expandable aspiration funnel configured to be movably disposed within the delivery catheter in a retracted position and at least partially outside the delivery catheter in an extended position, the funnel comprising a non-permeable covering, a diameter of a distal end of the funnel being greater in the extended position than in the retracted position, the funnel being configured to adapt its shape and length to a surrounding blood vessel such that the funnel lengthens as it narrows to retain a thrombus within the funnel. The invention also includes methods of using the device.

Abstract: A surgical instrument includes a housing and an elongated shaft extending distally therefrom. The elongated shaft includes a proximal portion, a distal portion and a flexible portion supported therebetween. The flexible portion permits pivotal movement of the distal portion of the elongated shaft and an end effector supported thereon. A locking mechanism is operatively associated with the flexible portion of the elongated shaft to selectively impede pivotal motion of the distal portion. The locking mechanism includes a locking coil disposed about an axis defined by the flexible portion of the elongated shaft. A distal end of the locking coil is coupled to the distal portion of the elongated shaft, and a proximal end of the locking coil is rotatable about the longitudinal axis to laterally approximate the locking coil to flexible portion, and thus frictionally engage the flexible portion of the elongated shaft to selectively impede articulating motion thereof.

Abstract: Disclosed is a four-jawed combinational scissor-grasper surgical tool for use in laparoscopy, Cutting and grasping functionalities are respectively enabled via movement of a pair of such specially contoured jaw members sliding against or splaying apart from the other pair. Also disclosed are means for achieving selectable interlocking of jaw members and mechanical linkage for their actuation by human user.

Abstract: The present invention is directed to surgical staplers stapling and resecting tissue comprising a surgical buttress at least partially disposed on a tissue facing surface of at least one of the cartridge or the anvil, said buttress having width substantially larger than width of said tissue facing surfaces; said buttress comprising a first portion positioned over the deployable staples or over the staple forming pockets, and at least one flap portion not positioned over the deployable staples or over the staple forming pockets; said flap portion folded or rolled on itself and configured to be unfurlable and wrappable about the resected tissue. The present invention is also directed to methods of use of such stapler assembly devices.

Abstract: This disclosure relates to surgical instruments with selectively rotating handles. In certain aspects, the surgical device includes a conduit having a longitudinal axis and configured to extend into a body lumen, and a handle coupled to the conduit and configured to selectively rotate relative to the conduit. The handle is coupled to the conduit by a connection including a clutch mechanism, and the handle is configured to rotate in response to a user activation of the clutch mechanism.

Abstract: A pair of endoscopic scissors includes a pair of scissor pieces facing and overlapping, the scissor pieces being pivotally supported by a turning pivot extending in overlapping direction such that the pair is opened and closed and having cutting portions that grips and incises biological tissue, and an operation wire that applies driving force to base end portion sides of the scissor pieces such that opening-closing operation of tip end portions of the scissor pieces is performed. One or more scissor pieces have a tip end portion having a claw that grips the tissue and is protruding in closing direction beyond respective cutting portion, a concave penetrating the respective cutting portion in thickness direction is locally formed in the respective cutting portion, and the respective cutting portion excluding the claw and concave is formed to have a flat and linear shape extending in tip end-base end direction.

Abstract: A treatment instrument which is used under an environment filled with an electrically conductive liquid, the treatment instrument includes: a probe comprising a treatment portion which treats a treatment target part by ultrasonic vibration, and a back portion provided on a side opposite to the treatment portion, the probe constituting one pole in a bipolar treatment; a hollow sheath which comprises a protrusion to constitute the other pole in the bipolar treatment and which surrounds the probe; and a cutout which is provided in the sheath to expose the treatment portion of the probe and which comprises portions different from each other in inclination to a central axis of the probe.

Abstract: A cannula and needle assembly configured to first have the needle assembly create an opening in the skin of a person or animal and to then insert the cannula through the needle into the person or animal by way of the opening created by the needle. The assembly also includes structure to yieldably maintain the needle assembly in a docked position.

Abstract: The invention relates to a system for controlling with respect to a body of a patient, displacement of an intervention device having an end intended to be inserted in the body of the patient through a point of penetration, comprising: A base (10) intended to be in a fixed position relative to the patient; A first portion (20) comprising an arc member (21), said first portion (20) being pivotally mounted on the base (10) around a first axis (A1), wherein said first axis (A1) is parallel to an arc plane defined by the arc member (21); A second portion (30) comprising a support member (32) and a carrier member (31), said support member (32) having a longitudinal axis and said carrier member (31) being slidably mounted on the arc member (21) for partially rotating around a second axis (A2), said second axis (A2) extending through a centre of curvature of the arc member perpendicularly to the arc plane, wherein the second axis (A2) and the first axis (A1) are perpendicular; A third portion (40) comprising a ho

Abstract: The present invention discloses a self-sealing cannula and methods of its use. The self-sealing cannula can be minimally invasively placed into the heart for drawing and/or returning blood with a self-sealing function at the interface of the blood access site. The disclosed cannula can be implemented as a single lumen cannula or a double lumen cannula, which can be used with ventricular assist devices for heart support or pump-oxygenators for ECMO and respiratory support. Through a self-sealing mechanism fixed on the ventricular wall or atrial wall, a cannula body is attached to the self-sealing fixture and blood is drawn into the lumen via an external pump and returned to the circulation system through a separate cannula. In the case of the double lumen cannula embodiment, the blood will be drawn into the drainage lumen of the double lumen cannula and returned through an infusion lumen at the desired location.