Abstract: The present invention regards an applicator device for the preparation and application of at least one medical substance, preferably a coloured liquid, comprising: a hollow chamber having a hosting end and an opposite distal end in communication with means for contact with the patient; a cartridge slidingly inserted into said hollow chamber, containing at least one first medical substance, and having a first end external to the hollow chamber, and a second end completely inserted into the hollow chamber; a breaking means positioned at the distal end, capable of establishing a fluid communication between the internal of the cartridge and the means for contact with the patient; said second end being sealed by a filled double layer closure system containing at least one second substance, preferably coloured, mixable and/or soluble with the first medical substance contained in the cartridge.

Abstract: A ported catheter adapter having a combined blood control valve and port valve, wherein the combined valve comprises one or more vents that permit the passage of air and prevent the passage of fluids. The one or more vents are located on the outer surface of the valve so as to avoid being overlapped with the pathway of the side port. As such, fluid communication between the side port and the vents is prevented. Various venting configurations are provided. The invention further includes a valve actuator that is advanced through a slit in the membrane of the valve to provide a pathway for fluid to bypass the valve.

Abstract: A fitting assembly includes a fitting and a tube. The fitting has a fitting body having a straight through hole and an attachment or base port, connected to the through hole by a first passageway generally perpendicular to the through hole. The tube has an outer diameter smaller than the through hole allowing a first end of the tube to pass through the through hole. A seal is positioned in one of a circumferential slot in the tube and a circumferential slot in the through hole of the fitting body, the seal sealing a second end of the tube to the fitting body. A cover is sealingly attached to the first end of the through hole. One of the cover and the tube has a portion that extends into an intersection of the through hole and the first passageway, the portion having an aperture that prevents blockage between the attachment or base port and the second end of the through hole.

Abstract: An electroceutical apparatus and self-care method for treating pain by providing Transcutaneous Electrical Nerve Stimulation (TENS) in combination with pulsed Ultrasound or Light Emitting Diode (LED) treatments. In some embodiments, the apparatus includes a pod unit and a controller, and wrap for holding the pod unit on an area of a user's body. In some embodiments, the wrap may include electrodes and the intensity of the TENS treatment may be adjusted by a user via the controller. In some embodiments, the frequency or output of the treatments is fixed and sequentially delivered to the user in a timed manner.

Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.

Abstract: An electrical stimulation lead includes at least one lead body having a distal end portion, a proximal end portion, and a longitudinal length. The lead further includes a paddle body extending from the distal end portion of the at least one lead body, electrodes disposed along the paddle body, terminals disposed along the proximal end portion of the at least one lead body, and conductors electrically coupling the terminals to the electrodes. The lead further includes an anchoring device threadably disposed in at least a portion of the paddle body. The anchoring device has a head element and a tissue-engagement element fixed to the head element such that actuation of the head element urges the tissue-engagement element away from or toward the paddle body.

Abstract: An implantable neural tissue electrode assembly includes a cylindrical electrode lead with at least one electrode contact on the outer surface of the electrode lead. An active distal end fixation anchor is located at the distal end of the electrode lead and is adapted to fasten to adjacent tissue by rotation in a fastening direction. A passive rear fixation anchor is located on the outer surface of the electrode lead offset a longitudinal distance back from the distal end and has at least one curved blade with a blade tip directed away from rotation in the fastening direction. The rear fixation anchor is adapted to permanently fasten to adjacent tissue by rotation opposite to the fastening direction so that the blade tip cuts into the adjacent tissue, and the electrode assembly is adapted such that physiological induced strains are distributed along the electrode lead.

Abstract: An implantable electrical stimulating device and system provides for a remote determination of the identity of the person in whom the stimulating device is implanted. The stimulating device may be a pacemaker, a defibrillator, another medical device or a non-medical device. The bases for the remote identification are (1) the commingling of (A) biologic identification information of the person linked to the stimulating device, and (B) information pertaining to a physiologic parameter (e.g. heart rate information) of that person, and (2) the modulation of the physiologic parameter by external information. Embodiments of the invention in which the stimulating device is external to the person are possible. By utilizing the apparatus providing for the remote identification of a person plus stimulating device, one aspect of secure communication—that based on reliable mutual identification of each participant in a communication—is achieved.

Abstract: A ratio of reversible electroporation and irreversible electroporation may be controlled by selecting a symmetric waveform or asymmetric waveform to either minimize or enhance irreversible effects on cells in the target tissue. Combined reversible and irreversible electroporation includes inserting one or more therapeutic electrodes into a target tissue, introducing an electroporation compound into the target tissue, selecting a pulse waveform that is either 1) asymmetric bipolar that has positive and negative pulses with different durations, or 2) symmetric bipolar that has positive and negative pulses with the same duration, and delivering to the target tissue a series of electrical pulses having the selected pulse waveform.

Abstract: A method of treating a waste evacuation dysfunction comprising administering transcutaneous electrical stimulation (TES) to at least one lower pelvic and/or sacral region for a specific treatment regimen. Also disclosed is a system for configuring a stimulation device to deliver transcutaneous electrical stimulation (TES) the system comprising: a computing device storing or having access to a plurality of TES settings and comprising a user interface to enable authorized selection of at least one of the TES settings for provision of TES by the stimulation device according to the at least one selected TES setting and the stimulation device communicatively coupled to the computing device to receive and store the selected at least one TES setting the stimulation device being of a size to be readily carried on a body and configured to selectively provide current to external electrode according to the one TES setting.

Abstract: This Abstract describes a method to restore and/or improve the libido, the sex drive, in males and females, without introducing any external unnatural drugs. The process utilizes a TENS/EMS (Transcutaneous Electrical Nerve Stimulation/Electronic Muscle Stimulation) machine to naturally generate the increased production by the human body's nerve fiber's neurotransmitters. Neurotransmitters that help the Libido include Serotonin, beta-Endorphin, Cortisol, Adrenocorticotropic hormone (ACTH), gamma-Aminobutyric acid (GABA), and Dehydroepiandrosterone (DHEA). This leads to the production of higher levels of estrogen, testosterone, or progesterone. The method requires a TENS/EMS power source, two electrodes, wiring, and optionally two additional electrodes. TENS/EMS units have no side effects other than possible skin irritation (where the electrodes are placed on the skin; if the machine is left on too long).

Abstract: Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber. The system may sense a physiological signal including during electrostimulation of the heart, use the physiological signal to determine a first stimulation vector for electrostimulation at a first left ventricular (LV) site and a second stimulation vector for electrostimulation at a different second LV site, and determine a therapy mode including a first chronological order and a first timing offset between stimulations delivered according to the first and second stimulation vectors. The electrostimulation circuit may deliver electrostimulation to the heart in accordance with the first and second stimulation vectors and the therapy mode.

Abstract: Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure. The method may include positioning an expandable balloon in a renal artery of the patient. The expandable balloon may include a plurality of electrode assemblies. At least some of the electrode assemblies each may include at least two bipolar electrode pairs. The two bipolar electrode pairs may be longitudinally and circumferentially offset from one another. The method may also include expanding the balloon in the renal artery such that at least some of the bipolar electrode pairs are electrically coupled to a wall of the renal artery and energizing at least some of the bipolar electrode pairs so as to therapeutically alter at least one nerve proximate the renal artery to treat the patient's congestive heart failure.

Abstract: A neuromodulation system executes a set of startup operations. In response to completion of the startup operations, a priming field is automatically initiated. The priming field is to produce a priming effect in priming-targeted neural tissue, with the priming effect causing a change in sensitization to a therapeutic neuromodulation field of the priming-targeted neural tissue. The system also generates the therapeutic neuromodulation field to produce a therapeutic effect in therapy-targeted neural tissue.

Abstract: Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.

Abstract: An example of a system may include electrodes on at least one lead configured to be operationally positioned for use in modulating neural tissue where the neural tissue including dorsal horn tissue or nerve root tissue, a neural modulation generator, and a controller. The neural modulation generator may be configured to use at least some electrodes to generate a modulation field. The neural modulation generator maybe configured to use a programmed modulation parameter set to promote uniformity of the modulation field in the dorsal horn tissue. The controller may be configured to control the neural modulation generator to generate the modulation field in pulse trains of at least two pulses.

Abstract: A telemetry port for providing an open space in which an antenna may transmit and receive signals free from interference from the metal shell of an implantable medical device, the telemetry port includes a housing defining a void space for receiving an antenna. The void space is configured to provide the antenna with sufficient space such that the antenna does not contact the housing. The housing further includes a periphery positioned along a bottom edge capable of being integrated to an implantable medical device, and forming a hermetic seal with the implantable medical device.

Abstract: An implantable device has a cylindrical base, at least one electrode on the cylindrical base, at least one electrically conducting lead on the cylindrical base connected to the electrode wherein the electrically conducting lead has a feature size of <10 micrometers. A protective coating on the cylindrical base covers the at least one electrically conducting lead.

Abstract: A neuromodulation device is configured with a set of testing program configuration instructions including therapeutic neuromodulation field-setting parameters. The device determines a custom priming program in response to the testing program configuration instructions. The custom priming program controls the neuromodulation device to generate a priming field with specific correspondence to the therapeutic neuromodulation field to be produced by the testing program.

Abstract: Provided embodiments include a device, apparatus, system, computer program product, and method. A medical apparatus is provided. At least a portion of which is configured for implantation in an animal. The medical apparatus includes a communication module configured to receive communications originating external to the animal. The medical apparatus also includes a threat assessment module configured to ascertain a threat characteristic of a communication received by the communication module. The medical apparatus further includes a threat mitigation module configured to implement a mitigation measure responsive to the ascertained threat characteristic of the received communication.

Abstract: A system may include a processor configured to automatically obtain magnetic resonance imaging compatibility information relating to compatibility of an active implantable medical device implantable in a patient with an MRI modality from at least two information sources. The processor may also be configured to automatically determine compatibility of the active implantable medical device with the magnetic resonance imaging modality based on the magnetic resonance imaging compatibility information.

Abstract: In an aspect, a system for treating a patient in cardiac arrest is described and includes memory, one or more electronic ports for receiving signals from sensors for obtaining indications of an electrocardiogram (ECG) of the patient, one or more sensors for obtaining a transthoracic impedance of the patient, and a patient treatment module executable on one or more processing devices that is configured to generate, from the ECG, transform values that represent magnitudes of two or more frequency components of the ECG, and modify, based on at least one transform value, at least one shock delivery parameter.

Abstract: A method of soft tissue treatment of a patient includes placing an applicator onto a surface of the soft tissue, with the applicator including an electrode and a dielectric material vacuum cup. The soft tissue is heated via the electrode. Vacuum is applied to the vacuum cup. The electrode may be at least partially covered by a dielectric material of variable thickness.

Abstract: A neuromodulation device generates a therapeutic neuromodulation field to produce a therapeutic effect in therapy-targeted neural tissue, and a priming field to produce a priming effect in priming-targeted neural tissue. The priming effect causes a change in sensitization of the priming-targeted neural tissue to the therapeutic neuromodulation field. The priming field is generated concurrently during generation of the therapeutic neuromodulation field to increase efficacy of the therapeutic effect.

Abstract: A portable light therapy treatment assembly includes a housing and a control unit that is mounted in the housing. A power supply is mounted in the housing and electrically coupled to the control unit. A light emitter is mounted in the housing and emits light outwardly of the first end when the light emitter is turned on. The light emitter is electrically coupled to the control unit. The control unit is programmed to allow the light emitter to be used a pre-selected number of usages. Each of the usages defines a treatment and the total number of usages defines a prescription. The control unit requires a reset input when the prescription has been fully utilized.

Abstract: System for treatment by photodynamic therapy comprising: —an illuminating device (10) including a light emitting surface for illuminating an internal surface to be treated with a light adapted to activate a photosensitizer compound, the light emitting surface emitting light with a distribution of light power comprising fractions of light power decreasing from a maximum at the light emitting surface, the light emitting surface having a determined illumination profile that provides respective illuminated areas for a plurality of the fractions of light power, —a positioning system (40) adapted to position in real-time the light emitting surface within a reference frame, —an electronic unit (45) connected to the positioning system (40) and adapted to monitor in real-time a dose of light energy delivered to the internal surface based on the illumination profile and the position of the light emitting surface.

Abstract: The present invention relates to a therapy system for the treatment of the skin and subdermis with light. The system comprises a NIR light source which produces light with a wavelength adapted to an absorption maximum for exciting molecular oxygen in aqueous solution; an image recognition unit for detecting papillary end arterioles and their x-y-z coordinates, wherein a respective depth underneath the skin surface is determined as the z-coordinate by an autofocus function; an optical system for the optical coupling of the light of the NIR light source and the pattern recognition unit to the skin, with a focussing unit to controllably position the light with at least one focus point in the skin; and a control unit to control the NIR light source, the image recognition unit, and the optical system.

Abstract: The present disclosure is concerned with a skin treatment device having at least a first LED, at least a first controllable current source, in particular a first controllable constant current source, for driving the first LED, a control unit for controlled switching of at least the first controllable current source between a first state in which current is provided to the first LED and a second state in which no current is provided to the first LED, and at least a first current sensor that is connected or connectable with the first LED so that the first current sensor and the first LED form a current path at least in the second state of the first controllable current source.

Abstract: Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing a NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.

Abstract: A radiotherapy apparatus is disclosed, with a linear accelerator for producing a beam of electrons, a target aligned with the electron beam, the target being capable of producing photons when electrons are incident thereon, and a material which is capable of producing neutrons when photons of sufficient energy are incident thereon. A neutron detector capable of providing a signal to a controller of the linear accelerator is provided, the controller being capable of varying the energy of the electrons of the electron beam.

Abstract: The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.

Abstract: A hair darkening dye composition, comprises: 2-98 parts by weight of hair dye; 1-99 parts by weight of darkening agent; 2-98 parts by weight of crosslinking agent; 2-98 parts by weight of emulsifier; 2-98 parts by weight of dyeing auxiliaries; and 0.1-40 parts by weight of pH regulator. The darkening agent is selected from one or more of chitin, chitosan, gelatin, silicon oil and resin. The chitin, chitosan and gelatin have a relative molecular weight of less than 2.7×104, and the silicon oil and resin have a refractive index of less than 1.55.

Abstract: The present invention is directed to a cleansing composition containing: (a) at least one anionic surfactant; (b) at least one amphoteric surfactant; (c) at least one amphoteric polymer; (d) at least one acrylate copolymer; (e) at least one silicone; (f) at least one alcohol ester; and (g) an insoluble component, and wherein the composition is preferably clear in appearance, free of cationic polymer, and has the insoluble component effectively suspended therein.

Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, a zinc source, and a preservative, as well as to methods of using and of making these compositions.

Abstract: Antiperspirant compositions that are suitable in particular for application with a roller applicator and contain water, at least one antiperspirant aluminum-zirconium-glycine complex and also L-valine, wherein the weight ratio of glycine to L-valine is in the range of about 20:1 to about 4:1, have a high antiperspirant efficacy and are tolerated very well on the skin at the same time.

Abstract: The present disclosure provides generally for sun defense nutriments that may allow participants to safely engage in sun activities and methods related to manufacturing sun defense nutriments. According to the present disclosure, sun defense nutriments may comprise sun defense attributes that may provide sun activity protection when the sun defense nutriment is ingested. In some embodiments, sun defense nutriments may be customized to provide effective protection measures for a particular sun activity. In some aspects, methods of manufacturing may allow for the generation of combinations of sun defense attribute contributors for production of sun defense nutriments. In some implementations, the combinations may be generated based on one or more criterion related to sun defense attributes, sun activities, flavors, or nutriment types, as non-limiting examples.

Abstract: A cosmetic emulsion composition for skincare, which comprises a. at least one anionic surfactant and/or a fatty acid soap, b. at least one animal wax and/or a derivative of an animal waxes, c. at least one vegetable oil, d. at least one C2-C6 polyol e. at least one natural thickener f. at least one extract from chamomile and g. allantoin, has excellent skin care properties (skin-soothing effect, moisturizing properties). Moreover, they are storage stable and have a pleasant texture.

Abstract: Stabilizing devices and methods of use for stabilizing spreading tools are provided. The stabilizing device includes a base having a first surface and a second surface, a first tower extending from the first surface having a first aperture formed therein, a second tower extending from the first surface having a second aperture formed therein, wherein the second tower is separated from the first tower by a tower span configured to receive a portion of the spreading tool, an engagement pin removably receivable through the first and second apertures, extend across the tower span, and configured to engage with a portion of a spreading tool, and a rail extending from the first surface and configured to stop movement of a spreading tool that is engaged with the engagement pin between the first and second towers.

Abstract: A safety restraint system for a person comprising two carabiners configured to receive at least one restraint element, each of the carabiners comprising a hook for receiving the element, a gate comprising a first branch forming a door and a second branch for actuating the door, a first means for locking the gate in a holding configuration. The system further comprising a transmission device connecting the carabiners together, the device arranged to make it impossible to switch from a state in which each of the carabiners is secured to an element to a state in which neither of the carabiners are secured to an element.

Abstract: A mobile firefighting system includes a water cannon enabled for spraying slush on or near a fire. The slush includes solid material (e.g., ice, solid fire retardant) that is projected farther than a liquid could be projected using high pressure. The slush has enhanced fire suppression and fire protection characteristics compared to a liquid. Multiple tanks add enhanced slush chilling capability (e.g., through sequenced chilling) and provide redundant backup systems. A mobile cannon includes multiple reducing nozzles that can be aimed by a rotating base and hydraulic cylinder (for raising and lowering). Continuous tracks and winches contribute to all-terrain capabilities.

Abstract: An alarm valve station includes a fire extinguishing system valve (1) having a housing (2, 3) which has a fluid inlet chamber (8), a fluid outlet chamber (9) and a closing body (4a) reciprocable between a blocking state and a release state, wherein the fluid inlet chamber (8) and the fluid outlet chamber (9) are separated from each other in the blocking state and communicate with each other in fluid-conducting relationship in the release state, one or more sensors, and an electronic evaluation unit (50) which is integrated in the housing (2, 3), arranged externally on the housing or arranged in the proximity of the fire extinguishing system valve (1), wherein the evaluation unit (50) is connected in signal-conducting relationship to the sensor or sensors for receiving data, is adapted for data processing into: state information and/or operating instructions and is adapted to transmit the state information and/or operating instructions to a display unit (40).

Abstract: This exercise assisting device (1) is provided with a grip member (3) that can be gripped by a hand and that extends in a tubular shape or in a columnar shape. The grip member (3) has a recessed part (31) configured so that, when the device is gripped by the hand, only a portion at which the middle finger is placed is recessed.

Abstract: A stair stepping apparatus comprising: a plurality of stairs forming a treadmill or endless belt on which a user steps, wherein each stair comprises: a first link comprised of a major step portion joined to a minor riser portion by a rigid elbow, and a second link comprised of major riser portion joined to a minor step portion by a rigid elbow.

Abstract: The sensor information acquisition unit acquires an angular velocity around an axis of a shaft portion of an exercise instrument from a sensor unit. An exercise analysis unit detects a timing of an impact of the exercise instrument. A calculation unit calculates a distance between a standard position set on a hitting surface of the exercise instrument and a position of the hitting based on the angular velocity at the time of an impact.

Abstract: Systems and methods for motion capture and analysis are described. The system may include a motion sensor unit configured to capture data associated with movement of an object. The motion sensor unit is configured to be directly or indirectly coupled to the movement object at a first location. The system also includes a processor to process the captured data to determine one or more values and to translate the data and/or values to correspond to a second location on the movement object located away from the first location. The data and/or values, including translated data and/or values, may be transmitted by wireless transmitter and displayed by a display unit.

Abstract: The present disclosure provides an electronic apparatus. The electronic apparatus includes a sensor and a processor electrically connected to the sensor and configured to generate information indicating a start of an activity when first data indicating that an activity of the electronic apparatus occurs is received from the sensor and generate information indicating a start of an exercise when second data indicating that the activity is associated with the exercise is received from the sensor.

Abstract: An electronic device, a system, and a method for determining a suitable workout in consideration of a context are provided. The electronic device includes a communication module comprising communication circuitry configured to communicate with at least one other electronic device; a display configured to provide a user interface; a memory configured to store instructions therein; and a processor electrically connected to the communication module, the display, and the instructions stored in the memory, when executed by the processor, cause the processor to receive a command for executing a workout program, to collect context data for a user, and to determine whether it is suitable for the user to perform planned workout content based on the collected context data.

Abstract: An object of the present invention is to provide a golf ball showing a low spin rate on driver shots and a high spin rate on approach shots. The present invention provides a golf ball having a low hardness part having a hardness in a range from 5 to 40 in Shore D hardness or a lowest hardness point in a core hardness distribution in a region located at a distance from 36.0% to 65.0% of a radius of the golf ball from a center point of the golf ball.

Abstract: The current invention is a golf ball retriever that enables an individual to pick up a golf ball without requiring the user to bend over. The golf ball retriever includes an extendable rod with a cup configured to receive a golf ball disposed at a distal end of the rod. In one embodiment, the extendable rod is in a telescopic arrangement movable between an extend position and a retracted position. In use, the rod is extended and the cup is pressed over the ball. The cup receives the ball, and the ball remains within the cup until removed by a user.

Abstract: A ball striking device, such as a golf club head, has a face with a striking surface configured for striking a ball and a channel extending across a portion of the sole. The channel may be recessed from adjacent surfaces of the sole and have a depth of recession from the adjacent surfaces of the sole, wherein the channel comprises a center portion extending across a center of the sole, a heel portion extending from a heel end of the center portion toward the heel, and a toe portion extending from a toe end of the center portion toward the toe, wherein the width and the depth of the center portion of the channel are substantially constant, and wherein the depth of the channel is greater at the heel and toe portions than at the center portion.